David Meyre

David Meyre

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David Meyre

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Benefits and limitations of genome-wide association studies.

Nat Rev Genet 2019 Aug;20(8):467-484

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/s41576-019-0127-1DOI Listing
August 2019

Loss-of-function mutations in the melanocortin-3 receptor gene confer risk for human obesity: A systematic review and meta-analysis.

Obes Rev 2019 Aug 14;20(8):1085-1092. Epub 2019 May 14.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1111/obr.12864DOI Listing
August 2019

A Candidate-Gene Approach Identifies Novel Associations Between Common Variants in/Near Syndromic Obesity Genes and BMI in Pediatric and Adult European Populations.

Diabetes 2019 Apr 28;68(4):724-732. Epub 2019 Jan 28.

Department of Health Research, Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada

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http://dx.doi.org/10.2337/db18-0986DOI Listing
April 2019

Comprehensive identification of pleiotropic loci for body fat distribution using the NHGRI-EBI Catalog of published genome-wide association studies.

Obes Rev 2019 03 22;20(3):385-406. Epub 2018 Nov 22.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1111/obr.12806DOI Listing
March 2019

An Evolutionary Genetic Perspective of Eating Disorders.

Neuroendocrinology 2018 24;106(3):292-306. Epub 2017 Oct 24.

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http://dx.doi.org/10.1159/000484525DOI Listing
January 2019

Fine-mapping of 98 obesity loci in Mexican children.

Int J Obes (Lond) 2019 01 12;43(1):23-32. Epub 2018 Mar 12.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1038/s41366-018-0056-7DOI Listing
January 2019

Genetic contribution to waist-to-hip ratio in Mexican children and adolescents based on 12 loci validated in European adults.

Int J Obes (Lond) 2019 01 13;43(1):13-22. Epub 2018 Mar 13.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.

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http://dx.doi.org/10.1038/s41366-018-0055-8DOI Listing
January 2019

Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity.

Clin Nutr 2018 10 24;37(5):1700-1706. Epub 2017 Jul 24.

Inserm UMRS 954 N-GERE (Nutrition-Genetics-Environmental Risks), University de Lorraine, Faculty of Medicine, Nancy, France; Department of Digestive, Hepato-Biliary and Endocrine Surgery, Regional University Hospital of Nancy (CHRU Nancy), Nancy, France; Unité Multidisciplinaire de la chirurgie de l'obésité (UMCO), Regional University Hospital of Nancy (CHRU Nancy), Nancy, France. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2017.07.008DOI Listing
October 2018

Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease.

J Am Coll Cardiol 2018 07 9;72(3):300-310. Epub 2018 Jul 9.

Population Health Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada; Thrombosis and Atherosclerosis Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada; Department of Pathology and Molecular Medicine, McMaster University, Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183483
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http://dx.doi.org/10.1016/j.jacc.2018.04.067DOI Listing
July 2018

The Extending Spectrum of NPC1-Related Human Disorders: From Niemann-Pick C1 Disease to Obesity.

Endocr Rev 2018 04;39(2):192-220

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1210/er.2017-00176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888214PMC
April 2018

Fine-mapping of 98 obesity loci in Mexican children.

Int J Obes (Lond) 2019 01 12;43(1):23-32. Epub 2018 Mar 12.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1038/s41366-018-0056-7DOI Listing
January 2019

Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution.

Am J Hum Genet 2017 Dec;101(6):925-938

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON L8S 4L8, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON L8S 4L8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812888PMC
December 2017

Give GWAS a Chance.

Authors:
David Meyre

Diabetes 2017 11;66(11):2741-2742

Department of Health Research Methods, Evidence, and Impact and Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada

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http://dx.doi.org/10.2337/dbi17-0026DOI Listing
November 2017

Helicobacter pylori colonization and obesity - a Mendelian randomization study.

Sci Rep 2017 10 31;7(1):14467. Epub 2017 Oct 31.

Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-14106-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663904PMC
October 2017

Physical Activity and Global Self-worth in a Longitudinal Study of Children.

Med Sci Sports Exerc 2017 08;49(8):1606-1613

1Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, CANADA; 2Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, CANADA; 3Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, CANADA; and 4Infant and Child Health (INCH) Research Lab, Department of Family Medicine, McMaster University, Hamilton, ON, CANADA.

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http://dx.doi.org/10.1249/MSS.0000000000001275DOI Listing
August 2017

Assessing the Heritability of Complex Traits in Humans: Methodological Challenges and Opportunities.

Curr Genomics 2017 Aug;18(4):332-340

Department of Health Research Methods, McMaster University, Evidence and Impact, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.2174/1389202918666170307161450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635617PMC
August 2017

Influence of depression on genetic predisposition to type 2 diabetes in a multiethnic longitudinal study.

Sci Rep 2017 05 9;7(1):1629. Epub 2017 May 9.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/s41598-017-01406-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431642PMC
May 2017

A genetic link between prepregnancy body mass index, postpartum weight retention, and offspring weight in early childhood.

Obesity (Silver Spring) 2017 01 24;25(1):236-243. Epub 2016 Nov 24.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1002/oby.21707DOI Listing
January 2017

Common variants in CACNA1C and MDD susceptibility: A comprehensive meta-analysis.

Am J Med Genet B Neuropsychiatr Genet 2016 09 3;171(6):896-903. Epub 2016 Jun 3.

National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1002/ajmg.b.32466DOI Listing
September 2016

Assessing the effects of 35 European-derived BMI-associated SNPs in Mexican children.

Obesity (Silver Spring) 2016 09 3;24(9):1989-95. Epub 2016 Aug 3.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1002/oby.21590DOI Listing
September 2016

The importance of gene-environment interactions in human obesity.

Clin Sci (Lond) 2016 09;130(18):1571-97

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada L8N 3Z5 Inserm U-954, Faculté de Médecine, University of Lorraine and University Hospital Center of Nancy, Nancy 54052, France Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada L8N 3Z5

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http://dx.doi.org/10.1042/CS20160221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381863PMC
September 2016

Eating Behavior, Low-Frequency Functional Mutations in the Melanocortin-4 Receptor (MC4R) Gene, and Outcomes of Bariatric Operations: A 6-Year Prospective Study.

Diabetes Care 2016 Aug 23;39(8):1384-92. Epub 2016 May 23.

Scientific Computing Center and Departments of Surgery, Medicine, and Cell Biology, SUNY Downstate Medical Center, Brooklyn, NY

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http://dx.doi.org/10.2337/dc16-0115DOI Listing
August 2016

Genetic markers of inflammation may not contribute to metabolic traits in Mexican children.

PeerJ 2016 23;4:e2090. Epub 2016 Jun 23.

Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.7717/peerj.2090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924140PMC
July 2016

Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity.

Clin Sci (Lond) 2016 06;130(12):943-86

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, L8S 4L8, Canada Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, L8S 4L8, Canada

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http://www.clinsci.org/content/ppclinsci/130/12/943.full.pdf
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http://clinsci.org/cgi/doi/10.1042/CS20160136
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http://dx.doi.org/10.1042/CS20160136DOI Listing
June 2016

A systematic review and meta-analysis of nut consumption and incident risk of CVD and all-cause mortality.

Br J Nutr 2016 Jan 9;115(2):212-25. Epub 2015 Nov 9.

1Department of Clinical Epidemiology and Biostatistics,McMaster University,Hamilton, ON,Canada, L8N 3Z5.

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http://dx.doi.org/10.1017/S0007114515004316DOI Listing
January 2016

Physical activity and genetic predisposition to obesity in a multiethnic longitudinal study.

Sci Rep 2016 Jan 4;6:18672. Epub 2016 Jan 4.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/srep18672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698633PMC
January 2016

Obesity genes and risk of major depressive disorder in a multiethnic population: a cross-sectional study.

J Clin Psychiatry 2015 Dec;76(12):e1611-8

Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton General Hospital, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.4088/JCP.14m09720DOI Listing
December 2015

Comment on: Valette et al. Melanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery. PLOS ONE 2012; 7(11):E48221.

PLoS One 2014 31;9(3):e93324. Epub 2014 Mar 31.

Department of Surgery, State University of New York Downstate Medical Center, Brooklyn, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093324PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970954PMC
June 2015

Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.

Hum Mol Genet 2015 Jun 17;24(12):3582-94. Epub 2015 Mar 17.

Department of Clinical Epidemiology and Biostatistics, Divisions of Genetics and Endocrinology, Children's Hospital, Boston, MA 02115, USA, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA,

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http://hmg.oxfordjournals.org/content/early/2015/04/02/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddv097
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http://dx.doi.org/10.1093/hmg/ddv097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498155PMC
June 2015

From big data analysis to personalized medicine for all: challenges and opportunities.

BMC Med Genomics 2015 Jun 27;8:33. Epub 2015 Jun 27.

Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, ON, Canada.

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http://dx.doi.org/10.1186/s12920-015-0108-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482045PMC
June 2015

Re: "The Association of Common Variants in PCSK1 With Obesity: A HuGE Review and Meta-Analysis".

Authors:
David Meyre

Am J Epidemiol 2015 May 9;181(9):732-3. Epub 2015 Apr 9.

Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1093/aje/kwv063DOI Listing
May 2015

Assessing the quality of published genetic association studies in meta-analyses: the quality of genetic studies (Q-Genie) tool.

BMC Genet 2015 May 15;16:50. Epub 2015 May 15.

Population Genomics Program, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1186/s12863-015-0211-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431044PMC
May 2015

Obesity genetics in mouse and human: back and forth, and back again.

PeerJ 2015 24;3:e856. Epub 2015 Mar 24.

Department of Clinical Epidemiology and Biostatistics, McMaster University , Hamilton, ON , Canada ; Department of Pathology and Molecular Medicine, McMaster University , Hamilton, ON , Canada.

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http://dx.doi.org/10.7717/peerj.856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375971PMC
March 2015

Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts.

Diabetologia 2015 Jan 8;58(1):87-97. Epub 2014 Oct 8.

Department of Clinical Epidemiology and Biostatistics, McMaster University, Michael DeGroote Centre for Learning & Discovery, Room 3205, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada.

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http://link.springer.com/content/pdf/10.1007%2Fs00125-014-33
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http://link.springer.com/10.1007/s00125-014-3390-x
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http://dx.doi.org/10.1007/s00125-014-3390-xDOI Listing
January 2015

Identification of two novel loss-of-function SIM1 mutations in two overweight children with developmental delay.

Obesity (Silver Spring) 2014 Dec 19;22(12):2621-4. Epub 2014 Sep 19.

European Genomic Institute for Diabetes, Lille, France. Correspondence: Philippe Froguel CNRS-UMR8199, Lille Pasteur Institute, Lille, France; Lille 2 University, Lille, France; Department of Pediatrics, Saint Antoine Pediatric Hospital, Saint Vincent de Paul Hospital, Catholic University of Lille, Lille, France.

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http://dx.doi.org/10.1002/oby.20886DOI Listing
December 2014

Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?

Diabetologia 2014 Nov 22;57(11):2270-81. Epub 2014 Aug 22.

Population Genomics Program, Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main St W, Hamilton, ON, Canada, L8S 4L8.

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http://dx.doi.org/10.1007/s00125-014-3354-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180911PMC
November 2014

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.

Diabetes 2014 Jun 2;63(6):2158-71. Epub 2013 Dec 2.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, U.K.Department of Genomics of Common Disease, Imperial College London, London, U.K.

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http://dx.doi.org/10.2337/db13-0949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030103PMC
June 2014

Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 1. Fundamental Concepts in Molecular Genetics.

Curr Psychiatry Rev 2014 May;10(2):91-100

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON L8N 3Z5, Canada.

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http://dx.doi.org/10.2174/1573400510666140319234955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133961PMC
May 2014

Jumping on the Train of Personalized Medicine: A Primer for Non-Geneticist Clinicians: Part 2. Fundamental Concepts in Genetic Epidemiology.

Curr Psychiatry Rev 2014 May;10(2):101-117

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON L8N 3Z5, Canada.

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http://dx.doi.org/10.2174/1573400510666140319235334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287874PMC
May 2014

Jumping on the Train of Personalized Medicine: A Primer for Non- Geneticist Clinicians: Part 3. Clinical Applications in the Personalized Medicine Area.

Curr Psychiatry Rev 2014 May;10(2):118-132

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON L8N 3Z5, Canada.

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http://dx.doi.org/10.2174/1573400510666140630170549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287884PMC
May 2014

Genetic dissection of diabetes: facing the giant.

Diabetes 2013 Oct;62(10):3338-40

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.2337/db13-1154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781438PMC
October 2013

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

Authors:
Sonja I Berndt Stefan Gustafsson Reedik Mägi Andrea Ganna Eleanor Wheeler Mary F Feitosa Anne E Justice Keri L Monda Damien C Croteau-Chonka Felix R Day Tõnu Esko Tove Fall Teresa Ferreira Davide Gentilini Anne U Jackson Jian'an Luan Joshua C Randall Sailaja Vedantam Cristen J Willer Thomas W Winkler Andrew R Wood Tsegaselassie Workalemahu Yi-Juan Hu Sang Hong Lee Liming Liang Dan-Yu Lin Josine L Min Benjamin M Neale Gudmar Thorleifsson Jian Yang Eva Albrecht Najaf Amin Jennifer L Bragg-Gresham Gemma Cadby Martin den Heijer Niina Eklund Krista Fischer Anuj Goel Jouke-Jan Hottenga Jennifer E Huffman Ivonne Jarick Åsa Johansson Toby Johnson Stavroula Kanoni Marcus E Kleber Inke R König Kati Kristiansson Zoltán Kutalik Claudia Lamina Cecile Lecoeur Guo Li Massimo Mangino Wendy L McArdle Carolina Medina-Gomez Martina Müller-Nurasyid Julius S Ngwa Ilja M Nolte Lavinia Paternoster Sonali Pechlivanis Markus Perola Marjolein J Peters Michael Preuss Lynda M Rose Jianxin Shi Dmitry Shungin Albert Vernon Smith Rona J Strawbridge Ida Surakka Alexander Teumer Mieke D Trip Jonathan Tyrer Jana V Van Vliet-Ostaptchouk Liesbeth Vandenput Lindsay L Waite Jing Hua Zhao Devin Absher Folkert W Asselbergs Mustafa Atalay Antony P Attwood Anthony J Balmforth Hanneke Basart John Beilby Lori L Bonnycastle Paolo Brambilla Marcel Bruinenberg Harry Campbell Daniel I Chasman Peter S Chines Francis S Collins John M Connell William O Cookson Ulf de Faire Femmie de Vegt Mariano Dei Maria Dimitriou Sarah Edkins Karol Estrada David M Evans Martin Farrall Marco M Ferrario Jean Ferrières Lude Franke Francesca Frau Pablo V Gejman Harald Grallert Henrik Grönberg Vilmundur Gudnason Alistair S Hall Per Hall Anna-Liisa Hartikainen Caroline Hayward Nancy L Heard-Costa Andrew C Heath Johannes Hebebrand Georg Homuth Frank B Hu Sarah E Hunt Elina Hyppönen Carlos Iribarren Kevin B Jacobs John-Olov Jansson Antti Jula Mika Kähönen Sekar Kathiresan Frank Kee Kay-Tee Khaw Mika Kivimäki Wolfgang Koenig Aldi T Kraja Meena Kumari Kari Kuulasmaa Johanna Kuusisto Jaana H Laitinen Timo A Lakka Claudia Langenberg Lenore J Launer Lars Lind Jaana Lindström Jianjun Liu Antonio Liuzzi Marja-Liisa Lokki Mattias Lorentzon Pamela A Madden Patrik K Magnusson Paolo Manunta Diana Marek Winfried März Irene Mateo Leach Barbara McKnight Sarah E Medland Evelin Mihailov Lili Milani Grant W Montgomery Vincent Mooser Thomas W Mühleisen Patricia B Munroe Arthur W Musk Narisu Narisu Gerjan Navis George Nicholson Ellen A Nohr Ken K Ong Ben A Oostra Colin N A Palmer Aarno Palotie John F Peden Nancy Pedersen Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Inga Prokopenko Carolin Pütter Aparna Radhakrishnan Olli Raitakari Augusto Rendon Fernando Rivadeneira Igor Rudan Timo E Saaristo Jennifer G Sambrook Alan R Sanders Serena Sanna Jouko Saramies Sabine Schipf Stefan Schreiber Heribert Schunkert So-Youn Shin Stefano Signorini Juha Sinisalo Boris Skrobek Nicole Soranzo Alena Stančáková Klaus Stark Jonathan C Stephens Kathleen Stirrups Ronald P Stolk Michael Stumvoll Amy J Swift Eirini V Theodoraki Barbara Thorand David-Alexandre Tregouet Elena Tremoli Melanie M Van der Klauw Joyce B J van Meurs Sita H Vermeulen Jorma Viikari Jarmo Virtamo Veronique Vitart Gérard Waeber Zhaoming Wang Elisabeth Widén Sarah H Wild Gonneke Willemsen Bernhard R Winkelmann Jacqueline C M Witteman Bruce H R Wolffenbuttel Andrew Wong Alan F Wright M Carola Zillikens Philippe Amouyel Bernhard O Boehm Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock L Adrienne Cupples Daniele Cusi George V Dedoussis Jeanette Erdmann Johan G Eriksson Paul W Franks Philippe Froguel Christian Gieger Ulf Gyllensten Anders Hamsten Tamara B Harris Christian Hengstenberg Andrew A Hicks Aroon Hingorani Anke Hinney Albert Hofman Kees G Hovingh Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Karl-Heinz Jöckel Sirkka M Keinanen-Kiukaanniemi Lambertus A Kiemeney Diana Kuh Markku Laakso Terho Lehtimäki Douglas F Levinson Nicholas G Martin Andres Metspalu Andrew D Morris Markku S Nieminen Inger Njølstad Claes Ohlsson Albertine J Oldehinkel Willem H Ouwehand Lyle J Palmer Brenda Penninx Chris Power Michael A Province Bruce M Psaty Lu Qi Rainer Rauramaa Paul M Ridker Samuli Ripatti Veikko Salomaa Nilesh J Samani Harold Snieder Thorkild I A Sørensen Timothy D Spector Kari Stefansson Anke Tönjes Jaakko Tuomilehto André G Uitterlinden Matti Uusitupa Pim van der Harst Peter Vollenweider Henri Wallaschofski Nicholas J Wareham Hugh Watkins H-Erich Wichmann James F Wilson Goncalo R Abecasis Themistocles L Assimes Inês Barroso Michael Boehnke Ingrid B Borecki Panos Deloukas Caroline S Fox Timothy Frayling Leif C Groop Talin Haritunian Iris M Heid David Hunter Robert C Kaplan Fredrik Karpe Miriam F Moffatt Karen L Mohlke Jeffrey R O'Connell Yudi Pawitan Eric E Schadt David Schlessinger Valgerdur Steinthorsdottir David P Strachan Unnur Thorsteinsdottir Cornelia M van Duijn Peter M Visscher Anna Maria Di Blasio Joel N Hirschhorn Cecilia M Lindgren Andrew P Morris David Meyre André Scherag Mark I McCarthy Elizabeth K Speliotes Kari E North Ruth J F Loos Erik Ingelsson

Nat Genet 2013 May 7;45(5):501-12. Epub 2013 Apr 7.

US Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/ng.2606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973018PMC
May 2013

Loss-of-function mutations in MC4R are very rare in the Greek severely obese adult population.

Obesity (Silver Spring) 2012 Nov 26;20(11):2278-82. Epub 2012 Mar 26.

Department of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece.

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http://dx.doi.org/10.1038/oby.2012.77DOI Listing
November 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R König Kay-Tee Khaw Lee M Kaplan Åsa Johansson A Cecile J W Janssens Wilmar Igl G Kees Hovingh Christian Hengstenberg Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Leif C Groop Elena Gonzalez Nelson B Freimer Jeanette Erdmann Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Ulf de Faire Gabriel Crawford Yii-der I Chen Mark J Caulfield S Matthijs Boekholdt Themistocles L Assimes Thomas Quertermous Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Herman A Taylor Stacey B Gabriel Hilma Holm Vilmundur Gudnason Ronald M Krauss Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt David P Strachan Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Sekar Kathiresan

PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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September 2012

A genome-wide association search for type 2 diabetes genes in African Americans.

Authors:
Nicholette D Palmer Caitrin W McDonough Pamela J Hicks Bong H Roh Maria R Wing S Sandy An Jessica M Hester Jessica N Cooke Meredith A Bostrom Megan E Rudock Matthew E Talbert Joshua P Lewis Assiamira Ferrara Lingyi Lu Julie T Ziegler Michele M Sale Jasmin Divers Daniel Shriner Adebowale Adeyemo Charles N Rotimi Maggie C Y Ng Carl D Langefeld Barry I Freedman Donald W Bowden Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Andrew P Morris Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Claudia Langenberg Oliver M Hofmann Josée Dupuis Lu Qi Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis David J Couper Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Norman Klopp Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne John R B Perry Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Karen L Mohlke Andrew D Morris Colin N A Palmer Peter P Pramstaller Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Nicholas J Wareham Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Frank B Hu James B Meigs James S Pankow Oluf Pedersen H-Erich Wichmann Inês Barroso Jose C Florez Timothy M Frayling Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Toby Johnson Paul Elliott Denis Rybin Peter Henneman Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Josephine M Egan Taina Lajunen Alex Doney Stavroula Kanoni Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Rune Frants Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg Andrew A Hicks David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Antti Jula Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino Alisa K Manning María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Ben A Oostra Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Markus Perola Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Bruce M Psaty Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Toshiko Tanaka Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Ruth J F Loos Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Veikko Salomaa George Davey Smith Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper George V Dedoussis Manuel Serrano-Ríos Lars Lind Lyle J Palmer Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter David S Siscovick Brenda W J H Penninx Dorret I Boomsma Panos Deloukas Timothy D Spector Luigi Ferrucci Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Dawn M Waterworth Peter Vollenweider Leena Peltonen Vincent Mooser Robert Sladek

PLoS One 2012 4;7(1):e29202. Epub 2012 Jan 4.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251563PMC
May 2012

A genome-wide association meta-analysis identifies new childhood obesity loci.

Nat Genet 2012 May;44(5):526-31

Center for Applied Genomics, Abramson Research Center, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370100PMC
May 2012

Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population.

Obesity (Silver Spring) 2012 Feb 30;20(2):389-95. Epub 2011 Jun 30.

Department of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece.

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February 2012

Childhood obesity is associated with shorter leukocyte telomere length.

J Clin Endocrinol Metab 2011 May 24;96(5):1500-5. Epub 2011 Feb 24.

Department of Genomics of Common Disease, School of Public Health, Imperial College London, Burlington-Danes Building, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1210/jc.2010-2924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137462PMC
May 2011

Molecular basis of obesity: current status and future prospects.

Curr Genomics 2011 May;12(3):154-68

Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, CA 94608, USA.

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May 2011

Genetics of Obesity: What have we Learned?

Curr Genomics 2011 May;12(3):169-79

Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, Emeryville, California 94608, USA.

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May 2011

Evaluation of A2BP1 as an obesity gene.

Diabetes 2010 Nov 19;59(11):2837-45. Epub 2010 Aug 19.

Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Phoenix, Arizona, USA.

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November 2010

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Authors:
Elizabeth K Speliotes Cristen J Willer Sonja I Berndt Keri L Monda Gudmar Thorleifsson Anne U Jackson Hana Lango Allen Cecilia M Lindgren Jian'an Luan Reedik Mägi Joshua C Randall Sailaja Vedantam Thomas W Winkler Lu Qi Tsegaselassie Workalemahu Iris M Heid Valgerdur Steinthorsdottir Heather M Stringham Michael N Weedon Eleanor Wheeler Andrew R Wood Teresa Ferreira Robert J Weyant Ayellet V Segrè Karol Estrada Liming Liang James Nemesh Ju-Hyun Park Stefan Gustafsson Tuomas O Kilpeläinen Jian Yang Nabila Bouatia-Naji Tõnu Esko Mary F Feitosa Zoltán Kutalik Massimo Mangino Soumya Raychaudhuri Andre Scherag Albert Vernon Smith Ryan Welch Jing Hua Zhao Katja K Aben Devin M Absher Najaf Amin Anna L Dixon Eva Fisher Nicole L Glazer Michael E Goddard Nancy L Heard-Costa Volker Hoesel Jouke-Jan Hottenga Asa Johansson Toby Johnson Shamika Ketkar Claudia Lamina Shengxu Li Miriam F Moffatt Richard H Myers Narisu Narisu John R B Perry Marjolein J Peters Michael Preuss Samuli Ripatti Fernando Rivadeneira Camilla Sandholt Laura J Scott Nicholas J Timpson Jonathan P Tyrer Sophie van Wingerden Richard M Watanabe Charles C White Fredrik Wiklund Christina Barlassina Daniel I Chasman Matthew N Cooper John-Olov Jansson Robert W Lawrence Niina Pellikka Inga Prokopenko Jianxin Shi Elisabeth Thiering Helene Alavere Maria T S Alibrandi Peter Almgren Alice M Arnold Thor Aspelund Larry D Atwood Beverley Balkau Anthony J Balmforth Amanda J Bennett Yoav Ben-Shlomo Richard N Bergman Sven Bergmann Heike Biebermann Alexandra I F Blakemore Tanja Boes Lori L Bonnycastle Stefan R Bornstein Morris J Brown Thomas A Buchanan Fabio Busonero Harry Campbell Francesco P Cappuccio Christine Cavalcanti-Proença Yii-Der Ida Chen Chih-Mei Chen Peter S Chines Robert Clarke Lachlan Coin John Connell Ian N M Day Martin den Heijer Jubao Duan Shah Ebrahim Paul Elliott Roberto Elosua Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Maurizio F Facheris Stephan B Felix Pamela Fischer-Posovszky Aaron R Folsom Nele Friedrich Nelson B Freimer Mao Fu Stefan Gaget Pablo V Gejman Eco J C Geus Christian Gieger Anette P Gjesing Anuj Goel Philippe Goyette Harald Grallert Jürgen Grässler Danielle M Greenawalt Christopher J Groves Vilmundur Gudnason Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Alistair S Hall Aki S Havulinna Caroline Hayward Andrew C Heath Christian Hengstenberg Andrew A Hicks Anke Hinney Albert Hofman Georg Homuth Jennie Hui Wilmar Igl Carlos Iribarren Bo Isomaa Kevin B Jacobs Ivonne Jarick Elizabeth Jewell Ulrich John Torben Jørgensen Pekka Jousilahti Antti Jula Marika Kaakinen Eero Kajantie Lee M Kaplan Sekar Kathiresan Johannes Kettunen Leena Kinnunen Joshua W Knowles Ivana Kolcic Inke R König Seppo Koskinen Peter Kovacs Johanna Kuusisto Peter Kraft Kirsti Kvaløy Jaana Laitinen Olivier Lantieri Chiara Lanzani Lenore J Launer Cecile Lecoeur Terho Lehtimäki Guillaume Lettre Jianjun Liu Marja-Liisa Lokki Mattias Lorentzon Robert N Luben Barbara Ludwig Paolo Manunta Diana Marek Michel Marre Nicholas G Martin Wendy L McArdle Anne McCarthy Barbara McKnight Thomas Meitinger Olle Melander David Meyre Kristian Midthjell Grant W Montgomery Mario A Morken Andrew P Morris Rosanda Mulic Julius S Ngwa Mari Nelis Matt J Neville Dale R Nyholt Christopher J O'Donnell Stephen O'Rahilly Ken K Ong Ben Oostra Guillaume Paré Alex N Parker Markus Perola Irene Pichler Kirsi H Pietiläinen Carl G P Platou Ozren Polasek Anneli Pouta Suzanne Rafelt Olli Raitakari Nigel W Rayner Martin Ridderstråle Winfried Rief Aimo Ruokonen Neil R Robertson Peter Rzehak Veikko Salomaa Alan R Sanders Manjinder S Sandhu Serena Sanna Jouko Saramies Markku J Savolainen Susann Scherag Sabine Schipf Stefan Schreiber Heribert Schunkert Kaisa Silander Juha Sinisalo David S Siscovick Jan H Smit Nicole Soranzo Ulla Sovio Jonathan Stephens Ida Surakka Amy J Swift Mari-Liis Tammesoo Jean-Claude Tardif Maris Teder-Laving Tanya M Teslovich John R Thompson Brian Thomson Anke Tönjes Tiinamaija Tuomi Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Jorma Viikari Sophie Visvikis-Siest Veronique Vitart Carla I G Vogel Benjamin F Voight Lindsay L Waite Henri Wallaschofski G Bragi Walters Elisabeth Widen Susanna Wiegand Sarah H Wild Gonneke Willemsen Daniel R Witte Jacqueline C Witteman Jianfeng Xu Qunyuan Zhang Lina Zgaga Andreas Ziegler Paavo Zitting John P Beilby I Sadaf Farooqi Johannes Hebebrand Heikki V Huikuri Alan L James Mika Kähönen Douglas F Levinson Fabio Macciardi Markku S Nieminen Claes Ohlsson Lyle J Palmer Paul M Ridker Michael Stumvoll Jacques S Beckmann Heiner Boeing Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock Francis S Collins L Adrienne Cupples George Davey Smith Jeanette Erdmann Philippe Froguel Henrik Grönberg Ulf Gyllensten Per Hall Torben Hansen Tamara B Harris Andrew T Hattersley Richard B Hayes Joachim Heinrich Frank B Hu Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Jaakko Kaprio Fredrik Karpe Kay-Tee Khaw Lambertus A Kiemeney Heiko Krude Markku Laakso Debbie A Lawlor Andres Metspalu Patricia B Munroe Willem H Ouwehand Oluf Pedersen Brenda W Penninx Annette Peters Peter P Pramstaller Thomas Quertermous Thomas Reinehr Aila Rissanen Igor Rudan Nilesh J Samani Peter E H Schwarz Alan R Shuldiner Timothy D Spector Jaakko Tuomilehto Manuela Uda André Uitterlinden Timo T Valle Martin Wabitsch Gérard Waeber Nicholas J Wareham Hugh Watkins James F Wilson Alan F Wright M Carola Zillikens Nilanjan Chatterjee Steven A McCarroll Shaun Purcell Eric E Schadt Peter M Visscher Themistocles L Assimes Ingrid B Borecki Panos Deloukas Caroline S Fox Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Karen L Mohlke Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Cornelia M van Duijn H-Erich Wichmann Timothy M Frayling Unnur Thorsteinsdottir Gonçalo R Abecasis Inês Barroso Michael Boehnke Kari Stefansson Kari E North Mark I McCarthy Joel N Hirschhorn Erik Ingelsson Ruth J F Loos

Nat Genet 2010 Nov 10;42(11):937-48. Epub 2010 Oct 10.

Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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November 2010

Early detrimental metabolic outcomes of rs17300539-A allele of ADIPOQ gene despite higher adiponectinemia.

Obesity (Silver Spring) 2010 Jul 5;18(7):1469-73. Epub 2009 Nov 5.

Centre National de la Recherche Scientifique UMR8090, Pasteur Institute of Lille, Lille, France.

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July 2010

Genomic insights into early-onset obesity.

Genome Med 2010 Jun 23;2(6):36. Epub 2010 Jun 23.

CNRS UMR8199, Institute of Biology, Pasteur Institute, 1 Pr Calmette Street, 59000 Lille, France.

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June 2010

Study of TNFalpha -308G/A and IL6 -174G/C polymorphisms in type 2 diabetes and obesity risk in the Tunisian population.

Clin Biochem 2010 Apr 2;43(6):549-52. Epub 2010 Feb 2.

Laboratory of Genetics, Immunology and Human Pathologies, Faculty of Sciences of Tunis, 2092 Tunis, Tunisia.

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April 2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

Authors:
Richa Saxena Marie-France Hivert Claudia Langenberg Toshiko Tanaka James S Pankow Peter Vollenweider Valeriya Lyssenko Nabila Bouatia-Naji Josée Dupuis Anne U Jackson W H Linda Kao Man Li Nicole L Glazer Alisa K Manning Jian'an Luan Heather M Stringham Inga Prokopenko Toby Johnson Niels Grarup Trine W Boesgaard Cécile Lecoeur Peter Shrader Jeffrey O'Connell Erik Ingelsson David J Couper Kenneth Rice Kijoung Song Camilla H Andreasen Christian Dina Anna Köttgen Olivier Le Bacquer François Pattou Jalal Taneera Valgerdur Steinthorsdottir Denis Rybin Kristin Ardlie Michael Sampson Lu Qi Mandy van Hoek Michael N Weedon Yurii S Aulchenko Benjamin F Voight Harald Grallert Beverley Balkau Richard N Bergman Suzette J Bielinski Amelie Bonnefond Lori L Bonnycastle Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Thomas A Buchanan Suzannah J Bumpstead Christine Cavalcanti-Proença Guillaume Charpentier Yii-Der Ida Chen Peter S Chines Francis S Collins Marilyn Cornelis Gabriel J Crawford Jerome Delplanque Alex Doney Josephine M Egan Michael R Erdos Mathieu Firmann Nita G Forouhi Caroline S Fox Mark O Goodarzi Jürgen Graessler Aroon Hingorani Bo Isomaa Torben Jørgensen Mika Kivimaki Peter Kovacs Knut Krohn Meena Kumari Torsten Lauritzen Claire Lévy-Marchal Vladimir Mayor Jarred B McAteer David Meyre Braxton D Mitchell Karen L Mohlke Mario A Morken Narisu Narisu Colin N A Palmer Ruth Pakyz Laura Pascoe Felicity Payne Daniel Pearson Wolfgang Rathmann Annelli Sandbaek Avan Aihie Sayer Laura J Scott Stephen J Sharp Eric Sijbrands Andrew Singleton David S Siscovick Nicholas L Smith Thomas Sparsø Amy J Swift Holly Syddall Gudmar Thorleifsson Anke Tönjes Tiinamaija Tuomi Jaakko Tuomilehto Timo T Valle Gérard Waeber Andrew Walley Dawn M Waterworth Eleftheria Zeggini Jing Hua Zhao Thomas Illig H Erich Wichmann James F Wilson Cornelia van Duijn Frank B Hu Andrew D Morris Timothy M Frayling Andrew T Hattersley Unnur Thorsteinsdottir Kari Stefansson Peter Nilsson Ann-Christine Syvänen Alan R Shuldiner Mark Walker Stefan R Bornstein Peter Schwarz Gordon H Williams David M Nathan Johanna Kuusisto Markku Laakso Cyrus Cooper Michael Marmot Luigi Ferrucci Vincent Mooser Michael Stumvoll Ruth J F Loos David Altshuler Bruce M Psaty Jerome I Rotter Eric Boerwinkle Torben Hansen Oluf Pedersen Jose C Florez Mark I McCarthy Michael Boehnke Inês Barroso Robert Sladek Philippe Froguel James B Meigs Leif Groop Nicholas J Wareham Richard M Watanabe

Nat Genet 2010 Feb 17;42(2):142-8. Epub 2010 Jan 17.

Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922003PMC
February 2010

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

Authors:
Josée Dupuis Claudia Langenberg Inga Prokopenko Richa Saxena Nicole Soranzo Anne U Jackson Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Anna L Gloyn Cecilia M Lindgren Reedik Mägi Andrew P Morris Joshua Randall Toby Johnson Paul Elliott Denis Rybin Gudmar Thorleifsson Valgerdur Steinthorsdottir Peter Henneman Harald Grallert Abbas Dehghan Jouke Jan Hottenga Christopher S Franklin Pau Navarro Kijoung Song Anuj Goel John R B Perry Josephine M Egan Taina Lajunen Niels Grarup Thomas Sparsø Alex Doney Benjamin F Voight Heather M Stringham Man Li Stavroula Kanoni Peter Shrader Christine Cavalcanti-Proença Meena Kumari Lu Qi Nicholas J Timpson Christian Gieger Carina Zabena Ghislain Rocheleau Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Felicity Payne Rosa Maria Roccasecca François Pattou Praveen Sethupathy Kristin Ardlie Yavuz Ariyurek Beverley Balkau Philip Barter John P Beilby Yoav Ben-Shlomo Rafn Benediktsson Amanda J Bennett Sven Bergmann Murielle Bochud Eric Boerwinkle Amélie Bonnefond Lori L Bonnycastle Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Guillaume Charpentier Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Marilyn Cornelis Gabe Crawford Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Christian Dina Michael R Erdos Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Caroline S Fox Rune Frants Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Christopher J Groves Scott Grundy Rhian Gwilliam Ulf Gyllensten Samy Hadjadj Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Neelam Hassanali Caroline Hayward Simon C Heath Serge Hercberg Christian Herder Andrew A Hicks David R Hillman Aroon D Hingorani Albert Hofman Jennie Hui Joe Hung Bo Isomaa Paul R V Johnson Torben Jørgensen Antti Jula Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Valeriya Lyssenko Robert Mahley Massimo Mangino Alisa K Manning María Teresa Martínez-Larrad Jarred B McAteer Laura J McCulloch Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Mario A Morken Sutapa Mukherjee Silvia Naitza Narisu Narisu Matthew J Neville Ben A Oostra Marco Orrù Ruth Pakyz Colin N A Palmer Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Markus Perola Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Bruce M Psaty Wolfgang Rathmann Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Michael Roden Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Laura J Scott Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurethsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Toshiko Tanaka Barbara Thorand Jean Tichet Anke Tönjes Tiinamaija Tuomi André G Uitterlinden Ko Willems van Dijk Mandy van Hoek Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley G Bragi Walters Kim L Ward Hugh Watkins Michael N Weedon Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Eleftheria Zeggini Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Ruth J F Loos Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Andrew T Hattersley Kaisa Silander Veikko Salomaa George Davey Smith Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper George V Dedoussis Manuel Serrano-Ríos Andrew D Morris Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao James S Pankow Michael J Sampson Johanna Kuusisto Markku Laakso Torben Hansen Oluf Pedersen Peter Paul Pramstaller H Erich Wichmann Thomas Illig Igor Rudan Alan F Wright Michael Stumvoll Harry Campbell James F Wilson Richard N Bergman Thomas A Buchanan Francis S Collins Karen L Mohlke Jaakko Tuomilehto Timo T Valle David Altshuler Jerome I Rotter David S Siscovick Brenda W J H Penninx Dorret I Boomsma Panos Deloukas Timothy D Spector Timothy M Frayling Luigi Ferrucci Augustine Kong Unnur Thorsteinsdottir Kari Stefansson Cornelia M van Duijn Yurii S Aulchenko Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Dawn M Waterworth Peter Vollenweider Leena Peltonen Vincent Mooser Goncalo R Abecasis Nicholas J Wareham Robert Sladek Philippe Froguel Richard M Watanabe James B Meigs Leif Groop Michael Boehnke Mark I McCarthy Jose C Florez Inês Barroso

Nat Genet 2010 Feb 17;42(2):105-16. Epub 2010 Jan 17.

Department of Biostatistics, Boston University School of Public Health, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018764PMC
February 2010

A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity.

Obesity (Silver Spring) 2009 Aug 19;17(8):1549-53. Epub 2009 Mar 19.

Section of Genomic Medicine, Imperial College London, Hammersmith Hospital, London, UK.

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http://dx.doi.org/10.1038/oby.2009.75DOI Listing
August 2009

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians.

Diabetes 2009 Jul 28;58(7):1682-9. Epub 2009 Apr 28.

Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, NIH, Phoenix, AZ, USA.

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http://dx.doi.org/10.2337/db09-0028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699863PMC
July 2009

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.

Obesity (Silver Spring) 2009 Apr 22;17(4):745-54. Epub 2009 Jan 22.

Department of Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1038/oby.2008.589DOI Listing
April 2009