Publications by authors named "David L Huso"

102Publications

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

Cell Host Microbe 2018 Feb 1;23(2):203-214.e5. Epub 2018 Feb 1.

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA. Electronic address:

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February 2018

HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche.

Nat Commun 2017 04 28;8:15008. Epub 2017 Apr 28.

Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Room 1025, Baltimore, Maryland 21205, USA.

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April 2017

A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.

Proc Natl Acad Sci U S A 2017 01 20;114(1):125-130. Epub 2016 Dec 20.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

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January 2017

Constitutive renal Rel/nuclear factor-κB expression in Lewis polycystic kidney disease rats.

World J Nephrol 2016 Jul;5(4):339-57

Michelle HT Ta, Kristina G Schwensen, David Liuwantara, Gopala K Rangan, Centre for Transplant and Renal Research, Westmead Institute for Medical Research, the University of Sydney, Sydney 2145, Australia.

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July 2016

Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease.

Kidney Int 2016 07 25;90(1):90-9. Epub 2016 Mar 25.

Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA. Electronic address:

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July 2016

The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.

Gynecol Oncol 2016 06 8;141(3):580-587. Epub 2016 Apr 8.

Hematology Division, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Pathobiology Graduate Program, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD, United States; Institute for Cellular Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address:

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June 2016

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.

Cancer Res 2016 04 15;76(8):2115-24. Epub 2016 Feb 15.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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April 2016

Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis.

Cancer Discov 2015 Oct 22;5(10):1098-109. Epub 2015 Jul 22.

Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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October 2015

Novel inhibitors of nuclear transport cause cell cycle arrest and decrease cyst growth in ADPKD associated with decreased CDK4 levels.

Am J Physiol Renal Physiol 2014 Dec 18;307(11):F1179-86. Epub 2014 Sep 18.

Graduate Group in Comparative Pathology, Division of Nephrology, Department of Internal Medicine, and Cancer Center, University of California, Davis, California; Medical Service, Sacramento Veterans Affairs Medical Center, Sacramento, California

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December 2014

Polycystin signaling is required for directed endothelial cell migration and lymphatic development.

Cell Rep 2014 May 24;7(3):634-44. Epub 2014 Apr 24.

Division of Nephrology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address:

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May 2014