David J Gladstone

David J Gladstone

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David J Gladstone

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Technical Note: Quality assurance and relative dosimetry testing of a Co total body irradiator using optical imaging.

Med Phys 2019 Aug 25;46(8):3674-3678. Epub 2019 Jun 25.

Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1002/mp.13637DOI Listing
August 2019

Assessment of imaging Cherenkov and scintillation signals in head and neck radiotherapy.

Phys Med Biol 2019 Jul 18;64(14):145021. Epub 2019 Jul 18.

Thayer School of Engineering, Dartmouth College, Hanover, NH, United States of America. Author to whom any correspondence should be addressed.

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http://dx.doi.org/10.1088/1361-6560/ab25a3DOI Listing
July 2019

Characterization of a non-contact imaging scintillator-based dosimetry system for total skin electron therapy.

Phys Med Biol 2019 Jun 21;64(12):125025. Epub 2019 Jun 21.

Thayer School of Engineering, Dartmouth College, Hanover, NH, United States of America.

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http://dx.doi.org/10.1088/1361-6560/ab1d8aDOI Listing
June 2019

Technical Note: Time-gating to medical linear accelerator pulses: Stray radiation detector.

Med Phys 2019 Feb 14;46(2):1044-1048. Epub 2018 Dec 14.

Thayer School of Engineering, Dartmouth College, Hanover, NH, 03755, USA.

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http://dx.doi.org/10.1002/mp.13311DOI Listing
February 2019

Multi-beam scan analysis with a clinical LINAC for high resolution Cherenkov-excited molecular luminescence imaging in tissue.

Biomed Opt Express 2018 Sep 14;9(9):4217-4234. Epub 2018 Aug 14.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1364/BOE.9.004217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157777PMC
September 2018

Diagnostic accuracy and yield of screening tests for atrial fibrillation in the family practice setting: a multicentre cohort study.

CMAJ Open 2018 Jul-Sep;6(3):E308-E315. Epub 2018 Aug 2.

Libin Cardiovascular Institute of Alberta (Quinn), University of Calgary, Calgary, Alta.; Division of Neurology (Gladstone), Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, and Department of Medicine, University of Toronto, Toronto, Ont.; Department of Family and Community Medicine (Ivers), Women's College Hospital - University of Toronto, Toronto, Ont.; University of Alberta (Sandhu), Edmonton, Alta.; Department of Family Medicine (Dolovich), McMaster University, Hamilton, Ont.; Population Health Research Institute (Ling, Nakamya, Ramasundarahettige, Healey), McMaster University, Hamilton, Ont.; Mount Dennis Weston Health Centre (Frydrych), Toronto, Ont.; SKDS Research Inc. (Henein), Newmarket, Ont.; Ken Ng Family Practice (Ng), Markham, Ont.; Foothills Family Medical Centre (Congdon), Black Diamond, Alta.; Department of Family Medicine (Birtwhistle), Queen's University, Kingston, Ont.; Crowfoot Village Family Practice (Ward), Calgary, Alta.

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http://cmajopen.ca/lookup/doi/10.9778/cmajo.20180001
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http://dx.doi.org/10.9778/cmajo.20180001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182120PMC
August 2018

Carotid Intraplaque Hemorrhage in Patients with Embolic Stroke of Undetermined Source.

J Stroke Cerebrovasc Dis 2018 Jul 20;27(7):1956-1959. Epub 2018 Mar 20.

Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada; Sunnybrook Research Institute and Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.02.042DOI Listing
July 2018

Remote Cherenkov imaging-based quality assurance of a magnetic resonance image-guided radiotherapy system.

Med Phys 2018 Jun 3;45(6):2647-2659. Epub 2018 May 3.

Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.

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http://dx.doi.org/10.1002/mp.12919DOI Listing
June 2018

Radiotherapy-induced Cherenkov luminescence imaging in a human body phantom.

J Biomed Opt 2018 03;23(3):1-4

Thayer School of Engineering at Dartmouth, Hanover, New Hampshire, United States.

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http://dx.doi.org/10.1117/1.JBO.23.3.030504DOI Listing
March 2018

Cherenkov-excited Multi-Fluorophore Sensing in Tissue-Simulating Phantoms and In Vivo from External Beam Radiotherapy.

Radiat Res 2018 02 18;189(2):197-204. Epub 2017 Dec 18.

a   Thayer School of Engineering and.

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http://dx.doi.org/10.1667/RR14943.1DOI Listing
February 2018

Secondary stroke prevention services in Canada: a cross-sectional survey and geospatial analysis of resources, capacity and geographic access.

CMAJ Open 2018 Feb;6(1):E95-E102

Affiliations: Department of Geography and Planning (Jewett), University of Toronto, Toronto, Ont.; Department of Neurology and Neurosurgery (Harroud, Côté, Wein) and Department of Medicine (Harroud, Cote, Wein), McGill University, Montréal, Que.; Calgary Stroke Program (Hill, Smith, Demchuk), Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alta; Queen Elizabeth II Health Sciences Centre (Gubitz), Dalhousie University, Halifax, NS; Division of Neurology (Sahlas), Department of Medicine, McMaster University, Hamilton, Ont.; Sunnybrook Health Sciences Centre (Gladstone) and Hurvitz Brain Sciences Research Program (Gladstone), Sunnybrook Research Institute, Department of Medicine, University of Toronto; Heart and Stroke Foundation of Canada (Lindsay), Toronto, Ont.

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http://dx.doi.org/10.9778/cmajo.20170130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878947PMC
February 2018

Algorithm development for intrafraction radiotherapy beam edge verification from Cherenkov imaging.

J Med Imaging (Bellingham) 2018 Jan 2;5(1):015001. Epub 2018 Jan 2.

Dartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, Lebanon, New Hampshire, United States.

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http://dx.doi.org/10.1117/1.JMI.5.1.015001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749647PMC
January 2018

Screening for Atrial Fibrillation: A Report of the AF-SCREEN International Collaboration.

Circulation 2017 05;135(19):1851-1867

From Heart Research Institute, Charles Perkins Centre, and Concord Hospital Cardiology, University of Sydney, Australia (B.F.); St Georges Hospital, London, UK (J.C.); Johns Hopkins University, Baltimore, MD (H.C.); Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (J.S.H., D.C.); Karolinska Institute, Stockholm, Sweden (M.R., J.E., L.F., E.S.); The Shanghai Institute of Hypertension, Ruijin Hospital, Jiaotong University School of Medicine, China (J.W.); Brigham and Womens Hospital, Harvard Medical School, Boston, MA (C.M.A.); The George Institute for Global Health, Sydney, Australia (C.S.A.); Barts Health NHS Trust, London, UK (S.A.); National Heart, Lung, and Blood Institute and Boston University's Framingham Heart Study, MA (E.J.B.); University of Modena and Reggio Emilia, Italy (G.B.); Klinikum Coburg, Germany (J.B.); Odense University Hospital, Denmark (A.B.); Cardiovascular Research Centre, National Yang-Ming University, Taipei, Taiwan (T.- F.C.); University Hospital, Basel, Switzerland (D.C.); Université François Rabelais, Tours, France (L.F.); University of Birmingham, UK (D.A.F.); Mayo Clinic College of Medicine, Rochester, MN (B.J.G.); University of Toronto, Ontario, Canada (D.J.G., A.V.); Hackensack University Medical Centre, NJ (T.V.G.); Poche Centre, University of Sydney, Australia (K.G.); University of Western Australia, Perth (G.J.H.); Trinity College, Dublin, Ireland (J.H.); Royal Perth Hospital, University of Western Australia (G.S.H.); StopAfib.org, Dallas, TX (M.T.H.); Weill Cornell Medical College, New York (H.K.); Institute of Cardiovascular Sciences, University of Birmingham, UK (P.K.); SWBH and UHB NHS trusts, Birmingham, UK (P.K.); AFNET, Muenster, Germany (P.K.); Lankenau Institute for Medical Research, Wynnewood, OK (P.R.K.); University Hospital of Zurich, Switzerland (D.K.); Chinese University of Hong Kong (V.W.Y.L., B.P.Y.); University of Linköping, Sweden (L.-A.L.); University of Birmingham, UK; Aalborg University, Denmark (G.Y.H.L.); Arrhythmia Alliance, London, UK (T.L.); Charles Perkins Centre, University of Sydney, Australia (N.L.); Cliniques du Sud Luxembourg, Arlon, Belgium (G.H.M.); Institute for Epidemiology Statistics and Informatics, Frankfurt, Germany (C.M.); Edinburgh Napier University, UK (L.N.); Charles Perkins Centre, University of Sydney, Australia (J.O.); Duke University, Durham, NC (J.P.P.); University of Auckland, New Zealand (K.P.); University of Belgrade, Serbia (T.S.P.); KH der Elisabethinen, Ordensklinikum Linz, Austria (H.P.); University of Groningen, University Medical Centre Groningen, The Netherlands (M.R.); University of Alberta, Edmonton, Canada (R.K.S.); University Heart Centre, Hamburg, Germany (R.B.S.); The University of Hong Kong (C.-W.S.); Scripps Translational Science Institute, San Diego, CA (S.S.); Rigshospitalet, The Heart Centre, University of Copenhagen, Denmark (J.H.S.); Ospedale dell'Angelo Venice-Mestre, Venice, Italy (S.T.); Martini Hospital, Groningen, The Netherlands (R.G.T.); Stanford University, CA (M.P.T.); VA Palo Alto Health Care System, CA (M.P.T.); The Department of Medical Research, Bærum Hospital, Rud, Norway (A.T.); Department of General Practice, Academic Medical Center, Amsterdam, The Netherlands (S.B.U.); University of Groningen, University Medical Centre Groningen, The Netherlands (I.C.V.G.); and University of Göttingen, Germany (R.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026693DOI Listing
May 2017

Cardiac monitoring for detection of atrial fibrillation after TIA: A systematic review and meta-analysis.

Int J Stroke 2017 01 29;12(1):33-45. Epub 2016 Sep 29.

1 Division of Brain Sciences, Department of Stroke Medicine, Imperial College, London, UK.

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http://dx.doi.org/10.1177/1747493016669885DOI Listing
January 2017

Unattended Hospital and Home Sleep Apnea Testing Following Cerebrovascular Events.

J Stroke Cerebrovasc Dis 2017 Jan 4;26(1):143-149. Epub 2016 Oct 4.

Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre (HSC), Toronto, Ontario, Canada; Department of Medicine (Neurology), University of Toronto and Sunnybrook HSC, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.09.001DOI Listing
January 2017

Potential Cost-Effectiveness of Ambulatory Cardiac Rhythm Monitoring After Cryptogenic Stroke.

Stroke 2016 09 28;47(9):2380-5. Epub 2016 Jul 28.

From the Centre for Excellence in Economic Analysis Research (CLEAR), Toronto, ON, Canada (J.H.E.Y, J.S.H.); Applied Health Research Centre, Toronto, ON, Canada (K.E.T.); HUB Research Solutions, Li Ka Shing Centre for Healthcare Analytics Research and Training (LKS-CHART) (M.M.), Li Ka Shing Knowledge Institute, Toronto, ON, Canada (A.L.); St. Michael's Hospital, Toronto, ON, Canada (P.D.); Clinical Epidemiology Program, Ottawa Hospital Research Institute, The Ottawa Hospital; School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa; Institute of Clinical and Evaluative Sciences (ICES UOttawa), ON, Canada (K.T.); Institute of Health Policy, Management, and Evaluation (J.S.H., M.M., A.L.), Dalla Lana School of Public Health (K.E.T.), Leslie Dan Faculty of Pharmacy (J.S.H., M.M.), Division of Neurology (D.J.G.), and Department of Medicine (M.M., P.D., A.L., D.J.G.), University of Toronto, ON, Canada; Department of Public Health Sciences and Center for Healthcare Policy and Research, University of California, Davis, CA (J.S.H.); Division of Neurology, Department of Medicine, McMaster University, Hamilton, ON, Canada (M.S.); and Division of Neurology, Department of Medicine, Hurvitz Brain Sciences Program, and Regional Stroke Centre, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, ON, Canada (D.J.G.).

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http://dx.doi.org/10.1161/STROKEAHA.115.011979DOI Listing
September 2016

Underutilization of Ambulatory ECG Monitoring After Stroke and Transient Ischemic Attack: Missed Opportunities for Atrial Fibrillation Detection.

Stroke 2016 08 12;47(8):1982-9. Epub 2016 Jul 12.

From the Sunnybrook Research Institute and Hurvitz Brain Sciences Program (J.D.E., D.J.G.), L.C. Campbell Cognitive Neurology Research Unit and the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Sunnybrook Site (J.D.E.) and Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre (D.J.G.), Ontario, Canada; Division of Neurology (G.S., D.J.G.) and Division of Internal Medicine (M.K.K.), Department of Medicine, University of Toronto, Ontario, Canada; Division of General Internal Medicine and Toronto General Research Institute, University Health Network, Ontario, Canada (M.K.K.); and Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (M.K.K., J.F., G.S., D.J.G.).

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http://stroke.ahajournals.org/content/early/2016/07/12/STROK
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http://dx.doi.org/10.1161/STROKEAHA.115.012195DOI Listing
August 2016

Dose Specification for NRG Radiation Therapy Trials.

Int J Radiat Oncol Biol Phys 2016 08 7;95(5):1344-1345. Epub 2016 Apr 7.

Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan.

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http://dx.doi.org/10.1016/j.ijrobp.2016.03.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637531PMC
August 2016

Effect of apixaban on brain infarction and microbleeds: AVERROES-MRI assessment study.

Am Heart J 2016 Aug 17;178:145-50. Epub 2016 Apr 17.

Population Health Research Institute, McMaster University, and Hamilton Health Sciences, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/j.ahj.2016.03.019DOI Listing
August 2016

Predictors of Hospitalization in Patients With Transient Ischemic Attack or Minor Ischemic Stroke.

Can J Neurol Sci 2016 Jul 30;43(4):523-8. Epub 2016 Mar 30.

1Institute for Clinical Evaluative Sciences,Toronto,Canada.

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http://dx.doi.org/10.1017/cjn.2016.12DOI Listing
July 2016

Comparison of Cherenkov excited fluorescence and phosphorescence molecular sensing from tissue with external beam irradiation.

Phys Med Biol 2016 05 27;61(10):3955-68. Epub 2016 Apr 27.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA. MOE Key Laboratory of OptoElectronic Science and Technology for Medicine, Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fujian 350007, People's Republic of China.

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http://dx.doi.org/10.1088/0031-9155/61/10/3955DOI Listing
May 2016

Identifying obstructive sleep apnea after stroke/TIA: evaluating four simple screening tools.

Sleep Med 2016 05 1;21:133-9. Epub 2016 Feb 1.

Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre (HSC), Toronto, ON, Canada; LC Campbell Cognitive Neurology Research Unit, Sunnybrook Research Institute, University of Toronto, ON, Canada; Heart & Stroke Foundation Canadian Partnership for Stroke Recovery, Sunnybrook Site, Toronto, ON, Canada; Department of Medicine (Neurology), University of Toronto and Sunnybrook HSC, Toronto, ON, Canada; University of Toronto Stroke Program, Toronto, ON, Canada; Institute of Medical Science, Faculty of Medicine, School of Graduate Studies, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.sleep.2015.12.013DOI Listing
May 2016

Association between hospitalization and care after transient ischemic attack or minor stroke.

Neurology 2016 Apr 25;86(17):1582-9. Epub 2016 Mar 25.

From the Institute for Clinical Evaluative Sciences (M.K.K., R.H., J.F., P.C.A., F.L.S., D.J.G., M.S., J.V.T.), Toronto; Department of Medicine (M.K.K., F.L.S., D.J.G., L.K.C., J.V.T.), University of Toronto; Institute of Health Policy, Management and Evaluation (M.K.K., R.H., P.C.A., J.V.T.), Toronto; Division of General Internal Medicine and Toronto General Research Institute (M.K.K.) and Division of Neurology (F.L.S.), University Health Network, Toronto; Sunnybrook Research Institute (M.K.K., D.J.G., J.V.T.), Toronto; and Divisions of Neurology (D.J.G.) and Cardiology (J.V.T.), Sunnybrook Health Sciences Centre, Toronto, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000002614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844241PMC
April 2016

The Risk Stratification and Stroke Prevention Therapy Care Gap in Canadian Atrial Fibrillation Patients.

Can J Cardiol 2016 Mar 15;32(3):336-43. Epub 2015 Oct 15.

Terrence Donnelly Heart Centre, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada; Canadian Heart Research Centre, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2015.07.012DOI Listing
March 2016

Oral Anticoagulation for Stroke Prevention in Canadian Practice: Stroke Prevention and Rhythm Interventions in Atrial Fibrillation (SPRINT-AF) Registry(.).

Can J Cardiol 2016 Feb 2;32(2):204-10. Epub 2015 May 2.

Canadian Cardiovascular Research Network, Brampton, Ontario, Canada; McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2015.04.028DOI Listing
February 2016

Validation of the 9-Point and 24-Point Hematoma Expansion Prediction Scores and Derivation of the PREDICT A/B Scores.

Stroke 2015 Nov 13;46(11):3105-10. Epub 2015 Oct 13.

From the Division of Neuroradiology and Department of Medical Imaging (T.J.H., R.I.A., S.P.S.) and Division of Neurology, Department of Medicine and Brain Sciences Program (D.J.G.), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada; Calgary Stroke Program, Department of Clinical Neurosciences, Department of Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Canada (M.D.H., A.M.D.); Department of Medicine (Neurology) (D.D.) and Department of Diagnostic Imaging, Neuroradiology Section, The Ottawa Hospital (C.L.), University of Ottawa, Ottawa Hospital Research Institute, Ottawa, Canada; Department of Medicine and Institute of Health Policy Management and Evaluation, University of Toronto and Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Canada (A.L.); Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada (A.K.); Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital and Vall d'Hebron Research Institute, Barcelona, Spain (C.A.M., D.R.-L.); Department Neurology, Elblandklinikum Meissen, Academic Teaching Hospital of University of Dresden, Meissen, Germany (I.D.); Department of Neurology, Dr Josep Trueta University Hospital, Institut d'Investigació Biomèdica Girona (IDIBGi) Foundation, Girona, Spain (Y.S.); Second Department of Neurology, Institute of Psychiatry and Neurology of Warsaw, Warsaw, Poland (A.K.); Department of Medicine, Charles LeMoyne Hospital, University of Sherbrooke, Montreal, Canada (J.-M.B.); Division of Neurology, Department of Medicine, Dalhousie University, Halifax, Canada (G.G.); Department of Neurology, All India Institute of Medical Sciences, New Delhi, India (R.B., V.P.); Department of Neuromedicine, AMRI Hospitals, Mukundapur, Kolkata, India (J.R.); and Department of Neurology, Boston Medical Center, MA (C.S.K.).

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http://stroke.ahajournals.org/content/46/11/3105.full.pdf
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http://stroke.ahajournals.org/lookup/doi/10.1161/STROKEAHA.1
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http://dx.doi.org/10.1161/STROKEAHA.115.009893DOI Listing
November 2015

Quantitative analysis of brass compensators for commissioning of the Pinnacle planning system for IMRT.

J Appl Clin Med Phys 2015 11 8;16(6):130–138. Epub 2015 Nov 8.

Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth.

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http://dx.doi.org/10.1120/jacmp.v16i6.5531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690995PMC
November 2015

Rapid Assessment and Treatment of Transient Ischemic Attacks and Minor Stroke in Canadian Emergency Departments: Time for a Paradigm Shift.

Stroke 2015 Oct 27;46(10):2987-90. Epub 2015 Aug 27.

From the Departments of Clinical Neurosciences (N.K., M.D.H., A.M.D., S.B.C., M.G.), Emergency Medicine (E.L.), and Radiology (M.G.), Cumming School of Medicine, University of Calgary, Foothills Medical Centre, Calgary, AB; Department of Medicine, Dalhousie University (New Brunswick), Horizon Health Network, Saint John Regional Hospital, Saint John, NB (D.P.V.B.); Department of Neurology, Sherbrooke University, Charles-LeMoyne Hospital, Greenfield Park, QC (J.-M.B.); Department of Medicine (Neurology) (K.B., D.J.G.), University of Toronto, Sunnybrook Health Sciences Centre, Toronto, ON; Division of Neurology, Department of Medicine (B.B., K.B., T.J., K.K., A.S.), University of Alberta, University of Alberta Hospital, Edmonton, AB; Neurologue Spécialisée en Maladies Vasculaires Cérébrales, Centre Hospitalier Affilié Universitaire de Québec, Hôpital de l'Enfant-Jésus, Québec, QC (M.-C.C.); Division of Neurology, TIA and Minor Stroke (TAMS) Unit, Toronto Western Hospital, Toronto, ON (L.K.C.); Department of Neurology, Neurosurgery and Medicine, McGill University, McGill University Health Center Stroke Prevention Clinic, Montréal, QC (R.C.); Departments of Medicine, Epidemiology and Community Medicine, University of Ottawa, Ottawa, ON, Canada (D.D.); Neurologue Spécialisée en Maladies Vasculaires Cérébrales, Hôpital du Sacré-Coeur de Montréal, Montréal, QC (V.D.); Division of Neurology, University of British Columbia, Vancouver General Hospital, Vancouver, BC (T.S.F.); Section of Neurology, Department of Internal Medicine, University of Manitoba, Winnipeg, MN (E.G., A.T.); Department of Neuroscience, Faculty of Medicine, Université de Montréal, Neurovascular Programme, CHUM, Montréal, QC (L.G., S.L., C.O., A.Y.P.); Division of Neurology, Department of Medicine, Faculty of Medicine (G.J.G., S.J.P.), Dalhousie University, Nova Scotia Health Authority, Halifax, NS; Department of Emergency Medicine, University of British Columbia, Kelowna General Hospit

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http://dx.doi.org/10.1161/STROKEAHA.115.010454DOI Listing
October 2015

Cherenkov radiation fluence estimates in tissue for molecular imaging and therapy applications.

Phys Med Biol 2015 Sep 13;60(17):6701-18. Epub 2015 Aug 13.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1088/0031-9155/60/17/6701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145313PMC
September 2015

Optical cone beam tomography of Cherenkov-mediated signals for fast 3D dosimetry of x-ray photon beams in water.

Med Phys 2015 Jul;42(7):4127-36

Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03766.

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http://dx.doi.org/10.1118/1.4922135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474948PMC
July 2015

Atrial premature beats predict atrial fibrillation in cryptogenic stroke: results from the EMBRACE trial.

Stroke 2015 Apr 19;46(4):936-41. Epub 2015 Feb 19.

From the Division of Neurology (D.J.G.), Department of Medicine (D.J.G., P.D., M.S., M.M.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, Toronto, Ontario, Canada; University of Toronto Stroke Program, Toronto, Ontario, Canada (D.J.G.); Division of Neurology, Department of Medicine, and the Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, Ontario, Canada (D.J.G.); Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Toronto, Ontario, Canada (D.J.G.); Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada (M.M., V.P., K.E.T.); and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (J.S.H.).

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http://dx.doi.org/10.1161/STROKEAHA.115.008714DOI Listing
April 2015

Camera selection for real-time in vivo radiation treatment verification systems using Cherenkov imaging.

Med Phys 2015 Feb;42(2):994-1004

Department of Medicine, Geisel School of Medicine and Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03766.

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http://dx.doi.org/10.1118/1.4906249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312350PMC
February 2015

Cherenkoscopy based patient positioning validation and movement tracking during post-lumpectomy whole breast radiation therapy.

Phys Med Biol 2015 Jan 12;60(1):L1-14. Epub 2014 Dec 12.

Department of Physics and Astronomy, Dartmouth College, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1088/0031-9155/60/1/L1DOI Listing
January 2015

Patent foramen ovale closure vs medical therapy for stroke prevention: meta-analysis of randomized trials and review of heterogeneity in meta-analyses.

Can J Cardiol 2014 Oct 9;30(10):1216-24. Epub 2014 May 9.

Department of Cardiology, Boston Children's Hospital, and Harvard Medical School, Boston, Massachusetts, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.cjca.2014.05.004DOI Listing
October 2014

Cryptogenic stroke and atrial fibrillation.

N Engl J Med 2014 09;371(13):1260

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http://dx.doi.org/10.1056/NEJMc1409495DOI Listing
September 2014

Cherenkov video imaging allows for the first visualization of radiation therapy in real time.

Int J Radiat Oncol Biol Phys 2014 Jul 28;89(3):615-22. Epub 2014 Mar 28.

Department of Physics and Astronomy, Dartmouth College, Hanover, New Hampshire; Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire.

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https://linkinghub.elsevier.com/retrieve/pii/S03603016140013
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http://dx.doi.org/10.1016/j.ijrobp.2014.01.046DOI Listing
July 2014

Optical dosimetry of radiotherapy beams using Cherenkov radiation: the relationship between light emission and dose.

Phys Med Biol 2014 Jul 18;59(14):3789-811. Epub 2014 Jun 18.

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

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July 2014

The CLOQS trial protocol: a cluster-randomized trial evaluating a simple, low-cost intervention to reduce treatment times in acute stroke.

Int J Stroke 2014 Jun 5;9(4):525-8. Epub 2013 Sep 5.

Department of Medicine (Neurology), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/ijs.12066DOI Listing
June 2014

Atrial fibrillation in patients with cryptogenic stroke.

N Engl J Med 2014 Jun;370(26):2467-77

From the Division of Neurology (D.J.G.), Department of Medicine (D.J.G., P.D., A.L., M.S., J.A.B., L.K.C., D.S., M. Mehdiratta, K.B., M.K.K.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, the University of Toronto Stroke Program (D.J.G.), Division of Neurology, Department of Medicine, and Brain Sciences Program, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute (D.J.G., R.A.), the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (D.J.G.), and the Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital (V.P., K.E.T., J.H., H.V., A.L., M. Mamdani), Toronto, McMaster University, Hamilton, ON (M.S., D.J.S.), McGill University, Montreal (R.C.), University of Alberta, Edmonton (A.S., B.B.), Western University, London, ON (V.H., J.D.S.), Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB (S.B.C.), University of British Columbia, Vancouver (P.T., S.Y.), Queen's University, Kingston, ON (A.J.), Thunder Bay Regional Health Sciences Centre, Thunder Bay, ON (D.H.), Université Laval, Quebec City (S.V.), and Vancouver Island Health Research Centre, Victoria, BC (A.P.) - all in Canada; and the National University of Ireland, Galway (M.O.).

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http://dx.doi.org/10.1056/NEJMoa1311376DOI Listing
June 2014

Multicenter accuracy and interobserver agreement of spot sign identification in acute intracerebral hemorrhage.

Stroke 2014 Jan 26;45(1):107-12. Epub 2013 Nov 26.

From the Divisions of Neuroradiology (T.J.H., T.L.C., S.P.S., R.I.A.) and Division of Neurology, Department of Medicine, and Brain Sciences Program (D.J.G.), and Department of Emergency Medicine (J.C.), Sunnybrook Health Sciences and University of Toronto, Toronto, Canada; Department of Neurology, University of Cincinnati, OH (M.L.F., J.P.B.); Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calagary, Canada (A.M.D.); Department of Neurology, University of Ottawa and Ottawa Hospital Research Institute, Ottawa, Canada (D.D.); Departments of Medicine and Neurology (A.M., S.M.D.) and Neurointerventional Radiology (P.J.M.), Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia; and Department of Public Health Sciences, University of Toronto, Toronto, Canada (G.A.T.).

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January 2014

Real-time in vivo Cherenkoscopy imaging during external beam radiation therapy.

J Biomed Opt 2013 Nov;18(11):110504

Dartmouth College, Department of Physics and Astronomy, Hanover, New Hampshire 03755dDartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831064PMC
November 2013

Superficial dosimetry imaging based on Čerenkov emission for external beam radiotherapy with megavoltage x-ray beam.

Med Phys 2013 Oct;40(10):101914

Department of Physics and Astronomy, Dartmouth College, Hanover, New Hampshire 03755 and Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755.

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http://doi.wiley.com/10.1118/1.4821543
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790817PMC
October 2013

Superficial dosimetry imaging of Čerenkov emission in electron beam radiotherapy of phantoms.

Phys Med Biol 2013 Aug 24;58(16):5477-93. Epub 2013 Jul 24.

Department of Physics and Astronomy, Dartmouth College, Hanover, NH 03755, USA. Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143764PMC
August 2013

Čerenkov excited fluorescence tomography using external beam radiation.

Opt Lett 2013 Apr;38(8):1364-6

Thayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, New Hampshire 03755, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129509PMC
http://dx.doi.org/10.1364/OL.38.001364DOI Listing
April 2013

Three-dimensional Čerenkov tomography of energy deposition from ionizing radiation beams.

Opt Lett 2013 Mar;38(5):634-6

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698946PMC
http://dx.doi.org/10.1364/OL.38.000634DOI Listing
March 2013

Projection imaging of photon beams using Čerenkov-excited fluorescence.

Phys Med Biol 2013 Feb 14;58(3):601-19. Epub 2013 Jan 14.

Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1088/0031-9155/58/3/601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568662PMC
February 2013

Iron oxide nanoparticle enhancement of radiation cytotoxicity.

Proc SPIE Int Soc Opt Eng 2013 Feb;8584:85840J

Thayer School of Engineering, Dartmouth College, Hanover, NH USA 03755-8000.

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http://dx.doi.org/10.1117/12.2007701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187243PMC
February 2013

Projection imaging of photon beams by the Čerenkov effect.

Med Phys 2013 Jan;40(1):012101

Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1118/1.4770286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537759PMC
January 2013

Tumor bed dynamics after surgical resection of brain metastases: implications for postoperative radiosurgery.

Int J Radiat Oncol Biol Phys 2012 Nov 9;84(4):943-8. Epub 2012 Apr 9.

Section of Radiation Oncology, Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756-0001, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2012.01.067DOI Listing
November 2012

Impact of disability status on ischemic stroke costs in Canada in the first year.

Can J Neurol Sci 2012 Nov;39(6):793-800

Research Centre, Sunnybrook Health Sciences Centre Sunnybrook Health Sciences Centre, 2075 Bayview Aveune, E240, Toronto, Ontario, M4N 3M5, Canada.

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http://dx.doi.org/10.1017/s0317167100015638DOI Listing
November 2012

Severe hypomagnesemia associated with reversible subacute ataxia and cerebellar hyperintensities on MRI.

Neurologist 2012 Jul;18(4):223-5

Department of Medicine (Neurology), Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/NRL.0b013e31825bbf07DOI Listing
July 2012

Time-gated Cherenkov emission spectroscopy from linear accelerator irradiation of tissue phantoms.

Opt Lett 2012 Apr;37(7):1193-5

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1364/OL.37.001193DOI Listing
April 2012

Quantitative Cherenkov emission spectroscopy for tissue oxygenation assessment.

Opt Express 2012 Feb;20(5):5133-42

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1364/OE.20.005133DOI Listing
February 2012

New anticoagulants for atrial fibrillation: the beginning of a a new era in stroke prevention.

Can J Neurol Sci 2011 Sep;38(5):777-82

Regional Stroke Prevention Clinic, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room A442, Toronto, Ontario, M4N 3M5, Canada.

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http://dx.doi.org/10.1017/s0317167100012312DOI Listing
September 2011

Physically-based biodosimetry using in vivo EPR of teeth in patients undergoing total body irradiation.

Int J Radiat Biol 2011 Aug 23;87(8):766-75. Epub 2011 Jun 23.

Department of Diagnostic Radiology, Dartmouth Physically-based Biodosimetry Center for Medical Countermeasures against Radiation, Dartmouth Medical School, Hanover, New Hampshire, USA.

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http://dx.doi.org/10.3109/09553002.2011.583316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086327PMC
August 2011

Cerenkov emission induced by external beam radiation stimulates molecular fluorescence.

Med Phys 2011 Jul;38(7):4127-32

Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139507PMC
http://dx.doi.org/10.1118/1.3592646DOI Listing
July 2011

Stability of serrated gold coil markers in prostate localization.

J Appl Clin Med Phys 2011 Apr 18;12(3):3453. Epub 2011 Apr 18.

Department of Medicine,Radiation Oncology Section, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718644PMC
http://dx.doi.org/10.1120/jacmp.v12i3.3453DOI Listing
April 2011

The safety of proton pump inhibitors and clopidogrel in patients after stroke.

Stroke 2011 Jan 16;42(1):128-32. Epub 2010 Dec 16.

Sunnybrook Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.110.596643DOI Listing
January 2011

The spot sign is more common in the absence of multiple prior microbleeds.

Stroke 2010 Oct 2;41(10):2210-7. Epub 2010 Sep 2.

Division of Neuroradiology, Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.110.
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http://dx.doi.org/10.1161/STROKEAHA.110.593970DOI Listing
October 2010

The relationship between inflammatory markers and post stroke cognitive impairment.

J Geriatr Psychiatry Neurol 2010 Sep 2;23(3):199-205. Epub 2010 Jul 2.

Neuropsychopharmacology Research Group, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1177/0891988710373598DOI Listing
September 2010

Anticoagulation after anterior myocardial infarction and the risk of stroke.

PLoS One 2010 Aug 13;5(8):e12150. Epub 2010 Aug 13.

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921337PMC
August 2010

Effect of online medical control on prehospital Code Stroke triage.

CJEM 2010 Mar;12(2):103-10

Division of Emergency Medicine, University of Toronto, Toronto, Ontario, Canada.

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March 2010

A citywide prehospital protocol increases access to stroke thrombolysis in Toronto.

Stroke 2009 Dec 29;40(12):3841-4. Epub 2009 Oct 29.

North and East GTA-Ontario Regional Stroke Centre and Division of Neurology, Department of Medicine, and Brain Sciences Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://stroke.ahajournals.org/cgi/doi/10.1161/STROKEAHA.108.
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December 2009

Crescendo transient Aura attacks: a transient ischemic attack mimic caused by focal subarachnoid hemorrhage.

Stroke 2009 Dec 5;40(12):3725-9. Epub 2009 Nov 5.

Dr Thomas and Harriet Black Acute TIA Unit and Regional Stroke Prevention Clinic, Division of Neurology and Brain Sciences Program, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Toronto, Toronto, Ontario Canada.

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December 2009

Moderate carotid artery stenosis: MR imaging-depicted intraplaque hemorrhage predicts risk of cerebrovascular ischemic events in asymptomatic men.

Radiology 2009 Aug 9;252(2):502-8. Epub 2009 Jun 9.

Department of Diagnostic Imaging, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview St, Toronto, ON, Canada M4N 3M5.

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http://dx.doi.org/10.1148/radiol.2522080792DOI Listing
August 2009

Urgency of carotid endarterectomy for secondary stroke prevention: results from the Registry of the Canadian Stroke Network.

Stroke 2009 Aug 18;40(8):2776-82. Epub 2009 Jun 18.

Stroke Prevention Clinic, Division of Neurology and Regional Stroke Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room A442, Toronto, Ontario, Canada M4N 3M5.

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http://dx.doi.org/10.1161/STROKEAHA.109.547497DOI Listing
August 2009

Defining the CT angiography 'spot sign' in primary intracerebral hemorrhage.

Can J Neurol Sci 2009 Jul;36(4):456-61

Division of Neuroradiology, Department of Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1017/s0317167100007782DOI Listing
July 2009