Publications by authors named "David Kleiner"

100Publications

In Utero SARS-CoV-2 Infection.

J Pediatric Infect Dis Soc 2020 Oct 22. Epub 2020 Oct 22.

Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/jpids/piaa127DOI Listing
October 2020

Expert Panel Review on Non-Alcoholic Fatty Liver Disease in Persons with HIV.

Clin Gastroenterol Hepatol 2020 Oct 15. Epub 2020 Oct 15.

Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2020.10.018DOI Listing
October 2020

Risk Factors for Delta Hepatitis in a North American Cohort: Who Should Be Screened?

Am J Gastroenterol 2020 Oct 7. Epub 2020 Oct 7.

1Liver Diseases Branch, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA; 2Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.14309/ajg.0000000000000954DOI Listing
October 2020

The Clinical Spectrum and Diagnosis of Oxaliplatin Liver Injury in the Era of Non-alcoholic Fatty Liver Disease.

Clin Gastroenterol Hepatol 2020 Sep 29. Epub 2020 Sep 29.

FDA, CDER/OND/OII, Division of Hepatology and Nutrition, Silver Spring, MD. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2020.09.038DOI Listing
September 2020

Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis.

Redox Biol 2020 Sep 1;37:101710. Epub 2020 Sep 1.

Liver and Energy Metabolism Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA; Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2020.101710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494510PMC
September 2020

4-HNE Immunohistochemistry and Image Analysis for Detection of Lipid Peroxidation in Human Liver Samples Using Vitamin E Treatment in NAFLD as a Proof of Concept.

J Histochem Cytochem 2020 Sep;68(9):635-643

Liver and Energy Metabolism Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases.

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http://dx.doi.org/10.1369/0022155420946402DOI Listing
September 2020

Fifty years of impact on liver pathology: a history of the Gnomes.

Virchows Arch 2020 Jun 30. Epub 2020 Jun 30.

Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK.

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http://dx.doi.org/10.1007/s00428-020-02879-5DOI Listing
June 2020

Cryptosporidium infection in dedicator of cytokinesis 8 (DOCK 8) deficiency.

J Allergy Clin Immunol Pract 2020 Jun 22. Epub 2020 Jun 22.

Translational Hepatology Section, Liver Diseases Branch, NIDDK, NIH, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.06.021DOI Listing
June 2020

Automated quantification and architectural pattern detection of hepatic fibrosis in NAFLD.

Ann Diagn Pathol 2020 Aug 12;47:151518. Epub 2020 Apr 12.

Department of Computer and Information Science, Indiana University Purdue University, Indianapolis, IN, United States of America.

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http://dx.doi.org/10.1016/j.anndiagpath.2020.151518DOI Listing
August 2020

The first malignant primary hepatic glomus tumor: A case report.

Int J Surg Case Rep 2020 11;70:197-200. Epub 2020 May 11.

Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijscr.2020.04.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229426PMC
May 2020

Elevated liver stiffness without histological evidence of liver fibrosis in rural Ugandans.

J Viral Hepat 2020 Oct 9;27(10):1022-1031. Epub 2020 Jun 9.

Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/jvh.13320DOI Listing
October 2020

Hepatic Histology in Treatment-naïve Children With Chronic Hepatitis B Infection Living in the United States and Canada.

J Pediatr Gastroenterol Nutr 2020 07;71(1):99-105

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/MPG.0000000000002712DOI Listing
July 2020

Platelet-derived growth factor receptor-alpha-positive myeloid neoplasm presenting as eosinophilic gastrointestinal disease.

J Allergy Clin Immunol Pract 2020 Jun 12;8(6):2089-2091. Epub 2020 Feb 12.

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.01.055DOI Listing
June 2020

Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH.

Hepatology 2020 Jan 21. Epub 2020 Jan 21.

NAFLD Research Center, Division of Gastroenterology and Hepatology Department of Medicine, University of California San Diego, La Jolla, CA.

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http://dx.doi.org/10.1002/hep.31121DOI Listing
January 2020

Intrahepatic cholangiocarcinoma as a rare secondary malignancy after allogeneic hematopoietic stem cell transplantation for childhood acute lymphoblastic leukemia: A case report.

Pediatr Transplant 2020 03 16;24(2):e13653. Epub 2020 Jan 16.

Surgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/petr.13653DOI Listing
March 2020

The Delta-4 fibrosis score (D4FS): A novel fibrosis score in chronic hepatitis D.

Antiviral Res 2020 02 16;174:104691. Epub 2019 Dec 16.

Liver Diseases Branch, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2019.104691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560973PMC
February 2020

Liver Histology: Diagnostic and Prognostic Features.

Clin Liver Dis 2020 02 31;24(1):61-74. Epub 2019 Oct 31.

Post-Mortem Section, Laboratory of Pathology, National Cancer Institute, 10 Center Drive, Building 10, Room 2S235, MSC1500, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2019.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986808PMC
February 2020

Vibration-controlled transient elastography for the detection of cirrhosis in chronic hepatitis D infection.

J Viral Hepat 2020 Apr 9;27(4):428-436. Epub 2019 Dec 9.

Liver Diseases Branch, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/jvh.13235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080586PMC
April 2020

Complete Pathological Response to Crizotinib in a Patient with ALK-rearranged Lung Adenocarcinoma.

Clin Lung Cancer 2020 01 13;21(1):e25-e29. Epub 2019 Oct 13.

Thoracic Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1016/j.cllc.2019.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996866PMC
January 2020

Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer.

Cancer Cell 2019 10 3;36(4):418-430.e6. Epub 2019 Oct 3.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA; Liver Cancer Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801104PMC
October 2019

Reply.

Hepatology 2019 12;70(6):2241-2242

National Cancer Institute.

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http://dx.doi.org/10.1002/hep.30901DOI Listing
December 2019

Exploring the Link Between Platelet Numbers and Vascular Homeostasis Across Early and Late Stages of Fibrosis in Hepatitis C.

Dig Dis Sci 2020 02 12;65(2):524-533. Epub 2019 Aug 12.

Translational Hepatology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Building 10, Room 9B16, 10 Center Dr. MSC 1800, Bethesda, MD, 20892-1800, USA.

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http://dx.doi.org/10.1007/s10620-019-05760-xDOI Listing
February 2020

Bacterial Translocation and Host Immune Activation in Chronic Hepatitis C Infection.

Open Forum Infect Dis 2019 Jul;6(7)

Translational Hepatology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1093/ofid/ofz255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667717PMC
July 2019

Portal Pressure in Noncirrhotic Portal Hypertension: To Measure or Not to Measure.

Hepatology 2019 12 9;70(6):2228-2230. Epub 2019 Oct 9.

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1002/hep.30862DOI Listing
December 2019

Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B.

Viruses 2019 04 25;11(4). Epub 2019 Apr 25.

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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https://www.mdpi.com/1999-4915/11/4/386
Publisher Site
http://dx.doi.org/10.3390/v11040386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520809PMC
April 2019

Hepatic Manifestations of Cystic Fibrosis.

Clin Liver Dis 2019 05 21;23(2):263-277. Epub 2019 Feb 21.

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 Center Drive, Building 10, Room 9B-16, MSC 1800, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cld.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452885PMC
May 2019

The Spectrum of Hepatic Involvement in Patients With Telomere Disease.

Hepatology 2019 06 10;69(6):2579-2585. Epub 2019 Apr 10.

Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1002/hep.30578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440774PMC
June 2019

The balance of type 1 and type 2 immune responses in the contexts of hepatitis B infection and hepatitis D infection.

J Gastroenterol Hepatol 2019 Apr 25;34(4):764-775. Epub 2019 Feb 25.

Liver Diseases Branch, National Institute of Diabetes, Digestive, and Kidney Diseases, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/jgh.14617DOI Listing
April 2019

The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma.

Cancer Immunol Immunother 2019 Apr 28;68(4):599-608. Epub 2019 Jan 28.

Gastrointestinal Malignancies Section, Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Building 10, Room 3B43, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s00262-019-02299-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662600PMC
April 2019

Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma.

Mol Cancer Res 2018 09 1;16(9):1406-1419. Epub 2018 Jun 1.

Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0012DOI Listing
September 2018

Recent Advances in the Histopathology of Drug-Induced Liver Injury.

Authors:
David E Kleiner

Surg Pathol Clin 2018 Jun;11(2):297-311

Laboratory of Pathology, National Cancer Institute, 10 Center Drive, Building 10, Room 2S235, MSC1500, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.path.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953206PMC
June 2018

Mounier-Kuhn Syndrome Mimicking Lymphangioleiomyomatosis.

Chest 2018 02;153(2):e19-e23

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692173297
Publisher Site
http://dx.doi.org/10.1016/j.chest.2017.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026286PMC
February 2018

Hepatocellular carcinoma: Liver biopsy in the balance.

Authors:
David E Kleiner

Hepatology 2018 07;68(1):13-15

Laboratory of Pathology, National Cancer Institute, Bethesda, MD.

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http://dx.doi.org/10.1002/hep.29831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033634PMC
July 2018

Three variants in the nicotinamide adenine dinucleotide phosphate oxidase complex are associated with HCV-related liver damage.

Hepatol Commun 2017 11 23;1(9):973-982. Epub 2017 Oct 23.

Translational Hepatology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health Bethesda MD.

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http://dx.doi.org/10.1002/hep4.1103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721460PMC
November 2017

Liver disturbances in activated phosphoinositide 3-kinase δ syndrome.

J Allergy Clin Immunol Pract 2018 Sep - Oct;6(5):1763-1765. Epub 2018 Feb 16.

Translational Hepatology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Md.

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http://dx.doi.org/10.1016/j.jaip.2018.01.005DOI Listing
November 2019

Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy.

Neurology 2017 Dec 15;89(24):2481-2490. Epub 2017 Nov 15.

From the Neurogenetics Branch (R.D.G., A.K., D.A.F., I.K., D.B., K.H.F., C.G.), National Institute of Neurological Disorders and Stroke; Liver Diseases Branch (V.T., H.A., Y.R.), National Institute of Diabetes and Digestive and Kidney Diseases; Cardiovascular and Pulmonary Branch (A.T.R.), National Heart Lung & Blood Institute; Laboratory of Pathology (S.M.H., D.E.K.), National Cancer Institute; Radiology and Imaging Sciences (C.-Y.L.), Clinical Center, National Institute of Allergy and Infectious Diseases; and NIH (C.H.), Bethesda, MD.

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http://dx.doi.org/10.1212/WNL.0000000000004748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729799PMC
December 2017

Identification and Characterization of Fenofibrate-Induced Liver Injury.

Dig Dis Sci 2017 12 8;62(12):3596-3604. Epub 2017 Nov 8.

Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s10620-017-4812-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694705PMC
December 2017

Histopathology, grading and staging of nonalcoholic fatty liver disease.

Authors:
David E Kleiner

Minerva Gastroenterol Dietol 2018 Mar 25;64(1):28-38. Epub 2017 Sep 25.

Laboratory of Pathology, National Cancer Institute, Bethesda, MD, USA -

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http://dx.doi.org/10.23736/S1121-421X.17.02445-XDOI Listing
March 2018

The Role of the Hepatopathologist in the Assessment of Drug-induced Liver Injury.

Authors:
David E Kleiner

Clin Liver Dis (Hoboken) 2017 Feb 1;9(2):34-37. Epub 2017 Mar 1.

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http://dx.doi.org/10.1002/cld.612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604852PMC
February 2017

Histopathological challenges in suspected drug-induced liver injury.

Authors:
David E Kleiner

Liver Int 2018 02 19;38(2):198-209. Epub 2017 Sep 19.

Post-Mortem Section, Laboratory of Pathology, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/liv.13584DOI Listing
February 2018

Drug-induced Liver Injury: The Hepatic Pathologist's Approach.

Authors:
David E Kleiner

Gastroenterol Clin North Am 2017 06;46(2):273-296

Laboratory of Pathology, National Cancer Institute, 10 Center Drive, Building 10, Room 2S235, MSC 1500, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gtc.2017.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434713PMC
June 2017