David Hot

David Hot

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David Hot

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A complete protocol for whole-genome sequencing of virus from clinical samples: Application to coronavirus OC43.

Virology 2019 05 9;531:141-148. Epub 2019 Mar 9.

Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR8204 - CIIL - Center for Infection and Immunity of Lille, F-59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2019.03.006DOI Listing
May 2019

Signal transduction-dependent small regulatory RNA is involved in glutamate metabolism of the human pathogen .

RNA 2018 11 10;24(11):1530-1541. Epub 2018 Aug 10.

Institute of Microbiology v.v.i., Laboratory of post-transcriptional control of gene expression, 14220 Prague, Czech Republic.

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http://rnajournal.cshlp.org/lookup/doi/10.1261/rna.067306.11
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http://dx.doi.org/10.1261/rna.067306.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191719PMC
November 2018

Chronic ingestion of deoxynivalenol at human dietary levels impairs intestinal homeostasis and gut microbiota in mice.

Arch Toxicol 2018 07 26;92(7):2327-2338. Epub 2018 May 26.

Univ. Lille, Inserm, CHU Lille, U995-LIRIC-Lille Inflammation Research International Center, 59000, Lille, France.

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http://dx.doi.org/10.1007/s00204-018-2228-6DOI Listing
July 2018

[Prospects for applications in human health of nanopore-based sequencing].

Med Sci (Paris) 2018 Apr 16;34(4):319-325. Epub 2018 Apr 16.

Univ Lille, CNRS, Inserm, CHU de Lille, Institut Pasteur de Lille, U1019-UMR 8204-CIIL-Centre d'Infection et d'Immunité de Lille, 1, rue du professeur Calmette, F-59000 Lille, France - Pegase-Biosciences, Institut Pasteur de Lille, 1, rue du professeur Calmette, 59019 Lille, France.

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http://dx.doi.org/10.1051/medsci/20183404012DOI Listing
April 2018

MICRA: an automatic pipeline for fast characterization of microbial genomes from high-throughput sequencing data.

Genome Biol 2017 12 19;18(1):233. Epub 2017 Dec 19.

University of Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019-UMR 8204-CIIL-Centre d'Infection et d'Immunité de Lille, F-59000, Lille, France.

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http://dx.doi.org/10.1186/s13059-017-1367-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738152PMC
December 2017

Characterization of a Bvg-regulated fatty acid methyl-transferase in Bordetella pertussis.

PLoS One 2017 11;12(5):e0176396. Epub 2017 May 11.

Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019- UMR 8204-CIIL-Centre d'Infection et d'Immunité de Lille, Lille, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176396PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426589PMC
September 2017

Assessment of Common and Emerging Bioinformatics Pipelines for Targeted Metagenomics.

PLoS One 2017 4;12(1):e0169563. Epub 2017 Jan 4.

Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 - UMR 8204 - CIIL - Centre d'Infection et d'Immunité de Lille, Lille, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169563PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215245PMC
August 2017

The multifaceted RisA regulon of Bordetella pertussis.

Sci Rep 2016 09 13;6:32774. Epub 2016 Sep 13.

Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.

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http://dx.doi.org/10.1038/srep32774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020355PMC
September 2016

Evidence for a role of the polysaccharide capsule transport proteins in pertussis pathogenesis.

PLoS One 2014 12;9(12):e115243. Epub 2014 Dec 12.

Department of Microbiology, Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Life Science #03-05, 28 Medical Drive, Singapore 117597, Singapore.

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https://pdfs.semanticscholar.org/8eb7/0dc9c3f5555f88b7850695
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http://dx.plos.org/10.1371/journal.pone.0115243
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115243PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264864PMC
March 2016

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract.

Vaccine 2015 Jun 21;33(29):3331-41. Epub 2015 May 21.

Institut Pasteur de Lille, Centre d'Infection et d'Immunité de Lille, F-59019 Lille, France; Institut National de la Santé et de la Recherche Médicale, U1019, F-59019 Lille, France; Centre National de la Recherche Scientifique, UMR 8204, F-59019 Lille, France; Université de Lille, F-59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.05.022DOI Listing
June 2015

Photodynamic therapy relieves colitis and prevents colitis-associated carcinogenesis in mice.

Inflamm Bowel Dis 2015 May;21(5):985-95

*Université de Lorraine, Centre de recherche en automatique de Nancy, Vandoeuvre-lès-Nancy, France; †Centre national de la recherche scientifique, Centre de recherche en automatique de Nancy, UMR7039, Vandœuvre-lès-Nancy, France; ‡Institut de Cancérologie de Lorraine, Vandoeuvre-lès-Nancy, France; §Institut National de la Santé et de la Recherche Médicale, U954, Vandoeuvre-lès-Nancy, France; ‖Gènes Diffusion, Douai, France; ¶Pegase-Biosciences, Institut Pasteur de Lille, Lille, France; and **Institut Pasteur de Lille, Centre d'Infection et d'Immunité de Lille, UMR1019, Lille, France.

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https://academic.oup.com/ibdjournal/article/21/5/985-995/457
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http://dx.doi.org/10.1097/MIB.0000000000000354DOI Listing
May 2015

Adventitial Tertiary Lymphoid Organs as Potential Source of MicroRNA Biomarkers for Abdominal Aortic Aneurysm.

Int J Mol Sci 2015 May 18;16(5):11276-93. Epub 2015 May 18.

National Institute of Health and Medical Research (INSERM) U1167, Lille Pasteur Institute, Lille North of France University, F-59000 Lille, France.

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http://dx.doi.org/10.3390/ijms160511276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463700PMC
May 2015

[High-throughput sequencing: towards a genome-based diagnosis in infectious diseases].

Med Sci (Paris) 2014 Dec 24;30(12):1144-51. Epub 2014 Dec 24.

FRE3642, Université de Lille, France - Pegase-Biosciences, Institut Pasteur de Lille, 1, rue du professeur Calmette, 59019 Lille, France.

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http://dx.doi.org/10.1051/medsci/20143012018DOI Listing
December 2014

Comparison of mapping algorithms used in high-throughput sequencing: application to Ion Torrent data.

BMC Genomics 2014 Apr 5;15:264. Epub 2014 Apr 5.

FRE 3642 Molecular and Cellular Medecine, CNRS, Institut Pasteur de Lille and Univ Lille Nord de France, Lille, France.

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http://dx.doi.org/10.1186/1471-2164-15-264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051166PMC
April 2014

High-Throughput Sequencing, a VersatileWeapon to Support Genome-Based Diagnosis in Infectious Diseases: Applications to Clinical Bacteriology.

Pathogens 2014 Apr 2;3(2):258-79. Epub 2014 Apr 2.

FRE 3642 Molecular and Cellular Medecine, CNRS, Institut Pasteur de Lille and University Lille Nord de France, Lille 59019, France.

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http://dx.doi.org/10.3390/pathogens3020258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243446PMC
April 2014

Transcriptomic insights into the oxidative response of stress-exposed Aspergillus fumigatus.

Curr Pharm Des 2013 ;19(20):3713-37

Biology and Diversity of Emerging Eukaryotic Pathogens (BDEEP), Inserm U1019-CNRS UMR 8204-Université Lille Nord de France, Institut Pasteur de Lille, Lille, France.

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http://dx.doi.org/10.2174/1381612811319200011DOI Listing
December 2013

The RNA chaperone Hfq is required for virulence of Bordetella pertussis.

Infect Immun 2013 Nov 26;81(11):4081-90. Epub 2013 Aug 26.

Institute of Microbiology, ASCR, v.v.i., Prague, Czech Republic.

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http://dx.doi.org/10.1128/IAI.00345-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811842PMC
November 2013

Toxoplasma transcription factor TgAP2XI-5 regulates the expression of genes involved in parasite virulence and host invasion.

J Biol Chem 2013 Oct 10;288(43):31127-38. Epub 2013 Sep 10.

From the Center for Infection and Immunity of Lille, CNRS UMR 8204, INSERM 1019, Université Lille Nord de France, Institut Pasteur de Lille, 59 000 Lille, France.

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http://dx.doi.org/10.1074/jbc.M113.486589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829425PMC
October 2013

Toxoplasma gondii Alba proteins are involved in translational control of gene expression.

J Mol Biol 2013 Apr 21;425(8):1287-301. Epub 2013 Feb 21.

Center for Infection and Immunity of Lille, CNRS UMR 8204, INSERM 1019, Université Lille Nord de France, Institut Pasteur de Lille, Lille, France.

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http://dx.doi.org/10.1016/j.jmb.2013.01.039DOI Listing
April 2013

The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation.

Mol Microbiol 2013 Feb 26;87(3):641-55. Epub 2012 Dec 26.

Center for Infection and Immunity of Lille, UMR CNRS 8204, INSERM U 1019, Institut Pasteur de Lille, Université Lille Nord de France, Lille, France.

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http://dx.doi.org/10.1111/mmi.12121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556193PMC
February 2013

Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.

PLoS One 2012 17;7(5):e36964. Epub 2012 May 17.

Université Lyon 1, Univ Lyon, CNRS, FRE 3310 - Dysfonctionnement de l'Homéostasie Tissulaire et Ingénierie Thérapeutique, IBCP, Lyon, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036964PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355169PMC
January 2013

Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum.

J Biol Chem 2012 Oct 13;287(41):34432-44. Epub 2012 Jul 13.

Université Lille Nord de France, Université Lille1, Unité de Glycobiologie Structurale et Fonctionnelle, UGSF, IFR 147, France.

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http://dx.doi.org/10.1074/jbc.M112.378083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464548PMC
October 2012

Toxoplasma gondii chromodomain protein 1 binds to heterochromatin and colocalises with centromeres and telomeres at the nuclear periphery.

PLoS One 2012 9;7(3):e32671. Epub 2012 Mar 9.

Center for Infection and Immunity of Lillle, CNRS UMR 8204, INSERM U 1019, Université Lille Nord de France, Institut Pasteur de Lille, Lille, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032671PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302879PMC
August 2012

Gene profiling analysis reveals the contribution of CD24 and P2Y6R to the susceptibility of young rats to Plasmodium berghei infection.

Cell Microbiol 2011 May 16;13(5):752-63. Epub 2011 Feb 16.

Center for Infection and Immunity of Lille, Institut Pasteur de Lille, INSERM U1019, CNRS UMR8204, University Lille Nord de France, IFR 142, 1 rue du Professeur A. Calmette, 59019 Lille, France.

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http://dx.doi.org/10.1111/j.1462-5822.2011.01574.xDOI Listing
May 2011

Identification of novel genes potentially involved in somatic embryogenesis in chicory (Cichorium intybus L.).

BMC Plant Biol 2010 Jun 22;10:122. Epub 2010 Jun 22.

UMR USTL-INRA 1281, Stress Abiotiques et Différenciation des Végétaux cultivés, Université Lille1, Cité Scientifique SN2, F-59650 Villeneuve d'Ascq, France.

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http://bmcplantbiol.biomedcentral.com/articles/10.1186/1471-
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http://dx.doi.org/10.1186/1471-2229-10-122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017773PMC
June 2010

Genomic island excisions in Bordetella petrii.

BMC Microbiol 2009 Jul 18;9:141. Epub 2009 Jul 18.

Lehrstuhl für Mikrobiologie, Biozentrum, Universität Würzburg, Am Hubland, Würzburg, Germany.

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http://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-
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http://dx.doi.org/10.1186/1471-2180-9-141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717098PMC
July 2009

Contribution of T cells and neutrophils in protection of young susceptible rats from fatal experimental malaria.

J Immunol 2007 Feb;178(3):1713-22

Institut National de la Santé et de la Recherche Médicale Unité 547, Institut Pasteur de Lille, Lille, France.

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http://dx.doi.org/10.4049/jimmunol.178.3.1713DOI Listing
February 2007

Temporal analysis of French Bordetella pertussis isolates by comparative whole-genome hybridization.

Microbes Infect 2006 Jul 6;8(8):2228-35. Epub 2006 Jun 6.

Molecular Prevention and Therapy of Human Diseases Unit, Institut Pasteur, FRE-CNRS 2849, National Center of Reference of Whooping Cough and other Bordetelloses, 25 rue du Dr Roux, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1016/j.micinf.2006.04.014DOI Listing
July 2006

Preparation of alpha-Oxo semicarbazone oligonucleotide microarrays.

Curr Protoc Nucleic Acid Chem 2005 Jan;Chapter 12:Unit 12.6

Université de Lille 2, Lille, France.

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http://dx.doi.org/10.1002/0471142700.nc1206s19DOI Listing
January 2005

Transcriptomic analysis in the leech Theromyzon tessulatum: involvement of cystatin B in innate immunity.

Biochem J 2004 Jun;380(Pt 3):617-25

Laboratoire de Neuroimmunologie des Annélides, UMR CNRS 8017, SN3, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq, France.

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http://biochemj.org/lookup/doi/10.1042/bj20040478
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http://dx.doi.org/10.1042/BJ20040478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224237PMC
June 2004

Alpha-oxo semicarbazone peptide or oligodeoxynucleotide microarrays.

Bioconjug Chem 2003 Mar-Apr;14(2):430-9

UMR CNRS 8525, Biological Institute of Lille, 1 rue du Pr Calmette 59021 Lille France.

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http://dx.doi.org/10.1021/bc025571qDOI Listing
November 2003