Publications by authors named "David J Cousins"

33 Publications

Differential expression of functional chemokine receptors on human blood and lung group 2 innate lymphoid cells.

J Allergy Clin Immunol 2019 01 8;143(1):410-413.e9. Epub 2018 Sep 8.

Department of Infection, Immunity and Inflammation, NIHR Leicester Biomedical Research Centre - Respiratory, Leicester Institute for Lung Health, University of Leicester, Leicestershire, United Kingdom; MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom. Electronic address:

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January 2019

Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter.

PLoS One 2018 29;13(8):e0200040. Epub 2018 Aug 29.

MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, Guy's Hospital, London, United Kingdom.

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January 2019

miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells.

Mol Immunol 2018 09 3;101:419-428. Epub 2018 Aug 3.

School of Immunology & Microbial Sciences, King's College London, UK; Medical Research Council and Asthma UK Centre, Allergic Mechanisms in Asthma, London, UK. Electronic address:

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September 2018

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.

Sci Immunol 2017 12;2(18)

Medical Research Council (MRC) Human Immunology Unit, Weatherall Institute of Molecular Medicine, National Institute for Health Research (NIHR) Biomedical Research Centre, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

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December 2017

Pinning allergies on pathogenic T2 cells.

Authors:
David J Cousins

Sci Transl Med 2017 Aug;9(401)

Department of Infection, Immunity and Inflammation, National Institute for Health Research Leicester Biomedical Research Centre, Leicester Institute for Lung Health, University of Leicester, Leicester LE3 9QP, UK. Email:

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August 2017

Human group 2 innate lymphoid cells do not express the IL-5 receptor.

J Allergy Clin Immunol 2017 11 10;140(5):1430-1433.e4. Epub 2017 May 10.

Department of Infection, Immunity and Inflammation, University of Leicester, Leicestershire, United Kingdom; MRC &Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.

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November 2017

Intradermal grass pollen immunotherapy increases T2 and IgE responses and worsens respiratory allergic symptoms.

J Allergy Clin Immunol 2017 Jun 20;139(6):1830-1839.e13. Epub 2016 Oct 20.

Division of Asthma, Allergy and Lung Biology, King's College London, School of Medicine, Guy's Hospital, London, United Kingdom; MRC-Asthma UK Centre for Allergic Mechanisms of Asthma, London, United Kingdom. Electronic address:

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June 2017

IL-25/IL-33-responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa.

J Allergy Clin Immunol 2016 05 10;137(5):1514-24. Epub 2015 Dec 10.

Division of Asthma, Allergy and Lung Biology, Guy's Hospital, King's College London, London, United Kingdom; Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom. Electronic address:

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May 2016

Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production.

J Immunol 2016 Jan 18;196(1):45-54. Epub 2015 Nov 18.

Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, United Kingdom;

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January 2016

Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.

J Allergy Clin Immunol 2015 Mar 12;135(3):824-7.e3. Epub 2014 Nov 12.

MRC and Asthma UK Centre for Allergic Mechanisms of Asthma, King's College London, Guy's Hospital, London, United Kingdom. Electronic address:

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March 2015

IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy.

J Allergy Clin Immunol 2014 Dec 10;134(6):1329-1338.e10. Epub 2014 Aug 10.

Division of Asthma, Allergy and Lung Biology, King's College London, and Guys' Hospital, London, United Kingdom; MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, and Guys' Hospital, London, United Kingdom. Electronic address:

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December 2014

Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy.

J Immunol 2014 Apr 21;192(7):3419-27. Epub 2014 Feb 21.

Leukocyte Biology Section, Medical Research Council-Asthma UK Centre in Allergic Mechanisms of Asthma, National Heart and Lung Institute Division, Faculty of Medicine, Imperial College London, London SW7 2AZ, United Kingdom;

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April 2014

Fibronectin is a TH1-specific molecule in human subjects.

J Allergy Clin Immunol 2009 Sep 9;124(3):528-35, 535.e1-5. Epub 2009 Jul 9.

Medical Research Council and Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, Guy's Hospital, London, United Kingdom.

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September 2009

Chromatin structure and DNA methylation of the IL-4 gene in human T(H)2 cells.

Chromosome Res 2009 12;17(4):485-96. Epub 2009 Jun 12.

Santangelo Consulting Pty Ltd., Singapore, Singapore.

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November 2009

Therapeutic approaches for control of transcription factors in allergic disease.

J Allergy Clin Immunol 2008 Apr;121(4):803-9; quiz 810-1

MRC-Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.

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April 2008

Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.

Proc Natl Acad Sci U S A 2007 Jul 18;104(30):12440-4. Epub 2007 Jul 18.

Medical Research Council--Asthma U.K. Centre in Allergic Mechanisms of Asthma and Genomics Centre, King's College London, London SE1 9RT, United Kingdom.

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July 2007

Regulation of GM-CSF expression by the transcription factor c-Maf.

J Allergy Clin Immunol 2007 Jul 15;120(1):56-63. Epub 2007 May 15.

Medical Research Council and Asthma UK Center in Allergic Mechanisms of Asthma, King's College London, Guy's Hospital, London, UK.

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July 2007

IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.

Int Immunol 2005 Mar 14;17(3):297-306. Epub 2005 Feb 14.

Department of Immunology, Institute of Ophthalmology, University College London and Moorfields Eye Hospital, NHS Foundation Trust, 11-43 Bath Street, London EC1V 9EL, UK.

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March 2005