Publications by authors named "David G Huntsman"

99Publications

Rare promoter 1B variants in gastric cancer kindreds unselected for fundic gland polyposis.

Gut 2020 Sep 7. Epub 2020 Sep 7.

Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada

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http://dx.doi.org/10.1136/gutjnl-2020-321990DOI Listing
September 2020

The Pathognomonic FOXL2 C134W Mutation Alters DNA-Binding Specificity.

Cancer Res 2020 Sep 8;80(17):3480-3491. Epub 2020 Jul 8.

Department of Microbiology and Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-20-0104DOI Listing
September 2020

Clinical and pathological associations of PTEN expression in ovarian cancer: a multicentre study from the Ovarian Tumour Tissue Analysis Consortium.

Authors:
Filipe Correia Martins Dominique-Laurent Couturier Anna Paterson Anthony N Karnezis Christine Chow Tayyebeh M Nazeran Adekunle Odunsi Aleksandra Gentry-Maharaj Aleksandra Vrvilo Alexander Hein Aline Talhouk Ana Osorio Andreas D Hartkopf Angela Brooks-Wilson Anna DeFazio Anna Fischer Arndt Hartmann Brenda Y Hernandez Bryan M McCauley Chloe Karpinskyj Christiani B de Sousa Claus Høgdall Daniel G Tiezzi Esther Herpel Florin Andrei Taran Francesmary Modugno Gary Keeney Gregg Nelson Helen Steed Honglin Song Hugh Luk Javier Benitez Jennifer Alsop Jennifer M Koziak Jenny Lester Joseph H Rothstein Jurandyr M de Andrade Lene Lundvall Luis Paz-Ares Luis Robles-Díaz Lynne R Wilkens Maria J Garcia Maria P Intermaggio Marie-Lyne Alcaraz Mary A Brett Matthias W Beckmann Mercedes Jimenez-Linan Michael Anglesio Michael E Carney Michael Schneider Nadia Traficante Nadja Pejovic Naveena Singh Nhu Le Peter Sinn Prafull Ghatage Ramona Erber Robert Edwards Robert Vierkant Roberta B Ness Samuel Leung Sandra Orsulic Sara Y Brucker Scott H Kaufmann Sian Fereday Simon Gayther Stacey J Winham Stefan Kommoss Tanja Pejovic Teri A Longacre Valerie McGuire Valerie Rhenius Weiva Sieh Yurii B Shvetsov Alice S Whittemore Annette Staebler Beth Y Karlan Cristina Rodriguez-Antona David D Bowtell Ellen L Goode Estrid Høgdall Francisco J Candido Dos Reis Jacek Gronwald Jenny Chang-Claude Kirsten B Moysich Linda E Kelemen Linda S Cook Marc T Goodman Peter A Fasching Robin Crawford Suha Deen Usha Menon David G Huntsman Martin Köbel Susan J Ramus Paul D P Pharoah James D Brenton

Br J Cancer 2020 Sep 18;123(5):793-802. Epub 2020 Jun 18.

Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, England.

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http://dx.doi.org/10.1038/s41416-020-0900-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463007PMC
September 2020

Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).

Authors:
Aline Talhouk Joshy George Chen Wang Timothy Budden Tuan Zea Tan Derek S Chiu Stefan Kommoss Huei San Leong Stephanie Chen Maria P Intermaggio Blake Gilks Tayyebeh M Nazeran Mila Volchek Wafaa Elatre Rex C Bentley Janine Senz Amy Lum Veronica Chow Hanwei Sudderuddin Robertson Mackenzie Samuel C Y Leong Geyi Liu Dustin Johnson Billy Chen Aocs Group Jennifer Alsop Susana N Banerjee Sabine Behrens Clara Bodelon Alison H Brand Louise Brinton Michael E Carney Yoke-Eng Chiew Kara L Cushing-Haugen Cezary Cybulski Darren Ennis Sian Fereday Renée T Fortner Jesús García-Donas Aleksandra Gentry-Maharaj Rosalind Glasspool Teodora Goranova Casey S Greene Paul Haluska Holly R Harris Joy Hendley Brenda Y Hernandez Esther Herpel Mercedes Jimenez-Linan Chloe Karpinskyj Scott H Kaufmann Gary L Keeney Catherine J Kennedy Martin Köbel Jennifer M Koziak Melissa C Larson Jenny Lester Liz-Anne Lewsley Jolanta Lissowska Jan Lubiński Hugh Luk Geoff Macintyre Sven Mahner Iain A McNeish Janusz Menkiszak Nikilyn Nevins Ana Osorio Oleg Oszurek José Palacios Samantha Hinsley Celeste L Pearce Malcolm C Pike Anna M Piskorz Isabelle Ray-Coquard Valerie Rhenius Cristina Rodriguez-Antona Raghwa Sharma Mark E Sherman Dilrini De Silva Naveena Singh Peter Sinn Dennis Slamon Honglin Song Helen Steed Euan A Stronach Pamela J Thompson Aleksandra Tołoczko Britton Trabert Nadia Traficante Chiu-Chen Tseng Martin Widschwendter Lynne R Wilkens Stacey J Winham Boris Winterhoff Alicia Beeghly-Fadiel Javier Benitez Andrew Berchuck James D Brenton Robert Brown Jenny Chang-Claude Georgia Chenevix-Trench Anna deFazio Peter A Fasching María J García Simon A Gayther Marc T Goodman Jacek Gronwald Michelle J Henderson Beth Y Karlan Linda E Kelemen Usha Menon Sandra Orsulic Paul D P Pharoah Nicolas Wentzensen Anna H Wu Joellen M Schildkraut Mary Anne Rossing Gottfried E Konecny David G Huntsman Ruby Yun-Ju Huang Ellen L Goode Susan J Ramus Jennifer A Doherty David D Bowtell Michael S Anglesio

Clin Cancer Res 2020 Jun 17. Epub 2020 Jun 17.

British Columbia's Gynecological Cancer Research Program (OVCARE), BC Cancer, Vancouver General Hospital, and University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-0103DOI Listing
June 2020

Improving response to progestin treatment of low-grade endometrial cancer.

Int J Gynecol Cancer 2020 May 6. Epub 2020 May 6.

Queensland Centre for Gynaecological Cancer Research, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1136/ijgc-2020-001309DOI Listing
May 2020

Examining indicators of early menopause following opportunistic salpingectomy: a cohort study from British Columbia, Canada.

Am J Obstet Gynecol 2020 08 15;223(2):221.e1-221.e11. Epub 2020 Feb 15.

Department of Gynaecology and Obstetrics, Division of Gynaecologic Oncology, University of British Columbia, Vancouver BC, Canada.

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http://dx.doi.org/10.1016/j.ajog.2020.02.005DOI Listing
August 2020

SWI/SNF Complex Mutations in Gynecologic Cancers: Molecular Mechanisms and Models.

Annu Rev Pathol 2020 01;15:467-492

Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia V5Z 1L3, Canada; email:

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http://dx.doi.org/10.1146/annurev-pathmechdis-012418-012917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986318PMC
January 2020

Histotype-specific analysis of acid ceramidase expression in ovarian cancer.

Virchows Arch 2020 Jun 2;476(6):855-862. Epub 2020 Jan 2.

Gynecology and Obstetrics, University Hospital Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1007/s00428-019-02728-0DOI Listing
June 2020

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 Sep 23;10(1):4386. Epub 2019 Sep 23.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-019-12095-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757065PMC
September 2019

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases.

Mod Pathol 2019 12 25;32(12):1834-1846. Epub 2019 Jun 25.

Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.

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http://dx.doi.org/10.1038/s41379-019-0302-0DOI Listing
December 2019

Expression of L1 retrotransposon open reading frame protein 1 in gynecologic cancers.

Hum Pathol 2019 10 18;92:39-47. Epub 2019 Jun 18.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V5Z 1L3, Canada; Department of Molecular Oncology, BC Cancer Agency, Vancouver, BC V5Z 4E6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2019.06.001DOI Listing
October 2019

Use of Immunohistochemical Markers (HNF-1β, Napsin A, ER, CTH, and ASS1) to Distinguish Endometrial Clear Cell Carcinoma From Its Morphologic Mimics Including Arias-Stella Reaction.

Int J Gynecol Pathol 2020 Jul;39(4):344-353

Department of Pathology and Laboratory Medicine, University of British Columbia (J.X.J., B.T.-C, B.G., D.G.H., L.N.H.) Department of Molecular Oncology, British Columbia Cancer Research Centre (D.R.C.) Genetic Pathology Evaluation Centre (S.L., A.S.C., C.C.) Department of Pathology, Vancouver General Hospital (B.G., L.N.H.), Vancouver, British Columbia, Canada.

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http://Insights.ovid.com/crossref?an=00004347-900000000-9910
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http://dx.doi.org/10.1097/PGP.0000000000000609DOI Listing
July 2020

Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk.

Authors:
Yaohua Yang Lang Wu Xiang Shu Yingchang Lu Xiao-Ou Shu Qiuyin Cai Alicia Beeghly-Fadiel Bingshan Li Fei Ye Andrew Berchuck Hoda Anton-Culver Susana Banerjee Javier Benitez Line Bjørge James D Brenton Ralf Butzow Ian G Campbell Jenny Chang-Claude Kexin Chen Linda S Cook Daniel W Cramer Anna deFazio Joe Dennis Jennifer A Doherty Thilo Dörk Diana M Eccles Digna Velez Edwards Peter A Fasching Renée T Fortner Simon A Gayther Graham G Giles Rosalind M Glasspool Ellen L Goode Marc T Goodman Jacek Gronwald Holly R Harris Florian Heitz Michelle A Hildebrandt Estrid Høgdall Claus K Høgdall David G Huntsman Siddhartha P Kar Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne K Kjaer Anita Koushik Diether Lambrechts Nhu D Le Douglas A Levine Leon F Massuger Keitaro Matsuo Taymaa May Iain A McNeish Usha Menon Francesmary Modugno Alvaro N Monteiro Patricia G Moorman Kirsten B Moysich Roberta B Ness Heli Nevanlinna Håkan Olsson N Charlotte Onland-Moret Sue K Park James Paul Celeste L Pearce Tanja Pejovic Catherine M Phelan Malcolm C Pike Susan J Ramus Elio Riboli Cristina Rodriguez-Antona Isabelle Romieu Dale P Sandler Joellen M Schildkraut Veronica W Setiawan Kang Shan Nadeem Siddiqui Weiva Sieh Meir J Stampfer Rebecca Sutphen Anthony J Swerdlow Lukasz M Szafron Soo Hwang Teo Shelley S Tworoger Jonathan P Tyrer Penelope M Webb Nicolas Wentzensen Emily White Walter C Willett Alicja Wolk Yin Ling Woo Anna H Wu Li Yan Drakoulis Yannoukakos Georgia Chenevix-Trench Thomas A Sellers Paul D P Pharoah Wei Zheng Jirong Long

Cancer Res 2019 02 17;79(3):505-517. Epub 2018 Dec 17.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-18-2726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359948PMC
February 2019

Histotype classification of ovarian carcinoma: A comparison of approaches.

Gynecol Oncol 2018 10 16;151(1):53-60. Epub 2018 Aug 16.

Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1016/j.ygyno.2018.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292681PMC
October 2018

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study.

Authors:
Peter F Rambau Robert A Vierkant Maria P Intermaggio Linda E Kelemen Marc T Goodman Esther Herpel Paul D Pharoah Stefan Kommoss Mercedes Jimenez-Linan Beth Y Karlan Aleksandra Gentry-Maharaj Usha Menon Susanna Hernando Polo Francisco J Candido Dos Reis Jennifer Anne Doherty Simon A Gayther Raghwa Sharma Melissa C Larson Paul R Harnett Emma Hatfield Jurandyr M de Andrade Gregg S Nelson Helen Steed Joellen M Schildkraut Micheal E Carney Estrid Høgdall Alice S Whittemore Martin Widschwendter Catherine J Kennedy Frances Wang Qin Wang Chen Wang Sebastian M Armasu Frances Daley Penny Coulson Micheal E Jones Micheal S Anglesio Christine Chow Anna de Fazio Montserrat García-Closas Sara Y Brucker Cezary Cybulski Holly R Harris Andreas D Hartkopf Tomasz Huzarski Allan Jensen Jan Lubiński Oleg Oszurek Javier Benitez Fady Mina Annette Staebler Florin Andrei Taran Jana Pasternak Aline Talhouk Mary Anne Rossing Joy Hendley Robert P Edwards Sian Fereday Francesmary Modugno Roberta B Ness Weiva Sieh Mona A El-Bahrawy Stacey J Winham Jenny Lester Susanne K Kjaer Jacek Gronwald Peter Sinn Peter A Fasching Jenny Chang-Claude Kirsten B Moysich David D Bowtell Brenda Y Hernandez Hugh Luk Sabine Behrens Mitul Shah Audrey Jung Prafull Ghatage Jennifer Alsop Kathryn Alsop Jesús García-Donas Pamela J Thompson Anthony J Swerdlow Chloe Karpinskyj Alicia Cazorla-Jiménez María J García Susha Deen Lynne R Wilkens José Palacios Andrew Berchuck Jennifer M Koziak James D Brenton Linda S Cook Ellen L Goode David G Huntsman Susan J Ramus Martin Köbel

J Pathol Clin Res 2018 10 21;4(4):250-261. Epub 2018 Sep 21.

Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.

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http://dx.doi.org/10.1002/cjp2.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174617PMC
October 2018

Tubo-Ovarian Transitional Cell Carcinoma and High-grade Serous Carcinoma Show Subtly Different Immunohistochemistry Profiles.

Int J Gynecol Pathol 2019 Nov;38(6):552-561

British Columbia Cancer Agency (J.M., A.N.K., A.T., D.C., D.G.H.) Department of Pathology, University of British Columbia (A.N.K., B.T.-C., C.C., A.C., C.B.G., D.G.H.), Vancouver, British Columbia, Canada Memorial Sloan Kettering Cancer Center, New York, New York (R.S.) Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands (S.H.) Department of Women's Health, Tübingen University Hospital, Tübingen (S.K.) Department of Gynecologic Oncology, Kliniken Essen Mitte, Essen (A.D.B.) Gynecologic Oncology Center, Kiel (J.P.) Institute of Pathology, Friedrichshafen (F.K.), Germany.

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http://dx.doi.org/10.1097/PGP.0000000000000538DOI Listing
November 2019

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

Authors:
Yingchang Lu Alicia Beeghly-Fadiel Lang Wu Xingyi Guo Bingshan Li Joellen M Schildkraut Hae Kyung Im Yian A Chen Jennifer B Permuth Brett M Reid Jamie K Teer Kirsten B Moysich Irene L Andrulis Hoda Anton-Culver Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Javier Benitez Line Bjorge James Brenton Ralf Butzow Trinidad Caldes Maria A Caligo Ian Campbell Jenny Chang-Claude Kathleen B M Claes Fergus J Couch Daniel W Cramer Mary B Daly Anna deFazio Joe Dennis Orland Diez Susan M Domchek Thilo Dörk Douglas F Easton Diana M Eccles Peter A Fasching Renée T Fortner George Fountzilas Eitan Friedman Patricia A Ganz Judy Garber Graham G Giles Andrew K Godwin David E Goldgar Marc T Goodman Mark H Greene Jacek Gronwald Ute Hamann Florian Heitz Michelle A T Hildebrandt Claus K Høgdall Antoinette Hollestelle Peter J Hulick David G Huntsman Evgeny N Imyanitov Claudine Isaacs Anna Jakubowska Paul James Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne K Kjaer Ava Kwong Nhu D Le Goska Leslie Fabienne Lesueur Douglas A Levine Amalia Mattiello Taymaa May Lesley McGuffog Iain A McNeish Melissa A Merritt Francesmary Modugno Marco Montagna Susan L Neuhausen Heli Nevanlinna Finn C Nielsen Liene Nikitina-Zake Robert L Nussbaum Kenneth Offit Edith Olah Olufunmilayo I Olopade Sara H Olson Håkan Olsson Ana Osorio Sue K Park Michael T Parsons Petra H M Peeters Tanja Pejovic Paolo Peterlongo Catherine M Phelan Miquel Angel Pujana Susan J Ramus Gad Rennert Harvey Risch Gustavo C Rodriguez Cristina Rodríguez-Antona Isabelle Romieu Matti A Rookus Mary Anne Rossing Iwona K Rzepecka Dale P Sandler Rita K Schmutzler Veronica W Setiawan Priyanka Sharma Weiva Sieh Jacques Simard Christian F Singer Honglin Song Melissa C Southey Amanda B Spurdle Rebecca Sutphen Anthony J Swerdlow Manuel R Teixeira Soo H Teo Mads Thomassen Marc Tischkowitz Amanda E Toland Antonia Trichopoulou Nadine Tung Shelley S Tworoger Elizabeth J van Rensburg Adriaan Vanderstichele Ana Vega Digna Velez Edwards Penelope M Webb Jeffrey N Weitzel Nicolas Wentzensen Emily White Alicja Wolk Anna H Wu Drakoulis Yannoukakos Kristin K Zorn Simon A Gayther Antonis C Antoniou Andrew Berchuck Ellen L Goode Georgia Chenevix-Trench Thomas A Sellers Paul D P Pharoah Wei Zheng Jirong Long

Cancer Res 2018 09 27;78(18):5419-5430. Epub 2018 Jul 27.

Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139053PMC
September 2018

Distinct developmental trajectories of endometriotic epithelium and stroma: implications for the origins of endometriosis.

J Pathol 2018 Nov 1;246(3):257-260. Epub 2018 Oct 1.

Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/path.5136DOI Listing
November 2018

Extending the safety evidence for opportunistic salpingectomy in prevention of ovarian cancer: a cohort study from British Columbia, Canada.

Am J Obstet Gynecol 2018 08 28;219(2):172.e1-172.e8. Epub 2018 May 28.

Department of Obstetrics and Gynaecology, Division of Gynaecologic Oncology, University of British Columbia, Vancouver BC, Canada.

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http://dx.doi.org/10.1016/j.ajog.2018.05.019DOI Listing
August 2018

Changing Clinical Practice: Evaluation of Implementing Recommendations for Opportunistic Salpingectomy in British Columbia and Ontario.

Int J Gynecol Cancer 2018 07;28(6):1101-1107

Division of Gynecologic Oncology, University of British Columbia, Vancouver General Hospital.

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http://dx.doi.org/10.1097/IGC.0000000000001288DOI Listing
July 2018

High Frequency of Ovarian Cyst Development in Vhl;Snf5 Mice.

Am J Pathol 2018 07 22;188(7):1510-1516. Epub 2018 Apr 22.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024179PMC
July 2018

DICER1 hot-spot mutations in ovarian gynandroblastoma.

Histopathology 2018 Aug 5;73(2):306-313. Epub 2018 Jun 5.

Institute of Pathology, Medizin Campus Bodensee, Friedrichshafen, Germany.

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http://dx.doi.org/10.1111/his.13630DOI Listing
August 2018

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer.

Mayo Clin Proc 2018 03;93(3):307-320

Department of Health Sciences Research, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2017.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870793PMC
March 2018

The molecular pathology of cancer: from pan-genomics to post-genomics.

J Pathol 2018 04;244(5):509-511

Department of Pathology and Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1002/path.5057DOI Listing
April 2018

Clear cell carcinomas of the ovary and kidney: clarity through genomics.

J Pathol 2018 04 23;244(5):550-564. Epub 2018 Feb 23.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/path.5037DOI Listing
April 2018

APELA promotes tumour growth and cell migration in ovarian cancer in a p53-dependent manner.

Gynecol Oncol 2017 12 24;147(3):663-671. Epub 2017 Oct 24.

Terry Fox Laboratory, BC Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada; Cell and Developmental Biology Program, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2017.10.016DOI Listing
December 2017

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

Authors:
Ellen L Goode Matthew S Block Kimberly R Kalli Robert A Vierkant Wenqian Chen Zachary C Fogarty Aleksandra Gentry-Maharaj Aleksandra Tołoczko Alexander Hein Aliecia L Bouligny Allan Jensen Ana Osorio Andreas Hartkopf Andy Ryan Anita Chudecka-Głaz Anthony M Magliocco Arndt Hartmann Audrey Y Jung Bo Gao Brenda Y Hernandez Brooke L Fridley Bryan M McCauley Catherine J Kennedy Chen Wang Chloe Karpinskyj Christiani B de Sousa Daniel G Tiezzi David L Wachter Esther Herpel Florin Andrei Taran Francesmary Modugno Gregg Nelson Jan Lubiński Janusz Menkiszak Jennifer Alsop Jenny Lester Jesús García-Donas Jill Nation Jillian Hung José Palacios Joseph H Rothstein Joseph L Kelley Jurandyr M de Andrade Luis Robles-Díaz Maria P Intermaggio Martin Widschwendter Matthias W Beckmann Matthias Ruebner Mercedes Jimenez-Linan Naveena Singh Oleg Oszurek Paul R Harnett Peter F Rambau Peter Sinn Philipp Wagner Prafull Ghatage Raghwa Sharma Robert P Edwards Roberta B Ness Sandra Orsulic Sara Y Brucker Sharon E Johnatty Teri A Longacre Eilber Ursula Valerie McGuire Weiva Sieh Yanina Natanzon Zheng Li Alice S Whittemore deFazio Anna Annette Staebler Beth Y Karlan Blake Gilks David D Bowtell Estrid Høgdall Francisco J Candido dos Reis Helen Steed Ian G Campbell Jacek Gronwald Javier Benítez Jennifer M Koziak Jenny Chang-Claude Kirsten B Moysich Linda E Kelemen Linda S Cook Marc T Goodman María José García Peter A Fasching Stefan Kommoss Suha Deen Susanne K Kjaer Usha Menon James D Brenton Paul DP Pharoah Georgia Chenevix-Trench David G Huntsman Stacey J Winham Martin Köbel Susan J Ramus

JAMA Oncol 2017 12;3(12):e173290

School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia

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http://dx.doi.org/10.1001/jamaoncol.2017.3290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744673PMC
December 2017

LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers.

Gynecol Oncol 2017 12 9;147(3):642-647. Epub 2017 Oct 9.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Molecular Oncology, BC Cancer Agency, Vancouver, BC, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258173135
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http://dx.doi.org/10.1016/j.ygyno.2017.09.032DOI Listing
December 2017

Cancer-Associated Mutations in Endometriosis without Cancer.

N Engl J Med 2017 05;376(19):1835-1848

From the Departments of Obstetrics and Gynaecology (M.S.A., C.A., C.W., P.J.Y., D.G.H.) and Pathology and Laboratory Medicine (M.S.A., T.M.N., J. Senz, B.T.-C., C.B.G., D.G.H.), University of British Columbia, the Department of Anatomical Pathology, Vancouver General Hospital (T.M.N., H.M.H., J.H., V.L., B.T.-C., A.W., C.B.G., D.G.H.), the Department of Molecular Oncology, British Columbia Cancer Agency (H.M.H., A.L., V.L., N.B., D.G.H.), and the BC Women's Centre for Pelvic Pain and Endometriosis, BC Women's Hospital and Health Centre (F.W., N.O., C.A., C.W., P.J.Y.) - all in Vancouver, BC, Canada; the Department of Oncology (N.P., C.T., K.W.K., L.D., T.-L.W., B.V., I.-M.S.) and Ludwig Center (N.P., Y.W., J.D.C., M.Z., M.P., W.M., A.M., K.W.K., L.D., B.V.), Sidney Kimmel Comprehensive Cancer Center, the Departments of Pathology (N.P., A.A., M.N., L.D.W., T.-L.W., B.V., I.-M.S.) and Gynecology and Obstetrics (J. Segars, I.-M.S.), Johns Hopkins Medical Institutions, Personal Genome Diagnostics (S.J.), and Johns Hopkins University Howard Hughes Medical Institute (B.V.) - all in Baltimore; the Department of Pathology, Seirei Mikatahara Hospital (A.A., H.O.), and the Department of Tumor Pathology, Hamamatsu University School of Medicine (A.A.), Hamamatsu, and the Department of Molecular Pathology, Hiroshima University School of Medicine, Hiroshima (A.A.) - all in Japan; the Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands (M.N.); the Departments of Obstetrics and Gynecology (T.S.) and Pathology (R.A., A.H.), Lenox Hill Hospital-Northwell Health (Hofstra University), New York; and the Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Tao-Yuan City, Taiwan (R.-C.W.).

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http://dx.doi.org/10.1056/NEJMoa1614814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555376PMC
May 2017

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

J Pathol 2017 07 2;242(3):371-383. Epub 2017 Jun 2.

Department of Pathology and Laboratory Medicine, University of British Columbia and Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada.

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http://doi.wiley.com/10.1002/path.4912
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http://dx.doi.org/10.1002/path.4912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857704PMC
July 2017

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Authors:
Catherine M Phelan Karoline B Kuchenbaecker Jonathan P Tyrer Siddhartha P Kar Kate Lawrenson Stacey J Winham Joe Dennis Ailith Pirie Marjorie J Riggan Ganna Chornokur Madalene A Earp Paulo C Lyra Janet M Lee Simon Coetzee Jonathan Beesley Lesley McGuffog Penny Soucy Ed Dicks Andrew Lee Daniel Barrowdale Julie Lecarpentier Goska Leslie Cora M Aalfs Katja K H Aben Marcia Adams Julian Adlard Irene L Andrulis Hoda Anton-Culver Natalia Antonenkova Gerasimos Aravantinos Norbert Arnold Banu K Arun Brita Arver Jacopo Azzollini Judith Balmaña Susana N Banerjee Laure Barjhoux Rosa B Barkardottir Yukie Bean Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Marina Bermisheva Marcus Q Bernardini Michael J Birrer Line Bjorge Amanda Black Kenneth Blankstein Marinus J Blok Clara Bodelon Natalia Bogdanova Anders Bojesen Bernardo Bonanni Åke Borg Angela R Bradbury James D Brenton Carole Brewer Louise Brinton Per Broberg Angela Brooks-Wilson Fiona Bruinsma Joan Brunet Bruno Buecher Ralf Butzow Saundra S Buys Trinidad Caldes Maria A Caligo Ian Campbell Rikki Cannioto Michael E Carney Terence Cescon Salina B Chan Jenny Chang-Claude Stephen Chanock Xiao Qing Chen Yoke-Eng Chiew Jocelyne Chiquette Wendy K Chung Kathleen B M Claes Thomas Conner Linda S Cook Jackie Cook Daniel W Cramer Julie M Cunningham Aimee A D'Aloisio Mary B Daly Francesca Damiola Sakaeva Dina Damirovna Agnieszka Dansonka-Mieszkowska Fanny Dao Rosemarie Davidson Anna DeFazio Capucine Delnatte Kimberly F Doheny Orland Diez Yuan Chun Ding Jennifer Anne Doherty Susan M Domchek Cecilia M Dorfling Thilo Dörk Laure Dossus Mercedes Duran Matthias Dürst Bernd Dworniczak Diana Eccles Todd Edwards Ros Eeles Ursula Eilber Bent Ejlertsen Arif B Ekici Steve Ellis Mingajeva Elvira Kevin H Eng Christoph Engel D Gareth Evans Peter A Fasching Sarah Ferguson Sandra Fert Ferrer James M Flanagan Zachary C Fogarty Renée T Fortner Florentia Fostira William D Foulkes George Fountzilas Brooke L Fridley Tara M Friebel Eitan Friedman Debra Frost Patricia A Ganz Judy Garber María J García Vanesa Garcia-Barberan Andrea Gehrig Aleksandra Gentry-Maharaj Anne-Marie Gerdes Graham G Giles Rosalind Glasspool Gord Glendon Andrew K Godwin David E Goldgar Teodora Goranova Martin Gore Mark H Greene Jacek Gronwald Stephen Gruber Eric Hahnen Christopher A Haiman Niclas Håkansson Ute Hamann Thomas V O Hansen Patricia A Harrington Holly R Harris Jan Hauke Alexander Hein Alex Henderson Michelle A T Hildebrandt Peter Hillemanns Shirley Hodgson Claus K Høgdall Estrid Høgdall Frans B L Hogervorst Helene Holland Maartje J Hooning Karen Hosking Ruea-Yea Huang Peter J Hulick Jillian Hung David J Hunter David G Huntsman Tomasz Huzarski Evgeny N Imyanitov Claudine Isaacs Edwin S Iversen Louise Izatt Angel Izquierdo Anna Jakubowska Paul James Ramunas Janavicius Mats Jernetz Allan Jensen Uffe Birk Jensen Esther M John Sharon Johnatty Michael E Jones Päivi Kannisto Beth Y Karlan Anthony Karnezis Karin Kast Catherine J Kennedy Elza Khusnutdinova Lambertus A Kiemeney Johanna I Kiiski Sung-Won Kim Susanne K Kjaer Martin Köbel Reidun K Kopperud Torben A Kruse Jolanta Kupryjanczyk Ava Kwong Yael Laitman Diether Lambrechts Nerea Larrañaga Melissa C Larson Conxi Lazaro Nhu D Le Loic Le Marchand Jong Won Lee Shashikant B Lele Arto Leminen Dominique Leroux Jenny Lester Fabienne Lesueur Douglas A Levine Dong Liang Clemens Liebrich Jenna Lilyquist Loren Lipworth Jolanta Lissowska Karen H Lu Jan Lubinński Craig Luccarini Lene Lundvall Phuong L Mai Gustavo Mendoza-Fandiño Siranoush Manoukian Leon F A G Massuger Taymaa May Sylvie Mazoyer Jessica N McAlpine Valerie McGuire John R McLaughlin Iain McNeish Hanne Meijers-Heijboer Alfons Meindl Usha Menon Arjen R Mensenkamp Melissa A Merritt Roger L Milne Gillian Mitchell Francesmary Modugno Joanna Moes-Sosnowska Melissa Moffitt Marco Montagna Kirsten B Moysich Anna Marie Mulligan Jacob Musinsky Katherine L Nathanson Lotte Nedergaard Roberta B Ness Susan L Neuhausen Heli Nevanlinna Dieter Niederacher Robert L Nussbaum Kunle Odunsi Edith Olah Olufunmilayo I Olopade Håkan Olsson Curtis Olswold David M O'Malley Kai-Ren Ong N Charlotte Onland-Moret Nicholas Orr Sandra Orsulic Ana Osorio Domenico Palli Laura Papi Tjoung-Won Park-Simon James Paul Celeste L Pearce Inge Søkilde Pedersen Petra H M Peeters Bernard Peissel Ana Peixoto Tanja Pejovic Liisa M Pelttari Jennifer B Permuth Paolo Peterlongo Lidia Pezzani Georg Pfeiler Kelly-Anne Phillips Marion Piedmonte Malcolm C Pike Anna M Piskorz Samantha R Poblete Timea Pocza Elizabeth M Poole Bruce Poppe Mary E Porteous Fabienne Prieur Darya Prokofyeva Elizabeth Pugh Miquel Angel Pujana Pascal Pujol Paolo Radice Johanna Rantala Christine Rappaport-Fuerhauser Gad Rennert Kerstin Rhiem Patricia Rice Andrea Richardson Mark Robson Gustavo C Rodriguez Cristina Rodríguez-Antona Jane Romm Matti A Rookus Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Helga B Salvesen Dale P Sandler Minouk J Schoemaker Leigha Senter V Wendy Setiawan Gianluca Severi Priyanka Sharma Tameka Shelford Nadeem Siddiqui Lucy E Side Weiva Sieh Christian F Singer Hagay Sobol Honglin Song Melissa C Southey Amanda B Spurdle Zsofia Stadler Doris Steinemann Dominique Stoppa-Lyonnet Lara E Sucheston-Campbell Grzegorz Sukiennicki Rebecca Sutphen Christian Sutter Anthony J Swerdlow Csilla I Szabo Lukasz Szafron Yen Y Tan Jack A Taylor Muy-Kheng Tea Manuel R Teixeira Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Liv Cecilie Vestrheim Thomsen Darcy L Thull Laima Tihomirova Anna V Tinker Marc Tischkowitz Silvia Tognazzo Amanda Ewart Toland Alicia Tone Britton Trabert Ruth C Travis Antonia Trichopoulou Nadine Tung Shelley S Tworoger Anne M van Altena David Van Den Berg Annemarie H van der Hout Rob B van der Luijt Mattias Van Heetvelde Els Van Nieuwenhuysen Elizabeth J van Rensburg Adriaan Vanderstichele Raymonda Varon-Mateeva Ana Vega Digna Velez Edwards Ignace Vergote Robert A Vierkant Joseph Vijai Athanassios Vratimos Lisa Walker Christine Walsh Dorothea Wand Shan Wang-Gohrke Barbara Wappenschmidt Penelope M Webb Clarice R Weinberg Jeffrey N Weitzel Nicolas Wentzensen Alice S Whittemore Juul T Wijnen Lynne R Wilkens Alicja Wolk Michelle Woo Xifeng Wu Anna H Wu Hannah Yang Drakoulis Yannoukakos Argyrios Ziogas Kristin K Zorn Steven A Narod Douglas F Easton Christopher I Amos Joellen M Schildkraut Susan J Ramus Laura Ottini Marc T Goodman Sue K Park Linda E Kelemen Harvey A Risch Mads Thomassen Kenneth Offit Jacques Simard Rita Katharina Schmutzler Dennis Hazelett Alvaro N Monteiro Fergus J Couch Andrew Berchuck Georgia Chenevix-Trench Ellen L Goode Thomas A Sellers Simon A Gayther Antonis C Antoniou Paul D P Pharoah

Nat Genet 2017 May 27;49(5):680-691. Epub 2017 Mar 27.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612337PMC
May 2017

Pathogenesis and treatment of adult-type granulosa cell tumor of the ovary.

Ann Med 2017 08 6;49(5):435-447. Epub 2017 Mar 6.

b Children's Hospital , University of Helsinki and Helsinki University Hospital , Helsinki , Finland.

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http://dx.doi.org/10.1080/07853890.2017.1294760DOI Listing
August 2017

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci.

Br J Cancer 2017 Feb 19;116(4):524-535. Epub 2017 Jan 19.

Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1038/bjc.2016.426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318969PMC
February 2017

Interobserver Agreement in Endometrial Carcinoma Histotype Diagnosis Varies Depending on The Cancer Genome Atlas (TCGA)-based Molecular Subgroup.

Am J Surg Pathol 2017 Feb;41(2):245-252

*Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY †Department of Pathology and Laboratory Medicine, and Genetic Pathology Evaluation Center, Vancouver General Hospital, University of British Columbia **Department of Gynecology and Obstetrics, University of British Columbia, Vancouver, BC ‡Department of Pathology, Saskatoon City Hospital, Saskatoon, SK §Department of Pathology, Laval University, Quebec City #Department of Human Genetics, McGill University, Research Institute of the McGill University Health Network, Montreal, QC ∥Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital, University of Alberta, Edmonton ¶Department of Pathology and Laboratory Medicine, Calgary Laboratory Services, University of Calgary, Calgary, AB, Canada.

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https://insights.ovid.com/crossref?an=00000478-201702000-000
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http://dx.doi.org/10.1097/PAS.0000000000000764DOI Listing
February 2017

Confirmation of ProMisE: A simple, genomics-based clinical classifier for endometrial cancer.

Cancer 2017 03 6;123(5):802-813. Epub 2017 Jan 6.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/cncr.30496DOI Listing
March 2017

The disparate origins of ovarian cancers: pathogenesis and prevention strategies.

Nat Rev Cancer 2017 01 25;17(1):65-74. Epub 2016 Nov 25.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V5Z 1M9, Canada.

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http://dx.doi.org/10.1038/nrc.2016.113DOI Listing
January 2017

Differences in MEK inhibitor efficacy in molecularly characterized low-grade serous ovarian cancer cell lines.

Am J Cancer Res 2016 1;6(10):2235-2251. Epub 2016 Oct 1.

Department of Obstetrics & Gynaecology, University of British ColumbiaVancouver, British Columbia, Canada; Department of Surgical Oncology, BC Cancer AgencyVancouver, British Columbia, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088288PMC
October 2016

FOXL2 402C>G Mutation Can Be Identified in the Circulating Tumor DNA of Patients with Adult-Type Granulosa Cell Tumor.

J Mol Diagn 2017 01 1;19(1):126-136. Epub 2016 Nov 1.

Department of Pathology and Laboratory Medicine, University of British Columbia, and the Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.08.005DOI Listing
January 2017

Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research.

Sci Rep 2016 10 7;6:34949. Epub 2016 Oct 7.

Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/srep34949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054533PMC
October 2016

Frequent NFIB-associated Gene Rearrangement in Adenoid Cystic Carcinoma of the Vulva.

Int J Gynecol Pathol 2017 May;36(3):289-293

Department of Pathology (D.X., B.M.R.), The Johns Hopkins Medical Institutions, Baltimore, MDDepartment of Pathology and Laboratory Medicine (S.B., N.M., J.H., D.G.H., C.B.G., H.H.), University of British Columbia, Vancouver, BC, CanadaCellNetix Pathology (C.I.), Seattle, WA.

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http://dx.doi.org/10.1097/PGP.0000000000000324DOI Listing
May 2017

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

Mod Pathol 2016 12 26;29(12):1586-1593. Epub 2016 Aug 26.

Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital and University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1038/modpathol.2016.156DOI Listing
December 2016

In-depth molecular profiling of the biphasic components of uterine carcinosarcomas.

J Pathol Clin Res 2015 Jul 9;1(3):173-85. Epub 2015 Apr 9.

Department of Laboratory Medicine and Pathology Royal Alexandra Hospital and University of Alberta Edmonton Canada.

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http://dx.doi.org/10.1002/cjp2.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939881PMC
July 2015

Molecular classification of endometrial carcinoma on diagnostic specimens is highly concordant with final hysterectomy: Earlier prognostic information to guide treatment.

Gynecol Oncol 2016 10 14;143(1):46-53. Epub 2016 Jul 14.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, 2775 Laurel St., 6th Floor, Vancouver, British Columbia V5Z 1M9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.07.090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521211PMC
October 2016

Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype.

J Natl Cancer Inst 2016 11 13;108(11). Epub 2016 Jun 13.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver General Hospital and BC Cancer Agency, Vancouver, Canada (MKM, HMH, AT, WY, NR, CBG, DGH); Biomedicum Helsinki, University of Helsinki, Helsinki, Finland (AF, LUK, SB, MA); Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland (AF, LUK, SB, MA); Centre of Gynaecologic Oncology Amsterdam (HSvM, MRB, GGK) and Department of Pathology (JBGH, GKJH, MJvdV, MCGB), Academic Medical Center, Amsterdam, the Netherlands; Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland (NA, MH); Department of Obstetrics and Gynaecology, Tübingen University Hospital, Department of Women's Health, Tübingen, Germany (KZ, SYB, BK, SK); Department of Pathology (RB) and Department of Clinical Chemistry and Hematology (MA), Helsinki University Hospital, University of Helsinki and HUSLAB, Helsinki, Finland; Institute of Pathology, Tübingen University Hospital, Tübingen, Germany (AS); Department of Pediatrics, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO (MH); Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada (DGH); Department of Human Genetics, Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada (MKM)

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http://dx.doi.org/10.1093/jnci/djw134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241905PMC
November 2016

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Am J Hum Genet 2016 05 14;98(5):830-842. Epub 2016 Apr 14.

Department of Genetics and Computational Biology, QIMR Berghofer, Herston, QLD 4029, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863475PMC
May 2016

BAF250a Expression in Atypical Endometriosis and Endometriosis-Associated Ovarian Cancer.

Int J Gynecol Cancer 2016 06;26(5):825-32

Departments of *Obstetrics and Gynecology, and †Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada; ‡Faculty of Medicine, Universiteit van Amsterdam, Amsterdam, the Netherlands; §Department of Pathology and Laboratory Medicine, BC Cancer Agency; ∥Genetic Pathology Evaluation Centre, University of British Columbia, Vancouver, British Columbia; ¶Division of Gynecologic Oncology, Princess Margaret Cancer Centre, Toronto, Ontario; and #Hereditary Cancer Program, BC Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/IGC.0000000000000698DOI Listing
June 2016

The influence of clinical and genetic factors on patient outcome in small cell carcinoma of the ovary, hypercalcemic type.

Gynecol Oncol 2016 06 19;141(3):454-460. Epub 2016 Mar 19.

Department of Human Genetics, McGill University, Montreal, QC, Canada; Lady Davis Institute and Segal Cancer Center, Jewish General Hospital, Montreal, QC, Canada; Department of Medical Genetics and Cancer Research Program, Research Institute, McGill University Health Centre, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876126PMC
June 2016

Rare cancers: a sea of opportunity.

Lancet Oncol 2016 Feb;17(2):e52-e61

Department of Molecular Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada; Department of Pathology and Laboratory Medicine and Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)00386-1DOI Listing
February 2016

Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality.

J Natl Cancer Inst 2016 Jun 1;108(6):djv428. Epub 2016 Feb 1.

Department of Pathology and Laboratory Medicine, (MSA, HMH, JS, HLC, ANK, BSS, MKM, CBG, SK, DGH) and Department of Obstetrics and Gynaecology (MSA, DGH), University of British Columbia, Vancouver, Canada; Department of Molecular Oncology, British Columbia Cancer Agency Cancer Research Centre, Vancouver, Canada (YKW, AB, RM, DSG, SPS); Department of Women's Health, University Hospital Tuebingen, Tuebingen, Germany (MM, FAT, DW, SB, SK); Division of Anatomic Pathology, Synlab MVZ, Institute of Pathology, Mannheim, Germany (FK); Division of Gynecologic Pathology, Institute of Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany (AS); Department of Anatomical Pathology, Vancouver General Hospital, Vancouver, Canada (CBG).

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http://dx.doi.org/10.1093/jnci/djv428DOI Listing
June 2016

Endometrial Carcinomas with POLE Exonuclease Domain Mutations Have a Favorable Prognosis.

Clin Cancer Res 2016 06 13;22(12):2865-73. Epub 2016 Jan 13.

Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://clincancerres.aacrjournals.org/content/early/2016/01/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-15-2233DOI Listing
June 2016

The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors.

Neoplasia 2015 Aug;17(8):650-60

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada; Department of Molecular Oncology, British Columbia Cancer Agency Cancer Research Centre, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2015.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674484PMC
August 2015

The genomic landscape of epithelioid sarcoma cell lines and tumours.

J Pathol 2016 Jan 19;238(1):63-73. Epub 2015 Oct 19.

Genetic Pathology Evaluation Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/path.4636DOI Listing
January 2016

Using Somatic Mutations to Guide Treatment Decisions: Context Matters.

JAMA Oncol 2015 Jun;1(3):275-6

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada2Department of Molecular Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada4Department of Obstetrics and Gynecol.

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http://dx.doi.org/10.1001/jamaoncol.2015.35DOI Listing
June 2015

Polymerase Epsilon Exonuclease Domain Mutations in Ovarian Endometrioid Carcinoma.

Int J Gynecol Cancer 2015 Sep;25(7):1187-93

*Department of Pathology and Laboratory Medicine, and Genetic Pathology Evaluation Center, Vancouver General Hospital; †University of British Columbia, Vancouver; ‡Department of Pathology and Laboratory Medicine, Calgary Laboratory Services; §University of Calgary, Calgary, Canada; ∥Department of Gynecology and Obstetrics, Tübingen University, Tübingen, Germany; ¶Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital; #University of Alberta; **Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada; ††Department of Public Health Sciences, Medical University of South Carolina; ‡‡Hollings Cancer Center, Charleston, SC; and §§Department of Gynecology and Obstetrics, University of British Columbia, Vancouver, Canada.

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http://pdfs.journals.lww.com/ijgc/2015/09000/Polymerase_Epsi
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IGC.0000000000000492DOI Listing
September 2015