David Hovda

David Hovda

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David Hovda

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Bridging the gap: Mechanisms of plasticity and repair after pediatric TBI.

Exp Neurol 2019 08 2;318:78-91. Epub 2019 May 2.

UCLA Brain Injury Research Center, Department of Neurosurgery, University of California at Los Angeles, Box 956901, 300 Stein Plaza, Ste 562, 5th Floor, Los Angeles, CA 90095-6901, United States of America; Steve Tisch BrainSPORT Program, University of California at Los Angeles, Los Angeles, CA, United States of America; Division of Pediatric Neurology, Mattel Children's Hospital - UCLA, Los Angeles, CA, United States of America. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144886193008
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http://dx.doi.org/10.1016/j.expneurol.2019.04.016DOI Listing
August 2019

Acute glucose and lactate metabolism are associated with cognitive recovery following traumatic brain injury.

J Neurosci Res 2018 04 13;96(4):696-701. Epub 2017 Jun 13.

University of California, Los Angeles, Department of Psychiatry and Biobehavioral Sciences.

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http://dx.doi.org/10.1002/jnr.24097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729060PMC
April 2018

New astroglial injury-defined biomarkers for neurotrauma assessment.

J Cereb Blood Flow Metab 2017 Oct 17;37(10):3278-3299. Epub 2017 Aug 17.

1 Semel Institute for Neuroscience and Human Behavior, 12222 University of California , Los Angeles, CA, USA.

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http://dx.doi.org/10.1177/0271678X17724681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624401PMC
October 2017

It's Not All Fun and Games: Sports, Concussions, and Neuroscience.

Neuron 2017 Jun;94(6):1051-1055

UCLA Brain Injury Research Center, UCLA Steve Tisch BrainSPORT Program, Department of Neurosurgery, David Geffen School of Medicine, Los Angeles, CA 90095, USA; Interdepartmental Program for Neuroscience, UCLA, Los Angeles, CA 90095, USA; Interdepartmental Program for Biomedical Engineering, UCLA, Los Angeles, CA 90095, USA; Department of Medical and Molecular Pharmacology, David Geffen School of Medicine, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.neuron.2017.05.003DOI Listing
June 2017

Influence of Glycemic Control on Endogenous Circulating Ketone Concentrations in Adults Following Traumatic Brain Injury.

Neurocrit Care 2017 04;26(2):239-246

Department of Neurosurgery, UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, University of California - Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s12028-016-0313-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336412PMC
April 2017

Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity.

J Cereb Blood Flow Metab 2016 09 13;36(9):1603-13. Epub 2015 Oct 13.

Department of Neurosurgery, Los Angeles, CA, USA The UCLA Brain Injury Research Center, Los Angeles, CA, USA The Interdepartmental Program for Neuroscience, Los Angeles, CA, USA.

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http://dx.doi.org/10.1177/0271678X15610584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012517PMC
September 2016

Cellular and molecular neuronal plasticity.

Handb Clin Neurol 2015 ;128:681-90

Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/B978-0-444-63521-1.00042-XDOI Listing
August 2016

Collaborative approach leads to leaps in traumatic brain injury treatment.

Authors:
David Hovda

Mod Healthc 2016 Aug;45(27):25

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August 2016

Pyruvate treatment attenuates cerebral metabolic depression and neuronal loss after experimental traumatic brain injury.

Brain Res 2016 07 6;1642:270-277. Epub 2016 Apr 6.

UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-6901, USA; Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-6901, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2016.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899222PMC
July 2016

The Molecular Pathophysiology of Concussive Brain Injury - an Update.

Phys Med Rehabil Clin N Am 2016 05;27(2):373-93

Interdepartmental Programs for Neuroscience and Biomedical Engineering, Department of Neurosurgery, UCLA Brain Injury Research Center, Semel Institute, David Geffen School of Medicine at UCLA, Mattel Children's Hospital - UCLA, Room 18-218B, 10833 Le Conte Boulevard, Los Angeles, CA 90095, USA; Interdepartmental Programs for Neuroscience and Biomedical Engineering, Division of Pediatric Neurology, Department of Pediatrics, UCLA Brain Injury Research Center, Semel Institute, David Geffen School of Medicine at UCLA, Mattel Children's Hospital - UCLA, Room 18-218B, 10833 Le Conte Boulevard, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.pmr.2016.01.003DOI Listing
May 2016

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury.

Brain Inform 2016 Mar 1;3(1):1-15. Epub 2015 Dec 1.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://link.springer.com/10.1007/s40708-015-0026-y
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http://dx.doi.org/10.1007/s40708-015-0026-yDOI Listing
March 2016

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury.

Brain Inform 2016;3:1-15. Epub 2015 Dec 1.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA USA ; Department of Biomathematics, David Geffen School of Medicine at UCLA, Los Angeles, CA USA.

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http://link.springer.com/10.1007/s40708-015-0026-y
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http://dx.doi.org/10.1007/s40708-015-0026-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769312PMC
December 2015

Glucose administration after traumatic brain injury exerts some benefits and no adverse effects on behavioral and histological outcomes.

Brain Res 2015 Jul 21;1614:94-104. Epub 2015 Apr 21.

UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-6901, USA; Department of Neurosurgery, David Geffen School of Medicine at UCLA, 300 Stein Plaza, Ste. 562, Box 956901, Los Angeles, CA 90095-6901, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457685PMC
July 2015

Lactate: brain fuel in human traumatic brain injury: a comparison with normal healthy control subjects.

J Neurotrauma 2015 Jun 31;32(11):820-32. Epub 2015 Mar 31.

3Department of Integrative Biology, University of California, Berkeley, California.

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http://dx.doi.org/10.1089/neu.2014.3483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530406PMC
June 2015

The neurophysiology of concussion.

Authors:
David A Hovda

Prog Neurol Surg 2014 6;28:28-37. Epub 2014 Jun 6.

Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, Calif., USA.

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http://dx.doi.org/10.1159/000358749DOI Listing
February 2015

Adolescent TBI-induced hypopituitarism causes sexual dysfunction in adult male rats.

Dev Neurobiol 2015 Feb 1;75(2):193-202. Epub 2014 Aug 1.

Department of Neurosurgery, Semel Institute, Los Angeles, California, 90095; The UCLA Brain Injury Research Center, Semel Institute, Los Angeles, California, 90095.

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http://dx.doi.org/10.1002/dneu.22218DOI Listing
February 2015

The new neurometabolic cascade of concussion.

Neurosurgery 2014 Oct;75 Suppl 4:S24-33

*Division of Pediatric Neurology, Department of Pediatrics, Mattel Children's Hospital-UCLA, Los Angeles, California; ‡Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California; §Interdepartmental Programs for Neuroscience and Biomedical Engineering, UCLA, Los Angeles, California; ¶Department of Medical and Molecular Pharmacology, UCLA, Los Angeles, California.

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https://academic.oup.com/neurosurgery/article-lookup/doi/10.
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http://dx.doi.org/10.1227/NEU.0000000000000505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479139PMC
October 2014

Amnesia for early life stress does not preclude the adult development of posttraumatic stress disorder symptoms in rats.

Biol Psychiatry 2014 Aug 12;76(4):306-14. Epub 2013 Oct 12.

Department of Psychology, Brain Research Institute, Los Angeles, Los Angeles, California; UCLA Behavioral Testing Core, Brain Research Institute, Los Angeles, Los Angeles, California; Department of Psychiatry and Biobehavioral Sciences, UCLA Integrative Center for Learning and Memory, Los Angeles, Los Angeles, California; Department of Medical and Molecular Pharmacology, University of California, Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1016/j.biopsych.2013.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984614PMC
August 2014

Traumatic brain injury reveals novel cell lineage relationships within the subventricular zone.

Stem Cell Res 2014 Jul 28;13(1):48-60. Epub 2014 Apr 28.

The UCLA Brain Injury Research Center, Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2014.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096985PMC
July 2014

Recovery of stress response coincides with responsiveness to voluntary exercise after traumatic brain injury.

J Neurotrauma 2014 Apr 19;31(7):674-82. Epub 2013 Dec 19.

1 Department of Neurosurgery, David Geffen School of Medicine at UCLA , Los Angeles, California.

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http://dx.doi.org/10.1089/neu.2013.3151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961793PMC
April 2014

Sports-related concussion: ongoing debate.

Br J Sports Med 2014 Jan 15;48(2):75-6. Epub 2013 Mar 15.

Department of Kinesiology and Neurosurgery, Penn State Center for Sports Concussion, The Pennsylvania State University, Penn State Hershey Medical Center, , University Park, Pennsylvania, USA.

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http://dx.doi.org/10.1136/bjsports-2013-092362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511123PMC
January 2014

The effects of repeat traumatic brain injury on the pituitary in adolescent rats.

J Neurotrauma 2013 Dec 8;30(23):1983-90. Epub 2013 Oct 8.

1 Department of Neurosurgery, Semel Institute , Los Angeles, California.

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http://dx.doi.org/10.1089/neu.2013.2990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889497PMC
December 2013

Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction.

Neuroimage Clin 2012 24;1(1):1-17. Epub 2012 Aug 24.

Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.nicl.2012.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757727PMC
November 2013

Glucose administration after traumatic brain injury improves cerebral metabolism and reduces secondary neuronal injury.

Brain Res 2013 Oct 29;1535:124-36. Epub 2013 Aug 29.

UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-7039, USA; Department of Neurosurgery, David Geffen School of Medicine at UCLA, Box 957039, Los Angeles, CA 90095-7039, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2013.08.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857755PMC
October 2013

Early metabolic crisis-related brain atrophy and cognition in traumatic brain injury.

Brain Imaging Behav 2013 Sep;7(3):307-15

Los Angeles Biomedical Research Institute, Psychology Division, Department of Psychiatry, Harbor-University of California, Los Angeles Medical Center, 1124 W. Carson St., B-4 South (Box 490), Torrance, CA, 90502, USA,

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http://link.springer.com/10.1007/s11682-013-9231-6
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http://dx.doi.org/10.1007/s11682-013-9231-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172457PMC
September 2013

Potentially neuroprotective gene modulation in an in vitro model of mild traumatic brain injury.

Mol Cell Biochem 2013 Mar 15;375(1-2):185-98. Epub 2012 Dec 15.

Neuropharmacology and Neurobiology Section, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1007/s11010-012-1541-2DOI Listing
March 2013

Redefining the pericontusional penumbra following traumatic brain injury: evidence of deteriorating metabolic derangements based on positron emission tomography.

J Neurotrauma 2013 Mar;30(5):352-60

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-7039, USA.

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http://dx.doi.org/10.1089/neu.2012.2610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589887PMC
March 2013

Temperature and heart rate responses to exercise following mild traumatic brain injury.

J Neurotrauma 2013 Feb 4;30(4):281-91. Epub 2013 Feb 4.

Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-7039, USA.

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http://www.liebertpub.com/doi/10.1089/neu.2012.2616
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http://dx.doi.org/10.1089/neu.2012.2616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579384PMC
February 2013

Repeated mild traumatic brain injury: mechanisms of cerebral vulnerability.

J Neurotrauma 2013 Jan;30(1):30-8

Department of Neurosurgery, University of California, School of Medicine, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1089/neu.2012.2399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047842PMC
January 2013

A pediatric perspective on concussion pathophysiology.

Curr Opin Pediatr 2012 Dec;24(6):689-95

Department of Pediatrics, Division of Pediatric Neurology, David Geffen School of Medicine and Mattel Children's Hospital at UCLA, California 90095-1752, USA.

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http://dx.doi.org/10.1097/MOP.0b013e32835a1a44DOI Listing
December 2012

Concussive brain injury enhances fear learning and excitatory processes in the amygdala.

Biol Psychiatry 2012 Feb 9;71(4):335-43. Epub 2011 Dec 9.

UCLA Neurotrauma Laboratory, Department of Neurosurgery, David Geffen School of Medicine, University of California at Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.biopsych.2011.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264758PMC
February 2012

Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury.

J Neurotrauma 2011 Sep 4;28(9):1813-25. Epub 2011 Aug 4.

Department of Neurosurgery, UCLA David Geffen School of Medicine, Los Angeles, California, USA.

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http://dx.doi.org/10.1089/neu.2011.1822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172875PMC
September 2011

Pivotal role of anterior cingulate cortex in working memory after traumatic brain injury in youth.

Front Neurol 2011 21;1:158. Epub 2011 Jan 21.

Psychiatry and Biobehavioral Sciences, University of California Los Angeles David Geffen School of Medicine Los Angeles, CA, USA.

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http://dx.doi.org/10.3389/fneur.2010.00158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026484PMC
July 2011

Molecular and physiological responses to juvenile traumatic brain injury: focus on growth and metabolism.

Dev Neurosci 2010 12;32(5-6):431-41. Epub 2010 Nov 12.

Department of Psychiatry, David Geffen School of Medicine at UCLA, Los Angeles, Calif., USA.

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http://dx.doi.org/10.1159/000320667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215243PMC
May 2011

Delayed sodium pyruvate treatment improves working memory following experimental traumatic brain injury.

Neurosci Lett 2011 Mar 15;491(2):158-62. Epub 2011 Jan 15.

Department of Neurosurgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.neulet.2011.01.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045674PMC
March 2011

The molecular pathophysiology of concussive brain injury.

Clin Sports Med 2011 Jan;30(1):33-48, vii-iii

Department of Neurosurgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Boulevard, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.csm.2010.09.001DOI Listing
January 2011

Astrocyte oxidative metabolism and metabolite trafficking after fluid percussion brain injury in adult rats.

J Neurotrauma 2010 Dec 23;27(12):2191-202. Epub 2010 Nov 23.

Brain Injury Research Center, David Geffen School of Medicine at the University of California-Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1089/neu.2010.1508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996847PMC
December 2010

Chondroitinase ABC enhances pericontusion axonal sprouting but does not confer robust improvements in behavioral recovery.

J Neurotrauma 2010 Nov 20;27(11):1971-82. Epub 2010 Oct 20.

The University of California-Los Angeles (UCLA) Brain Injury Research Center, Los Angeles, California 90095-7039, USA.

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http://dx.doi.org/10.1089/neu.2010.1470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978059PMC
November 2010

Early nonischemic oxidative metabolic dysfunction leads to chronic brain atrophy in traumatic brain injury.

J Cereb Blood Flow Metab 2010 Apr 23;30(4):883-94. Epub 2009 Dec 23.

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1038/jcbfm.2009.263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949156PMC
April 2010

Pericontusion axon sprouting is spatially and temporally consistent with a growth-permissive environment after traumatic brain injury.

J Neuropathol Exp Neurol 2010 Feb;69(2):139-54

UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-7039, USA.

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http://dx.doi.org/10.1097/NEN.0b013e3181cb5beeDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821052PMC
February 2010

Ontogeny of Rat Recognition Memory measured by the novel object recognition task.

Dev Psychobiol 2009 Dec;51(8):672-8

Department of Neurosurgery, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1002/dev.20402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956740PMC
December 2009

Exercise-induced improvement in cognitive performance after traumatic brain injury in rats is dependent on BDNF activation.

Brain Res 2009 Sep 23;1288:105-15. Epub 2009 Jun 23.

Department of Neurosurgery, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095-7039, USA.

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http://dx.doi.org/10.1016/j.brainres.2009.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735616PMC
September 2009

The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats.

J Neurotrauma 2009 Jul;26(7):1083-93

Department of Neurosurgery, UCLA Brain Injury Research Center, Los Angeles, California 90095-7039, USA.

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http://dx.doi.org/10.1089/neu.2008.0769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843133PMC
July 2009

Metabolic and histologic effects of sodium pyruvate treatment in the rat after cortical contusion injury.

J Neurotrauma 2009 Jul;26(7):1095-110

Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-7039, USA.

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http://dx.doi.org/10.1089/neu.2008.0771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848946PMC
July 2009

Care of war veterans with mild traumatic brain injury.

N Engl J Med 2009 Jul;361(5):536-7; author reply 537-8

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http://dx.doi.org/10.1056/NEJMvcm0803922DOI Listing
July 2009

The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat.

J Neurotrauma 2009 Apr;26(4):497-506

Department of Neurosurgery, David Geffen School of Medicine, University of California at Los Angeles , Los Angeles, California 90095-7039, USA.

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http://dx.doi.org/10.1089/neu.2008.0664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843134PMC
April 2009

Controlled contusion injury alters molecular systems associated with cognitive performance.

J Neurosci Res 2009 Feb;87(3):795-805

Department of Neurosurgery, University of California, Los Angeles, California 90024-7039, USA.

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http://dx.doi.org/10.1002/jnr.21893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747484PMC
February 2009

Duration of ATP reduction affects extent of CA1 cell death in rat models of fluid percussion injury combined with secondary ischemia.

Brain Res 2008 Sep 9;1230:310-9. Epub 2008 Jul 9.

UCLA Brain Injury Research Center, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095-7039, USA.

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http://dx.doi.org/10.1016/j.brainres.2008.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581618PMC
September 2008

The impact of substance abuse on mortality in patients with severe traumatic brain injury.

J Trauma 2008 Sep;65(3):674-7

Queen's Medical Center Neuroscience Institute, Honolulu, Hawaii 96813, USA.

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http://dx.doi.org/10.1097/TA.0b013e31817db0a5DOI Listing
September 2008

Increased pentose phosphate pathway flux after clinical traumatic brain injury: a [1,2-13C2]glucose labeling study in humans.

J Cereb Blood Flow Metab 2007 Sep 7;27(9):1593-602. Epub 2007 Feb 7.

Division of Neurosurgery and Cerebral Blood Flow Laboratory, University of California at Los Angeles, Los Angeles, California 90095-7039, USA.

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http://dx.doi.org/10.1038/sj.jcbfm.9600458DOI Listing
September 2007

The fate of glucose during the period of decreased metabolism after fluid percussion injury: a 13C NMR study.

J Neurotrauma 2007 Jul;24(7):1079-92

UCLA Brain Injury Research Center, Division of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles California, USA.

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http://dx.doi.org/10.1089/neu.2006.0210DOI Listing
July 2007

Time window for voluntary exercise-induced increases in hippocampal neuroplasticity molecules after traumatic brain injury is severity dependent.

J Neurotrauma 2007 Jul;24(7):1161-71

Division of Neurosurgery, University of California-Los Angeles (UCLA), Los Angeles, California, USA.

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http://dx.doi.org/10.1089/neu.2006.0255DOI Listing
July 2007

Oxidative need and oxidative capacity following traumatic brain injury.

Authors:
David A Hovda

Crit Care Med 2007 Feb;35(2):663-4

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http://dx.doi.org/10.1097/01.CCM.0000254442.66789.52DOI Listing
February 2007

Glucose metabolism after traumatic brain injury: estimation of pyruvate carboxylase and pyruvate dehydrogenase flux by mass isotopomer analysis.

J Neurotrauma 2007 Jan;24(1):181-94

Brain Injury Research Center, Division of Neurosurgery, Department of Surgery and David Geffen School of Medicine at UCLA, University of California-Los Angeles, CA, USA.

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http://dx.doi.org/10.1089/neu.2006.0038DOI Listing
January 2007

Metabolic maturation of the brain: a study of local cerebral protein synthesis in the developing cat.

Brain Res 2006 Oct 24;1113(1):54-63. Epub 2006 Aug 24.

Department of Surgery, Division of Neurosurgery, UCLA, CA 90095-7039, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.07.083DOI Listing
October 2006

Traumatic brain injury induced neuroprotection of retinal ganglion cells to optic nerve crush.

J Neurotrauma 2006 Jul;23(7):1072-82

Jules Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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http://dx.doi.org/10.1089/neu.2006.23.1072DOI Listing
July 2006

N-methyl-D-aspartate receptor subunit changes after traumatic injury to the developing brain.

J Neurotrauma 2006 Jun;23(6):950-61

UCLA Brain Injury Research Center, Division of Neurosurgery/Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1089/neu.2006.23.950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531140PMC
June 2006

Functional outcome in TBI I: neuropsychological, emotional, and behavioral mediators.

J Clin Exp Neuropsychol 2006 May;28(4):567-80

Neuropsychology Division, Neuropsychiatric Institute and Hospital, UCLA, Los Angeles, CA 90024, USA.

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https://www.tandfonline.com/doi/full/10.1080/138033905004344
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http://dx.doi.org/10.1080/13803390500434466DOI Listing
May 2006

Functional outcome in TBI II: verbal memory and information processing speed mediators.

J Clin Exp Neuropsychol 2006 May;28(4):581-91

Neuropsychology Division, Neuropsychiatric Institute and Hospital, UCLA, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1080/13803390500434474DOI Listing
May 2006

Lateral fluid percussion injury in the developing rat causes an acute, mild behavioral dysfunction in the absence of significant cell death.

Brain Res 2006 Mar 20;1077(1):24-36. Epub 2006 Feb 20.

Division of Neurosurgery, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-7039, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.01.011DOI Listing
March 2006

Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury.

J Neurotrauma 2005 Oct;22(10):1052-65

Division of Neurosurgery, Department of Surgery, Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 92354, USA.

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http://dx.doi.org/10.1089/neu.2005.22.1052DOI Listing
October 2005

Routine and quantitative EEG in mild traumatic brain injury.

Clin Neurophysiol 2005 Sep;116(9):2001-25

Department of Neurology, University of California Los Angeles School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.clinph.2005.05.008DOI Listing
September 2005

Restoration of cerebral vasoreactivity by an L-type calcium channel blocker following fluid percussion brain injury.

J Neurotrauma 2005 Jul;22(7):763-71

Brain Injury Research Center, Department of Surgery/Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1089/neu.2005.22.763DOI Listing
July 2005

Experience-dependent behavioral plasticity is disturbed following traumatic injury to the immature brain.

Behav Brain Res 2005 Feb;157(1):11-22

Division of Neurosurgery, Department of Surgery, UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, Room 18-228 NPI, Mail Code 703919, Los Angeles, CA 90095, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016643280400224
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http://dx.doi.org/10.1016/j.bbr.2004.06.003DOI Listing
February 2005

Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis.

J Neurotrauma 2005 Jan;22(1):3-41

Division of Neurosurgery, Department of Surgery, The David Geffen UCLA School of Medicine, Los Angeles, California, USA.

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http://www.liebertpub.com/doi/10.1089/neu.2005.22.3
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http://dx.doi.org/10.1089/neu.2005.22.3DOI Listing
January 2005

Lateral fluid percussion brain injury: a 15-year review and evaluation.

J Neurotrauma 2005 Jan;22(1):42-75

Traumatic Brain Injury Laboratory, Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1089/neu.2005.22.42DOI Listing
January 2005

Subcortical white matter metabolic changes remote from focal hemorrhagic lesions suggest diffuse injury after human traumatic brain injury.

Neurosurgery 2004 Dec;55(6):1306-15; discussio 1316-7

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095-6901, USA.

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http://dx.doi.org/10.1227/01.neu.0000143028.08719.42DOI Listing
December 2004

Differential gene expression in hippocampus following experimental brain trauma reveals distinct features of moderate and severe injuries.

J Neurotrauma 2004 Sep;21(9):1141-53

Division of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-7039, USA.

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http://dx.doi.org/10.1089/neu.2004.21.1141DOI Listing
September 2004

Mitochondrial damage and dysfunction in traumatic brain injury.

Mitochondrion 2004 Sep;4(5-6):705-13

Traumatic Brain Injury Laboratory, Department of Neurosurgery, University of Pennsylvania, 5 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.mito.2004.07.021DOI Listing
September 2004

The upregulation of plasticity-related proteins following TBI is disrupted with acute voluntary exercise.

Brain Res 2004 Aug;1016(2):154-62

Division of Neurosurgery, Department of Surgery, UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.brainres.2004.04.079DOI Listing
August 2004

Accuracy of a method using short inhalation of (15)O-O(2) for measuring cerebral oxygen extraction fraction with PET in healthy humans.

J Nucl Med 2004 May;45(5):765-70

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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May 2004

Acute changes in regional cerebral (18)F-FDG kinetics in patients with traumatic brain injury.

J Nucl Med 2004 May;45(5):775-83

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095-6948, USA.

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May 2004

Paradoxical effects of cortical impact injury on environmentally enriched rats.

J Neurotrauma 2004 May;21(5):513-9

Brain Injury Research Center, Department of Surgery (Neurosurgery), UCLA School of Medicine, Los Angeles, California, USA.

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http://dx.doi.org/10.1089/089771504774129856DOI Listing
May 2004

Regional heterogeneity of post-traumatic brain metabolism as studied by microdialysis, magnetic resonance spectroscopy and positron emission tomography.

Brain Pathol 2004 Apr;14(2):210-4

UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, CHS 18-218, Mail code 713909, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1111/j.1750-3639.2004.tb00055.xDOI Listing
April 2004

Selective metabolic reduction in gray matter acutely following human traumatic brain injury.

J Neurotrauma 2004 Feb;21(2):149-61

Department of Molecular and Medical Pharmacology, UCLA Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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http://dx.doi.org/10.1089/089771504322778613DOI Listing
February 2004

Correlation of regional metabolic rates of glucose with glasgow coma scale after traumatic brain injury.

J Nucl Med 2003 Nov;44(11):1709-16

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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November 2003

Metabolic, neurochemical, and histologic responses to vibrissa motor cortex stimulation after traumatic brain injury.

J Cereb Blood Flow Metab 2003 Aug;23(8):900-10

Division of Neurosurgery, Neuroscience Interdepartmental Ph.D. Program, University of California at Los Angeles, Los Angeles, California 90095, U.S.A.

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http://dx.doi.org/10.1097/01.WCB.0000076702.71231.F2DOI Listing
August 2003

Increased hippocampal CA3 vulnerability to low-level kainic acid following lateral fluid percussion injury.

J Neurotrauma 2003 May;20(5):409-20

Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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http://dx.doi.org/10.1089/089771503765355496DOI Listing
May 2003

The Neurometabolic Cascade of Concussion.

J Athl Train 2001 Sep;36(3):228-235

Neurotrauma Laboratory, Division of Neurosurgery, University of California, Los Angeles School of Medicine, Los Angeles, CA.

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http://www.sportsconcussion.co.za/Research/Pathophysiology/G
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155411PMC
September 2001