David G Maloney

David G Maloney

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David G Maloney

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Patient-Reported Neuropsychiatric Outcomes of Long-Term Survivors after Chimeric Antigen Receptor-T Cell Therapy.

Biol Blood Marrow Transplant 2019 Oct 9. Epub 2019 Oct 9.

Division of Clinical Research; Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.09.037DOI Listing
October 2019

Late Events after Treatment with CD19-Targeted Chimeric Antigen Receptor Modified T Cells.

Biol Blood Marrow Transplant 2019 Aug 13. Epub 2019 Aug 13.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.08.003DOI Listing
August 2019

Second allogeneic hematopoietic cell transplantation for relapse after first allografts.

Leuk Lymphoma 2019 Jul 22;60(7):1758-1766. Epub 2019 Jan 22.

c Clinical Research Division , Fred Hutchinson Cancer Research Center , Seattle , WA , USA.

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http://dx.doi.org/10.1080/10428194.2018.1542149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594865PMC
July 2019

Outcomes of Patients With Therapy-Related MDS After Chemoimmunotherapy for Chronic Lymphocytic Leukemia Compared With Patients With De Novo MDS: A Single-Institution Experience.

Clin Lymphoma Myeloma Leuk 2019 Jun 11;19(6):390-395. Epub 2019 Mar 11.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; Division of Medical Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, WA. Electronic address:

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http://dx.doi.org/10.1016/j.clml.2019.03.003DOI Listing
June 2019

Anti-CD19 CAR T cell therapy for lymphoma - off to the races!

Authors:
David G Maloney

Nat Rev Clin Oncol 2019 05;16(5):279-280

Bezos Family Immunotherapy Clinic, Fred Hutchinson Cancer Research Center and the University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41571-019-0183-7DOI Listing
May 2019

Not so crystal clear: observations from a case of crystalline arthritis with cytokine release syndrome (CRS) after chimeric antigen receptor (CAR)-T cell therapy.

Bone Marrow Transplant 2019 Apr 5;54(4):632-634. Epub 2018 Oct 5.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41409-018-0357-4
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http://dx.doi.org/10.1038/s41409-018-0357-4DOI Listing
April 2019

Management of cytokine release syndrome and neurotoxicity in chimeric antigen receptor (CAR) T cell therapy.

Expert Rev Hematol 2019 Mar 18;12(3):195-205. Epub 2019 Mar 18.

a Division of Medical Oncology, Department of Internal Medicine , University of Washington School of Medicine , Seattle , WA , USA.

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http://dx.doi.org/10.1080/17474086.2019.1585238DOI Listing
March 2019

Long-Term Follow-Up of Y-Ibritumomab Tiuxetan, Fludarabine, and Total Body Irradiation-Based Nonmyeloablative Allogeneic Transplant Conditioning for Persistent High-Risk B Cell Lymphoma.

Biol Blood Marrow Transplant 2018 11 3;24(11):2211-2215. Epub 2018 Jul 3.

Department of Medicine, Division of Medical Oncology, University of Washington, Seattle, Washington; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791183038
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http://dx.doi.org/10.1016/j.bbmt.2018.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251312PMC
November 2018

Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'.

Nat Rev Clin Oncol 2018 04 13;15(4):218. Epub 2018 Feb 13.

Department of Pediatrics and The Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/nrclinonc.2018.19DOI Listing
April 2018

Continued Excellent Outcomes in Previously Untreated Patients With Follicular Lymphoma After Treatment With CHOP Plus Rituximab or CHOP Plus I-Tositumomab: Long-Term Follow-Up of Phase III Randomized Study SWOG-S0016.

J Clin Oncol 2018 03 22;36(7):697-703. Epub 2018 Jan 22.

Mazyar Shadman, Ajay K. Gopal, David G. Maloney, and Oliver W. Press, University of Washington and Fred Hutchinson Cancer Research Center; Hongli Li and Michael LeBlanc, SWOG Statistical Center, Seattle, WA; Lisa Rimsza, Mayo Clinic Arizona, Scottsdale; Catherine M. Spier, University of Arizona, Tucson, AZ; John P. Leonard, Weill Cornell Medical College, New York; Jonathan W. Friedberg, Wilmot Cancer Institute, University of Rochester, Rochester, NY; Mark S. Kaminski, University of Michigan Health System, Ann Arbor, MI; Rita M. Braziel, Oregon Health & Science University, Portland, OR; Bruce D. Cheson, Lombardi Comprehensive Cancer Center, Georgetown University Hospital, Washington, DC; Shaker Dakhil, University of Kansas School of Medicine-Wichita, Wichita, KS; Sonali M. Smith, University of Chicago Medicine, Chicago, IL; and Richard I. Fisher, Fox Chase Cancer Center and Temple University School of Medicine, Philadelphia, PA.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.5083
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http://dx.doi.org/10.1200/JCO.2017.74.5083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553811PMC
March 2018

Reversal of Low Donor Chimerism after Hematopoietic Cell Transplantation Using Pentostatin and Donor Lymphocyte Infusion: A Prospective Phase II Multicenter Trial.

Biol Blood Marrow Transplant 2018 02 12;24(2):308-313. Epub 2017 Oct 12.

Clinical Research Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767527PMC
February 2018

Absence of Replication-Competent Lentivirus in the Clinic: Analysis of Infused T Cell Products.

Mol Ther 2018 01 12;26(1):280-288. Epub 2017 Sep 12.

Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5156, USA.

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http://dx.doi.org/10.1016/j.ymthe.2017.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762981PMC
January 2018

Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor-Modified T Cells After Failure of Ibrutinib.

J Clin Oncol 2017 Sep 17;35(26):3010-3020. Epub 2017 Jul 17.

Cameron J. Turtle, Kevin A. Hay, Laïla-Aïcha Hanafi, Shelly Heimfeld, Stanley R. Riddell, and David G. Maloney, Fred Hutchinson Cancer Research Center; Cameron J. Turtle, Sindhu Cherian, Xueyan Chen, Brent Wood, Stanley R. Riddell, and David G. Maloney, University of Washington; Daniel Li, Juno Therapeutics, Seattle, WA; and Arletta Lozanski and John C. Byrd, The Ohio State University, Columbus, OH.

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http://dx.doi.org/10.1200/JCO.2017.72.8519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590803PMC
September 2017

Immunotherapy in lymphoma.

Hematol Oncol 2017 Jun;35 Suppl 1:88-91

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1002/hon.2408DOI Listing
June 2017

Beyond RCHOP: A Blueprint for Diffuse Large B Cell Lymphoma Research.

J Natl Cancer Inst 2016 12 16;108(12). Epub 2016 Dec 16.

Department of Medicine, Mayo Clinic, Rochester, MN (GSN); Department of Internal Medicine, Ohio State University, Columbus, OH (KAB); Department of Medicine, Oncology Division, Washington University, St. Louis, MO (BSK); Wilmot Cancer Center and Division of Hematology/Oncology, University of Rochester, Rochester, NY (JWF); Coordinating Center for Clinical Trials (LB), Division of Cancer Treatment and Diagnosis (RFL), and Center for Cancer Research (WHW), National Cancer Institute, National Institute of Health, Bethesda, MD; Division of Oncology, University of Washington, Seattle WA (DGM); British Colombia Cancer Agency, Vancouver, BC (LHS); Department of Medicine, University of Virginia, Charlottesville, VA (MEW); Department of Medicine, Weil Cornell University, New York, NY (JPL); Department of Medicine, University of Chicago, Chicago, IL (SMS).

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http://dx.doi.org/10.1093/jnci/djw257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080361PMC
December 2016

Comorbidities, Alcohol Use Disorder, and Age Predict Outcomes after Autologous Hematopoietic Cell Transplantation for Lymphoma.

Biol Blood Marrow Transplant 2016 09 14;22(9):1582-1587. Epub 2016 Jun 14.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2016.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981519PMC
September 2016

Clinical trials of CD19-targeted CAR-modified T cell therapy; a complex and varied landscape.

Expert Rev Hematol 2016 08 4;9(8):719-21. Epub 2016 Jul 4.

a Clinical Research Division , Fred Hutchinson Cancer Research Center , Seattle , WA , USA.

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https://www.tandfonline.com/doi/full/10.1080/17474086.2016.1
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http://dx.doi.org/10.1080/17474086.2016.1203251DOI Listing
August 2016

Preserved Activity of CD20-Specific Chimeric Antigen Receptor-Expressing T Cells in the Presence of Rituximab.

Cancer Immunol Res 2016 06 21;4(6):509-19. Epub 2016 Apr 21.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891234PMC
June 2016

Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy.

Blood 2016 05 23;127(20):2406-10. Epub 2016 Feb 23.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; and Department of Medicine, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1182/blood-2015-08-665547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874221PMC
May 2016

Low Serum Vitamin D Levels Are Associated With Inferior Survival in Follicular Lymphoma: A Prospective Evaluation in SWOG and LYSA Studies.

J Clin Oncol 2015 May 30;33(13):1482-90. Epub 2015 Mar 30.

Jennifer L. Kelly and Jonathan W. Friedberg, James P. Wilmot Cancer Center, University of Rochester School of Medicine and Dentistry, Rochester, NY; Gilles Salles, Hospices Civils de Lyon, Université Claude Bernard Lyon-1, Pierre Benite; Pauline Brice, Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Paris; Olivier Casasnovas, Centre Hospitalo-Universitaire de Dijon, Dijon; Pierre Soubeyran, Institut Bergonié and Université Victor Segalen Bordeaux 2, Bordeaux; Corinne Haioun, Assistance Publique-Hôpitaux de Paris, Hôpital Henri Mondor, Créteil; Luc Xerri, Institut Paoli Calmettes, Marseille; Hervé Tilly, Centre Henri Becquerel, Rouen, France; Bryan Goldman, Oliver Press, and Michael LeBlanc, SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, WA; Richard I. Fisher, Fox Chase Cancer Center, Temple University School of Medicine, Philadelphia, PA; and Lisa Rimsza, University of Arizona, Tucson, AZ.

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http://jco.ascopubs.org/content/early/2015/03/30/JCO.2014.57
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.57.5092
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http://dx.doi.org/10.1200/JCO.2014.57.5092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404425PMC
May 2015

Long-term outcomes of patients with persistent indolent B cell malignancies undergoing nonmyeloablative allogeneic transplantation.

Biol Blood Marrow Transplant 2015 Feb 1;21(2):281-7. Epub 2014 Nov 1.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408880PMC
February 2015

Impact of donor age on outcome after allogeneic hematopoietic cell transplantation.

Biol Blood Marrow Transplant 2015 Jan 30;21(1):105-12. Epub 2014 Sep 30.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; Division of Oncology, University of Washington, School of Medicine, Seattle, Washington. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10838791140060
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http://dx.doi.org/10.1016/j.bbmt.2014.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286386PMC
January 2015

90Y-ibritumomab tiuxetan therapy in allogeneic transplantation in B-cell lymphoma with extensive marrow involvement and chronic lymphocytic leukemia: utility of pretransplantation biodistribution.

Nucl Med Commun 2014 Nov;35(11):1132-42

Departments of aRadiology bMedicine, Division of Medical Oncology, University of Washington Medical Center cClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington dDepartment of Radiology, Harvard Medical School, MGH Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MNM.0000000000000172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169733PMC
November 2014

Comorbidity-age index: a clinical measure of biologic age before allogeneic hematopoietic cell transplantation.

J Clin Oncol 2014 Oct 25;32(29):3249-56. Epub 2014 Aug 25.

Mohamed L. Sorror, Rainer F. Storb, Brenda M. Sandmaier, Fabiana Ostronoff, H. Joachim Deeg, Karen L. Syrjala, Elihu Estey, David G. Maloney, Frederick R. Appelbaum, Paul J. Martin, and Barry E. Storer, Fred Hutchinson Cancer Research Center; Mohamed L. Sorror, Rainer F. Storb, Brenda M. Sandmaier, Fabiana Ostronoff, H. Joachim Deeg, Karen L. Syrjala, Elihu Estey, David G. Maloney, Frederick R. Appelbaum, and Paul J. Martin, University of Washington School of Medicine; Barry E. Storer, University of Washington School of Public Health, Seattle, WA; Smita Bhatia, City of Hope School of Medicine, Duarte, CA; Richard T. Maziarz, Center for Hematologic Malignancies, Oregon Health & Science University Knight Cancer Institute and School of Medicine, Portland, OR; Michael A. Pulsipher, University of Utah School of Medicine and Primary Children's Medical Center, Huntsman Cancer Institute, Salt Lake City, UT; and Michael B. Maris, Colorado Blood Cancer Institute School of Medicine, Denver, CO.

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http://dx.doi.org/10.1200/JCO.2013.53.8157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178523PMC
October 2014

Pretransplant comorbidities predict severity of acute graft-versus-host disease and subsequent mortality.

Blood 2014 Jul 5;124(2):287-95. Epub 2014 May 5.

Clinical Statistics Program, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; and Department of Biostatistics, University of Washington School of Public Health, Seattle, WA.

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http://dx.doi.org/10.1182/blood-2014-01-550566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093684PMC
July 2014

Myeloablative I-131-tositumomab with escalating doses of fludarabine and autologous hematopoietic transplantation for adults age ≥ 60 years with B cell lymphoma.

Biol Blood Marrow Transplant 2014 Jun 12;20(6):770-5. Epub 2014 Feb 12.

Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, Washington; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1016/j.bbmt.2014.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019701PMC
June 2014

Autologous or reduced-intensity conditioning allogeneic hematopoietic cell transplantation for chemotherapy-sensitive mantle-cell lymphoma: analysis of transplantation timing and modality.

J Clin Oncol 2014 Feb 16;32(4):273-81. Epub 2013 Dec 16.

Timothy S. Fenske and Mehdi Hamadani, Medical College of Wisconsin; Mei-Jie Zhang, Jeanette Carreras, and Parameswaran N. Hari, Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI; Ernesto Ayala, H. Lee Moffitt Cancer Center and Research Institute, Tampa; Baldeep M. Wirk, Shands Healthcare and University of Florida, Gainesville, FL; Linda J. Burns, University of Minnesota Medical Center, Fairview, Minneapolis; David J. Inwards, Mayo Clinic Rochester, Rochester, MN; Amanda Cashen, Barnes Jewish Hospital, Washington University School of Medicine, St. Louis, MO; Luciano J. Costa, Medical University of South Carolina, Charleston, SC; César O. Freytes, South Texas Veterans Health Care System and University of Texas Health Science Center, San Antonio, TX; Robert P. Gale, Imperial College; Silvia Montoto, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom; Leona A. Holmberg and David G. Maloney, Fred Hutchinson Cancer Research Center, Seattle, WA; Hillard M. Lazarus, Seidman Cancer Center, University Hospitals Case Medical Center, Cleveland, OH; Richard T. Maziarz, Oregon Health and Science University, Portland, OR; Reinhold Munker, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA; Miguel-Angel Perales, Memorial Sloan-Kettering Cancer Center, New York, NY; David A. Rizzieri, Duke University Medical Center, Durham, NC; Harry C. Schouten, Academische Ziekenhuis Maastricht, Maastricht, the Netherlands; Sonali M. Smith, University of Chicago Hospitals, Chicago, IL; Edmund K. Waller, Emory University Hospital, Atlanta, GA; and Ginna G. Laport, Stanford Hospital and Clinics, Stanford, CA.

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http://dx.doi.org/10.1200/JCO.2013.49.2454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897255PMC
February 2014

A comparative analysis of prognostic factor models for follicular lymphoma based on a phase III trial of CHOP-rituximab versus CHOP + 131iodine--tositumomab.

Clin Cancer Res 2013 Dec 15;19(23):6624-32. Epub 2013 Oct 15.

Authors' Affiliations: Clinical Research Division; SWOG Statistical Center, Fred Hutchinson Cancer Research Center; Medical Oncology, University of Washington Medical Center, Seattle, Washington; Department of Pathology; Arizona Cancer Center, University of Arizona, Tucson, Arizona; James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester; Roswell Park Cancer Institute, Buffalo, New York; Cancer and Leukemia Group B; University of Michigan, Ann Arbor, Michigan; Department of Pathology, Oregon Health and Science University, Portland, Oregon; Georgetown University Hospital, Washington; Wichita Community Clinical Oncology Program, Wichita, Kansas; and Fox Chase Cancer Center-Temple Health, Temple University, Philadelphia PA.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872052PMC
December 2013

Anti-CD20 antibody therapy for B-cell lymphomas.

Authors:
David G Maloney

N Engl J Med 2012 May;366(21):2008-16

Fred Hutchinson Cancer Research Center and the University of Washington, Seattle, WA 98104-1029, USA.

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http://dx.doi.org/10.1056/NEJMct1114348DOI Listing
May 2012

Decreased serum albumin as a biomarker for severe acute graft-versus-host disease after reduced-intensity allogeneic hematopoietic cell transplantation.

Biol Blood Marrow Transplant 2011 Nov 30;17(11):1594-601. Epub 2011 Jul 30.

Clinical Research Division, Fred Hutchinson Cancer Research Center and University of Washington Medical Center, 1100Fairview Ave. N, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/j.bbmt.2011.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203323PMC
November 2011

The role of autologous and allogeneic hematopoietic stem cell transplantation for Hodgkin lymphoma.

J Natl Compr Canc Netw 2011 Sep;9(9):1060-71

Fred Hutchinson Cancer Research Center, Seattle, Washington 98104-1029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207964PMC
http://dx.doi.org/10.6004/jnccn.2011.0087DOI Listing
September 2011

Identification of MAGE-C1 (CT-7) epitopes for T-cell therapy of multiple myeloma.

Cancer Immunol Immunother 2011 Jul 3;60(7):985-97. Epub 2011 Apr 3.

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1007/s00262-011-1009-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183483PMC
July 2011

Rituximab resistance.

Best Pract Res Clin Haematol 2011 Jun 13;24(2):203-16. Epub 2011 Apr 13.

Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, D1-100, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/j.beha.2011.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113665PMC
June 2011

Stem cell transplantation for indolent lymphoma and chronic lymphocytic leukemia.

Biol Blood Marrow Transplant 2011 Jan;17(1 Suppl):S63-70

Barts and The London School of Medicine, London, United Kingdom.

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http://dx.doi.org/10.1016/j.bbmt.2010.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392079PMC
January 2011