David O Azorsa

David O Azorsa

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David O Azorsa

David O Azorsa

Publications by authors named "David O Azorsa"

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29Publications

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Clinical resistance associated with a novel MAP2K1 mutation in a patient with Langerhans cell histiocytosis.

Pediatr Blood Cancer 2018 09 16;65(9):e27237. Epub 2018 May 16.

Institute of Molecular Medicine, Phoenix Children's Hospital, Phoenix, Arizona.

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http://doi.wiley.com/10.1002/pbc.27237
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http://dx.doi.org/10.1002/pbc.27237DOI Listing
September 2018

Optimization of Transfection Conditions for siRNA Screening.

Methods Mol Biol 2016 ;1470:15-24

Institute of Molecular Medicine, Phoenix Children's Hospital, Phoenix, AZ, USA.

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http://dx.doi.org/10.1007/978-1-4939-6337-9_2DOI Listing
December 2017

Data Analysis for High-Throughput RNAi Screening.

Methods Mol Biol 2016 ;1470:247-60

Constellation Pharmaceuticals, Cambridge, MA, USA.

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http://dx.doi.org/10.1007/978-1-4939-6337-9_19DOI Listing
December 2017

Disulfiram overcomes bortezomib and cytarabine resistance in Down-syndrome-associated acute myeloid leukemia cells.

J Exp Clin Cancer Res 2017 02 1;36(1):22. Epub 2017 Feb 1.

Institute of Molecular Medicine at Phoenix Children's Hospital, Phoenix, AZ, USA.

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http://dx.doi.org/10.1186/s13046-017-0493-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286849PMC
February 2017

Genome scale cytometry: High content analysis for high throughput RNAi phenotype profiling.

Drug Discov Today Technol 2005 ;2(2):141-7

Cancer Drug Development Laboratory, Translational Genomics Research Institute, 20, Firstfield Rd, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1016/j.ddtec.2005.05.012DOI Listing
July 2014

High-throughput RNAi screening for the identification of novel targets.

Methods Mol Biol 2013 ;986:89-95

Clinical Translational Research Division, Translational Genomics Research Institute, Scottsdale, AZ, USA.

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http://dx.doi.org/10.1007/978-1-62703-311-4_6DOI Listing
August 2013

Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.

PLoS One 2012 4;7(10):e46823. Epub 2012 Oct 4.

Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046823PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464231PMC
May 2013

BIRC5 expression is a poor prognostic marker in Ewing sarcoma.

Pediatr Blood Cancer 2013 Jan 7;60(1):35-40. Epub 2012 Sep 7.

Center for Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, AZ 85016, USA.

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http://doi.wiley.com/10.1002/pbc.24290
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http://dx.doi.org/10.1002/pbc.24290DOI Listing
January 2013

The genomic and proteomic content of cancer cell-derived exosomes.

Front Oncol 2012 17;2:38. Epub 2012 Apr 17.

Clinical Translational Research Division, The Translational Genomics Research Institute Scottsdale, AZ, USA.

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http://dx.doi.org/10.3389/fonc.2012.00038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355967PMC
August 2012

RNAi screening of the kinome with cytarabine in leukemias.

Blood 2012 Mar 20;119(12):2863-72. Epub 2012 Jan 20.

Division of Hematology and Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1182/blood-2011-07-367557DOI Listing
March 2012

High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells.

Mol Cancer Res 2011 Jun 2;9(6):724-32. Epub 2011 May 2.

Clinical Translational Research Division, Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-10-0436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137903PMC
June 2011

RNAi screening of the kinome identifies modulators of cisplatin response in ovarian cancer cells.

Gynecol Oncol 2010 Sep;118(3):220-7

Pharmaceutical Genomics Division, The Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1016/j.ygyno.2010.05.006DOI Listing
September 2010

Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer.

Cancer Res 2010 Aug 27;70(16):6497-508. Epub 2010 Jul 27.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Human Genome Research Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922412PMC
August 2010

RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma.

Mol Cancer 2010 Aug 18;9:218. Epub 2010 Aug 18.

Pharmaceutical Genomic Division, Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1186/1476-4598-9-218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933621PMC
August 2010

A high-content RNAi-screening assay to identify modulators of cholesterol accumulation in Niemann-Pick type C cells.

Assay Drug Dev Technol 2010 Jun;8(3):295-320

Pharmaceutical Genomics Division, The Translational Genomics Research Institute, Scottsdale, Arizona, USA.

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http://dx.doi.org/10.1089/adt.2009.0240DOI Listing
June 2010

Chemogenomic analysis identifies Macbecin II as a compound specific for SMAD4-negative colon cancer cells.

Chem Biol Drug Des 2010 Apr;75(4):360-8

Pharmaceutical Genomics Division, The Translational Genomics Research Institute, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1111/j.1747-0285.2010.00949.xDOI Listing
April 2010

Functional evidence implicating S100P in prostate cancer progression.

Int J Cancer 2008 Jul;123(2):330-339

Pharmaceutical Genomics Division, The Translational Genomics Research Institute, Scottsdale, AZ.

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http://dx.doi.org/10.1002/ijc.23447DOI Listing
July 2008

Intersex-like (IXL) is a cell survival regulator in pancreatic cancer with 19q13 amplification.

Cancer Res 2007 Mar;67(5):1943-9

Laboratory of Cancer Genetics, Institute of Medical Technology, University of Tampere and Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3387DOI Listing
March 2007

Phenotypic alterations in breast cancer cells overexpressing the nuclear receptor co-activator AIB1.

BMC Cancer 2003 Sep 10;3:22. Epub 2003 Sep 10.

Cancer Genetics Branch, NHGRI, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1186/1471-2407-3-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC201023PMC
September 2003