David Oscier

David Oscier

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David Oscier

David Oscier

Publications by authors named "David Oscier"

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Systematic Review of Somatic Mutations in Splenic Marginal Zone Lymphoma.

Sci Rep 2019 Jul 18;9(1):10444. Epub 2019 Jul 18.

Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.

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http://dx.doi.org/10.1038/s41598-019-46906-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639539PMC
July 2019

A unique genome in EBV-positive BL.

Blood 2019 03;133(12):1269-1270

Royal Bournemouth Hospital.

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http://dx.doi.org/10.1182/blood-2019-01-897603DOI Listing
March 2019

Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation.

Mol Cell Proteomics 2018 04 24;17(4):776-791. Epub 2018 Jan 24.

From the ‡Antibody and Vaccine Group, Cancer Sciences Unit, Faculty of Medicine, General Hospital, University of Southampton, Southampton, UK;

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http://dx.doi.org/10.1074/mcp.RA117.000539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880099PMC
April 2018

Clonal B-cell lymphocytosis of marginal zone origin.

Best Pract Res Clin Haematol 2017 Mar - Jun;30(1-2):77-83. Epub 2016 Nov 4.

Institute of Applied Biosciences, CERTH, Thessaloniki, Greece; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.beha.2016.08.028DOI Listing
October 2017

Type C TP53-CDKN1A pathway dysfunction occurs independently of CDKN1A gene polymorphisms in chronic lymphocytic leukaemia and is associated with TP53 abnormalities.

Br J Haematol 2017 09 13;178(5):824-826. Epub 2016 Jun 13.

Department of Molecular Pathology, Royal Bournemouth Hospital, Bournemouth, Dorset, UK.

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http://dx.doi.org/10.1111/bjh.14172DOI Listing
September 2017

The long-term outcome of patients in the LRF CLL4 trial: the effect of salvage treatment and biological markers in those surviving 10 years.

Br J Haematol 2016 Jan 12;172(2):228-37. Epub 2015 Oct 12.

Division of Molecular Pathology, The Institute of Cancer Research, London, UK.

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http://doi.wiley.com/10.1111/bjh.13824
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http://dx.doi.org/10.1111/bjh.13824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832371PMC
January 2016

Splenic marginal-zone lymphoma: ontogeny and genetics.

Leuk Lymphoma 2015 Feb 19;56(2):301-10. Epub 2014 Aug 19.

Department of Immunology, Genetics and Pathology, Science for Life laboratory, Uppsala University , Uppsala , Sweden.

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http://dx.doi.org/10.3109/10428194.2014.919636DOI Listing
February 2015

Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations.

Blood 2015 Jan 17;125(5):856-9. Epub 2014 Dec 17.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden; Institute of Applied Biosciences, Centre for Research and Technology-Hellas, Thessaloniki, Greece; Hematology Department and Hematopoietic Cell Transplantation Unit, Georgios Papanicolaou Hospital, Thessaloniki, Greece;

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http://www.bloodjournal.org/content/bloodjournal/125/5/856.f
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-09-60
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http://dx.doi.org/10.1182/blood-2014-09-600874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311230PMC
January 2015

Translocation t(2;7)(p11.2;q21.2): a rare genetic aberration associated with B-cell lymphoproliferative disorders of marginal-zone origin.

Cancer Genet 2014 Jun 25;207(6):281-3. Epub 2014 Jun 25.

Institute of Applied Biosciences, CERTH, Thessaloniki, Greece; Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece; Department of Immunology, Genetics & Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2014.06.026DOI Listing
June 2014

Rituximab plus chlorambucil as first-line treatment for chronic lymphocytic leukemia: Final analysis of an open-label phase II study.

J Clin Oncol 2014 Apr 17;32(12):1236-41. Epub 2014 Mar 17.

Peter Hillmen, Abraham Varghese, and Andy Rawstron, St James's Institute of Oncology; Dena Cohen, University of Leeds, Leeds; John G. Gribben, Barts and the London School of Medicine; Claire E. Dearden, Royal Marsden Hospital; Amit Nathwani, University College London, London; George A. Follows, Addenbrooke's Hospital, Cambridge; Donald Milligan, Heartlands Hospital, Birmingham; Hazem A. Sayala, Hull and East Yorkshire Hospitals, Hull; Paul Moreton, Pinderfields General Hospital, Wakefield; David G. Oscier, Royal Bournemouth Hospital, Bournemouth; Daniel B. Kennedy, Leicester Royal Infirmary, Leicester; Andrew R. Pettitt, Royal Liverpool and Broadgreen University Hospitals National Health Service Trust, Liverpool; Christopher F.E. Pocock, East Kent Hospitals, Canterbury, United Kingdom; and Stephan Oertel, F. Hoffmann-La Roche, Basel, Switzerland.

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http://dx.doi.org/10.1200/JCO.2013.49.6547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876343PMC
April 2014

Cross-talk between DNA methylation and active histone modifications regulates aberrant expression of ZAP70 in CLL.

J Cell Mol Med 2012 Sep;16(9):2074-84

Faculty of Medical Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/j.1582-4934.2011.01503.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822977PMC
September 2012

Methylation markers identify high risk patients in IGHV mutated chronic lymphocytic leukemia.

Epigenetics 2011 Mar 1;6(3):300-6. Epub 2011 Mar 1.

Crucible Laboratory, Institute for Ageing and Health, Newcastle University, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092678PMC
http://dx.doi.org/10.4161/epi.6.3.14038DOI Listing
March 2011

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1.

Exp Cell Res 2009 Oct 8;315(17):2941-52. Epub 2009 Jul 8.

Department of Oncology-Pathology, Cancercentrum Karolinska, Karolinska Institutet R8:03, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2009.07.001DOI Listing
October 2009

The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1.

Genes Chromosomes Cancer 2008 May;47(5):379-85

Wessex Regional Genetics Laboratory, Salisbury District Hospital and Human Genetics Division, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1002/gcc.20541DOI Listing
May 2008

Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis.

Blood 2008 Feb 15;111(3):1625-33. Epub 2007 Nov 15.

Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1182/blood-2007-08-110130DOI Listing
February 2008

Cytogenetic aberrations and immunoglobulin VH gene mutations in clinically benign CD5- monoclonal B-cell lymphocytosis.

Am J Clin Pathol 2007 Aug;128(2):333-8

Department of Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1309/WB56ET6AGM44TM5TDOI Listing
August 2007

Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.

Blood 2006 Jul 9;108(1):337-45. Epub 2006 Mar 9.

Leukaemia Research Fund (LRF) Molecular Haematology Unit, Nuffield Department of Clinical Laboratory Sciences (NDCLS), John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1182/blood-2005-12-4769DOI Listing
July 2006

Biology and prognostic factors in CLL.

Authors:
David Oscier

Hematology 2005 ;10 Suppl 1:197-9

Department of Haematology, Royal Bournemouth Hospital, Bournemouth, UK.

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http://dx.doi.org/10.1080/10245330512331390410DOI Listing
June 2006

ZAP-70 in B cell malignancies.

Leuk Lymphoma 2005 Dec;46(12):1689-98

Department of Haematology, Royal Bournemouth Hospital, UK.

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http://dx.doi.org/10.1080/09638280500260079DOI Listing
December 2005

Splenic marginal zone lymphoma: 7q abnormalities.

Methods Mol Med 2005 ;115:241-50

Molecular Biology Department, Royal Bournemouth Hospital, UK.

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http://dx.doi.org/10.1385/1-59259-936-2:241DOI Listing
August 2005

ZAP-70 methylation status is associated with ZAP-70 expression status in chronic lymphocytic leukemia.

Haematologica 2005 Aug;90(8):1078-88

Department of Molecular Biology and Haematology, Royal Bournemouth Hospital, Bournemouth, Dorset, BH7 7DW, UK.

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August 2005