Publications by authors named "David R Booth"

66Publications

Vitamin D and its Effects on DNA Methylation in Development, Aging, and Disease.

Authors:
Lawrence T C Ong David R Booth Grant P Parnell

Mol Nutr Food Res 2020 Oct 20:e2000437. Epub 2020 Oct 20.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, The University of Sydney, 176 Hawkesbury Rd, Westmead, New South Wales, 2145, Australia.

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October 2020

Regulation of the methylome in differentiation from adult stem cells may underpin vitamin D risk in MS.

Authors:
Lawrence T C Ong Grant P Parnell Kelly Veale Graeme J Stewart Christopher Liddle David R Booth

Genes Immun 2020 Nov 9;21(5):335-347. Epub 2020 Oct 9.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, The University of Sydney, 176 Hawkesbury Rd, Westmead, NSW, 2145, Australia.

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November 2020

The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis.

Authors:
Ali Afrasiabi Grant P Parnell Sanjay Swaminathan Graeme J Stewart David R Booth

Sci Rep 2020 01 13;10(1):193. Epub 2020 Jan 13.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.

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January 2020

Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein-Barr Virus hypomethylated regions.

Authors:
Lawrence T C Ong Grant P Parnell Ali Afrasiabi Graeme J Stewart Sanjay Swaminathan David R Booth

Genes Immun 2020 02 16;21(2):91-99. Epub 2019 Oct 16.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, The University of Sydney, 176 Hawkesbury Rd, Westmead, NSW, 2145, Australia.

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February 2020

Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndrome.

Authors:
Stephanie Trend Anderson P Jones Lilian Cha Matthew N Cooper Sian Geldenhuys Marzena J Fabis-Pedrini William M Carroll Judith M Cole David R Booth Robyn M Lucas Martyn A French Scott N Byrne Allan G Kermode Prue H Hart

Sci Rep 2019 05 28;9(1):7980. Epub 2019 May 28.

Telethon Kids Institute, University of Western Australia, Perth, WA, Australia.

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May 2019

Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility.

Authors:
Ali Afrasiabi Grant P Parnell Nicole Fewings Stephen D Schibeci Monica A Basuki Ramya Chandramohan Yuan Zhou Bruce Taylor David A Brown Sanjay Swaminathan Fiona C McKay Graeme J Stewart David R Booth

Genome Med 2019 04 30;11(1):26. Epub 2019 Apr 30.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, Australia.

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April 2019

The latitude-dependent autoimmune disease risk genes ZMIZ1 and IRF8 regulate mononuclear phagocytic cell differentiation in response to vitamin D.

Authors:
Grant P Parnell Stephen D Schibeci Nicole L Fewings Ali Afrasiabi Samantha P L Law Shanuka Samaranayake Jing Hui Kh'ng Yee Hsu Fong David A Brown Christopher Liddle Graeme J Stewart David R Booth

Hum Mol Genet 2019 01;28(2):269-278

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Westmead NSW, Australia.

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January 2019

Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosis.

Authors:
Lilian Cha Anderson P Jones Stephanie Trend Scott N Byrne Marzena J Fabis-Pedrini William M Carroll Robyn M Lucas Judith M Cole David R Booth Allan G Kermode Prue H Hart

Clin Transl Immunology 2018 16;7(8):e1037. Epub 2018 Aug 16.

Telethon Kids Institute University of Western Australia Perth WA Australia.

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August 2018

Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome.

Authors:
Stephanie Trend Anderson P Jones Lilian Cha Scott N Byrne Sian Geldenhuys Marzena J Fabis-Pedrini William M Carroll Judith M Cole David R Booth Robyn M Lucas Allan G Kermode Martyn A French Prue H Hart

Front Immunol 2018 13;9:1590. Epub 2018 Jul 13.

Telethon Kids Institute, University of Western Australia, Perth, WA, Australia.

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July 2018

A randomised, controlled clinical trial of narrowband UVB phototherapy for clinically isolated syndrome: The PhoCIS study.

Authors:
Prue H Hart Anderson P Jones Stephanie Trend Lilian Cha Marzena J Fabis-Pedrini Matthew N Cooper Catherine d'Este Sian Geldenhuys William M Carroll Scott N Byrne David R Booth Judith M Cole Robyn M Lucas Allan G Kermode

Mult Scler J Exp Transl Clin 2018 Apr-Jun;4(2):2055217318773112. Epub 2018 Apr 27.

Centre for Neuromuscular and Neurological Disorders, Perron Institute for Neurological and Translational Science, University of Western Australia, Sir Charles Gairdner Hospital, Australia.

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April 2018

Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis: A Study of Humans and a Transgenic Mouse Model.

Authors:
Rebecca K Sheean Fiona C McKay Erika Cretney Christopher R Bye Nirma D Perera Doris Tomas Richard A Weston Karlene J Scheller Elvan Djouma Parvathi Menon Stephen D Schibeci Najwa Marmash Justin J Yerbury Stephen L Nutt David R Booth Graeme J Stewart Mathew C Kiernan Steve Vucic Bradley J Turner

JAMA Neurol 2018 06;75(6):681-689

Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.

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June 2018

GPR65 inhibits experimental autoimmune encephalomyelitis through CD4 T cell independent mechanisms that include effects on iNKT cells.

Authors:
Rushika C Wirasinha Dipti Vijayan Nicola J Smith Grant P Parnell Alexander Swarbrick Robert Brink Cecile King Graeme Stewart David R Booth Marcel Batten

Immunol Cell Biol 2018 02 19;96(2):128-136. Epub 2017 Dec 19.

Immunology Division, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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February 2018

Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis.

Authors:
Anderson P Jones Stephanie Trend Scott N Byrne Marzena J Fabis-Pedrini Sian Geldenhuys David Nolan David R Booth William M Carroll Robyn M Lucas Allan G Kermode Prue H Hart

Clin Transl Immunology 2017 May 26;6(5):e143. Epub 2017 May 26.

Telethon Kids Institute, University of Western Australia, West Perth, Western Australia, Australia.

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May 2017

Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI.

Authors:
Stephanie Trend Anderson P Jones Sian Geldenhuys Scott N Byrne Marzena J Fabis-Pedrini David Nolan David R Booth William M Carroll Robyn M Lucas Allan G Kermode Prue H Hart

Int J Mol Sci 2017 Jun 15;18(6). Epub 2017 Jun 15.

Telethon Kids Institute, University of Western Australia, Perth, WA 6008, Australia.

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June 2017

The Multiple Sclerosis (MS) Genetic Risk Factors Indicate both Acquired and Innate Immune Cell Subsets Contribute to MS Pathogenesis and Identify Novel Therapeutic Opportunities.

Authors:
Grant P Parnell David R Booth

Front Immunol 2017 18;8:425. Epub 2017 Apr 18.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Westmead, NSW, Australia.

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April 2017

IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis.

Authors:
Mohammed Eslam Duncan McLeod Kebitsaone Simon Kelaeng Alessandra Mangia Thomas Berg Khaled Thabet William L Irving Gregory J Dore David Sheridan Henning Grønbæk Maria Lorena Abate Rune Hartmann Elisabetta Bugianesi Ulrich Spengler Angela Rojas David R Booth Martin Weltman Lindsay Mollison Wendy Cheng Stephen Riordan Hema Mahajan Janett Fischer Jacob Nattermann Mark W Douglas Christopher Liddle Elizabeth Powell Manuel Romero-Gomez Jacob George

Nat Genet 2017 May 10;49(5):795-800. Epub 2017 Apr 10.

Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Sydney, New South Wales, Australia.

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May 2017

Narrowband UVB Phototherapy for Clinically Isolated Syndrome: A Trial to Deliver the Benefits of Vitamin D and Other UVB-Induced Molecules.

Authors:
Prue H Hart Robyn M Lucas David R Booth William M Carroll David Nolan Judith M Cole Anderson P Jones Allan G Kermode

Front Immunol 2017 24;8. Epub 2017 Jan 24.

Centre for Neuromuscular and Neurological Disorders, Western Australian Neuroscience Research Institute, University of Western Australia, Sir Charles Gairdner Hospital, Perth, WA, Australia; Institute for Immunology and Infectious Disease, Murdoch University, Perth, WA, Australia.

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January 2017

Differences in common heritable blood immune cell populations may underlie MS susceptibility and progression.

Authors:
David R Booth Nicole L Fewings Grant P Parnell Fiona C McKay Graeme J Stewart

Mult Scler J Exp Transl Clin 2016 Jan-Dec;2:2055217316637087. Epub 2016 Mar 11.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Australia.

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March 2016

Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes.

Authors:
Mohammed Eslam Alessandra Mangia Thomas Berg Henry Lik Yuen Chan William L Irving Gregory J Dore Maria Lorena Abate Elisabetta Bugianesi Leon A Adams Mustafa A M Najim Luca Miele Martin Weltman Lindsay Mollison Wendy Cheng Stephen Riordan Janett Fischer Manuel Romero-Gomez Ulrich Spengler Jacob Nattermann Antony Rahme David Sheridan David R Booth Duncan McLeod Elizabeth Powell Christopher Liddle Mark W Douglas David van der Poorten Jacob George

Hepatology 2016 07 30;64(1):34-46. Epub 2016 Mar 30.

Storr Liver Centre, Westmead Millennium Institute and Westmead Hospital, University of Sydney, NSW, Australia.

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July 2016

The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies.

Authors:
Fiona C McKay Prudence N Gatt Nicole Fewings Grant P Parnell Stephen D Schibeci Monica A I Basuki Joseph E Powell Anita Goldinger Marzena J Fabis-Pedrini Allan G Kermode Therese Burke Steve Vucic Graeme J Stewart David R Booth

Clin Immunol 2016 Feb 4;163:96-107. Epub 2016 Jan 4.

Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales 2145, Australia. Electronic address:

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February 2016