David Heckerman

David Heckerman

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David Heckerman

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Ensembles of Lasso Screening Rules.

IEEE Trans Pattern Anal Mach Intell 2018 12 24;40(12):2841-2852. Epub 2017 Nov 24.

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http://dx.doi.org/10.1109/TPAMI.2017.2765321DOI Listing
December 2018

Publisher Correction: Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneum L.

Nat Genet 2018 12;50(12):1754

Fujian Agriculture and Forestry University and University of Illinois at Urbana-Champaign School of Integrative Biology Joint Center for Genomics and Biotechnology, National Sugarcane Engineering Technology Research Center, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Key Laboratory of Genetics, Breeding and Multiple Utilization of Corps, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou, China.

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http://www.nature.com/articles/s41588-018-0293-7
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http://dx.doi.org/10.1038/s41588-018-0293-7DOI Listing
December 2018

Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneum L.

Nat Genet 2018 11 8;50(11):1565-1573. Epub 2018 Oct 8.

Fujian Agriculture and Forestry University and University of Illinois at Urbana-Champaign School of Integrative Biology Joint Center for Genomics and Biotechnology, National Sugarcane Engineering Technology Research Center, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Key Laboratory of Genetics, Breeding and Multiple Utilization of Corps, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou, China.

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http://www.nature.com/articles/s41588-018-0237-2
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http://dx.doi.org/10.1038/s41588-018-0237-2DOI Listing
November 2018

Genetic variants associated with physical performance and anthropometry in old age: a genome-wide association study in the ilSIRENTE cohort.

Sci Rep 2017 Nov 20;7(1):15879. Epub 2017 Nov 20.

Center for Geriatric Medicine (CEMI), Department of Geriatrics, Neurosciences and Orthopedics, Catholic University of Sacred Heart, Rome, 00168, Italy.

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http://dx.doi.org/10.1038/s41598-017-13475-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696534PMC
November 2017

Linear mixed model for heritability estimation that explicitly addresses environmental variation.

Proc Natl Acad Sci U S A 2016 07;113(27):7377-82

Wellcome Trust Sanger Institute, Hinxton CB10 1SA, United Kingdom; Department of Medicine, University of Cambridge, Cambridge CB2 0SP, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1510497113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941438PMC
July 2016

Anti-hepatitis C virus T-cell immunity in the context of multiple exposures to the virus.

PLoS One 2015 24;10(6):e0130420. Epub 2015 Jun 24.

Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia; School of Medicine and Pharmacology, Harry Perkins Institute, University of Western Australia, Crawley, Western Australia, Australia; School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130420PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480353PMC
April 2016

Immune screening identifies novel T cell targets encoded by antisense reading frames of HIV-1.

J Virol 2015 Apr 14;89(7):4015-9. Epub 2015 Jan 14.

IrsiCaixa AIDS Research Institute-HIVACAT, Hospital Germans Trias I Pujol, Badalona, Spain Institucio Catalana de Recerca i Estudis Avancats (ICREA), Barcelona, Spain University of Vic and Central University of Catalonia, Vic, Catalonia, Spain Autonomous University of Barcelona, Barcelona, Catalonia, Spain

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http://dx.doi.org/10.1128/JVI.03435-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403399PMC
April 2015

Accurate liability estimation improves power in ascertained case-control studies.

Nat Methods 2015 Apr 9;12(4):332-4. Epub 2015 Feb 9.

eScience Group, Microsoft Research, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nmeth.3285DOI Listing
April 2015

ConPADE: genome assembly ploidy estimation from next-generation sequencing data.

PLoS Comput Biol 2015 Apr 16;11(4):e1004229. Epub 2015 Apr 16.

Microsoft Research, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400156PMC
April 2015

Greater power and computational efficiency for kernel-based association testing of sets of genetic variants.

Bioinformatics 2014 Nov 29;30(22):3206-14. Epub 2014 Jul 29.

eScience Research Group, Microsoft Research, Los Angeles, CA, 90024 and eScience Research Group, Microsoft Research, Redmond, WA, 98052, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221116PMC
November 2014

HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes.

J Virol 2014 Nov 27;88(22):12937-48. Epub 2014 Aug 27.

Ragon Institute of MGH, MIT and Harvard, Boston, Massachusetts, USA Howard Hughes Medical Institute, Chevy Chase, Maryland, USA

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http://dx.doi.org/10.1128/JVI.01004-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249072PMC
November 2014

Further improvements to linear mixed models for genome-wide association studies.

Sci Rep 2014 Nov 12;4:6874. Epub 2014 Nov 12.

eScience Group, Microsoft Research, 1100 Glendon Avenue, Suite PH1, Los Angeles, CA, 90024, United States.

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http://dx.doi.org/10.1038/srep06874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230738PMC
November 2014

Literome: PubMed-scale genomic knowledge base in the cloud.

Bioinformatics 2014 Oct 17;30(19):2840-2. Epub 2014 Jun 17.

Microsoft Research, One Microsoft Way, Redmond, WA 98052, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu383DOI Listing
October 2014

HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck.

Science 2014 Jul 10;345(6193):1254031. Epub 2014 Jul 10.

Emory Vaccine Center at Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA. Rwanda-Zambia HIV Research Group: Zambia-Emory HIV Research Project, Lusaka, Zambia. Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1126/science.1254031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289910PMC
July 2014

Quantifying the uncertainty in heritability.

J Hum Genet 2014 May 27;59(5):269-75. Epub 2014 Mar 27.

Microsoft Research, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/jhg.2014.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521294PMC
May 2014

Epigenome-wide association studies without the need for cell-type composition.

Nat Methods 2014 Mar 26;11(3):309-11. Epub 2014 Jan 26.

eScience Research Group, Microsoft Research, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nmeth.2815DOI Listing
March 2014

A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control.

Elife 2013 Oct 29;2:e01123. Epub 2013 Oct 29.

School of Life Sciences , École Polytechnique Fédérale de Lausanne , Lausanne , Switzerland ; Institute of Microbiology , University Hospital and University of Lausanne , Lausanne , Switzerland ; Research Group of Theoretical Biology and Evolutionary Ecology , Eötvös Loránd University and the Hungarian Academy of Sciences , Budapest , Hungary ; Swiss Institute of Bioinformatics , Lausanne , Switzerland.

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http://dx.doi.org/10.7554/eLife.01123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807812PMC
October 2013

A powerful and efficient set test for genetic markers that handles confounders.

Bioinformatics 2013 Jun 18;29(12):1526-33. Epub 2013 Apr 18.

eScience Group, Microsoft Research, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673214PMC
June 2013

Patterns of methylation heritability in a genome-wide analysis of four brain regions.

Nucleic Acids Res 2013 Feb 8;41(4):2095-104. Epub 2013 Jan 8.

eScience Group, Microsoft Research, 1100 Glendon Avenue, Suite PH1, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1093/nar/gks1449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575819PMC
February 2013

High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection.

Immunol Cell Biol 2012 Feb 17;90(2):224-34. Epub 2011 May 17.

Centre for Clinical Immunology and Biomedical Statistics, Institute for Immunology and Infectious Diseases, Murdoch University, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1038/icb.2011.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173576PMC
February 2012

Conditional random fields for fast, large-scale genome-wide association studies.

PLoS One 2011 12;6(7):e21591. Epub 2011 Jul 12.

Microsoft Research, Redmond, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021591PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134455PMC
November 2011

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.

Neuron 2011 Oct 21;72(2):257-68. Epub 2011 Sep 21.

Neuromuscular Diseases Research Unit, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.neuron.2011.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200438PMC
October 2011

Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes.

J Immunol 2011 Sep 5;187(5):2502-13. Epub 2011 Aug 5.

Centre for Clinical Immunology and Biomedical Statistics, Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia 6150, Australia.

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http://dx.doi.org/10.4049/jimmunol.1100691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183574PMC
September 2011

FaST linear mixed models for genome-wide association studies.

Nat Methods 2011 Sep 4;8(10):833-5. Epub 2011 Sep 4.

Microsoft Research, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nmeth.1681DOI Listing
September 2011

HIV-1 adaptation to NK-cell-mediated immune pressure.

Nature 2011 Aug 3;476(7358):96-100. Epub 2011 Aug 3.

Ragon Institute at MGH, MIT and Harvard, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129, USA.

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http://dx.doi.org/10.1038/nature10237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194000PMC
August 2011

Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape.

J Clin Invest 2011 Jun 9;121(6):2480-92. Epub 2011 May 9.

Ragon Institute of MGH, MIT and Harvard, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA.

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http://dx.doi.org/10.1172/JCI44932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104749PMC
June 2011

The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms.

J Virol 2011 Feb 24;85(3):1384-90. Epub 2010 Nov 24.

Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, South Parks Rd, Oxford OX1 3SY, United Kingdom.

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http://dx.doi.org/10.1128/JVI.01879-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020512PMC
February 2011

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

Authors:
Florencia Pereyra Xiaoming Jia Paul J McLaren Amalio Telenti Paul I W de Bakker Bruce D Walker Stephan Ripke Chanson J Brumme Sara L Pulit Mary Carrington Carl M Kadie Jonathan M Carlson David Heckerman Robert R Graham Robert M Plenge Steven G Deeks Lauren Gianniny Gabriel Crawford Jordan Sullivan Elena Gonzalez Leela Davies Amy Camargo Jamie M Moore Nicole Beattie Supriya Gupta Andrew Crenshaw Noël P Burtt Candace Guiducci Namrata Gupta Xiaojiang Gao Ying Qi Yuko Yuki Alicja Piechocka-Trocha Emily Cutrell Rachel Rosenberg Kristin L Moss Paul Lemay Jessica O'Leary Todd Schaefer Pranshu Verma Ildiko Toth Brian Block Brett Baker Alissa Rothchild Jeffrey Lian Jacqueline Proudfoot Donna Marie L Alvino Seanna Vine Marylyn M Addo Todd M Allen Marcus Altfeld Matthew R Henn Sylvie Le Gall Hendrik Streeck David W Haas Daniel R Kuritzkes Gregory K Robbins Robert W Shafer Roy M Gulick Cecilia M Shikuma Richard Haubrich Sharon Riddler Paul E Sax Eric S Daar Heather J Ribaudo Brian Agan Shanu Agarwal Richard L Ahern Brady L Allen Sherly Altidor Eric L Altschuler Sujata Ambardar Kathryn Anastos Ben Anderson Val Anderson Ushan Andrady Diana Antoniskis David Bangsberg Daniel Barbaro William Barrie J Bartczak Simon Barton Patricia Basden Nesli Basgoz Suzane Bazner Nicholaos C Bellos Anne M Benson Judith Berger Nicole F Bernard Annette M Bernard Christopher Birch Stanley J Bodner Robert K Bolan Emilie T Boudreaux Meg Bradley James F Braun Jon E Brndjar Stephen J Brown Katherine Brown Sheldon T Brown Jedidiah Burack Larry M Bush Virginia Cafaro Omobolaji Campbell John Campbell Robert H Carlson J Kevin Carmichael Kathleen K Casey Chris Cavacuiti Gregory Celestin Steven T Chambers Nancy Chez Lisa M Chirch Paul J Cimoch Daniel Cohen Lillian E Cohn Brian Conway David A Cooper Brian Cornelson David T Cox Michael V Cristofano George Cuchural Julie L Czartoski Joseph M Dahman Jennifer S Daly Benjamin T Davis Kristine Davis Sheila M Davod Edwin DeJesus Craig A Dietz Eleanor Dunham Michael E Dunn Todd B Ellerin Joseph J Eron John J W Fangman Claire E Farel Helen Ferlazzo Sarah Fidler Anita Fleenor-Ford Renee Frankel Kenneth A Freedberg Neel K French Jonathan D Fuchs Jon D Fuller Jonna Gaberman Joel E Gallant Rajesh T Gandhi Efrain Garcia Donald Garmon Joseph C Gathe Cyril R Gaultier Wondwoosen Gebre Frank D Gilman Ian Gilson Paul A Goepfert Michael S Gottlieb Claudia Goulston Richard K Groger T Douglas Gurley Stuart Haber Robin Hardwicke W David Hardy P Richard Harrigan Trevor N Hawkins Sonya Heath Frederick M Hecht W Keith Henry Melissa Hladek Robert P Hoffman James M Horton Ricky K Hsu Gregory D Huhn Peter Hunt Mark J Hupert Mark L Illeman Hans Jaeger Robert M Jellinger Mina John Jennifer A Johnson Kristin L Johnson Heather Johnson Kay Johnson Jennifer Joly Wilbert C Jordan Carol A Kauffman Homayoon Khanlou Robert K Killian Arthur Y Kim David D Kim Clifford A Kinder Jeffrey T Kirchner Laura Kogelman Erna Milunka Kojic P Todd Korthuis Wayne Kurisu Douglas S Kwon Melissa LaMar Harry Lampiris Massimiliano Lanzafame Michael M Lederman David M Lee Jean M L Lee Marah J Lee Edward T Y Lee Janice Lemoine Jay A Levy Josep M Llibre Michael A Liguori Susan J Little Anne Y Liu Alvaro J Lopez Mono R Loutfy Dawn Loy Debbie Y Mohammed Alan Man Michael K Mansour Vincent C Marconi Martin Markowitz Rui Marques Jeffrey N Martin Harold L Martin Kenneth Hugh Mayer M Juliana McElrath Theresa A McGhee Barbara H McGovern Katherine McGowan Dawn McIntyre Gavin X Mcleod Prema Menezes Greg Mesa Craig E Metroka Dirk Meyer-Olson Andy O Miller Kate Montgomery Karam C Mounzer Ellen H Nagami Iris Nagin Ronald G Nahass Margret O Nelson Craig Nielsen David L Norene David H O'Connor Bisola O Ojikutu Jason Okulicz Olakunle O Oladehin Edward C Oldfield Susan A Olender Mario Ostrowski William F Owen Eunice Pae Jeffrey Parsonnet Andrew M Pavlatos Aaron M Perlmutter Michael N Pierce Jonathan M Pincus Leandro Pisani Lawrence Jay Price Laurie Proia Richard C Prokesch Heather Calderon Pujet Moti Ramgopal Almas Rathod Michael Rausch J Ravishankar Frank S Rhame Constance Shamuyarira Richards Douglas D Richman Berta Rodes Milagros Rodriguez Richard C Rose Eric S Rosenberg Daniel Rosenthal Polly E Ross David S Rubin Elease Rumbaugh Luis Saenz Michelle R Salvaggio William C Sanchez Veeraf M Sanjana Steven Santiago Wolfgang Schmidt Hanneke Schuitemaker Philip M Sestak Peter Shalit William Shay Vivian N Shirvani Vanessa I Silebi James M Sizemore Paul R Skolnik Marcia Sokol-Anderson James M Sosman Paul Stabile Jack T Stapleton Sheree Starrett Francine Stein Hans-Jurgen Stellbrink F Lisa Sterman Valerie E Stone David R Stone Giuseppe Tambussi Randy A Taplitz Ellen M Tedaldi Amalio Telenti William Theisen Richard Torres Lorraine Tosiello Cecile Tremblay Marc A Tribble Phuong D Trinh Alice Tsao Peggy Ueda Anthony Vaccaro Emilia Valadas Thanes J Vanig Isabel Vecino Vilma M Vega Wenoah Veikley Barbara H Wade Charles Walworth Chingchai Wanidworanun Douglas J Ward Daniel A Warner Robert D Weber Duncan Webster Steve Weis David A Wheeler David J White Ed Wilkins Alan Winston Clifford G Wlodaver Angelique van't Wout David P Wright Otto O Yang David L Yurdin Brandon W Zabukovic Kimon C Zachary Beth Zeeman Meng Zhao

Science 2010 Dec 4;330(6010):1551-7. Epub 2010 Nov 4.

Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology (MIT) and Harvard, Boston, MA, USA.

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http://dx.doi.org/10.1126/science.1195271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235490PMC
December 2010

Correction for hidden confounders in the genetic analysis of gene expression.

Proc Natl Acad Sci U S A 2010 Sep 1;107(38):16465-70. Epub 2010 Sep 1.

Microsoft Research, 1100 Glendon Avenue, Suite PH1, Los Angeles, CA, USA.

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http://dx.doi.org/10.1073/pnas.1002425107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944732PMC
September 2010

Exploiting knowledge of immune selection in HIV-1 to detect HIV-specific CD8 T-cell responses.

Vaccine 2010 Aug 7;28(37):6052-7. Epub 2010 Jul 7.

Centre for Clinical Immunology and Biomedical Statistics, Institute of Immunology and Infectious Diseases, Murdoch University, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.vaccine.2010.06.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949439PMC
August 2010

Beyond atopy: multiple patterns of sensitization in relation to asthma in a birth cohort study.

Am J Respir Crit Care Med 2010 Jun 18;181(11):1200-6. Epub 2010 Feb 18.

The University of Manchester, Manchester Academic Health Science Centre, NIHR Translational Research Facility in Respiratory Medicine, University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom.

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http://dx.doi.org/10.1164/rccm.200907-1101OCDOI Listing
June 2010

Changes in impact of HLA class I allele expression on HIV-1 plasma virus loads at a population level over time.

Microbiol Immunol 2010 Apr;54(4):196-205

Division of Infectious Disease, Advanced Clinical Research Center, Department of Infectious Diseases and Applied Immunology, Research Hospital, and Department of Infectious Disease Control, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1111/j.1348-0421.2010.00206.xDOI Listing
April 2010

PhyloDet: a scalable visualization tool for mapping multiple traits to large evolutionary trees.

Bioinformatics 2009 Oct 24;25(19):2611-2. Epub 2009 Jul 24.

Microsoft Research, One Microsoft Way, Redmond, WA 98052, USA.

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http://dx.doi.org/10.1093/bioinformatics/btp454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752614PMC
October 2009

Shift-invariant adaptive double threading: learning MHC II-peptide binding.

J Comput Biol 2008 Sep;15(7):927-42

Bioinformatics Program, University of California, San Diego, La Jolla, California, USA.

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http://www.liebertpub.com/doi/10.1089/cmb.2007.0183
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http://dx.doi.org/10.1089/cmb.2007.0183DOI Listing
September 2008

Increased cytotoxic T-lymphocyte epitope variant cross-recognition and functional avidity are associated with hepatitis C virus clearance.

J Virol 2008 Mar 9;82(6):3147-53. Epub 2008 Jan 9.

Massachusetts General Hospital and Harvard Medical School, Partners AIDS Research Center, MGH East no. 5239, 149 13th St., Charlestown, MA 02143, USA.

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http://dx.doi.org/10.1128/JVI.02252-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258967PMC
March 2008

Efficient control of population structure in model organism association mapping.

Genetics 2008 Mar;178(3):1709-23

Department of Computer Science, University of California, Los Angeles, California 90095-1596, USA.

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http://dx.doi.org/10.1534/genetics.107.080101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278096PMC
March 2008

Statistical resolution of ambiguous HLA typing data.

PLoS Comput Biol 2008 Feb 29;4(2):e1000016. Epub 2008 Feb 29.

Microsoft Research, Redmond, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1000016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289775PMC
February 2008

Leveraging information across HLA alleles/supertypes improves epitope prediction.

J Comput Biol 2007 Jul-Aug;14(6):736-46

Microsoft Research, Redmond, WA 98052, USA.

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http://dx.doi.org/10.1089/cmb.2007.R013DOI Listing
September 2007