David Goldman

David Goldman

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David Goldman

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Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis.

JAMA Netw Open 2019 Nov 1;2(11):e1914940. Epub 2019 Nov 1.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.14940DOI Listing
November 2019

Commentary on: "Combination immunotherapy with passive antibody and sulfasalazine accelerates fungal clearance and promotes the resolution of Pneumocystis associated immunopathogenesis".

Authors:
David L Goldman

Infect Immun 2019 Nov 11. Epub 2019 Nov 11.

Departments of Pediatrics and Microbiology & Immunology. The Children's Hospital at Montefiore and the Albert Einstein College of Medicine

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http://dx.doi.org/10.1128/IAI.00844-19DOI Listing
November 2019

TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity.

Addict Biol 2019 Nov 12:e12838. Epub 2019 Nov 12.

National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1111/adb.12838DOI Listing
November 2019

Bronchoscopy in severe childhood asthma: Irresponsible or irreplaceable?

Pediatr Pulmonol 2019 Nov 15. Epub 2019 Nov 15.

Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1002/ppul.24569DOI Listing
November 2019

Neurofunctional Domains Derived From Deep Behavioral Phenotyping in Alcohol Use Disorder.

Am J Psychiatry 2019 Sep 4;176(9):744-753. Epub 2019 Jan 4.

Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism (NIAAA), Bethesda (Kwako, Schwandt, Diazgranados, Goldman); Section on Human Psychopharmacology, NIAAA, Bethesda (Ramchandani); Office of the Director, NIAAA, Bethesda (Koob); Office of the Director, NIDA, Bethesda (Volkow); Division of Epidemiology, Services, and Prevention, NIDA, Bethesda (Blanco); and Laboratory of Neurogenetics, NIAAA, Bethesda (Goldman).

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http://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2018.18
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http://dx.doi.org/10.1176/appi.ajp.2018.18030357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609498PMC
September 2019

OPRM1 rs1799971, COMT rs4680, and FAAH rs324420 genes interact with placebo procedures to induce hypoalgesia.

Pain 2019 Aug;160(8):1824-1834

Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, Baltimore, MD, United States.

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http://dx.doi.org/10.1097/j.pain.0000000000001578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668362PMC
August 2019

Predicting Depression.

Authors:
David Goldman

Am J Psychiatry 2019 Aug;176(8):598-599

Office of the Clinical Director, and Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, Rockville, Md.

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http://dx.doi.org/10.1176/appi.ajp.2019.19060590DOI Listing
August 2019

Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha.

Proc Natl Acad Sci U S A 2019 Aug 12;116(35):17531-17540. Epub 2019 Aug 12.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada;

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http://dx.doi.org/10.1073/pnas.1907077116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717308PMC
August 2019

Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer.

PLoS Comput Biol 2019 Aug 26;15(8):e1007278. Epub 2019 Aug 26.

Division of Engineering in Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1007278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709889PMC
August 2019

Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2.

Neuropsychopharmacology 2019 Aug 29. Epub 2019 Aug 29.

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41386-019-0500-yDOI Listing
August 2019

Early-Life Adversity and Blunted Stress Reactivity as Predictors of Alcohol and Drug use in Persons With COMT (rs4680) Val158Met Genotypes.

Alcohol Clin Exp Res 2019 Jul 31;43(7):1519-1527. Epub 2019 May 31.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1111/acer.14079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602827PMC
July 2019

Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype.

Proc Natl Acad Sci U S A 2019 Jun 10;116(26):13107-13115. Epub 2019 Jun 10.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20852;

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http://dx.doi.org/10.1073/pnas.1820410116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600920PMC
June 2019

Ting-Kai Li, M.D.

Authors:
David Goldman

Neuropsychopharmacology 2019 05 11;44(6):1176. Epub 2019 Mar 11.

Laboratory of Neurogenetics, Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.

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http://www.nature.com/articles/s41386-019-0358-z
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http://dx.doi.org/10.1038/s41386-019-0358-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461965PMC
May 2019

Nontuberculous Mycobacterial Infections in Children.

Pediatr Rev 2019 Apr;40(4):179-190

Department of Pediatrics and Microbiology and Immunology, Children's Hospital at Montefiore/Albert Einstein College of Medicine, Bronx, NY.

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http://dx.doi.org/10.1542/pir.2018-0131DOI Listing
April 2019

Ventral midbrain astrocytes display unique physiological features and sensitivity to dopamine D2 receptor signaling.

Neuropsychopharmacology 2019 01 13;44(2):344-355. Epub 2018 Jul 13.

Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1038/s41386-018-0151-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300565PMC
January 2019

Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2.

Alcohol Clin Exp Res 2018 12 25;42(12):2337-2348. Epub 2018 Oct 25.

Department of Psychiatry , Division of Human Genetics, VA CT Healthcare Center, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/acer.13890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317871PMC
December 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Dimensional Traits of Schizotypy Associated With Glycine Receptor GLRA1 Polymorphism: An Exploratory Candidate-Gene Association Study.

J Pers Disord 2018 06 31;32(3):421-432. Epub 2017 Jul 31.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, and James J. Peters Veterans Affairs Medical Center, Bronx, New York.

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http://dx.doi.org/10.1521/pedi_2017_31_303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856645PMC
June 2018

Joint Impact of Early Life Adversity and COMT Val158Met (rs4680) Genotypes on the Adult Cortisol Response to Psychological Stress.

Psychosom Med 2017 Jul/Aug;79(6):631-637

From the VA Medical Center (Lovallo, Sorocco); Department of Psychiatry and Behavioral Sciences (Lovallo, Cohoon), University of Oklahoma Health Sciences Center, Oklahoma City; Laboratory of Neurogenetics (Enoch, Hodgkinson, Goldman), National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland; Donald W. Reynolds Department of Geriatric Medicine (Sorocco), University of Oklahoma Health Sciences Center, Oklahoma City; Cognitive Science Research Center (Vincent), University of Oklahoma, Norman; Department of Psychiatry (Acheson), University of Texas Health Sciences Center at San Antonio; and Research Imaging Institute (Acheson), San Antonio, Texas.

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http://dx.doi.org/10.1097/PSY.0000000000000481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489380PMC
April 2018

Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1).

Am J Physiol Cell Physiol 2018 03 22;314(3):C289-C296. Epub 2017 Nov 22.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1152/ajpcell.00215.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415652PMC
March 2018

Concentrative Transport of Antifolates Mediated by the Proton-Coupled Folate Transporter (SLC46A1); Augmentation by a HEPES Buffer.

Mol Pharmacol 2018 03 11;93(3):208-215. Epub 2018 Jan 11.

Departments of Molecular Pharmacology (R.Z., M.N., S.A., I.D.G.), Medicine (R.Z., I.D.G.), and Dominick P. Purpura Department of Neuroscience (D.C.S.), Albert Einstein College of Medicine, Bronx, New York

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http://dx.doi.org/10.1124/mol.117.110445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801552PMC
March 2018

Effects on gene expression and behavior of untagged short tandem repeats: the case of arginine vasopressin receptor 1a (AVPR1a) and externalizing behaviors.

Transl Psychiatry 2018 03 27;8(1):72. Epub 2018 Mar 27.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, 20852, USA.

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http://dx.doi.org/10.1038/s41398-018-0120-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913313PMC
March 2018

Lower airway microbiota and mycobiota in children with severe asthma.

J Allergy Clin Immunol 2018 02 13;141(2):808-811.e7. Epub 2017 Oct 13.

Department of Pediatrics, Children's Hospital at Montefiore, Bronx, NY; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY.

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http://dx.doi.org/10.1016/j.jaci.2017.09.018DOI Listing
February 2018

Addiction Biomarkers: Dimensional Approaches to Understanding Addiction.

Trends Mol Med 2018 02 5;24(2):121-128. Epub 2018 Jan 5.

Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892, USA; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, 20852, USA.

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http://dx.doi.org/10.1016/j.molmed.2017.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233300PMC
February 2018

Severity of alcohol dependence is associated with the fatty acid amide hydrolase Pro129Thr missense variant.

Addict Biol 2018 01 1;23(1):474-484. Epub 2017 Feb 1.

Section on Human Psychopharmacology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/adb.12491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538894PMC
January 2018

DNA methylome variation in a perinatal nurse-visitation program that reduces child maltreatment: a 27-year follow-up.

Transl Psychiatry 2018 01 10;8(1):15. Epub 2018 Jan 10.

The Ludmer Centre for Neuroinformatics and Mental Health, Douglas Hospital Research Centre and Sackler Program for Epigenetics and Psychobiology, McGill University, Montreal, QC, H4H1R3, Canada.

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http://dx.doi.org/10.1038/s41398-017-0063-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802588PMC
January 2018

Noninfectious Enterocolitis as Initial Presentation of Chronic Granulomatous Disease.

Clin Pediatr (Phila) 2017 12 22;56(14):1353-1356. Epub 2016 Dec 22.

4 Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1177/0009922816684612DOI Listing
December 2017

Residues in the eighth transmembrane domain of the proton-coupled folate transporter (SLC46A1) play an important role in defining the aqueous translocation pathway and in folate substrate binding.

Biochim Biophys Acta Biomembr 2017 Nov 9;1859(11):2193-2202. Epub 2017 Aug 9.

Department of Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, United States; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2017.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624325PMC
November 2017

Regulation of Reduced Folate Carrier (RFC) by Vitamin D Receptor at the Blood-Brain Barrier.

Mol Pharm 2017 11 26;14(11):3848-3858. Epub 2017 Sep 26.

Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto , Toronto, Ontario M5S 3M2, Canada.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b00572DOI Listing
November 2017

Polygenic Risk Scores in Psychiatry.

Authors:
David Goldman

Biol Psychiatry 2017 11;82(10):698-699

Laboratory of Neurogenetics, Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2017.09.002DOI Listing
November 2017

Genetic studies of alcohol dependence in the context of the addiction cycle.

Neuropharmacology 2017 Aug 22;122:3-21. Epub 2017 Jan 22.

National Institutes of Health (NIH), National Institute on Alcohol Abuse and Alcoholism (NIAAA), Director NIAAA, 5635 Fishers Lane, Bethesda, MD 20852, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2017.01.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233301PMC
August 2017

Imaging Genetics and Genomics in Psychiatry: A Critical Review of Progress and Potential.

Biol Psychiatry 2017 08 13;82(3):165-175. Epub 2017 Jan 13.

Laboratory of Neurogenetics, Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.biopsych.2016.12.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505787PMC
August 2017

Addictions Neuroclinical Assessment: A reverse translational approach.

Neuropharmacology 2017 Aug 7;122:254-264. Epub 2017 Mar 7.

Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892, USA; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2017.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569299PMC
August 2017

Extracellular dopamine, acetylcholine, and activation of dopamine D1 and D2 receptors after selective breeding for cocaine self-administration in rats.

Psychopharmacology (Berl) 2017 Aug 26;234(16):2475-2487. Epub 2017 May 26.

Substance Abuse Research Laboratory, 151, Kansas City Veterans Affairs Medical Center, 4801 Linwood Boulevard, Kansas City, MO, 64128, USA.

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http://dx.doi.org/10.1007/s00213-017-4640-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538921PMC
August 2017

Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia.

Neuron 2017 Jul 6;95(2):341-356.e6. Epub 2017 Jul 6.

Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754189PMC
July 2017

Neuromodulation interventions for addictive disorders: challenges, promise, and roadmap for future research.

Brain 2017 May;140(5):1183-1203

Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/aww284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059187PMC
May 2017

Does MAOA increase susceptibility to prenatal stress in young children?

Neurotoxicol Teratol 2017 05 3;61:82-91. Epub 2017 Feb 3.

Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, 676 N Saint Clair, Suite 1000, Chicago, IL, 60611, USA; Institute for Policy Research, Northwestern University, 2040 Sheridan Road, Evanston, IL 60208, USA; Institute for Innovations in Developmental Sciences, Northwestern University, 633 N Saint Clair, 19th Floor, Chicago, IL, 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ntt.2017.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453809PMC
May 2017

Brain-derived neurotrophic factor Val66Met genotype modulates amygdala habituation.

Psychiatry Res Neuroimaging 2017 May 24;263:85-92. Epub 2017 Mar 24.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Mental Illness Research Education and Clinical Center, James J. Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA.

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http://dx.doi.org/10.1016/j.pscychresns.2017.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856456PMC
May 2017

Reply to: Neuroclinical Assessment of Addiction Needs to Incorporate Decision-Making Measures and Ecological Validity.

Biol Psychiatry 2017 04 30;81(7):e55. Epub 2016 Aug 30.

Office of the Clinical Director, Bethesda, Maryland; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.biopsych.2016.08.029DOI Listing
April 2017

Impact of posttranslational modifications of engineered cysteines on the substituted cysteine accessibility method: evidence for glutathionylation.

Am J Physiol Cell Physiol 2017 Apr 25;312(4):C517-C526. Epub 2017 Jan 25.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York; and

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http://dx.doi.org/10.1152/ajpcell.00350.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407019PMC
April 2017

The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption.

Mol Aspects Med 2017 02 21;53:57-72. Epub 2016 Sep 21.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2016.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253092PMC
February 2017

Dysfunctional tear syndrome: dry eye disease and associated tear film disorders - new strategies for diagnosis and treatment.

Curr Opin Ophthalmol 2017 Jan;27 Suppl 1:3-47

aYale University School of Medicine, New Haven bThe Eye Center of Southern Connecticut, Hamden, Connecticut cOhio State University, Columbus dComprehensive Eye Care of Central Ohio, Westerville, Ohio eHofstra Northwell School of Medicine, Hempstead fSouth Shore Eye Care, Wantagh, New York gFlorida Vision Institute, Jupiter hBascom Palmer Eye Institute, Florida International University, and Center for Excellence in Eye Care, Miami, Florida iVance Thompson Vision, Sioux Falls, South Dakota jNortheastern Eye Institute, Scranton kCommonwealth Medical College, Scranton, Pennsylvania lOphthalmology Consultants, St. Louis, Missouri mJules Stein Eye Institute, Los Angeles nWolstan & Goldberg Eye Associates, Torrance, California oPalm Beach Gardens, Florida pRush University Medical Center, Chicago qChicago Eye Specialists rUniversity of Chicago Hospitals, Chicago sJacksoneye, Lake Villa tMidwest Center for Sight, Des Plaines, Illinois uDuke Eye Center, Durham, North Carolina vChicago Cornea Consultants, Ltd, Hoffman Estates, Illinois wWashington University Department of Ophthalmology and Ophthalmology Associates, St. Louis, Missouri xNYU Langone Medical Center, New York, New York yTulane University School of Medicine, New Orleans, Louisiana zOphthalmic Consultants of Long Island, Lynbrook, New York aaThe Center for Ocular Surface Excellence of New Jersey, Woodland Park, New Jersey bbGeorgetown University Medical Center, George Washington University Medical Center, Washington, DC ccNew York Eye and Ear Infirmary of Mount Sinai and Eye Center of New York, New York, New York ddNVision EyeCenters of Newport Beach, Newport Beach, California eeUniversity of Maryland, Baltimore, Maryland ffAdvanced Vision Care, Century City, California ggKeck School of Medicine, University of Southern California, Los Angeles hhBowie Vision Institute, Bowie, Maryland iiUniversity of North Carolina and TLC Laser Eye Centers, Greensboro, North Carolina jjMercy Eye Specialists, Springfield, Missouri kkWake Forest University, Winston-Salem, North Carolina llStorm Eye Institute and Magill Vision Center, Medical University of South Carolina, Charleston mmClemson University, Mt. Pleasant, South Carolina nnUniversity of South Florida, Tampa ooThe Eye Institute of West Florida, Largo, Florida ppCleveland Eye Clinic, Clear Choice Custom LASIK Center, Brecksville, Ohio qqEastern Virginia Medical School and Virginia Eye Consultants, Norfolk, Virginia, USA *Mark S. Milner, Kenneth A. Beckman, and Jodi I. Luchs are co-chairs.

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http://dx.doi.org/10.1097/01.icu.0000512373.81749.b7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345890PMC
January 2017

Making Sense of Epigenetics.

Int J Neuropsychopharmacol 2016 11 3;19(11). Epub 2016 Dec 3.

Laboratory of Neurogenetics and Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland (Drs Schuebel, Gitik, and Goldman); Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany (Dr Domschke).

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http://dx.doi.org/10.1093/ijnp/pyw058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137275PMC
November 2016

Association of Superoxide Dismutase 2 (SOD2) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel.

Int J Neuropsychopharmacol 2016 Sep 21;19(9). Epub 2016 Sep 21.

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland (Drs Gitik, Srivastava, and Hodgkinson, Ms Shen, and Dr Goldman); Department of Radiology and Biomedical Imaging, University of California, San Francisco, California (Dr Meyerhoff); Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, California (Dr Meyerhoff).Current address (V.S.): Molecular Genetic Technology Program, School of Health Professions, MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.

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http://dx.doi.org/10.1093/ijnp/pyw033DOI Listing
September 2016

Cryptococcal Disease in HIV-Infected Children.

Curr Infect Dis Rep 2016 Sep;18(9):27

Division of Pediatric Infectious Diseases, Children's Hospital at Montefiore, The Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY, 10467, USA.

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September 2016

Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders.

Biol Psychiatry 2016 08 17;80(3):179-89. Epub 2015 Nov 17.

Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland; Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870153PMC
August 2016

The abundance of cis-acting loci leading to differential allele expression in F1 mice and their relationship to loci harboring genes affecting complex traits.

BMC Genomics 2016 08 11;17(1):620. Epub 2016 Aug 11.

Laboratory of Neurogenetics, National institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, 20852, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982227PMC
August 2016

Role of the tryptophan residues in proton-coupled folate transporter (PCFT-SLC46A1) function.

Am J Physiol Cell Physiol 2016 07 1;311(1):C150-7. Epub 2016 Jun 1.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967132PMC
July 2016

Effect of Functionally Significant Deiodinase Single Nucleotide Polymorphisms on Drinking Behavior in Alcohol Dependence: An Exploratory Investigation.

Alcohol Clin Exp Res 2015 Sep 24;39(9):1665-70. Epub 2015 Jul 24.

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology , National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland.

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September 2015

Identification of an Extracellular Gate for the Proton-coupled Folate Transporter (PCFT-SLC46A1) by Cysteine Cross-linking.

J Biol Chem 2016 Apr 16;291(15):8162-72. Epub 2016 Feb 16.

From the Departments of Molecular Pharmacology, Medicine,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825018PMC
April 2016

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

Authors:
Tae-Hwi Schwantes-An Juan Zhang Li-Shiun Chen Sarah M Hartz Robert C Culverhouse Xiangning Chen Hilary Coon Josef Frank Helen M Kamens Bettina Konte Leena Kovanen Antti Latvala Lisa N Legrand Brion S Maher Whitney E Melroy Elliot C Nelson Mark W Reid Jason D Robinson Pei-Hong Shen Bao-Zhu Yang Judy A Andrews Paul Aveyard Olga Beltcheva Sandra A Brown Dale S Cannon Sven Cichon Robin P Corley Norbert Dahmen Louisa Degenhardt Tatiana Foroud Wolfgang Gaebel Ina Giegling Stephen J Glatt Richard A Grucza Jill Hardin Annette M Hartmann Andrew C Heath Stefan Herms Colin A Hodgkinson Per Hoffmann Hyman Hops David Huizinga Marcus Ising Eric O Johnson Elaine Johnstone Radka P Kaneva Kenneth S Kendler Falk Kiefer Henry R Kranzler Ken S Krauter Orna Levran Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Nicholas G Martin Manuel Mattheisen Grant W Montgomery Bertram Müller-Myhsok Michael F Murphy Michael C Neale Momchil A Nikolov Denise Nishita Markus M Nöthen John Nurnberger Timo Partonen Michele L Pergadia Maureen Reynolds Monika Ridinger Richard J Rose Noora Rouvinen-Lagerström Norbert Scherbaum Christine Schmäl Michael Soyka Michael C Stallings Michael Steffens Jens Treutlein Ming Tsuang Tamara L Wall Norbert Wodarz Vadim Yuferov Peter Zill Andrew W Bergen Jingchun Chen Paul M Cinciripini Howard J Edenberg Marissa A Ehringer Robert E Ferrell Joel Gelernter David Goldman John K Hewitt Christian J Hopfer William G Iacono Jaakko Kaprio Mary Jeanne Kreek Ivo M Kremensky Pamela A F Madden Matt McGue Marcus R Munafò Robert A Philibert Marcella Rietschel Alec Roy Dan Rujescu Sirkku T Saarikoski Gary E Swan Alexandre A Todorov Michael M Vanyukov Robert B Weiss Laura J Bierut Nancy L Saccone

Behav Genet 2016 Mar 21;46(2):151-69. Epub 2015 Sep 21.

Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752855PMC
March 2016

February consultation #8.

Authors:
David A Goldman

J Cataract Refract Surg 2016 Feb;42(2):344

Palm Beach Gardens, Florida, USA.

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February 2016

Heterogeneity of lower airway inflammation in children with severe-persistent asthma.

Pediatr Pulmonol 2015 Dec 4;50(12):1200-4. Epub 2015 Mar 4.

Department of Pediatrics, Kravis Children's Hospital, Icahn School of Medicine at Mount Sinai, New York City, New York.

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December 2015

Effect of Functionally Significant Deiodinase Single Nucleotide Polymorphisms on Drinking Behavior in Alcohol Dependence: An Exploratory Investigation.

Alcohol Clin Exp Res 2015 Sep 24;39(9):1665-70. Epub 2015 Jul 24.

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology , National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland.

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September 2015

America's Cannabis Experiment.

Authors:
David Goldman

JAMA Psychiatry 2015 Oct;72(10):969-70

Laboratory of Neurogenetics, Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.1332DOI Listing
October 2015

A conversation with Susan Band Horwitz.

Annu Rev Pharmacol Toxicol 2015 ;55:1-9

Department of Molecular Pharmacology and.

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September 2015

Effect of Functionally Significant Deiodinase Single Nucleotide Polymorphisms on Drinking Behavior in Alcohol Dependence: An Exploratory Investigation.

Alcohol Clin Exp Res 2015 Sep 24;39(9):1665-70. Epub 2015 Jul 24.

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology , National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland.

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September 2015

Tetanus After Vaccine Refusal and an Opportunity for the Pediatric Infectious Diseases Specialist.

Clin Pediatr (Phila) 2015 Jun 6;54(6):513-6. Epub 2014 May 6.

Albert Einstein College of Medicine, Bronx, NY, USA.

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June 2015

Determinants of the activities of antifolates delivered into cells by folate-receptor-mediated endocytosis.

Cancer Chemother Pharmacol 2015 Jun 7;75(6):1163-73. Epub 2015 Apr 7.

Departments of Medicine, Albert Einstein College of Medicine, Chanin 628, 1300 Morris Park Ave, Bronx, NY, 10461, USA,

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http://dx.doi.org/10.1007/s00280-015-2733-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442060PMC
June 2015

Gene expression in the addicted brain.

Int Rev Neurobiol 2014 ;116:251-73

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/B978-0-12-801105-8.00010-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427035PMC
May 2015

Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms.

Hepatology 2015 May 17;61(5):1615-26. Epub 2015 Feb 17.

Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406817PMC
May 2015

Identification of Tyr residues that enhance folate substrate binding and constrain oscillation of the proton-coupled folate transporter (PCFT-SLC46A1).

Am J Physiol Cell Physiol 2015 Apr 21;308(8):C631-41. Epub 2015 Jan 21.

Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York; Department of Medicine, Albert Einstein College of Medicine, Bronx, New York;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398847PMC
April 2015

DNA methylation in the medial prefrontal cortex regulates alcohol-induced behavior and plasticity.

J Neurosci 2015 Apr;35(15):6153-64

Department of Clinical and Experimental Medicine, Division of Cell Biology, Faculty of Health Sciences, Linköping University, SE-581 85 Linköping, Sweden, Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-1108.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397609PMC
April 2015

Effects of the Mu opioid receptor polymorphism (OPRM1 A118G) on pain regulation, placebo effects and associated personality trait measures.

Neuropsychopharmacology 2015 Mar 13;40(4):957-65. Epub 2014 Oct 13.

1] Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA [2] Department of Radiology, Medical School, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1038/npp.2014.272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330509PMC
March 2015

Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition.

Nat Commun 2015 Feb 11;6:6139. Epub 2015 Feb 11.

1] Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts 02139, USA [3] Division of Biomedical Engineering, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA [4] Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339891PMC
February 2015

Genomics of impulsivity: integrating genes and neuroscience.

Authors:
David Goldman

Nebr Symp Motiv 2014 ;61:129-39

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December 2014

The missing heritability of behavior: the search continues.

Authors:
David Goldman

Psychophysiology 2014 Dec;51(12):1327-8

Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health (NIH), Rockville, Maryland, USA.

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http://dx.doi.org/10.1111/psyp.12362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427030PMC
December 2014

Evidence of MAOA genotype involvement in spatial ability in males.

Behav Brain Res 2014 Jul 23;267:106-10. Epub 2014 Mar 23.

Section on Developmental and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548810PMC
July 2014

Management of Fever in postpneumococcal vaccine era: comparison of management practices by pediatric emergency medicine and general emergency medicine physicians.

Emerg Med Int 2014 1;2014:702053. Epub 2014 Jun 1.

Division of Pediatric Emergency Medicine, Children's Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY 10467, USA ; Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY 10467, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058597PMC
July 2014

Differential impact of serotonin transporter activity on temperament and behavior in persons with a family history of alcoholism in the Oklahoma Family Health Patterns Project.

Alcohol Clin Exp Res 2014 Jun 5;38(6):1575-81. Epub 2014 May 5.

Department of Psychiatry and Behavioral Sciences , University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Behavioral Sciences Laboratories , Veterans Affairs Medical Center, Oklahoma City, Oklahoma.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047646PMC
June 2014

The impact of 5-formyltetrahydrofolate on the anti-tumor activity of pralatrexate, as compared to methotrexate, in HeLa cells in vitro.

Cancer Chemother Pharmacol 2014 May 29;73(5):1055-62. Epub 2014 Mar 29.

Department of Molecular Pharmacology, Albert Einstein Cancer Center, Albert Einstein College of Medicine, Chanin 2, 1300 Morris Park Avenue, Bronx, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018754PMC
May 2014

Valence-specific effects of BDNF Val66Met polymorphism on dopaminergic stress and reward processing in humans.

J Neurosci 2014 Apr;34(17):5874-81

Department of Psychiatry and Molecular and Behavioral Neuroscience Institute, Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109, Research Institute on Health Sciences-Institut Universitari d'Investigació en Ciencies de la Salut (IUNICS), Palma de Mallorca 07122, Spain, College of Dental Medicine, Columbia University, New York, New York 10032, and National Institute of Alcohol Abuse and Alcoholism, Rockville, Maryland 20852.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2152-13.2
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996214PMC
April 2014