David J Erle

David J Erle

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David J Erle

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Efficient RNP-Directed Human Gene Targeting Reveals SPDEF is Required for IL-13-Induced Mucostasis.

Am J Respir Cell Mol Biol 2019 Oct 9. Epub 2019 Oct 9.

University of California San Francisco, 8785, San Francisco, California, United States;

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http://dx.doi.org/10.1165/rcmb.2019-0266OCDOI Listing
October 2019

The epigenetic regulator ATF7ip inhibits expression, regulating Th17 responses.

J Exp Med 2019 Sep 19;216(9):2024-2037. Epub 2019 Jun 19.

Diabetes Center, University of California, San Francisco, San Francisco, CA

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http://dx.doi.org/10.1084/jem.20182316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719416PMC
September 2019

The airway epithelium in asthma.

Adv Immunol 2019 1;142:1-34. Epub 2019 Jul 1.

Lung Biology Center, University of California San Francisco, San Francisco, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.ai.2019.05.001DOI Listing
July 2019

A massively parallel 3' UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization.

Genome Res 2019 06 31;29(6):896-906. Epub 2019 May 31.

Department of Microbiology and Immunology and Sandler Asthma Basic Research Center, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1101/gr.242552.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581050PMC
June 2019

Integrative approach identifies corticosteroid response variant in diverse populations with asthma.

J Allergy Clin Immunol 2019 May 24;143(5):1791-1802. Epub 2018 Oct 24.

Center for Individualized and Genomic Medicine Research (CIGMA), Henry Ford Health System, Detroit, Mich; Department of Internal Medicine, Henry Ford Health System, Detroit, Mich. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183148
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http://dx.doi.org/10.1016/j.jaci.2018.09.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482107PMC
May 2019

Putting Mucins on the Map.

Am J Respir Crit Care Med 2019 Mar;199(6):681-682

1 Lung Biology Center University of California, San Francisco San Francisco, California.

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http://dx.doi.org/10.1164/rccm.201809-1818EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423107PMC
March 2019

Large Differences in Small RNA Composition Between Human Biofluids.

Cell Rep 2018 10;25(5):1346-1358

Lung Biology Center, University of California, San Francisco, UCSF Box 3118, San Francisco, CA 94143, USA; Cardiovascular Research Institute, University of California, San Francisco, UCSF Box 0130, San Francisco, CA 94143, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183157
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http://dx.doi.org/10.1016/j.celrep.2018.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261476PMC
October 2018

Widespread Effects of Chemokine 3' Untranslated Regions on mRNA Degradation and Protein Production in Human Cells.

J Immunol 2018 08 15;201(3):1053-1061. Epub 2018 Jun 15.

Lung Biology Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94158; and

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http://dx.doi.org/10.4049/jimmunol.1800114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057839PMC
August 2018

CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-Reactive CD4 Thymocytes and Supports Development of Natural Regulatory T Cells.

J Immunol 2018 02 10;200(4):1399-1412. Epub 2018 Jan 10.

Department of Microbiology and Immunology, Sandler Asthma Basic Research Center, University of California San Francisco, San Francisco, CA 94143; and

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1700768
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http://dx.doi.org/10.4049/jimmunol.1700768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809249PMC
February 2018

Airway Mucus and Asthma: The Role of MUC5AC and MUC5B.

J Clin Med 2017 Nov 29;6(12). Epub 2017 Nov 29.

Lung Biology Center, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.3390/jcm6120112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742801PMC
November 2017

CRISPR-Cas9-mediated functional dissection of 3'-UTRs.

Nucleic Acids Res 2017 Oct;45(18):10800-10810

Lung Biology Center, Department of Medicine, University of California San Francisco, 4th St, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1093/nar/gkx675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737544PMC
October 2017

miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis.

PLoS One 2016 30;11(6):e0158367. Epub 2016 Jun 30.

Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158367PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928999PMC
July 2017

Chitin-Induced Airway Epithelial Cell Innate Immune Responses Are Inhibited by Carvacrol/Thymol.

PLoS One 2016 27;11(7):e0159459. Epub 2016 Jul 27.

Lung Biology Center, Department of Medicine, University of California, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159459PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962986PMC
July 2017

Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease.

Cell 2017 04;169(3):497-509.e13

Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.03.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444468PMC
April 2017

A tissue checkpoint regulates type 2 immunity.

Nat Immunol 2016 Dec 17;17(12):1381-1387. Epub 2016 Oct 17.

Department of Medicine, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/ni.3582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5275767PMC
December 2016

Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD.

Eur Respir J 2016 06 10;47(6):1645-56. Epub 2016 Mar 10.

Division of Physiological Chemistry 2, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden Both authors contributed equally

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http://dx.doi.org/10.1183/13993003.01080-2015DOI Listing
June 2016

Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells.

PLoS One 2015 13;10(8):e0135440. Epub 2015 Aug 13.

UCSF Diabetes Center, University of California San Francisco, San Francisco, California, United States of America; Department of Medicine, University of California San Francisco, San Francisco, California, United States of America; Department of Pathology, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135440PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535774PMC
May 2016

MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.

Immunity 2016 Apr 2;44(4):821-32. Epub 2016 Feb 2.

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838571PMC
April 2016

Massively Parallel Identification of Regulatory Variants in Asthma.

Ann Am Thorac Soc 2016 Mar;13 Suppl 1:S104

University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1513/AnnalsATS.201508-523MGDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015739PMC
March 2016

Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.

Am J Physiol Lung Cell Mol Physiol 2015 Jun 20;308(11):L1102-13. Epub 2015 Mar 20.

Departments of Medicine and Anesthesia, University of California-San Francisco, San Francisco, California; Cardiovascular Research Institute, University of California-San Francisco, San Francisco, California; Department of Medicine, Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California-San Francisco, San Francisco, California; and.

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http://ajplung.physiology.org/content/ajplung/308/11/L1102.f
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http://ajplung.physiology.org/lookup/doi/10.1152/ajplung.003
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http://dx.doi.org/10.1152/ajplung.00380.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451399PMC
June 2015

IL-17 and "TH2-high" asthma: Adding fuel to the fire?

J Allergy Clin Immunol 2014 Nov 28;134(5):1187-8. Epub 2014 Aug 28.

Department of Medicine, University of California San Francisco, San Francisco, Calif. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.07.034DOI Listing
November 2014

Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma.

Am J Respir Crit Care Med 2014 Sep;190(6):639-48

1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, and.

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http://dx.doi.org/10.1164/rccm.201403-0505OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214109PMC
September 2014

The cell biology of asthma.

J Cell Biol 2014 Jun;205(5):621-31

Lung Biology Center and Department of Medicine, University of California, San Francisco, San Francisco, CA 94143

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http://dx.doi.org/10.1083/jcb.201401050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050726PMC
June 2014

Massively parallel functional annotation of 3' untranslated regions.

Nat Biotechnol 2014 Apr 16;32(4):387-91. Epub 2014 Mar 16.

Lung Biology Center, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nbt.2851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981918PMC
April 2014

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.

Nat Immunol 2014 Mar 26;15(3):258-65. Epub 2014 Jan 26.

1] Diabetes Center, University of California San Francisco, San Francisco, California, USA. [2] Department of Medicine, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/ni.2820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172453PMC
March 2014

Hands-on workshops as an effective means of learning advanced technologies including genomics, proteomics and bioinformatics.

Genomics Proteomics Bioinformatics 2013 Dec 6;11(6):368-77. Epub 2013 Dec 6.

Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1016/j.gpb.2013.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049090PMC
December 2013

An integrated nano-scale approach to profile miRNAs in limited clinical samples.

Am J Clin Exp Immunol 2012 Nov;1(2):70-89

Sandler Asthma Basic Research Center, University of California San Francisco, San Francisco, CA, USA ; Division of Infection, Inflammation and Immunity, University of outhampton, School of Medicine, Southampton NIHR Respiratory Biomedical Research Unit, Sir Henry Wellcome Laboratories, Southampton General Hospital, Southampton, UK ; Pulmonary and Critical Care Division, Department of Medicine, University of California San Francisco.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538381PMC
November 2012

AGR2 is induced in asthma and promotes allergen-induced mucin overproduction.

Am J Respir Cell Mol Biol 2012 Aug 8;47(2):178-85. Epub 2012 Mar 8.

Lung Biology Center, Department of Medicine, University of California San Francisco, USA.

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http://dx.doi.org/10.1165/rcmb.2011-0421OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423459PMC
August 2012

Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics.

BMC Med Genomics 2012 Jun 19;5:27. Epub 2012 Jun 19.

Laboratory of Bioinformatics and Genomics, World Premier International Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1186/1755-8794-5-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408345PMC
June 2012

The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile.

Proc Natl Acad Sci U S A 2011 Sep 29;108(37):15201-6. Epub 2011 Aug 29.

Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1103746108
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http://dx.doi.org/10.1073/pnas.1103746108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174577PMC
September 2011

Toward a systematic understanding of mRNA 3' untranslated regions.

Proc Am Thorac Soc 2011 May;8(2):163-6

Department of Medicine, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1513/pats.201007-054MSDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131834PMC
May 2011

An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors.

PLoS One 2011 Jan 4;6(1):e16004. Epub 2011 Jan 4.

Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016004PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014940PMC
January 2011

Expression of IL-4 receptor alpha on smooth muscle cells is not necessary for development of experimental allergic asthma.

J Allergy Clin Immunol 2010 Aug 25;126(2):347-54. Epub 2010 Jun 25.

Division of Immunology, Institute of Infectious Disease and Molecular Medicine, Health Sciences Faculty, University of Cape Town and International Centre for Genetic Engineering and Biotechnology, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.jaci.2010.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917502PMC
August 2010

Systemically dispersed innate IL-13-expressing cells in type 2 immunity.

Proc Natl Acad Sci U S A 2010 Jun 7;107(25):11489-94. Epub 2010 Jun 7.

Howard Hughes Medical Institute, Department of Medicine, University of California, San Francisco, CA 94143-0795, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1003988107
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http://dx.doi.org/10.1073/pnas.1003988107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895098PMC
June 2010

Intelectin is required for IL-13-induced monocyte chemotactic protein-1 and -3 expression in lung epithelial cells and promotes allergic airway inflammation.

Am J Physiol Lung Cell Mol Physiol 2010 Mar 4;298(3):L290-6. Epub 2009 Dec 4.

Division of Respiratory Diseases, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1152/ajplung.90612.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838671PMC
March 2010

Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.

Am J Respir Crit Care Med 2009 Oct 23;180(7):603-10. Epub 2009 Jul 23.

Lung Biology Center, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1164/rccm.200811-1768OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753788PMC
October 2009

Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking.

PLoS One 2009 Aug 11;4(8):e6580. Epub 2009 Aug 11.

Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006580PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719063PMC
August 2009

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.

Proc Natl Acad Sci U S A 2009 Apr 9;106(17):6950-5. Epub 2009 Apr 9.

Lung Biology Center and Program in Immunology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1073/pnas.0808722106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678445PMC
April 2009

CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation.

J Immunol 2009 Jan;182(1):623-35

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718444PMC
http://dx.doi.org/10.4049/jimmunol.182.1.623DOI Listing
January 2009

Disease-specific gene expression profiling in multiple models of lung disease.

Am J Respir Crit Care Med 2008 Feb 20;177(4):376-87. Epub 2007 Nov 20.

Cincinnati Children's Hospital Medical Center/Division of Immunobiology, 3333 Burnet Avenue, MLC 7038, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1164/rccm.200702-333OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258439PMC
February 2008

Integrin beta6 mediates phospholipid and collectin homeostasis by activation of latent TGF-beta1.

Am J Respir Cell Mol Biol 2007 Dec 19;37(6):651-9. Epub 2007 Jul 19.

Lung Biology Center, Department of Medicine, San Francisco General Hospital, California, USA.

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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2006-0428OC
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http://dx.doi.org/10.1165/rcmb.2006-0428OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219547PMC
December 2007

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids.

Proc Natl Acad Sci U S A 2007 Oct 26;104(40):15858-63. Epub 2007 Sep 26.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1073/pnas.0707413104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000427PMC
October 2007

Progress toward a systems biology approach to acute lung injury.

Am J Physiol Lung Cell Mol Physiol 2007 Aug 15;293(2):L290-1. Epub 2007 Jun 15.

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http://www.physiology.org/doi/10.1152/ajplung.00220.2007
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http://dx.doi.org/10.1152/ajplung.00220.2007DOI Listing
August 2007

IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production.

Am J Respir Cell Mol Biol 2007 Feb 15;36(2):244-53. Epub 2006 Sep 15.

Department of Medicine, University of California, San Francisco, CA 94143-2922, USA.

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http://dx.doi.org/10.1165/rcmb.2006-0180OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899314PMC
February 2007

The asthma channel? Stay tuned . . .

Am J Respir Crit Care Med 2006 Jun;173(11):1181-2

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http://www.atsjournals.org/doi/abs/10.1164/rccm.2603006
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http://dx.doi.org/10.1164/rccm.2603006DOI Listing
June 2006

A distinctive alveolar macrophage activation state induced by cigarette smoking.

Am J Respir Crit Care Med 2005 Dec 15;172(11):1383-92. Epub 2005 Sep 15.

UCSF-Mission Bay Rock Hall, Room 545, 1550 4th Street, San Francisco, CA 94158, USA.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.200505-686OC
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http://dx.doi.org/10.1164/rccm.200505-686OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718436PMC
December 2005

IL-4 receptor signaling in Clara cells is required for allergen-induced mucus production.

J Immunol 2005 Sep;175(6):3746-52

Lung Biology Center, Department of Medicine, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.4049/jimmunol.175.6.3746DOI Listing
September 2005

Dissecting asthma using focused transgenic modeling and functional genomics.

J Allergy Clin Immunol 2005 Aug;116(2):305-11

Department of Medicine, Allergy-Immunology Division, Northwestern University Feinberg School of Medicine, Chicago, USA.

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http://dx.doi.org/10.1016/j.jaci.2005.03.024DOI Listing
August 2005

Increased DNA microarray hybridization specificity using sscDNA targets.

BMC Genomics 2005 Apr 22;6:57. Epub 2005 Apr 22.

Gladstone Institute of Cardiovascular Disease, The J. David Gladstone Institutes, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1186/1471-2164-6-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090574PMC
April 2005

Differential gene expression by integrin beta 7+ and beta 7- memory T helper cells.

BMC Immunol 2004 Jul 5;5:13. Epub 2004 Jul 5.

Department of Medicine, University of California, San Francisco, CA 94143-0854, USA.

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http://dx.doi.org/10.1186/1471-2172-5-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC476736PMC
July 2004

Asthma investigators begin to reap the fruits of genomics.

Genome Biol 2003 27;4(11):232. Epub 2003 Oct 27.

Lung Biology Center, Department of Medicine, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1186/gb-2003-4-11-232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC329104PMC
March 2004

Abnormal alveolar development associated with elevated adenine nucleosides.

Am J Respir Cell Mol Biol 2004 Jan 10;30(1):38-50. Epub 2003 Jul 10.

Department of Biochemistry and Molecular Biology, University of Texas-Houston Medical School, 6431 Fannin, Houston, TX 77030, USA.

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http://dx.doi.org/10.1165/rcmb.2003-0102OCDOI Listing
January 2004

Spotted long oligonucleotide arrays for human gene expression analysis.

Genome Res 2003 Jul 12;13(7):1775-85. Epub 2003 Jun 12.

Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1101/gr.1048803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC403751PMC
July 2003

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma.

Nat Med 2002 Aug 1;8(8):885-9. Epub 2002 Jul 1.

Lung Biology Center, Department of Medicine and Cardiovascular Research Institute, University of California San Francisco School of Medicine, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nm734DOI Listing
August 2002

Use of spotted oligonucleotide arrays for large-scale analysis of mammalian gene expression.

Chest 2002 Mar;121(3 Suppl):80S

Functional Genomics Core Facility, UCSF Sandler Center for Basic Research in Asthma, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1378/chest.121.3_suppl.80sDOI Listing
March 2002

The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells.

Am J Respir Cell Mol Biol 2002 Feb;26(2):202-8

Lung Biology Center, Program in Immunology, University of California San Francisco, Box 0854, San Francisco, CA 94143-0854, USA.

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http://dx.doi.org/10.1165/ajrcmb.26.2.4600DOI Listing
February 2002