David I Rodenhiser

David I Rodenhiser

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David I Rodenhiser

David I Rodenhiser

Publications by authors named "David I Rodenhiser"

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26Publications

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Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues.

Front Oncol 2018 23;8:100. Epub 2018 Apr 23.

Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada.

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http://dx.doi.org/10.3389/fonc.2018.00100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925605PMC
April 2018

Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes.

Am J Hum Genet 2018 01;102(1):156-174

Department of Pathology and Laboratory Medicine, Western University, London, ON N6A5C1, Canada; Molecular Genetics Laboratory, Molecular Diagnostics Division, London Health Sciences Centre, London, ON N6A5W9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777983PMC
January 2018

DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.

Crit Rev Clin Lab Sci 2016 12;53(3):147-65. Epub 2016 Jan 12.

a Departments of Pathology and Laboratory Medicine .

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http://dx.doi.org/10.3109/10408363.2015.1113496DOI Listing
November 2016

Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.

J Mol Diagn 2016 11 29;18(6):834-841. Epub 2016 Aug 29.

Department of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada; London Regional Cancer Program, London Health Sciences Center, London, Ontario, Canada; Children's Health Research Institute, London Health Sciences Center, London, Ontario, Canada; Molecular Genetics Laboratory, London Health Sciences Center, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.06.005DOI Listing
November 2016

Epigenetics, eh! A meeting summary of the Canadian Conference on Epigenetics.

Epigenetics 2011 Oct 1;6(10):1265-71. Epub 2011 Oct 1.

EpiGenwestern Research Group, Children's Health Research Institute, and Department of Biochemistry, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.4161/epi.6.10.17491DOI Listing
October 2011

Gene signatures of breast cancer progression and metastasis.

Breast Cancer Res 2011 Jan 24;13(1):201. Epub 2011 Jan 24.

London Regional Cancer Program, Cancer Research Laboratories, London Health Sciences Centre, 790 Commissioners Road East, London, Ontario, N6A 4L6, Canada.

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http://dx.doi.org/10.1186/bcr2791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109557PMC
January 2011

Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays.

Breast Cancer Res 2008 18;10(4):R62. Epub 2008 Jul 18.

London Regional Cancer Program, Victoria Research Laboratories, London Health Sciences Centre, 790 Commissioners Road East, London, Ontario, N6A 4L6, Canada.

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http://dx.doi.org/10.1186/bcr2121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575535PMC
April 2009

Epigenetic contributions to cancer metastasis.

Clin Exp Metastasis 2009 2;26(1):5-18. Epub 2008 Apr 2.

Departments of Biochemistry, Oncology and Paediatrics, University of Western Ontario, London, Ontario, Canada.

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http://link.springer.com/content/pdf/10.1007/s10585-008-9166
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http://link.springer.com/10.1007/s10585-008-9166-2
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http://dx.doi.org/10.1007/s10585-008-9166-2DOI Listing
February 2009

New clinical and experimental approaches for studying tumor dormancy: does tumor dormancy offer a therapeutic target?

APMIS 2008 Jul-Aug;116(7-8):552-68

Massachusetts General Hospital Cancer Center, and Department of Medicine, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/j.1600-0463.2008.001059.xDOI Listing
November 2008

Distinct karyotypes in three breast cancer cell lines --21PTCi, 21NTCi, and 21MT-1 --derived from the same patient and representing different stages of tumor progression.

Cancer Genet Cytogenet 2008 Oct;186(1):33-40

Cytogenetics Laboratory, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cancergencyto.2008.05.012DOI Listing
October 2008

Genome-wide H3K9 histone acetylation profiles are altered in benzopyrene-treated MCF7 breast cancer cells.

J Biol Chem 2008 Feb 7;283(7):4051-60. Epub 2007 Dec 7.

London Regional Cancer Program, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M707506200
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http://dx.doi.org/10.1074/jbc.M707506200DOI Listing
February 2008

Molecular cytogenetic characterization of human breast cancer cell line MDA-MB-468 and its variant 468LN, which displays aggressive lymphatic metastasis.

Cancer Genet Cytogenet 2008 Feb;181(1):1-7

Cytogenetics Laboratory, London Health Sciences Centre, University of Western Ontario, 375 South Street, Room N258, London, Ontario N6A 4G5, Canada.

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http://dx.doi.org/10.1016/j.cancergencyto.2007.05.030DOI Listing
February 2008

DNA methylation analysis using CpG microarrays is impaired in benzopyrene exposed cells.

Toxicol Appl Pharmacol 2007 Dec 23;225(3):300-9. Epub 2007 Aug 23.

Department of Biochemistry, University of Western Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S0041008X0700374
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http://dx.doi.org/10.1016/j.taap.2007.08.013DOI Listing
December 2007

Epigenetic inactivation of BRCA1 is associated with aberrant expression of CTCF and DNA methyltransferase (DNMT3B) in some sporadic breast tumours.

Eur J Cancer 2007 Jan 27;43(1):210-9. Epub 2006 Oct 27.

The University of Western Ontario and the London Regional Cancer Program, London Health Sciences Centre, Room A4-134, 790 Commissioners Rd. East, London, Ont., Canada N6A 4L6.

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http://linkinghub.elsevier.com/retrieve/pii/S095980490600800
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http://dx.doi.org/10.1016/j.ejca.2006.09.002DOI Listing
January 2007

Benzopyrene exposure disrupts DNA methylation and growth dynamics in breast cancer cells.

Toxicol Appl Pharmacol 2006 Nov 30;216(3):458-68. Epub 2006 Jun 30.

Department of Biochemistry, University of Western Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S0041008X0600203
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http://dx.doi.org/10.1016/j.taap.2006.06.012DOI Listing
November 2006

Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites.

Breast Cancer Res 2004 30;6(4):R329-37. Epub 2004 Apr 30.

The London Regional Cancer Centre, Child Health Research Institute, and the Department of Biochemistry, Paediatrics and Oncology, at the University of Western Ontario, London, Ontario, Canada.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC468641PMC
November 2004

DNA binding sites for putative methylation boundaries in the unmethylated region of the BRCA1 promoter.

Int J Cancer 2004 Sep;111(5):669-78

London Regional Cancer Centre, Child Health Research Institute, London, Ontario, Canada.

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http://dx.doi.org/10.1002/ijc.20324DOI Listing
September 2004

Characterization of functional elements in the neurofibromatosis (NF1) proximal promoter region.

Oncogene 2004 Jan;23(2):330-9

London Regional Cancer Centre, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1038/sj.onc.1207053DOI Listing
January 2004