Publications by authors named "David L Silver"

47Publications

Mfsd2a: A Physiologically Important Lysolipid Transporter in the Brain and Eye.

Adv Exp Med Biol 2020 ;1276:223-234

Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore.

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December 2020

The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.

PLoS Biol 2018 08 3;16(8):e2006443. Epub 2018 Aug 3.

Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore, Singapore.

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August 2018

Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A.

J Biol Chem 2016 Apr 4;291(18):9383-94. Epub 2016 Mar 4.

From the Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Graduate Medical School, Singapore 169857,

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April 2016

Postnatal Deletion of Fat Storage-inducing Transmembrane Protein 2 (FIT2/FITM2) Causes Lethal Enteropathy.

J Biol Chem 2015 Oct 24;290(42):25686-99. Epub 2015 Aug 24.

From the Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Graduate Medical School, 8 College Road, 169857 Singapore and

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October 2015

A novel splice-site mutation in ALS2 establishes the diagnosis of juvenile amyotrophic lateral sclerosis in a family with early onset anarthria and generalized dystonias.

PLoS One 2014 4;9(12):e113258. Epub 2014 Dec 4.

Human Genetics, Genome Institute of Singapore, A*STAR, Singapore, Singapore; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

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August 2015

CCAAT/enhancer binding protein α predicts poorer prognosis and prevents energy starvation-induced cell death in hepatocellular carcinoma.

Hepatology 2015 Mar 30;61(3):965-78. Epub 2015 Jan 30.

Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; School of Public Health, Guangxi Medical University, China.

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March 2015

Cytosolic lipid droplets: from mechanisms of fat storage to disease.

Crit Rev Biochem Mol Biol 2014 Jul-Aug;49(4):304-26

Program in Cardiovascular & Metabolic Disorders, Duke-NUS Graduate Medical School Singapore , Singapore , and.

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February 2015

MicroRNAs are required for the feature maintenance and differentiation of brown adipocytes.

Diabetes 2014 Dec 9;63(12):4045-56. Epub 2014 Jul 9.

Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Graduate Medical School, Singapore Institute of Molecular and Cell Biology, Singapore

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December 2014

Recent advances in understanding proteins involved in lipid droplet formation, growth and fusion.

J Genet Genomics 2014 May 19;41(5):251-9. Epub 2014 Mar 19.

Signature Research Program in Cardiovascular & Metabolic Disorders, Duke-NUS Graduate Medical School Singapore, Singapore 169857, Singapore. Electronic address:

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May 2014

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.

Nature 2014 May 14;509(7501):503-6. Epub 2014 May 14.

Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-NUS Graduate Medical School Singapore, 8 College Road, 169857 Singapore.

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May 2014