David N Louis

David N Louis

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An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.

Cell 2019 Aug 18;178(4):835-849.e21. Epub 2019 Jul 18.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703186PMC
August 2019

cIMPACT-NOW: a practical summary of diagnostic points from Round 1 updates.

Brain Pathol 2019 07 22;29(4):469-472. Epub 2019 May 22.

Department of Pathology, Amsterdam University Medical Centers/VUmc, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bpa.12732DOI Listing
July 2019

A half century of change in diagnostic neuropathology: from the giants of yore to current brain tumor classification.

Authors:
David N Louis

Hum Pathol 2019 Jul 11. Epub 2019 Jul 11.

James Homer Wright Pathology Laboratories, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2019.06.006DOI Listing
July 2019

Characterization of applicants for residency training in pathology: Does diversity exist?

Ann Diagn Pathol 2019 Jun 10;40:23-25. Epub 2019 Feb 10.

Harvard Medical School, Boston, MA, USA; Pathology Service, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.anndiagpath.2019.02.010DOI Listing
June 2019

Data Sets for the Reporting of Tumors of the Central Nervous System.

Arch Pathol Lab Med 2019 Jun 20. Epub 2019 Jun 20.

From the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (Dr Louis); the Department of Pathology, Amsterdam Universities Medical Center/VUmc CCA Brain Tumor Center, Amsterdam, the Netherlands (Dr Wesseling); the Department of Pathology, Princess Máxima Center for Pediatric Oncology, and University Medical Center Utrecht, Utrecht, the Netherlands (Dr Wesseling); Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, United Kingdom (Dr Brandner); the Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom (Dr Brandner); the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr Brat); the Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee (Dr Ellison); the Department of Radiology, Oncology and Anatomic Pathology, University La Sapienza, Rome, Italy (Dr Giangaspero); IRCCS Neuromed, Pozzilli, Isernia, Italy (Dr Giangaspero); the Department of Pathology, University of Louisville School of Medicine, Louisville, Kentucky (Dr Hattab); the Department of Laboratory Medicine & Pathobiology, The Hospital for Sick Children, Toronto, Ontario, Canada (Dr Hawkins); Project Management Office, Royal College of Pathologists of Australasia, Sydney, Australia (Ms Judge); the Departments of Pathology, Neurology, and Neurosurgery, University of Colorado, Aurora (Dr Kleinschmidt-DeMasters); the Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo, Japan (Dr Komori); the Department of Pathology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan (Dr Komori); Alfred Anatomical Pathology and NNF, Victorian Brain Bank, Carlton, Victoria, Australia (Dr McLean); Institute of Neuropathology, University Hospital Münster, Münster, Germany (Dr Paulus); Division of Neuropathology, Department of Pathology, University of California, San Francisco (Dr Perry); the Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany (Dr Reifenberger); German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Düsseldorf, Germany (Dr Reifenberger); the Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland (Dr Weller); and the Department of Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom (Dr Rous); ICCR Steering Group Representative (Dr Rous).

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http://dx.doi.org/10.5858/arpa.2018-0565-OADOI Listing
June 2019

cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAF mutation.

Acta Neuropathol 2019 Apr 8;137(4):683-687. Epub 2019 Mar 8.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00401-019-01987-0DOI Listing
April 2019

Localized crystal-storing histiocytosis of the posterior fossa.

Neuropathology 2018 Oct 31;38(5):529-534. Epub 2018 Jul 31.

Department of Pathology, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1111/neup.12486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172157PMC
October 2018

A feast of reviews about brain and pituitary tumor pathology.

Authors:
David N Louis

Brain Tumor Pathol 2018 Apr;35(2):49-50

Massachusetts General Hospital and Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1007/s10014-018-0315-2DOI Listing
April 2018

cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC).

Acta Neuropathol 2018 03 25;135(3):481-484. Epub 2018 Jan 25.

The Brain Tumor Center at Erasmus MC Cancer Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-018-1808-0DOI Listing
March 2018

Grading of Diffuse Astrocytic Gliomas: A Review of Studies Before and After the Advent of IDH Testing.

Semin Neurol 2018 02 16;38(1):19-23. Epub 2018 Mar 16.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1055/s-0038-1636430DOI Listing
February 2018

The 2016 WHO classification of central nervous system tumors: what neurologists need to know.

Curr Opin Neurol 2017 Dec;30(6):643-649

aDepartment of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA bDivision of Experimental Neurosurgery, Department of Neurosurgery cDepartment of Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1097/WCO.0000000000000490DOI Listing
December 2017

Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations.

Neuro Oncol 2017 Nov;19(12):1640-1650

Department of Pathology; Department of Neurology, Division of Neuro-Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/neuonc/nox120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716163PMC
November 2017

Multicenter phase II study of temozolomide and myeloablative chemotherapy with autologous stem cell transplant for newly diagnosed anaplastic oligodendroglioma.

Neuro Oncol 2017 Oct;19(10):1380-1390

Memorial Sloan Kettering Cancer Center, New York, New York,USA; Northwestern Memorial Hospital, Chicago, Illinois, USA; NorthShore University, Evanston, Illinois,USA; University of Calgary, Calgary, Alberta, Canada; Massachusetts General Hospital, Boston, Massachusetts, USA; MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1093/neuonc/nox086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596171PMC
October 2017

Grading of diffuse astrocytic gliomas: Broders, Kernohan, Zülch, the WHO… and Shakespeare.

Acta Neuropathol 2017 10 11;134(4):517-520. Epub 2017 Aug 11.

Department of Neuropathology, Institute of Pathology, Ruprecht-Karls-University, Heidelberg, Germany.

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http://link.springer.com/10.1007/s00401-017-1765-z
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http://dx.doi.org/10.1007/s00401-017-1765-zDOI Listing
October 2017

Correction.

J Radiol Case Rep 2017 Oct 31;11(10). Epub 2017 Oct 31.

Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.3941/jrcr.v11i10.3328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741321PMC
October 2017

Integrating molecular markers into the World Health Organization classification of CNS tumors: a survey of the neuro-oncology community.

Neuro Oncol 2017 03;19(3):336-344

MacFeeters-Hamilton Brain Tumour Centre, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/neuonc/now181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464323PMC
March 2017

Examining Neuropathology: Beginning a Dialogue.

J Neuropathol Exp Neurol 2016 12;75(12):1179-1183

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http://dx.doi.org/10.1093/jnen/nlw091DOI Listing
December 2016

Case 38-2016. A 52-Year-Old Woman with Recurrent Oligodendroglioma.

N Engl J Med 2016 12;375(24):2381-2389

From the Departments of Neurology (A.S.C.), Neurosurgery (D.P.C.), Radiology (M.L.), and Pathology (D.N.L.), Massachusetts General Hospital, and the Departments of Neurology (A.S.C.), Neurosurgery (D.P.C.), Radiology (M.L.), and Pathology (D.N.L.), Harvard Medical School - both in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1610101DOI Listing
December 2016

Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying).

J Neurooncol 2016 10 14;130(1):31-42. Epub 2016 Jul 14.

Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Wearn 152, Cleveland, OH, 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071143PMC
http://dx.doi.org/10.1007/s11060-016-2217-7DOI Listing
October 2016

Impact of histopathological transformation and overall survival in patients with progressive anaplastic glioma.

J Clin Neurosci 2016 Sep 6;31:99-105. Epub 2016 Jun 6.

Stephen E. and Catherine Pappas Center for Neuro-Oncology and Division of Hematology/Oncology, Department of Neurology, Massachusetts General Hospital Cancer Center, 55 Fruit Street/Y9E, Boston, MA 02114, USA; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S096758681600123
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http://dx.doi.org/10.1016/j.jocn.2016.02.019DOI Listing
September 2016

The flowering of pathology as a medical discipline in Boston, 1892-c.1950: W.T. Councilman, FB Mallory, JH Wright, SB Wolbach and their descendants.

Mod Pathol 2016 09 17;29(9):944-61. Epub 2016 Jun 17.

James Homer Wright Pathology Laboratories, Pathology Service, Massachusetts General Hospital and Department of Pathology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2016.91DOI Listing
September 2016

Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.

CNS Oncol 2015 6;4(5):287-94. Epub 2015 Nov 6.

Southern Alberta Cancer Research Institute, University of Calgary, Calgary, AB T2N 1N4, Canada.

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http://dx.doi.org/10.2217/cns.15.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082339PMC
August 2016

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Acta Neuropathol 2016 06 9;131(6):803-20. Epub 2016 May 9.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1007/s00401-016-1545-1DOI Listing
June 2016

Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy.

J Natl Cancer Inst 2016 Feb 23;108(2). Epub 2015 Oct 23.

Department of Medicine (PKB, RS), Department of Neurology (PKB, CMG), Department of Neurosurgery (GMS, PJ, BN, DPC, WTC, FGB), Department of Surgical Oncology (DTF), Department of Pathology (GG, DNL), Cancer Center (PKB, CMG, NN, DNL), Department of Radiology (JR) Massachusetts General Hospital, Harvard Medical School, Boston, MA; Broad Institute (ATW, GG), Department of Pathology, (MA, SS) and Department of Neurosurgery, Brigham and Women's Hospital (IFD), Boston, MA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (DJP).

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http://dx.doi.org/10.1093/jnci/djv310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862417PMC
February 2016

Computational Pathology: A Path Ahead.

Arch Pathol Lab Med 2016 Jan 22;140(1):41-50. Epub 2015 Jun 22.

From the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston (Drs Louis, Dighe, and Gilbertson); the Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (Dr Feldman); the Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia (Dr Carter); the Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri (Dr Pfeifer); the Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts (Drs Bry, Gerber, and Golden); the Department of Biomedical Informatics, Stony Brook University, Stony Brook, New York (Drs Almeida and Saltz); the Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles (Dr Braun); the Department of Pathology and Anatomical Science, State University of New York at Buffalo (Dr Tomaszewski); the Department of Pathology, Yale Medical School, New Haven, Connecticut (Dr Sinard); the Department of Pathology and Laboratory Medicine, Stanford University, Palo Alto, California (Dr Galli); and the Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania (Dr Becich).

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http://dx.doi.org/10.5858/arpa.2015-0093-SADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996078PMC
January 2016

Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment.

J Neuropathol Exp Neurol 2015 Jul;74(7):710-22

From the Department of Neurosurgery (FN, JC, APP, WTC, SE, RLM, SDR, HW), and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts (EMK); Division of Hematology/Oncology, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Department of Neurology (ASC), Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (DNL).

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https://academic.oup.com/jnen/article-lookup/doi/10.1097/NEN
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http://dx.doi.org/10.1097/NEN.0000000000000210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473779PMC
July 2015

Cross-reactivity of the BRAF VE1 antibody with epitopes in axonemal dyneins leads to staining of cilia.

Mod Pathol 2015 Apr 21;28(4):596-606. Epub 2014 Nov 21.

1] Division of Neuropathology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA [2] Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/modpathol2014150
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http://dx.doi.org/10.1038/modpathol.2014.150DOI Listing
April 2015

Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors.

Neuro Oncol 2014 Nov 4;16(11):1541-6. Epub 2014 Jul 4.

Departments of Neurology (A.B.L., F.M.I., L.E.A., L.M.D.), Pathology (S.C.J., M.K.R.), Epidemiology & Biostatistics (A.S.R., K.S.P.), and the Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York; University of California, Los Angeles, Los Angeles, California (T.F.C.); Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas (K.D.A., A.L.R.); Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (A.F.E., D.N.L.); NorthShore University Health System, Evanston Hospital Kellogg Cancer Center, University of Chicago, Pritzker School of Medicine, Evanston, Illinois (N.A.P.); London Regional Cancer Program, London, Ontario, Canada (B.J.F.); Barrow Neurological Institute, Phoenix, Arizona (L.S.A.); University of Calgary, Calgary, Alberta, Canada (J.G.C., G.B.R.U.); Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts (P.Y.W.); Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Children's Hospital Boston, Brigham and Women's Hospital, Boston, Massachusetts (K.L.L.); University of Virginia Health System, Charlottesville, Virginia (D.S.); University of Wisconsin, Madison, Wisconsin (H.I.R., B.G.R.); University of Washington, Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance, Seattle, Washington (M.C.C.); Princess Margaret Hospital, Toronto, Ontario, Canada (W.P.M.); Albany Medical Center, Albany, New York (S.A.W.); Kaiser Permanente-Los Angeles Medical Center, Los Angeles, California (R.M.G.); Clemenceau Medical Center, Beirut, Lebanon and Université Saint-Esprit de Kaslik, Byblos, Lebanon (F.G.K.).

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http://dx.doi.org/10.1093/neuonc/nou083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201067PMC
November 2014

Brain tumor cells in circulation are enriched for mesenchymal gene expression.

Cancer Discov 2014 Nov 19;4(11):1299-309. Epub 2014 Aug 19.

Massachusetts General Hospital Cancer Center, Boston, Massachusetts. Department of Medicine, Harvard Medical School, Boston, Massachusetts. Howard Hughes Medical Institute, Chevy Chase, Maryland.

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http://dx.doi.org/10.1158/2159-8290.CD-14-0471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221467PMC
November 2014

Computational pathology: an emerging definition.

Arch Pathol Lab Med 2014 Sep;138(9):1133-8

From the Partners Program in Computational Pathology and the Department of Pathology, Massachusetts General Hospital, Boston (Drs Louis, Baron, Dighe, Getz, Higgins, Michaelson, Le, Mermel, and Gilbertson); the Department of Pathology, Brigham and Women's Hospital, Boston (Drs Gerber, Bry, Kuo, Lane, and Golden); the Departments of Pathology (Drs Louis, Gerber, Baron, Bry, Dighe, Getz, Kuo, Lane, Michaelson, Le, Mermel, Gilbertson, and Golden) and Systems Biology (Dr Higgins), Harvard Medical School, Boston; and the Broad Institute, Cambridge, Massachusetts (Drs Getz, Le, and Mermel). Drs Louis, Gilbertson, and Golden are co-senior authors.

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http://www.archivesofpathology.org/doi/abs/10.5858/arpa.2014
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http://dx.doi.org/10.5858/arpa.2014-0034-EDDOI Listing
September 2014

VE1 antibody immunoreactivity in normal anterior pituitary and adrenal cortex without detectable BRAF V600E mutations.

Am J Clin Pathol 2014 Jun;141(6):811-5

From the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1309/AJCP37TLZLTUAOJLDOI Listing
June 2014

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.

Science 2014 Jun 12;344(6190):1396-401. Epub 2014 Jun 12.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. Broad Institute of Harvard and Massachusetts Institute of Techonology (MIT), Cambridge, MA 02142, USA. Howard Hughes Medical Institute Chevy Chase, MD 20815, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1254257
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http://dx.doi.org/10.1126/science.1254257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123637PMC
June 2014

Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells.

Cell 2014 Apr 10;157(3):580-94. Epub 2014 Apr 10.

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.02.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004670PMC
April 2014

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.

Nat Genet 2014 Feb 12;46(2):161-5. Epub 2014 Jan 12.

1] Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Pathology, Boston Children's Hospital, Boston, Massachusetts, USA. [3] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA. [4] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.2868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982316PMC
February 2014

Next-generation molecular genetics of brain tumours.

Curr Opin Neurol 2013 Dec;26(6):681-7

aDepartment of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston bBroad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1097/WCO.0000000000000027DOI Listing
December 2013

Refined brain tumor diagnostics and stratified therapies: the requirement for a multidisciplinary approach.

Acta Neuropathol 2013 Jul 21;126(1):21-37. Epub 2013 May 21.

Department of Neuropathology, Regensburg University Hospital, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1007/s00401-013-1127-4DOI Listing
July 2013

BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults.

J Clin Oncol 2013 May 1;31(14):e233-6. Epub 2013 Apr 1.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2012.46.0220DOI Listing
May 2013

An ultra-high speed Whole Slide Image viewing system.

Stud Health Technol Inform 2012 ;179:239-49

Pathology Service, Massachusetts General Hospital, Boston, MA, USA.

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https://dash.harvard.edu/bitstream/handle/1/23993570/4605572
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January 2013

Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?

Nat Rev Clin Oncol 2013 Jan 27;10(1):14-26. Epub 2012 Nov 27.

Stephen E. and Catherine Pappas Center for Neuro-Oncology, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/nrclinonc.2012.204DOI Listing
January 2013

Prospective, high-throughput molecular profiling of human gliomas.

J Neurooncol 2012 Oct 22;110(1):89-98. Epub 2012 Jul 22.

Department of Neurology, Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA.

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http://dx.doi.org/10.1007/s11060-012-0938-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583376PMC
October 2012

Case records of the Massachusetts General Hospital. Case 17-2012. A 54-year-old man with visual-field loss and a mass in the brain.

N Engl J Med 2012 May;366(22):2112-20

Department of Neurology, Massachusetts General Hospital, Boston, USA.

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http://dx.doi.org/10.1056/NEJMcpc1111574DOI Listing
May 2012

A tell-tail sign of chromatin: histone mutations drive pediatric glioblastoma.

Cancer Cell 2012 Mar;21(3):329-31

Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.03.001DOI Listing
March 2012

Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.

J Natl Cancer Inst 2012 Jan 15;104(1):42-55. Epub 2011 Dec 15.

Brain Tumor Research Center, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114 , USA.

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http://dx.doi.org/10.1093/jnci/djr509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250384PMC
January 2012

"Next-generation" pathology and laboratory medicine.

Arch Pathol Lab Med 2011 Dec;135(12):1531-2

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http://dx.doi.org/10.5858/arpa.2011-0414-EDDOI Listing
December 2011

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

Cancer Cell 2011 Dec 1;20(6):810-7. Epub 2011 Dec 1.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.11.005DOI Listing
December 2011

The Warrens and other pioneering clinician pathologists of the Massachusetts General Hospital during its early years: an appreciation on the 200th anniversary of the hospital founding.

Mod Pathol 2011 Oct 16;24(10):1285-94. Epub 2011 Sep 16.

The James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2011.132DOI Listing
October 2011

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications.

PLoS One 2011 Mar 29;6(3):e17948. Epub 2011 Mar 29.

Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017948PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066220PMC
March 2011

Assessing Population Level Genetic Instability via Moving Average.

Stat Biosci 2010 Dec 24;2(2):120-136. Epub 2010 Nov 24.

Department of Mathematics, The University of the West Indies, Mona, Jamaica.

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http://dx.doi.org/10.1007/s12561-010-9028-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409593PMC
December 2010

Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers.

Lancet Neurol 2010 Jul;9(7):717-26

Pathology Service, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/S1474-4422(10)70105-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079431PMC
July 2010

Application of signal processing techniques for estimating regions of copy number variations in human meningioma DNA.

Conf Proc IEEE Eng Med Biol Soc 2009 ;2009:6973-6

Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

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http://dx.doi.org/10.1109/IEMBS.2009.5333851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796201PMC
April 2010

Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression.

Cancer Res 2010 Mar 23;70(6):2350-8. Epub 2010 Feb 23.

Neuroendocrine Unit and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987571PMC
March 2010