David G Clark

David G Clark

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Down regulation of p-coumarate 3-hydroxylase in petunia uniquely alters the profile of emitted floral volatiles.

Sci Rep 2019 Jun 20;9(1):8852. Epub 2019 Jun 20.

Environmental Horticulture Department, Plant Innovation Center, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, 32611, USA.

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http://dx.doi.org/10.1038/s41598-019-45183-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586934PMC
June 2019

Down regulation of p-coumarate 3-hydroxylase in petunia uniquely alters the profile of emitted floral volatiles.

Sci Rep 2019 Jun 20;9(1):8852. Epub 2019 Jun 20.

Environmental Horticulture Department, Plant Innovation Center, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, 32611, USA.

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http://dx.doi.org/10.1038/s41598-019-45183-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586934PMC
June 2019

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease.

Neurobiol Aging 2017 01 3;49:216.e7-216.e13. Epub 2016 Oct 3.

Alzheimer's Disease Center, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA; McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154842PMC
January 2017

Identifying Breeding Priorities for Blueberry Flavor Using Biochemical, Sensory, and Genotype by Environment Analyses.

PLoS One 2015 17;10(9):e0138494. Epub 2015 Sep 17.

Plant Innovation Center, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, United States of America; Horticultural Sciences Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138494PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574478PMC
May 2016

Lilium floral fragrance: A biochemical and genetic resource for aroma and flavor.

Phytochemistry 2016 Feb 1;122:103-112. Epub 2015 Dec 1.

Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, FL 32611, USA; Environmental Horticulture Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611, USA; Plant Innovation Center, University of Florida, Gainesville, FL 32611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2015.11.010DOI Listing
February 2016

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

Authors:
Li-San Wang Adam C Naj Robert R Graham Paul K Crane Brian W Kunkle Carlos Cruchaga Josue D Gonzalez Murcia Lisa Cannon-Albright Clinton T Baldwin Henrik Zetterberg Kaj Blennow Walter A Kukull Kelley M Faber Nicole Schupf Maria C Norton JoAnn T Tschanz Ronald G Munger Christopher D Corcoran Ekaterina Rogaeva Chiao-Feng Lin Beth A Dombroski Laura B Cantwell Amanda Partch Otto Valladares Hakon Hakonarson Peter St George-Hyslop Robert C Green Alison M Goate Tatiana M Foroud Regina M Carney Eric B Larson Timothy W Behrens John S K Kauwe Jonathan L Haines Lindsay A Farrer Margaret A Pericak-Vance Richard Mayeux Gerard D Schellenberg Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Michael Barmada Lisa L Barnes Thomas G Beach James T Becker Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Steven L Carroll Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky F Yesim Demirci Malcolm Dick Dennis W Dickson Ranjan Duara Nilufer Ertekin-Taner Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass Neill R Graff-Radford John H Growdon Ronald L Hamilton Kara L Hamilton-Nelson Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun Gyungah Jun M Ilyas Kamboh Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Gei Li Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Constantine G Lyketsos Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee W Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Jill R Murrell John M Olichney Joseph E Parisi William Perry Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2015 Feb;72(2):209-16

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jamaneurol.2014.2157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324097PMC
February 2015

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

Authors:
Adam C Naj Gyungah Jun Christiane Reitz Brian W Kunkle William Perry Yo Son Park Gary W Beecham Ruchita A Rajbhandary Kara L Hamilton-Nelson Li-San Wang John S K Kauwe Matthew J Huentelman Amanda J Myers Thomas D Bird Bradley F Boeve Clinton T Baldwin Gail P Jarvik Paul K Crane Ekaterina Rogaeva M Michael Barmada F Yesim Demirci Carlos Cruchaga Patricia L Kramer Nilufer Ertekin-Taner John Hardy Neill R Graff-Radford Robert C Green Eric B Larson Peter H St George-Hyslop Joseph D Buxbaum Denis A Evans Julie A Schneider Kathryn L Lunetta M Ilyas Kamboh Andrew J Saykin Eric M Reiman Philip L De Jager David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Eden R Martin Jonathan L Haines Richard P Mayeux Lindsay A Farrer Gerard D Schellenberg Margaret A Pericak-Vance Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Lisa L Barnes Thomas G Beach James T Becker Duane Beekly Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Minerva M Carrasquillo Steven L Carroll Helena C Chui David G Clark Jason Corneveaux David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky Malcolm Dick Dennis W Dickson Ranjan Duara Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Chiao-Feng Lin Oscar L Lopez Constantine G Lyketsos Wendy J Mack Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Jill R Murrell John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Otto Valladares Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2014 Nov;71(11):1394-404

Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamaneurol.2014.1491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314944PMC
November 2014

Strawberry flavor: diverse chemical compositions, a seasonal influence, and effects on sensory perception.

PLoS One 2014 11;9(2):e88446. Epub 2014 Feb 11.

Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, Florida, United States of America ; Department of Environmental Horticulture, University of Florida, Gainesville, Florida, United States of America ; Plant Innovation Program, University of Florida, Gainesville, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088446PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921181PMC
October 2014

PhDAHP1 is required for floral volatile benzenoid/phenylpropanoid biosynthesis in Petunia × hybrida cv 'Mitchell Diploid'.

Phytochemistry 2014 Jul 6;103:22-31. Epub 2014 May 6.

Plant Innovation Program, Department of Environmental Horticulture, University of Florida, Gainesville, FL 32611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2014.04.004DOI Listing
July 2014

Basal ganglia volume in unmedicated patients with schizophrenia is associated with treatment response to antipsychotic medication.

Psychiatry Res 2014 Jan 22;221(1):6-12. Epub 2013 Oct 22.

Department of Psychiatry and Behavioral Neurobiology, The University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2013.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947916PMC
January 2014

Petunia flowers solve the defence/apparency dilemma of pollinator attraction by deploying complex floral blends.

Ecol Lett 2013 Mar 23;16(3):299-306. Epub 2012 Nov 23.

Department of Molecular Ecology, Max-Planck-Institute for Chemical Ecology, Hans-Knöll-Str. 8, DE-07745, Jena, Germany.

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http://doi.wiley.com/10.1111/ele.12038
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http://dx.doi.org/10.1111/ele.12038DOI Listing
March 2013

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://dx.doi.org/10.1212/WNL.0b013e3182605801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Authors:
Adam C Naj Gyungah Jun Gary W Beecham Li-San Wang Badri Narayan Vardarajan Jacqueline Buros Paul J Gallins Joseph D Buxbaum Gail P Jarvik Paul K Crane Eric B Larson Thomas D Bird Bradley F Boeve Neill R Graff-Radford Philip L De Jager Denis Evans Julie A Schneider Minerva M Carrasquillo Nilufer Ertekin-Taner Steven G Younkin Carlos Cruchaga John S K Kauwe Petra Nowotny Patricia Kramer John Hardy Matthew J Huentelman Amanda J Myers Michael M Barmada F Yesim Demirci Clinton T Baldwin Robert C Green Ekaterina Rogaeva Peter St George-Hyslop Steven E Arnold Robert Barber Thomas Beach Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Jeffrey L Cummings Charles DeCarli Steven T DeKosky Ramon Diaz-Arrastia Malcolm Dick Dennis W Dickson William G Ellis Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Nancy Johnson Jason Karlawish Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall James J Lah Allan I Levey Andrew P Lieberman Oscar L Lopez Wendy J Mack Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Joseph E Parisi Daniel P Perl Elaine Peskind Ronald C Petersen Wayne W Poon Joseph F Quinn Ruchita A Rajbhandary Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Roger N Rosenberg Mary Sano Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer Laura B Cantwell Beth A Dombroski Duane Beekly Kathryn L Lunetta Eden R Martin M Ilyas Kamboh Andrew J Saykin Eric M Reiman David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg

Nat Genet 2011 May 3;43(5):436-41. Epub 2011 Apr 3.

The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.

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http://dx.doi.org/10.1038/ng.801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090745PMC
May 2011

Unraveling the regulation of floral fragrance biosynthesis.

Plant Signal Behav 2011 Mar;6(3):378-81

Environmental Horticulture Department, University of Florida, Gainesville, FL, USA.

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https://www.tandfonline.com/doi/full/10.4161/psb.6.3.14339
Publisher Site
http://dx.doi.org/10.4161/psb.6.3.14339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142419PMC
March 2011

PhMYB4 fine-tunes the floral volatile signature of Petunia x hybrida through PhC4H.

J Exp Bot 2011 Jan 10;62(3):1133-43. Epub 2010 Nov 10.

Department of Environmental Horticulture, University of Florida, 1523 Fifield Hall, Gainesville, Florida 32611, USA.

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http://dx.doi.org/10.1093/jxb/erq342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022401PMC
January 2011

Brain metabolic correlates of decision making in amnestic mild cognitive impairment.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 2010 6;17(4):492-504. Epub 2010 Apr 6.

Departments of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1080/13825581003646135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133695PMC
October 2010

Carotenoid content impacts flavor acceptability in tomato (Solanum lycopersicum).

J Sci Food Agric 2010 Oct;90(13):2233-40

Horticultural Sciences, University of Florida, Gainesville, Florida 32611, USA.

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http://ucanr.edu/datastoreFiles/608-183.pdf
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http://doi.wiley.com/10.1002/jsfa.4076
Publisher Site
http://dx.doi.org/10.1002/jsfa.4076DOI Listing
October 2010

Petunia floral volatile benzenoid/phenylpropanoid genes are regulated in a similar manner.

Phytochemistry 2010 Feb 2;71(2-3):158-67. Epub 2009 Nov 2.

Department of Environmental Horticulture, University of Florida, P.O. Box 110670, Gainesville, FL 32611, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S003194220900427
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http://dx.doi.org/10.1016/j.phytochem.2009.09.036DOI Listing
February 2010

A petunia chorismate mutase specialized for the production of floral volatiles.

Plant J 2010 Jan 7;61(1):145-55. Epub 2009 Oct 7.

Department of Environmental Horticulture, and Plant Molecular and Cellular Biology, University of Florida, Gainesville, FL 32611, USA.

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http://dx.doi.org/10.1111/j.1365-313X.2009.04042.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876350PMC
January 2010

Tissue-specific PhBPBT expression is differentially regulated in response to endogenous ethylene.

J Exp Bot 2008 5;59(3):609-18. Epub 2008 Feb 5.

Department of Environmental Horticulture, University of Florida, Gainesville, FL 32611, USA.

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http://dx.doi.org/10.1093/jxb/erm337DOI Listing
May 2008

Tomato phenylacetaldehyde reductases catalyze the last step in the synthesis of the aroma volatile 2-phenylethanol.

Phytochemistry 2007 Nov 17;68(21):2660-9. Epub 2007 Jul 17.

Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S003194220700381
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http://dx.doi.org/10.1016/j.phytochem.2007.06.005DOI Listing
November 2007

"Apperceptive" alexia in posterior cortical atrophy.

Cortex 2007 Feb;43(2):264-70

Department of Neurology, David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, CA, USA.

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February 2007

Depressive and memory symptoms as presenting features of spinocerebellar ataxia.

J Neuropsychiatry Clin Neurosci 2006 ;18(3):420-2

Department of Neurology, University of California at Los Angeles (UCLA), USA.

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http://dx.doi.org/10.1176/jnp.2006.18.3.420DOI Listing
October 2006

Early-onset dementia: frequency and causes compared to late-onset dementia.

Dement Geriatr Cogn Disord 2006 4;21(2):59-64. Epub 2005 Nov 4.

Department of Neurology, David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1159/000089546DOI Listing
May 2006

Regulation of volatile benzenoid biosynthesis in petunia flowers.

Trends Plant Sci 2006 Jan 12;11(1):20-5. Epub 2005 Oct 12.

Department of Plant Physiology, University of Amsterdam, Swammerdam Institute for Life Sciences, 1098 SM Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.tplants.2005.09.009DOI Listing
January 2006

Ethylene-sensitivity regulates proteolytic activity and cysteine protease gene expression in petunia corollas.

J Exp Bot 2005 Oct 30;56(420):2733-44. Epub 2005 Aug 30.

Department of Horticulture and Crop Science, 1680 Madison Avenue, The Ohio State University OARDC, Wooster, OH 44691, USA.

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http://academic.oup.com/jxb/article/56/420/2733/530539/Ethyl
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http://dx.doi.org/10.1093/jxb/eri266DOI Listing
October 2005

Semantic dementia in multilingual patients.

J Neuropsychiatry Clin Neurosci 2004 ;16(3):381

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http://dx.doi.org/10.1176/jnp.16.3.381DOI Listing
November 2004

Circadian regulation of the PhCCD1 carotenoid cleavage dioxygenase controls emission of beta-ionone, a fragrance volatile of petunia flowers.

Plant Physiol 2004 Nov 29;136(3):3504-14. Epub 2004 Oct 29.

Horticultural Sciences, Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, Florida 32611-0690, USA.

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http://www.plantphysiol.org/cgi/doi/10.1104/pp.104.049718
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http://dx.doi.org/10.1104/pp.104.049718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC527150PMC
November 2004

The central role of PhEIN2 in ethylene responses throughout plant development in petunia.

Plant Physiol 2004 Oct 1;136(2):2900-12. Epub 2004 Oct 1.

Department of Environmental Horticulture , University of Florida, Gainesville, Florida 32611, USA.

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http://dx.doi.org/10.1104/pp.104.046979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC523352PMC
October 2004

Chalcone synthase as a reporter in virus-induced gene silencing studies of flower senescence.

Plant Mol Biol 2004 Jul;55(4):521-30

Department of Environmental Horticulture, University of California Davis, One Shields Avenue, CA 95616, USA.

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http://dx.doi.org/10.1007/s11103-004-0590-7DOI Listing
July 2004

Regulation of methylbenzoate emission after pollination in snapdragon and petunia flowers.

Plant Cell 2003 Dec 20;15(12):2992-3006. Epub 2003 Nov 20.

Department of Horticulture and Landscape Architecture, Purdue University, West Lafayette, Indiana 47907, USA.

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http://dx.doi.org/10.1105/tpc.016766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC282847PMC
December 2003

Speech and language in progressive nonfluent aphasia compared with early Alzheimer's disease.

Neurology 2003 Oct;61(8):1108-13

Department of Neurology, David Geffen School of Medicine, University of California at Los Angeles, USA.

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http://dx.doi.org/10.1212/01.wnl.0000090563.97453.90DOI Listing
October 2003

Overproduction of cytokinins in petunia flowers transformed with P(SAG12)-IPT delays corolla senescence and decreases sensitivity to ethylene.

Plant Physiol 2003 Aug;132(4):2174-83

Department of Horticulture and Landscape Architecture, Colorado State University, Fort Collins, Colorado 80523, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC181301PMC
http://dx.doi.org/10.1104/pp.103.023945DOI Listing
August 2003

Clinicopathologic case report: progressive aphasia in a 77-year-old man.

J Neuropsychiatry Clin Neurosci 2003 ;15(2):231-8

Department of Neurology, University of California, Los Angeles, Medical Center, USA.

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http://dx.doi.org/10.1176/jnp.15.2.231DOI Listing
June 2003

Leaf senescence in a non-yellowing cultivar of chrysanthemum (Dendranthema grandiflora).

Physiol Plant 2001 Apr;111(4):540-544

Environmental Horticulture Department, PO Box 110670, University of Florida, Gainesville, FL 32611, USA; Horticultural Sciences Dept., PO Box 110690, University of Florida, Gainesville, FL 32611, USA.

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April 2001