David Ellison

David Ellison

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David Ellison

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A single-center study of the clinicopathologic correlates of gliomas with a MYB or MYBL1 alteration.

Acta Neuropathol 2019 Oct 8. Epub 2019 Oct 8.

Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s00401-019-02081-1DOI Listing
October 2019

Diffuse Midline Glioma With Osseous Metastases at Diagnosis: A Case Report.

J Pediatr Hematol Oncol 2019 Sep 17. Epub 2019 Sep 17.

Pediatrics, Division of Hematology/Oncology/Blood and Marrow Transplant.

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http://dx.doi.org/10.1097/MPH.0000000000001598DOI Listing
September 2019

Clinical Pharmacology in Diuretic Use.

Authors:
David H Ellison

Clin J Am Soc Nephrol 2019 Aug 1;14(8):1248-1257. Epub 2019 Apr 1.

Departments of Medicine and Physiology and Pharmacology, Oregon Health & Science University, Portland, Oregon; and Renal Section, Veterans Affairs Portland Health Care System, Portland, Oregon

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http://dx.doi.org/10.2215/CJN.09630818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682831PMC
August 2019

Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies.

J Am Soc Nephrol 2019 Aug 28;30(8):1358-1364. Epub 2019 Jun 28.

Epithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland;

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http://dx.doi.org/10.1681/ASN.2019040415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683720PMC
August 2019

Enemy Action in the Distal Convoluted Tubule.

J Am Soc Nephrol 2019 Aug 8;30(8):1345-1348. Epub 2019 Jul 8.

Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

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http://dx.doi.org/10.1681/ASN.2019050475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683721PMC
August 2019

Optical tissue clearing and immunolabeling in kidney research.

Methods Cell Biol 2019 8;154:31-41. Epub 2019 Aug 8.

Division of Nephrology and Hypertension, Oregon Health and Science University, Portland, OR, United States; Renal Section, Veterans Affairs Portland Health Care System, Portland, OR, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mcb.2019.07.001DOI Listing
August 2019

cIMPACT-NOW: a practical summary of diagnostic points from Round 1 updates.

Brain Pathol 2019 07 22;29(4):469-472. Epub 2019 May 22.

Department of Pathology, Amsterdam University Medical Centers/VUmc, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/bpa.12732DOI Listing
July 2019

Dynamic secretome of bone marrow-derived stromal cells reveals a cardioprotective biochemical cocktail.

Proc Natl Acad Sci U S A 2019 Jul 25;116(28):14374-14383. Epub 2019 Jun 25.

Yale Institute of Systems Biology, Yale University, West Haven, CT 06516;

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http://dx.doi.org/10.1073/pnas.1902598116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628676PMC
July 2019

Optical Clearing and Imaging of Immunolabeled Kidney Tissue.

J Vis Exp 2019 Jul 22(149). Epub 2019 Jul 22.

Division of Nephrology and Clinical Immunology, University Hospital RWTH Aachen; Department of Internal Medicine, Nephrology and Transplantation, Erasmus Medical Center.

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http://dx.doi.org/10.3791/60002DOI Listing
July 2019

Data Sets for the Reporting of Tumors of the Central Nervous System.

Arch Pathol Lab Med 2019 Jun 20. Epub 2019 Jun 20.

From the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (Dr Louis); the Department of Pathology, Amsterdam Universities Medical Center/VUmc CCA Brain Tumor Center, Amsterdam, the Netherlands (Dr Wesseling); the Department of Pathology, Princess Máxima Center for Pediatric Oncology, and University Medical Center Utrecht, Utrecht, the Netherlands (Dr Wesseling); Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, United Kingdom (Dr Brandner); the Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, United Kingdom (Dr Brandner); the Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr Brat); the Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee (Dr Ellison); the Department of Radiology, Oncology and Anatomic Pathology, University La Sapienza, Rome, Italy (Dr Giangaspero); IRCCS Neuromed, Pozzilli, Isernia, Italy (Dr Giangaspero); the Department of Pathology, University of Louisville School of Medicine, Louisville, Kentucky (Dr Hattab); the Department of Laboratory Medicine & Pathobiology, The Hospital for Sick Children, Toronto, Ontario, Canada (Dr Hawkins); Project Management Office, Royal College of Pathologists of Australasia, Sydney, Australia (Ms Judge); the Departments of Pathology, Neurology, and Neurosurgery, University of Colorado, Aurora (Dr Kleinschmidt-DeMasters); the Department of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, Tokyo, Japan (Dr Komori); the Department of Pathology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan (Dr Komori); Alfred Anatomical Pathology and NNF, Victorian Brain Bank, Carlton, Victoria, Australia (Dr McLean); Institute of Neuropathology, University Hospital Münster, Münster, Germany (Dr Paulus); Division of Neuropathology, Department of Pathology, University of California, San Francisco (Dr Perry); the Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany (Dr Reifenberger); German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Düsseldorf, Germany (Dr Reifenberger); the Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland (Dr Weller); and the Department of Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom (Dr Rous); ICCR Steering Group Representative (Dr Rous).

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http://dx.doi.org/10.5858/arpa.2018-0565-OADOI Listing
June 2019

Mechanistic Insights into Loop Diuretic Responsiveness in Heart Failure.

Authors:
David H Ellison

Clin J Am Soc Nephrol 2019 May 22;14(5):650-652. Epub 2019 Apr 22.

Departments of Medicine,

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http://dx.doi.org/10.2215/CJN.03590319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500933PMC
May 2019

3D Analysis of Multi-cellular Responses to Chemoattractant Gradients.

J Vis Exp 2019 May 24(147). Epub 2019 May 24.

Department of Biomedical Engineering and Yale Systems Biology Institute, Yale University;

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http://dx.doi.org/10.3791/59226DOI Listing
May 2019

cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAF mutation.

Acta Neuropathol 2019 Apr 8;137(4):683-687. Epub 2019 Mar 8.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00401-019-01987-0DOI Listing
April 2019

Salt-sensitive transcriptome of isolated kidney distal tubule cells.

Physiol Genomics 2019 Apr 15;51(4):125-135. Epub 2019 Mar 15.

Division of Nephrology and Hypertension, Department of Medicine, Oregon Health & Science University , Portland, Oregon.

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http://dx.doi.org/10.1152/physiolgenomics.00119.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485379PMC
April 2019

Rainfall recycling needs to be considered in defining limits to the world's green water resources.

Proc Natl Acad Sci U S A 2019 Apr 9;116(17):8102-8103. Epub 2019 Apr 9.

Independent Researcher, Ellison Consulting, Baar 6340, Switzerland.

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http://dx.doi.org/10.1073/pnas.1903554116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486732PMC
April 2019

Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K excretion.

Am J Physiol Renal Physiol 2019 Mar 9;316(3):F582-F586. Epub 2019 Jan 9.

Department of Pharmacology, New York Medical College, Valhalla, New York.

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http://dx.doi.org/10.1152/ajprenal.00412.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459306PMC
March 2019

Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney.

Am J Physiol Renal Physiol 2019 Feb 28;316(2):F292-F300. Epub 2018 Nov 28.

Department of Anatomy, Charité-Universitätsmedizin Berlin, Berlin , Germany.

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http://dx.doi.org/10.1152/ajprenal.00464.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397373PMC
February 2019

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans.

Am J Physiol Regul Integr Comp Physiol 2019 Feb 6;316(2):R157-R164. Epub 2018 Dec 6.

Oregon Institute of Occupational Health Sciences, Oregon Health & Science University , Portland, Oregon.

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http://dx.doi.org/10.1152/ajpregu.00314.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397357PMC
February 2019

Medulloblastoma.

Nat Rev Dis Primers 2019 02 14;5(1):11. Epub 2019 Feb 14.

Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41572-019-0063-6DOI Listing
February 2019

Structure and evolution of double minutes in diagnosis and relapse brain tumors.

Acta Neuropathol 2019 Jan 28;137(1):123-137. Epub 2018 Sep 28.

Department of Computational Biology, St. Jude Children's Research Hospital, MS1135, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s00401-018-1912-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338707PMC
January 2019

Optical Clearing in the Kidney Reveals Potassium-Mediated Tubule Remodeling.

Cell Rep 2018 12;25(10):2668-2675.e3

Division of Nephrology and Hypertension, Oregon Health & Science University, Portland, OR 97239, USA; Fondation LeDucq Transatlantic Networks of Excellence, Paris 75116, France; Renal Section, Veterans Affairs Portland Health Care System, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.celrep.2018.11.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339512PMC
December 2018

Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.

J Am Soc Nephrol 2018 11 9;29(11):2627-2640. Epub 2018 Oct 9.

Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon;

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http://dx.doi.org/10.1681/ASN.2018030333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218864PMC
November 2018

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.

Am J Physiol Renal Physiol 2018 10 13;315(4):F1006-F1018. Epub 2018 Jun 13.

Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University , Portland, Oregon.

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http://dx.doi.org/10.1152/ajprenal.00602.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230741PMC
October 2018

From bedside to benchmarks: A physician-scientist workforce dashboard for biomedical research institutions.

J Clin Transl Sci 2018 Oct 7;2(5):305-311. Epub 2018 Dec 7.

Clinical and Translational Research, Medicine & Physiology and Pharmacology, Oregon Clinical and Translational Research Institute, Portland VA Medical Center, Oregon Health and Science University, Portland, OR, USA.

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http://dx.doi.org/10.1017/cts.2018.328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390465PMC
October 2018

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC.

Am J Physiol Renal Physiol 2018 09 30;315(3):F734-F745. Epub 2018 May 30.

Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Tlalpan, Mexico City, Mexico.

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https://www.physiology.org/doi/10.1152/ajprenal.00145.2018
Publisher Site
http://dx.doi.org/10.1152/ajprenal.00145.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172580PMC
September 2018

Atypical teratoid/rhabdoid tumor with retained INI1 (SMARCB1) expression and loss of BRG1 (SMARCA4).

Neuropathology 2018 Jun 21;38(3):305-308. Epub 2017 Dec 21.

Department of Neuropathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1111/neup.12452DOI Listing
June 2018

A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.

Cell Rep 2018 06;23(13):3787-3797

Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA; Seattle Tumor Translational Research (STTR), Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA; Alvord Brain Tumor Center, University of Washington, Seattle, WA 98109, USA; Department of Neurosurgery, University of Washington, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411037PMC
June 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension.

Physiol Genomics 2018 02 8;50(2):104-116. Epub 2018 Jan 8.

The Knight Cardiovascular Institute, Oregon Health & Science University , Portland, Oregon.

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http://dx.doi.org/10.1152/physiolgenomics.00111.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867617PMC
February 2018

Outcomes After Reirradiation for Recurrent Pediatric Intracranial Ependymoma.

Int J Radiat Oncol Biol Phys 2018 02 13;100(2):507-515. Epub 2017 Oct 13.

Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2017.10.002DOI Listing
February 2018

Diuretic Treatment in Heart Failure.

N Engl J Med 2018 02;378(7):684-685

Duke University, Durham, NC

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http://dx.doi.org/10.1056/NEJMc1716477DOI Listing
February 2018

Clear cell sarcoma of kidney involving a horseshoe kidney and harboring EGFR internal tandem duplication.

Pediatr Blood Cancer 2017 Nov 25;64(11). Epub 2017 Apr 25.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1002/pbc.26602DOI Listing
November 2017

Diuretic Treatment in Heart Failure.

N Engl J Med 2017 Nov;377(20):1964-1975

From the Oregon Clinical and Translational Research Institute, Oregon Health and Science University and the Veterans Affairs Portland Health Care System, Portland (D.H.E.); and Duke University School of Medicine and Duke Clinical Research Institute, Durham, NC (G.M.F.).

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http://dx.doi.org/10.1056/NEJMra1703100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811193PMC
November 2017

Surgical and molecular considerations in the treatment of pediatric thalamopeduncular tumors.

J Neurosurg Pediatr 2017 Sep 7;20(3):247-255. Epub 2017 Jul 7.

Department of Neurosurgery, Le Bonheur Children's Hospital.

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http://dx.doi.org/10.3171/2017.4.PEDS16668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839469PMC
September 2017

Nephron Remodeling Underlies Hyperkalemia in Familial Hyperkalemic Hypertension.

J Am Soc Nephrol 2017 09 13;28(9):2555-2557. Epub 2017 Jul 13.

Department of Medicine, Oregon Health and Science University, Portland, Oregon; and

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http://dx.doi.org/10.1681/ASN.2017060660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576953PMC
September 2017

Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.

J Clin Oncol 2017 Sep 20;35(25):2934-2941. Epub 2017 Jul 20.

Alvaro Lassaletta, Michal Zapotocky, Matthew Mistry, Vijay Ramaswamy, Marion Honnorat, Rahul Krishnatry, Ana Guerreiro Stucklin, Nataliya Zhukova, Anthony Arnoldo, Scott Ryall, Catriona Ling, Tara McKeown, Jim Loukides, James T. Rutka, Peter Dirks, Michael D. Taylor, Shiyi Chen, Ute Bartels, Annie Huang, Eric Bouffet, Cynthia Hawkins, and Uri Tabori, The Hospital for Sick Children, Toronto; Adam Fleming, McMaster Children's Hospital, McMaster University, Hamilton; Shayna Zelcer, Children's Hospital of Western Ontario, London, Ontario; David Eisenstat and Bev Wilson, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta; Anne Sophie Carret, Hospital Sainte Justine; Nada Jabado, McGill University, Montreal; Valerie Larouche, Centre Hospitalier Universitaire de Québec, Québec City, Quebec, Canada; Ofelia Cruz and Carmen de Torres, Hospital Sant Joan de Déu, Barcelona, Spain; Cheng-Ying Ho, University of Maryland School of Medicine, Baltimore, MD; Roger J. Packer, Children's National Health System, Washington, DC; Ruth Tatevossian, Ibrahim Qaddoumi, Julie H. Harreld, James D. Dalton, and David W. Ellison, St Jude Children's Research Hospital, Memphis, TN; Jean Mulcahy-Levy and Nicholas Foreman, Children's Hospital Colorado, Aurora, CO; Matthias A. Karajannis, Shiyang Wang, and Matija Snuderl, New York University Langone Medical Center, New York, NY; Amulya Nageswara Rao and Caterina Giannini, The Mayo Clinic, Rochester, MN; Mark Kieran and Keith L. Ligon, Dana-Farber Cancer Institute, Boston Children's Hospital, Boston, MA; Maria Luisa Garre, Paolo Nozza, Samantha Mascelli, and Alessandro Raso, Istituto Giannina Gaslini, Genoa, Italy; Sabine Mueller and Theodore Nicolaides, University of California, San Francisco, San Francisco, CA; Karen Silva and Romain Perbet, Hospices Civils de Lyon; Alexandre Vasiljevic, Cécile Faure Conter, and Didier Frappaz, Institute of Pediatric Hematology and Oncology, Lyon, France; Sarah Leary and Courtney Crane, Seattle Children's Hospital, Seattle, WA; Aden Chan and Ho-Keung Ng, The Chinese University of Hong Kong, Hong Kong; Zhi-Feng Shi and Ying Mao, Huashan Hospital, Fudan University, Shanghai, People's Republic of China; Elizabeth Finch, University of North Carolina, School of Medicine, Chapel Hill, NC; Peter Hauser, Semmelweis University, Budapest, Hungary; and David Sumerauer and Lenka Krskova, University Hospital Motol, Charles University, 2nd Medical School, Prague, Czech Republic.

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http://dx.doi.org/10.1200/JCO.2016.71.8726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791837PMC
September 2017

Treatment of Disorders of Sodium Balance in Chronic Kidney Disease.

Authors:
David H Ellison

Adv Chronic Kidney Dis 2017 09;24(5):332-341

Department of Medicine, Oregon Health & Science University, Portland, Oregon; Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, Oregon; and Renal Section, VA Portland Health Care System, Portland, Oregon. Electronic address:

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http://dx.doi.org/10.1053/j.ackd.2017.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685178PMC
September 2017

Low-grade spinal glioneuronal tumors with BRAF gene fusion and 1p deletion but without leptomeningeal dissemination.

Acta Neuropathol 2017 07 25;134(1):159-162. Epub 2017 May 25.

Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105-3678, USA.

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http://dx.doi.org/10.1007/s00401-017-1728-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848506PMC
July 2017

Potassium Sensing by Renal Distal Tubules Requires Kir4.1.

J Am Soc Nephrol 2017 Jun 4;28(6):1814-1825. Epub 2017 Jan 4.

Department of Pharmacology, New York Medical College, Valhalla, New York; and

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http://dx.doi.org/10.1681/ASN.2016090935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461801PMC
June 2017

Genetic Risk, Lifestyle, and Coronary Artery Disease.

Authors:
David H Ellison

N Engl J Med 2017 03;376(12):1194

Oregon Health and Science University, Portland, OR

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http://dx.doi.org/10.1056/NEJMc1700362DOI Listing
March 2017

WNK Kinase Signaling in Ion Homeostasis and Human Disease.

Cell Metab 2017 02;25(2):285-299

Departments of Neurosurgery, Pediatrics, and Cellular & Molecular Physiology, Centers for Mendelian Genomics, Yale School of Medicine, New Haven, CT 06477, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.01.007DOI Listing
February 2017

Molecular pathology of paediatric central nervous system tumours.

J Pathol 2017 Jan 10;241(2):159-172. Epub 2016 Nov 10.

Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1002/path.4813DOI Listing
January 2017

Diuretic Resistance.

Am J Kidney Dis 2017 Jan 1;69(1):136-142. Epub 2016 Nov 1.

Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University and VA Portland Health Care System, Portland, OR. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2016.08.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182087PMC
January 2017

PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.

Cancer Res 2017 01 4;77(1):123-133. Epub 2016 Nov 4.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214974PMC
January 2017

Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Kidney Int 2017 01;91(1):24-33

Hôpital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, Centre d'Investigation Clinique, Paris, France; Centre de Référence des Maladies Rénales Héréditaires de l'Enfant et de l'Adulte, Paris, France.

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http://dx.doi.org/10.1016/j.kint.2016.09.046DOI Listing
January 2017

Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases.

Annu Rev Physiol 2016 ;78:367-89

Molecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, Mexico City 14080, Mexico; email:

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http://dx.doi.org/10.1146/annurev-physiol-021115-105431DOI Listing
December 2016

Direct and Indirect Mineralocorticoid Effects Determine Distal Salt Transport.

J Am Soc Nephrol 2016 08 28;27(8):2436-45. Epub 2015 Dec 28.

Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon; and Renal Section, Veterans Affairs Portland Health Care System, Portland, Oregon

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http://dx.doi.org/10.1681/ASN.2015070815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978056PMC
August 2016

Quantitative imaging analysis of posterior fossa ependymoma location in children.

Childs Nerv Syst 2016 Aug 27;32(8):1441-7. Epub 2016 Apr 27.

Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 262 Danny Thomas Place (MS 220), Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s00381-016-3092-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967400PMC
August 2016

Multi-organ Mapping of Cancer Risk.

Cell 2016 Aug;166(5):1132-1146.e7

Department of Oncology and CRUK Cambridge Institute, Robinson Way, Cambridge CB2 0RE, England. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067024PMC
http://dx.doi.org/10.1016/j.cell.2016.07.045DOI Listing
August 2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 07 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

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http://dx.doi.org/10.1200/JCO.2015.65.7825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962737PMC
July 2016

Pediatric gliomas as neurodevelopmental disorders.

Glia 2016 Jun 6;64(6):879-95. Epub 2015 Dec 6.

Department of Neurology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1002/glia.22945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833573PMC
June 2016

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Acta Neuropathol 2016 06 9;131(6):803-20. Epub 2016 May 9.

Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1007/s00401-016-1545-1DOI Listing
June 2016

Potassium and Its Discontents: New Insight, New Treatments.

J Am Soc Nephrol 2016 Apr 28;27(4):981-9. Epub 2015 Oct 28.

Molecular Physiology Unit, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán and Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Tlalpan, Mexico City, Mexico.

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http://dx.doi.org/10.1681/ASN.2015070751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814195PMC
April 2016

Case Report of Spontaneous Resolution of a Congenital Glioblastoma.

Pediatrics 2016 Apr 15;137(4). Epub 2016 Mar 15.

Kids Cancer Centre, Sydney Children's Hospital, High St, Randwick, Australia; School of Women's and Children's Health, University of New South Wales, Randwick, Australia

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http://dx.doi.org/10.1542/peds.2015-1241DOI Listing
April 2016

Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis.

Proc Natl Acad Sci U S A 2016 Feb 20;113(6):E679-88. Epub 2016 Jan 20.

Department of Biomedical Engineering and Yale Systems Biology Institute, Yale University, New Haven, CT 06520;

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http://dx.doi.org/10.1073/pnas.1516503113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760786PMC
February 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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http://www.cell.com/cell/pdf/S0092-8674(16)00055-6.pdf
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http://www.cell.com/cms/attachment/2048488015/2058390163/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741600055
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http://dx.doi.org/10.1016/j.cell.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139621PMC
February 2016

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.

Biochem Biophys Res Commun 2016 Jan 23;469(1):44-48. Epub 2015 Nov 23.

Division of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, OR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.11.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695252PMC
January 2016

Germline Mutations in Predisposition Genes in Pediatric Cancer.

N Engl J Med 2015 Dec 18;373(24):2336-2346. Epub 2015 Nov 18.

Departments of Computational Biology (J.Z., G.W., M.N.E., D.H., X.M., X.Z., M.R.W., X.C., M.R., A.P., J.B.B., S.W.), Oncology (M.F.W., T.A.G., R.B.M., S.H.-D., R.N., E.Q., A.G., A.S.P., C.-H.P., K.E.N.), and Pathology (T.A.G., M.R.W., S.A.S., D.W.E., C.-H.P., J.R.D.) and the Pediatric Cancer Genome Project (J.Z., M.F.W., G.W., M.N.E., T.A.G., J.E., X.M., D.A.Y., B.V., X.C., R.B.M., S.H.-D., R.N., E.Q., S.A.S., M.R., A.P., J.B.B., S.W., M.S.W., A.G., D.W.E., A.S.P., C.-H.P., K.E.N., J.R.D.), St. Jude Children's Research Hospital, Memphis, TN; and the Department of Genetics and McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis (L.D., E.R.M., R.K.W.).

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http://dx.doi.org/10.1056/NEJMoa1508054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734119PMC
December 2015

Outstanding translational science at American Society of Hypertension 2015.

Authors:
David H Ellison

J Am Soc Hypertens 2015 Nov 8;9(11):828-30. Epub 2015 Sep 8.

Division of Nephrology and Hypertension, Oregon Clinical and Translational Research Institute, Oregon Health and Science University, Portland, OR, USA; Portland VA Medical Center, Portland, OR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jash.2015.08.016DOI Listing
November 2015