David Lyden

David Lyden

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David Lyden

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Tumor Lymphatic Function Regulates Tumor Inflammatory and Immunosuppressive Microenvironments.

Cancer Immunol Res 2019 Aug 11;7(8):1345-1358. Epub 2019 Jun 11.

Department of Surgery, Plastic and Reconstructive Surgery Service, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677612PMC
August 2019

Tumour vesicular micromachinery uncovered.

Nat Cell Biol 2019 07;21(7):795-797

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41556-019-0351-0DOI Listing
July 2019

Exosome-Mediated Metastasis: Communication from a Distance.

Dev Cell 2019 05;49(3):347-360

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.04.011DOI Listing
May 2019

Asymmetric-flow field-flow fractionation technology for exomere and small extracellular vesicle separation and characterization.

Nat Protoc 2019 04 4;14(4):1027-1053. Epub 2019 Mar 4.

Children's Cancer and Blood Foundation Laboratories, Department of Pediatrics and Department of Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41596-019-0126-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733524PMC
April 2019

Tumor Extracellular Vesicles Impede Interferon Alert Responses.

Cancer Cell 2019 01;35(1):3-5

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.12.006DOI Listing
January 2019

Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.

PLoS One 2018 2;13(7):e0199012. Epub 2018 Jul 2.

Department of Pediatrics, and Cell and Developmental Biology Weill Medical College of Cornell University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199012PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028090PMC
December 2018

Engineered niches model the onset of metastasis.

Nat Biomed Eng 2018 12;2(12):885-887

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.

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http://dx.doi.org/10.1038/s41551-018-0326-7DOI Listing
December 2018

Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression.

Sci Adv 2018 02 28;4(2):eaao0665. Epub 2018 Feb 28.

Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.

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http://dx.doi.org/10.1126/sciadv.aao0665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829973PMC
February 2018

Bone voyage-Osteoblasts remotely control tumors.

Science 2017 12;358(6367):1127-1128

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.

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http://dx.doi.org/10.1126/science.aar2640DOI Listing
December 2017

A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.

Pediatr Blood Cancer 2017 Jul 30;64(7). Epub 2016 Dec 30.

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1002/pbc.26409DOI Listing
July 2017

Unshielding Exosomal RNA Unleashes Tumor Growth And Metastasis.

Cell 2017 07;170(2):223-225

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674173076
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http://dx.doi.org/10.1016/j.cell.2017.06.047DOI Listing
July 2017

Metastasis: Lymphatic detours for cancer.

Nature 2017 06;546(7660):609-610

Departments of Pediatrics, and of Cell and Developmental Biology, Weill Cornell Medicine, New York, New York 10021, USA.

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http://www.nature.com/doifinder/10.1038/546609a
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http://dx.doi.org/10.1038/546609aDOI Listing
June 2017

Pre-metastatic niches: organ-specific homes for metastases.

Nat Rev Cancer 2017 05 17;17(5):302-317. Epub 2017 Mar 17.

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nrc.2017.6DOI Listing
May 2017

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis.

Cancer Cell 2016 Dec;30(6):836-848

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/j.ccell.2016.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157696PMC
December 2016

Cancer Exosomes as Mediators of Drug Resistance.

Methods Mol Biol 2016 ;1395:229-39

Champalimaud Foundation, Lisbon, Portugal.

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http://dx.doi.org/10.1007/978-1-4939-3347-1_13DOI Listing
November 2016

Pre-Metastatic Niche Formation Has Taken Its TOLL.

Cancer Cell 2016 08;30(2):189-191

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.07.012DOI Listing
August 2016

Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.

Authors:
Eric M Thompson Thomas Hielscher Eric Bouffet Marc Remke Betty Luu Sridharan Gururangan Roger E McLendon Darell D Bigner Eric S Lipp Sebastien Perreault Yoon-Jae Cho Gerald Grant Seung-Ki Kim Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Kay Ka Wai Li Ho-Keung Ng Yu Yao Toshihiro Kumabe Teiji Tominaga Wieslawa A Grajkowska Marta Perek-Polnik David C Y Low Wan Tew Seow Kenneth T E Chang Jaume Mora Ian F Pollack Ronald L Hamilton Sarah Leary Andrew S Moore Wendy J Ingram Andrew R Hallahan Anne Jouvet Michelle Fèvre-Montange Alexandre Vasiljevic Cecile Faure-Conter Tomoko Shofuda Naoki Kagawa Naoya Hashimoto Nada Jabado Alexander G Weil Tenzin Gayden Takafumi Wataya Tarek Shalaby Michael Grotzer Karel Zitterbart Jaroslav Sterba Leos Kren Tibor Hortobágyi Almos Klekner Bognár László Tímea Pócza Peter Hauser Ulrich Schüller Shin Jung Woo-Youl Jang Pim J French Johan M Kros Marie-Lise C van Veelen Luca Massimi Jeffrey R Leonard Joshua B Rubin Rajeev Vibhakar Lola B Chambless Michael K Cooper Reid C Thompson Claudia C Faria Alice Carvalho Sofia Nunes José Pimentel Xing Fan Karin M Muraszko Enrique López-Aguilar David Lyden Livia Garzia David J H Shih Noriyuki Kijima Christian Schneider Jennifer Adamski Paul A Northcott Marcel Kool David T W Jones Jennifer A Chan Ana Nikolic Maria Luisa Garre Erwin G Van Meir Satoru Osuka Jeffrey J Olson Arman Jahangiri Brandyn A Castro Nalin Gupta William A Weiss Iska Moxon-Emre Donald J Mabbott Alvaro Lassaletta Cynthia E Hawkins Uri Tabori James Drake Abhaya Kulkarni Peter Dirks James T Rutka Andrey Korshunov Stefan M Pfister Roger J Packer Vijay Ramaswamy Michael D Taylor

Lancet Oncol 2016 04 12;17(4):484-495. Epub 2016 Mar 12.

Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045150058
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http://dx.doi.org/10.1016/S1470-2045(15)00581-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907853PMC
April 2016

Divergent clonal selection dominates medulloblastoma at recurrence.

Authors:
A Sorana Morrissy Livia Garzia David J H Shih Scott Zuyderduyn Xi Huang Patryk Skowron Marc Remke Florence M G Cavalli Vijay Ramaswamy Patricia E Lindsay Salomeh Jelveh Laura K Donovan Xin Wang Betty Luu Kory Zayne Yisu Li Chelsea Mayoh Nina Thiessen Eloi Mercier Karen L Mungall Yusanne Ma Kane Tse Thomas Zeng Karey Shumansky Andrew J L Roth Sohrab Shah Hamza Farooq Noriyuki Kijima Borja L Holgado John J Y Lee Stuart Matan-Lithwick Jessica Liu Stephen C Mack Alex Manno K A Michealraj Carolina Nor John Peacock Lei Qin Juri Reimand Adi Rolider Yuan Y Thompson Xiaochong Wu Trevor Pugh Adrian Ally Mikhail Bilenky Yaron S N Butterfield Rebecca Carlsen Young Cheng Eric Chuah Richard D Corbett Noreen Dhalla An He Darlene Lee Haiyan I Li William Long Michael Mayo Patrick Plettner Jenny Q Qian Jacqueline E Schein Angela Tam Tina Wong Inanc Birol Yongjun Zhao Claudia C Faria José Pimentel Sofia Nunes Tarek Shalaby Michael Grotzer Ian F Pollack Ronald L Hamilton Xiao-Nan Li Anne E Bendel Daniel W Fults Andrew W Walter Toshihiro Kumabe Teiji Tominaga V Peter Collins Yoon-Jae Cho Caitlin Hoffman David Lyden Jeffrey H Wisoff James H Garvin Duncan S Stearns Luca Massimi Ulrich Schüller Jaroslav Sterba Karel Zitterbart Stephanie Puget Olivier Ayrault Sandra E Dunn Daniela P C Tirapelli Carlos G Carlotti Helen Wheeler Andrew R Hallahan Wendy Ingram Tobey J MacDonald Jeffrey J Olson Erwin G Van Meir Ji-Yeoun Lee Kyu-Chang Wang Seung-Ki Kim Byung-Kyu Cho Torsten Pietsch Gudrun Fleischhack Stephan Tippelt Young Shin Ra Simon Bailey Janet C Lindsey Steven C Clifford Charles G Eberhart Michael K Cooper Roger J Packer Maura Massimino Maria Luisa Garre Ute Bartels Uri Tabori Cynthia E Hawkins Peter Dirks Eric Bouffet James T Rutka Robert J Wechsler-Reya William A Weiss Lara S Collier Adam J Dupuy Andrey Korshunov David T W Jones Marcel Kool Paul A Northcott Stefan M Pfister David A Largaespada Andrew J Mungall Richard A Moore Nada Jabado Gary D Bader Steven J M Jones David Malkin Marco A Marra Michael D Taylor

Nature 2016 Jan 13;529(7586):351-7. Epub 2016 Jan 13.

Developmental &Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

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http://dx.doi.org/10.1038/nature16478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936195PMC
January 2016

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.

Nat Cell Biol 2015 Jun 18;17(6):816-26. Epub 2015 May 18.

1] Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medical College, New York, New York 10021, USA [2] Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/ncb3169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769922PMC
June 2015

Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.

Nat Commun 2015 Apr 29;6:6840. Epub 2015 Apr 29.

1] Children's Cancer and Blood Foundation Laboratories and Departments of Pediatrics and Cell and Developmental Biology, Weill Cornell Medical College, 413 East 69th Street, New York City, New York 10021, USA [2] Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York City, New York 10065, USA.

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http://dx.doi.org/10.1038/ncomms7840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423225PMC
April 2015

Macromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine.

Adv Mater 2014 May 6;26(19):3024-34. Epub 2014 Feb 6.

Network of Excellence for Functional Biomaterials (NFB), National University of Ireland Galway, (NUI Galway), Galway, Ireland.

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http://dx.doi.org/10.1002/adma.201304428DOI Listing
May 2014

Oligodendrocyte progenitor cells promote neovascularization in glioma by disrupting the blood-brain barrier.

Cancer Res 2014 Feb 26;74(4):1011-21. Epub 2013 Dec 26.

Authors' Affiliations: Department of Neurological Surgery, The Childhood Brain Tumor Project; Department of Pediatrics; Division of Hematology-Medical Oncology; Pediatric Brain Tumor Research, Children's Cancer and Blood Foundation Laboratories, Weill Cornell Medical College; Departments of Pathology and Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York; and National Eye Institute, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1072DOI Listing
February 2014

Roadblocks to translational advances on metastasis research.

Nat Med 2013 Sep;19(9):1104-9

1] Department of General and Visceral Surgery, Comprehensive Cancer Center and BIOSS Centre for Biological Signalling Studies, University of Freiburg Medical Center, Freiburg, Germany. [2].

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http://dx.doi.org/10.1038/nm.3327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972758PMC
September 2013

The perivascular niche regulates breast tumour dormancy.

Nat Cell Biol 2013 Jul 2;15(7):807-17. Epub 2013 Jun 2.

Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1038/ncb2767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826912PMC
July 2013

The evolution of the cancer niche during multistage carcinogenesis.

Nat Rev Cancer 2013 07 13;13(7):511-8. Epub 2013 Jun 13.

The Department of Radiation Oncology, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1038/nrc3536DOI Listing
July 2013

Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes.

Mol Biol Cell 2013 Jun 10;24(11):1619-37, S1-3. Epub 2013 Apr 10.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, New York, NY 10461, USA.

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http://dx.doi.org/10.1091/mbc.E12-07-0544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667717PMC
June 2013

Molecular diagnostics in paediatric glial tumours.

Lancet Oncol 2013 Jan;14(1):e19-27

Department of Neurological Surgery, Weill Cornell Medical College, New York, NY 10065, USA.

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470204512
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http://linkinghub.elsevier.com/retrieve/pii/S147020451270577
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http://dx.doi.org/10.1016/S1470-2045(12)70577-6DOI Listing
January 2013

STAT3 negatively regulates thyroid tumorigenesis.

Proc Natl Acad Sci U S A 2012 Aug 13;109(35):E2361-70. Epub 2012 Aug 13.

Department of Cancer Biology, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), 4200-465 Porto, Portugal.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1201232109
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http://dx.doi.org/10.1073/pnas.1201232109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435219PMC
August 2012

Disease control and ototoxicity using intensity-modulated radiation therapy tumor-bed boost for medulloblastoma.

Int J Radiat Oncol Biol Phys 2011 Nov 12;81(3):e15-20. Epub 2011 Apr 12.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2010.11.081DOI Listing
November 2011

A TeNaCious foundation for the metastatic niche.

Cancer Cell 2011 Aug;20(2):139-41

Departments of Pediatrics and Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.08.004DOI Listing
August 2011

The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.

Semin Cancer Biol 2011 Apr 18;21(2):139-46. Epub 2011 Jan 18.

Department of Pediatrics, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.semcancer.2011.01.002DOI Listing
April 2011

Neoangiogenesis contributes to the development of hemophilic synovitis.

Blood 2011 Feb 16;117(8):2484-93. Epub 2010 Dec 16.

Department of Pediatric Hematology/Oncology, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1182/blood-2010-05-284653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317791PMC
February 2011

Intensive multimodality therapy for patients with stage 4a metastatic retinoblastoma.

Pediatr Blood Cancer 2010 Jul;55(1):55-9

Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1002/pbc.22504DOI Listing
July 2010

Resisting arrest: a switch from angiogenesis to vasculogenesis in recurrent malignant gliomas.

J Clin Invest 2010 Mar 22;120(3):663-7. Epub 2010 Feb 22.

Pediatric Brain Tumor Research and Children's Cancer and Blood Foundation Laboratories, Champalimaud Metastasis Programme, New York, New York, USA.

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http://dx.doi.org/10.1172/JCI42345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827970PMC
March 2010

Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent.

Nat Biotechnol 2010 Feb 17;28(2):161-6. Epub 2010 Jan 17.

Howard Hughes Medical Institute, Ansary Stem Cell Institute, Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, USA.

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http://dx.doi.org/10.1038/nbt.1605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931334PMC
February 2010

Gene therapy in skin: choosing the optimal viral vector.

Ann Plast Surg 2009 May;62(5):576-80

Division of Plastic and Reconstructive Surgery, New York Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1097/SAP.0b013e31819fafbdDOI Listing
May 2009

The metastatic niche: adapting the foreign soil.

Nat Rev Cancer 2009 04;9(4):285-93

Department of Pediatrics, Weill Cornell Medical College, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nrc2621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682494PMC
April 2009

A novel method for targeted gene therapy in ischemic tissues through viral transfection of an expression cassette containing multiple repetitions of hypoxia response element.

Plast Reconstr Surg 2009 Feb;123(2 Suppl):76S-82S

Division of Plastic Surgery, Department of Pediatrics, Children's Blood Foundation Laboratories, Cornell University Medical College, New York, NY, USA.

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http://dx.doi.org/10.1097/PRS.0b013e318191c044DOI Listing
February 2009

Chapter 11. The role of bone marrow-derived cells in tumor angiogenesis and metastatic progression.

Methods Enzymol 2008 ;444:255-69

Department of Pediatrics and Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, USA.

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http://dx.doi.org/10.1016/S0076-6879(08)02811-5DOI Listing
January 2009

Inflammation joins the "niche".

Cancer Cell 2008 Nov;14(5):347-9

Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.ccr.2008.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951628PMC
November 2008

Migratory neighbors and distant invaders: tumor-associated niche cells.

Genes Dev 2008 Mar;22(5):559-74

Department of Pediatrics, Weill Cornell Medical College, New York, NY 10021, USA.

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http://dx.doi.org/10.1101/gad.1636908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731657PMC
March 2008

A catalytic role for proangiogenic marrow-derived cells in tumor neovascularization.

Cancer Cell 2008 Mar;13(3):181-3

Howard Hughes Medical Institute, Ansary Center for Stem Cell Therapeutics, Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561080800052
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http://dx.doi.org/10.1016/j.ccr.2008.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951026PMC
March 2008

Regulation of vasculogenesis by platelet-mediated recruitment of bone marrow-derived cells.

Arterioscler Thromb Vasc Biol 2008 Feb 20;28(2):217-22. Epub 2007 Dec 20.

Weill Cornell Medical College, Department of Pediatrics, New York, NY 10021, USA.

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http://dx.doi.org/10.1161/ATVBAHA.107.151159DOI Listing
February 2008

Cancer. A few to flip the angiogenic switch.

Science 2008 Jan;319(5860):163-4

Howard Hughes Medical Institute, Weill Cornell Medical College, New York, NY 10065, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1153615
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http://dx.doi.org/10.1126/science.1153615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951621PMC
January 2008

A phase II trial of carboplatin for intraocular retinoblastoma.

Pediatr Blood Cancer 2007 Oct;49(5):643-8

Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1002/pbc.21163DOI Listing
October 2007

Priming the 'soil' for breast cancer metastasis: the pre-metastatic niche.

Breast Dis 2006-2007;26:65-74

Department of Pediatrics, Weill College of Medicine at Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.3233/bd-2007-26106DOI Listing
July 2007

Niche-to-niche migration of bone-marrow-derived cells.

Trends Mol Med 2007 Feb 2;13(2):72-81. Epub 2007 Jan 2.

Department of Pediatrics, Weill College of Medicine at Cornell University and Memorial Sloan-Kettering Cancer Center, New York, NY10021, USA.

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http://dx.doi.org/10.1016/j.molmed.2006.12.003DOI Listing
February 2007

Preparing the "soil": the premetastatic niche.

Cancer Res 2006 Dec;66(23):11089-93

Department of Pediatrics, Weill College of Medicine at Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-2407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952469PMC
December 2006

Bone marrow cells in the 'pre-metastatic niche': within bone and beyond.

Cancer Metastasis Rev 2006 Dec;25(4):521-9

Department of Pediatrics, Cell and Developmental Biology, Weill College of Medicine at Cornell University, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1007/s10555-006-9036-9DOI Listing
December 2006

AC133/CD133/Prominin-1.

Int J Biochem Cell Biol 2005 Apr;37(4):715-9

Weill Medical College of Cornell University, Department of Genetic Medicine, 1300 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.biocel.2004.08.010DOI Listing
April 2005

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.

Nat Med 2004 Jan 21;10(1):64-71. Epub 2003 Dec 21.

Department of Medicine, Division of Hematology-Oncology, Cornell University Medical College, 1300 York Avenue, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nm973DOI Listing
January 2004

Patterns of failure using a conformal radiation therapy tumor bed boost for medulloblastoma.

J Clin Oncol 2003 Aug;21(16):3079-83

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, Box 22, New York, NY 10021, USA.

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http://dx.doi.org/10.1200/JCO.2003.11.140DOI Listing
August 2003

Primary leptomeningeal primitive neuroectodermal tumor.

J Neurooncol 2003 Jul;63(3):299-303

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1023/a:1024324700411DOI Listing
July 2003

Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration.

Nat Med 2003 Jun;9(6):702-12

Department of Hematology-Oncology and Genetic Medicine, Cornell University Medical College, New York, New York, 10021 USA.

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http://www.nature.com/articles/nm0603-702
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http://dx.doi.org/10.1038/nm0603-702DOI Listing
June 2003

Tumor response to radiotherapy regulated by endothelial cell apoptosis.

Science 2003 May;300(5622):1155-9

Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1126/science.1082504DOI Listing
May 2003

Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?

Nat Rev Cancer 2002 Nov;2(11):826-35

Division of Hematology-Oncology, Cornell University Medical College, 1300 York Avenue, Room D601, New York, New York 10021, USA.

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http://www.nature.com/articles/nrc925
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http://dx.doi.org/10.1038/nrc925DOI Listing
November 2002

Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function.

Circ Res 2002 May;90(10):E89-93

Department of Medicine, Weill Medical College of Cornell University, New York, NY, USA.

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http://dx.doi.org/10.1161/01.res.0000020861.20064.7eDOI Listing
May 2002

Contribution of marrow-derived progenitors to vascular and cardiac regeneration.

Semin Cell Dev Biol 2002 Feb;13(1):61-7

Cornell University Medical College, New York, USA.

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http://dx.doi.org/10.1006/scdb.2001.0285DOI Listing
February 2002

Epstein-Barr virus-associated lymphoma in a child undergoing an autologous stem cell rescue.

J Pediatr Hematol Oncol 2002 Feb;24(2):160-3

Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1097/00043426-200202000-00022DOI Listing
February 2002