David Geho

David Geho

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David Geho

David Geho

Publications by authors named "David Geho"

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Protein pathway analysis in Clinical Proteomics using protein microarrays.

Drug Discov Today Technol 2005 ;2(4):353-9

The Center for Applied Proteomics and Molecular Medicine, George Mason University, 10900 University Blvd MS 4E3, Discovery Hall Room 182, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1016/j.ddtec.2005.11.008DOI Listing
July 2014

RG7212 anti-TWEAK mAb inhibits tumor growth through inhibition of tumor cell proliferation and survival signaling and by enhancing the host antitumor immune response.

Clin Cancer Res 2013 Oct 23;19(20):5686-98. Epub 2013 Aug 23.

Authors' Affiliations: Roche Pharma Research and Early Development, Nutley, New Jersey; Roche Diagnostics GmbH, Pharma Research & Early Development, Nonnenwald, Penzberg, Germany; and Roche Pharma Research and Early Development, Roche Glycart AG, Schlieren, Switzerland.

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http://clincancerres.aacrjournals.org/content/early/2013/10/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-13-0405DOI Listing
October 2013

Fluorescence-based analysis of cellular protein lysate arrays using quantum dots.

Methods Mol Biol 2007 ;374:229-37

Center for Applied Proteomics and Molecular Medicine, Department of Molecular and Microbiology, George Mason University, Manassas, Virginia, USA.

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http://dx.doi.org/10.1385/1-59745-369-2:229DOI Listing
December 2007

Laser-capture microdissection.

Nat Protoc 2006 ;1(2):586-603

Center for Applied Proteomics and Molecular Medicine, George Mason University, 10900 University Blvd. MS 4E3, Manassas, Virginia, USA.

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http://dx.doi.org/10.1038/nprot.2006.85DOI Listing
September 2007

Physicochemically modified silicon as a substrate for protein microarrays.

Biomaterials 2007 Jan 20;28(3):550-8. Epub 2006 Sep 20.

Comprehensive Cancer Center, The Ohio State University, 473 W 12th Ave, #326 Columbus, OH 43210, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2006.08.051DOI Listing
January 2007

Multispectral imaging of clinically relevant cellular targets in tonsil and lymphoid tissue using semiconductor quantum dots.

Mod Pathol 2006 Sep 16;19(9):1181-91. Epub 2006 Jun 16.

Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1038/modpathol.3800628DOI Listing
September 2006

Role of proteomics in personalized medicine.

Per Med 2006 Aug;3(3):223-226

George Mason University, Center for Applied Proteomics and Molecular Medicine, Manassas, VA 20110, USA.

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http://dx.doi.org/10.2217/17410541.3.3.223DOI Listing
August 2006

Fractionation of serum components using nanoporous substrates.

Bioconjug Chem 2006 May-Jun;17(3):654-61

Laboratory of Pathology, FDA-NCI Clinical Proteomics Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1021/bc0503364DOI Listing
July 2006

Nanoparticles: potential biomarker harvesters.

Curr Opin Chem Biol 2006 Feb 18;10(1):56-61. Epub 2006 Jan 18.

Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA.

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http://dx.doi.org/10.1016/j.cbpa.2006.01.003DOI Listing
February 2006

The amplified peptidome: the new treasure chest of candidate biomarkers.

Curr Opin Chem Biol 2006 Feb 18;10(1):50-5. Epub 2006 Jan 18.

Center for Applied Proteomics and Molecular Medicine, George Mason University, 10900 University Boulevard, MS 4E3, Manassas, VA 20110, USA.

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http://dx.doi.org/10.1016/j.cbpa.2006.01.008DOI Listing
February 2006

Intestinal disease in Hermansky-Pudlak syndrome: occurrence of colitis and relation to genotype.

Clin Gastroenterol Hepatol 2006 Jan;4(1):73-80

National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-1851, USA.

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http://dx.doi.org/10.1016/s1542-3565(05)00858-xDOI Listing
January 2006

Pegylated, steptavidin-conjugated quantum dots are effective detection elements for reverse-phase protein microarrays.

Bioconjug Chem 2005 May-Jun;16(3):559-66

FDA-NCI Clinical Proteomics Program, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1021/bc0497113DOI Listing
September 2005

Physiological mechanisms of tumor-cell invasion and migration.

Physiology (Bethesda) 2005 Jun;20:194-200

Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1152/physiol.00009.2005DOI Listing
June 2005

Pathology of the future: molecular profiling for targeted therapy.

Cancer Invest 2005 ;23(1):36-46

National Cancer Institute, Laboratory of Pathology, Bethesda, Maryland, USA.

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April 2005

Opportunities for nanotechnology-based innovation in tissue proteomics.

Biomed Microdevices 2004 Sep;6(3):231-9

FDA-NCI Clinical Proteomics Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1023/B:BMMD.0000042053.51016.b4DOI Listing
September 2004

Serum proteomics in cancer diagnosis and management.

Annu Rev Med 2004 ;55:97-112

Laboratory of Pathology, National Cancer Institute, Center for Cancer Research, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1146/annurev.med.55.091902.105237DOI Listing
May 2004

Fibronectin-based masking molecule blocks platelet adhesion.

Bioconjug Chem 2003 Jul-Aug;14(4):703-6

Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://pubs.acs.org/doi/abs/10.1021/bc034037v
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http://dx.doi.org/10.1021/bc034037vDOI Listing
March 2004

Blasting into the microworld of tissue proteomics: a new window on cancer.

Clin Cancer Res 2004 Feb;10(3):825-7

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Rm 2A33, 10 Center Drive, Building 10, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.ccr-1223-3DOI Listing
February 2004

Protein microarrays: meeting analytical challenges for clinical applications.

Cancer Cell 2003 Apr;3(4):317-25

FDA-NCI Clinical Proteomics Program, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/s1535-6108(03)00086-2DOI Listing
April 2003

Lipid length controls antigen entry into endosomal and nonendosomal pathways for CD1b presentation.

Nat Immunol 2002 May 8;3(5):435-42. Epub 2002 Apr 8.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1038/ni780DOI Listing
May 2002