David Karasik, PhD - Bar Ilan University - Assoc. Prof.

David Karasik

PhD

Bar Ilan University

Assoc. Prof.

Boston, MA | United States

David Karasik, PhD - Bar Ilan University - Assoc. Prof.

David Karasik

PhD

Introduction

Primary Affiliation: Bar Ilan University - Boston, MA , United States

Education

Feb 2018
Tel Aviv University
PhD

Experience

Feb 2018
Medical Faculty
Assoc.Prof.
Anatomy Program chair

Publications

82Publications

3424Reads

1Profile Views

3014PubMed Central Citations

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

Am J Hum Genet 2018 01;102(1):88-102

Department of Internal Medicine, Erasmus MC, 3000 CA Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC, 3000 CA Rotterdam, the Netherlands; Department of Epidemiology, Erasmus MC, 3000 CA Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777980PMC
January 2018
80 Reads
2 Citations
10.931 Impact Factor

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Authors:
Xia Jiang Paul F O'Reilly Hugues Aschard Yi-Hsiang Hsu J Brent Richards Josée Dupuis Erik Ingelsson David Karasik Stefan Pilz Diane Berry Bryan Kestenbaum Jusheng Zheng Jianan Luan Eleni Sofianopoulou Elizabeth A Streeten Demetrius Albanes Pamela L Lutsey Lu Yao Weihong Tang Michael J Econs Henri Wallaschofski Henry Völzke Ang Zhou Chris Power Mark I McCarthy Erin D Michos Eric Boerwinkle Stephanie J Weinstein Neal D Freedman Wen-Yi Huang Natasja M Van Schoor Nathalie van der Velde Lisette C P G M de Groot Anke Enneman L Adrienne Cupples Sarah L Booth Ramachandran S Vasan Ching-Ti Liu Yanhua Zhou Samuli Ripatti Claes Ohlsson Liesbeth Vandenput Mattias Lorentzon Johan G Eriksson M Kyla Shea Denise K Houston Stephen B Kritchevsky Yongmei Liu Kurt K Lohman Luigi Ferrucci Munro Peacock Christian Gieger Marian Beekman Eline Slagboom Joris Deelen Diana van Heemst Marcus E Kleber Winfried März Ian H de Boer Alexis C Wood Jerome I Rotter Stephen S Rich Cassianne Robinson-Cohen Martin den Heijer Marjo-Riitta Jarvelin Alana Cavadino Peter K Joshi James F Wilson Caroline Hayward Lars Lind Karl Michaëlsson Stella Trompet M Carola Zillikens Andre G Uitterlinden Fernando Rivadeneira Linda Broer Lina Zgaga Harry Campbell Evropi Theodoratou Susan M Farrington Maria Timofeeva Malcolm G Dunlop Ana M Valdes Emmi Tikkanen Terho Lehtimäki Leo-Pekka Lyytikäinen Mika Kähönen Olli T Raitakari Vera Mikkilä M Arfan Ikram Naveed Sattar J Wouter Jukema Nicholas J Wareham Claudia Langenberg Nita G Forouhi Thomas E Gundersen Kay-Tee Khaw Adam S Butterworth John Danesh Timothy Spector Thomas J Wang Elina Hyppönen Peter Kraft Douglas P Kiel

Nat Commun 2018 01 17;9(1):260. Epub 2018 Jan 17.

Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-02662-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772647PMC
January 2018
100 Reads
9 Citations
10.742 Impact Factor

Novel therapeutic intervention for osteoporosis prepared with strontium hydroxyapatite and zoledronic acid: In vitro and pharmacodynamic evaluation.

Mater Sci Eng C Mater Biol Appl 2017 Feb 26;71:698-708. Epub 2016 Oct 26.

Department of Pharmacology, Al-Ameen College of Pharmacy, Bangalore, India.

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http://dx.doi.org/10.1016/j.msec.2016.10.066DOI Listing
February 2017
34 Reads
4 Citations
3.090 Impact Factor

The complex genetics of gait speed: genome-wide meta-analysis approach.

Aging (Albany NY) 2017 01;9(1):209-246

Department of Medicine and Genetics Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.18632/aging.101151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310665PMC
January 2017
81 Reads
3 Citations
6.432 Impact Factor

Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families.

J Bone Miner Res 2017 01 26;32(1):106-114. Epub 2016 Oct 26.

Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.

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http://dx.doi.org/10.1002/jbmr.2915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310688PMC
January 2017
21 Reads
1 Citation
6.832 Impact Factor

A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples.

Sci Rep 2016 12 22;6:39313. Epub 2016 Dec 22.

Institute for Aging Research, Hebrew SeniorLife, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/srep39313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177868PMC
December 2016
62 Reads
3 Citations
5.080 Impact Factor

Leukocyte telomere length pattern in a Chuvash population that experienced mass famine in 1922-1923: a retrospective cohort study.

Am J Clin Nutr 2016 11 12;104(5):1410-1415. Epub 2016 Oct 12.

Faculty of Medicine in the Galilee, Bar Ilan University, Safed, Israel.

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http://dx.doi.org/10.3945/ajcn.116.138040DOI Listing
November 2016
21 Reads
1 Citation
6.770 Impact Factor

The genetics of bone mass and susceptibility to bone diseases.

Nat Rev Rheumatol 2016 07;12(8):496

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http://dx.doi.org/10.1038/nrrheum.2016.118DOI Listing
July 2016
3 Reads
4 Citations
9.850 Impact Factor

The genetics of bone mass and susceptibility to bone diseases.

Nat Rev Rheumatol 2016 Jun 7;12(6):323-34. Epub 2016 Apr 7.

Department of Oral and Craniofacial Sciences, University of Missouri-Kansas City School of Dentistry, 650 East 25th Street, Kansas City, Missouri 64108, USA.

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http://dx.doi.org/10.1038/nrrheum.2016.48DOI Listing
June 2016
5 Reads
10 Citations
9.850 Impact Factor

FABP4 is a leading candidate gene associated with residual feed intake in growing Holstein calves.

Physiol Genomics 2016 05 18;48(5):367-76. Epub 2016 Mar 18.

Beef cattle section, Newe-Ya'ar Research Center, Agricultural Research Organization, Ramat Yishay, Israel;

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http://dx.doi.org/10.1152/physiolgenomics.00121.2015DOI Listing
May 2016
1 Read
1 Citation
2.374 Impact Factor

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche.

Nat Commun 2015 Dec 17;6:10257. Epub 2015 Dec 17.

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http://dx.doi.org/10.1038/ncomms10257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703878PMC
December 2015
62 Reads
10.742 Impact Factor

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Authors:
Felix R Day Katherine S Ruth Deborah J Thompson Kathryn L Lunetta Natalia Pervjakova Daniel I Chasman Lisette Stolk Hilary K Finucane Patrick Sulem Brendan Bulik-Sullivan Tõnu Esko Andrew D Johnson Cathy E Elks Nora Franceschini Chunyan He Elisabeth Altmaier Jennifer A Brody Lude L Franke Jennifer E Huffman Margaux F Keller Patrick F McArdle Teresa Nutile Eleonora Porcu Antonietta Robino Lynda M Rose Ursula M Schick Jennifer A Smith Alexander Teumer Michela Traglia Dragana Vuckovic Jie Yao Wei Zhao Eva Albrecht Najaf Amin Tanguy Corre Jouke-Jan Hottenga Massimo Mangino Albert V Smith Toshiko Tanaka Goncalo Abecasis Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Volker Arndt Alice M Arnold Caterina Barbieri Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Leslie Bernstein Suzette J Bielinski Carl Blomqvist Eric Boerwinkle Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Anne-Lise Borresen-Dale Thibaud S Boutin Hiltrud Brauch Hermann Brenner Thomas Brüning Barbara Burwinkel Archie Campbell Harry Campbell Stephen J Chanock J Ross Chapman Yii-Der Ida Chen Georgia Chenevix-Trench Fergus J Couch Andrea D Coviello Angela Cox Kamila Czene Hatef Darabi Immaculata De Vivo Ellen W Demerath Joe Dennis Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Alison M Dunning John D Eicher Peter A Fasching Jessica D Faul Jonine Figueroa Dieter Flesch-Janys Ilaria Gandin Melissa E Garcia Montserrat García-Closas Graham G Giles Giorgia G Girotto Mark S Goldberg Anna González-Neira Mark O Goodarzi Megan L Grove Daniel F Gudbjartsson Pascal Guénel Xiuqing Guo Christopher A Haiman Per Hall Ute Hamann Brian E Henderson Lynne J Hocking Albert Hofman Georg Homuth Maartje J Hooning John L Hopper Frank B Hu Jinyan Huang Keith Humphreys David J Hunter Anna Jakubowska Samuel E Jones Maria Kabisch David Karasik Julia A Knight Ivana Kolcic Charles Kooperberg Veli-Matti Kosma Jennifer Kriebel Vessela Kristensen Diether Lambrechts Claudia Langenberg Jingmei Li Xin Li Sara Lindström Yongmei Liu Jian'an Luan Jan Lubinski Reedik Mägi Arto Mannermaa Judith Manz Sara Margolin Jonathan Marten Nicholas G Martin Corrado Masciullo Alfons Meindl Kyriaki Michailidou Evelin Mihailov Lili Milani Roger L Milne Martina Müller-Nurasyid Michael Nalls Ben M Neale Heli Nevanlinna Patrick Neven Anne B Newman Børge G Nordestgaard Janet E Olson Sandosh Padmanabhan Paolo Peterlongo Ulrike Peters Astrid Petersmann Julian Peto Paul D P Pharoah Nicola N Pirastu Ailith Pirie Giorgio Pistis Ozren Polasek David Porteous Bruce M Psaty Katri Pylkäs Paolo Radice Leslie J Raffel Fernando Rivadeneira Igor Rudan Anja Rudolph Daniela Ruggiero Cinzia F Sala Serena Sanna Elinor J Sawyer David Schlessinger Marjanka K Schmidt Frank Schmidt Rita K Schmutzler Minouk J Schoemaker Robert A Scott Caroline M Seynaeve Jacques Simard Rossella Sorice Melissa C Southey Doris Stöckl Konstantin Strauch Anthony Swerdlow Kent D Taylor Unnur Thorsteinsdottir Amanda E Toland Ian Tomlinson Thérèse Truong Laufey Tryggvadottir Stephen T Turner Diego Vozzi Qin Wang Melissa Wellons Gonneke Willemsen James F Wilson Robert Winqvist Bruce B H R Wolffenbuttel Alan F Wright Drakoulis Yannoukakos Tatijana Zemunik Wei Zheng Marek Zygmunt Sven Bergmann Dorret I Boomsma Julie E Buring Luigi Ferrucci Grant W Montgomery Vilmundur Gudnason Tim D Spector Cornelia M van Duijn Behrooz Z Alizadeh Marina Ciullo Laura Crisponi Douglas F Easton Paolo P Gasparini Christian Gieger Tamara B Harris Caroline Hayward Sharon L R Kardia Peter Kraft Barbara McKnight Andres Metspalu Alanna C Morrison Alex P Reiner Paul M Ridker Jerome I Rotter Daniela Toniolo André G Uitterlinden Sheila Ulivi Henry Völzke Nicholas J Wareham David R Weir Laura M Yerges-Armstrong Alkes L Price Kari Stefansson Jenny A Visser Ken K Ong Jenny Chang-Claude Joanne M Murabito John R B Perry Anna Murray

Nat Genet 2015 Nov 28;47(11):1294-1303. Epub 2015 Sep 28.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.

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http://dx.doi.org/10.1038/ng.3412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661791PMC
November 2015
134 Reads
46 Citations
29.352 Impact Factor

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://dx.doi.org/10.1038/nature14878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015
105 Reads
77 Citations
42.351 Impact Factor

Models to explore genetics of human aging.

Adv Exp Med Biol 2015 ;847:141-61

Hebrew Senior Life Institute for Aging Research, 1200 Centre Street, 02131, Boston, MA, USA,

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http://dx.doi.org/10.1007/978-1-4939-2404-2_7DOI Listing
August 2015
7 Reads
2 Citations

Rare coding variants and X-linked loci associated with age at menarche.

Nat Commun 2015 Aug 4;6:7756. Epub 2015 Aug 4.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ncomms8756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538850PMC
August 2015
106 Reads
12 Citations
10.742 Impact Factor

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

Authors:
John Rb Perry Felix Day Cathy E Elks Patrick Sulem Deborah J Thompson Teresa Ferreira Chunyan He Daniel I Chasman Tõnu Esko Gudmar Thorleifsson Eva Albrecht Wei Q Ang Tanguy Corre Diana L Cousminer Bjarke Feenstra Nora Franceschini Andrea Ganna Andrew D Johnson Sanela Kjellqvist Kathryn L Lunetta George McMahon Ilja M Nolte Lavinia Paternoster Eleonora Porcu Albert V Smith Lisette Stolk Alexander Teumer Natalia Tšernikova Emmi Tikkanen Sheila Ulivi Erin K Wagner Najaf Amin Laura J Bierut Enda M Byrne Jouke-Jan Hottenga Daniel L Koller Massimo Mangino Tune H Pers Laura M Yerges-Armstrong Jing Hua Zhao Irene L Andrulis Hoda Anton-Culver Femke Atsma Stefania Bandinelli Matthias W Beckmann Javier Benitez Carl Blomqvist Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Hiltrud Brauch Hermann Brenner Julie E Buring Jenny Chang-Claude Stephen Chanock Jinhui Chen Georgia Chenevix-Trench J Margriet Collée Fergus J Couch David Couper Andrea D Coveillo Angela Cox Kamila Czene Adamo Pio D'adamo George Davey Smith Immaculata De Vivo Ellen W Demerath Joe Dennis Peter Devilee Aida K Dieffenbach Alison M Dunning Gudny Eiriksdottir Johan G Eriksson Peter A Fasching Luigi Ferrucci Dieter Flesch-Janys Henrik Flyger Tatiana Foroud Lude Franke Melissa E Garcia Montserrat García-Closas Frank Geller Eco Ej de Geus Graham G Giles Daniel F Gudbjartsson Vilmundur Gudnason Pascal Guénel Suiqun Guo Per Hall Ute Hamann Robin Haring Catharina A Hartman Andrew C Heath Albert Hofman Maartje J Hooning John L Hopper Frank B Hu David J Hunter David Karasik Douglas P Kiel Julia A Knight Veli-Matti Kosma Zoltan Kutalik Sandra Lai Diether Lambrechts Annika Lindblom Reedik Mägi Patrik K Magnusson Arto Mannermaa Nicholas G Martin Gisli Masson Patrick F McArdle Wendy L McArdle Mads Melbye Kyriaki Michailidou Evelin Mihailov Lili Milani Roger L Milne Heli Nevanlinna Patrick Neven Ellen A Nohr Albertine J Oldehinkel Ben A Oostra Aarno Palotie Munro Peacock Nancy L Pedersen Paolo Peterlongo Julian Peto Paul Dp Pharoah Dirkje S Postma Anneli Pouta Katri Pylkäs Paolo Radice Susan Ring Fernando Rivadeneira Antonietta Robino Lynda M Rose Anja Rudolph Veikko Salomaa Serena Sanna David Schlessinger Marjanka K Schmidt Mellissa C Southey Ulla Sovio Meir J Stampfer Doris Stöckl Anna M Storniolo Nicholas J Timpson Jonathan Tyrer Jenny A Visser Peter Vollenweider Henry Völzke Gerard Waeber Melanie Waldenberger Henri Wallaschofski Qin Wang Gonneke Willemsen Robert Winqvist Bruce Hr Wolffenbuttel Margaret J Wright Dorret I Boomsma Michael J Econs Kay-Tee Khaw Ruth Jf Loos Mark I McCarthy Grant W Montgomery John P Rice Elizabeth A Streeten Unnur Thorsteinsdottir Cornelia M van Duijn Behrooz Z Alizadeh Sven Bergmann Eric Boerwinkle Heather A Boyd Laura Crisponi Paolo Gasparini Christian Gieger Tamara B Harris Erik Ingelsson Marjo-Riitta Järvelin Peter Kraft Debbie Lawlor Andres Metspalu Craig E Pennell Paul M Ridker Harold Snieder Thorkild Ia Sørensen Tim D Spector David P Strachan André G Uitterlinden Nicholas J Wareham Elisabeth Widen Marek Zygmunt Anna Murray Douglas F Easton Kari Stefansson Joanne M Murabito Ken K Ong

Nature 2014 Oct 23;514(7520):92-97. Epub 2014 Jul 23.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.1038/nature13545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185210PMC
October 2014
136 Reads
113 Citations
42.351 Impact Factor

METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-κB signaling pathway.

J Bone Miner Res 2014 Jul;29(7):1531-1540

Institute for Aging Research, Hebrew SeniorLife, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1002/jbmr.2200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074268PMC
July 2014
25 Reads
13 Citations
6.832 Impact Factor

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.

Authors:
Alireza Moayyeri Yi-Hsiang Hsu David Karasik Karol Estrada Su-Mei Xiao Carrie Nielson Priya Srikanth Sylvie Giroux Scott G Wilson Hou-Feng Zheng Albert V Smith Stephen R Pye Paul J Leo Alexander Teumer Joo-Yeon Hwang Claes Ohlsson Fiona McGuigan Ryan L Minster Caroline Hayward José M Olmos Leo-Pekka Lyytikäinen Joshua R Lewis Karin M A Swart Laura Masi Chris Oldmeadow Elizabeth G Holliday Sulin Cheng Natasja M van Schoor Nicholas C Harvey Marcin Kruk Fabiola del Greco M Wilmar Igl Olivia Trummer Efi Grigoriou Robert Luben Ching-Ti Liu Yanhua Zhou Ling Oei Carolina Medina-Gomez Joseph Zmuda Greg Tranah Suzanne J Brown Frances M Williams Nicole Soranzo Johanna Jakobsdottir Kristin Siggeirsdottir Kate L Holliday Anke Hannemann Min Jin Go Melissa Garcia Ozren Polasek Marika Laaksonen Kun Zhu Anke W Enneman Mark McEvoy Roseanne Peel Pak Chung Sham Maciej Jaworski Åsa Johansson Andrew A Hicks Pawel Pludowski Rodney Scott Rosalie A M Dhonukshe-Rutten Nathalie van der Velde Mika Kähönen Jorma S Viikari Harri Sievänen Olli T Raitakari Jesús González-Macías Jose L Hernández Dan Mellström Osten Ljunggren Yoon Shin Cho Uwe Völker Matthias Nauck Georg Homuth Henry Völzke Robin Haring Matthew A Brown Eugene McCloskey Geoffrey C Nicholson Richard Eastell John A Eisman Graeme Jones Ian R Reid Elaine M Dennison John Wark Steven Boonen Dirk Vanderschueren Frederick C W Wu Thor Aspelund J Brent Richards Doug Bauer Albert Hofman Kay-Tee Khaw George Dedoussis Barbara Obermayer-Pietsch Ulf Gyllensten Peter P Pramstaller Roman S Lorenc Cyrus Cooper Annie Wai Chee Kung Paul Lips Markku Alen John Attia Maria Luisa Brandi Lisette C P G M de Groot Terho Lehtimäki José A Riancho Harry Campbell Yongmei Liu Tamara B Harris Kristina Akesson Magnus Karlsson Jong-Young Lee Henri Wallaschofski Emma L Duncan Terence W O'Neill Vilmundur Gudnason Timothy D Spector François Rousseau Eric Orwoll Steven R Cummings Nick J Wareham Fernando Rivadeneira Andre G Uitterlinden Richard L Prince Douglas P Kiel Jonathan Reeve Stephen K Kaptoge

Hum Mol Genet 2014 Jun 14;23(11):3054-68. Epub 2014 Jan 14.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/ddt675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038791PMC
June 2014
117 Reads
21 Citations
6.393 Impact Factor

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.

Hum Mol Genet 2014 May 19;23(9):2490-7. Epub 2013 Dec 19.

University of Exeter Medical School, Exeter, UK.

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http://dx.doi.org/10.1093/hmg/ddt620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976329PMC
May 2014
72 Reads
13 Citations
6.393 Impact Factor

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

J Med Genet 2014 Feb 16;51(2):122-31. Epub 2013 Dec 16.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://www.molepi.nl/uploads/publicaties/2014/2014_oei_jmedg
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http://jmg.bmj.com/cgi/doi/10.1136/jmedgenet-2013-102064
Publisher Site
http://dx.doi.org/10.1136/jmedgenet-2013-102064DOI Listing
February 2014
156 Reads
11 Citations
6.340 Impact Factor

Impact of the environment on the skeleton: is it modulated by genetic factors?

Curr Osteoporos Rep 2013 Sep;11(3):219-28

The Jackson Laboratory, 600 Main St, Bar Harbor, ME, 04609, USA,

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http://dx.doi.org/10.1007/s11914-013-0151-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038269PMC
September 2013
7 Reads
1 Citation

Structural maintenance of chromosome complexes and bone development: the beginning of a wonderful relationship?

Bonekey Rep 2013 Aug 7;2:388. Epub 2013 Aug 7.

Faculty of Medicine in the Galilee, Bar-Ilan University , Safed, Israel.

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http://dx.doi.org/10.1038/bonekey.2013.122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765053PMC
August 2013
2 Reads
1 Citation

Osteoporosis genetics: year 2011 in review.

Bonekey Rep 2012 1;1:114. Epub 2012 Aug 1.

Faculty of Medicine in the Galilee, Bar-Ilan University , Safed, Israel .

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http://dx.doi.org/10.1038/bonekey.2012.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3727733PMC
August 2013
2 Reads
2 Citations

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.

Authors:
Andrea D Coviello Robin Haring Melissa Wellons Dhananjay Vaidya Terho Lehtimäki Sarah Keildson Kathryn L Lunetta Chunyan He Myriam Fornage Vasiliki Lagou Massimo Mangino N Charlotte Onland-Moret Brian Chen Joel Eriksson Melissa Garcia Yong Mei Liu Annemarie Koster Kurt Lohman Leo-Pekka Lyytikäinen Ann-Kristin Petersen Jennifer Prescott Lisette Stolk Liesbeth Vandenput Andrew R Wood Wei Vivian Zhuang Aimo Ruokonen Anna-Liisa Hartikainen Anneli Pouta Stefania Bandinelli Reiner Biffar Georg Brabant David G Cox Yuhui Chen Steven Cummings Luigi Ferrucci Marc J Gunter Susan E Hankinson Hannu Martikainen Albert Hofman Georg Homuth Thomas Illig John-Olov Jansson Andrew D Johnson David Karasik Magnus Karlsson Johannes Kettunen Douglas P Kiel Peter Kraft Jingmin Liu Östen Ljunggren Mattias Lorentzon Marcello Maggio Marcello R P Markus Dan Mellström Iva Miljkovic Daniel Mirel Sarah Nelson Laure Morin Papunen Petra H M Peeters Inga Prokopenko Leslie Raffel Martin Reincke Alex P Reiner Kathryn Rexrode Fernando Rivadeneira Stephen M Schwartz David Siscovick Nicole Soranzo Doris Stöckl Shelley Tworoger André G Uitterlinden Carla H van Gils Ramachandran S Vasan H-Erich Wichmann Guangju Zhai Shalender Bhasin Martin Bidlingmaier Stephen J Chanock Immaculata De Vivo Tamara B Harris David J Hunter Mika Kähönen Simin Liu Pamela Ouyang Tim D Spector Yvonne T van der Schouw Jorma Viikari Henri Wallaschofski Mark I McCarthy Timothy M Frayling Anna Murray Steve Franks Marjo-Riitta Järvelin Frank H de Jong Olli Raitakari Alexander Teumer Claes Ohlsson Joanne M Murabito John R B Perry

PLoS Genet 2012 19;8(7):e1002805. Epub 2012 Jul 19.

Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400553PMC
January 2013
119 Reads
39 Citations

The genetic pleiotropy of musculoskeletal aging.

Front Physiol 2012 8;3:303. Epub 2012 Aug 8.

Faculty of Medicine in the Galilee, Bar-Ilan University Safed, Israel.

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October 2012
11 Reads
7 Citations

Assessment of gene-by-sex interaction effect on bone mineral density.

J Bone Miner Res 2012 Oct;27(10):2051-64

Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue CT3, Boston,MA 02118, USA.

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October 2012
24 Reads
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6.832 Impact Factor

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Authors:
Karol Estrada Unnur Styrkarsdottir Evangelos Evangelou Yi-Hsiang Hsu Emma L Duncan Evangelia E Ntzani Ling Oei Omar M E Albagha Najaf Amin John P Kemp Daniel L Koller Guo Li Ching-Ti Liu Ryan L Minster Alireza Moayyeri Liesbeth Vandenput Dana Willner Su-Mei Xiao Laura M Yerges-Armstrong Hou-Feng Zheng Nerea Alonso Joel Eriksson Candace M Kammerer Stephen K Kaptoge Paul J Leo Gudmar Thorleifsson Scott G Wilson James F Wilson Ville Aalto Markku Alen Aaron K Aragaki Thor Aspelund Jacqueline R Center Zoe Dailiana David J Duggan Melissa Garcia Natàlia Garcia-Giralt Sylvie Giroux Göran Hallmans Lynne J Hocking Lise Bjerre Husted Karen A Jameson Rita Khusainova Ghi Su Kim Charles Kooperberg Theodora Koromila Marcin Kruk Marika Laaksonen Andrea Z Lacroix Seung Hun Lee Ping C Leung Joshua R Lewis Laura Masi Simona Mencej-Bedrac Tuan V Nguyen Xavier Nogues Millan S Patel Janez Prezelj Lynda M Rose Serena Scollen Kristin Siggeirsdottir Albert V Smith Olle Svensson Stella Trompet Olivia Trummer Natasja M van Schoor Jean Woo Kun Zhu Susana Balcells Maria Luisa Brandi Brendan M Buckley Sulin Cheng Claus Christiansen Cyrus Cooper George Dedoussis Ian Ford Morten Frost David Goltzman Jesús González-Macías Mika Kähönen Magnus Karlsson Elza Khusnutdinova Jung-Min Koh Panagoula Kollia Bente Lomholt Langdahl William D Leslie Paul Lips Östen Ljunggren Roman S Lorenc Janja Marc Dan Mellström Barbara Obermayer-Pietsch José M Olmos Ulrika Pettersson-Kymmer David M Reid José A Riancho Paul M Ridker François Rousseau P Eline Slagboom Nelson L S Tang Roser Urreizti Wim Van Hul Jorma Viikari María T Zarrabeitia Yurii S Aulchenko Martha Castano-Betancourt Elin Grundberg Lizbeth Herrera Thorvaldur Ingvarsson Hrefna Johannsdottir Tony Kwan Rui Li Robert Luben Carolina Medina-Gómez Stefan Th Palsson Sjur Reppe Jerome I Rotter Gunnar Sigurdsson Joyce B J van Meurs Dominique Verlaan Frances M K Williams Andrew R Wood Yanhua Zhou Kaare M Gautvik Tomi Pastinen Soumya Raychaudhuri Jane A Cauley Daniel I Chasman Graeme R Clark Steven R Cummings Patrick Danoy Elaine M Dennison Richard Eastell John A Eisman Vilmundur Gudnason Albert Hofman Rebecca D Jackson Graeme Jones J Wouter Jukema Kay-Tee Khaw Terho Lehtimäki Yongmei Liu Mattias Lorentzon Eugene McCloskey Braxton D Mitchell Kannabiran Nandakumar Geoffrey C Nicholson Ben A Oostra Munro Peacock Huibert A P Pols Richard L Prince Olli Raitakari Ian R Reid John Robbins Philip N Sambrook Pak Chung Sham Alan R Shuldiner Frances A Tylavsky Cornelia M van Duijn Nick J Wareham L Adrienne Cupples Michael J Econs David M Evans Tamara B Harris Annie Wai Chee Kung Bruce M Psaty Jonathan Reeve Timothy D Spector Elizabeth A Streeten M Carola Zillikens Unnur Thorsteinsdottir Claes Ohlsson David Karasik J Brent Richards Matthew A Brown Kari Stefansson André G Uitterlinden Stuart H Ralston John P A Ioannidis Douglas P Kiel Fernando Rivadeneira

Nat Genet 2012 Apr 15;44(5):491-501. Epub 2012 Apr 15.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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April 2012
110 Reads
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29.352 Impact Factor

Genome-wide association of an integrated osteoporosis-related phenotype: is there evidence for pleiotropic genes?

J Bone Miner Res 2012 Feb;27(2):319-30

Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA 02131, USA.

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February 2012
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Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

Authors:
Lisette Stolk John R B Perry Daniel I Chasman Chunyan He Massimo Mangino Patrick Sulem Maja Barbalic Linda Broer Enda M Byrne Florian Ernst Tõnu Esko Nora Franceschini Daniel F Gudbjartsson Jouke-Jan Hottenga Peter Kraft Patrick F McArdle Eleonora Porcu So-Youn Shin Albert V Smith Sophie van Wingerden Guangju Zhai Wei V Zhuang Eva Albrecht Behrooz Z Alizadeh Thor Aspelund Stefania Bandinelli Lovorka Barac Lauc Jacques S Beckmann Mladen Boban Eric Boerwinkle Frank J Broekmans Andrea Burri Harry Campbell Stephen J Chanock Constance Chen Marilyn C Cornelis Tanguy Corre Andrea D Coviello Pio d'Adamo Gail Davies Ulf de Faire Eco J C de Geus Ian J Deary George V Z Dedoussis Panagiotis Deloukas Shah Ebrahim Gudny Eiriksdottir Valur Emilsson Johan G Eriksson Bart C J M Fauser Liana Ferreli Luigi Ferrucci Krista Fischer Aaron R Folsom Melissa E Garcia Paolo Gasparini Christian Gieger Nicole Glazer Diederick E Grobbee Per Hall Toomas Haller Susan E Hankinson Merli Hass Caroline Hayward Andrew C Heath Albert Hofman Erik Ingelsson A Cecile J W Janssens Andrew D Johnson David Karasik Sharon L R Kardia Jules Keyzer Douglas P Kiel Ivana Kolcic Zoltán Kutalik Jari Lahti Sandra Lai Triin Laisk Joop S E Laven Debbie A Lawlor Jianjun Liu Lorna M Lopez Yvonne V Louwers Patrik K E Magnusson Mara Marongiu Nicholas G Martin Irena Martinovic Klaric Corrado Masciullo Barbara McKnight Sarah E Medland David Melzer Vincent Mooser Pau Navarro Anne B Newman Dale R Nyholt N Charlotte Onland-Moret Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Petra H M Peeters Giorgio Pistis Andrew S Plump Ozren Polasek Victor J M Pop Bruce M Psaty Katri Räikkönen Emil Rehnberg Jerome I Rotter Igor Rudan Cinzia Sala Andres Salumets Angelo Scuteri Andrew Singleton Jennifer A Smith Harold Snieder Nicole Soranzo Simon N Stacey John M Starr Maria G Stathopoulou Kathleen Stirrups Ronald P Stolk Unnur Styrkarsdottir Yan V Sun Albert Tenesa Barbara Thorand Daniela Toniolo Laufey Tryggvadottir Kim Tsui Sheila Ulivi Rob M van Dam Yvonne T van der Schouw Carla H van Gils Peter van Nierop Jacqueline M Vink Peter M Visscher Marlies Voorhuis Gérard Waeber Henri Wallaschofski H Erich Wichmann Elisabeth Widen Colette J M Wijnands-van Gent Gonneke Willemsen James F Wilson Bruce H R Wolffenbuttel Alan F Wright Laura M Yerges-Armstrong Tatijana Zemunik Lina Zgaga M Carola Zillikens Marek Zygmunt Alice M Arnold Dorret I Boomsma Julie E Buring Laura Crisponi Ellen W Demerath Vilmundur Gudnason Tamara B Harris Frank B Hu David J Hunter Lenore J Launer Andres Metspalu Grant W Montgomery Ben A Oostra Paul M Ridker Serena Sanna David Schlessinger Tim D Spector Kari Stefansson Elizabeth A Streeten Unnur Thorsteinsdottir Manuela Uda André G Uitterlinden Cornelia M van Duijn Henry Völzke Anna Murray Joanne M Murabito Jenny A Visser Kathryn L Lunetta

Nat Genet 2012 Jan 22;44(3):260-8. Epub 2012 Jan 22.

Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.

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January 2012
120 Reads
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Large common deletions associate with mortality at old age.

Hum Mol Genet 2011 Nov 11;20(21):4290-6. Epub 2011 Aug 11.

Department of Epidemiology, Erasmus Medical Center, Rotterdam, CA 3000, The Netherlands.

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November 2011
29 Reads
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Genetic determinants of serum testosterone concentrations in men.

PLoS Genet 2011 Oct 6;7(10):e1002313. Epub 2011 Oct 6.

Center for Bone and Arthritis Research, Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.

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October 2011
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Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

Authors:
Tuomas O Kilpeläinen M Carola Zillikens Alena Stančákova Francis M Finucane Janina S Ried Claudia Langenberg Weihua Zhang Jacques S Beckmann Jian'an Luan Liesbeth Vandenput Unnur Styrkarsdottir Yanhua Zhou Albert Vernon Smith Jing-Hua Zhao Najaf Amin Sailaja Vedantam So-Youn Shin Talin Haritunians Mao Fu Mary F Feitosa Meena Kumari Bjarni V Halldorsson Emmi Tikkanen Massimo Mangino Caroline Hayward Ci Song Alice M Arnold Yurii S Aulchenko Ben A Oostra Harry Campbell L Adrienne Cupples Kathryn E Davis Angela Döring Gudny Eiriksdottir Karol Estrada José Manuel Fernández-Real Melissa Garcia Christian Gieger Nicole L Glazer Candace Guiducci Albert Hofman Steve E Humphries Bo Isomaa Leonie C Jacobs Antti Jula David Karasik Magnus K Karlsson Kay-Tee Khaw Lauren J Kim Mika Kivimäki Norman Klopp Brigitte Kühnel Johanna Kuusisto Yongmei Liu Osten Ljunggren Mattias Lorentzon Robert N Luben Barbara McKnight Dan Mellström Braxton D Mitchell Vincent Mooser José Maria Moreno Satu Männistö Jeffery R O'Connell Laura Pascoe Leena Peltonen Belén Peral Markus Perola Bruce M Psaty Veikko Salomaa David B Savage Robert K Semple Tatjana Skaric-Juric Gunnar Sigurdsson Kijoung S Song Timothy D Spector Ann-Christine Syvänen Philippa J Talmud Gudmar Thorleifsson Unnur Thorsteinsdottir André G Uitterlinden Cornelia M van Duijn Antonio Vidal-Puig Sarah H Wild Alan F Wright Deborah J Clegg Eric Schadt James F Wilson Igor Rudan Samuli Ripatti Ingrid B Borecki Alan R Shuldiner Erik Ingelsson John-Olov Jansson Robert C Kaplan Vilmundur Gudnason Tamara B Harris Leif Groop Douglas P Kiel Fernando Rivadeneira Mark Walker Inês Barroso Peter Vollenweider Gérard Waeber John C Chambers Jaspal S Kooner Nicole Soranzo Joel N Hirschhorn Kari Stefansson H-Erich Wichmann Claes Ohlsson Stephen O'Rahilly Nicholas J Wareham Elizabeth K Speliotes Caroline S Fox Markku Laakso Ruth J F Loos

Nat Genet 2011 Jun 26;43(8):753-60. Epub 2011 Jun 26.

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262230PMC
June 2011
42 Reads
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29.352 Impact Factor

How pleiotropic genetics of the musculoskeletal system can inform genomics and phenomics of aging.

Authors:
David Karasik

Age (Dordr) 2011 Mar 2;33(1):49-62. Epub 2010 Jul 2.

Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, 1200 Centre Street, Boston, MA 02131, USA.

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March 2011
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Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

Authors:
Cathy E Elks John R B Perry Patrick Sulem Daniel I Chasman Nora Franceschini Chunyan He Kathryn L Lunetta Jenny A Visser Enda M Byrne Diana L Cousminer Daniel F Gudbjartsson Tõnu Esko Bjarke Feenstra Jouke-Jan Hottenga Daniel L Koller Zoltán Kutalik Peng Lin Massimo Mangino Mara Marongiu Patrick F McArdle Albert V Smith Lisette Stolk Sophie H van Wingerden Jing Hua Zhao Eva Albrecht Tanguy Corre Erik Ingelsson Caroline Hayward Patrik K E Magnusson Erin N Smith Shelia Ulivi Nicole M Warrington Lina Zgaga Helen Alavere Najaf Amin Thor Aspelund Stefania Bandinelli Inês Barroso Gerald S Berenson Sven Bergmann Hannah Blackburn Eric Boerwinkle Julie E Buring Fabio Busonero Harry Campbell Stephen J Chanock Wei Chen Marilyn C Cornelis David Couper Andrea D Coviello Pio d'Adamo Ulf de Faire Eco J C de Geus Panos Deloukas Angela Döring George Davey Smith Douglas F Easton Gudny Eiriksdottir Valur Emilsson Johan Eriksson Luigi Ferrucci Aaron R Folsom Tatiana Foroud Melissa Garcia Paolo Gasparini Frank Geller Christian Gieger Vilmundur Gudnason Per Hall Susan E Hankinson Liana Ferreli Andrew C Heath Dena G Hernandez Albert Hofman Frank B Hu Thomas Illig Marjo-Riitta Järvelin Andrew D Johnson David Karasik Kay-Tee Khaw Douglas P Kiel Tuomas O Kilpeläinen Ivana Kolcic Peter Kraft Lenore J Launer Joop S E Laven Shengxu Li Jianjun Liu Daniel Levy Nicholas G Martin Wendy L McArdle Mads Melbye Vincent Mooser Jeffrey C Murray Sarah S Murray Michael A Nalls Pau Navarro Mari Nelis Andrew R Ness Kate Northstone Ben A Oostra Munro Peacock Lyle J Palmer Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Leena Peltonen Craig E Pennell Paul Pharoah Ozren Polasek Andrew S Plump Anneli Pouta Eleonora Porcu Thorunn Rafnar John P Rice Susan M Ring Fernando Rivadeneira Igor Rudan Cinzia Sala Veikko Salomaa Serena Sanna David Schlessinger Nicholas J Schork Angelo Scuteri Ayellet V Segrè Alan R Shuldiner Nicole Soranzo Ulla Sovio Sathanur R Srinivasan David P Strachan Mar-Liis Tammesoo Emmi Tikkanen Daniela Toniolo Kim Tsui Laufey Tryggvadottir Jonathon Tyrer Manuela Uda Rob M van Dam Joyce B J van Meurs Peter Vollenweider Gerard Waeber Nicholas J Wareham Dawn M Waterworth Michael N Weedon H Erich Wichmann Gonneke Willemsen James F Wilson Alan F Wright Lauren Young Guangju Zhai Wei Vivian Zhuang Laura J Bierut Dorret I Boomsma Heather A Boyd Laura Crisponi Ellen W Demerath Cornelia M van Duijn Michael J Econs Tamara B Harris David J Hunter Ruth J F Loos Andres Metspalu Grant W Montgomery Paul M Ridker Tim D Spector Elizabeth A Streeten Kari Stefansson Unnur Thorsteinsdottir André G Uitterlinden Elisabeth Widen Joanne M Murabito Ken K Ong Anna Murray

Nat Genet 2010 Dec;42(12):1077-85

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140055PMC
December 2010
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Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

Lancet 2010 Jul 10;376(9736):180-8. Epub 2010 Jun 10.

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086761PMC
July 2010
102 Reads
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Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.

J Bone Miner Res 2010 Jul;25(7):1555-63

Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA 02131, USA.

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July 2010
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Evidence for pleiotropic factors in genetics of the musculoskeletal system.

Bone 2010 May 10;46(5):1226-37. Epub 2010 Feb 10.

Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA.

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Refined QTLs of osteoporosis-related traits by linkage analysis with genome-wide SNPs: Framingham SHARe.

Bone 2010 Apr 11;46(4):1114-21. Epub 2010 Jan 11.

Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA 02131, USA.

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J Bone Miner Res 2009 Apr;24(4):710-8

Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, Massachusetts, USA.

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A genome wide linkage scan of metacarpal size and geometry in the Framingham Study.

Am J Hum Biol 2008 Nov-Dec;20(6):663-70

Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, Massachusetts 02131, USA.

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January 2009
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Osteoporosis: an evolutionary perspective.

Authors:
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Hum Genet 2008 Nov 10;124(4):349-56. Epub 2008 Sep 10.

Institute for Aging Research, Hebrew SeniorLife and Harvard Medical School, 1200 Centre Street, Boston, MA 02131, USA.

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November 2008
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Genetics of the musculoskeletal system: a pleiotropic approach.

J Bone Miner Res 2008 Jun;23(6):788-802

Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, Massachusetts 02131, USA.

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http://dx.doi.org/10.1359/jbmr.080218DOI Listing
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June 2008
6 Reads
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Increased plasma osteoprotegerin concentrations are associated with indices of bone strength of the hip.

J Clin Endocrinol Metab 2008 May 26;93(5):1789-95. Epub 2008 Feb 26.

Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA 02131, USA.

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May 2008
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Hip structural geometry in old and old-old age: similarities and differences between men and women.

Bone 2007 Oct 15;41(4):722-32. Epub 2007 Jun 15.

Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02120, USA.

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Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA, USA.

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June 2006
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Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures.

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Hebrew Rehabilitation Center for Aged, Research and Training Institute, 1200 Centre Street, Boston, MA 02131, USA.

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Estrogen receptor beta polymorphisms are associated with bone mass in women and men: the Framingham Study.

J Bone Miner Res 2004 May 22;19(5):773-81. Epub 2003 Dec 22.

Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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May 2004
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Interactions of interleukin-6 promoter polymorphisms with dietary and lifestyle factors and their association with bone mass in men and women from the Framingham Osteoporosis Study.

J Bone Miner Res 2004 Apr 5;19(4):552-9. Epub 2004 Jan 5.

Division of Bone Diseases and WHO Collaborating Center for Osteoporosis, Departments of Geriatrics and Internal Medicine, Geneva University Hospital, Geneva, Switzerland.

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April 2004
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Association of a common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene with bone phenotypes depends on plasma folate status.

J Bone Miner Res 2004 Mar 22;19(3):410-8. Epub 2003 Dec 22.

Research and Training Institute, Hebrew Rehabilitation Center for Aged, Boston, Massachusetts 01702, USA.

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March 2004
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Genetic contribution to biological aging: the Framingham Study.

J Gerontol A Biol Sci Med Sci 2004 Mar;59(3):218-26

Hebrew Rehabilitation Center for Aged, and Harvard Medical School, Boston, MA 02131, USA.

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March 2004
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Complex segregation analysis of the radiographic phalanges bone mineral density and their age-related changes.

J Bone Miner Res 2002 Jan;17(1):152-61

Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel.

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January 2002
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Comparative analysis of age prediction by markers of bone change in the hand assessed by roentgenography.

Am J Hum Biol 1999 ;11(1):31-43

Research Unit-Human Population Biology, Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel.

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January 1999
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3 Citations
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Douglas P Kiel

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