David R Croucher

David R Croucher

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David R Croucher

David R Croucher

Publications by authors named "David R Croucher"

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28Publications

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The extracellular matrix as a key regulator of intracellular signalling networks.

Br J Pharmacol 2019 01 19;176(1):82-92. Epub 2018 Apr 19.

The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Cancer Division, Darlinghurst, NSW, 2010, Australia.

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http://dx.doi.org/10.1111/bph.14195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284331PMC
January 2019

Dissecting Multi-protein Signaling Complexes by Bimolecular Complementation Affinity Purification (BiCAP).

J Vis Exp 2018 06 15(136). Epub 2018 Jun 15.

The Kinghorn Cancer Centre, Garvan Institute of Medical Research; St Vincent's Hospital Clinical School, University of New South Wales; School of Medicine and Medical Science, University College Dublin;

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http://dx.doi.org/10.3791/57109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101743PMC
June 2018

The Under-Appreciated Promiscuity of the Epidermal Growth Factor Receptor Family.

Front Cell Dev Biol 2016 22;4:88. Epub 2016 Aug 22.

Kinghorn Cancer Centre, Garvan Institute of Medical ResearchSydney, NSW, Australia; School of Medicine, University College DublinDublin, Ireland; St Vincent's Hospital Clinical School, University of New South WalesSydney, NSW, Australia.

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http://dx.doi.org/10.3389/fcell.2016.00088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992703PMC
September 2016

Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers.

Sci Signal 2016 07 12;9(436):ra69. Epub 2016 Jul 12.

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia. School of Medical Sciences, University of New South Wales, Sydney, New South Wales 2052, Australia.

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http://stke.sciencemag.org/lookup/doi/10.1126/scisignal.aaf0
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http://dx.doi.org/10.1126/scisignal.aaf0793DOI Listing
July 2016

PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells.

J Cell Sci 2016 Apr 12;129(7):1340-54. Epub 2016 Feb 12.

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales 2010, Australia St. Vincent's Clinical School, Faculty of Medicine, UNSW, Darlinghurst 2010, New South Wales, Australia

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http://dx.doi.org/10.1242/jcs.179754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852720PMC
April 2016

Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients.

Sci Signal 2015 Dec 22;8(408):ra130. Epub 2015 Dec 22.

Systems Biology Ireland, University College Dublin, Belfield, Dublin 4, Ireland. The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia. St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales 2052, Australia.

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http://dx.doi.org/10.1126/scisignal.aab0990DOI Listing
December 2015

Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions.

BMC Bioinformatics 2014 Sep 17;15:305. Epub 2014 Sep 17.

School of Medicine and Medical Science, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/1471-2105-15-305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262234PMC
September 2014

t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions.

Brain Res 2014 May 25;1565:63-73. Epub 2014 Mar 25.

Australian Centre for Blood Diseases, Monash University, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2014.03.027DOI Listing
May 2014

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway.

Cancer Res 2013 Mar 1;73(6):1969-80. Epub 2013 Feb 1.

Cancer Research Program, The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1472DOI Listing
March 2013

Signalling by protein phosphatases and drug development: a systems-centred view.

FEBS J 2013 Jan 14;280(2):751-65. Epub 2012 Mar 14.

Systems Biology Ireland, University College Dublin, Belfield, Ireland.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08522.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368988PMC
January 2013

Crosstalk and signaling switches in mitogen-activated protein kinase cascades.

Front Physiol 2012 18;3:355. Epub 2012 Sep 18.

Systems Biology Ireland, University College Dublin Dublin, Ireland.

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http://journal.frontiersin.org/article/10.3389/fphys.2012.00
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http://dx.doi.org/10.3389/fphys.2012.00355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449335PMC
October 2012

Dependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of SerpinE1 and SerpinB2 in cancer.

J Biol Chem 2011 Jul 23;286(27):24467-75. Epub 2011 May 23.

School of Biological Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.

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http://dx.doi.org/10.1074/jbc.M111.225706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129226PMC
July 2011

Differential endocytosis of tissue plasminogen activator by serpins PAI-1 and PAI-2 on human peripheral blood monocytes.

Thromb Haemost 2010 Dec 13;104(6):1133-42. Epub 2010 Sep 13.

School of Biological Sciences, University of Wollongong, Northfields Avenue, Wollongong, New South Wales, Australia.

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http://www.thieme-connect.de/DOI/DOI?10.1160/TH10-02-0121
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http://dx.doi.org/10.1160/TH10-02-0121DOI Listing
December 2010

Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

Cancer Res 2010 Nov 21;70(22):9391-401. Epub 2010 Sep 21.

Cancer Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital Clinical School and Bioanalytical Mass Spectrometry Facility, University of New South Wales, Sydney, New South Wales, Australia.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-0911DOI Listing
November 2010

Plasminogen activator inhibitor type 2 inhibits cell surface associated tissue plasminogen activator in vitro: potential receptor interactions.

Thromb Haemost 2008 Aug;100(2):319-29

School of Biological Sciences, University of Wollongong, NSW, Australia.

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August 2008

Revisiting the biological roles of PAI2 (SERPINB2) in cancer.

Nat Rev Cancer 2008 Jul 12;8(7):535-45. Epub 2008 Jun 12.

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales, Australia 2010.

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http://dx.doi.org/10.1038/nrc2400DOI Listing
July 2008

A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells.

Biochem J 2007 Dec;408(2):203-10

School of Biological Sciences, University of Wollongong, NSW 2522, Australia.

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http://dx.doi.org/10.1042/BJ20070767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267350PMC
December 2007