David Goltzman

David Goltzman

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David Goltzman

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The Aging Skeleton.

Authors:
David Goltzman

Adv Exp Med Biol 2019 ;1164:153-160

Department of Medicine, McGill University and McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/978-3-030-22254-3_12DOI Listing
October 2019

DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide.

Int J Biol Sci 2018 5;14(5):508-517. Epub 2018 Apr 5.

State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.7150/ijbs.23318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968843PMC
July 2019

Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification.

JCI Insight 2019 Jul 11;4(13). Epub 2019 Jul 11.

Department of Medicine, McGill University and McGill University Health Centre, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1172/jci.insight.126467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629247PMC
July 2019

1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling.

Aging Cell 2019 Jun 24;18(3):e12951. Epub 2019 Mar 24.

State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1111/acel.12951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516172PMC
June 2019

Nonparathyroid Hypercalcemia.

Authors:
David Goltzman

Front Horm Res 2019 19;51:77-90. Epub 2018 Nov 19.

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http://dx.doi.org/10.1159/000491040DOI Listing
April 2019

The Radiology of Osteoporotic Vertebral Fractures Revisited.

J Bone Miner Res 2019 Mar 27;34(3):409-418. Epub 2019 Feb 27.

Department of Radiology and Nuclear Medicine, University Medical Center Rotterdam, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/jbmr.3669DOI Listing
March 2019

Physiology of the Calcium-Parathyroid Hormone-Vitamin D Axis.

Front Horm Res 2018 29;50:1-13. Epub 2018 Mar 29.

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http://dx.doi.org/10.1159/000486060DOI Listing
January 2019

Evolution of Our Understanding of the Hyperparathyroid Syndromes: A Historical Perspective.

J Bone Miner Res 2019 Jan 10;34(1):22-37. Epub 2018 Dec 10.

Calcium Research Laboratory, Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Canada.

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http://dx.doi.org/10.1002/jbmr.3650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396287PMC
January 2019

Physiology of Parathyroid Hormone.

Authors:
David Goltzman

Endocrinol Metab Clin North Am 2018 12 11;47(4):743-758. Epub 2018 Oct 11.

Department of Medicine and Research Institute of the McGill University Health Centre, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada; Departments of Medicine and of Physiology, McGill University, 845 Sherbrooke St West, Montreal, Quebec H3A 0B9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ecl.2018.07.003DOI Listing
December 2018

Identification of an Epigenetic Signature of Osteoporosis in Blood DNA of Postmenopausal Women.

J Bone Miner Res 2018 11 20;33(11):1980-1989. Epub 2018 Jul 20.

Department of Medicine, McGill University Health Center, Montreal, QC, Canada.

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http://doi.wiley.com/10.1002/jbmr.3527
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http://dx.doi.org/10.1002/jbmr.3527DOI Listing
November 2018

1,25-dihydroxyvitamin D deficiency accelerates alveolar bone loss independent of aging and extracellular calcium and phosphorus.

J Periodontol 2018 08;89(8):983-994

State Key Laboratory of Reproductive Medicine, Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, PR China.

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http://doi.wiley.com/10.1002/JPER.17-0542
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http://dx.doi.org/10.1002/JPER.17-0542DOI Listing
August 2018

Osteoporotic Vertebral Fracture Prevalence Varies Widely: Reply Letter to the Editor.

J Bone Miner Res 2018 08 16;33(8):1547. Epub 2018 Jul 16.

Department of Radiology, University of British Columbia, Vancouver, Canada, for The CaMos Research Group.

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http://dx.doi.org/10.1002/jbmr.3540DOI Listing
August 2018

1,25-Dihydroxy vitamin D prevents tumorigenesis by inhibiting oxidative stress and inducing tumor cellular senescence in mice.

Int J Cancer 2018 07 1;143(2):368-382. Epub 2018 Mar 1.

State Key Laboratory of Reproductive Medicine, Department of Anatomy, Histology and Embryology, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/ijc.31317DOI Listing
July 2018

FAM210A is a novel determinant of bone and muscle structure and strength.

Proc Natl Acad Sci U S A 2018 04 4;115(16):E3759-E3768. Epub 2018 Apr 4.

Calcium Research Laboratory, Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, QC, Canada H4A 3J1;

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http://dx.doi.org/10.1073/pnas.1719089115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910842PMC
April 2018

Tumor-associated macrophages induce the expression of FOXQ1 to promote epithelial-mesenchymal transition and metastasis in gastric cancer cells.

Oncol Rep 2017 Oct 3;38(4):2003-2010. Epub 2017 Aug 3.

Departments of Medicine and Physiology, McGill University, Montreal, Quebec H3A 1A1, Canada.

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http://dx.doi.org/10.3892/or.2017.5877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652949PMC
October 2017

Effects of the Administration of 25(OH) Vitamin D3 in an Experimental Model of Chronic Kidney Disease in Animals Null for 1-Alpha-Hydroxylase.

PLoS One 2017 20;12(1):e0170654. Epub 2017 Jan 20.

Vascular and Renal Translational Research Group, REDinREN del ISCIII, IRBLleida, University Hospital Arnau de Vilanova, Lleida, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170654PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249163PMC
August 2017

A 51-item calcium-focused food frequency questionnaire is a reliable tool to assess dietary calcium intake in postmenopausal women.

Nutr Res 2017 Jul 18;43:33-42. Epub 2017 May 18.

Division of General Internal Medicine, Research Institute of McGill University Health Centre, Montreal, Québec, Canada H3G 1A4; Department of Medicine, McGill University, Montreal, Québec, Canada H3G 1Y6. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02715317173015
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http://dx.doi.org/10.1016/j.nutres.2017.05.006DOI Listing
July 2017

Trabecular Bone Score and Incident Fragility Fracture Risk in Adults with Reduced Kidney Function.

Clin J Am Soc Nephrol 2016 11 24;11(11):2032-2040. Epub 2016 Oct 24.

Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.

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http://dx.doi.org/10.2215/CJN.00720116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108183PMC
November 2016

Vascular Calcification Induced by Chronic Kidney Disease Is Mediated by an Increase of 1α-Hydroxylase Expression in Vascular Smooth Muscle Cells.

J Bone Miner Res 2016 10 4;31(10):1865-1876. Epub 2016 May 4.

Nephrology Research Department, REDinREN del ISCIII, IRBLleida, University Hospital Arnau de Vilanova, Lleida, Spain.

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http://dx.doi.org/10.1002/jbmr.2852DOI Listing
October 2016

Transplantation of bone marrow-derived mesenchymal stem cells rescues partially rachitic phenotypes induced by 1,25-Dihydroxyvitamin D deficiency in mice.

Am J Transl Res 2016 15;8(10):4382-4393. Epub 2016 Oct 15.

The State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University Nanjing, Jiangsu, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095331PMC
October 2016

Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease.

Circ Cardiovasc Genet 2016 Aug 14;9(4):349-56. Epub 2016 Jul 14.

From the Department of Epidemiology, Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada (D.M., L.E.M., S.R., J.B.R.); Departments of Medicine (D.G., J.B.R.) and Human Genetics (J.B.R.), McGill University, Montreal, Quebec, Canada; and Department of Twin Research and Genetic Epidemiology, King's College London, United Kingdom (J.B.R.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001396DOI Listing
August 2016

Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment.

Sci Rep 2016 07 4;6:29171. Epub 2016 Jul 4.

The State Key Laboratory of Reproductive Medicine, the Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1038/srep29171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931581PMC
July 2016

PTHrP Nuclear Localization and Carboxyl Terminus Sequences Modulate Dental and Mandibular Development in Part via the Action of p27.

Endocrinology 2016 Apr 9;157(4):1372-84. Epub 2016 Feb 9.

State Key Laboratory of Reproductive Medicine (W.S., J.W., L.H., H.L., R.W., D.M.), The Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Nanjing 210029, Jiangsu, People's Republic of China; and Lady Davis Institute for Medical Research (A.K.), Jewish General Hospital, and Calcium Research Laboratory (D.G.), McGill University Health Centre and Department of Medicine, McGill University, Montréal, Québec, Canada H3A 1A1.

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http://dx.doi.org/10.1210/en.2015-1555DOI Listing
April 2016

Androgens Attenuate Vitamin D Production Induced by UVB Irradiation of the Skin of Male Mice by an Enzymatic Mechanism.

J Invest Dermatol 2015 Dec 27;135(12):3125-3132. Epub 2015 Jul 27.

Department of Medicine, Calcium Research Laboratory and the Centre for Translational Biology, McGill University Health Centre Montreal, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.297DOI Listing
December 2015

The p27 Pathway Modulates the Regulation of Skeletal Growth and Osteoblastic Bone Formation by Parathyroid Hormone-Related Peptide.

J Bone Miner Res 2015 Nov 30;30(11):1969-79. Epub 2015 Jun 30.

State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Nanjing, People's Republic of China.

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http://dx.doi.org/10.1002/jbmr.2544DOI Listing
November 2015

Deficiency of the parathyroid hormone-related peptide nuclear localization and carboxyl terminal sequences leads to premature skin ageing partially mediated by the upregulation of p27.

Exp Dermatol 2015 Nov 15;24(11):847-52. Epub 2015 Sep 15.

Department of Anatomy, Histology and Embryology, State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.1111/exd.12789DOI Listing
November 2015

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.

Authors:
Hou-Feng Zheng Vincenzo Forgetta Yi-Hsiang Hsu Karol Estrada Alberto Rosello-Diez Paul J Leo Chitra L Dahia Kyung Hyun Park-Min Jonathan H Tobias Charles Kooperberg Aaron Kleinman Unnur Styrkarsdottir Ching-Ti Liu Charlotta Uggla Daniel S Evans Carrie M Nielson Klaudia Walter Ulrika Pettersson-Kymmer Shane McCarthy Joel Eriksson Tony Kwan Mila Jhamai Katerina Trajanoska Yasin Memari Josine Min Jie Huang Petr Danecek Beth Wilmot Rui Li Wen-Chi Chou Lauren E Mokry Alireza Moayyeri Melina Claussnitzer Chia-Ho Cheng Warren Cheung Carolina Medina-Gómez Bing Ge Shu-Huang Chen Kwangbom Choi Ling Oei James Fraser Robert Kraaij Matthew A Hibbs Celia L Gregson Denis Paquette Albert Hofman Carl Wibom Gregory J Tranah Mhairi Marshall Brooke B Gardiner Katie Cremin Paul Auer Li Hsu Sue Ring Joyce Y Tung Gudmar Thorleifsson Anke W Enneman Natasja M van Schoor Lisette C P G M de Groot Nathalie van der Velde Beatrice Melin John P Kemp Claus Christiansen Adrian Sayers Yanhua Zhou Sophie Calderari Jeroen van Rooij Chris Carlson Ulrike Peters Soizik Berlivet Josée Dostie Andre G Uitterlinden Stephen R Williams Charles Farber Daniel Grinberg Andrea Z LaCroix Jeff Haessler Daniel I Chasman Franco Giulianini Lynda M Rose Paul M Ridker John A Eisman Tuan V Nguyen Jacqueline R Center Xavier Nogues Natalia Garcia-Giralt Lenore L Launer Vilmunder Gudnason Dan Mellström Liesbeth Vandenput Najaf Amin Cornelia M van Duijn Magnus K Karlsson Östen Ljunggren Olle Svensson Göran Hallmans François Rousseau Sylvie Giroux Johanne Bussière Pascal P Arp Fjorda Koromani Richard L Prince Joshua R Lewis Bente L Langdahl A Pernille Hermann Jens-Erik B Jensen Stephen Kaptoge Kay-Tee Khaw Jonathan Reeve Melissa M Formosa Angela Xuereb-Anastasi Kristina Åkesson Fiona E McGuigan Gaurav Garg Jose M Olmos Maria T Zarrabeitia Jose A Riancho Stuart H Ralston Nerea Alonso Xi Jiang David Goltzman Tomi Pastinen Elin Grundberg Dominique Gauguier Eric S Orwoll David Karasik George Davey-Smith Albert V Smith Kristin Siggeirsdottir Tamara B Harris M Carola Zillikens Joyce B J van Meurs Unnur Thorsteinsdottir Matthew T Maurano Nicholas J Timpson Nicole Soranzo Richard Durbin Scott G Wilson Evangelia E Ntzani Matthew A Brown Kari Stefansson David A Hinds Tim Spector L Adrienne Cupples Claes Ohlsson Celia M T Greenwood Rebecca D Jackson David W Rowe Cynthia A Loomis David M Evans Cheryl L Ackert-Bicknell Alexandra L Joyner Emma L Duncan Douglas P Kiel Fernando Rivadeneira J Brent Richards

Nature 2015 Oct 14;526(7571):112-7. Epub 2015 Sep 14.

Departments of Medicine, Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal H3A 1A2, Canada.

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http://dx.doi.org/10.1038/nature14878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755714PMC
October 2015

Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis.

Endocrinology 2015 Aug 8;156(8):2774-80. Epub 2015 Jun 8.

Endocrine Unit (T.H., T.K., S.N., H.M.K.), Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts; Sir Mortimer B. Davis Jewish General Hospital (A.C.K.), McGill University, Montreal, Québec, Canada H3T 1E2; and Royal Victoria Hospital of the McGill University Health Centre (D.G.), Montreal, Québec, Canada H3A 1A1.

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http://dx.doi.org/10.1210/en.2014-1835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511135PMC
August 2015

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study.

PLoS Med 2015 Aug 25;12(8):e1001866. Epub 2015 Aug 25.

Centre for Clinical Epidemiology, Department of Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada; Department of Medicine, McGill University, Montreal, Quebec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada; Department of Human Genetics, McGill University, Montreal, Quebec, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549308PMC
August 2015

Teriparatide and bone turnover and formation in a hemodialysis patient with low-turnover bone disease: a case report.

Am J Kidney Dis 2015 Jun 2;65(6):933-6. Epub 2015 Apr 2.

Division of Endocrinology and Metabolism, University of Toronto and Women's College Research Institute, Toronto, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02726386150049
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http://dx.doi.org/10.1053/j.ajkd.2015.01.025DOI Listing
June 2015

The calcium-sensing receptor in bone--mechanistic and therapeutic insights.

Nat Rev Endocrinol 2015 May 10;11(5):298-307. Epub 2015 Mar 10.

Department of Medicine, McGill University, 687 Pine Avenue West, Montreal, QC H3A 1A1, Canada.

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http://dx.doi.org/10.1038/nrendo.2015.30DOI Listing
May 2015

Comparison of fracture risk prediction among individuals with reduced and normal kidney function.

Clin J Am Soc Nephrol 2015 Apr 5;10(4):646-53. Epub 2015 Feb 5.

Department of Medicine, University of Toronto, Toronto, Ontario, Canada; and Women's College Hospital and Women's College Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2215/CJN.06040614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386249PMC
April 2015

Administration of exogenous 1,25(OH)2D3 normalizes overactivation of the central renin-angiotensin system in 1α(OH)ase knockout mice.

Neurosci Lett 2015 Feb 7;588:184-9. Epub 2015 Jan 7.

Department of Human Anatomy, Nanjing Medical University, Nanjing, Jiangsu 210029, PR China.

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http://dx.doi.org/10.1016/j.neulet.2015.01.013DOI Listing
February 2015

Active vitamin D deficiency mediated by extracellular calcium and phosphorus results in male infertility in young mice.

Am J Physiol Endocrinol Metab 2015 Jan 4;308(1):E51-62. Epub 2014 Nov 4.

State Key Laboratory of Reproductive Medicine, Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Jiangsu, China; and

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http://dx.doi.org/10.1152/ajpendo.00076.2014DOI Listing
January 2015

The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study.

PLoS Med 2014 Oct 28;11(10):e1001751. Epub 2014 Oct 28.

Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada; Department of Medicine, McGill University, Montreal, Quebec, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211663PMC
October 2014

A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism.

J Cell Mol Med 2014 Aug 20;18(8):1588-98. Epub 2014 Jun 20.

Department of Biochemistry, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1111/jcmm.12327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152406PMC
August 2014

Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation.

J Allergy Clin Immunol 2014 May 22;133(5):1356-64, 1364.e1-14. Epub 2014 Jan 22.

Division of Human Immunology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia; University of Adelaide, Adelaide, Australia; University of South Australia, Adelaide, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154631PMC
May 2014

1, 25(OH)₂D₃ inhibits hepatocellular carcinoma development through reducing secretion of inflammatory cytokines from immunocytes.

Curr Med Chem 2013 ;20(33):4131-41

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an 710061, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112515PMC
http://dx.doi.org/10.2174/09298673113209990248DOI Listing
April 2014

In healthy adults, biological activity of vitamin D, as assessed by serum PTH, is largely independent of DBP concentrations.

J Bone Miner Res 2014 Feb;29(2):494-9

Department of Human Genetics and Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada.

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http://doi.wiley.com/10.1002/jbmr.2042
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http://dx.doi.org/10.1002/jbmr.2042DOI Listing
February 2014

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

J Med Genet 2014 Feb 16;51(2):122-31. Epub 2013 Dec 16.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://www.molepi.nl/uploads/publicaties/2014/2014_oei_jmedg
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http://jmg.bmj.com/cgi/doi/10.1136/jmedgenet-2013-102064
Publisher Site
http://dx.doi.org/10.1136/jmedgenet-2013-102064DOI Listing
February 2014

Calcium sensing receptor absence delays postnatal brain development via direct and indirect mechanisms.

Mol Neurobiol 2013 Dec 7;48(3):590-600. Epub 2013 Apr 7.

Department of Anatomy, Nanjing Medical University, Nanjing, Jiangsu, 210029, People's Republic of China.

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http://dx.doi.org/10.1007/s12035-013-8448-0DOI Listing
December 2013

Plasma FGF23 levels increase rapidly after acute kidney injury.

Kidney Int 2013 Oct 8;84(4):776-85. Epub 2013 May 8.

1] Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA [2] Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ki.2013.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766419PMC
October 2013

Endogenous parathyroid hormone-related protein compensates for the absence of parathyroid hormone in promoting bone accrual in vivo in a model of bone marrow ablation.

J Bone Miner Res 2013 Sep;28(9):1898-911

The State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/jbmr.2000DOI Listing
September 2013

1,25(OH)2D deficiency induces temporomandibular joint osteoarthritis via secretion of senescence-associated inflammatory cytokines.

Bone 2013 Aug 25;55(2):400-9. Epub 2013 Apr 25.

Institute of Stomatology, Nanjing Medical University, No. 140, Han Zhong Road, Nanjing 210029, Jiangsu, People's Republic of China.

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http://dx.doi.org/10.1016/j.bone.2013.04.015DOI Listing
August 2013

Parathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium-sensing receptor gene deletion.

Eur J Haematol 2013 Jul 27;91(1):37-45. Epub 2013 Apr 27.

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/ejh.12110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689863PMC
July 2013

CaSR-mediated interactions between calcium and magnesium homeostasis in mice.

Am J Physiol Endocrinol Metab 2013 Apr 29;304(7):E724-33. Epub 2013 Jan 29.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpendo.00557.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625753PMC
April 2013

Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo.

Am J Physiol Endocrinol Metab 2013 Feb 11;304(3):E310-20. Epub 2012 Dec 11.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpendo.00460.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566433PMC
February 2013

Defective postnatal endochondral bone development by chondrocyte-specific targeted expression of parathyroid hormone type 2 receptor.

Am J Physiol Endocrinol Metab 2012 Dec 23;303(12):E1489-501. Epub 2012 Oct 23.

Division of Endocrinology, Department of Medicine and Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1152/ajpendo.00254.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532463PMC
December 2012

Absence of PTHrP nuclear localization and carboxyl terminus sequences leads to abnormal brain development and function.

PLoS One 2012 23;7(7):e41542. Epub 2012 Jul 23.

State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402381PMC
November 2012

Vitamin D receptor as a master regulator of the c-MYC/MXD1 network.

Proc Natl Acad Sci U S A 2012 Nov 29;109(46):18827-32. Epub 2012 Oct 29.

Department of Medicine, McGill University, Montreal, QC, Canada H3G 1Y6.

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http://dx.doi.org/10.1073/pnas.1210037109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503153PMC
November 2012

Assessment of gene-by-sex interaction effect on bone mineral density.

J Bone Miner Res 2012 Oct;27(10):2051-64

Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue CT3, Boston,MA 02118, USA.

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http://dx.doi.org/10.1002/jbmr.1679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447125PMC
October 2012

Bone marrow ablation demonstrates that excess endogenous parathyroid hormone plays distinct roles in trabecular and cortical bone.

Am J Pathol 2012 Jul 26;181(1):234-44. Epub 2012 May 26.

Department of Orthopedics, Second Affiliated Hospital of Soochow University, Suzhou, China.

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http://dx.doi.org/10.1016/j.ajpath.2012.03.038DOI Listing
July 2012

The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice.

Am J Physiol Endocrinol Metab 2012 Apr 24;302(7):E841-51. Epub 2012 Jan 24.

Calcium Research Laboratory, McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.1152/ajpendo.00599.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330707PMC
April 2012

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

Authors:
Karol Estrada Unnur Styrkarsdottir Evangelos Evangelou Yi-Hsiang Hsu Emma L Duncan Evangelia E Ntzani Ling Oei Omar M E Albagha Najaf Amin John P Kemp Daniel L Koller Guo Li Ching-Ti Liu Ryan L Minster Alireza Moayyeri Liesbeth Vandenput Dana Willner Su-Mei Xiao Laura M Yerges-Armstrong Hou-Feng Zheng Nerea Alonso Joel Eriksson Candace M Kammerer Stephen K Kaptoge Paul J Leo Gudmar Thorleifsson Scott G Wilson James F Wilson Ville Aalto Markku Alen Aaron K Aragaki Thor Aspelund Jacqueline R Center Zoe Dailiana David J Duggan Melissa Garcia Natàlia Garcia-Giralt Sylvie Giroux Göran Hallmans Lynne J Hocking Lise Bjerre Husted Karen A Jameson Rita Khusainova Ghi Su Kim Charles Kooperberg Theodora Koromila Marcin Kruk Marika Laaksonen Andrea Z Lacroix Seung Hun Lee Ping C Leung Joshua R Lewis Laura Masi Simona Mencej-Bedrac Tuan V Nguyen Xavier Nogues Millan S Patel Janez Prezelj Lynda M Rose Serena Scollen Kristin Siggeirsdottir Albert V Smith Olle Svensson Stella Trompet Olivia Trummer Natasja M van Schoor Jean Woo Kun Zhu Susana Balcells Maria Luisa Brandi Brendan M Buckley Sulin Cheng Claus Christiansen Cyrus Cooper George Dedoussis Ian Ford Morten Frost David Goltzman Jesús González-Macías Mika Kähönen Magnus Karlsson Elza Khusnutdinova Jung-Min Koh Panagoula Kollia Bente Lomholt Langdahl William D Leslie Paul Lips Östen Ljunggren Roman S Lorenc Janja Marc Dan Mellström Barbara Obermayer-Pietsch José M Olmos Ulrika Pettersson-Kymmer David M Reid José A Riancho Paul M Ridker François Rousseau P Eline Slagboom Nelson L S Tang Roser Urreizti Wim Van Hul Jorma Viikari María T Zarrabeitia Yurii S Aulchenko Martha Castano-Betancourt Elin Grundberg Lizbeth Herrera Thorvaldur Ingvarsson Hrefna Johannsdottir Tony Kwan Rui Li Robert Luben Carolina Medina-Gómez Stefan Th Palsson Sjur Reppe Jerome I Rotter Gunnar Sigurdsson Joyce B J van Meurs Dominique Verlaan Frances M K Williams Andrew R Wood Yanhua Zhou Kaare M Gautvik Tomi Pastinen Soumya Raychaudhuri Jane A Cauley Daniel I Chasman Graeme R Clark Steven R Cummings Patrick Danoy Elaine M Dennison Richard Eastell John A Eisman Vilmundur Gudnason Albert Hofman Rebecca D Jackson Graeme Jones J Wouter Jukema Kay-Tee Khaw Terho Lehtimäki Yongmei Liu Mattias Lorentzon Eugene McCloskey Braxton D Mitchell Kannabiran Nandakumar Geoffrey C Nicholson Ben A Oostra Munro Peacock Huibert A P Pols Richard L Prince Olli Raitakari Ian R Reid John Robbins Philip N Sambrook Pak Chung Sham Alan R Shuldiner Frances A Tylavsky Cornelia M van Duijn Nick J Wareham L Adrienne Cupples Michael J Econs David M Evans Tamara B Harris Annie Wai Chee Kung Bruce M Psaty Jonathan Reeve Timothy D Spector Elizabeth A Streeten M Carola Zillikens Unnur Thorsteinsdottir Claes Ohlsson David Karasik J Brent Richards Matthew A Brown Kari Stefansson André G Uitterlinden Stuart H Ralston John P A Ioannidis Douglas P Kiel Fernando Rivadeneira

Nat Genet 2012 Apr 15;44(5):491-501. Epub 2012 Apr 15.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://kooperberg.fhcrc.org/papers/2012estrada.pdf
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http://dx.doi.org/10.1038/ng.2249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338864PMC
April 2012

The LDLR deficient mouse as a model for aortic calcification and quantification by micro-computed tomography.

Atherosclerosis 2011 Dec 26;219(2):455-62. Epub 2011 Aug 26.

Institut de Recherches Cliniques, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.08.035DOI Listing
December 2011

The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus, and PTH.

PLoS Genet 2011 Sep 22;7(9):e1002294. Epub 2011 Sep 22.

State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology, and Embryology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1371/journal.pgen.1002294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178615PMC
September 2011