David L Porter

David L Porter

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Innovation and Access at the Mercy of Payment Policy: The Future of Chimeric Antigen Receptor Therapies.

J Clin Oncol 2019 Nov 1:JCO1901691. Epub 2019 Nov 1.

University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.19.01691DOI Listing
November 2019

Accelerating chimeric antigen receptor therapy in chronic lymphocytic leukemia: The development and challenges of chimeric antigen receptor T-cell therapy for chronic lymphocytic leukemia.

Am J Hematol 2019 May 23;94(S1):S10-S17. Epub 2019 Mar 23.

Cell Therapy and Transplant Program, Division of Hematology-Oncology, Perelman School of Medicine and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.25457DOI Listing
May 2019

Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract.

Bone Marrow Transplant 2019 02 24;54(2):212-217. Epub 2018 May 24.

Blood and Marrow Transplantation Program, Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://www.nature.com/articles/s41409-018-0236-z
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http://dx.doi.org/10.1038/s41409-018-0236-zDOI Listing
February 2019

Prevention and treatment of relapse after stem cell transplantation in lymphoid malignancies.

Bone Marrow Transplant 2019 01 24;54(1):17-25. Epub 2018 May 24.

Division of Hematology Oncology, Blood and Marrow Transplant Program, University of Pennsylvania and Perelman School of Medicine, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41409-018-0214-5DOI Listing
January 2019

Early positron emission tomography/computed tomography as a predictor of response after CTL019 chimeric antigen receptor -T-cell therapy in B-cell non-Hodgkin lymphomas.

Cytotherapy 2018 12 29;20(12):1415-1418. Epub 2018 Oct 29.

Lymphoma Program at the Abramson Cancer Center and the Division of Hematology-Oncology Perelman School of Medicine, University of Pennsylvania, Pennsylvania, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14653249183063
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http://dx.doi.org/10.1016/j.jcyt.2018.10.003DOI Listing
December 2018

Higher Donor Apheresis Blood Volumes Are Associated with Reduced Relapse Risk and Improved Survival in Reduced-Intensity Allogeneic Transplantations with Unrelated Donors.

Biol Blood Marrow Transplant 2018 06 2;24(6):1203-1208. Epub 2018 Feb 2.

Blood and Marrow Transplantation Program and Columbia Center for Translational Immunology, Columbia University Medical Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2018.01.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993582PMC
June 2018

Pharmacodynamic Monitoring Predicts Outcomes of CCR5 Blockade as Graft-versus-Host Disease Prophylaxis.

Biol Blood Marrow Transplant 2018 03 20;24(3):594-599. Epub 2017 Oct 20.

Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Division of Hematology/Oncology and the Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826857PMC
March 2018

Erythropoietic protoporphyria in an adult with sequential liver and hematopoietic stem cell transplantation: A case report.

Am J Transplant 2018 03 9;18(3):745-749. Epub 2017 Dec 9.

Department of Medicine, Division of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/ajt.14581DOI Listing
March 2018

Toward dual hematopoietic stem-cell transplantation and solid-organ transplantation for sickle-cell disease.

Blood Adv 2018 03;2(5):575-585

Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1182/bloodadvances.2017012500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851417PMC
March 2018

Advances in CAR T-cell therapy for chronic lymphocytic leukemia.

Authors:
David L Porter

Clin Adv Hematol Oncol 2018 Feb;16(2):118-120

University of Pennsylvania Health System, Philadelphia, Pennsylvania.

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February 2018

Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation.

J Clin Oncol 2017 Dec 17;35(36):4003-4011. Epub 2017 Oct 17.

Robert J. Soiffer, Haesook T. Kim, Vincent T. Ho, Edwin P. Alyea, and Jerome Ritz, Dana-Farber Cancer Institute; James D. Levine, Beth Israel Deaconess Medical Center and Harvard Medical School; Yi-Bin Chen, Massachusetts General Hospital, Boston; Frank Glavin, Neovii Biotech, Lexington, MA; Joseph McGuirk, University of Kansas Medical Center, Kansas City, KS; Mitchell E. Horwitz, Duke University Medical Center, Durham; Thomas C. Shea, University of North Carolina School of Medicine, Chapel Hill, NC; Laura Johnston, Stanford University, Stanford, CA; Mrinal M. Patnaik, Mayo Clinic, Rochester, MN; Witold Rybka, Penn State College of Medicine, Hershey; David L. Porter, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Andrew Artz, University of Chicago, Chicago; Patrick J. Stiff, Loyola University Medical Center, Maywood, IL; Michael W. Boyer, University of Utah, Salt Lake City, UT; Richard T. Maziarz, Oregon Health & Science University, Portland, OR; Paul J. Shaughnessy, Texas Transplant Institute, San Antonio; Madhuri Vusirikala, University of Texas Southwestern Medical Center, Dallas, TX; Usama Gergis, Weill Cornell Medical College; Ran Reshef, Columbia University Medical Center, New York, NY; Hana Safah, Tulane University, New Orleans, LA; John F. DiPersio and Peter Westervelt, Washington University School of Medicine, St Louis, MO; Jeff Szer, Royal Melbourne Hospital, Parkville, Victoria; Ian D. Lewis, Royal Adelaide Hospital, Adelaide, South Australia, Australia; Jennifer Holter, University of Oklahoma Health Sciences Center, Oklahoma City, OK; Paul J. Martin, Fred Hutchinson Cancer Research Center, Seattle, WA; Joseph A. Pidala, H. Lee Moffitt Cancer Center, Tampa, FL; and Madan H. Jagasia, Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1200/JCO.2017.75.8177DOI Listing
December 2017

Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas.

N Engl J Med 2017 12 10;377(26):2545-2554. Epub 2017 Dec 10.

From the Lymphoma Program at the Abramson Cancer Center and the Division of Hematology-Oncology (S.J.S., J.S., E.A.C., S.D.N., A.R.M., D.L., D.L.P.), and the Department of Pathology and Laboratory Medicine (V.B., M.W., B.L.L., S.F.L., J.J.M., C.H.J.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Novartis Pharmaceuticals, Basel, Switzerland (Ö.A.); and Novartis Institutes for BioMedical Research, Cambridge, MA (J.L.B., I.P-M.).

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http://www.nejm.org/doi/10.1056/NEJMoa1708566
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http://dx.doi.org/10.1056/NEJMoa1708566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788566PMC
December 2017

The promise of chimeric antigen receptor T cells (CARTs) in leukaemia.

Br J Haematol 2017 04 15;177(1):13-26. Epub 2016 Dec 15.

Department of Hematology-Oncology, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.14475DOI Listing
April 2017

Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.

J Clin Oncol 2017 Apr 13;35(11):1154-1161. Epub 2017 Feb 13.

Bart L. Scott and H. Joachim Deeg, Fred Hutchinson Cancer Research Center, Seattle, WA; Marcelo C. Pasquini, Brent R. Logan, Mehdi Hamadani, and Mary M. Horowitz, Medical College of Wisconsin, Milwaukee, WI; Juan Wu and Adam M. Mendizabal, Emmes Corporation, Rockville, MD; Steven M. Devine, Ohio State University Comprehensive Cancer Center, Columbus, OH; David L. Porter, University of Pennsylvania, Philadelphia, PA; Richard T. Maziarz, Oregon Health and Science University, Portland, OR; Erica D. Warlick, University of Minnesota, Minneapolis; Jennifer Le-Rademacher, Mayo Clinic, Rochester, MN; Hugo F. Fernandez, Moffitt Cancer Center, Tampa, FL; Edwin P. Alyea, Dana Farber Cancer Institute, Boston, MA; Asad Bashey, Northside Hospital Cancer Institute, Atlanta, GA; Sergio Giralt, Memorial Sloan Kettering Cancer Center, New York, NY; Nancy L. Geller and Eric Leifer, National Heart, Lung, and Blood Institute, Bethesda, MD; and Mitchell E. Horwitz, Duke University, Durham, NC.

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http://dx.doi.org/10.1200/JCO.2016.70.7091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455603PMC
April 2017

Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

Crit Care Med 2017 Feb;45(2):e124-e131

1Division of Critical Care Medicine, Department of Anesthesia and Critical Care, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Division of Oncology, Department of Pediatrics, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 3Center for Cellular Immunotherapies, Department of Pathology and Laboratory Medicine, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 4Department of Biostatistics and Epidemiology, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 5Division of Hematology-Oncology, Department of Medicine, Abramson Cancer Center, The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000002053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452983PMC
February 2017

Chimeric Antigen Receptor T Cells and Hematopoietic Cell Transplantation: How Not to Put the CART Before the Horse.

Biol Blood Marrow Transplant 2017 Feb 13;23(2):235-246. Epub 2016 Sep 13.

Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, Pennsylvania; Division of Hematology/Oncology, University of Pennsylvania School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Abramson Cancer Center, University of Pennsylvania School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237606PMC
February 2017

Cytokine release syndrome with novel therapeutics for acute lymphoblastic leukemia.

Hematology Am Soc Hematol Educ Program 2016 Dec;2016(1):567-572

Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1182/asheducation-2016.1.567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142489PMC
December 2016

Clinical Utility of Next-Generation Sequencing for Oncogenic Mutations in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation.

Biol Blood Marrow Transplant 2016 11 28;22(11):1961-1967. Epub 2016 Jul 28.

Blood and Marrow Transplantation Program and Columbia Center for Translational Immunology, Department of Medicine, Columbia University Medical Center, New York, New York. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067228PMC
http://dx.doi.org/10.1016/j.bbmt.2016.07.018DOI Listing
November 2016

The Promise of Chimeric Antigen Receptor T-Cell Therapy.

Oncology (Williston Park) 2016 10;30(10):880-8, 890

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October 2016

Nelarabine, cyclosphosphamide and etoposide for adults with relapsed T-cell acute lymphoblastic leukaemia and lymphoma.

Br J Haematol 2016 07 25;174(2):332-4. Epub 2015 Sep 25.

Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.13771DOI Listing
July 2016

Autologous stem cell transplantation in first complete remission may not extend progression-free survival in patients with peripheral T cell lymphomas.

Am J Hematol 2016 07 24;91(7):672-6. Epub 2016 Apr 24.

Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.24372DOI Listing
July 2016

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia.

Cancer Discov 2016 06 13;6(6):664-79. Epub 2016 Apr 13.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Abramson Cancer Center, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Department of Pathology and Laboratory Medicine, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448406PMC
June 2016

Chimeric antigen receptor T cell therapy: 25years in the making.

Blood Rev 2016 05 6;30(3):157-67. Epub 2015 Nov 6.

Division of Hematology/Oncology, University of Pennsylvania Health System, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.blre.2015.10.003DOI Listing
May 2016

CAR T-cells merge into the fast lane of cancer care.

Am J Hematol 2016 Jan;91(1):146-50

Division of Hematology Oncology, University of Pennsylvania, 3400 Civic Center Boulevard, PCAM 2 West Pavilion, Philadelphia, Pennsylvania, 19104.

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http://dx.doi.org/10.1002/ajh.24238DOI Listing
January 2016

Novel treatments for chronic lymphocytic leukemia and moving forward.

Am Soc Clin Oncol Educ Book 2014 :e317-25

From the Chronic Lymphocytic Leukemia Center, Dana-Farber Cancer Institute, Boston, MA; Blood and Marrow Transplantation, Hospital of the University of Pennsylvania, Philadelphia, PA; Department of Leukemia, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.e317DOI Listing
December 2015

Evolution to plasmablastic lymphoma evades CD19-directed chimeric antigen receptor T cells.

Br J Haematol 2015 Oct 18;171(2):205-209. Epub 2015 Jun 18.

Department of Medicine and James P. Wilmot Cancer Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

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http://dx.doi.org/10.1111/bjh.13562DOI Listing
October 2015

Outpatient Autologous Stem Cell Transplantation for Patients With Myeloma.

Clin Lymphoma Myeloma Leuk 2015 Sep 6;15(9):536-40. Epub 2015 Jun 6.

Hematologic Malignancies and Bone Marrow Transplant Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2015.05.006DOI Listing
September 2015

Lack of a significant pharmacokinetic interaction between maraviroc and tacrolimus in allogeneic HSCT recipients.

J Antimicrob Chemother 2015 Jul 16;70(7):2078-83. Epub 2015 Apr 16.

Abramson Cancer Center and the Division of Hematology and Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

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http://dx.doi.org/10.1093/jac/dkv082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472330PMC
July 2015

A drive through cellular therapy for CLL in 2015: allogeneic cell transplantation and CARs.

Blood 2015 Jul 11;126(4):478-85. Epub 2015 Jun 11.

Division of Hematology/Oncology, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1182/blood-2015-03-585091DOI Listing
July 2015

Voriconazole-induced periostitis after allogeneic stem cell transplantation.

Am J Hematol 2015 Jun 29;90(6):574-5. Epub 2015 Apr 29.

Division of Hematology Oncology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.23977DOI Listing
June 2015

CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia.

Blood 2015 Jun 21;125(26):4017-23. Epub 2015 May 21.

Division of Oncology, The Children's Hospital of Philadelphia, Department of Pediatrics, Department of Pathology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1182/blood-2014-12-580068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481592PMC
June 2015

R-CHOP or R-HyperCVAD with or without autologous stem cell transplantation for older patients with mantle cell lymphoma.

Clin Lymphoma Myeloma Leuk 2015 Feb 1;15(2):92-7. Epub 2014 Aug 1.

Division of Hematology and Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2014.07.017DOI Listing
February 2015

Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced-intensity conditioning.

Biol Blood Marrow Transplant 2014 Nov 10;20(11):1758-66. Epub 2014 Jul 10.

Abramson Cancer Center and the Division of Hematology & Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.bbmt.2014.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194246PMC
November 2014

Chimeric antigen receptor T cells for sustained remissions in leukemia.

N Engl J Med 2014 Oct;371(16):1507-17

From the Division of Oncology, Children's Hospital of Philadelphia (S.L.M., R.A., D.M.B., N.J.B., S.R.R., D.T.T., S.A.G.), the Departments of Pediatrics (S.L.M., R.A., D.M.B., N.J.B., S.R.R., D.T.T., S.A.G.), Biostatistics and Epidemiology (P.A.S., R.A.), and Pathology and Laboratory Medicine (J.J.M., B.L.L., C.H.J., S.A.G.), the Division of Hematology-Oncology (N.F., D.L.P.), and Abramson Cancer Center (N.F., A.C., V.E.G., Z.Z., S.F.L., Y.D.M., J.J.M., B.L.L., C.H.J., D.L.P., S.A.G.), Perelman School of Medicine, University of Pennsylvania - all in Philadelphia; and Novartis Pharmaceuticals, East Hanover, NJ (A.S.).

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http://dx.doi.org/10.1056/NEJMoa1407222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267531PMC
October 2014

Chimeric antigen receptor therapy for cancer.

Annu Rev Med 2014 20;65:333-47. Epub 2013 Nov 20.

Abramson Cancer Center and the Departments of Medicine, Pediatrics, and Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; email:

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http://dx.doi.org/10.1146/annurev-med-060512-150254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120077PMC
September 2014

Engineered T cells for cancer therapy.

Cancer Immunol Immunother 2014 Sep 19;63(9):969-75. Epub 2014 Jun 19.

Abramson Cancer Center, University of Pennsylvania, 3400 Civic Center Boulevard, 8th Floor, Philadelphia, PA, 19104-5156, USA,

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http://dx.doi.org/10.1007/s00262-014-1568-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142345PMC
September 2014

Improved survival after transplantation of more donor plasmacytoid dendritic or naïve T cells from unrelated-donor marrow grafts: results from BMTCTN 0201.

J Clin Oncol 2014 Aug 30;32(22):2365-72. Epub 2014 Jun 30.

Edmund K. Waller and Wayne A.C. Harris, Emory University, Atlanta, GA; Brent R. Logan, Medical College of Wisconsin, Milwaukee, WI; Steven M. Devine, Ohio State University, Columbus, OH; David L. Porter, University of Pennsylvania, Philadelphia, PA; Shin Mineishi, University of Alabama at Birmingham, Birmingham, AL; John M. McCarty, Medical College of Virginia, Richmond, VA; Corina E. Gonzalez, Georgetown University Hospital, Washington, DC; Thomas R. Spitzer, Massachusetts General Hospital, Boston, MA; Oleg I. Krijanovski, Sutter East Bay Medical Foundation, Berkeley, CA; Michael L. Linenberger and Ann Woolfrey, Fred Hutchinson Cancer Research Center, Seattle, WA; Alan Howard and Dennis L. Confer, National Marrow Donor Program, Minneapolis, MN; Juan Wu, EMMES Corporation, Rockville, MD; and Claudio Anasetti, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.

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http://dx.doi.org/10.1200/JCO.2013.54.4577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180368PMC
August 2014

CAR-modified anti-CD19 T cells for the treatment of B-cell malignancies: rules of the road.

Expert Opin Biol Ther 2014 Jan 21;14(1):37-49. Epub 2013 Nov 21.

University of Pennsylvania, Abramson Cancer Center, Perelman School of Medicine, Division of Hematology-Oncology, Department of Medicine , Philadelphia, PA 19106 , USA

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http://dx.doi.org/10.1517/14712598.2014.860442DOI Listing
January 2014

Cytogenetics of a parthenogenetic Arctic species of Micropsectra (Diptera, Chironomidae).

Comp Cytogenet 2011 9;5(4):315-28. Epub 2011 Nov 9.

Department of Genetics, The University of Melbourne VIC 3010, Australia.

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http://dx.doi.org/10.3897/CompCytogen.v5i4.1356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833782PMC
November 2013

Receipt of maintenance therapy is most predictive of survival in older acute lymphoblastic leukemia patients treated with intensive induction chemotherapy regimens.

Am J Hematol 2013 Aug 5;88(8):657-60. Epub 2013 Jun 5.

Division of Hematology/Oncology, Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/ajh.23468DOI Listing
August 2013

Reduced-intensity hematopoietic stem cell transplants for malignancies: harnessing the graft-versus-tumor effect.

Annu Rev Med 2013 29;64:101-17. Epub 2012 Oct 29.

Abramson Cancer Center, Department of Medicine, Perelman School of Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1146/annurev-med-121411-103452DOI Listing
July 2013

A classic presentation of an uncommon leukemia.

Am J Hematol 2013 May 17;88(5):431-2. Epub 2012 Sep 17.

Department of Internal Medicine, Division of Hematology/Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/ajh.23325DOI Listing
May 2013

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.

N Engl J Med 2013 Apr 25;368(16):1509-1518. Epub 2013 Mar 25.

Children's Hospital of Philadelphia (S.A.G., D.B., R.A., S.R.R., D.T.T., B.H., J.F.W.); the Department of Pediatrics (S.A.G., D.B., R.A., S.R.R., D.T.T.), Abramson Cancer Center (S.A.G., M.K., R.A., D.L.P., S.R.R., D.T.T., M.C.M., B.L.L., C.H.J.); and the Departments of Pathology and Laboratory Medicine (M.K., A.C., B.H., J.F.W., M.C.M., B.L.L., C.H.J.) and Medicine (D.L.P.), University of Pennsylvania - all in Philadelphia.

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http://dx.doi.org/10.1056/NEJMoa1215134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058440PMC
April 2013

Allogeneic immunotherapy to optimize the graft-versus-tumor effect: concepts and controversies.

Authors:
David L Porter

Hematology Am Soc Hematol Educ Program 2011 ;2011:292-8

Division of Hematology-Oncology, Blood and Marrow Transplant Program, University of Pennsylvania Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1182/asheducation-2011.1.292DOI Listing
April 2012

An inhibitor of eIF2 activity in the sRNA pool of eukaryotic cells.

Gene 2011 Aug 27;482(1-2):15-23. Epub 2011 May 27.

Department of Surgery, Yale University School of Medicine, New Haven, CT 06520-8041, USA.

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http://dx.doi.org/10.1016/j.gene.2011.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426319PMC
August 2011

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.

N Engl J Med 2011 Aug 10;365(8):725-33. Epub 2011 Aug 10.

Abramson Cancer Center, and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa1103849
Publisher Site
http://dx.doi.org/10.1056/NEJMoa1103849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387277PMC
August 2011

Chimeric Antigen Receptor Therapy for B-cell Malignancies.

J Cancer 2011 1;2:331-2. Epub 2011 Jun 1.

1. Abramson Cancer Center, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119397PMC
http://dx.doi.org/10.7150/jca.2.331DOI Listing
July 2011

Cellular adoptive immunotherapy after autologous and allogeneic hematopoietic stem cell transplantation.

Cancer Treat Res 2009 ;144:497-537

Division of Hematology-Oncology, University of Pennsylvania Medical Center, 16 Penn Tower, 3400 Spruce St, Philadelphia, PA, USA.

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http://link.springer.com/10.1007/978-0-387-78580-6_20
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http://dx.doi.org/10.1007/978-0-387-78580-6_20DOI Listing
September 2010

Allogeneic immunotherapy to optimize the graft-versus-tumor effect: concepts and controversies.

Expert Rev Hematol 2010 Jun;3(3):301-14

Division of Hematology-Oncology/BMT, Abramson Cancer Center, University of Pennsylvania Medical Center, 2 Perelman, 3400 Civic Center Blvd, Philadelphia, PA, USA.

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http://www.tandfonline.com/doi/full/10.1586/ehm.10.29
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June 2010

Relapse after allogeneic hematopoietic cell therapy.

Biol Blood Marrow Transplant 2010 Jan 24;16(1 Suppl):S138-45. Epub 2009 Oct 24.

Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1016/j.bbmt.2009.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637945PMC
January 2010

Circulating osteogenic precursor cells in heterotopic bone formation.

Stem Cells 2009 Sep;27(9):2209-19

Department of Medicine, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1002/stem.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496263PMC
September 2009

Functional unresponsiveness and replicative senescence of myeloid leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation.

Clin Cancer Res 2009 Aug 14;15(15):4944-53. Epub 2009 Jul 14.

Abramson Family Cancer Research Institute, Abramson Cancer Center, Department of Pathology and Laboratory Medicine, Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-3332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722844PMC
August 2009

Graft-versus-host disease after donor leukocyte infusions: presentation and management.

Best Pract Res Clin Haematol 2008 Jun;21(2):205-22

Division of Hematology-Oncology and Abramson Cancer Center, University of Pennsylvania Medical Center, 16 Penn Tower, 3400 ISpruce St, Philadelphia PA 19106, USA.

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http://dx.doi.org/10.1016/j.beha.2008.02.007DOI Listing
June 2008

Cutaneous Hodgkin's disease.

J Am Acad Dermatol 2008 Feb;58(2):295-8

Department of Dermatology, the University of Pennsylvania, Philadelphia, USA.

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February 2008