David Little

David Little

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David Little

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The Effect of an Asymmetric Energy Window on Bone Scintigraphy Image Quality.

J Nucl Med Technol 2020 Mar 11;48(1):46-50. Epub 2019 Oct 11.

Nuclear Medicine Department, Royal United Hospitals Bath, Combe Park, Avon, United Kingdom; and

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http://tech.snmjournals.org/lookup/doi/10.2967/jnmt.119.2335
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http://dx.doi.org/10.2967/jnmt.119.233577DOI Listing
March 2020

Increased anabolic bone response in Dkk1 KO mice following tibial compressive loading.

Bone 2020 Feb 12;131:115054. Epub 2019 Sep 12.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Sydney, Australia; Discipline of Child and Adolescent Health, Sydney Medical School, University of Sydney, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.115054DOI Listing
February 2020

Pretreatment with Pamidronate Decreases Bone Formation but Increases Callus Bone Volume in a Rat Closed Fracture Model.

Calcif Tissue Int 2020 Feb 1;106(2):172-179. Epub 2019 Oct 1.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1007/s00223-019-00615-zDOI Listing
February 2020

CSA-90 reduces periprosthetic joint infection in a novel rat model challenged with local and systemic Staphylococcus aureus.

J Orthop Res 2020 Feb 3. Epub 2020 Feb 3.

Department of Orthopaedic Research and Biotechnology, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.

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http://dx.doi.org/10.1002/jor.24618DOI Listing
February 2020

The application of ceragenins to orthopedic surgery and medicine.

J Orthop Res 2020 Jan 29. Epub 2020 Jan 29.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Sydney, NSW, Australia.

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http://dx.doi.org/10.1002/jor.24615DOI Listing
January 2020

Targeting Adeno-Associated Virus Vectors for Local Delivery to Fractures and Systemic Delivery to the Skeleton.

Mol Ther Methods Clin Dev 2019 Dec 5;15:101-111. Epub 2019 Sep 5.

Orthopaedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Westmead, NSW, Australia.

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http://dx.doi.org/10.1016/j.omtm.2019.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804917PMC
December 2019

Image quality improvement for medium and large field of view Elekta XVI scans.

Authors:
David P Little

Australas Phys Eng Sci Med 2019 Dec 14;42(4):1153-1164. Epub 2019 Nov 14.

Canterbury District Health Board, Christchurch Hospital, 2 Riccarton Road, Christchurch, 8011, New Zealand.

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http://dx.doi.org/10.1007/s13246-019-00817-7DOI Listing
December 2019

A Bioactive Coating Enhances Bone Allografts in Rat Models of Bone Formation and Critical Defect Repair.

J Orthop Res 2019 11 17;37(11):2278-2286. Epub 2019 Jul 17.

Orthopaedic Research and Biotechnology, Children's Hospital at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1002/jor.24409DOI Listing
November 2019

Parathyroid scintigraphy.

Nucl Med Commun 2019 Sep;40(9):e1-e3

Royal United Hospitals, Bath.

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http://dx.doi.org/10.1097/MNM.0000000000001067DOI Listing
September 2019

Current Challenges and Emergent Technologies for Manufacturing Artificial Right Ventricle to Pulmonary Artery (RV-PA) Cardiac Conduits.

Cardiovasc Eng Technol 2019 06 14;10(2):205-215. Epub 2019 Feb 14.

The Heart Centre for Children, The Children's Hospital at Westmead, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1007/s13239-019-00406-5DOI Listing
June 2019

Semi-supervised learning of a nonnative phonetic contrast: How much feedback is enough?

Atten Percept Psychophys 2019 May;81(4):927-934

Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, USA.

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http://link.springer.com/10.3758/s13414-019-01741-4
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http://dx.doi.org/10.3758/s13414-019-01741-4DOI Listing
May 2019

Bone Marrow Transplantation for Treatment of the Col1a2 Osteogenesis Imperfecta Mouse Model.

Calcif Tissue Int 2019 04 8;104(4):426-436. Epub 2018 Dec 8.

Orthopaedic Research and Biotechnology Unit, Kids Research, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1007/s00223-018-0504-3DOI Listing
April 2019

Will fish be part of future healthy and sustainable diets?

Lancet Planet Health 2019 Apr;3(4):e159-e160

Commonwealth Scientific and Industrial Research Organisation, Agriculture and Food, Brisbane, QLD 4067, Australia.

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http://dx.doi.org/10.1016/S2542-5196(19)30018-XDOI Listing
April 2019

Effect of rapamycin on bone mass and strength in the α2(I)-G610C mouse model of osteogenesis imperfecta.

J Cell Mol Med 2019 03 30;23(3):1735-1745. Epub 2018 Dec 30.

Orthopaedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/jcmm.14072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378195PMC
March 2019

Inducing musical-interval learning by combining task practice with periods of stimulus exposure alone.

Atten Percept Psychophys 2019 Jan;81(1):344-357

Communication Sciences and Disorders, Knowles Hearing Center, Northwestern Institute for Neuroscience, Northwestern University, Evanston, IL, 60208-3550, USA.

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http://link.springer.com/10.3758/s13414-018-1584-x
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http://dx.doi.org/10.3758/s13414-018-1584-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384134PMC
January 2019

Optimized Synthesis of Poly(deoxyribose) Isobutyrate, a Viscous Biomaterial for Bone Morphogenetic Protein-2 Delivery.

ACS Appl Mater Interfaces 2019 Jan 11;11(3):2870-2879. Epub 2019 Jan 11.

School of Chemical and Biomolecular Engineering , The University of Sydney , Sydney 2006 , Australia.

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http://dx.doi.org/10.1021/acsami.8b20126DOI Listing
January 2019

Lipid storage myopathies: Current treatments and future directions.

Prog Lipid Res 2018 10 9;72:1-17. Epub 2018 Aug 9.

Orthopaedic Research & Biotechnology, The Children's Hospital at Westmead, Westmead, NSW, Australia.; Discipline of Paediatrics & Child Heath, Faculty of Medicine, University of Sydney, Camperdown, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2018.08.001DOI Listing
October 2018

Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume.

Calcif Tissue Int 2018 09 29;103(3):298-310. Epub 2018 May 29.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1007/s00223-018-0420-6DOI Listing
September 2018

Limitations of the Pax7-creER transgene for driving deletion of Nf1 in adult mouse muscle.

Int J Dev Biol 2017 ;61(8-9):531-536

Orthopaedic Research and Biotechnology, The Children's Hospital at Westmead, Westmead, NSW, Australia.

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http://dx.doi.org/10.1387/ijdb.170182asDOI Listing
July 2018

CSA-90 Promotes Bone Formation and Mitigates Methicillin-resistant Staphylococcus aureus Infection in a Rat Open Fracture Model.

Clin Orthop Relat Res 2018 06;476(6):1311-1323

R. Mills, T. L. Cheng, K. Mikulec, L. Peacock, D. G. Little, A. Schindeler, Orthopedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Sydney, Australia T. L. Cheng, D. Isaacs, D. G. Little, A. Schindeler, Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia D. Isaacs, Department of Infectious Diseases & Microbiology, Children's Hospital at Westmead, Westmead, NSW, Australia C. Genberg, N8 Medical, Dublin, OH, USA P. B. Savage, Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT, USA.

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http://dx.doi.org/10.1097/01.blo.0000533624.79802.e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263573PMC
June 2018

Sclerostin antibody enhances bone formation in a rat model of distraction osteogenesis.

J Orthop Res 2018 04 1;36(4):1106-1113. Epub 2018 Feb 1.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, New South Wales 2145, Sydney, Australia.

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http://doi.wiley.com/10.1002/jor.23726
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http://dx.doi.org/10.1002/jor.23726DOI Listing
April 2018

Developmental dosing with a MEK inhibitor (PD0325901) rescues myopathic features of the muscle-specific but not limb-specific Nf1 knockout mouse.

Mol Genet Metab 2018 04 16;123(4):518-525. Epub 2018 Feb 16.

Orthopaedic Research & Biotechnology, The Children's Hospital at Westmead, Westmead, NSW, Australia; Discipline of Paediatrics & Child Heath, Faculty of Medicine, University of Sydney, Camperdown, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2018.02.009DOI Listing
April 2018

Improved union and bone strength in a mouse model of NF1 pseudarthrosis treated with recombinant human bone morphogenetic protein-2 and zoledronic acid.

J Orthop Res 2018 03 4;36(3):930-936. Epub 2017 Oct 4.

Orthopaedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, Sydney, New South Wales, 2145, Australia.

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http://doi.wiley.com/10.1002/jor.23672
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http://dx.doi.org/10.1002/jor.23672DOI Listing
March 2018

Sclerostin Antibody Augments the Anabolic Bone Formation Response in a Mouse Model of Mechanical Tibial Loading.

J Bone Miner Res 2018 03 29;33(3):486-498. Epub 2017 Nov 29.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Westmead, Australia.

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http://dx.doi.org/10.1002/jbmr.3330DOI Listing
March 2018

Preclinical models for orthopedic research and bone tissue engineering.

J Orthop Res 2018 03 19;36(3):832-840. Epub 2017 Dec 19.

Orthopedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, Sydney, New South Wales, 2145, Australia.

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http://dx.doi.org/10.1002/jor.23824DOI Listing
March 2018

Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation.

Calcif Tissue Int 2018 01 6;102(1):105-116. Epub 2017 Nov 6.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Research Building, Locked Bag 4001, Westmead, NSW, 2145, Australia.

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http://link.springer.com/10.1007/s00223-017-0338-4
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http://dx.doi.org/10.1007/s00223-017-0338-4DOI Listing
January 2018

Multidisciplinary team and clinical meeting data: JRF national survey of trainees 2015.

Br J Radiol 2017 Dec 13;90(1080):20170156. Epub 2017 Sep 13.

7 Gastrointestinal Imaging Group, Department of Radiology, Consultant Radiologist, University Hospitals of Leicester , Leicester , UK.

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http://www.birpublications.org/doi/10.1259/bjr.20170156
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http://dx.doi.org/10.1259/bjr.20170156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047659PMC
December 2017

Disruption of Perceptual Learning by a Brief Practice Break.

Curr Biol 2017 Dec 22;27(23):3699-3705.e3. Epub 2017 Nov 22.

Department of Communication Sciences and Disorders, Knowles Hearing Center, Northwestern Institute for Neuroscience, Northwestern University, Evanston, IL 60208-3550, USA.

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http://dx.doi.org/10.1016/j.cub.2017.10.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848209PMC
December 2017

Guided Growth: Current Perspectives and Future Challenges.

JBJS Rev 2017 11;5(11):e1

Orthopaedic Research and Biotechnology, Kids Research Institute, Westmead, New South Wales, Australia.

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http://dx.doi.org/10.2106/JBJS.RVW.16.00115DOI Listing
November 2017

Sclerostin Antibody Increases Callus Size and Strength but does not Improve Fracture Union in a Challenged Open Rat Fracture Model.

Calcif Tissue Int 2017 08 8;101(2):217-228. Epub 2017 Apr 8.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Westmead, Australia.

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http://dx.doi.org/10.1007/s00223-017-0275-2DOI Listing
August 2017

Combination sclerostin antibody and zoledronic acid treatment outperforms either treatment alone in a mouse model of osteogenesis imperfecta.

Bone 2017 Aug 29;101:96-103. Epub 2017 Apr 29.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.bone.2017.04.016DOI Listing
August 2017

Fabrication of a Biodegradable Implant with Tunable Characteristics for Bone Implant Applications.

Biomacromolecules 2017 Jun 23;18(6):1736-1746. Epub 2017 May 23.

The University of Sydney , School of Chemical and Biomolecular Engineering, Sydney, 2006, Australia.

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http://dx.doi.org/10.1021/acs.biomac.7b00078DOI Listing
June 2017

Computational modelling of bone fracture healing under partial weight-bearing exercise.

Med Eng Phys 2017 04 22;42:65-72. Epub 2017 Feb 22.

Shenzhen Nanao People's Hospital, Shenzhen, Guangdong 518121, P R China. Electronic address:

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http://dx.doi.org/10.1016/j.medengphy.2017.01.025DOI Listing
April 2017

Local co-delivery of rhBMP-2 and cathepsin K inhibitor L006235 in poly(d,l-lactide-co-glycolide) nanospheres.

J Biomed Mater Res B Appl Biomater 2017 01 5;105(1):136-144. Epub 2015 Oct 5.

Department of Orthopaedic Research & Biotechnology, Kids Research Institute at The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1002/jbm.b.33481DOI Listing
January 2017

Can transcutaneous near infrared spectroscopy detect severe hepatic ischemia: a juvenile porcine model.

Paediatr Anaesth 2016 Dec 24;26(12):1188-1196. Epub 2016 Sep 24.

Discipline of Pediatrics and Child Health, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1111/pan.13004DOI Listing
December 2016

Effect of combined treatment with zoledronic acid and parathyroid hormone on mouse bone callus structure and composition.

Bone 2016 11 16;92:70-78. Epub 2016 Aug 16.

Institute for Biomechanics, HCP H 22.1, Leopold-Ruzicka-Weg 4, ETH Zurich, 8093 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.08.012DOI Listing
November 2016

Aquaculture: Are farmed fish just for the wealthy?

Nature 2016 10;538(7624):171

University of Stirling, UK.

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http://dx.doi.org/10.1038/538171dDOI Listing
October 2016

Biomechanics of Slipped Capital Femoral Epiphysis: Evaluation of the Posterior Sloping Angle.

J Pediatr Orthop 2016 Sep;36(6):651-5

Department of Orthopaedic Research & Biotechnology, Kids Research Institute, The Children's Hospital at Westmead, Westmead, NSW, Australia.

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http://dx.doi.org/10.1097/BPO.0000000000000512DOI Listing
September 2016

BMP-2 delivered via sucrose acetate isobutyrate (SAIB) improves bone repair in a rat open fracture model.

J Orthop Res 2016 07 8;34(7):1168-76. Epub 2016 Jan 8.

Orthopaedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, Sydney, New South Wales, 2145, Australia.

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http://dx.doi.org/10.1002/jor.23131DOI Listing
July 2016

Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.

J Med Chem 2016 07 17;59(13):6027-44. Epub 2016 Jun 17.

Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947980PMC
July 2016

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Authors:
Wesley C Van Voorhis John H Adams Roberto Adelfio Vida Ahyong Myles H Akabas Pietro Alano Aintzane Alday Yesmalie Alemán Resto Aishah Alsibaee Ainhoa Alzualde Katherine T Andrews Simon V Avery Vicky M Avery Lawrence Ayong Mark Baker Stephen Baker Choukri Ben Mamoun Sangeeta Bhatia Quentin Bickle Lotfi Bounaadja Tana Bowling Jürgen Bosch Lauren E Boucher Fabrice F Boyom Jose Brea Marian Brennan Audrey Burton Conor R Caffrey Grazia Camarda Manuela Carrasquilla Dee Carter Maria Belen Cassera Ken Chih-Chien Cheng Worathad Chindaudomsate Anthony Chubb Beatrice L Colon Daisy D Colón-López Yolanda Corbett Gregory J Crowther Noemi Cowan Sarah D'Alessandro Na Le Dang Michael Delves Joseph L DeRisi Alan Y Du Sandra Duffy Shimaa Abd El-Salam El-Sayed Michael T Ferdig José A Fernández Robledo David A Fidock Isabelle Florent Patrick V T Fokou Ani Galstian Francisco Javier Gamo Suzanne Gokool Ben Gold Todd Golub Gregory M Goldgof Rajarshi Guha W Armand Guiguemde Nil Gural R Kiplin Guy Michael A E Hansen Kirsten K Hanson Andrew Hemphill Rob Hooft van Huijsduijnen Takaaki Horii Paul Horrocks Tyler B Hughes Christopher Huston Ikuo Igarashi Katrin Ingram-Sieber Maurice A Itoe Ajit Jadhav Amornrat Naranuntarat Jensen Laran T Jensen Rays H Y Jiang Annette Kaiser Jennifer Keiser Thomas Ketas Sebastien Kicka Sunyoung Kim Kiaran Kirk Vidya P Kumar Dennis E Kyle Maria Jose Lafuente Scott Landfear Nathan Lee Sukjun Lee Adele M Lehane Fengwu Li David Little Liqiong Liu Manuel Llinás Maria I Loza Aristea Lubar Leonardo Lucantoni Isabelle Lucet Louis Maes Dalu Mancama Nuha R Mansour Sandra March Sheena McGowan Iset Medina Vera Stephan Meister Luke Mercer Jordi Mestres Alvine N Mfopa Raj N Misra Seunghyun Moon John P Moore Francielly Morais Rodrigues da Costa Joachim Müller Arantza Muriana Stephen Nakazawa Hewitt Bakela Nare Carl Nathan Nathalie Narraidoo Sujeevi Nawaratna Kayode K Ojo Diana Ortiz Gordana Panic George Papadatos Silvia Parapini Kailash Patra Ngoc Pham Sarah Prats David M Plouffe Sally-Ann Poulsen Anupam Pradhan Celia Quevedo Ronald J Quinn Christopher A Rice Mohamed Abdo Rizk Andrea Ruecker Robert St Onge Rafaela Salgado Ferreira Jasmeet Samra Natalie G Robinett Ulrich Schlecht Marjorie Schmitt Filipe Silva Villela Francesco Silvestrini Robert Sinden Dennis A Smith Thierry Soldati Andreas Spitzmüller Serge Maximilian Stamm David J Sullivan William Sullivan Sundari Suresh Brian M Suzuki Yo Suzuki S Joshua Swamidass Donatella Taramelli Lauve R Y Tchokouaha Anjo Theron David Thomas Kathryn F Tonissen Simon Townson Abhai K Tripathi Valentin Trofimov Kenneth O Udenze Imran Ullah Cindy Vallieres Edgar Vigil Joseph M Vinetz Phat Voong Vinh Hoan Vu Nao-Aki Watanabe Kate Weatherby Pamela M White Andrew F Wilks Elizabeth A Winzeler Edward Wojcik Melanie Wree Wesley Wu Naoaki Yokoyama Paul H A Zollo Nada Abla Benjamin Blasco Jeremy Burrows Benoît Laleu Didier Leroy Thomas Spangenberg Timothy Wells Paul A Willis

PLoS Pathog 2016 07 28;12(7):e1005763. Epub 2016 Jul 28.

Medicines for Malaria Venture, Geneva, Switzerland.

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http://dx.doi.org/10.1371/journal.ppat.1005763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965013PMC
July 2016

The Pathogenesis and Treatment of Legg-Calvé-Perthes Disease.

JBJS Rev 2016 07;4(7)

1Orthopaedic Research and Biotechnology, Department of Orthopaedic Surgery, Children's Hospital at Westmead, Sydney, Australia2Department of Orthopaedic Surgery, Hamad General Hospital, Doha, Qatar.

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http://dx.doi.org/10.2106/JBJS.RVW.15.00063DOI Listing
July 2016

Using an Integrated Digital Approach to Treatment Planning.

Authors:
David Little

Dent Today 2016 Jul;35(7):112-6

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July 2016

Today's Solutions for Edentulous Patients: Implants, Digital Dentures, and Streamlined Technologies.

Authors:
David Little

Compend Contin Educ Dent 2016 Jun;38(6):408-410

Private Practice, Professionals in Dentistry,San Antonio, Texas; Adjunct Clinical Professor, UT Health San Antonio, School of Dentistry, San Antonio, Texas.

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June 2016

Incidence and outcome of osteonecrosis in children and adolescents after intensive therapy for acute lymphoblastic leukemia (ALL).

Cancer Med 2016 05 20;5(5):960-7. Epub 2016 Jan 20.

Department of Endocrinology, The Children's Hospital at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1002/cam4.645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864825PMC
May 2016

RAP-011 augments callus formation in closed fractures in rats.

J Orthop Res 2016 Feb 1;34(2):320-30. Epub 2015 Sep 1.

Orthopaedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1002/jor.22985DOI Listing
February 2016

Lineage tracking of mesenchymal and endothelial progenitors in BMP-induced bone formation.

Bone 2015 Dec 2;81:53-59. Epub 2015 Jul 2.

Centre for Children's Bone Health, The Children's Hospital at Westmead, Westmead, NSW, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2015.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844190PMC
December 2015

Bisphosphonate-adsorbed ceramic nanoparticles increase bone formation in an injectable carrier for bone tissue engineering.

J Tissue Eng 2015 Jan-Dec;6:2041731415609448. Epub 2015 Oct 22.

Orthopaedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Westmead, NSW, Australia ; Discipline of Paediatrics and Child Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1177/2041731415609448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669987PMC
December 2015

PTH(1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in Rats.

J Bone Miner Res 2015 Jun;30(6):1022-9

Orthopaedic Research and Biotechnology Unit, The Children's Hospital at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1002/jbmr.2424DOI Listing
June 2015

Social media: the next frontier in radiology.

Clin Radiol 2015 Jun 26;70(6):585-7. Epub 2015 Mar 26.

Department of Radiology, Southmead Hospital Bristol, Southmead Way, Avon, Bristol BS10 5NB, UK.

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http://dx.doi.org/10.1016/j.crad.2015.02.009DOI Listing
June 2015

The Impact of Aesthetics in Restorative Treatment Planning.

Authors:
David Little

Dent Today 2015 May;34(5):104, 106-7

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May 2015

Animal models of scoliosis.

J Orthop Res 2015 Apr;33(4):458-67

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Sydney, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1002/jor.22797DOI Listing
April 2015

Hip decompression of unstable slipped capital femoral epiphysis: a systematic review and meta-analysis.

J Child Orthop 2015 Apr 17;9(2):113-20. Epub 2015 Mar 17.

Department of Orthopedic Surgery, Hamad General Hospital, Weill Cornell Medical College in Qatar, P.O. Box 3050, Doha, Qatar,

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http://dx.doi.org/10.1007/s11832-015-0648-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417737PMC
April 2015

Paradigm shift: digital processing altering denture fabrication.

Compend Contin Educ Dent 2015 Apr;36(4):242-3

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April 2015

Environmental forensics evaluation of sources of sediment hydrocarbon contamination in Milford Haven Waterway.

Environ Sci Process Impacts 2015 Feb;17(2):398-420

David I. Little (MA PhD) Limited, Environmental Consultancy, Swavesey, Cambridgeshire, Cambridge, CB24 4RL, UK.

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http://dx.doi.org/10.1039/c4em00522hDOI Listing
February 2015

Local delivery of the cationic steroid antibiotic CSA-90 enables osseous union in a rat open fracture model of Staphylococcus aureus infection.

J Bone Joint Surg Am 2015 Feb;97(4):302-9

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia. E-mail address for A. Schindeler: E-mail address for N.Y.C. Yu: E-mail address for T.L. Cheng: E-mail address for K. Sullivan: E-mail address for K. Mikulec: E-mail address for L. Peacock: E-mail address for D.G. Little:

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http://dx.doi.org/10.2106/JBJS.N.00840DOI Listing
February 2015

Inducible cell labeling and lineage tracking during fracture repair.

Dev Growth Differ 2015 Jan 11;57(1):10-23. Epub 2014 Nov 11.

Department of Orthopaedic Research & Biotechnology, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia; MCI Management Center Innsbruck, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1111/dgd.12184DOI Listing
January 2015

Activated protein C (APC) can increase bone anabolism via a protease-activated receptor (PAR)1/2 dependent mechanism.

J Orthop Res 2014 Dec 15;32(12):1549-56. Epub 2014 Sep 15.

Sutton Arthritis Research Laboratory, Kolling Institute at Royal North Shore Hospital, Sydney, Australia.

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http://dx.doi.org/10.1002/jor.22726DOI Listing
December 2014

A regional teaching fellow community of practice.

Clin Teach 2014 Dec;11(7):516-9

Department of Radiology, Bristol Royal Infirmary, Bristol, UK.

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http://dx.doi.org/10.1111/tct.12229DOI Listing
December 2014

Bilateral clubfeet are highly correlated: a cautionary tale for researchers.

Clin Orthop Relat Res 2014 Nov 15;472(11):3517-22. Epub 2014 Jul 15.

Physiotherapy Department, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia,

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http://link.springer.com/content/pdf/10.1007/s11999-014-3776
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http://dx.doi.org/10.1007/s11999-014-3776-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182368PMC
November 2014

Unilateral versus bilateral clubfoot: an analysis of severity and correlation.

J Pediatr Orthop B 2014 Sep;23(5):397-9

aDepartment of Orthopaedic Surgery, The Children's Hospital at Westmead, The Sydney Children's Hospital Network bPaediatric Gait Analysis Service of NSW, The Sydney Children's Hospital Network cNational Health and Medical Research Council Clinical Trials Centre dUniversity of Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1097/BPB.0000000000000064DOI Listing
September 2014

Maximizing bone formation in posterior spine fusion using rhBMP-2 and zoledronic acid in wild type and NF1 deficient mice.

J Orthop Res 2014 Aug 9;32(8):1090-4. Epub 2014 Apr 9.

The Centre for Children's Bone Health, Sydney Children's Hospital Network, Sydney, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1002/jor.22628DOI Listing
August 2014

Interventions for congenital talipes equinovarus (clubfoot).

Cochrane Database Syst Rev 2014 Aug 12(8):CD008602. Epub 2014 Aug 12.

Department of Physiotherapy, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, New South Wales, Australia, 2145.

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http://dx.doi.org/10.1002/14651858.CD008602.pub3DOI Listing
August 2014

Quantitative phenotyping of bone fracture repair: a review.

Bonekey Rep 2014 30;3:550. Epub 2014 Jul 30.

Institute for Biomechanics, Department of Health Sciences and Technology, ETH Zurich , Zurich, Switzerland ; Bioengineering Science Research Group, Faculty of Engineering and the Environment, University of Southampton , Southampton, United Kingdom.

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http://dx.doi.org/10.1038/bonekey.2014.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119206PMC
August 2014

Implant solutions for the implant patient: diagnosis and treatment planning for predictable results.

Authors:
David Little

J Indiana Dent Assoc 2014 ;93(2):26-30

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July 2014

A collagen-hydroxyapatite scaffold allows for binding and co-delivery of recombinant bone morphogenetic proteins and bisphosphonates.

Acta Biomater 2014 May 21;10(5):2250-8. Epub 2014 Jan 21.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Sydney, NSW, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.actbio.2014.01.016DOI Listing
May 2014

Are radiologists the contemporary anatomists?

Clin Radiol 2014 May 11;69(5):458-61. Epub 2014 Mar 11.

Division of Medical and Dental Education, School of Medicine and Dentistry, University of Aberdeen, Lilian Sutton Building, Foresterhill, Aberdeen AB25 2ZD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.crad.2014.01.014DOI Listing
May 2014

Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis.

J Med Chem 2014 May 24;57(9):3755-72. Epub 2014 Apr 24.

Tsinghua-Peking Center for Life Sciences and ‡Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University , Haidian Dist., Beijing 100084, P. R. China.

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http://dx.doi.org/10.1021/jm4019228DOI Listing
May 2014

Benzimidazole-based compounds kill Mycobacterium tuberculosis.

Eur J Med Chem 2014 Mar 31;75:336-53. Epub 2014 Jan 31.

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 2A Nanwei Road, Xuanwu District, Beijing 100050, PR China; Tsinghua-Peking Center for Life Sciences and School of Medicine, Tsinghua University, Haidian Dist., Beijing 100084, PR China; Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University, Haidian Dist., Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.01.039DOI Listing
March 2014

Near-infrared spectroscopy for detection of vascular compromise in paediatric supracondylar fractures.

Physiol Meas 2014 Mar 20;35(3):471-81. Epub 2014 Feb 20.

Department of Anaesthesia, The Children's Hospital at Westmead, Sydney, Australia. Discipline of Paediatrics and Child Health, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1088/0967-3334/35/3/471DOI Listing
March 2014

Is tibialis anterior tendon transfer effective for recurrent clubfoot?

Clin Orthop Relat Res 2014 Feb 24;472(2):750-8. Epub 2013 Sep 24.

Department of Orthopaedic Surgery, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia,

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http://dx.doi.org/10.1007/s11999-013-3287-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890208PMC
February 2014

Implant solutions for the implant patient: diagnosis and treatment planning for predictable results.

Authors:
David Little

Tex Dent J 2014 Feb;131(2):160-3

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February 2014

Neuropeptide Y modulates fracture healing through Y1 receptor signaling.

J Orthop Res 2013 Oct 3;31(10):1570-8. Epub 2013 Jun 3.

Instituto de Engenharia Biomédica (INEB), NEWTherapies Group, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/jor.22400DOI Listing
October 2013

Use of zoledronic acid for treatment of chemotherapy related osteonecrosis in children and adolescents: a retrospective analysis.

Pediatr Blood Cancer 2013 Sep 26;60(9):1539-45. Epub 2013 Apr 26.

Department of Oncology, The Children's Hospital at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1002/pbc.24563DOI Listing
September 2013

Cell-scaffold interactions in the bone tissue engineering triad.

Eur Cell Mater 2013 Sep 20;26:120-32. Epub 2013 Sep 20.

Orthopaedic Research and Biotechnology, Research Building, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145,

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http://dx.doi.org/10.22203/ecm.v026a09DOI Listing
September 2013

Cellular transitions and tissue engineering.

Cell Reprogram 2013 Apr;15(2):101-6

Department of Orthopaedic Research & Biotechnology, the Children's Hospital at Westmead, Sydney, Australia.

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http://dx.doi.org/10.1089/cell.2012.0054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616450PMC
April 2013

Modulation of anabolic and catabolic responses via a porous polymer scaffold manufactured using thermally induced phase separation.

Eur Cell Mater 2013 Feb 27;25:190-203. Epub 2013 Feb 27.

Department of Orthopaedic Research & Biotechnology, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia; School of Aerospace, Mechanical and Mechatronic Engineering, J07 University of Sydney, NSW, 2006, Australia.

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http://dx.doi.org/10.22203/ecm.v025a14DOI Listing
February 2013

Posterolateral inter-transverse lumbar fusion in a mouse model.

J Orthop Surg Res 2013 Jan 23;8. Epub 2013 Jan 23.

Orthopaedic Research & Biotechnology Unit, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW, 2145, Australia.

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http://dx.doi.org/10.1186/1749-799X-8-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564784PMC
January 2013

IVC filter limb penetration of the caval wall during retroperitoneal surgery/lymph node dissection.

J Med Imaging Radiat Oncol 2012 Dec 25;56(6):646-9. Epub 2012 Jun 25.

Departments of Radiology Surgery, Beaumont Hospital, Beaumont, Dublin, Ireland.

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http://dx.doi.org/10.1111/j.1754-9485.2012.02396.xDOI Listing
December 2012

Interplay of Nkx3.2, Sox9 and Pax3 regulates chondrogenic differentiation of muscle progenitor cells.

PLoS One 2012 2;7(7):e39642. Epub 2012 Jul 2.

Program in Cellular, Molecular and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039642PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388093PMC
November 2012

Use of BMPs and bisphosphonates in improving bone fracture healing.

Front Biosci (Elite Ed) 2012 Jun 1;4:2647-53. Epub 2012 Jun 1.

Department of Orthopaedic Research and Biotechnology, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia.

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http://dx.doi.org/10.2741/e572DOI Listing
June 2012