David I Stuart

David I Stuart

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Glutathione facilitates enterovirus assembly by binding at a druggable pocket.

Commun Biol 2020 3;3. Epub 2020 Jan 3.

1Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN UK.

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http://dx.doi.org/10.1038/s42003-019-0722-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941975PMC
January 2020

Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10.

Nat Commun 2020 01 7;11(1):38. Epub 2020 Jan 7.

Division of Structural Biology, The Wellcome Centre for Human Genetics, University of Oxford, Headington, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1038/s41467-019-13936-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946704PMC
January 2020

Glutathione facilitates enterovirus assembly by binding at a druggable pocket.

Commun Biol 2020 Jan 3;3(1). Epub 2020 Jan 3.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1038/s42003-019-0722-xDOI Listing
January 2020

The role of the light chain in the structure and binding activity of two cattle antibodies that neutralize bovine respiratory syncytial virus.

Mol Immunol 2019 08 14;112:123-130. Epub 2019 May 14.

The Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN, UK; Research Complex at Harwell, R92 Rutherford Appleton Laboratory, Didcot, OX11 0FA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2019.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677920PMC
August 2019

Atomic structure of the Epstein-Barr virus portal.

Nat Commun 2019 08 29;10(1):3891. Epub 2019 Aug 29.

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10-12, 08028, Barcelona, Spain.

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http://dx.doi.org/10.1038/s41467-019-11706-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715670PMC
August 2019

Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus.

Nature 2019 06 29;570(7760):252-256. Epub 2019 May 29.

Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41586-019-1229-9DOI Listing
June 2019

Hepatitis A Virus Capsid Structure.

Cold Spring Harb Perspect Med 2019 05 1;9(5). Epub 2019 May 1.

Division of Structural Biology, The Henry Wellcome Building for Genomic Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1101/cshperspect.a031807DOI Listing
May 2019

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.

Nat Microbiol 2019 03 10;4(3):414-419. Epub 2018 Dec 10.

Division of Structural Biology, The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41564-018-0319-zDOI Listing
March 2019

Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library.

J Med Chem 2019 03 6;62(6):2928-2937. Epub 2019 Mar 6.

Division of Structural Biology , University of Oxford , The Henry Wellcome Building for Genomic Medicine , Headington, Oxford OX3 7BN , U.K.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441942PMC
March 2019

Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.

Nat Commun 2019 03 29;10(1):1456. Epub 2019 Mar 29.

Division of Structural Biology, University of Oxford, Wellcome Centre for Human Genetics, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1038/s41467-019-09451-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441041PMC
March 2019

Redundant Late Domain Functions of Tandem VP2 YPXL Motifs in Nonlytic Cellular Egress of Quasi-enveloped Hepatitis A Virus.

J Virol 2018 12 12;92(23). Epub 2018 Nov 12.

Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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http://dx.doi.org/10.1128/JVI.01308-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232465PMC
December 2018

Seneca Valley virus attachment and uncoating mediated by its receptor anthrax toxin receptor 1.

Proc Natl Acad Sci U S A 2018 12 4;115(51):13087-13092. Epub 2018 Dec 4.

Drug Discovery Center for Infectious Disease, College of Pharmacy, Nankai University, 300071 Tianjin, China.

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http://dx.doi.org/10.1073/pnas.1814309115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304951PMC
December 2018

Machining protein microcrystals for structure determination by electron diffraction.

Proc Natl Acad Sci U S A 2018 09 31;115(38):9569-9573. Epub 2018 Aug 31.

Division of Structural Biology, University of Oxford, Headington, Oxford OX3 7BN, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1809978115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156647PMC
September 2018

Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71.

mBio 2018 07 3;9(4). Epub 2018 Jul 3.

National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

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http://dx.doi.org/10.1128/mBio.01013-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030555PMC
July 2018

Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.

J Med Chem 2018 06 21;61(11):4938-4945. Epub 2018 May 21.

Division of Structural Biology , University of Oxford , The Henry Wellcome Building for Genomic Medicine , Headington, Oxford OX3 7BN , U.K.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00350DOI Listing
June 2018

Building the atomic model of a boreal lake virus of unknown fold in a 3.9 Å cryo-EM map.

J Struct Biol 2018 04 27;202(1):94-99. Epub 2017 Oct 27.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, UK; Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot OX11 0DE, UK.

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http://dx.doi.org/10.1016/j.jsb.2017.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847487PMC
April 2018

Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection.

J Med Chem 2018 02 16;61(3):724-733. Epub 2018 Jan 16.

Division of Structural Biology, University of Oxford , The Henry Wellcome Building for Genomic Medicine, Headington, Oxford, OX3 7BN, U.K.

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http://dx.doi.org/10.1021/acs.jmedchem.7b01249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808380PMC
February 2018

Towards in cellulo virus crystallography.

Sci Rep 2018 02 28;8(1):3771. Epub 2018 Feb 28.

Molecular and Integrative Biosciences Research Program, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/s41598-018-21693-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830620PMC
February 2018

Where is crystallography going?

Acta Crystallogr D Struct Biol 2018 Feb 1;74(Pt 2):152-166. Epub 2018 Feb 1.

Science Division, Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.

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http://dx.doi.org/10.1107/S2059798317016709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947779PMC
February 2018

Virus found in a boreal lake links ssDNA and dsDNA viruses.

Proc Natl Acad Sci U S A 2017 08 17;114(31):8378-8383. Epub 2017 Jul 17.

Centre of Excellence in Biological Interactions, Department of Biological and Environmental Science, University of Jyväskylä, 40014 Jyväskylä, Finland;

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http://dx.doi.org/10.1073/pnas.1703834114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547622PMC
August 2017

SAT2 Foot-and-Mouth Disease Virus Structurally Modified for Increased Thermostability.

J Virol 2017 05 28;91(10). Epub 2017 Apr 28.

Transboundary Animal Disease Programme, ARC-Onderstepoort Veterinary Institute, Onderstepoort, South Africa

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http://dx.doi.org/10.1128/JVI.02312-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411616PMC
May 2017

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus.

Nat Commun 2017 05 23;8:15408. Epub 2017 May 23.

Division of Structural Biology, The Nuffield Department of Medicine, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/ncomms15408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457520PMC
May 2017

Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.

Nat Commun 2017 03 13;8:14814. Epub 2017 Mar 13.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/ncomms14814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355851PMC
March 2017

Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site.

Proc Natl Acad Sci U S A 2017 01 10;114(4):770-775. Epub 2017 Jan 10.

National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science, Beijing 100101, China;

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http://dx.doi.org/10.1073/pnas.1616502114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278457PMC
January 2017

Structure of human Aichi virus and implications for receptor binding.

Nat Microbiol 2016 Sep 5;1(11):16150. Epub 2016 Sep 5.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/nmicrobiol.2016.150DOI Listing
September 2016

The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly.

Structure 2016 07 2;24(7):1068-80. Epub 2016 Jun 2.

Laboratory of Structural Biology Research, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938712PMC
July 2016

Toremifene interacts with and destabilizes the Ebola virus glycoprotein.

Nature 2016 07 29;535(7610):169-172. Epub 2016 Jun 29.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1038/nature18615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947387PMC
July 2016

The democratization of cryo-EM.

Nat Methods 2016 07;13(8):607-8

Structural Biology Unit, CICbioGUNE, CIBERehd, Derio, Spain.

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http://dx.doi.org/10.1038/nmeth.3946DOI Listing
July 2016

Structure of glycosylated NPC1 luminal domain C reveals insights into NPC2 and Ebola virus interactions.

FEBS Lett 2016 Mar 23;590(5):605-12. Epub 2016 Feb 23.

Division of Structural Biology, University of Oxford, Headington, Oxford, UK.

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http://dx.doi.org/10.1002/1873-3468.12089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819692PMC
March 2016

Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms.

FEBS Lett 2016 Jan 23;590(2):288-97. Epub 2016 Jan 23.

Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Oxford, UK.

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http://doi.wiley.com/10.1002/1873-3468.12054
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http://dx.doi.org/10.1002/1873-3468.12054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764023PMC
January 2016

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.

Nature 2015 Nov 26;527(7576):114-7. Epub 2015 Oct 26.

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

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http://dx.doi.org/10.1038/nature15525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783868PMC
November 2015

Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes.

Nat Commun 2015 Nov 4;6:8843. Epub 2015 Nov 4.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/ncomms9843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667630PMC
November 2015

Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity.

J Virol 2015 Oct 12;89(20):10500-11. Epub 2015 Aug 12.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford, United Kingdom Diamond Light Sources, Harwell Science and Innovation Campus, Didcot, United Kingdom

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http://jvi.asm.org/lookup/doi/10.1128/JVI.01102-15
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http://dx.doi.org/10.1128/JVI.01102-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580203PMC
October 2015

Polyhedra structures and the evolution of the insect viruses.

J Struct Biol 2015 Oct 18;192(1):88-99. Epub 2015 Aug 18.

Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, Oxfordshire OX3 7BN, United Kingdom; Diamond House, Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2015.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597613PMC
October 2015

Diamond Light Source: status and perspectives.

Philos Trans A Math Phys Eng Sci 2015 Mar;373(2036)

Diamond Light Source, University College London, 17-19 Gordon Street, London WC1H 0AH, UK Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1098/rsta.2013.0161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308985PMC
March 2015

Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.

Nat Commun 2015 Mar 9;6:6435. Epub 2015 Mar 9.

1] Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, Oxfordshire OX3 7BN, UK [2] Diamond House, Diamond Light Source, Harwell Science &Innovation Campus, Didcot, Oxfordshire OX11 0DE, UK.

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http://www.nature.com/articles/ncomms7435
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http://dx.doi.org/10.1038/ncomms7435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403592PMC
March 2015

Hepatitis A virus and the origins of picornaviruses.

Nature 2015 Jan 19;517(7532):85-88. Epub 2014 Oct 19.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford, UK.

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http://dx.doi.org/10.1038/nature13806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773894PMC
January 2015

A national facility for biological cryo-electron microscopy.

Acta Crystallogr D Biol Crystallogr 2015 Jan 1;71(Pt 1):127-35. Epub 2015 Jan 1.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, England.

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http://dx.doi.org/10.1107/S1399004714025280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304693PMC
January 2015

Automated structural comparisons clarify the phylogeny of the right-hand-shaped polymerases.

Mol Biol Evol 2014 Oct 24;31(10):2741-52. Epub 2014 Jul 24.

Department of Biosciences, Viikki Biocenter, University of Helsinki, Helsinki, Finland

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http://dx.doi.org/10.1093/molbev/msu219DOI Listing
October 2014

New methods for indexing multi-lattice diffraction data.

Acta Crystallogr D Biol Crystallogr 2014 Oct 27;70(Pt 10):2652-66. Epub 2014 Sep 27.

Diamond Light Source Ltd, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.

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http://dx.doi.org/10.1107/S1399004714017039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188007PMC
October 2014

Unexpected structure for the N-terminal domain of hepatitis C virus envelope glycoprotein E1.

Nat Commun 2014 Sep 16;5:4874. Epub 2014 Sep 16.

1] Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, UK [2] Diamond Light Source Limited, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.

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http://dx.doi.org/10.1038/ncomms5874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175578PMC
September 2014

Pushing the limits of sulfur SAD phasing: de novo structure solution of the N-terminal domain of the ectodomain of HCV E1.

Acta Crystallogr D Biol Crystallogr 2014 Aug 25;70(Pt 8):2197-203. Epub 2014 Jul 25.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, England.

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http://dx.doi.org/10.1107/S139900471401339XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118829PMC
August 2014

Combined approaches to study virus structures.

Subcell Biochem 2013 ;68:203-46

Structural Biology Unit, CICbioGUNE, CIBERehd, Bizkaia Technology Park, 48160, Derio, Spain.

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http://dx.doi.org/10.1007/978-94-007-6552-8_7DOI Listing
July 2014

Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor.

Nat Commun 2014 Jul 14;5:4321. Epub 2014 Jul 14.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1038/ncomms5321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104448PMC
July 2014

Exploiting fast detectors to enter a new dimension in room-temperature crystallography.

Acta Crystallogr D Biol Crystallogr 2014 May 26;70(Pt 5):1248-56. Epub 2014 Apr 26.

Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.

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http://dx.doi.org/10.1107/S1399004714005379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014120PMC
May 2014

In cellulo structure determination of a novel cypovirus polyhedrin.

Acta Crystallogr D Biol Crystallogr 2014 May 30;70(Pt 5):1435-41. Epub 2014 Apr 30.

Division of Structural Biology, The Welcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, England.

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http://dx.doi.org/10.1107/S1399004714004714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014125PMC
May 2014

Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution.

Nucleic Acids Res 2013 Nov 11;41(20):9396-410. Epub 2013 Aug 11.

Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, UK, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, 00290 Helsinki, Finland, Department of Environmental Research, Siauliai University, Vilniaus gatvė 88, 76285 Siauliai, Lithuania, Diamond Light Source Limited, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, UK, Department of Biosciences, University of Helsinki, Biocenter 2, PO Box 56, 00014 Helsinki, Finland, Institute of Biotechnology, University of Helsinki, Biocenter 2, PO Box 56, 00014 Helsinki, Finland and Astbury Centre for Structural Molecular Biology and School of Cellular and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.

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http://dx.doi.org/10.1093/nar/gkt713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814363PMC
November 2013

From lows to highs: using low-resolution models to phase X-ray data.

Acta Crystallogr D Biol Crystallogr 2013 Nov 18;69(Pt 11):2257-65. Epub 2013 Oct 18.

Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, England.

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http://journals.iucr.org/d/issues/2013/11/00/ba5207/ba5207.p
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http://scripts.iucr.org/cgi-bin/paper?S0907444913022336
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http://dx.doi.org/10.1107/S0907444913022336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817700PMC
November 2013

Binding of (5S)-penicilloic acid to penicillin binding protein 3.

ACS Chem Biol 2013 Oct 15;8(10):2112-6. Epub 2013 Aug 15.

Chemistry Research Laboratory, University of Oxford , 12 Mansfield Road, Oxford OX1 3TA, U.K.

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http://dx.doi.org/10.1021/cb400200hDOI Listing
October 2013

Plate tectonics of virus shell assembly and reorganization in phage φ8, a distant relative of mammalian reoviruses.

Structure 2013 Aug 25;21(8):1384-95. Epub 2013 Jul 25.

Division of Structural Biology, The Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1016/j.str.2013.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737474PMC
August 2013

Automatic comparison and classification of protein structures.

J Struct Biol 2013 Jul 21;183(1):47-56. Epub 2013 May 21.

Institute of Biotechnology and Department of Biosciences, University of Helsinki, Finland.

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http://dx.doi.org/10.1016/j.jsb.2013.05.007DOI Listing
July 2013

Bacteriophage P23-77 capsid protein structures reveal the archetype of an ancient branch from a major virus lineage.

Structure 2013 May 25;21(5):718-26. Epub 2013 Apr 25.

Department of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, Jyväskylä 40014, Finland.

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http://dx.doi.org/10.1016/j.str.2013.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919167PMC
May 2013

Structure determination from a single high-pressure-frozen virus crystal.

Acta Crystallogr D Biol Crystallogr 2013 Feb 19;69(Pt 2):308-12. Epub 2013 Jan 19.

Deutsches Elektronen-Synchrotron (DESY), Notkestrasse 85, 22607 Hamburg, Germany.

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http://scripts.iucr.org/cgi-bin/paper?S090744491204543X
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http://dx.doi.org/10.1107/S090744491204543XDOI Listing
February 2013

Antigenic switching of hepatitis B virus by alternative dimerization of the capsid protein.

Structure 2013 Jan 6;21(1):133-142. Epub 2012 Dec 6.

Protein Expression Laboratory, National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.str.2012.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544974PMC
January 2013

Structure of a pestivirus envelope glycoprotein E2 clarifies its role in cell entry.

Cell Rep 2013 Jan 27;3(1):30-5. Epub 2012 Dec 27.

Division of Structural Biology, The Wellcome Trust Center for Human Genetics, University of Oxford, Headington, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1016/j.celrep.2012.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607223PMC
January 2013

Expression, purification and crystallization of the ectodomain of the envelope glycoprotein E2 from Bovine viral diarrhoea virus.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 Jan 15;69(Pt 1):35-8. Epub 2012 Dec 15.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, England.

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January 2013

Louise N. Johnson 1940-2012.

Nat Struct Mol Biol 2012 Dec;19(12):1216-7

Institute of Cancer Research, Chester Beatty Laboratories, London, UK.

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December 2012

Dame Louise Napier Johnson (1940-2012).

J Synchrotron Radiat 2012 Nov 23;19(Pt 6):1061-3. Epub 2012 Oct 23.

Department of Chemistry, University of York, Heslington, York, UK.

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November 2012

A plate-based high-throughput assay for virus stability and vaccine formulation.

J Virol Methods 2012 Oct 26;185(1):166-70. Epub 2012 Jun 26.

Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN, UK.

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October 2012

The C-terminal priming domain is strongly associated with the main body of bacteriophage ϕ6 RNA-dependent RNA polymerase.

Virology 2012 Oct 6;432(1):184-93. Epub 2012 Jul 6.

Department of Biosciences, University of Helsinki, Biocenter 2, 00014 University of Helsinki, Finland.

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October 2012

Chemical and structural analysis of an antibody folding intermediate trapped during glycan biosynthesis.

J Am Chem Soc 2012 Oct 15;134(42):17554-63. Epub 2012 Oct 15.

Division of Structural Biology, University of Oxford, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, United Kingdom.

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October 2012

Structure unifies the viral universe.

Annu Rev Biochem 2012 5;81:795-822. Epub 2012 Apr 5.

Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio, Spain.

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August 2012

Structure of the regulatory domain of the LysR family regulator NMB2055 (MetR-like protein) from Neisseria meningitidis.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Jul 22;68(Pt 7):730-7. Epub 2012 Jun 22.

Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, England.

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July 2012

Outrunning free radicals in room-temperature macromolecular crystallography.

Acta Crystallogr D Biol Crystallogr 2012 Jul 15;68(Pt 7):810-8. Epub 2012 Jun 15.

Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, England.

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July 2012

In situ macromolecular crystallography using microbeams.

Acta Crystallogr D Biol Crystallogr 2012 May 17;68(Pt 5):592-600. Epub 2012 Apr 17.

Life Science Division, Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, England.

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May 2012

Crystallization and preliminary crystallographic analysis of the major capsid proteins VP16 and VP17 of bacteriophage P23-77.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 May 21;68(Pt 5):580-3. Epub 2012 Apr 21.

Department of Biological and Environmental Science and Nanoscience Center, University of Jyväskylä, PO Box 35, 40014 University of Jyväskylä, Finland.

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May 2012

Noncatalytic ions direct the RNA-dependent RNA polymerase of bacterial double-stranded RNA virus ϕ6 from de novo initiation to elongation.

J Virol 2012 Mar 28;86(5):2837-49. Epub 2011 Dec 28.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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March 2012

Insights into the evolution of a complex virus from the crystal structure of vaccinia virus D13.

Structure 2011 Jul;19(7):1011-20

The Division of Structural Biology and the Oxford Protein Production Facility, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.

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July 2011

Use of the α-mannosidase I inhibitor kifunensine allows the crystallization of apo CTLA-4 homodimer produced in long-term cultures of Chinese hamster ovary cells.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 Jul 30;67(Pt 7):785-9. Epub 2011 Jun 30.

Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, England.

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July 2011

The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

PLoS Pathog 2011 Jun 23;7(6):e1002085. Epub 2011 Jun 23.

Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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https://dx.plos.org/10.1371/journal.ppat.1002085
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June 2011