David J Lockhart

David J Lockhart

UNVERIFIED PROFILE

Are you David J Lockhart?   Register this Author

Register author
David J Lockhart

David J Lockhart

Publications by authors named "David J Lockhart"

Are you David J Lockhart?   Register this Author

33Publications

1347Reads

27Profile Views

Treatment of Fabry's Disease with the Pharmacologic Chaperone Migalastat.

N Engl J Med 2016 Aug;375(6):545-55

From the Division of Medical Genetics, University of Versailles, Paris-Saclay University, Versailles, and Assistance Publique-Hôpitaux de Paris, Paris - both in France (D.P.G.); the Department of Academic Haematology, Royal Free and University College Medical School, London (D.A.H.), Salford Royal NHS Foundation Trust, Salford (A.J.), and University of Sunderland, Sunderland (S.W.) - all in the United Kingdom; the Department of Nephrology, Royal Melbourne Hospital, Parkville, VIC (K. Nicholls), and the Metabolic Clinic, Women's and Children's Hospital, Adelaide, SA (D.B.) - both in Australia; the Clinical Research Division, Hôpital du Sacré-Coeur, Montreal (D.G.B.); Medical Genetics Service, Clinic Hospital of Porto Alegre, Porto Alegre (R.G.), and Hospital das Clínicas Faculdade de Medicina da Universidade de São Paulo-Ribeirão Preto, Ribeirão Preto (C.M.L.) - both in Brazil; the Departments of Human Genetics (W.R.W., S.P.S.) and Ophthalmology (S.P.S.), Emory University School of Medicine, Atlanta; the Dermatology Unit, University of Parma, Parma, Italy (C.F.); the Faculty of Medicine, Department and Laboratory of Pediatric Metabolic Disorders, Gazi University, Ankara, Turkey (F.E.); the Department of Pediatrics, Hospital Alemán, Buenos Aires (H.A.); the Department of Medical Endocrinology, Rigshospital, Copenhagen University Hospital, Copenhagen (U.F.-R.); Infusion Associates, Grand Rapids, MI (K. Nedd); the Faculty of Medicine, Kasr El Ainy Hospital, Cairo (U.S.E.D.); New York Presbyterian Hospital, New York (M.B.); the Division of Genetics, Ann & Robert H. Lurie Children's Hospital of Chicago, and Northwestern University Feinberg School of Medicine, Chicago (J. Charrow); the Department of Urology, University of Kansas Medical Center, Kansas City (M.D., A.T.); Children's Hospital of Pittsburgh, Pittsburgh (D.F.); Hospital Miguel Servet, Zaragoza (P.G.), and Fundacio Puigvert, Universidad Autónoma de Barcelona, Barcelona (R.T.) - both in Spain; O & O Alpa

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1510198DOI Listing
August 2016

Tuning a three-component reaction for trapping kinase substrate complexes.

J Am Chem Soc 2008 Dec;130(51):17568-74

Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94107, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/ja807066f
Publisher Site
http://dx.doi.org/10.1021/ja807066fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863028PMC
December 2008

Detecting genetic variation in microarray expression data.

Genome Res 2007 Aug 3;17(8):1228-35. Epub 2007 Jul 3.

The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.6307307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1933513PMC
August 2007

Mechanisms of aging in senescence-accelerated mice.

Genome Biol 2005 1;6(6):R48. Epub 2005 Jun 1.

The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gb-2005-6-6-r48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175968PMC
August 2006

Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

Cancer Res 2006 Jan;66(2):1007-14

Departments of Molecular and Cell Biology and Chemistry, Howard Hughes Medical Institute, The University of California at Berkeley, Berkeley, CA 94720, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-05-2788DOI Listing
January 2006

Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice.

Nature 2005 Dec 23;438(7068):662-6. Epub 2005 Oct 23.

The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature04250DOI Listing
December 2005

Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas.

Hum Mol Genet 2005 Sep 8;14(18):2671-84. Epub 2005 Aug 8.

The Salk Institute for Biological Studies, The Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddi301DOI Listing
September 2005

Elevated gene expression levels distinguish human from non-human primate brains.

Proc Natl Acad Sci U S A 2003 Oct 13;100(22):13030-5. Epub 2003 Oct 13.

Laboratory of Genetics, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.2135499100
Publisher Site
http://dx.doi.org/10.1073/pnas.2135499100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC240739PMC
October 2003

DNA arrays and neurobiology--what's new and what's next?

Curr Opin Neurobiol 2002 Oct;12(5):554-61

The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0959-4388(02)00353-7DOI Listing
October 2002

Software and methods for oligonucleotide and cDNA array data analysis.

Genome Biol 2002 23;3(6):SOFTWARE0001. Epub 2002 May 23.

The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139376PMC
http://dx.doi.org/10.1186/gb-2002-3-6-software0001DOI Listing
August 2002

Parallel identification of new genes in Saccharomyces cerevisiae.

Genome Res 2002 Aug;12(8):1210-20

Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.226802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC186640PMC
August 2002