David Klatzmann

David Klatzmann

UNVERIFIED PROFILE

Are you David Klatzmann?   Register this Author

Register author
David Klatzmann

David Klatzmann

Publications by authors named "David Klatzmann"

Are you David Klatzmann?   Register this Author

100Publications

2854Reads

35Profile Views

RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy.

Front Immunol 2018 15;9:1038. Epub 2018 May 15.

Sorbonne Université, INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2018.01038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962720PMC
July 2019

TLR9 signalling in HCV-associated atypical memory B cells triggers Th1 and rheumatoid factor autoantibody responses.

J Hepatol 2019 Jul 4. Epub 2019 Jul 4.

Sorbonne Université, INSERM UMR_S 959, Immunologie-Immunopathologie-Immunotherapie, i3 and Département Hospitalo-Universitaire Inflammation-Immunopathologie-Biotherapie, i2B, F-75651 Paris, France; AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Service de Biothérapie, F-75013 Paris, France; AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2019.06.029DOI Listing
July 2019

T regulatory cells activation and distribution are modified in critically ill patients with acute respiratory distress syndrome: A prospective single-centre observational study.

Anaesth Crit Care Pain Med 2019 Jul 30. Epub 2019 Jul 30.

Multidisciplinary Intensive Care Unit, Department of Anaesthesiology and Critical Care, La Pitié-Salpêtrière Hospital, Public Hospitals of Paris (AP-HP), Sorbonne University, 75013 Paris, France; Public Hospitals of Paris (AP-HP), La Pitié-Salpêtrière Hospital, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), 75651 Paris, France; Sorbonne University, INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (i3), 75651 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.accpm.2019.07.014DOI Listing
July 2019

Role of Chemokine Receptor CCR4 and Regulatory T Cells in Wound Healing of Diabetic Mice.

J Invest Dermatol 2019 May 19;139(5):1161-1170. Epub 2018 Nov 19.

Institute of Biomedical Sciences, Pharmacology and Inflammation Program, Federal University of Rio de Janeiro, Center for Health Sciences, Rio de Janeiro, Rio de Janeiro, Brazil; Institute of Biophysics Carlos Chagas Filho, Immunobiology Program, Federal University of Rio de Janeiro, Center for Health Sciences, Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2018.10.039DOI Listing
May 2019

Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells.

Front Immunol 2019 27;10:250. Epub 2019 Feb 27.

Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.00250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402473PMC
February 2019

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.

Nat Commun 2019 01 21;10(1):361. Epub 2019 Jan 21.

Centro de Investigación y Desarrollo en Inmunología y Enfermedades Infecciosas (CIDIE), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)/Universidad Católica de Córdoba (UCC), Córdoba, X5016DHK, Argentina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-08265-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341118PMC
January 2019

Regulatory T cells in the treatment of disease.

Nat Rev Drug Discov 2018 11 12;17(11):823-844. Epub 2018 Oct 12.

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1038/nrd.2018.148
Publisher Site
http://dx.doi.org/10.1038/nrd.2018.148DOI Listing
November 2018

Pharmacodynamics of regulatory T cells in mice and humans treated with low-dose IL-2.

J Allergy Clin Immunol 2018 10 18;142(4):1344-1346.e3. Epub 2018 Jun 18.

AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation- Immunopathology-Biotherapy Department (i2B), Paris, France; Sorbonne Université, UPMC Univ Paris 06, Immunology-Immunopathology-Immunotherapy (I3), Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2018.06.006DOI Listing
October 2018

A standardized flow cytometry procedure for the monitoring of regulatory T cells in clinical trials.

Cytometry B Clin Cytom 2018 09 23;94(5):621-626. Epub 2018 Jan 23.

Sorbonne Université, UPMC Univ Paris 06, INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (I3), Paris F-75005, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cyto.b.21622DOI Listing
September 2018

IL-2 antibodies in type 1 diabetes and during IL-2 therapy.

Diabetologia 2018 09 2;61(9):2066-2068. Epub 2018 Jun 2.

AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00125-018-4649-4DOI Listing
September 2018

High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells.

Proc Natl Acad Sci U S A 2018 09 29;115(38):9604-9609. Epub 2018 Aug 29.

Immunology-Immunopathology-Immunotherapy Laboratory, UMR_S 959, INSERM, Sorbonne Université, F-75005 Paris, France;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1808594115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156623PMC
September 2018

Deep phenotyping of immune cell populations by optimized and standardized flow cytometry analyses.

Cytometry A 2018 08 31;93(8):793-802. Epub 2018 Aug 31.

Sorbonne Universités, UPMC Univ Paris 06, INSERM, UMR S 959, Immunology-Immunopathology- Immunotherapy (I3), F-75005, Paris, France.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/cyto.a.23570
Publisher Site
http://dx.doi.org/10.1002/cyto.a.23570DOI Listing
August 2018

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction.

Nat Commun 2018 06 26;9(1):2432. Epub 2018 Jun 26.

Department of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy and Center for Translational Cardiology, Azienda Sanitaria Universitaria Integrata di Trieste, 34129, Trieste, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-04908-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018668PMC
June 2018

Regulatory T Cells As Supporters of Psychoimmune Resilience: Toward Immunotherapy of Major Depressive Disorder.

Front Neurol 2018 20;9:167. Epub 2018 Mar 20.

Sorbonne Université, INSERM, Immunology-Immunopathology-Immunotherapy (i3), AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2018.00167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869201PMC
March 2018

A Sophism in Vectorology: Turning Harmful Defective Retroviral Vectors into Helpful Replication-Competent Retroviruses Against Cancer.

Authors:
David Klatzmann

Hum Gene Ther 2017 11;28(11):954-957

1 Sorbonne Université, University Pierre and Marie Curie (UPMC) , Univ Paris 06, INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/hum.2017.29050.dklDOI Listing
November 2017

The early pregnancy placenta foreshadows DNA methylation alterations of solid tumors.

Epigenetics 2017 09 24;12(9):793-803. Epub 2017 Nov 24.

f Massachusetts General Hospital and Harvard Medical School , Department of Pathology and Center for Cancer Research , Charlestown , Massachusetts , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15592294.2017.1342912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739102PMC
September 2017

T cells lack IL-2Rα but express decoy IL-1R2 and IL-1Ra and suppress the IL-1-dependent activation of T cells.

Sci Immunol 2017 Sep;2(15)

Sorbonne Université, University Pierre and Marie Curie (UPMC), Univ Paris 06, INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (i3), F-75005 Paris, France.

View Article

Download full-text PDF

Source
http://immunology.sciencemag.org/lookup/doi/10.1126/sciimmun
Publisher Site
http://dx.doi.org/10.1126/sciimmunol.aan0368DOI Listing
September 2017

B- and T-cell subpopulations in patients with severe idiopathic membranous nephropathy may predict an early response to rituximab.

Kidney Int 2017 07 15;92(1):227-237. Epub 2017 Mar 15.

Sorbonne Universités, UPMC Univ Paris, Paris, France; INSERM, UMR_S 1155, Paris, France; AP-HP, Hôpital Tenon, Department of Nephrology and Dialysis, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.kint.2017.01.012DOI Listing
July 2017

Reply: Beneficial effect of interleukin-2-based immunomodulation in Alzheimer-like pathology.

Brain 2017 07;140(7):e40

INSERM U1169/MIRCen CEA 92265 Fontenay aux Roses and Université Paris-Sud, Université Paris Saclay, 91400 Orsay, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awx109DOI Listing
July 2017

Direct-Acting Antiviral Therapy Restores Immune Tolerance to Patients With Hepatitis C Virus-Induced Cryoglobulinemia Vasculitis.

Gastroenterology 2017 06 6;152(8):2052-2062.e2. Epub 2017 Mar 6.

Département Hospitalo-Universitaire Inflammation-Immunopathologie-Biotherapie (département hospitalo-unniversitaire i2B), Sorbonne Universités, Université Pierre et Marie Curie Université Paris 06, unité mixte de recherche 7211, Paris, France; INSERM, unité mixte de recherche_S 959, Paris, France; centre national de recherche et de santé, FRE3632, Paris, France; Département de Médecine Interne et Immunologie Clinique, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2017.02.037DOI Listing
June 2017

T cells and autoimmune kidney disease.

Nat Rev Nephrol 2017 06 13;13(6):329-343. Epub 2017 Mar 13.

Division of Rheumatology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, CLS-937, Boston, Massachusetts 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrneph.2017.34DOI Listing
June 2017

Regulatory T Cell Therapy for Uveitis: A New Promising Challenge.

J Ocul Pharmacol Ther 2017 05;33(4):278-284

3 Department of Ophthalmology, DHU ViewMaintain, Pitié-Salpêtrière Hospital , Paris, France .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jop.2016.0165DOI Listing
May 2017

T follicular helper and T follicular regulatory cells have different TCR specificity.

Nat Commun 2017 04 21;8:15067. Epub 2017 Apr 21.

Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms15067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413949PMC
April 2017

Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice.

Brain 2017 03;140(3):826-842

INSERM U1169/MIRCen CEA 92265 Fontenay aux Roses and Université Paris-Sud, Université Paris Saclay, 91400 Orsay, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/aww330DOI Listing
March 2017

Behçet's disease physiopathology: a contemporary review.

Auto Immun Highlights 2016 Dec 12;7(1). Epub 2016 Feb 12.

Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Sorbonne Universités, UPMC Univ Paris 06, UMR 7211, 75005, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13317-016-0074-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751097PMC
December 2016

Low-Dose IL-2 Induces Regulatory T Cell-Mediated Control of Experimental Food Allergy.

J Immunol 2016 07 3;197(1):188-98. Epub 2016 Jun 3.

Sorbonne Universités, Université Pierre et Marie Curie, Université Paris 6, UMRS 959, I, F-75013 Paris, France; INSERM, UMRS 959, I, F-75013 Paris, France; and Service de Biothérapies et Centre d'Investigation Clinique en Biothérapie, Groupe Hospitalier Pitié Salpêtrière, Assistance Publique - Hôpitaux de Paris, 75013 Paris, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1501271DOI Listing
July 2016

Molecular signatures of neural connectivity in the olfactory cortex.

Nat Commun 2016 07 18;7:12238. Epub 2016 Jul 18.

Center for Interdisciplinary Research in Biology (CIRB), Collège de France, and CNRS, UMR 7241 and INSERM U1050, F-75005 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms12238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960301PMC
July 2016

Treatment of Uveitis by In Situ Administration of Ex Vivo-Activated Polyclonal Regulatory T Cells.

J Immunol 2016 Mar 29;196(5):2109-18. Epub 2016 Jan 29.

Sorbonne Universités, Université Pierre et Marie Curie Univ Paris 06, INSERM, Centre National de la Recherche Scientifique, Centre d'Immunologie et des Maladies Infectieuses (Cimi-Paris), Laboratoire I3, F-75013 Paris, France;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1501723DOI Listing
March 2016

Early Transcriptome Signatures from Immunized Mouse Dendritic Cells Predict Late Vaccine-Induced T-Cell Responses.

PLoS Comput Biol 2016 Mar 21;12(3):e1004801. Epub 2016 Mar 21.

Sorbonne Universités, UPMC Univ Paris 06, UMRS 959, Immunology, Immunopathology, Immunotherapy, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1004801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801398PMC
March 2016

Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 Expression.

J Immunol 2016 Jan 25;196(1):168-81. Epub 2015 Nov 25.

UMR_S 1155 and Département Inflammation-Immunopathologie-Biothérapie, Université Pierre et Marie Curie Paris 06, Sorbonne Universités, F-75020 Paris, France; UMR_S 1155, INSERM, F-75020 Paris, France; Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, F-75020 Paris, France;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1500749DOI Listing
January 2016

Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.

J Immunol 2016 Jan 7;196(2):678-90. Epub 2015 Dec 7.

Sorbonne Universités, Université Pierre et Marie Curie, Université Paris 06, Laboratoire I3 (Immunologie-Immunopathologie-Immunothérapie), F-75013 Paris, France; INSERM, UMR_S 959, F-75013 Paris, France; CNRS, FRE3632, F-75013 Paris, France; and Assistance-Publique Hopitaux de Paris, Groupe Hospitalier Pitié-Salpêtrière, Département de Biothérapies et Centre d'Investigation Clinique en Biothérapie, F-75013 Paris, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1501834DOI Listing
January 2016

Selective IL-2 responsiveness of regulatory T cells through multiple intrinsic mechanisms supports the use of low-dose IL-2 therapy in type 1 diabetes.

Diabetes 2015 Jun 9;64(6):2172-83. Epub 2015 Jan 9.

Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL Diabetes Research Institute, Miller School of Medicine, University of Miami, Miami, FL

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db14-1322DOI Listing
June 2015

TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice.

Eur J Immunol 2015 May 7;45(5):1524-34. Epub 2015 Apr 7.

Sorbonne Universités, UPMC Univ Paris 06, UMRS 959, Immunology-Immunopathology-Immunotherapy (i3), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201445269DOI Listing
May 2015

The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases.

Nat Rev Immunol 2015 May 17;15(5):283-94. Epub 2015 Apr 17.

Department of Pathology, University of California San Francisco, California 94143-0511, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nri3823DOI Listing
May 2015

Down-regulation of CD81 in human cells producing HCV-E1/E2 retroVLPs.

BMC Proc 2011 22;5 Suppl 8:P72. Epub 2011 Nov 22.

Instituto de Biologia Experimental e Tecnológica/Instituto de Tecnologia Química e Biológica (IBET/ITQB-UNL), Apartado 12, P-2781-901 Oeiras, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1753-6561-5-S8-P72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284910PMC
April 2015

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.

J Autoimmun 2015 Apr 26;58:48-58. Epub 2015 Jan 26.

AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (I2B), F-75651, Paris, France; Sorbonne Université, UPMC Univ Paris 06, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), F-75005, Paris, France; Inserm, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), F-75005, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2015.01.001DOI Listing
April 2015

Human and Mouse CD8(+)CD25(+)FOXP3(+) Regulatory T Cells at Steady State and during Interleukin-2 Therapy.

Front Immunol 2015 15;6:171. Epub 2015 Apr 15.

Department of Inflammation-Immunopathology-Biotherapy (I2B), Clinical Investigation Center for Biotherapies (CIC-BTi), Hôpital Pitié-Salpêtrière, Assistance Publique Hôpitaux de Paris (AP-HP) , Paris , France ; UMRS 959, Immunology-Immunopathology-Immunotherapy (I3), Sorbonne Université, Université Pierre-et-Marie-Curie, Institut national de la santé et de la recherche médicale (INSERM) , Paris , France ; FRE 3632, Immunology-Immunopathology-Immunotherapy (I3), Centre national de la recherche scientifique (CNRS) , Paris , France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2015.00171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397865PMC
April 2015

Th1 response and systemic treg deficiency in inclusion body myositis.

PLoS One 2014 4;9(3):e88788. Epub 2014 Mar 4.

Inflammation-Immunopathology-Biotherapy (i2B), Hôpital Pitié-Salpêtrière, Assistance Publique - Hôpitaux de Paris, Paris, France; Internal Medicine Department 1, Centre de référence Maladie Neuromusculaire, Assistance Publique - Hôpitaux de Paris, Hôpital Pitié-Salpêtrière Paris, France; U974, Sorbonne Universités, Pierre and Marie Curie University, Paris 06, Paris, France; U974, Institut National de la Santé et de la Recherche Médicale, Paris, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088788PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942319PMC
February 2015

Interleukin 2 in the pathogenesis and therapy of type 1 diabetes.

Curr Diab Rep 2014 Dec;14(12):553

Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), AP-HP, Hôpital Pitié-Salpêtrière, 83 Boulevard de l'Hôpital, 75651, Paris, France,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11892-014-0553-6DOI Listing
December 2014

Regulatory T-cells in pregnancy: historical perspective, state of the art, and burning questions.

Front Immunol 2014 21;5:389. Epub 2014 Aug 21.

Sorbonne Université, UPMC Univ Paris 06, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3) , Paris , France ; INSERM, UMRS 959, Immunology-Immunopathology-Immunotherapy (I3) , Paris , France ; AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B) , Paris , France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2014.00389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139600PMC
September 2014

Beneficial role of rapamycin in experimental autoimmune myositis.

PLoS One 2013 12;8(11):e74450. Epub 2013 Nov 12.

UPMC Univ Paris 06, UMR 7211, Immunology-Immunopathology-Immunotherapy (I3); F-75005, Paris, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074450PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827074PMC
July 2014

Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer.

Clin Immunol 2014 Apr 19;151(2):114-26. Epub 2014 Feb 19.

UPMC Université Paris 06, Sorbonne Universités, UMR 7211, Immunology-Immunopathology-Immunotherapy (I3), F-75005 Paris, France; CNRS, UMR 7211, Immunology-Immunopathology-Immunotherapy (I3), F-75005 Paris, France; INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (I3), F-75005 Paris, France; AP-HP, Pitié-Salpêtrière hospital, Clinical Investigation Center in Biotherapy, F-75651 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clim.2014.02.003DOI Listing
April 2014

Serum biomarker signature identifies patients with B-cell non-Hodgkin lymphoma associated with cryoglobulinemia vasculitis in chronic HCV infection.

Autoimmun Rev 2014 Mar 9;13(3):319-26. Epub 2013 Nov 9.

Département Hospitalo-Universitaire (I2B), UPMC Univ Paris 6, UMR 7211, F-75013 Paris, France; CNRS Centre National de la Recherche Scientifique, UMR 7211, F-75013 Paris, France; INSERM, UMRS959, F-75013 Paris, France; Department of Internal Medicine, Groupe Hospitalier Pitié-Salpétrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris 6, F-75013 Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.autrev.2013.11.001DOI Listing
March 2014

Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial.

Lancet Diabetes Endocrinol 2013 Dec 8;1(4):295-305. Epub 2013 Oct 8.

Clinical Investigation Center for Biotherapies and Inflammation-Immunopathology-Biotherapy Department AP-HP, Hôpital Pitié-Salpêtrière, Paris, France; Immunology-Immunopathology-Immunotherapy UPMC Univ Paris 06, Paris, France; INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy, Paris, France; CNRS, UMR 7211, Immunology-Immunopathology-Immunotherapy, Paris, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-8587(13)70113-XDOI Listing
December 2013

Virus-like particle-based vaccines against hepatitis C virus infection.

Expert Rev Vaccines 2013 Feb;12(2):143-54

UPMC Univ Paris 06, UMR7211, I3, F-75013, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/erv.13.10DOI Listing
February 2013

Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR NK cell levels correlate with disease outcome.

Oncoimmunology 2013 Feb;2(2):e23080

Institut de Cancérologie Gustave Roussy; Villejuif, France ; Centre d'Investigation Clinique Biothérapie CICBT 507; Institut de Cancérologie Gustave Roussy; Villejuif, France ; Unité de Thérapie Cellulaire; Institut de Cancérologie Gustave Roussy; Villejuif, France ; Institut National de la Santé et de la Recherche Médicale; U1015; Institut de Cancérologie Gustave Roussy; Villejuif, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/onci.23080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601178PMC
February 2013

State-transition diagrams for biologists.

PLoS One 2012 23;7(7):e41165. Epub 2012 Jul 23.

Universite Libre de Bruxelles, Brussels, Belgium.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041165PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402529PMC
November 2012

Interleukin 21 correlates with T cell and B cell subset alterations in systemic lupus erythematosus.

J Rheumatol 2012 Sep 1;39(9):1819-28. Epub 2012 Aug 1.

UPMC Université Paris, CNRS, UMR 7211, INSERM, UMRS959, and Department of Internal Medicine, Groupe Hospitalier Pitié-Salpétrière, 47 boulevard de l'Hôpital, 75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.120468DOI Listing
September 2012

GeVaDSs - decision support system for novel Genetic Vaccine development process.

BMC Bioinformatics 2012 May 10;13:91. Epub 2012 May 10.

Institute of Computing Science, Poznań University of Technology, 60-965 Poznań, Poland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-13-91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531312PMC
May 2012

Half of the T-cell repertoire combinatorial diversity is genetically determined in humans and humanized mice.

Eur J Immunol 2012 Mar 20;42(3):760-70. Epub 2011 Dec 20.

Hôpital La Pitié-Salpêtrière, UPMC Univ Paris 06, UMR 7211, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201141798DOI Listing
March 2012

Systems biology in vaccine design.

Microb Biotechnol 2012 Mar 21;5(2):295-304. Epub 2011 Dec 21.

UPMC Univ Paris 06, UMR 7211, F-75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1751-7915.2011.00321.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815789PMC
March 2012

Human CD90 identifies Th17/Tc17 T cell subsets that are depleted in HIV-infected patients.

J Immunol 2012 Feb 19;188(3):981-91. Epub 2011 Dec 19.

Université Pierre et Marie Curie-Université Paris 06, Unité Mixte de Recherche Centre National de la Recherche Scientifique 7211/INSERM 959, 75005 Paris, France.

View Article

Download full-text PDF

Source
http://www.jimmunol.org/content/early/2011/12/19/jimmunol.11
Web Search
http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1101592
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1101592DOI Listing
February 2012

Expansion of functionally anergic CD21-/low marginal zone-like B cell clones in hepatitis C virus infection-related autoimmunity.

J Immunol 2011 Dec 14;187(12):6550-63. Epub 2011 Nov 14.

Laboratoire I3 Immunologie, Immunopathologie, Immunothérapeutique, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7211 et INSERM U959, Groupe Hospitalier Pitié-Salpétrière, Université Pierre et Marie Curie, F-75013 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1102022DOI Listing
December 2011

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis.

N Engl J Med 2011 Dec;365(22):2067-77

Université Pierre et Marie Curie Université Paris 06, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1105143DOI Listing
December 2011

[Immunotherapy of cancer: light at the end of the tunnel?].

Med Sci (Paris) 2011 Oct 21;27(10):795-7. Epub 2011 Oct 21.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/20112710001DOI Listing
October 2011

Critical role of IL-21 in modulating TH17 and regulatory T cells in Behçet disease.

J Allergy Clin Immunol 2011 Sep 2;128(3):655-64. Epub 2011 Jul 2.

Laboratory I3 Immunology, Immunopathology, Immunotherapy, Groupe Hospitalier Pitié-Salpetrière, Université Pierre et Marie Curie, Paris, France.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00916749110085
Publisher Site
http://dx.doi.org/10.1016/j.jaci.2011.05.029DOI Listing
September 2011

Interleukin-25: a cytokine linking eosinophils and adaptive immunity in Churg-Strauss syndrome.

Blood 2010 Nov 20;116(22):4523-31. Epub 2010 Aug 20.

Laboratory I3, Immunology, Immunopathology, Immunotherapy, Unité Mixte de Recherche 7211, Centre National de la Recherche Scientifique/Université Pierre et Marie Curie, Institut National de la Santé et de la Recherche Médicale U959, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2010-02-267542DOI Listing
November 2010

Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles.

Biomaterials 2010 Jul 23;31(19):5237-45. Epub 2010 Mar 23.

Centre de Biophysique Moléculaire, CNRS UPR4301, Université d'Orléans and Inserm, rue Charles Sadron, 45071 Orléans Cedex 2, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biomaterials.2010.02.077DOI Listing
July 2010

High diversity of the immune repertoire in humanized NOD.SCID.gamma c-/- mice.

Eur J Immunol 2009 Aug;39(8):2136-45

Université Pierre et Marie Curie - Paris 6, Centre National de la Recherche Scientifique UMR 7211, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.200939480DOI Listing
August 2009