Publications by authors named "David Launay"

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Efficacy and safety of rituximab in systemic sclerosis: French retrospective study and literature review.
Autoimmun Rev 2018 Jun 7;17(6):582-587. Epub 2018 Apr 7.
Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Assistance Publique - Hôpitaux de Paris, Hôpital Saint-Antoine, 184, rue du Faubourg Saint-Antoine, 75012 Paris, France; Sorbonne Universités, UMPC University Paris 06, INSERM U938, Centre de Recherche Saint-Antoine (CRSA), Paris, France. Electronic address:


Altered B lymphocyte homeostasis and functions in systemic sclerosis.
Autoimmun Rev 2018 Mar 16;17(3):244-255. Epub 2018 Jan 16.
Univ. Lille, U995, Lille Inflammation Research International Center (LIRIC), F-59000 Lille, France; Inserm, U995, F-59000 Lille, France; CHU Lille, Institut d'immunologie, F-59000 Lille, France.



No specific imaging pattern can help differentiate IgG4-related disease from idiopathic retroperitoneal fibrosis: 18 histologically proven cases.
Clin Exp Rheumatol 2018 May-Jun;36(3):371-375. Epub 2018 Feb 14.
Dept. of Internal Medicine and Clinical Immunology, CHRU Lille; Centre National de Référence Maladies Systémiques et Auto-Immunes Rares; FHU Immune-Mediated Inflammatory Diseases & Targeted Therapies (IMMINeNT), Lille, France.

Remission of Refractory Systemic-Onset Juvenile Idiopathic Arthritis After Treatment With Siltuximab.
J Clin Rheumatol 2018 Feb 27. Epub 2018 Feb 27.
Department of Internal Medicine and Clinical Immunology Referral Centre for Rare Systemic Auto-immune Diseases for North and North-West of France (CeRAINO), University of Lille Huriez Hospital Lille, Department of Pediatric Immunology Paris-Descartes, Imagine Institute Pediatric Immunology Hematology and Rheumatology Unit, Hôpital Necker-Enfants Malades Assistance Publique-Hôpitaux de Paris Paris, France. Department of Internal Medicine and Clinical Immunology, Referral Centre for Rare Systemic Auto-immune Diseases for North and North-West of France (CeRAINO), University of Lille Huriez Hospital Lille, France.

Self-efficacy for deprescribing: A survey for health care professionals using evidence-based deprescribing guidelines.
Res Social Adm Pharm 2018 Jan 28;14(1):18-25. Epub 2017 Jan 28.
Bruyère Research Institute, 43 Bruyère Street, Ottawa, Ontario K1N 5C8, Canada; Department of Applied Human Sciences, Concordia University, 1455 de Maisonneuve Blvd. West, Montreal, Quebec H3G 1M8, Canada. Electronic address:

Pulmonary Arterial Hypertension Associated With Systemic Lupus Erythematosus: Results From the French Pulmonary Hypertension Registry.
Chest 2018 Jan 26;153(1):143-151. Epub 2017 Aug 26.
Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre; AP-HP, Centre de reference de l'Hypertension Pulmonaire, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre; INSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson, France.

Limited Exercise Capacity in Patients with Systemic Sclerosis: Identifying Contributing Factors with Cardiopulmonary Exercise Testing.
J Rheumatol 2018 Jan 1;45(1):95-102. Epub 2017 Nov 1.
From the Service de Médecine Interne, Centre Hospitalier Universitaire (CHU) de Nice, Nice; University of Lille, U995 Lille Inflammation Research International Center (LIRIC), Lille; INSERM, U995, Lille; CHU Lille, Département de Médecine Interne et Immunologie Clinique, Lille; Centre national de référence maladies systémiques et auto-immunes rares (sclérodermie systémique), Lille; Service d'Explorations Fonctionnelles Respiratoires, CHU de Lille, Lille; FHU OncoAge, Côte d'Azur University, Nice, France.


Diagnosis and treatment of upper airway oedema caused by acute angio-oedema in the emergency department: a French consensus statement.
Eur J Emerg Med 2017 Oct;24(5):318-325
aDepartment of Anaesthesiology and Intensive care, Edouard Herriot University Hospital bDepartment of Clinical Research and Innovation, Hospices Civils de Lyon, Lyon cEmergency Department, Louis Mourier University Hospital, Paris 7 University dDepartment of Internal Medicine, Saint Antoine University Hospital, Paris 6 University, Assistance Publique-Hôpitaux de Paris, Paris eDepartment of Internal Medicine, Grenoble University Hospital, Grenoble-Alpes University, Grenoble fDepartment of Dermatology, Gabriel-Montpied University Hospital, Clermont-Ferrand gDepartment of Internal Medicine, Niort Hospital, Niort hDepartment of Internal Medicine, Archet 1 University Hospital, Nice Sophia-Antipolis University, Nice iDepartment of Medicine, Saint Louis University Hospital, Saint Pierre, Réunion jDepartment of Internal Medicine, Caen University Hospital, Caen kDepartment of Dermatology and Allergology, Grenoble University Hospital, Grenoble lDepartment of Internal Medicine, Timone University Hospital, Assistance Publique-Hôpitaux de Marseille, Marseille mDepartment of Dermatology, Saint Eloi University Hospital, Montpellier nDepartment of Dermatology, Besançon University Hospital, Franche-Comté University, INSERM UMR 1098, Besançon oDepartment of Internal Medicine Toulouse University Hospital, Toulouse University, Toulouse pDepartment of Internal Medicine, Lille University Hospital, Lille University, INSERM U995 Lille, Lille, France.



Central nervous system involvement in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Report of 26 patients and review of the literature.
Autoimmun Rev 2017 Sep 12;16(9):963-969. Epub 2017 Jul 12.
Department of Internal Medicine, Hôpital Cochin, F-75014 Paris, France; National Referral Center for Systemic and Autoimmune Diseases, Hôpital Cochin, F-75014 Paris, France; Université Paris Descartes, Faculté de Médecine Paris Descartes, F-75014 Paris, France; Université Paris Descartes, Paris 5, Paris, France; Inserm, U1016, Institut Cochin, F-75014 Paris, France. Electronic address:


Intravenous immunoglobulins in systemic sclerosis: Data from a French nationwide cohort of 46 patients and review of the literature.
Autoimmun Rev 2017 Apr 13;16(4):377-384. Epub 2017 Feb 13.
Univ. Lille, INSERM U995 - LIRIC - Lille Inflammation Research International Center, F-59000 Lille, France; INSERM, U995, F-59000 Lille, France; CHU Lille, Département de Médecine Interne et Immunologie Clinique, F-59000 Lille, France; Centre National de Référence Maladies Systémiques et Auto-immunes Rares (Sclérodermie Systémique), F-59000 Lille, France; Health Care Provider of the European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ReCONNET). Electronic address:

Hereditary angioedema with normal C1 inhibitor: clinical characteristics and treatment response with plasma-derived human C1 inhibitor concentrate (Berinert) in a French cohort.
Eur J Dermatol 2017 Apr;27(2):155-159
National Reference Centre for Angioedema, CREAK, France, Department of Internal Medicine, Saint Antoine University Hospital, AP-HP, Paris, France.


N-terminal pro-brain natriuretic peptide is a strong predictor of mortality in systemic sclerosis.
Int J Cardiol 2016 Nov 13;223:385-389. Epub 2016 Aug 13.
Department of Cardiology, Paris 13 University, Avicenne Hospital, Bobigny, France; UMR S-942, Paris, France. Electronic address:

Pulmonary arterial hypertension in idiopathic inflammatory myopathies: Data from the French pulmonary hypertension registry and review of the literature.
Medicine (Baltimore) 2016 Sep;95(39):e4911
aUniversity of Lille, INSERM U995, LIRIC, Lille Inflammation Research International Center bCHU Lille, Département de Médecine Interne et Immunologie Clinique cCentre National de Référence Maladies Systémiques et Auto-immunes Rares (Sclérodermie Systémique), Lille dUniversity Paris-Sud, Faculté de Médecine, Université Paris-Saclay eAP-HP, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, Le Kremlin-Bicêtre fINSERM UMR_S999, LabEx LERMIT, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson gDépartement de Médecine Interne et Immunologie Clinique, Centre National de Référence Maladies Neuromusculaires, Hôpital La Pitié-Salpêtrière, AP-HP, INSERM U974, Université Paris VI Pierre et Marie Curie, Paris hClinique Universitaire de Pneumologie, Centre Hospitalier Universitaire, Grenoble, France iUniversité Joseph Fourier, Grenoble jService de médecine interne et rhumatologie 3C/5D, Centre Hospitalier Universitaire Pierre Zobda-Quitman kDépartement de Cardiologie, Centre Hospitalier Universitaire Pierre Zobda-Quitman, Fort-de-France, Martinique lHospices Civils de Lyon, Service de Pneumologie, Centre de Compétence de l'Hypertension Pulmonaire, Centre de Référence des Maladies Pulmonaires Rares, Lyon mService de Médecine Interne, Centre de Référence des Vascularites Nécrosantes et de la Sclérodermie Systémique, Université Paris Descartes, Hôpital Cochin, Paris, France.


A nationwide study of acquired C1-inhibitor deficiency in France: Characteristics and treatment responses in 92 patients.
Medicine (Baltimore) 2016 Aug;95(33):e4363
aInternal Medicine Department, Saint Antoine Hospital, Assistance Publique-Hôpitaux de Paris, DHU i2B, Paris 6 University, Paris bHematology Department, Pitié Salpétrière Hospital, Assistance Publique-Hôpitaux de Paris, Paris 6 University, Paris cImmunology Laboratory, University Hospital, Grenoble dCentre de Référence et d'Etude des Angioedèmes à Kinine (CREAK) , Grenoble ePublic Health Department, Tenon Hospital, Assistance Publique-Hôpitaux de Paris, Paris 6 University fImmunology Laboratory, Georges Pompidou European Hospital, Assistance Publique-Hôpitaux de Paris, Paris 5 University, Paris gJoint Unit 1036 CNRS-CEA-INSERM, University Grenoble Alpes hInternal Medicine Department, University Hospital, Grenoble iUniversité Joseph Fourier Grenoble, GREPI/AGIM CNRS FRE 3405, Grenoble jInternal Medicine Department, La Conception Hospital, AP-HM, Marseille kInternal Medicine and Clinical Immunology Department, Lille University Hospital lLIRIC, INSERM UMR 995, EA2686, Lille mDermatology Department, L'UNAM Université, University Hospital, Angers, France.

Digestive-tract sarcoidosis: French nationwide case-control study of 25 cases.
Medicine (Baltimore) 2016 Jul;95(29):e4279
aAP-HP, Hôpital Saint-Antoine, Sorbonne Universités, UPMC Université Paris 06, service de médecine interne and Inflammation-Immunopathology-Biotherapy Department (DHU i2B) bAPHP, Hôpital Pitié-Salpétrière, Sorbonne Universités, UPMC Université Paris 06, service de médecine interne cAPHP, Hôpital Tenon, Sorbonne Universités, UPMC Université Paris 06, Public health department dAPHP, Hôpital Saint-Antoine, Sorbonne Universités, UPMC Université Paris 06, service de gastro-entérologie, Paris eHôpital de la Croix-Rousse, Hospices Civils de Lyon, department of internal medicine, F-Lyon. University Claude Bernard Lyon 1, F-69100, Villeurbanne. fHôpital Claude Huriez, service de médecine interne, Lille, France gAPHP, Hôpital Avicenne, service de médecine interne, université Paris 13, Bobigny, France hDepartment of internal medicine, Division of internal medicine and rehabilitation, rehabilitation and geriatrics, Geneva University Hospitals and University of Geneva, Geneva, Switzerland iAPHP, Hôpital Avicenne, Université Paris 13, service de pneumologie, Bobigny jHôpital Evreux, service de pneumologie, Evreux kAPHP, Hôpital Avicenne, Université Paris 13, service de médecine nucléaire lAPHP, Hôpital Avicenne, Université Paris 13, service de gastro-entérologie, Bobigny, France .

Efficacy of Anti-TNFα in Severe and Refractory Neuro-Behcet Disease: An Observational Study.
Medicine (Baltimore) 2016 Jun;95(23):e3550
From APHP Groupe Hospitalier Pitié-Salpétrière Paris, France: Service de Medecine Interne et Immunologie Clinique (ACD, PC, DS), Service de Neurologie (RD), and Service de Medecine Interne 2 (FC) Service de Neuroradiologie Diagnostique et Fonctionnelle (AB); DHU Inflammation Immunopathologie, Biothérapie, Université Pierre et Marie Curie, Paris, France (ACD, PC, DS); Inserm U1127, CNRS UMR 7225, Sorbonne Universités, Université Pierre et Marie Curie Paris 6 and UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, Inria Paris-Rocquencourt, F-75013, Paris, France (AB); Service de Médecine Interne, CHU Grenoble, France (AD); Service de Médecine Interne, Groupement Hospitalier-Hôpital Edouard Herriot, Lyon, France (LP); Service de Médecine Interne, Hôpital Claude Huriez, CHRU Lille, France (EH, ML, DL) ; Service de Médecine Interne Hôpital Foch, Suresnes, France (BS, FA); Service de Rhumatologie, CHU Le Kremlin Bicêtre, France (XM) ;Service de Médecine Interne, CHU Bois-Guillaume, Rouen, France (IM); and Rheumatology Unit, Department of Internal Medicine, Reggio Emilia, Italy (OA, CS).

Mastocytosis among elderly patients: A multicenter retrospective French study on 53 patients.
Medicine (Baltimore) 2016 Jun;95(24):e3901
aService de médecine interne, Hôpital Tenon, Université Pierre et Marie Curie, Paris, France bService de Médecine Interne, CHU de Caen, Université Basse Normandie, Caen, France cInstitut d'Hématologie de Basse Normandie, Centre Hospitalier Universitaire, Université de Caen-Basse Normandie, Caen, France dFaculté de Médecine et AP-HP Necker-Enfants Malades, Centre de Référence des Mastocytoses, Paris Cedex 15, France eInserm, U1068, CRCM [Signaling, Hematopoiesis and Mechanism of Oncogenesis], Institut Paoli-Calmettes,Marseille, Aix-Marseille Univ, CNRS, UMR7258, Marseille, France fMastocytosis Competence Center of Midi-Pyrénées, Department of Dermatology, Toulouse University Hospital, Toulouse, France gService de Médecine Interne, Université Claude Bernard Lyon1, Groupe Hospitalier Lyon-Sud. Chemin du Grand Revoyet, Pierre Bénite, France hService de Dermatologie, Hôpital Tenon, Université Pierre et Marie Curie-Paris 6, Paris, France iService d'Hématologie Adultes, Université Paris Descartes, Paris Sorbonne Cité, Faculté de Médecine et AP-HP Necker-Enfants Malades, Institut Imagine, Université Paris Descartes, Paris Cedex 15, France jService de Médecine interne, Hôpital St Antoine, Université Pierre et Marie Curie-Paris 6, Paris, France kService de Médecine interne, Université de Rennes 1, Hôpital Sud CHU Rennes, Rennes, France lService de Médecine interne, Hôpital Pitié Salpêtrière, Université Pierre et Marie Curie-Paris 6, Paris, France mService de Médecine interne, CHU, Nantes, France nService de Médecine interne, Hôpital Européen Georges Pompidou, Université Paris 5, Paris, France oUniversité de Lille, UFR Médecine, Lille, France; CHRU Lille, Pôle Spécialités Médicales et Gérontologie, Département de Médecine Interne et Immunologie Clinique, Lille Cedex, France; Centre National de Référence Maladies Systémiques et Auto-immunes Rares (Sclérodermie Systémique), Lille Cedex, France; LIRIC UMR 995, EA2686, France





Neutrophilic Dermatoses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A French Multicenter Study of 17 Cases and Literature Review.
Medicine (Baltimore) 2016 Mar;95(11):e2957
From the Department of Internal Medicine, Caen University Hospital, Caen (HDB, NMS, BB, AA); Department of Internal Medicine, Brest University Hospital (CDM); Department of Internal Medicine, Nantes University Hospital (AN); Department of Internal Medicine, Assistance Publique Hôpitaux de Paris, Saint-Louis Hospital, Paris, France (MDM); Department of Rheumatology, Assistance Publique Hôpitaux de Paris, Bichat University Hospital, Paris, France (OM); Department of Internal Medicine, Lille University Hospital, France (DL); Mount Sinai Hospital, University Health Network, and University of Toronto, Toronto, Ontario, Canada (CP); and Department of Internal Medicine, Assistancec Publique Hôpitaux de Paris, Cochin Hospital, Paris, France (LG, XP).


A French National Survey on Clotting Disorders in Mastocytosis.
Medicine (Baltimore) 2015 Oct;94(40):e1414
From the French Reference Centre for Mastocytosis (CEREMAST), Necker Children's Hospital, Assistance Publique - Hôpitaux de Paris (APHP), France (ABC, GD, DC, CB, SB, LF, OL, OH, M-OC); Haemostasis and Thrombosis Unit, Haemophilia Clinic, Division of Haematology, St-Luc University Hospital, Brussels, Belgium (ABC, CH); Department of Internal Medicine, Caen University Hospital, France (AA); Department of Haematology, Caen University Hospital, France (GD); Department of Pathology, Necker Children's Hospital, APHP, France (DC); Department of Biological Haematology, Necker Children's Hospital, APHP, France (CB); Department of Haematology and Cell Therapy, Tours University Hospital, France (EG); Department of Internal and Vascular Medicine, Lyon Sud University Hospital, France (SD, ID); Department of Internal Medicine, Saint-Etienne University Hospital, France (PC); Department of Internal Medicine, Cochin Hospital, APHP, France (NC-C); Department of Internal Medicine, Lille University Hospital, France (DL); Infectious Diseases Department, Necker Children's Hospital, APHP, France (BP, OL); Department of Dermatology, Tenon University Hospital, APHP, France (SB); Department of Haematology, Necker Children's Hospital, APHP, France (LF, OH, M-OC); and Sorbonne Paris Cité, Paris Descartes University, Imagine Institute, Paris, France (LF, OL, OH, M-OC).


Distinctive Patterns of Transthyretin Amyloid in Salivary Tissue: A Clinicopathologic Study of 92 Patients With Amyloid-containing Minor Salivary Gland Biopsies.
Am J Surg Pathol 2015 Aug;39(8):1035-44
Departments of *Pathology †Internal Medicine ‡Biochemistry and Molecular Biology, UF Génopathies §Nephrology ∥Neurology ¶Cardiology #Hematology, CHRU de Lille, Regional Competence Center for Systemic Amyloidosis, and University Lille Nord de France, F-59000, Lille **Laboratoire de Génétique Moléculaire, Pharmacogénétique et Hormonologie, Assistance Publique - Hôpitaux de Paris, Hôpital Bicêtre, CHU Paris Sud, Université Paris Sud, Le Kremlin Bicêtre ††Laboratoire de Biochimie et Génétique Moléculaire, Faculté de Médecine Paris, Université Paris Descartes, Sorbonne Paris Cité, Assistance Publique - Hôpitaux de Paris, Groupe Hospitalier Cochin-Hôtel Dieu; INSERM, Centre de Recherche des Cordeliers, URMS 872, équipe 17 ‡‡Pathology Department, Hôpital Tenon, Assistance Publique - Hôpitaux de Paris, Sorbonne Universités, UPMC Paris 6, Paris, France, F-75020.

Value of systolic pulmonary arterial pressure as a prognostic factor of death in the systemic sclerosis EUSTAR population.
Rheumatology (Oxford) 2015 Jul 17;54(7):1262-9. Epub 2015 Jan 17.
National Scleroderma Reference Centre, Department of Internal Medicine, Lille Nord University, Lille, Orgamétrie biostatistiques, Roubaix, France, UO Reumatologia e Immunologia Clinica, Spedali Civili Brescia, Dipartimento Medicina Clinica e Sperimentale F-Magrassi II Policlinico U.O., Reumatologia, Napoli, Italy, Rheumatology A dpt, Paris 5 University, Cochin Hospital, Paris, France, Rheumatology Unit, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Centro per la Sclerosi Sistemica - Dipartimento di Medicina Clinica, Università La Sapienza, Policlinico Umberto I, Roma, Italy, Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, Divisione di Reumatologia, Università di Roma La Sapienza, Dipartimento di Clinica e Terapia medica applicata, Policlinico Umberto I, Roma, Ospedale Mauriziano, Centro di Reumatologia, Torino, Italy, Centre for Rheumatology, Royal Free and University College London Medical School, Royal Free Campus, London, UK, Department of Rheumatology, Charité University Hospital, German Rheumatism Research Centre, a Leibniz institute, Berlin, Germany, Dipartimento di Medicina, Ospedale San Gerardo, Monza, Dipartimento e Cattedra di Reumatologia, Università degli Studi di Milano, Istituto Ortopedico Gaetano Pini, Milano, Italy, Department of Internal Medicine and Rheumatology Clinic, Ion Cantacuzino Clinical Hospital, Bucharest, Romania, University Hospital of Copenhagen, Department of Dermatology D-40, HS-Bispebjerg Hospital, Copenhagen, Denmark, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, Clinica Reumatologie, University of Medicine & Pharmacy, Iuliu Hatieganu Cluj, Cluj-Napoca, Romania, Ghent University Hospital, Department of Rheumatology, Gent, Belgium, Rheumatologische Universitätsklinik, Felix Platter Spital, Basel, Switzerland, University of Florence, Department of Medicine, Section of Rheumatology, Florence, Italy and Lehrstuhl für Innere Medizin mit Schwerpunkt Rheumatologie der

Factors associated with hospital admission in hereditary angioedema attacks: a multicenter prospective study.
Ann Allergy Asthma Immunol 2015 Jun 29;114(6):499-503. Epub 2015 Apr 29.
Service de Médecine Interne, Centre de Référence associé sur les angioedèmes à kinines (CRéAk), Assistance Publique-Hôpitaux de Paris, Hôpital Jean Verdier, Université Paris 13, Bondy, France.

Seronegative polyarthritis revealing antisynthetase syndrome: a multicentre study of 40 patients.
Rheumatology (Oxford) 2015 May 27;54(5):927-32. Epub 2014 Oct 27.
Service de Médecine Interne, Unité d'Immunologie Clinique, Centre de Référence pour les Maladies Auto-Immunes et Systémiques Rares, Hôpital Claude Huriez, CHRU de Lille, Université Lille Nord de France, Laboratoire d'Immunologie, EA 2686, IMPRT IFR 114, CHRU de Lille, Faculté de Médecine H. Warembourg, Université Lille Nord de France, Lille, Service de Rhumatologie, Centre de Référence Maladies Systémiques Rares, CHU Hautepierre, Strasbourg, Service de Rhumatologie, Hôpital Pellegrin, CHU de Bordeaux, Bordeaux, Service de Rhumatologie, CHU Fort-De-France, La Meynard, Fort-De-France, Service de Rhumatologie, CHU de Rouen, Hôpitaux de Rouen, Rouen, Service de Rhumatologie, CHU Clermont-Ferrand, Clermont-Ferrand, Service de Médecine Interne, Maladies Infectieuses et Tropicales, Hématologie, CH Bretagne Atlantique, Vannes-Auray, Vannes, Service de Médecine Interne, Hôpital Foch, AP-HP, Suresnes, Service de Rhumatologie, CHU de Limoges, Limoges, Service de Rhumatologie, CHU de la Cavale-Blanche, Brest, Service de Médecine Interne, Hôpital de la Conception, Assistance publique-Hôpitaux de Marseille, Aix-Marseille Université, Marseille, Service de Rhumatologie, CHRU Jean Minjoz, Besançon, Service de Médecine, Pôle A, Rhumatologie, CH de Nevers, Nevers, Rhumatologue, Château-Thierry, France, Service de Rhumatologie - Médecine Interne, CHU Brugmann, Brussels, Belgium, Service de Pneumologie et Immuno-Allergologie, Centre de Compétence des Maladies Pulmonaires Rares, Hôpital Calmette, CHRU de Lille, Université de Lille Nord de France, Lille, Service de Médecine Interne 1, DHU-I2B, Centre de Référence des Maladies Neuromusculaires Paris-Est, Hôpital de la Pitié-Salpêtrière, AP-HP, Université Paris 6 Pierre et Marie Curie, Paris, Service de Rhumatologie, Hôpital Roger Salengro, CHU de Lille, Université Lille Nord de France and Service de Médecine Interne 2, Centre de Référence Lupus et SAPL, Hôpital de la Pitié-Salpêtrière, AP-HP,

[Hereditary angiœdema treatments: Recommendations from the French national center for angiœdema (Bordeaux consensus 2014)].
Presse Med 2015 May 29;44(5):526-32. Epub 2015 Apr 29.
CHU de Grenoble, centre national de référence des angiœdèmes, 38043 Grenoble cedex 09, France; Université Paris 6, AP-HP, hôpital Saint-Antoine, service de médecine interne, 75012 Paris, France.

[Angioedema: differential diagnosis].
Presse Med 2015 Jan 18;44(1):30-6. Epub 2014 Dec 18.
Université de Lille, faculté de médecine, 59045 Lille cedex, France; CHRU de Lille, hôpital Claude-Huriez, Centre national de référence de la sclérodermie systémique, service de médecine interne, 59037 Lille cedex, France; EA2686, 59000 Lille, France; Centre national de référence des angiœdèmes à kinine (CREAK), 38700 La Tronche, France. Electronic address:

Systemic sclerosis and prevalence of monoclonal immunoglobulin.
Autoimmun Rev 2014 Dec 23;13(12):1189-94. Epub 2014 Aug 23.
Université Pierre et Marie Curie, Paris 6, 75013 Paris, France; AP-HP, Service de Dermatologie-Allergologie, Hôpital Tenon, 75020 Paris, France.

Lung and heart-lung transplantation for systemic sclerosis patients. A monocentric experience of 13 patients, review of the literature and position paper of a multidisciplinary Working Group.
Presse Med 2014 Oct 11;43(10 Pt 2):e345-63. Epub 2014 Jul 11.
Université Paris-Sud, faculté de médecine, 94270 Le Kremlin-Bicêtre, France; Inserm U999, Centre chirurgical Marie-Lannelongue, LabEx LERMIT, 92350 Le Plessis-Robinson, France; Centre chirurgical Marie-Lannelongue, service de chirurgie thoracique, vasculaire et de transplantation cardiopulmonaire, 92350 Le Plessis-Robinson, France. Electronic address:


The lymphoid variant of hypereosinophilic syndrome: study of 21 patients with CD3-CD4+ aberrant T-cell phenotype.
Medicine (Baltimore) 2014 Oct;93(17):255-66
Institut d'Immunologie, Réseau Eosinophile, EA2686 (GL, FL, DL, ML, JT, JEK), Service d'Immunologie Clinique et de Médecine Interne, Centre de Référence Maladies Auto-Immunes Systémiques (GL, DL, LT, NLG, PYH), Institut de Pathologie (MCC), Service de Dermatologie (DSS), Service des Maladies du Sang (FM), Institut de Génétique Médicale, U837 Inserm (CRL), Réseau Eosinophile, U995 Inserm (MC), CHRU de Lille, Université Lille Nord de France, Lille; Service de Dermatologie (MAA, CL), CHU d'Angers, L'UNAM Université, Angers; Service de Dermatologie et Dermatologie Pédiatrique, Centre de Référence pour les Maladies Rares de la Peau, U1035 (AT), CHU de Bordeaux, Bordeaux; Service d'Hématologie (GS) and Service de Radiologie, CREATIS, UMR5220 CNRS, U1044 Inserm (FC), Hôpital Sud, Service de Pneumologie, Centre de Référence pour les Maladies Pulmonaires Rares (CK), Hospices Civils de Lyon, Université Claude Bernard Lyon I, Lyon; Service d'Onco-Hématologie (HM), Centre Hospitalier de La Roche-Sur-Yon, La Roche-Sur-Yon; Service d'Onco-Hématologie (KG), Centre Hospitalier de Beauvais, Beauvais; Service de Médecine Interne (FA), Hôpital Bicêtre, APHP, Université Paris Sud XI, Le Kremlin-Bicêtre; Service d'Hématologie et Immunologie Pédiatrique (AB), Hôpital Robert Debré, APHP, Université Paris Diderot and Service de Pneumologie A, Centre de Compétence Maladies Pulmonaires Rares (RB), Hôpital Bichat, APHP, Paris; Service de Médecine Interne (CMH), Centre Hospitalier d'Annecy, Annecy; Service de Médecine Interne, Hôpital Foch, Suresne; EA4340, Biomarqueurs en Cancérologie et en Onco-Hématologie, Université Versailles-Saint-Quentin-en-Yvelines (JEK), France.

Serum free light chains of immunoglobulins as biomarkers for systemic sclerosis characteristics, activity and severity.
Autoimmun Rev 2014 Sep 25;13(9):974-80. Epub 2014 Jul 25.
Université Lille Nord de France, Lille, France; EA2686, IMPRT IFR 114, Faculté de Médecine, Lille, France; Institut d'Immunologie, Centre de Biologie-Pathologie-Génétique, CHRU Lille, Lille, France.

Predictors of early relapse in patients with non-infectious mixed cryoglobulinemia vasculitis: results from the French nationwide CryoVas survey.
Autoimmun Rev 2014 Jun 10;13(6):630-4. Epub 2014 Jan 10.
Department of Internal Medicine, Reference Center for Autoimmune Diseases, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Université Pierre et Marie Curie, Paris 6, UMR 7211, F-75005 Paris, France; INSERM, UMR S 959, F-75013 Paris, France; CNRS, UMR 7211, F-75005 Paris, France; Departement Hospitalo-Universitaire I2B, Univ Paris 06, UMR 7211, F-75005, Paris, France; AP-HP, Groupe Hoitalier Pitié-Salpérière, Departement of Internal Médicine, 75013, Paris, France. Electronic address:

Risk factors for severe bacterial infections in patients with systemic autoimmune diseases receiving rituximab.
Clin Rheumatol 2014 Jun 2;33(6):799-805. Epub 2014 Feb 2.
National Reference Centre for Systemic Autoimmune Diseases, Department of Internal Medicine, Claude Huriez Hospital, Université de Lille Nord-de-France, Lille, France.


Immunological profiles determine neurological involvement in Sjögren's syndrome.
Eur J Intern Med 2014 Feb 29;25(2):177-81. Epub 2013 Oct 29.
Department of Internal Medicine, Limoges University Hospital, Limoges F-87042, France; EA 3842 - Department of Immunology, Limoges University, Limoges F-87042, France.

Prevalence of anti-RNA polymerase III antibodies in systemic sclerosis: New data from a French cohort and a systematic review and meta-analysis.
Arthritis Rheumatol 2014 Feb;66(2):407-17
Université Lille Nord de France, EA 2686, IMPRT IFR 114, Centre National de Référence de la Sclérodermie Systémique, and Hôpital Claude Huriez, Centre Hospitalier Régional Universitaire de Lille, Lille, France.

Inflammatory arthritis in patients with myelodysplastic syndromes: a multicenter retrospective study and literature review of 68 cases.
Medicine (Baltimore) 2014 Jan;93(1):1-10
From the Service de médecine interne (AM, EG, OF), Université Paris 13, AP-HP, Hôpital Jean Verdier, Bondy; Service d'hématologie clinique (TB, PF), Université Paris 13, AP-HP, Avicenne, Bobigny; Service de médecine interne (OD), Université Rennes 1, Hôpital Universitaire de Rennes, Rennes; Service de rhumatologie (GF), Université Sorbonne Paris Cité, Université Paris 13, Li2P, EA4222, Hôpital Avicenne, Bobigny; Centre Investigation Clinique Biothérapie CBT-506 & Service de rhumatologie (ET), CHU Besançon, Besançon; Service de médecine interne (LR), CHU de Bordeaux, Bordeaux; Service de rhumatologie (MO), CH Romilly/Seine; Service de médecine interne (BG), Hôpital de La Rochelle, La Rochelle; Service de médecine interne et gériatrique (BDW), CHU Nîmes, Nîmes; Service de médecine interne (A-LB), CH Douai, Douai; Service de rhumatologie (J-MZ), CH Croix Saint Simon, Paris; Service de médecine interne (DL), CHU Lille, Université Lille II, Lille; Service de médecine interne (GD), Hôpital de Rochefort, Rochefort; Service de médecine interne (SM), CHG Albi, Albi; and Service d'hématologie clinique (CR), Hôpital Saint-Vincent de Paul, UC Lille, Univ Nord de France, Lille; France.

Survival in systemic sclerosis-associated pulmonary arterial hypertension in the modern management era.
Ann Rheum Dis 2013 Dec 24;72(12):1940-6. Epub 2012 Nov 24.
Service de Médecine Interne, Centre de référence de la sclérodermie systémique, Université Lille Nord de France, Hôpital Claude-Huriez, , Lille, France.


Pulmonary hypertension in antisynthetase syndrome: prevalence, aetiology and survival.
Eur Respir J 2013 Nov 8;42(5):1271-82. Epub 2013 Feb 8.
French Reference Center for Lupus, Hôpital Pitié-Salpêtrière, APHP, University of Paris VI Pierre and Marie Curie, Paris.

Hereditary angioedema with C1 inhibitor deficiency: clinical presentation and quality of life of 193 French patients.
Ann Allergy Asthma Immunol 2013 Oct 6;111(4):290-4. Epub 2013 Aug 6.
Department of Internal Medicine, University Hospital, Grenoble, France. Electronic address:










Comparison of the Farr radioimmunoassay, 3 commercial enzyme immunoassays and Crithidia luciliae immunofluorescence test for diagnosis and activity assessment of systemic lupus erythematosus.
Clin Chim Acta 2010 Jul 19;411(13-14):959-64. Epub 2010 Mar 19.
Service de Médecine Interne, Centre National de Référence des Maladies Autoimmunes et Systémiques Rares (Sclérodermie), Centre Hospitalier Régional et Universitaire, Université Lille 2, Lille, France.


[Screening and diagnosis of pulmonary arterial hypertension. Comments regarding the latest guidelines from the European Societies of Cardiology and of Pulmonology].
Presse Med 2010 Jun;39 Suppl 1:1S16-21
CHRU, Hôpital Cardiologique, Service de Cardiologie C, Pôle de Cardiologie et Maladies Vasculaires, 59037 Lille cedex, Centre de Compétences HTAP. Université de Lille 2, France.

Pulmonary arterial hypertension associated with systemic sclerosis in patients with functional class II dyspnoea: mild symptoms but severe outcome.
Rheumatology (Oxford) 2010 May 8;49(5):940-4. Epub 2010 Feb 8.
Department of Internal Medicine, National Reference Center for Scleroderma, Claude Huriez Hospital, University of Lille, France.

Effect of in vitro and in vivo anakinra on cytokines production in Schnitzler syndrome.
PLoS One 2013 19;8(3):e59327. Epub 2013 Mar 19.
Lille Nord de France University, Department of Internal Medicine and Clinical Immunology, National Reference Center for Rare Autoimmune and Systemic Diseases, Lille, France.

Relevance of partitioning DLCO to detect pulmonary hypertension in systemic sclerosis.
PLoS One 2013 18;8(10):e78001. Epub 2013 Oct 18.
Service de Médecine Interne, Centre de Référence des Maladies Autoimmunes et Systémiques Rares (Sclérodermie), Centre de Compétence de l'Hypertension Artérielle Pulmonaire Sévère, Université Lille Nord de France, Hôpital Claude-Huriez, CHRU Lille, Lille, France.

ASXL1 but not TET2 mutations adversely impact overall survival of patients suffering systemic mastocytosis with associated clonal hematologic non-mast-cell diseases.
PLoS One 2014 21;9(1):e85362. Epub 2014 Jan 21.
Centre de Référence des Mastocytoses, Faculté de Médecine et AP-HP Necker-Enfants Malades, Paris, France ; CNRS UMR 8147 and Institut Imagine, AP-HP, Hôpital Necker-Enfants Malades, Paris, France ; Service d'Hématologie Adulte, Université Paris Descartes, Paris Sorbonne Cité, Faculté de Médecine et AP-HP Necker-Enfants Malades, Paris, France.

B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis.
Front Immunol 2017 7;8:53. Epub 2017 Feb 7.
U995, LIRIC - Lille Inflammation Research International Center, Université de Lille, Lille, France; INSERM, U995, Lille, France; Département de Médecine Interne et Immunologie Clinique, CHU Lille, Lille, France; Centre National de Référence Maladies Systémiques et Auto-immunes Rares (Sclérodermie Systémique), Lille, France.


Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis.
Arthritis Rheumatol 2017 11 17;69(11):2209-2221. Epub 2017 Oct 17.
Université Paris Descartes, Sorbonne Paris Cité, INSERM U1016 and CNRS UMR8104, Institut Cochin, and Université Paris Descartes, Sorbonne Paris Cité, Service de Rhumatologie A, Hôpital Cochin, Paris, France.



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