David G McFadden

David G McFadden

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David G McFadden

David G McFadden

Publications by authors named "David G McFadden"

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17Publications

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Engineering Forward Genetics into Cultured Cancer Cells for Chemical Target Identification.

Cell Chem Biol 2019 Sep 11;26(9):1315-1321.e3. Epub 2019 Jul 11.

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.06.006DOI Listing
September 2019

Short Review: Genomic Alterations in Hürthle Cell Carcinoma.

Thyroid 2019 Apr;29(4):471-479

2 Department of Internal Medicine, Division of Endocrinology, Department of Biochemistry, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas.

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https://www.liebertpub.com/doi/10.1089/thy.2019.0088
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http://dx.doi.org/10.1089/thy.2019.0088DOI Listing
April 2019

Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma.

Cancer Cell 2018 08;34(2):242-255.e5

Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Thyroid Unit, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Internal Medicine, Division of Endocrinology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121811PMC
August 2018

Thyroid cancer.

Lancet 2016 12 27;388(10061):2783-2795. Epub 2016 May 27.

Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.1016/S0140-6736(16)30172-6DOI Listing
December 2016

The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung.

J Thorac Oncol 2015 Apr;10(4):553-64

*Hamon Center for Therapeutic Oncology Research and Department of Pathology, UT Southwestern Medical Center, Dallas, TX; †Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX; ‡Cancer Genomics Centre, The Netherlands Cancer Institute, Amsterdam, The Netherlands; §Departments of Pediatrics and Genetics, Stanford University, Stanford, CA; ‖Center for Cancer Research, National Cancer Institute, Bethesda, MD; ¶Division of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA; #David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142; **Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY; and ††Departementd'Anatomie et Cytologie Pathologiques, INSERM Unit 823, Centre Hospitalier Universitaire Albert Michallon, and Institut Albert Bonniot University, Grenoble, France.

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http://dx.doi.org/10.1097/JTO.0000000000000459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523224PMC
April 2015

Redifferentiation of iodine-refractory BRAF V600E-mutant metastatic papillary thyroid cancer with dabrafenib.

Clin Cancer Res 2015 Mar 30;21(5):1028-35. Epub 2014 Dec 30.

Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2915DOI Listing
March 2015

Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma.

J Clin Endocrinol Metab 2014 Nov 22;99(11):E2457-62. Epub 2014 Aug 22.

Thyroid Unit (D.G.M., S.E.D., G.H.D.), Department of Medicine, Department of Pathology (D.D.-S., P.M.S., K.D.L., Z.Z., L.L., A.J.I.), and Department of Surgery (C.L.), Cancer Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.

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http://dx.doi.org/10.1210/jc.2014-2611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223441PMC
November 2014

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer.

Proc Natl Acad Sci U S A 2014 Apr 7;111(16):E1600-9. Epub 2014 Apr 7.

Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.

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http://dx.doi.org/10.1073/pnas.1404357111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000830PMC
April 2014

Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.

Cell 2014 Mar;156(6):1298-1311

Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.02.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040459PMC
March 2014

The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner.

Development 2005 Jan 2;132(1):189-201. Epub 2004 Dec 2.

Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390-9148, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.01562
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http://dx.doi.org/10.1242/dev.01562DOI Listing
January 2005

Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme.

Dev Biol 2003 Mar;255(2):230-7

Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, , Dallas, TX 75390-9104, USA.

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http://dx.doi.org/10.1016/s0012-1606(02)00097-0DOI Listing
March 2003

Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding.

Development 2002 Jul;129(13):3077-88

Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9148, USA.

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July 2002

Heart development: learning from mistakes.

Curr Opin Genet Dev 2002 Jun;12(3):328-35

Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, Texas 75390-9148, USA.

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http://dx.doi.org/10.1016/s0959-437x(02)00306-4DOI Listing
June 2002