David J Harrison

David J Harrison

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David J Harrison

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The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

Mol Aspects Med 2019 Oct 6;69:48-61. Epub 2019 Aug 6.

Gastrointestinal and Pancreatic Oncology Group, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CIBEREHD, Barcelona, Spain; Unitat de Biologia Cel·lular i Genètica Mèdica, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.07.007DOI Listing
October 2019

Raman spectroscopy investigation of biochemical changes in tumor spheroids with aging and after treatment with staurosporine.

J Biophotonics 2019 May 9;12(5):e201800201. Epub 2019 Jan 9.

School of Chemistry, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1002/jbio.201800201DOI Listing
May 2019

Identifying prognostic structural features in tissue sections of colon cancer patients using point pattern analysis.

Stat Med 2019 Apr 28;38(8):1421-1441. Epub 2018 Nov 28.

School of Arts, Media and Computer Games, Abertay University, UK.

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http://dx.doi.org/10.1002/sim.8046DOI Listing
April 2019

Automated Analysis of Lymphocytic Infiltration, Tumor Budding, and Their Spatial Relationship Improves Prognostic Accuracy in Colorectal Cancer.

Cancer Immunol Res 2019 Apr 7;7(4):609-620. Epub 2019 Mar 7.

Quantitative and Digital Pathology, School of Medicine, University of St. Andrews, St. Andrews, UK.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0377DOI Listing
April 2019

Treatment patterns and patient characteristics among early initiators of PCSK9 inhibitors.

Vasc Health Risk Manag 2018 10;14:409-418. Epub 2018 Dec 10.

Health Economics and Outcomes Research, IQVIA, Plymouth Meeting, PA, USA.

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http://dx.doi.org/10.2147/VHRM.S180496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292243PMC
January 2019

A principled machine learning framework improves accuracy of stage II colorectal cancer prognosis.

NPJ Digit Med 2018 2;1:52. Epub 2018 Oct 2.

2School of Medicine, University of St Andrews, St Andrews, KY16 9TF UK.

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http://dx.doi.org/10.1038/s41746-018-0057-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550189PMC
October 2018

Disease-modifying antirheumatic drug initiation among patients newly diagnosed with rheumatoid arthritis.

Am J Manag Care 2018 07;24(8 Spec No.):SP279-SP285

Truven Health Analytics, an IBM Company, 75 Binney St, Cambridge, MA 02142. Email:

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July 2018

Podocyte injury elicits loss and recovery of cellular forces.

Sci Adv 2018 06 27;4(6):eaap8030. Epub 2018 Jun 27.

School of Medicine, University of St Andrews, St Andrews KY16 9TF, UK.

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http://dx.doi.org/10.1126/sciadv.aap8030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021140PMC
June 2018

The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse.

Cell Transplant 2018 02;27(2):230-244

1 Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, United Kingdom.

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http://dx.doi.org/10.1177/0963689717744788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898691PMC
February 2018

Estimation of Missed Statin Prescription Use in an Administrative Claims Dataset.

J Manag Care Spec Pharm 2017 Sep;23(9):936-942

2 Amgen, Thousand Oaks, California.

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http://dx.doi.org/10.18553/jmcp.2017.23.9.936DOI Listing
September 2017

Epigenetic sampling effects: nephrectomy modifies the clear cell renal cell cancer methylome.

Cell Oncol (Dordr) 2017 Jun 10;40(3):293-297. Epub 2017 Jan 10.

Biobix: Laboratory of Bioinformatics and Computational Genomics, Department of Mathematical Modeling, Statistics and Bioninformatics, Ghent University, Coupure Links 653, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s13402-016-0313-5DOI Listing
June 2017

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.

Oncotarget 2017 Jun;8(26):42857-42875

Cancer Research UK Edinburgh Centre and Division of Pathology Laboratory, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, United Kingdom.

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http://dx.doi.org/10.18632/oncotarget.17143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522111PMC
June 2017

Lickometry: A novel and sensitive method for assessing functional deficits in rats after stroke.

J Cereb Blood Flow Metab 2017 Mar 6;37(3):755-761. Epub 2017 Jan 6.

1 School of Life Sciences, University of Nottingham, UK.

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http://dx.doi.org/10.1177/0271678X16684141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305038PMC
March 2017

Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002.

Eur J Pharm Sci 2017 Jan 8;97:170-181. Epub 2016 Nov 8.

School of Science, Engineering and Technology, University of Abertay, Dundee, UK; School of Arts, Media and Computer Games, University of Abertay, Dundee, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09280987163048
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http://dx.doi.org/10.1016/j.ejps.2016.11.008DOI Listing
January 2017

A novel mechanism of action of HER2 targeted immunotherapy is explained by inhibition of NRF2 function in ovarian cancer cells.

Oncotarget 2016 Nov;7(46):75874-75901

Division of Science, School of Science, Engineering and Technology, Abertay University, Dundee, DD1 1HG, United Kingdom.

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http://dx.doi.org/10.18632/oncotarget.12425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342785PMC
November 2016

Treatment patterns and annual biologic costs in US veterans with rheumatic conditions or psoriasis.

J Med Econ 2016 30;19(1):34-43. Epub 2015 Sep 30.

b b Rheumatology, SLC VA Medical Center and University of Utah , Salt Lake City , UT , USA.

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http://dx.doi.org/10.3111/13696998.2015.1086774DOI Listing
October 2016

Next-Generation Pathology.

Methods Mol Biol 2016 ;1386:61-72

Quantitative and systems pathology, University of St Andrews, North Haugh, Fife, St Andrews, KY16 9TF, UK.

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http://link.springer.com/10.1007/978-1-4939-3283-2_4
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http://dx.doi.org/10.1007/978-1-4939-3283-2_4DOI Listing
October 2016

Could molecular pathology testing in lung cancer be more cost-effective?

J Clin Pathol 2016 Oct 7;69(10):938-41. Epub 2016 Jul 7.

Department of Molecular Pathology, Laboratory Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.

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http://jcp.bmj.com/lookup/doi/10.1136/jclinpath-2016-203811
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http://dx.doi.org/10.1136/jclinpath-2016-203811DOI Listing
October 2016

Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies.

Prostate 2016 09 28;76(12):1078-87. Epub 2016 Apr 28.

Department of Mathematical Modeling, Statistics and Bio-Informatics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1002/pros.23191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111760PMC
September 2016

Total synthesis of dehaloperophoramidine using a highly diastereoselective Hosomi-Sakurai reaction.

Chem Commun (Camb) 2016 Sep 10;52(71):10747-50. Epub 2016 Aug 10.

School of Chemistry and Biomedical Sciences Research Complex, University of St. Andrews and EaStCHEM, St. Andrews, Fife, Scotland KY16 9ST, UK.

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http://dx.doi.org/10.1039/c6cc05747kDOI Listing
September 2016

Novel histopathologic feature identified through image analysis augments stage II colorectal cancer clinical reporting.

Oncotarget 2016 Jul;7(28):44381-44394

Quantitative and Digital Pathology, School of Medicine, University of St Andrews, St Andrews, KY16 9TF, UK.

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http://dx.doi.org/10.18632/oncotarget.10053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190104PMC
July 2016

In Vivo MRI Evidence that Neuropathology is Attenuated by Cognitive Enrichment in the Yac128 Huntington's Disease Mouse Model.

J Huntingtons Dis 2015 ;4(2):149-60

Brain Repair Group, Life Science Building, 3rd Floor, School of Biosciences, Cardiff University, Museum Avenue, Cardiff, UK.

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http://dx.doi.org/10.3233/JHD-150147DOI Listing
June 2016

Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models.

Br J Cancer 2016 Apr 31;114(8):905-16. Epub 2016 Mar 31.

Division of Pathology Laboratories, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1038/bjc.2016.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984802PMC
April 2016

Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models.

BMC Cancer 2016 Mar 10;16:205. Epub 2016 Mar 10.

School of Biology, Sir Harold Mitchell Building, University of St Andrews, St Andrews, Fife, KY16 9TH, UK.

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http://dx.doi.org/10.1186/s12885-016-2212-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787009PMC
March 2016

Sunitinib Treatment Exacerbates Intratumoral Heterogeneity in Metastatic Renal Cancer.

Clin Cancer Res 2015 Sep 26;21(18):4212-23. Epub 2015 May 26.

Renal Cancer Unit, The Royal Free Hospital, London, United Kingdom. Centre for Experimental Cancer Medicine, Bart's Cancer Institute, Queen Mary University of London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0207DOI Listing
September 2015

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system.

Sci Rep 2015 Jun 8;5:10775. Epub 2015 Jun 8.

School of Biology, University of St Andrews, St Andrews, Fife, KY16 9TH, UK.

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http://dx.doi.org/10.1038/srep10775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459080PMC
June 2015

Quantitative analysis of NRF2 pathway reveals key elements of the regulatory circuits underlying antioxidant response and proliferation of ovarian cancer cells.

J Biotechnol 2015 May 5;202:12-30. Epub 2014 Nov 5.

Scottish Informatics, Mathematics, Biology and Statistics Centre (SIMBIOS), University of Abertay Dundee, Dundee DD1 1HG, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01681656140094
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http://dx.doi.org/10.1016/j.jbiotec.2014.09.027DOI Listing
May 2015

Superior mesenteric artery syndrome following sleeve gastrectomy: case report, review of the literature, and video on technique for surgical correction.

Surg Endosc 2015 Apr 13;29(4):992-4. Epub 2014 Aug 13.

Department of Surgery, Cedars-Sinai Medical Center, 8635 W 3rd Street 795 W, Los Angeles, CA, 90048, USA,

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http://link.springer.com/10.1007/s00464-014-3743-z
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http://dx.doi.org/10.1007/s00464-014-3743-zDOI Listing
April 2015

Cost and effectiveness of biologics for rheumatoid arthritis in a commercially insured population.

J Manag Care Spec Pharm 2015 Apr;21(4):318-29

University of Alabama, Faculty Office Tower 820, 510 20th St. South, Birmingham, AL 35294.

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http://dx.doi.org/10.18553/jmcp.2015.21.4.318DOI Listing
April 2015

MBD4 interacts with and recruits USP7 to heterochromatic foci.

J Cell Biochem 2015 Mar;116(3):476-85

MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK; Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang, China.

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http://dx.doi.org/10.1002/jcb.25001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964934PMC
March 2015

The development of prognostic and predictive biomarkers in renal cell cancer are not one and the same thing.

Eur Urol 2015 Jan 11;67(1):21-22. Epub 2014 Aug 11.

Edinburgh Urological Cancer Group, University of Edinburgh, Edinburgh, UK; Scottish Collaboration On Translational Research into Renal Cell Cancer, Scotland, UK.

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http://dx.doi.org/10.1016/j.eururo.2014.07.037DOI Listing
January 2015

Validation of a molecular and pathological model for five-year mortality risk in patients with early stage lung adenocarcinoma.

J Thorac Oncol 2015 Jan;10(1):67-73

*Division of Thoracic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; †Myriad Genetics, Inc., Salt Lake City, UT; ‡Myriad Genetic Laboratories, Inc., Salt Lake City, UT, §Levine Cancer Institute, Charlotte, NC, ‖Istituto Europeo di Oncologia, Milan, Italy; ¶Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX; #Royal Infirmary of Edinburgh, Edinburgh, Scotland; and **School of Medicine, University of St. Andrews, St. Andrews, Scotland.

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http://dx.doi.org/10.1097/JTO.0000000000000365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272230PMC
January 2015

Increased STAT1 signaling in endocrine-resistant breast cancer.

PLoS One 2014 11;9(4):e94226. Epub 2014 Apr 11.

Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094226PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984130PMC
December 2014

Treatment patterns and annual drug costs of biologic therapies across indications from the Humana commercial database.

J Manag Care Spec Pharm 2014 Dec;20(12):1236-44

One Technology Place, Rockland, MA 02370.

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http://dx.doi.org/10.18553/jmcp.2014.20.12.1236DOI Listing
December 2014

Persistence and dose escalation of tumor necrosis factor inhibitors in US veterans with rheumatoid arthritis.

J Rheumatol 2014 Oct 15;41(10):1935-43. Epub 2014 Aug 15.

From the Veterans Affairs Salt Lake City Health Care System; University of Utah School of Medicine, Salt Lake City, Utah; Denver Veterans Affairs (VA); University of Colorado, Denver, Colorado; University of Alabama at Birmingham, Birmingham, Alabama; the University of Nebraska Medical Center; Omaha VA, Omaha, Nebraska; the National Data Bank for Rheumatic Diseases, Wichita, Kansas; Dallas VA; University of Texas Southwestern, Dallas, Texas; Amgen Inc., Thousand Oaks, California, USA.G.W. Cannon, MD, Associate Chief of Staff of Academic Affiliations; S.L. DuVall, PhD, Associate Director, VA Informatics and Computing Infrastructure and Research Assistant Professor; C.L. Haroldsen, MSPH, Senior Programmer/Analyst; B.C. Sauer, PhD, MS, Associate Professor, Veterans Affairs Salt Lake City Health Care System, University of Utah School of Medicine; L. Caplan, MD, PhD, Associate Professor of Medicine/Rheumatology, Denver VA, University of Colorado; J.R. Curtis, MD, MS, MPH, William J. Koopman Endowed Professor in Rheumatology and Immunology, Director, University of Alabama Birmingham (UAB) Arthritis Clinical Intervention Program, Co-director, UAB Center for Education and Research on Therapeutics, Co-director, UAB PharmacoEpidemiology and Economic Research Group, University of Alabama at Birmingham; K. Michaud, PhD, Assistant Professor of Medicine, Co-director, University of Nebraska Medical Center, National Data Bank for Rheumatic Diseases; T.R. Mikuls, MD, Staff Physician and Researcher, Professor of Internal Medicine and Rheumatology, Omaha VA, University of Nebraska Medical Center; A. Reimold, MD, Chief, Rheumatology Section, Associate Professor of Medicine, Dallas VA, University of Texas Southwestern; D.H. Collier, MD, Clinical Research Medical Director; D.J. Harrison, PhD, Health Economics Director, Amgen Inc.; G.J. Joseph, PhD, Health Economics Senior Manager, former employee of Amgen Inc.

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http://dx.doi.org/10.3899/jrheum.140164DOI Listing
October 2014

Multidisciplinary urological engagement in translational renal cancer research.

BJU Int 2014 Oct 28;114(4):474-5. Epub 2014 Jul 28.

Edinburgh Urological Cancer Group, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/bju.12697DOI Listing
October 2014

Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer.

Biochem Soc Trans 2014 Aug;42(4):1017-23

*University of Edinburgh Division of Pathology Laboratories, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, U.K.

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http://dx.doi.org/10.1042/BST20140073DOI Listing
August 2014

The molecular biology of renal cancer: another piece of the puzzle.

Eur Urol 2014 Jul 14;66(1):85-6. Epub 2014 Mar 14.

Centre for Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1016/j.eururo.2014.03.004DOI Listing
July 2014

Medication effectiveness with the use of tumor necrosis factor inhibitors among Texas Medicaid patients diagnosed with rheumatoid arthritis.

J Manag Care Spec Pharm 2014 Jul;20(7):657-67

The University of Texas at Austin, 2409 University Ave., STOP A1930, Austin, TX 78712-1120.

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http://dx.doi.org/10.18553/jmcp.2014.20.7.657DOI Listing
July 2014

Quantification of tumour budding, lymphatic vessel density and invasion through image analysis in colorectal cancer.

J Transl Med 2014 Jun 1;12:156. Epub 2014 Jun 1.

Digital Pathology Unit, Laboratory medicine, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.

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http://dx.doi.org/10.1186/1479-5876-12-156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098951PMC
June 2014

Systems analysis of drug-induced receptor tyrosine kinase reprogramming following targeted mono- and combination anti-cancer therapy.

Cells 2014 Jun 10;3(2):563-91. Epub 2014 Jun 10.

Scottish Informatics, Mathematics, Biology and Statistics Centre (SIMBIOS), Abertay University, Dundee, DD1 1HG, United Kingdom.

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http://dx.doi.org/10.3390/cells3020563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092865PMC
June 2014

Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.

Protein Eng Des Sel 2014 May 25;27(5):145-55. Epub 2014 Mar 25.

Biomedical Health Research Centre, BioScreening Technology Group, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1093/protein/gzu007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000234PMC
May 2014

Use of microarray analysis to investigate EMT gene signatures.

Methods Mol Biol 2013 ;1046:85-95

Breakthrough Breast Cancer Research Unit, Western General Hospital, Edinburgh, UK.

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http://link.springer.com/content/pdf/10.1007%2F978-1-62703-5
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http://link.springer.com/10.1007/978-1-62703-538-5_5
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http://dx.doi.org/10.1007/978-1-62703-538-5_5DOI Listing
February 2014

Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations.

Front Oncol 2014 5;4:13. Epub 2014 Feb 5.

Centre for Research in Informatics and Systems Pathology (CRISP), University of Abertay Dundee , Dundee , UK.

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http://dx.doi.org/10.3389/fonc.2014.00013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914444PMC
February 2014

Human tissue in systems medicine.

FEBS J 2013 Dec 29;280(23):5949-56. Epub 2013 Oct 29.

Digital Pathology Unit, Laboratory Medicine, Royal Infirmary of Edinburgh, UK.

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http://dx.doi.org/10.1111/febs.12550DOI Listing
December 2013

The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer.

Clin Cancer Res 2013 Dec 15;19(24):6924-34. Epub 2013 Oct 15.

Authors' Affiliations: Barts Cancer Institute, Queen Mary University of London; Experimental Cancer Medicine Centre, University College; The Institute of Cancer Research; Guys and St Thomas' Hospital; The Royal Free Hospital London, London; Edinburgh Urological Cancer Group, University of Edinburgh, Edinburgh; Astra Zeneca, Manchester; School of Medicine, University of St Andrews, Fife, United Kingdom; National Cancer Institute, Amsterdam, the Netherlands; and University of Ghent, Ghent, Belgium.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1631DOI Listing
December 2013

Is the adult mouse striatum a hostile host for neural transplant survival?

Neuroreport 2013 Dec;24(18):1010-5

aBrain Repair Group, School of Biosciences bSchool of Medicine, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University cSchool of Health Sciences, Cardiff Metropolitan University, Cardiff, UK.

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http://dx.doi.org/10.1097/WNR.0000000000000066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942349PMC
December 2013

5-hydroxymethylcytosine profiling as an indicator of cellular state.

Epigenomics 2013 Dec;5(6):655-69

MRC Human Genetics Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.2217/epi.13.69DOI Listing
December 2013

The use of percutaneous lumbar fixation screws for bilateral pedicle fractures with an associated dislocation of a lumbar disc prosthesis.

Case Rep Orthop 2013 4;2013:676017. Epub 2013 Nov 4.

Princess Margaret Hospital, Windsor, Berkshire SL4 3SJ, UK.

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http://dx.doi.org/10.1155/2013/676017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835198PMC
December 2013

Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model.

Exp Neurol 2013 Oct 30;248:457-69. Epub 2013 Jul 30.

School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, Wales, UK.

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http://dx.doi.org/10.1016/j.expneurol.2013.07.014DOI Listing
October 2013

TMA Navigator: Network inference, patient stratification and survival analysis with tissue microarray data.

Nucleic Acids Res 2013 Jul 12;41(Web Server issue):W562-8. Epub 2013 Jun 12.

MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://academic.oup.com/nar/article/41/W1/W562/1113641/TMA-N
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http://dx.doi.org/10.1093/nar/gkt529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692046PMC
July 2013

New strategies for targeting the hypoxic tumour microenvironment in breast cancer.

Cancer Treat Rev 2013 Apr 12;39(2):171-9. Epub 2012 Oct 12.

Breakthrough Breast Unit and Division of Pathology, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1016/j.ctrv.2012.08.004DOI Listing
April 2013

Feedforward and feedback regulation of the MAPK and PI3K oscillatory circuit in breast cancer.

Cell Signal 2013 Jan 18;25(1):26-32. Epub 2012 Sep 18.

Centre for Research in Informatics and Systems Pathology (CRISP), University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1016/j.cellsig.2012.09.014DOI Listing
January 2013

Molecular pathology in therapeutics: where are we now, and where are we going?

Curr Drug Targets 2012 Nov;13(12):1473-4

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http://dx.doi.org/10.2174/138945012803530099DOI Listing
November 2012

A model of estrogen-related gene expression reveals non-linear effects in transcriptional response to tamoxifen.

BMC Syst Biol 2012 Nov 8;6:138. Epub 2012 Nov 8.

Centre for Synthetic and Systems Biology, University of Edinburgh, CH Waddington Building, the Kings Buildings, Mayfield Road, EH9 3JD, Edinburgh, UK.

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http://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0
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http://dx.doi.org/10.1186/1752-0509-6-138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573949PMC
November 2012