David P Carbone

David P Carbone

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David P Carbone

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Change in neutrophil to lymphocyte ratio during immunotherapy treatment is a non-linear predictor of patient outcomes in advanced cancers.

J Cancer Res Clin Oncol 2019 Oct 31;145(10):2541-2546. Epub 2019 Jul 31.

Division of Medical Oncology, Department of Internal Medicine, Ohio State University Wexner Medical Center, 320 W 10th Ave, A450B Starling Loving Hall, Columbus, OH, 43210, USA.

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http://dx.doi.org/10.1007/s00432-019-02982-4DOI Listing
October 2019

Safety of dose-reduced pemetrexed in patients with renal insufficiency.

J Oncol Pharm Pract 2019 Jul 5;25(5):1125-1129. Epub 2018 Jun 5.

3 Department of Medicine, Section of Hematology and Oncology at The James Cancer Hospital and Solove Research Institute at The Ohio State University, Columbus, USA.

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http://journals.sagepub.com/doi/10.1177/1078155218780507
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http://dx.doi.org/10.1177/1078155218780507DOI Listing
July 2019

The Effect of LKB1 Activity on the Sensitivity to PI3K/mTOR Inhibition in Non-Small Cell Lung Cancer.

J Thorac Oncol 2019 Jun 27;14(6):1061-1076. Epub 2019 Feb 27.

Division of Medical Oncology, Department of Internal Medicine, James Thoracic Center, The Ohio State University, Columbus, Ohio. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864193015
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http://dx.doi.org/10.1016/j.jtho.2019.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602060PMC
June 2019

DLL3: an emerging target in small cell lung cancer.

J Hematol Oncol 2019 Jun 18;12(1):61. Epub 2019 Jun 18.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.

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http://dx.doi.org/10.1186/s13045-019-0745-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582566PMC
June 2019

Co-Expression Analysis Reveals Mechanisms Underlying the Varied Roles of NOTCH1 in NSCLC.

J Thorac Oncol 2019 Feb 5;14(2):223-236. Epub 2018 Nov 5.

Department of Internal Medicine, James Thoracic Center, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.10.162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348021PMC
February 2019

Novel mechanism of resistance to targeted therapies in lung cancer.

Mol Cell Oncol 2019 30;6(1):1551015. Epub 2018 Dec 30.

Department of Internal Medicine, Division of Medical Oncology, The Ohio State University Medical Center, Columbus, OH USA.

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http://dx.doi.org/10.1080/23723556.2018.1551015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370384PMC
December 2018

Incidence, Risk Factors, and Effect on Survival of Immune-related Adverse Events in Patients With Non-Small-cell Lung Cancer.

Clin Lung Cancer 2018 11 22;19(6):e893-e900. Epub 2018 Aug 22.

Division of Medical Oncology, Ohio State University Wexner Medical Center, James Cancer Hospital and Solove Research Institute, Columbus, OH.

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http://dx.doi.org/10.1016/j.cllc.2018.08.008DOI Listing
November 2018

Identifying patterns of care for elderly patients with non-surgically treated stage III non-small cell lung cancer: an analysis of the national cancer database.

Radiat Oncol 2018 Oct 5;13(1):196. Epub 2018 Oct 5.

Department of Radiation Oncology, at the Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, 460 W. 10th Avenue, Columbus, OH, 43210, USA.

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https://ro-journal.biomedcentral.com/articles/10.1186/s13014
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http://dx.doi.org/10.1186/s13014-018-1142-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173899PMC
October 2018

Real-World Treatment Patterns, Overall Survival, and Occurrence and Costs of Adverse Events Associated With Second-Line Therapies for Medicare Patients With Advanced Non-Small-Cell Lung Cancer.

Clin Lung Cancer 2018 09 6;19(5):e783-e799. Epub 2018 Jun 6.

The Ohio State University Comprehensive Cancer Center and James Thoracic Oncology Center, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1016/j.cllc.2018.05.016DOI Listing
September 2018

Lung Cancer Patients with Germline Mutations Detected by Next-Generation Sequencing and/or Liquid Biopsy.

J Thorac Oncol 2018 02 5;13(2):e17-e19. Epub 2017 Oct 5.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864173276
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http://dx.doi.org/10.1016/j.jtho.2017.09.1962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910030PMC
February 2018

Global Transcriptome Analysis of RNA Abundance Regulation by ADAR in Lung Adenocarcinoma.

EBioMedicine 2018 Jan 6;27:167-175. Epub 2017 Dec 6.

Department of Biomedical Informatics, The Ohio State University, Columbus, OH, United States; Current Address: Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828651PMC
January 2018

Prognostic Value of Primary Tumor Volume Changes on kV-CBCT during Definitive Chemoradiotherapy for Stage III Non-Small Cell Lung Cancer.

J Thorac Oncol 2017 12 24;12(12):1779-1787. Epub 2017 Aug 24.

Department of Radiation Oncology, Division of Medical Oncology, The Ohio State University Wexner Medical Center, Arthur G. James Comprehensive Cancer Center and Richard J. Solove Research Institute, Columbus, Ohio. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864173068
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http://dx.doi.org/10.1016/j.jtho.2017.08.010DOI Listing
December 2017

Blood-based biomarkers in lung cancer: prognosis and treatment decisions.

Transl Lung Cancer Res 2017 Dec;6(6):708-712

Division of Medical Oncology, Department of Medicine, The Ohio State University Wexner Medical Center, Columbus, USA.

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http://dx.doi.org/10.21037/tlcr.2017.09.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709136PMC
December 2017

Ibuprofen and fatal lung cancer: A brief report of the prospective results from the Third National Health and Nutrition Examination Survey (NHANES III).

Mol Clin Oncol 2017 Jun 5;6(6):917-920. Epub 2017 May 5.

Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.3892/mco.2017.1239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451865PMC
June 2017

First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.

N Engl J Med 2017 06;376(25):2415-2426

From the Ohio State University Comprehensive Cancer Center, Columbus (D.P.C.); LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf (M.R.), and Thoraxklinik, Heidelberg University Hospital, Heidelberg (M.S.) - both in Germany; Hospital Universitario Doce de Octubre, Centro Nacional de Investigaciones Oncológicas and Universidad Complutense, Madrid (L.P.-A., J.C.J.), Vall d'Hebron University Hospital, Barcelona (E.F.), and Hospital Universitario Insular de Gran Canaria, Las Palmas (D.R.-A.) - all in Spain; H. Lee Moffitt Cancer Center, Tampa, FL (B.C.); Vanderbilt University Medical Center, Nashville (L. Horn); Antoni van Leeuwenhoek Ziekenhuis, Amsterdam (M.M.H.), and University of Groningen, Universitair Medisch Centrum Groningen, Groningen (T.J.N.H.) - both in the Netherlands; Prof. Dr. Ion Chiricuta Institute of Oncology and University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania (T.-E.C.); Baptist Health Lexington, Lexington, KY (F.B.); Duke University, Durham, NC (N.R.); Lehigh Valley Health Network, Allentown (S.N.), Fox Chase Cancer Center, Philadelphia (H.B.), and University of Pittsburgh Medical Center Cancer Center, Pittsburgh (L.C.V., M.A.S.) - all in Pennsylvania; Juravinski Cancer Centre, Hamilton, ON, Canada (R.J.); Oncology Department, Lausanne University Hospital, Lausanne, Switzerland (S.P.); Santa Maria Hospital, Terni, Italy (E.M.); Hollings Cancer Center, Charleston, SC (J.M.W.); Department of Thoracic-Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston (G.R.B.); Klinika Pneumologie a Hrudní Chirurgie, Nemocnice Na Bulovce, Prague, Czech Republic (L. Havel, J.K.); and Bristol-Myers Squibb, Princeton, NJ (H.C., W.J.G., P.B., A.C.C.).

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http://dx.doi.org/10.1056/NEJMoa1613493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487310PMC
June 2017

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

J Clin Oncol 2017 May 13;35(13):1403-1410. Epub 2017 Mar 13.

Oliver Gautschi, Kristin Zeidler, and Joachim Diebold, Lucerne Cantonal Hospital, Luzern; Patrizia Froesch, Ente Ospedaliero Cantonale, Bellinzona; Martin Früh, Kantonsspital St Gallen, St Gallen; Sacha I. Rothschild, University Hospital Basel, Basel, Switzerland; Julie Milia and Julien Mazières, Hôpital Larrey; Thomas Filleron, Institut Universitaire du Cancer, Claudius Regaud, Toulouse; Benjamin Besse and Jordi Remon-Masip, Institute Gustave Roussy, Villejuif; Gérard Zalcman, University Hospital Bichat, Paris; Isabelle Monnet, Centre Hospitalier Intercommunal de Creteil, Creteil; Florian Cabillic, Université de Rennes 1, Rennes, France; Juergen Wolf and Sebastian Michels, Center for Integrated Oncology, Cologne; Georg Pall, Fachkliniken Wangen, Wangen Im Allgäu; Arne Warth, Heidelberg University Hospital; Thomas Muley, Thoraxklinik at University of Heidelberg and Translational Lung Research Center, Heidelberg, Germany; David P. Carbone and Dwight Owen, Ohio State University Comprehensive Cancer Center, Columbus; Vamsidhar Velcheti, Cleveland Clinic, Pepper Pike, OH; Ross Camidge and Vignhesh Narayanan, University of Colorado, Denver; Robert C. Doebele, University of Colorado, Aurora, CO; Pasi A. Janne and Mark M. Awad, Dana-Farber Cancer Institute, Boston, MA; Daniel D. Karp, The University of Texas MD Anderson Cancer Center, Houston, TX; Heather A. Wakelee and Joel W. Neal, Stanford University, Stanford; Sai-Hong Ignatius Ou, University of California, Irvine, Orange; David R. Gandara and Jonathan W. Riess, University of California, Davis Cancer Center, Sacramento, CA; Alexander Drilon, Memorial Sloan Kettering Cancer Center, New York, NY; Nir Peled, Davidoff Cancer Center, Petach Tiqwa, Israël; Chul-Cho Byoung, Yonseï Cancer Center, Seoul, Republic of Korea; Michael Van Den Heuvel, Netherlands Cancer Institute, Amsterdam, the Netherlands; Tony S.K. Mok, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China; James C.H. Yang and Jin-Yuan Shih, National Taiwan University Hospital, Taipei, Republic of China; Sanjay Popat, Royal Marsden Hospital, London, United Kingdom; and Rafael Rosell and Niki Karachaliou, Catalan Institute of Oncology, Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2016.70.9352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559893PMC
May 2017

Non-small cell lung cancer genomics around the globe: focus on ethnicity.

J Thorac Dis 2017 Apr;9(4):E392-E394

The James Cancer Center, The Ohio State University Medical Center, Columbus, OH 43210, USA.

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http://dx.doi.org/10.21037/jtd.2017.03.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418295PMC
April 2017

Costs of Diagnostic Assessment for Lung Cancer: A Medicare Claims Analysis.

Clin Lung Cancer 2017 01 21;18(1):e27-e34. Epub 2016 Jul 21.

Division of Thoracic Oncology, Department of Internal Medicine, Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1016/j.cllc.2016.07.006DOI Listing
January 2017

A Transcriptional Signature Identifies LKB1 Functional Status as a Novel Determinant of MEK Sensitivity in Lung Adenocarcinoma.

Cancer Res 2017 01 7;77(1):153-163. Epub 2016 Nov 7.

Department of Internal Medicine, James Thoracic Center, Ohio State University, Columbus, Ohio.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-16-1639DOI Listing
January 2017

Relationship between Overall Survival and Response or Progression-Free Survival in Advanced Non-Small Cell Lung Cancer Patients Treated with Anti-PD-1/PD-L1 Antibodies.

J Thorac Oncol 2016 11 3;11(11):1927-1939. Epub 2016 Aug 3.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.07.017DOI Listing
November 2016

Treatment Patterns for Advanced Non-Small-cell Lung Cancer After Platinum-containing Therapy in U.S. Community Oncology Clinical Practice.

Clin Lung Cancer 2016 09 29;17(5):449-460.e7. Epub 2016 Mar 29.

Medical Oncology, The James, The Ohio State University Comprehensive Cancer Center, Columbus, OH.

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http://dx.doi.org/10.1016/j.cllc.2016.03.008DOI Listing
September 2016

Predictive Markers for the Efficacy of Anti-PD-1/PD-L1 Antibodies in Lung Cancer.

J Thorac Oncol 2016 07 2;11(7):976-88. Epub 2016 Mar 2.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.02.015DOI Listing
July 2016

Promise of Immunotherapy in Lung Cancer.

Prog Tumor Res 2015 4;42:95-109. Epub 2015 Sep 4.

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http://dx.doi.org/10.1159/000437179DOI Listing
March 2016

PDL1 Regulation by p53 via miR-34.

J Natl Cancer Inst 2016 Jan 17;108(1). Epub 2015 Nov 17.

Departments of Experimental Radiation Oncology (MAC, DV, XW, YY), Experimental Therapeutics (CI, GAC), and Radiation Oncology (RK, DRG, SK, JWW), The University of Texas MD Anderson Cancer Center, Houston, TX; Mirna Therapeutics, Inc., Austin, TX (HJP, KK, DM, AGB); Ohio State University, Columbus, OH (LA, DPC, KS); Texas Veterinary Pathology Associates (Houston), Houston, TX (DKG).

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http://dx.doi.org/10.1093/jnci/djv303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862407PMC
January 2016

Akt Kinase-Interacting Protein 1 Signals through CREB to Drive Diffuse Malignant Mesothelioma.

Cancer Res 2015 Oct 20;75(19):4188-97. Epub 2015 Aug 20.

Department of Internal Medicine, The Ohio State University Medical Center, Columbus, Ohio.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0858DOI Listing
October 2015

Somatic Mutation Spectrum of Non-Small-Cell Lung Cancer in African Americans: A Pooled Analysis.

J Thorac Oncol 2015 Oct;10(10):1430-6

*Department of Internal Medicine, James Thoracic Center, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio; †Department of Internal Medicine, Meharry Medical College, Nashville, Tennessee; ‡Department of Internal Medicine, Baptist Center for Cancer Care, Columbus, Mississippi; §Department of Pathology, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee; ‖Pathology Associates of Saint Thomas, Nashville, Tennessee; ¶Department of Internal Medicine, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan; #GenomOncology, Cleveland, Ohio; ††Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio; and ‡‡Department of Biomedical Informatics, Biomedical Informatics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

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http://dx.doi.org/10.1097/JTO.0000000000000650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618391PMC
October 2015

Non-Small-Cell Lung Cancer: Role of the Immune System and Potential for Immunotherapy.

J Thorac Oncol 2015 Jul;10(7):974-84

*Ohio State University Medical Center, Columbus, Ohio; †University of California Davis Comprehensive Cancer Center, Sacramento, California; ‡H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida; §Comprehensive Cancer Center, Medical University of Vienna General Hospital, Vienna, Austria; and ‖Instituto de Biomedicina de Sevilla, Seville, Spain.

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http://dx.doi.org/10.1097/JTO.0000000000000551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618296PMC
July 2015

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2015 Jun 20;33(18):2004-12. Epub 2015 Apr 20.

Scott N. Gettinger and Mario Sznol, Yale Cancer Center, New Haven, CT; Leora Horn, David P. Carbone, and Jeffrey A. Sosman, Vanderbilt University Medical Center; David R. Spigel, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Leena Gandhi, David M. Jackman, and F. Stephen Hodi, Dana-Farber Cancer Institute; Rebecca S. Heist and Lecia V. Sequist, Massachusetts General Hospital Cancer Center; David F. McDermott, Beth Israel Deaconess Medical Center, Boston, MA; Scott J. Antonia and Mary C. Pinder-Schenck, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Naiyer A. Rizvi, Richard D. Carvajal, and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; David C. Smith, University of Michigan, Ann Arbor, MI; Philip Leming, Christ Hospital Cancer Center, Cincinnati, OH; Suzanne L. Topalian, Drew M. Pardoll, and Julie R. Brahmer, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; and Vindira Sankar, Christoph M. Ahlers, Mark Salvati, Jon M. Wigginton, Georgia D. Kollia, and Ashok K. Gupta, Bristol-Myers Squibb, Princeton, NJ.

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http://jco.ascopubs.org/content/early/2015/04/15/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.3708
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http://dx.doi.org/10.1200/JCO.2014.58.3708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672027PMC
June 2015

Genomic Characterization of Non-Small-Cell Lung Cancer in African Americans by Targeted Massively Parallel Sequencing.

J Clin Oncol 2015 Jun 27;33(17):1966-73. Epub 2015 Apr 27.

Luiz H. Araujo, Cynthia Timmers, Erica Hlavin Bell, Konstantin Shilo, Weiqiang Zhao, Jianying Zhang, Ayse S. Yilmaz, Tom Liu, Kevin Coombes, Joseph Amann, and David P. Carbone, The Ohio State University Comprehensive Cancer Center, Columbus; Thanemozhi G. Natarajan and Clinton J. Miller, GenomOncology, Cleveland, OH; Philip E. Lammers, Meharry Medical College, Nashville, TN.

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http://dx.doi.org/10.1200/JCO.2014.59.2444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451177PMC
June 2015

Non-small-cell lung cancer.

Nat Rev Dis Primers 2015 05 21;1:15009. Epub 2015 May 21.

Catalan Institute of Oncology, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.

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http://www.nature.com/articles/nrdp20159
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http://dx.doi.org/10.1038/nrdp.2015.9DOI Listing
May 2015

Mechanisms of and strategies for overcoming resistance to anti-vascular endothelial growth factor therapy in non-small cell lung cancer.

Biochim Biophys Acta 2015 Apr 15;1855(2):193-201. Epub 2015 Jan 15.

The Ohio State University Medical Center, Columbus, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2015.01.003DOI Listing
April 2015

EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling.

Cancer Res 2014 Oct 14;74(19):5572-84. Epub 2014 Aug 14.

Department of Internal Medicine, The Ohio State University Medical Center, Columbus, Ohio.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263272PMC
October 2014

LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.

J Thorac Oncol 2014 Jun;9(6):794-804

Departments of *Cancer Biology and §Biostatistics, Vanderbilt University, Nashville, Tennessee; †Department of Internal Medicine, James Thoracic Center, Ohio State University, Columbus, Ohio; and ‡University of Kentucky College of Dentistry, Lexington, Kentucky.

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http://dx.doi.org/10.1097/JTO.0000000000000173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026179PMC
June 2014

Highlights from the latest articles in lung cancer personalized medicine.

Per Med 2014 Jun;11(4):377-379

Pulmonary, Allergy, Critical Care & Sleep Medicine, The Ohio State University Columbus, OH 43210, USA.

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http://dx.doi.org/10.2217/pme.14.18DOI Listing
June 2014

Acquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1.

Cell Rep 2014 May 9;7(4):999-1008. Epub 2014 May 9.

Yale Cancer Center, Yale University School of Medicine, New Haven, CT 06510, USA; Department of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA; Department of Medicine (Medical Oncology), Yale University School of Medicine, New Haven, CT 06510, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074596PMC
May 2014

An era of lung cancer iconoclasts.

Authors:
David P Carbone

J Thorac Oncol 2014 Apr;9(4):436-7

James Thoracic Center, International Association for the Study of Lung Cancer, The Ohio State Wexner Medical Center, Columbus, Ohio.

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http://dx.doi.org/10.1097/JTO.0000000000000121DOI Listing
April 2014

The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma.

Tumour Biol 2014 Feb 13;35(2):973-85. Epub 2013 Sep 13.

First Department of Internal Medicine, Sapporo Medical University, S-1, W-16, Chuo-ku, Sapporo, 060-8543, Japan,

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http://dx.doi.org/10.1007/s13277-013-1131-2DOI Listing
February 2014

Reducing lung cancer mortality: 2014 update.

Semin Oncol 2014 Feb 12;41(1):3-4. Epub 2013 Dec 12.

Director, James Thoracic Center James Cancer Center The Ohio State University Medical Center Columbus, OH Guest Editors.

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https://linkinghub.elsevier.com/retrieve/pii/S00937754130021
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http://dx.doi.org/10.1053/j.seminoncol.2013.12.004DOI Listing
February 2014

From the guest editors: management of locally advanced lung cancer.

Cancer J 2013 May-Jun;19(3):199

James Thoracic Center and James Cancer Center, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1097/PPO.0b013e318299d234DOI Listing
December 2013

Research Highlights: Highlights from the latest articles in translating genomics to clinical practice in lung cancer.

Per Med 2013 Jun;10(4):329-331

Division of Medical Oncology, James Comprehensive Cancer Center, Wexner Medical Center at the Ohio State University, Columbus, OH 43210, USA. .

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https://www.futuremedicine.com/doi/10.2217/pme.13.23
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http://dx.doi.org/10.2217/pme.13.23DOI Listing
June 2013

ALDH7A1 expression is associated with recurrence in patients with surgically resected non-small-cell lung carcinoma.

Future Oncol 2013 May;9(5):737-45

Department of Radiation Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.2217/fon.13.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341386PMC
May 2013

Identifying barriers associated with enrollment of patients with lung cancer into clinical trials.

Clin Lung Cancer 2013 Jan 15;14(1):14-8. Epub 2012 May 15.

Vanderbilt Ingram Cancer Center, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.cllc.2012.03.008DOI Listing
January 2013

Sonic hedgehog pathway expression in non-small cell lung cancer.

Ther Adv Med Oncol 2012 Sep;4(5):225-33

Division of Radiation Oncology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1177/1758834012450362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424496PMC
September 2012

Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis.

J Pathol 2012 Aug 6;227(4):456-69. Epub 2012 Jun 6.

Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1002/path.4039DOI Listing
August 2012

Effects of cancer-associated EPHA3 mutations on lung cancer.

J Natl Cancer Inst 2012 Aug 24;104(15):1182-97. Epub 2012 Jul 24.

Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1093/jnci/djs297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611812PMC
August 2012

Long-term smoking mediated down-regulation of Smad3 induces resistance to carboplatin in non-small cell lung cancer.

Neoplasia 2012 Jul;14(7):644-55

Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421960PMC
http://dx.doi.org/10.1593/neo.12548DOI Listing
July 2012

Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells.

Int J Radiat Oncol Biol Phys 2012 Mar 22;82(3):e563-72. Epub 2011 Dec 22.

Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN 37232-5671, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2011.06.1999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271860PMC
March 2012

Smoking attenuates transforming growth factor-β-mediated tumor suppression function through downregulation of Smad3 in lung cancer.

Cancer Prev Res (Phila) 2012 Mar 9;5(3):453-63. Epub 2012 Jan 9.

Department of Surgery, Vanderbilt University School of Medicine, 1161 21st Avenue South, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299594PMC
March 2012

Adjuvant therapy in non-small cell lung cancer: future treatment prospects and paradigms.

Clin Lung Cancer 2011 Sep 10;12(5):261-71. Epub 2011 Aug 10.

Thoracic Oncology Center, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15257304110013
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http://dx.doi.org/10.1016/j.cllc.2011.06.002DOI Listing
September 2011

Translating cancer complexity to clinical decisions.

Authors:
David P Carbone

J Thorac Oncol 2011 Sep;6(9):1455-6; author reply 1456-7

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http://dx.doi.org/10.1097/JTO.0b013e3182291953DOI Listing
September 2011

Methods for peptide and protein quantitation by liquid chromatography-multiple reaction monitoring mass spectrometry.

Mol Cell Proteomics 2011 Jun 27;10(6):M110.006593. Epub 2011 Feb 27.

Jim Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1074/mcp.M110.006593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108838PMC
June 2011

Inhibition of JAK2 signaling by TG101209 enhances radiotherapy in lung cancer models.

J Thorac Oncol 2011 Apr;6(4):699-706

Department of Radiation Oncology Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232-5671, USA.

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http://dx.doi.org/10.1097/JTO.0b013e31820d9d11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104103PMC
April 2011

Lung cancer diagnosis from proteomic analysis of preinvasive lesions.

Cancer Res 2011 Apr 12;71(8):3009-17. Epub 2011 Apr 12.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Mass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6838, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110721PMC
April 2011

Lung cancer in 2010: One size does not fit all.

Nat Rev Clin Oncol 2011 Feb;8(2):68-70

Vanderbilt-Ingram Cancer Center, 2220 Pierce Avenue, Preston Research Building 685, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1038/nrclinonc.2010.224DOI Listing
February 2011

Anti-vascular endothelial growth factor treatment in combination with chemotherapy delays hematopoietic recovery due to decreased proliferation of bone marrow hematopoietic progenitor cells.

J Thorac Oncol 2010 Sep;5(9):1410-5

Division of Hematology/Oncology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University, 220 Pierce Avenue, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1097/JTO.0b013e3181e59c24DOI Listing
September 2010

Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling.

Mol Endocrinol 2010 Mar 4;24(3):644-56. Epub 2010 Feb 4.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1210/me.2009-0357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840807PMC
March 2010

Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients.

Cancer Epidemiol Biomarkers Prev 2010 Feb 19;19(2):358-65. Epub 2010 Jan 19.

Division of Hematology/Oncology, Department of Medicine, Vanderbilt-Ingram Comprehensive Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232-6307, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-09-0937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846615PMC
February 2010

Targeting specific regions of the Notch3 ligand-binding domain induces apoptosis and inhibits tumor growth in lung cancer.

Cancer Res 2010 Jan 12;70(2):632-8. Epub 2010 Jan 12.

Department of Cancer Biology, Division of Hematology and Medical Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210016PMC
January 2010