Publications by authors named "David H Rowitch"

100Publications

A classification of video-conferencing related illness: the zoomnotic diseases.

QJM 2020 Nov 27. Epub 2020 Nov 27.

Department of Obstetrics & Gynaecology, Cambridge University Clinical School, Cambridge, UK.

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http://dx.doi.org/10.1093/qjmed/hcaa316DOI Listing
November 2020

Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury.

Neuron 2020 Oct 13. Epub 2020 Oct 13.

Department of Pediatrics, UCSF, San Francisco, CA, USA; Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine, UCSF, San Francisco, CA, USA; New Born Brain Research Institute, UCSF, San Francisco, CA, USA; Department of Paediatrics and Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Hills Road, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2020.09.033DOI Listing
October 2020

Origins and Proliferative States of Human Oligodendrocyte Precursor Cells.

Cell 2020 Aug 16;182(3):594-608.e11. Epub 2020 Jul 16.

The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415734PMC
August 2020

Applying support-vector machine learning algorithms toward predicting host-guest interactions with cucurbit[7]uril.

Phys Chem Chem Phys 2020 Jul 26;22(26):14976-14982. Epub 2020 Jun 26.

Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.

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http://dx.doi.org/10.1039/c9cp05800aDOI Listing
July 2020

Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration.

Neuron 2020 03 7;105(5):855-866.e5. Epub 2020 Jan 7.

Department of Clinical Neurosciences and UK Dementia Research Institute at the University of Cambridge, Island Research Building, Cambridge Biomedical Campus, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054837PMC
March 2020

Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.

Cell Stem Cell 2019 Oct;25(4):531-541.e6

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.09.003DOI Listing
October 2019

Long-Term Safety, Immunologic Response, and Imaging Outcomes following Neural Stem Cell Transplantation for Pelizaeus-Merzbacher Disease.

Stem Cell Reports 2019 08 1;13(2):254-261. Epub 2019 Aug 1.

Department of Neurological Surgery, University of California San Francisco, 550 16(th) Street, 4(th) Floor, San Francisco, CA 94143-0137, USA; Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA; Department of Paediatrics, University of Cambridge, Cambridge CB2 1TN, UK.

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http://dx.doi.org/10.1016/j.stemcr.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700500PMC
August 2019

Single-cell genomics identifies cell type-specific molecular changes in autism.

Science 2019 05;364(6441):685-689

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/science.aav8130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678724PMC
May 2019

Ferret brain possesses young interneuron collections equivalent to human postnatal migratory streams.

J Comp Neurol 2019 12 15;527(17):2843-2859. Epub 2019 May 15.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cne.24711
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http://dx.doi.org/10.1002/cne.24711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773523PMC
December 2019

The neurointensive nursery: concept, development, and insights gained.

Curr Opin Pediatr 2019 04;31(2):202-209

Department Pediatrics, UCSF Benioff Children's Hospital.

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http://dx.doi.org/10.1097/MOP.0000000000000733DOI Listing
April 2019

New Recipes for Myelinating Oligodendrocytes.

Cell Stem Cell 2018 10;23(4):464-465

Departments of Pediatrics and Neurosurgery, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA 94143, USA; Department of Paediatrics, Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0QQ, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909183044
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http://dx.doi.org/10.1016/j.stem.2018.09.011DOI Listing
October 2018

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.

Cancer Cell 2018 05 19;33(5):874-889.e7. Epub 2018 Apr 19.

Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143, USA; Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine, University of California San Francisco, San Francisco, CA 94143, USA; Department of Neurological Surgery and Brain Tumor Research Center, University of California San Francisco, San Francisco, CA 94143, USA; Department of Pediatrics, University of Cambridge and Wellcome Trust-MRC Stem Cell Institute, Hills Road, Cambridge CB2 0AN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211172PMC
May 2018

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength.

Neuron 2018 04 5;98(2):306-319.e7. Epub 2018 Apr 5.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Departments of Pediatrics and Neurosurgery, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Paediatrics and Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB20QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919779PMC
April 2018

Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes.

Stem Cell Reports 2017 12 30;9(6):1745-1753. Epub 2017 Nov 30.

Department of Ophthalmology, University of California, San Francisco, CA 94143, USA; Department of Physiology, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.stemcr.2017.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785708PMC
December 2017

Origin and dynamics of oligodendrocytes in the developing brain: Implications for perinatal white matter injury.

Glia 2018 02 14;66(2):221-238. Epub 2017 Nov 14.

Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/glia.23256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765410PMC
February 2018

Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury.

Cerebellum 2018 Apr;17(2):213-227

Department of Pediatrics, Eli and Edythe Broad Institute for Stem Cell Research and Regenerative Medicine, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1007/s12311-017-0895-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849674PMC
April 2018

Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis.

Cereb Cortex 2018 11;28(11):3797-3815

Department of Psychiatry, Neuroscience Program and the Nina Ireland Laboratory of Developmental Neurobiology, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1093/cercor/bhx241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188538PMC
November 2018

Olig1 is required for noggin-induced neonatal myelin repair.

Ann Neurol 2017 Apr;81(4):560-571

Department of Pediatrics, Eli and Edythe Broad Center for Stem Cell Research and Regeneration Medicine, University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1002/ana.24907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401646PMC
April 2017

Functional diversity of astrocytes in neural circuit regulation.

Nat Rev Neurosci 2017 01 1;18(1):31-41. Epub 2016 Dec 1.

Department of Pediatrics, Neurological Surgery and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine, University of California San Francisco, San Francisco, California 94143, USA.

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http://www.nature.com/articles/nrn.2016.159
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http://dx.doi.org/10.1038/nrn.2016.159DOI Listing
January 2017

Concise Review: Stem Cell-Based Treatment of Pelizaeus-Merzbacher Disease.

Stem Cells 2017 02 23;35(2):311-315. Epub 2016 Nov 23.

Center for Basic and Translational Neuroscience, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/stem.2530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314962PMC
February 2017

Lineage-Restricted OLIG2-RTK Signaling Governs the Molecular Subtype of Glioma Stem-like Cells.

Cell Rep 2016 09;16(11):2838-2845

Division of Neurobiology, Barrow Brain Tumor Research Center, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.08.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024710PMC
September 2016

The Role of the Neurointensive Care Nursery for Neonatal Encephalopathy.

Clin Perinatol 2016 Sep;43(3):547-57

Department of Paediatrics, University of Cambridge, Cambridge, UK; Department of Pediatrics and Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.clp.2016.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988330PMC
September 2016

Identification of proliferative progenitors associated with prominent postnatal growth of the pons.

Nat Commun 2016 05 18;7:11628. Epub 2016 May 18.

Eli &Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California-San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/ncomms11628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873968PMC
May 2016

Astrocytes: The Final Frontier….

Neuron 2016 Jan;89(1):1-2

Departments of Pediatrics and Neurosurgery, University of California San Francisco, San Francisco, CA 94143, USA; Department of Paediatrics, University of Cambridge, Cambridge, CB2 0AH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2015.12.030DOI Listing
January 2016

Dysregulation of astrocyte extracellular signaling in Costello syndrome.

Sci Transl Med 2015 May;7(286):286ra66

Department of Ophthalmology, University of California, San Francisco, San Francisco, CA 94143, USA. Department of Physiology, University of California, San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa5645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474402PMC
May 2015

Astrocyte development and heterogeneity.

Cold Spring Harb Perspect Biol 2014 Nov 20;7(1):a020362. Epub 2014 Nov 20.

Department of Pediatrics and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine, University of California, San Francisco, San Francisco, California 94143 Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, California 94143.

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http://dx.doi.org/10.1101/cshperspect.a020362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292163PMC
November 2014

Postnatal growth of the human pons: a morphometric and immunohistochemical analysis.

J Comp Neurol 2015 Feb 2;523(3):449-62. Epub 2014 Dec 2.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California - San Francisco, San Francisco, CA, 94143; Department of Neurological Surgery, University of California - San Francisco, San Francisco, CA, 94143.

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http://dx.doi.org/10.1002/cne.23690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270924PMC
February 2015

Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis.

Cell 2014 Jul 10;158(2):383-396. Epub 2014 Jul 10.

Department of Pediatrics, Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA; Division of Neonatology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.04.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149873PMC
July 2014

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

Nature 2014 May 28;509(7499):189-94. Epub 2014 Apr 28.

1] Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California 94143, USA [2] Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California 94143, USA [3] Department of Pediatrics, University of California San Francisco, San Francisco, California 94143, USA [4] Department of Neurosurgery, University of California San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nature13161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057936PMC
May 2014

Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer.

Nat Neurosci 2014 Apr 9;17(4):506-12. Epub 2014 Mar 9.

1] Department of Pediatrics, University of California, San Francisco (UCSF), San Francisco, California, USA. [2] Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, UCSF, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nn.3676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975168PMC
April 2014

Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.

Neuron 2014 Feb;81(3):574-87

Department of Pediatrics, Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurosurgery, University of California, San Francisco, San Francisco, CA 94143, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2013.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979971PMC
February 2014

Evolving concepts of gliogenesis: a look way back and ahead to the next 25 years.

Neuron 2013 Oct;80(3):613-23

University of Massachusetts, and Howard Hughes Medical Institute, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2013.10.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221505PMC
October 2013

Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions.

Glia 2013 Sep 10;61(9):1518-32. Epub 2013 Jul 10.

Department of Pediatrics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1002/glia.22538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909648PMC
September 2013

Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2.

Nat Rev Neurosci 2012 Dec;13(12):819-31

Department of Neurobiology, Harvard Medical School, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/nrn3386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733228PMC
December 2012

STAT3-mediated astrogliosis protects myelin development in neonatal brain injury.

Ann Neurol 2012 Nov 31;72(5):750-65. Epub 2012 Aug 31.

Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/ana.23670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514566PMC
November 2012

Evidence that nuclear factor IA inhibits repair after white matter injury.

Ann Neurol 2012 Aug 17;72(2):224-33. Epub 2012 Jul 17.

Departments of Pediatrics and Neurosurgery, Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/ana.23590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3429638PMC
August 2012

Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord.

Development 2012 Jul 6;139(14):2477-87. Epub 2012 Jun 6.

Department of Pediatrics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research and Howard Hughes Medical Institute, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1242/dev.077214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3383225PMC
July 2012

Astrocytes and disease: a neurodevelopmental perspective.

Genes Dev 2012 May;26(9):891-907

Department of Pediatrics, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California at San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1101/gad.188326.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347787PMC
May 2012

Olig1 function is required for remyelination potential of transplanted neural progenitor cells in a model of viral-induced demyelination.

Exp Neurol 2012 May 17;235(1):380-7. Epub 2012 Mar 17.

Department of Molecular Biology and Biochemistry, University of California, Irvine 92697-3900, USA.

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http://dx.doi.org/10.1016/j.expneurol.2012.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350784PMC
May 2012

A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury.

Sci Transl Med 2011 Oct;3(105):105ra104

Division of Neonatology, Department of Pediatrics, University of California, San Francisco (UCSF), San Francisco, CA 94143, USA.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30027
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http://dx.doi.org/10.1126/scitranslmed.3002731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694585PMC
October 2011

Corridors of migrating neurons in the human brain and their decline during infancy.

Nature 2011 Sep 28;478(7369):382-6. Epub 2011 Sep 28.

Eli and Edythe Broad Institute of Regeneration Medicine and Stem Cell Research, Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California 94143, USA.

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http://www.nature.com/articles/nature10487
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http://dx.doi.org/10.1038/nature10487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197903PMC
September 2011

Myelin regeneration in multiple sclerosis: targeting endogenous stem cells.

Neurotherapeutics 2011 Oct;8(4):650-8

MRC Cambridge Centre for Stem Cell Biology and Regenerative Medicine, and Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, United Kingdom.

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http://dx.doi.org/10.1007/s13311-011-0065-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250284PMC
October 2011

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination.

Nat Neurosci 2011 Jun 26;14(8):1009-16. Epub 2011 Jun 26.

Department of Pediatrics and Neurosurgery, Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nn.2855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145042PMC
June 2011

Myelin regeneration: a recapitulation of development?

Annu Rev Neurosci 2011 ;34:21-43

Departments of Pediatrics and Neurosurgery, Eli and Edyth Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, University of California, San Francisco, California 94143, USA.

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http://www.annualreviews.org/doi/10.1146/annurev-neuro-06101
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http://dx.doi.org/10.1146/annurev-neuro-061010-113629DOI Listing
October 2011

Myelin restoration: progress and prospects for human cell replacement therapies.

Arch Immunol Ther Exp (Warsz) 2011 Jun 2;59(3):179-93. Epub 2011 Apr 2.

Department of Pediatrics, UCSF, 513 Parnassus Avenue, San Francisco, CA 94143-0525, USA.

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http://dx.doi.org/10.1007/s00005-011-0120-7DOI Listing
June 2011

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma.

Proc Natl Acad Sci U S A 2011 Mar 1;108(11):4453-8. Epub 2011 Mar 1.

Department of Neurology, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.1101657108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060250PMC
March 2011

Developmental genetics of vertebrate glial-cell specification.

Nature 2010 Nov;468(7321):214-22

Howard Hughes Medical Institute, University of California, San Francisco, USA.

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http://search.proquest.com/openview/5974787dd7e2357687e42768
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http://dx.doi.org/10.1038/nature09611DOI Listing
November 2010

NIH consensus development conference: Inhaled nitric oxide therapy for premature infants.

NIH Consens State Sci Statements 2010 Oct;27(5):1-34

Department of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, and St. Louis Children’s Hospital, St. Louis, Missouri, USA.

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October 2010

Towards improved animal models of neonatal white matter injury associated with cerebral palsy.

Dis Model Mech 2010 Nov-Dec;3(11-12):678-88

Department of Pediatrics, Eli and Edythe Broad Institute for Stem Cell Research and Regeneration Medicine, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1242/dmm.002915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965396PMC
February 2011

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination.

Ann Neurol 2010 Nov;68(5):703-16

Department of Pediatrics, University of California at San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1002/ana.22090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966537PMC
November 2010

Cerebellar abnormalities following hypoxia alone compared to hypoxic-ischemic forebrain injury in the developing rat brain.

Neurobiol Dis 2011 Jan 16;41(1):138-46. Epub 2010 Sep 16.

Department of Neurology and Pediatrics, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910430PMC
January 2011

Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma.

Cancer Res 2010 Jul 8;70(13):5220-5. Epub 2010 Jun 8.

Department of Pediatrics and Neurosurgery, Howard Hughes Medical Institute and Institute for Regeneration Medicine, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896447PMC
July 2010

Overcoming remyelination failure in multiple sclerosis and other myelin disorders.

Exp Neurol 2010 Sep 4;225(1):18-23. Epub 2010 Jan 4.

Department of Pediatrics, Eli and Edyth Broad Institute for Stem Cell Research and Regeneration Medicine and Howard Hughes Medical Institute, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1016/j.expneurol.2009.12.020DOI Listing
September 2010

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

Proc Natl Acad Sci U S A 2009 Nov 23;106(45):19162-7. Epub 2009 Oct 23.

Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.0902834106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776461PMC
November 2009

A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.

J Neurosci 2009 Sep;29(36):11399-408

Department of Cancer Biology, Dana-Farber Cancer Institute, and Departments of Neurobiology and Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.0160-09.2
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http://dx.doi.org/10.1523/JNEUROSCI.0160-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775518PMC
September 2009

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade.

Proc Natl Acad Sci U S A 2009 Aug 5;106(33):14132-7. Epub 2009 Aug 5.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.0907134106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721821PMC
August 2009

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.

Genes Dev 2009 Jul 10;23(13):1571-85. Epub 2009 Jun 10.

Institute for Regeneration Medicine, Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1101/gad.1806309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704469PMC
July 2009

Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism.

J Clin Invest 2009 Feb 26;119(2):267-77. Epub 2009 Jan 26.

Department of Pediatrics, Howard Hughes Medical Institute and Institute for Regeneration Medicine, UCSF, San Francisco, California, USA.

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http://dx.doi.org/10.1172/JCI36376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631296PMC
February 2009