Publications by authors named "David M Kent"

99Publications

Predictive approaches to heterogeneous treatment effects: a scoping review.

BMC Med Res Methodol 2020 Oct 23;20(1):264. Epub 2020 Oct 23.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center, 800 Washington St, Box 63, Boston, MA, 02111, USA.

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http://dx.doi.org/10.1186/s12874-020-01145-1DOI Listing
October 2020

Prehospital Triage Strategies for the Transportation of Suspected Stroke Patients in the United States.

Stroke 2020 Oct 7:STROKEAHA120031144. Epub 2020 Oct 7.

Predictive Analytics and Comparative Effectiveness Center, Tufts Medical Center, Boston, MA (J.N., D.M.K.).

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http://dx.doi.org/10.1161/STROKEAHA.120.031144DOI Listing
October 2020

Fear of Coronavirus Disease 2019-An Emerging Cardiac Risk.

JAMA Cardiol 2020 09;5(9):981-982

Cardiovascular Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamacardio.2020.2890DOI Listing
September 2020

Can Clinical Predictive Models Identify Patients Who Should Not Receive TAVR? A Systematic Review.

Struct Heart 2020 9;4(4):295-299. Epub 2020 Jul 9.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Tufts Medical Center.

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http://dx.doi.org/10.1080/24748706.2020.1782549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7469888PMC
July 2020

Predictably unequal: understanding and addressing concerns that algorithmic clinical prediction may increase health disparities.

NPJ Digit Med 2020 30;3:99. Epub 2020 Jul 30.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, Boston, MA USA.

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http://dx.doi.org/10.1038/s41746-020-0304-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393367PMC
July 2020

Clinical Predictive Models of Sudden Cardiac Arrest: A Survey of the Current Science and Analysis of Model Performances.

J Am Heart Assoc 2020 Aug 13;9(16):e017625. Epub 2020 Aug 13.

Predictive Analytics and Comparative Effectiveness Center Institute for Clinical Research and Health Policy Studies Tufts Medical Center Boston MA.

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http://dx.doi.org/10.1161/JAHA.119.017625DOI Listing
August 2020

Why clinical trials may not help patients make treatment decisions: results from focus group discussions with 22 patients.

J Comp Eff Res 2020 Jun 7;9(9):651-658. Epub 2020 Jul 7.

Tufts University School of Medicine, Boston, MA 02111, USA.

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http://dx.doi.org/10.2217/cer-2020-0033DOI Listing
June 2020

The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement.

Ann Intern Med 2020 Jun;172(11):776

Tufts Medical Center, Boston, MA (D.M.K.).

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http://dx.doi.org/10.7326/L20-0427DOI Listing
June 2020

When predictions are used to allocate scarce health care resources: three considerations for models in the era of Covid-19.

Diagn Progn Res 2020 20;4:11. Epub 2020 May 20.

3Feinstein Institutes for Medical Research, Northwell Health, New York City, NY USA.

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http://dx.doi.org/10.1186/s41512-020-00079-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238723PMC
May 2020

Practice advisory update summary: Patent foramen ovale and secondary stroke prevention: Report of the Guideline Subcommittee of the American Academy of Neurology.

Neurology 2020 05 29;94(20):876-885. Epub 2020 Apr 29.

From the Department of Neurology (S.R.M., S.E.K.), University of Pennsylvania School of Medicine, Philadelphia; Department of Neurology (G.S.G., L.R.), University of Kansas Medical Center, MO; Institute for Clinical Research and Health Policy Studies (D.M.K.), Tufts University School of Medicine, Boston, MA; Cardiology Section (J.R.K.), San Francisco Veterans Affairs Health Care System, and Departments of Medicine, and Epidemiology and Biostatistics (J.R.K.), University of California San Francisco; Division of Cardiology (S.H.), Columbia University Medical Center, New York; Department of Medicine (Cardiology) (J.D.C.), University of Colorado School of Medicine, Aurora; Department of Neurology (K.I.), New York University; and Department of Neurology (N.S.), Kaiser Permanente, Los Angeles, CA.

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http://dx.doi.org/10.1212/WNL.0000000000009443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526671PMC
May 2020

Chronic Conditions in Advanced Cardiac Disease: A Cluster Analysis of Transcatheter Aortic Valve Replacement (TAVR)-Treated Patients.

J Gen Intern Med 2020 Jul 9;35(7):2231-2233. Epub 2020 Jan 9.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Tufts Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1007/s11606-019-05625-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351902PMC
July 2020

Re: Selecting Optimal Subgroups for Treatment Using Many Covariates.

Epidemiology 2020 May;31(3):e30-e31

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center, Boston, MA Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center, Boston, MA Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1097/EDE.0000000000001156DOI Listing
May 2020

Clinical Prediction Models for Valvular Heart Disease.

J Am Heart Assoc 2019 10 4;8(20):e011972. Epub 2019 Oct 4.

Predictive Analytics and Comparative Effectiveness (PACE) Center Institute for Clinical Research and Health Policy Studies (ICRHPS) Tufts Medical Center Boston MA.

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http://dx.doi.org/10.1161/JAHA.119.011972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818049PMC
October 2019

Models with interactions overestimated heterogeneity of treatment effects and were prone to treatment mistargeting.

J Clin Epidemiol 2019 10 10;114:72-83. Epub 2019 Jun 10.

Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jclinepi.2019.05.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497896PMC
October 2019

Patients' responses to incidentally discovered silent brain infarcts - a qualitative study.

J Patient Rep Outcomes 2019 Apr 15;3(1):23. Epub 2019 Apr 15.

Predictive Analytics and Comparative Effectiveness Center, Tufts Medical Center, Boston, USA.

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http://dx.doi.org/10.1186/s41687-019-0112-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462438PMC
April 2019

Atrial fibrillation ablation in practice: assessing CABANA generalizability.

Eur Heart J 2019 04;40(16):1257-1264

Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, 200 1st St SW, Rochester, MN, USA.

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http://dx.doi.org/10.1093/eurheartj/ehz085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475520PMC
April 2019

Targeted Incentive Programs For Lung Cancer Screening Can Improve Population Health And Economic Efficiency.

Health Aff (Millwood) 2019 01;38(1):60-67

Peter J. Neumann is a professor of medicine in the School of Medicine, Tufts University, and director of the Center for the Evaluation of Value and Risk in Health, Tufts Medical Center.

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http://www.healthaffairs.org/doi/10.1377/hlthaff.2018.05148
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http://dx.doi.org/10.1377/hlthaff.2018.05148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409129PMC
January 2019

Scoring System to Optimize Pioglitazone Therapy After Stroke Based on Fracture Risk.

Stroke 2018 Dec 10:STROKEAHA118022745. Epub 2018 Dec 10.

From the Department of Internal Medicine, General Medicine, Yale University School of Medicine, New Haven, CT (C.M.V., W.N.K.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557695PMC
December 2018

Personalized evidence based medicine: predictive approaches to heterogeneous treatment effects.

BMJ 2018 12 10;363:k4245. Epub 2018 Dec 10.

Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA.

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http://dx.doi.org/10.1136/bmj.k4245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889830PMC
December 2018

Risk-Targeted Lung Cancer Screening.

Ann Intern Med 2018 08;169(3):200-201

Tufts Medical Center, Boston, Massachusetts (V.K., J.T.C., P.J.N., D.M.K.).

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http://dx.doi.org/10.7326/L18-0237DOI Listing
August 2018

Population-Based Validation of a Clinical Prediction Model for Congenital Diaphragmatic Hernias.

J Pediatr 2018 10 25;201:160-165.e1. Epub 2018 Jun 25.

Division of Pediatric Surgery, Mattel Children's Hospital at UCLA, Los Angeles, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2018.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153029PMC
October 2018

Big Data and Predictive Analytics: Recalibrating Expectations.

JAMA 2018 07;320(1):27-28

Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2018.5602DOI Listing
July 2018

Evaluation of person-level heterogeneity of treatment effects in published multiperson N-of-1 studies: systematic review and reanalysis.

BMJ Open 2018 05 26;8(5):e017641. Epub 2018 May 26.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/bmjopen-2017-017641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988083PMC
May 2018

Effects of Race Are Rarely Included in Clinical Prediction Models for Cardiovascular Disease.

J Gen Intern Med 2018 09;33(9):1429-1430

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, 800 Washington Street, Box #63, Boston, MA, 02111, USA.

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http://dx.doi.org/10.1007/s11606-018-4475-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109012PMC
September 2018

Absolute Lymphocyte Count: A Predictor of Recurrent Cytomegalovirus Disease in Solid Organ Transplant Recipients.

Clin Infect Dis 2018 10;67(9):1395-1402

Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1093/cid/ciy295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927884PMC
October 2018

Clinicians' perspectives on incidentally discovered silent brain infarcts - A qualitative study.

PLoS One 2018 29;13(3):e0194971. Epub 2018 Mar 29.

Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194971PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875806PMC
July 2018

Patient Variability Seldom Assessed in Cost-effectiveness Studies.

Med Decis Making 2018 05 19;38(4):487-494. Epub 2018 Jan 19.

Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1177/0272989X17746989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882686PMC
May 2018

Risk-Targeted Lung Cancer Screening: A Cost-Effectiveness Analysis.

Ann Intern Med 2018 02 2;168(3):161-169. Epub 2018 Jan 2.

Tufts Medical Center, Boston, Massachusetts (V.K., J.T.C., J.B.W., P.J.N., D.M.K.).

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http://dx.doi.org/10.7326/M17-1401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533918PMC
February 2018

Digoxin Benefit Varies by Risk of Heart Failure Hospitalization: Applying the Tufts MC HF Risk Model.

Am J Med 2018 06 25;131(6):676-683.e2. Epub 2017 Dec 25.

The Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Mass.

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http://dx.doi.org/10.1016/j.amjmed.2017.12.010DOI Listing
June 2018

Tufts PACE Clinical Predictive Model Registry: update 1990 through 2015.

Diagn Progn Res 2017 21;1:20. Epub 2017 Dec 21.

2Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, 800 Washington Street, Box 63, Boston, MA 02111 USA.

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http://dx.doi.org/10.1186/s41512-017-0021-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460840PMC
December 2017

Regional Validation and Recalibration of Clinical Predictive Models for Patients With Acute Heart Failure.

J Am Heart Assoc 2017 Nov 18;6(11). Epub 2017 Nov 18.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.117.006121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721739PMC
November 2017

The proposed 'concordance-statistic for benefit' provided a useful metric when modeling heterogeneous treatment effects.

J Clin Epidemiol 2018 02 11;94:59-68. Epub 2017 Nov 11.

Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, 800 Washington St, Boston, MA 02111, USA.

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http://dx.doi.org/10.1016/j.jclinepi.2017.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448760PMC
February 2018

Role of Secondary Prophylaxis With Valganciclovir in the Prevention of Recurrent Cytomegalovirus Disease in Solid Organ Transplant Recipients.

Clin Infect Dis 2017 Nov;65(12):2000-2007

Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center and Tufts University School of Medicine.

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http://dx.doi.org/10.1093/cid/cix696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850558PMC
November 2017

Biases in Individualized Cost-effectiveness Analysis: Influence of Choices in Modeling Short-Term, Trial-Based, Mortality Risk Reduction and Post-Trial Life Expectancy.

Med Decis Making 2017 10 20;37(7):770-778. Epub 2017 Mar 20.

Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands (DVK, EWS).

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http://dx.doi.org/10.1177/0272989X17696994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638644PMC
October 2017

Comparison of the CHADS-VASc, CHADS, HAS-BLED, ORBIT, and ATRIA Risk Scores in Predicting Non-Vitamin K Antagonist Oral Anticoagulants-Associated Bleeding in Patients With Atrial Fibrillation.

Am J Cardiol 2017 Nov 31;120(9):1549-1556. Epub 2017 Jul 31.

Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.07.051DOI Listing
November 2017

Race and Ethnicity: A Part of the Equation for Personalized Clinical Decision Making?

Circ Cardiovasc Qual Outcomes 2017 07;10(7)

From the Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1161/CIRCOUTCOMES.117.003823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558842PMC
July 2017

Understanding the Value of Individualized Information: The Impact of Poor Calibration or Discrimination in Outcome Prediction Models.

Med Decis Making 2017 10 11;37(7):790-801. Epub 2017 Apr 11.

Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA (NO, JTC, PJN, JBW, DMK).

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http://dx.doi.org/10.1177/0272989X17704855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577366PMC
October 2017

Response to Comment on Shahraz et al. Do Patient Characteristics Impact Decisions by Clinicians on Hemoglobin A1c Targets? Diabetes Care 2016;38: e145-e146.

Diabetes Care 2016 12;39(12):e228

Predictive Analytics and Comparative Effectiveness Center, Tufts Medical Center, Boston, MA.

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http://dx.doi.org/10.2337/dci16-0029DOI Listing
December 2016

Using group data to treat individuals: understanding heterogeneous treatment effects in the age of precision medicine and patient-centred evidence.

Int J Epidemiol 2016 12;45(6):2184-2193

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.

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http://dx.doi.org/10.1093/ije/dyw125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841616PMC
December 2016

Survival Analyses and Prognosis of Plasma-Cell Myeloma and Plasmacytoma-Like Posttransplantation Lymphoproliferative Disorders.

Clin Lymphoma Myeloma Leuk 2016 12 17;16(12):684-692.e3. Epub 2016 Sep 17.

Division of Hematology/Oncology, Department of Internal Medicine, Tufts University School of Medicine, Boston, MA; Division of Hematology/Oncology, Department of Internal Medicine, Tufts Cancer Center, Boston, MA; Department of Internal Medicine, Tufts Medical Center, Boston, MA.

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http://dx.doi.org/10.1016/j.clml.2016.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402751PMC
December 2016

Prediabetes Risk in Adult Americans According to a Risk Test.

JAMA Intern Med 2016 12;176(12):1861-1863

Predictive Analytics and Comparative Effectiveness Center, Tufts Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamainternmed.2016.5919DOI Listing
December 2016

Development and Validation of a Predictive Model for Short- and Medium-Term Hospital Readmission Following Heart Valve Surgery.

J Am Heart Assoc 2016 08 31;5(9). Epub 2016 Aug 31.

Department of Internal Medicine, Baystate Medical Center, Springfield, MA Center for Quality of Care Research, Baystate Medical Center, Springfield, MA Tufts University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.116.003544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079019PMC
August 2016

Multistate Model to Predict Heart Failure Hospitalizations and All-Cause Mortality in Outpatients With Heart Failure With Reduced Ejection Fraction: Model Derivation and External Validation.

Circ Heart Fail 2016 08;9(8)

From The CardioVascular Center (J.N.U., M.A.K., G.S.H.) and The Institute for Clinical Research and Health Policy Studies (D.v.K., F.N., D.M.K.), Tufts Medical Center, Boston, MA; and The Department of Public Health, Erasmus MC, University Medical Center Rotterdam, The Netherlands (D.v.K.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328587PMC
August 2016

Practice advisory: Recurrent stroke with patent foramen ovale (update of practice parameter): Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.

Neurology 2016 Aug 27;87(8):815-21. Epub 2016 Jul 27.

From the Department of Neurology (S.R.M., S.E.K.), University of Pennsylvania School of Medicine, Philadelphia; Department of Neurology (G.G., L.R.), University of Kansas Medical Center, Kansas City; Institute for Clinical Research and Health Policy Studies (D.M.K.), Tufts University School of Medicine, Boston, MA; Departments of Medicine (Cardiology) and Epidemiology and Population Health (J.R.K.), Albert Einstein College of Medicine, Bronx; and Division of Cardiology (S.H.), Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1212/WNL.0000000000002961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999319PMC
August 2016

Risk and treatment effect heterogeneity: re-analysis of individual participant data from 32 large clinical trials.

Int J Epidemiol 2016 12;45(6):2075-2088

Department of Internal Medicine and Department of Health Management and Policy, University of Michigan, Ann Arbor, MI, USA.

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http://ije.oxfordjournals.org/content/early/2016/07/02/ije.d
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http://dx.doi.org/10.1093/ije/dyw118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841614PMC
December 2016

Do Patient Characteristics Impact Decisions by Clinicians on Hemoglobin A1c Targets?

Diabetes Care 2016 09 22;39(9):e145-6. Epub 2016 Jun 22.

Predictive Analytics and Comparative Effectiveness Center, Tufts Medical Center, Boston, MA.

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http://dx.doi.org/10.2337/dc16-0532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314695PMC
September 2016

Field Synopsis of the Role of Sex in Stroke Prediction Models.

J Am Heart Assoc 2016 05 5;5(5). Epub 2016 May 5.

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.115.002809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889171PMC
May 2016

A predictive model to identify patients with suspected acute coronary syndromes at high risk of cardiac arrest or in-hospital mortality: An IMMEDIATE Trial sub-study

Int J Cardiol Heart Vasc 2015 12 27;9:37-42. Epub 2015 Aug 27.

Center for Cardiovascular Health Services Research, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, United States; Tufts Clinical and Translational Science Institute, Tufts University, Boston, MA, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762054PMC
http://dx.doi.org/10.1016/j.ijcha.2015.07.001DOI Listing
December 2015

Field Synopsis of Sex in Clinical Prediction Models for Cardiovascular Disease.

Circ Cardiovasc Qual Outcomes 2016 Feb;9(2 Suppl 1):S8-15

Predictive Analytics and Comparative Effectiveness (PACE) Center (J.K.P., B.S.W., C.L., L.L.Y.L., J.S.L., D.M.K.), Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine and Center for Clinical Evidence Synthesis (G.R.), Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, Boston, MA; and Division of Cardiology, Tufts Medical Center, Boston, MA (B.S.W.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.115.002473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573163PMC
February 2016

Hospitals' Patterns of Use of Noninvasive Ventilation in Patients With Asthma Exacerbation.

Chest 2016 Mar 28;149(3):729-36. Epub 2015 Dec 28.

Center for Quality of Care Research, Baystate Medical Center, Springfield, MA; Division of Hospital Medicine, Baystate Medical Center, Springfield, MA; Department of Medicine, Tufts University School of Medicine, Boston, MA.

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http://journal.publications.chestnet.org/data/Journals/CHEST
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http://linkinghub.elsevier.com/retrieve/pii/S001236921500342
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http://dx.doi.org/10.1016/j.chest.2015.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944771PMC
March 2016

Three simple rules to ensure reasonably credible subgroup analyses.

BMJ 2015 Nov 4;351:h5651. Epub 2015 Nov 4.

VA Center for Clinical Management and Research, Ann Arbor Department of Internal Medicine, University of Michigan School of Medicine.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632208PMC
http://dx.doi.org/10.1136/bmj.h5651DOI Listing
November 2015

Patient-Centered Decision Support in Acute Ischemic Stroke: Qualitative Study of Patients' and Providers' Perspectives.

Circ Cardiovasc Qual Outcomes 2015 Oct;8(6 Suppl 3):S109-16

From the School of Nursing (C.D.) and Department of Biomedical and Health Informatics, School of Medicine (J.A.S.), University of Missouri-Kansas City; Cardiovascular Outcomes Research, Saint Luke's Hospital of Kansas City (C.D., E.C., E.G., B.G., D.S., J.A.S.); Department of Neurology, Geffen School of Medicine at UCLA (M.E.Q., E.C.) and UCLA Comprehensive Stroke Center (J.L.S.); Center for Advanced Brain and Neurological Care, University of Kansas Hospital (M.R.); US Medical Affairs, Cardiometabolism/Neuroscience, Genentech (E.C.); and Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA (D.M.K.).

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October 2015

Development and validation of a simplified Stroke-Thrombolytic Predictive Instrument.

Neurology 2015 Sep 19;85(11):942-9. Epub 2015 Aug 19.

From the Predictive Analytics and Comparative Effectiveness Center (D.M.K., R.R.), Institute for Clinical Research and Health Policy Studies, Tufts Medical Center/Tufts University School of Medicine, Boston, MA; Saint Luke's Mid America Heart Institute (C.D., P.G.J., J.A.S.), Kansas City, MO; University of Missouri-Kansas City (C.D., P.G.J., J.A.S.); Stroke Center and Department of Neurology (J.L.S.), University of California, Los Angeles; and Boehringer Ingelheim (E.B.), Germany.

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http://dx.doi.org/10.1212/WNL.0000000000001925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567461PMC
September 2015

The RoPE Score and Right-to-Left Shunt Severity by Transcranial Doppler in the CODICIA Study.

Cerebrovasc Dis 2015 11;40(1-2):52-8. Epub 2015 Jul 11.

Division of Cardiology, Tufts Medical Center, Boston, Mass., USA.

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http://dx.doi.org/10.1159/000430998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523222PMC
May 2016

Clinical Prediction Models for Cardiovascular Disease: Tufts Predictive Analytics and Comparative Effectiveness Clinical Prediction Model Database.

Circ Cardiovasc Qual Outcomes 2015 Jul 7;8(4):368-75. Epub 2015 Jul 7.

From the Division of Cardiology, Tufts Medical Center, Boston, MA (B.S.W.); Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, Boston, MA (B.S.W., L.L.Y., J.S.L., D.M.K.); Business Intelligence and Analytics, Iora Health, Cambridge, MA (W.K.); Health Economics and Reimbursement, Boston Scientific, Marlborough, MA (M.C.); and Center for Clinical Evidence Synthesis, ICRHPS, Medical Center/Tufts University School of Medicine, Boston, MA (G.R.).

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http://dx.doi.org/10.1161/CIRCOUTCOMES.115.001693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512876PMC
July 2015

Prevention of recurrent stroke in patients with patent foramen ovale.

Neurol Clin 2015 May 28;33(2):491-500. Epub 2015 Feb 28.

Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Box 63, Boston, MA 02111, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ncl.2015.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409665PMC
May 2015

All else being equal, men and women are still not the same: using risk models to understand gender disparities in care.

Circ Cardiovasc Qual Outcomes 2015 May 21;8(3):317-20. Epub 2015 Apr 21.

From the Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA (J.K.P., D.M.K.); and Division of Health Care Policy and Research, Mayo Clinic, Rochester, MN (N.D.S.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440837PMC
May 2015

Multiple chronic conditions in type 2 diabetes mellitus: prevalence and consequences.

Am J Manag Care 2015 Jan 1;21(1):e23-34. Epub 2015 Jan 1.

Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, 800 Washington St, Box 63, Boston, MA 02111. E-mail:

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January 2015

Myocardial Infarction, Stroke, and Mortality in cART-Treated HIV Patients on Statins.

AIDS Patient Care STDS 2015 Jun 9;29(6):307-13. Epub 2015 Apr 9.

1Tufts Medical Center and Tufts University, Boston, Massachusetts.

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http://dx.doi.org/10.1089/apc.2014.0309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516911PMC
June 2015

Improving diabetes prevention with benefit based tailored treatment: risk based reanalysis of Diabetes Prevention Program.

BMJ 2015 Feb 19;350:h454. Epub 2015 Feb 19.

Department of Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI 48109-2800, USA Division of General Internal Medicine, University of Michigan, NCRC, 2800 Plymouth Road, Building 16/343E, Ann Arbor RWJ Foundation Clinical Scholars Program, University of Michigan, 2800 Plymouth Road, NCRC B10-G016, Ann Arbor.

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http://dx.doi.org/10.1136/bmj.h454DOI Listing
February 2015

Toward a modern era in clinical prediction: the TRIPOD statement for reporting prediction models.

Am J Kidney Dis 2015 Apr 15;65(4):530-3. Epub 2015 Jan 15.

Tufts Medical Center, Boston, Massachusetts.

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April 2015

Controversies in cardioembolic stroke.

Curr Treat Options Cardiovasc Med 2015 Jan;17(1):358

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies (ICRHPS), Tufts Medical Center/Tufts University School of Medicine, 800 Washington St, Box 63, Boston, MA, 02111, USA.

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http://dx.doi.org/10.1007/s11936-014-0358-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420158PMC
January 2015

Determinants of antithrombotic choice for patent foramen ovale in cryptogenic stroke.

Neurology 2014 Nov 22;83(21):1954-7. Epub 2014 Oct 22.

From the Department of Neurology (D.E.T., D.M.K.), and Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies (R.R., J.S.L., D.M.K.), Tufts Medical Center/Tufts University School of Medicine, Boston, MA; Department of Neurology, University of Duisburg-Essen (C.W.), Germany; Neurology Department at the Hospital Universitari Doctor Josep Trueta Institut d'Investigació Biomèdica de Girona (J.S.), Spain; Department of Neurology, Inselspital (H.P.M., M.-L.M.), University of Bern; Division of Neurology at the Triemli Municipal Hospital (K.N.), Zurich, Switzerland; Department of Public Health and Primary Care (E.D.A.), Cambridge University, UK; Departments of Neurology and Epidemiology (M.S.V.E.), and Division of Cardiology (M.R.D.T., S.H.), Columbia University, NY; Neurology Service, Centre Hospitalier Universitaire Vaudois (P.M.), Switzerland; Department of Cardiology (B.M.), Swiss Cardiovascular Center, Inselspital, University of Bern, Switzerland; and Department of Neurology (A.J.F.), Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1212/WNL.0000000000001007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248455PMC
November 2014

Can the learning health care system be educated with observational data?

JAMA 2014 Jul;312(2):129-30

Predictive Analytics and Comparative Effectiveness (PACE) Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2014.4364DOI Listing
July 2014

Recurrent stroke predictors differ in medically treated patients with pathogenic vs. other PFOs.

Neurology 2014 Jul 13;83(3):221-6. Epub 2014 Jun 13.

From the Department of Neurology (D.E.T., D.M.K.) and the Predictive Analytics and Comparative Effectiveness Center, Institute for Clinical Research and Health Policy Studies (R.R., J.S.L., J.G., D.M.K.), Tufts Medical Center/Tufts University School of Medicine, Boston, MA; the University of Duisburg-Essen (C.W.), Germany; Hôpital Sainte-Anne (J.L.-M.), Paris-Descartes University, France; the Department of Neurology (J.S.), Hospital Universitari Doctor Josep Trueta Institut d'Investigació Biomèdica de Girona, Spain; the Department of Public Health and Primary Care (E.D.A.), Cambridge University, UK; the Department of Cardiology (F.P.), Sapienza University of Rome, Italy; the Departments of Cardiology (S.H.) and Neurology and Epidemiology (M.S.V.E.) and the Division of Cardiology (M.R.D.T.), Columbia University, New York; Inselspital (H.P.M., M.-L.M.), University of Bern; the Division of Neurology (K.N.), Triemli Municipal Hospital, Zurich, Switzerland; the University of Toronto (C.J.), Canada; and Centre Hospitalier Universitaire Vaudois (P.M.), Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000000589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117365PMC
July 2014

Baseline characteristics predict risk of progression and response to combined medical therapy for benign prostatic hyperplasia (BPH).

BJU Int 2015 Feb 13;115(2):308-16. Epub 2014 Aug 13.

Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231026PMC
February 2015

A nomogram to predict major complications after hip and knee arthroplasty.

J Arthroplasty 2014 Jul 1;29(7):1457-62. Epub 2014 May 1.

Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.arth.2013.09.007DOI Listing
July 2014

Off-hour presentation and outcomes in patients with acute ischemic stroke: a systematic review and meta-analysis.

Eur J Intern Med 2014 Apr 12;25(4):394-400. Epub 2014 Apr 12.

Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2014.03.012DOI Listing
April 2014

Effects of chemotherapy on survival of elderly patients with small-cell lung cancer: analysis of the SEER-medicare database.

J Thorac Oncol 2013 Oct;8(10):1272-81

*Holy Family Hospital, Cancer Management Center, Methuen, Massachusetts; †Tufts Medical Center Institute for Clinical Research and Health Policy Studies, Boston, Massachusetts; and ‡Tufts Medical Center Division of Hematology/Oncology, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901951PMC
October 2013