Publications by authors named "David M Wilson"

100Publications

Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.

Prog Biophys Mol Biol 2020 Oct 25. Epub 2020 Oct 25.

Accelero Biostructures Inc., San Francisco, CA, USA; XPose Therapeutics Inc., San Carlos, CA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pbiomolbio.2020.10.005DOI Listing
October 2020

Nuclear imaging of bacterial infection- state of the art and future directions.

J Nucl Med 2020 Aug 6. Epub 2020 Aug 6.

University of California, San Francisco, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.120.244939DOI Listing
August 2020

Small Molecule Sensors Targeting the Bacterial Cell Wall.

ACS Infect Dis 2020 07 9;6(7):1587-1598. Epub 2020 Jun 9.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsinfecdis.9b00515DOI Listing
July 2020

Simultaneous Metabolic and Perfusion Imaging Using Hyperpolarized C MRI Can Evaluate Early and Dose-Dependent Response to Radiation Therapy in a Prostate Cancer Mouse Model.

Int J Radiat Oncol Biol Phys 2020 Aug 25;107(5):887-896. Epub 2020 Apr 25.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, California; Graduate Program in Bioengineering, University of California, Berkeley and University of California, San Francisco, California. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2020.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381368PMC
August 2020

Arabinofuranose-derived positron-emission tomography radiotracers for detection of pathogenic microorganisms.

J Labelled Comp Radiopharm 2020 May 28;63(5):231-239. Epub 2020 Mar 28.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jlcr.3835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364301PMC
May 2020

Sensing Living Bacteria Using d-Alanine-Derived C Radiotracers.

ACS Cent Sci 2020 Feb 4;6(2):155-165. Epub 2020 Feb 4.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acscentsci.9b00743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047270PMC
February 2020

Hyperpolarized pH imaging reveals grade-dependent acidification in prostate cancer.

Oncotarget 2019 Oct 22;10(58):6096-6110. Epub 2019 Oct 22.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.27225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817439PMC
October 2019

The Effects of Special Patient Population Plasma on Pharmacokinetic Quantifications Using LC-MS/MS.

Drug Metab Lett 2019 ;13(2):111-122

Bioanalytical Department, Ardea Biosciences / AstraZeneca, San Diego, CA, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1872312813666191015162634DOI Listing
May 2020

DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging.

Am J Hum Genet 2019 08;105(2):237-257

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2019.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693886PMC
August 2019

Amino Acid-Derived Sensors for Specific Zn Detection Using Hyperpolarized C Magnetic Resonance Spectroscopy.

Chemistry 2019 Sep 20;25(51):11842-11846. Epub 2019 Aug 20.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA (USA, 94107, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/chem.201902771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742520PMC
September 2019

Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers.

Clin Pharmacol Drug Dev 2019 07 13;8(5):657-663. Epub 2019 Feb 13.

AstraZeneca, Gaithersburg, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpdd.662DOI Listing
July 2019

Experimental free ligand conformations: a missing link in structure-based drug discovery.

Future Med Chem 2019 01 16;11(2):79-82. Epub 2019 Jan 16.

Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/fmc-2018-0339DOI Listing
January 2019

Imaging-Based Approach to Extradural Infections of the Spine.

Semin Ultrasound CT MR 2018 12 26;39(6):570-586. Epub 2018 Sep 26.

Department of Radiology and Biomedical Imaging, University of California, San Francisco.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.sult.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291848PMC
December 2018

Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins.

Sci Rep 2018 11 30;8(1):17490. Epub 2018 Nov 30.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd., Ste. 100, Baltimore, MD, 21224, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-36027-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269539PMC
November 2018

Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad Atropisomers.

Drug Metab Dispos 2019 02 15;47(2):104-113. Epub 2018 Nov 15.

Preclinical and Clinical DMPK (C.Y., Z.S., C.A.L.), Bioanalytical (D.Z., D.M.W.), Biology (J.N.M.), and Chemistry (M.R., J.-L.G.) Departments, Ardea Biosciences, Inc., San Diego, California

View Article

Download full-text PDF

Source
http://dmd.aspetjournals.org/lookup/doi/10.1124/dmd.118.0805
Publisher Site
http://dx.doi.org/10.1124/dmd.118.080549DOI Listing
February 2019

Metabolism and disposition of lesinurad, a uric acid reabsorption inhibitor, in humans.

Xenobiotica 2019 Jul 12;49(7):811-822. Epub 2018 Sep 12.

a Preclinical and Clinical DMPK , San Diego , CA , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00498254.2018.1504257DOI Listing
July 2019

Measuring glucocorticoid receptor expression with PET.

Oncotarget 2018 Apr 17;9(29):20399-20408. Epub 2018 Apr 17.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.24911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945515PMC
April 2018

APE1 deficiency promotes cellular senescence and premature aging features.

Nucleic Acids Res 2018 06;46(11):5664-5677

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd., Ste. 100, Baltimore, MD 21224, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gky326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009672PMC
June 2018

Clinical Utility of Diffusion-Weighted Imaging in Spinal Infections.

Clin Neuroradiol 2019 Sep 26;29(3):515-522. Epub 2018 Mar 26.

Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, Rm. L-358, 94143-0628, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00062-018-0681-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158113PMC
September 2019

Organic synthesis provides opportunities to transform drug discovery.

Nat Chem 2018 04 22;10(4):383-394. Epub 2018 Mar 22.

Medicinal Sciences, Pfizer, Inc., Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41557-018-0021-zDOI Listing
April 2018

Metabolism and Disposition of Verinurad, a Uric Acid Reabsorption Inhibitor, in Humans.

Drug Metab Dispos 2018 05 28;46(5):532-541. Epub 2018 Feb 28.

Preclinical and Clinical DMPK (C.A.L., C.Y.,V.S., Z.S.), Bioanalytical (D.M.W.), Biology (T.M.O.), Chemistry (J.-L.G.), and Clinical Development (J.H.) Ardea Biosciences, Inc., San Diego, California; and Early Clinical Development, IMED Biotech Unit, Quantitative Clinical Pharmacology (M.G.) AstraZeneca LP, Gaithersburg, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/dmd.117.078220DOI Listing
May 2018

Pharmacokinetics, safety, and patient acceptability of subcutaneous versus intramuscular testosterone injection for gender-affirming therapy: A pilot study.

Am J Health Syst Pharm 2018 03 24;75(6):351-358. Epub 2018 Jan 24.

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2146/ajhp170160DOI Listing
March 2018

Direct assessment of renal mitochondrial redox state using hyperpolarized C-acetoacetate.

Magn Reson Med 2018 04 3;79(4):1862-1869. Epub 2018 Jan 3.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrm.27054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815327PMC
April 2018

Development of a Cell-Based Assay for Measuring Base Excision Repair Responses.

Sci Rep 2017 10 11;7(1):13007. Epub 2017 Oct 11.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Blvd., Ste. 100, Baltimore, MD, 21224, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-017-12963-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636817PMC
October 2017

Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans.

Nucleic Acids Res 2017 Sep;45(16):9467-9480

Institute for Genome Stability in Aging and Disease, Medical Faculty, Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne (CMMC) and Systems Biology of Ageing Cologne (Sybacol), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkx660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164PMC
September 2017

The Role of PET/MR Imaging in Precision Medicine.

PET Clin 2017 Oct 28;12(4):489-501. Epub 2017 Jul 28.

Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA; Department of Radiology, San Francisco VA Health Care System, 4150 Clement Street, San Francisco, CA 94121, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cpet.2017.05.006DOI Listing
October 2017

Exploring Metabolism In Vivo Using Endogenous C Metabolic Tracers.

Semin Nucl Med 2017 09 11;47(5):461-473. Epub 2017 Jul 11.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.semnuclmed.2017.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037183PMC
September 2017

A novel quantitative method for recovering precipitated uric acid in urine and analysis by LC-MS/MS.

Bioanalysis 2017 Mar 13;9(5):447-457. Epub 2017 Feb 13.

Ardea Biosciences, 9390 Towne Centre Drive, San Diego, CA 92121, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/bio-2016-0238DOI Listing
March 2017

Tumor-associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes.

Environ Mol Mutagen 2017 03 9;58(2):84-98. Epub 2017 Feb 9.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/em.22074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321783PMC
March 2017

A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.

Nucleic Acids Res 2017 04;45(6):3242-3252

Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
Publisher Site
http://dx.doi.org/10.1093/nar/gkx015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389632PMC
April 2017

Coordination of DNA single strand break repair.

Free Radic Biol Med 2017 06 24;107:228-244. Epub 2016 Nov 24.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2016.11.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443707PMC
June 2017

In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapy.

Biomed Microdevices 2016 12;18(6):98

Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry St, Suite 350, Room 320, San Francisco, CA, 94107-5705, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10544-016-0124-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441460PMC
December 2016

Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.

Bioorg Med Chem Lett 2016 10 23;26(19):4606-4612. Epub 2016 Aug 23.

AstraZeneca, Hodgkin Building, Chesterford Research Campus, Little Chesterford, Saffron Walden, Cambs. CB10 1XL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2016.08.070DOI Listing
October 2016

A reactivity-based [F]FDG probe for formaldehyde imaging using positron emission tomography.

Chem Sci 2016 Aug 25;7(8):5503-5507. Epub 2016 May 25.

Department of Chemistry , University of Berkeley , Berkeley , CA 94720 , USA . Email:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c6sc01503dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021783PMC
August 2016

Standing on the shoulders of giants: a retrospective analysis of kinase drug discovery at AstraZeneca.

Drug Discov Today 2016 10 15;21(10):1596-1608. Epub 2016 Jun 15.

AstraZeneca, Oncology iMED, Hodgkin Building, Chesterford Research Campus, Little Chesterford, Saffron Walden, Cambridgeshire CB10 1XL, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2016.06.007DOI Listing
October 2016

Performance of magnetic resonance imaging in the evaluation of first-time and reoperative primary hyperparathyroidism.

Surgery 2016 09 16;160(3):747-54. Epub 2016 Jun 16.

Department of Surgery, University of California, San Francisco, CA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.surg.2016.05.003DOI Listing
September 2016

The Potential of Metabolic Imaging.

Semin Nucl Med 2016 Jan;46(1):28-39

Department of Radiology and Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.semnuclmed.2015.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686865PMC
January 2016

Elements That Regulate the DNA Damage Response of Proteins Defective in Cockayne Syndrome.

J Mol Biol 2016 Jan 23;428(1):62-78. Epub 2015 Nov 23.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2015.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738086PMC
January 2016

CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine.

Sci Transl Med 2015 Sep;7(305):305ra145

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94117, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.aac6589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854290PMC
September 2015

Reduced Nuclease Activity of Apurinic/Apyrimidinic Endonuclease (APE1) Variants on Nucleosomes: IDENTIFICATION OF ACCESS RESIDUES.

J Biol Chem 2015 Aug 1;290(34):21067-75. Epub 2015 Jul 1.

the Laboratory of Molecular Gerontology, National Institute on Aging, IRP, National Institutes of Health, Baltimore, Maryland 21224.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M115.665547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543664PMC
August 2015

Partial loss of the DNA repair scaffolding protein, Xrcc1, results in increased brain damage and reduced recovery from ischemic stroke in mice.

Neurobiol Aging 2015 Jul 17;36(7):2319-2330. Epub 2015 Apr 17.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program (NIA IRP), Biomedical Research Center, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2015.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576895PMC
July 2015

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.

Nat Chem Biol 2015 Mar 26;11(3):189-91. Epub 2015 Jan 26.

1] EpiNova DPU, Immuno-Inflammation Therapy Area, GlaxoSmithKline,Medicines Research Centre, Stevenage, Hertfordshire, UK. [2] AstraZeneca, Oncology iMed, Cambridge Science Park, Cambridge, UK (R.J.S. and D.M.W.); Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA (D.J.S.); University of Massachussetts Medical School, Worcester, Massachusetts, USA (P.R.T.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nchembio.1735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397581PMC
March 2015

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.

Nucleic Acids Res 2015 Jan 10;43(1):247-58. Epub 2014 Dec 10.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku1279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288174PMC
January 2015

Protecting the mitochondrial powerhouse.

Trends Cell Biol 2015 Mar 11;25(3):158-70. Epub 2014 Dec 11.

Laboratory of Molecular Gerontology, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, MD 21224, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcb.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576887PMC
March 2015

Base excision repair capacity in informing healthspan.

Carcinogenesis 2014 Dec 29;35(12):2643-52. Epub 2014 Oct 29.

Laboratory of Molecular Gerontology, National Institute on Aging, Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgu225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247524PMC
December 2014

Hyperpolarized 13C MR for molecular imaging of prostate cancer.

J Nucl Med 2014 Oct 28;55(10):1567-72. Epub 2014 Aug 28.

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.114.141705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349324PMC
October 2014

Isolated intracerebral light chain deposition disease: novel imaging and pathologic findings.

Clin Imaging 2014 Nov-Dec;38(6):868-71. Epub 2014 Jul 2.

University of California, San Francisco, Department of Radiology and Biomedical Imaging, 505 Parnassus Ave., M-391, San Francisco, CA 94143-0628.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clinimag.2014.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854295PMC
June 2015

Temperature systematically modifies neural activity for sweet taste.

J Neurophysiol 2014 Oct 25;112(7):1667-77. Epub 2014 Jun 25.

Department of Biology, The University of Oklahoma, Norman, Oklahoma

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/jn.00368.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157175PMC
October 2014

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.

Mol Oncol 2014 Oct 13;8(7):1326-38. Epub 2014 May 13.

Department of Oncology, Nottingham University Hospitals, Nottingham NG51PB, UK; Academic Unit of Oncology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molonc.2014.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690463PMC
October 2014