David E Sosnovik

David E Sosnovik

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David E Sosnovik

Publications by authors named "David E Sosnovik"

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Alteration in ventricular pressure stimulates cardiac repair and remodeling.

J Mol Cell Cardiol 2019 Aug 17;133:174-187. Epub 2019 Jun 17.

Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America; Cardiovascular Research Institute, Stanford University School of Medicine, Stanford, CA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698254PMC
August 2019

Imaging the Microstructure of the Human Fetal Heart.

Circ Cardiovasc Imaging 2018 10;11(10):e008298

Department of Cardiology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, MA (T.G.).

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https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.118.0082
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http://dx.doi.org/10.1161/CIRCIMAGING.118.008298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221466PMC
October 2018

Noninvasive Tissue Characterization of Post-Infarction Myocardium.

JACC Cardiovasc Imaging 2018 Sep;11(9):1257-1259

Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcmg.2017.11.040DOI Listing
September 2018

A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism.

Radiology 2018 03 8;286(3):865-872. Epub 2017 Nov 8.

From the Athinoula A. Martinos Center for Biomedical Imaging and the Institute for Innovation in Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 149 Thirteenth St, Suite 2301, Charlestown, MA 02129.

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http://dx.doi.org/10.1148/radiol.2017170977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831267PMC
March 2018

Multiplexed Optical Imaging of Energy Substrates Reveals That Left Ventricular Hypertrophy Is Associated With Brown Adipose Tissue Activation.

Circ Cardiovasc Imaging 2018 03;11(3):e007007

From the Cardiovascular Medicine Section, Department of Medicine, Boston University Medical Center, MA (M.P., D.C., I.L., W.S.C.); Cardiovascular Research Center (M.P., H.H.C., D.E.S.) and Martinos Center for Biomedical Imaging, Department of Radiology (M.P., H.H.C., Y.-C.I.C., C.R., L.J., D.E.S.), Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1161/CIRCIMAGING.117.007007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908227PMC
March 2018

PET/MR Imaging of Atherosclerosis: Insights Into Atheroma Structure and Biology.

JACC Cardiovasc Imaging 2018 02;11(2 Pt 2):302-304

Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcmg.2017.12.004DOI Listing
February 2018

Myocardial Scar Delineation Using Diffusion Tensor Magnetic Resonance Tractography.

J Am Heart Assoc 2018 02 2;7(3). Epub 2018 Feb 2.

Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/JAHA.117.007834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850260PMC
February 2018

Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury.

Theranostics 2017 8;7(4):814-825. Epub 2017 Feb 8.

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston MA;; Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston MA.

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http://dx.doi.org/10.7150/thno.17366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381246PMC
October 2017

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.

Proc Natl Acad Sci U S A 2017 05 8;114(21):E4241-E4250. Epub 2017 May 8.

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA 02114;

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http://dx.doi.org/10.1073/pnas.1621511114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448167PMC
May 2017

Diffusion MRI in the heart.

NMR Biomed 2017 Mar 20;30(3). Epub 2015 Oct 20.

Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1002/nbm.3426
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http://dx.doi.org/10.1002/nbm.3426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333463PMC
March 2017

Diffusion Tractography of the Entire Left Ventricle by Using Free-breathing Accelerated Simultaneous Multisection Imaging.

Radiology 2017 03 28;282(3):850-856. Epub 2016 Sep 28.

From the Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology (C.M., T.G.R., S.F.C., K.S., D.E.S.), and Cardiovascular Research Center, Cardiology Division (D.E.S.), Massachusetts General Hospital, Harvard Medical School, 149 13th St, Charlestown, MA 02129; Department of Computer Science, Institute of Mathematics and Statistics, University of São Paulo, São Paulo, Brazil (M.P.J.); and Siemens Healthcare, Charlestown, Mass (H.B.).

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http://dx.doi.org/10.1148/radiol.2016152613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318239PMC
March 2017

Microstructural characterization of myocardial infarction with optical coherence tractography and two-photon microscopy.

Physiol Rep 2016 09;4(18)

Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital Harvard Medical School, Charlestown, Massachusetts Cardiovascular Research Center, Department of Medicine, Massachusetts General Hospital Harvard Medical School, Charlestown, Massachusetts

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037910PMC
http://dx.doi.org/10.14814/phy2.12894DOI Listing
September 2016

Dual-phase cardiac diffusion tensor imaging with strain correction.

PLoS One 2014 5;9(9):e107159. Epub 2014 Sep 5.

Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107159PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156436PMC
February 2016

Imaging Lymphoid Cell Death In Vivo During Polymicrobial Sepsis.

Crit Care Med 2015 Nov;43(11):2303-12

1Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA. 2Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA. 3Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA.

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http://dx.doi.org/10.1097/CCM.0000000000001254DOI Listing
November 2015

Heat-Induced Radiolabeling of Nanoparticles for Monocyte Tracking by PET.

Angew Chem Int Ed Engl 2015 Oct 14;54(44):13002-6. Epub 2015 Sep 14.

Center for Advanced Medical Imaging Sciences, Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114 (USA).

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http://dx.doi.org/10.1002/anie.201505525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754124PMC
October 2015

Seeing What We Build--The Need for New Imaging Techniques in Myocardial Regeneration.

Authors:
David E Sosnovik

J Am Heart Assoc 2015 Jul 27;4(7). Epub 2015 Jul 27.

Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (D.E.S.) Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA (D.E.S.).

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http://dx.doi.org/10.1161/JAHA.115.002306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608098PMC
July 2015

Cytoprotective nanoparticles by conjugation of a polyhis tagged annexin V to a nanoparticle drug.

Nanoscale 2015 Feb;7(6):2255-9

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA 02129, USA.

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http://dx.doi.org/10.1039/c4nr06861kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312233PMC
February 2015

In vivo nanoparticle assessment of pathological endothelium predicts the development of inflow stenosis in murine arteriovenous fistula.

Arterioscler Thromb Vasc Biol 2015 Jan 13;35(1):189-96. Epub 2014 Nov 13.

From the Cardiovascular Research Center (J.C., C.W.K., D.E.S., F.A.J.), Division of Cardiology (P.L.), Division of Nephrology (J.C., R.I.T.), Center for System Biology (J.R.M.), Martinos Center for Biomedical Imaging (D.E.S.), and Wellman Center for Photomedicine (F.A.J.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1161/ATVBAHA.114.304483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270948PMC
January 2015

Diffusion MRI tractography of the developing human fetal heart.

PLoS One 2013 26;8(8):e72795. Epub 2013 Aug 26.

Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072795PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753231PMC
June 2014

Microstructural impact of ischemia and bone marrow-derived cell therapy revealed with diffusion tensor magnetic resonance imaging tractography of the heart in vivo.

Circulation 2014 Apr 11;129(17):1731-41. Epub 2014 Mar 11.

From Martinos Center for Biomedical Imaging, Department of Radiology (D.E.S., C.M., S.H., H.H.C., G.D., R.W., W.J.K., V.J.W.), and Cardiovascular Research Center, Cardiology Division (D.E.S., H.H.C., W.J.K.), Massachusetts General Hospital, Harvard Medical School, Boston, MA; Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland (C.T.S., S.K.); Cardiac Muscle Research Laboratory, Divisions of Cardiology and Genetics, Brigham and Woman's Hospital, Harvard Medical School, Boston, MA (S.N., J.G., R.L.); and Department of Computer Science, Institute of Mathematics and Statistics, University of São Paulo, São Paulo, Brazil (M.P.J.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034455PMC
April 2014

Role of extracellular RNA and TLR3-Trif signaling in myocardial ischemia-reperfusion injury.

J Am Heart Assoc 2014 Jan 3;3(1):e000683. Epub 2014 Jan 3.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital.

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http://dx.doi.org/10.1161/JAHA.113.000683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959703PMC
January 2014

Molecular magnetic resonance imaging of pulmonary fibrosis in mice.

Am J Respir Cell Mol Biol 2013 Dec;49(6):1120-6

1 A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts.

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http://dx.doi.org/10.1165/rcmb.2013-0039OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931113PMC
December 2013

Imaging DNA with fluorochrome bearing metals.

Inorg Chem 2013 Nov 6;52(21):12216-22. Epub 2013 May 6.

Center for Translational Nuclear Medicine and Molecular Imaging, ‡Martinos Center for Biomedical Imaging, Department of Radiology, and §Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Harvard Medical School , Boston, Massachusetts 02114, United States.

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http://dx.doi.org/10.1021/ic400404gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818342PMC
November 2013

Fluorescent and radiolabeled triphenylphosphonium probes for imaging mitochondria.

Chem Commun (Camb) 2013 Nov;49(88):10361-3

Center for Advanced Medical Imaging Sciences, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1039/c3cc45802dDOI Listing
November 2013

Adult cardiac progenitor cell aggregates exhibit survival benefit both in vitro and in vivo.

PLoS One 2012 30;7(11):e50491. Epub 2012 Nov 30.

Division of Cardiology and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050491PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511575PMC
May 2013

Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo.

Circ Cardiovasc Imaging 2013 May 28;6(3):441-7. Epub 2013 Mar 28.

Martinos Center for Biomedical Imaging, Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.112.000074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805276PMC
May 2013

Fluorochrome-functionalized nanoparticles for imaging DNA in biological systems.

ACS Nano 2013 Mar 7;7(3):2032-41. Epub 2013 Feb 7.

Center for Translational Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, United States.

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http://dx.doi.org/10.1021/nn305962nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800685PMC
March 2013

Molecular MRI of the Cardiovascular System in the Post-NSF Era.

Curr Cardiovasc Imaging Rep 2013 Feb 29;6(1):61-68. Epub 2012 Nov 29.

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston MA ; Department of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston MA ; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston MA.

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http://dx.doi.org/10.1007/s12410-012-9182-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597126PMC
February 2013

Theranostic Imaging of the Kinases and Proteases that Modulate Cell Death and Survival.

Theranostics 2012 8;2(2):148-55. Epub 2012 Feb 8.

1. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston MA.

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http://www.thno.org/v02p0148.htm
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http://dx.doi.org/10.7150/thno.4077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296472PMC
October 2012

Optical coherence tractography using intrinsic contrast.

Opt Lett 2012 Sep;37(18):3882-4

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691965PMC
http://dx.doi.org/10.1364/ol.37.003882DOI Listing
September 2012

Science to practice: how will myocardial inflammation be imaged with MR imaging?

Radiology 2012 Aug;264(2):309-11

Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1148/radiol.12121094DOI Listing
August 2012

Fluorochrome-functionalized magnetic nanoparticles for high-sensitivity monitoring of the polymerase chain reaction by magnetic resonance.

Angew Chem Int Ed Engl 2012 Jul 8;51(28):6904-7. Epub 2012 Jun 8.

Center for Translational Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Charlestown, 02129, USA.

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http://dx.doi.org/10.1002/anie.201201661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477829PMC
July 2012

In vivo fluorescence lifetime detection of an activatable probe in infarcted myocardium.

J Biomed Opt 2012 May;17(5):056001

Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1117/1.JBO.17.5.056001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381023PMC
May 2012

Protective effect of the apoptosis-sensing nanoparticle AnxCLIO-Cy5.5.

Nanomedicine 2012 Apr 24;8(3):291-8. Epub 2011 Jun 24.

Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S154996341100265
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http://dx.doi.org/10.1016/j.nano.2011.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319055PMC
April 2012

A Novel Transgenic Mouse Model of Cardiac Hypertrophy and Atrial Fibrillation.

J Atr Fibrillation 2012 Feb-Mar;4(5):415. Epub 2012 Feb 2.

Cardiovascular Institute, Beth Israel Deaconess Medical Center, 3 Blackfan Circle, CLS 9, Boston MA 02215.

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http://dx.doi.org/10.4022/jafib.415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521534PMC
February 2012

Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium.

Circ Cardiovasc Imaging 2011 Nov 11;4(6):729-37. Epub 2011 Aug 11.

Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.111.966374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370828PMC
November 2011

Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4.

J Biol Chem 2011 Sep 20;286(36):31308-19. Epub 2011 Jul 20.

Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1074/jbc.M111.246124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173057PMC
September 2011

From molecules to myofibers: multiscale imaging of the myocardium.

J Cardiovasc Transl Res 2011 Aug 4;4(4):493-503. Epub 2011 Jun 4.

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s12265-011-9284-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370890PMC
August 2011

Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging?

Radiology 2011 Aug;260(2):309-10

Center for Systems Biology, Massachusetts General Hospital, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1148/radiol.11111017DOI Listing
August 2011

Imaging of apoptosis in the heart with nanoparticle technology.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2011 Jan-Feb;3(1):86-99

Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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http://doi.wiley.com/10.1002/wnan.115
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http://dx.doi.org/10.1002/wnan.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086683PMC
July 2011

Cardiomyocyte death: insights from molecular and microstructural magnetic resonance imaging.

Pediatr Cardiol 2011 Mar 6;32(3):290-6. Epub 2011 Feb 6.

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 5404, 149 13th Street, Charlestown, MA 02129, USA.

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http://link.springer.com/10.1007/s00246-011-9894-y
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http://dx.doi.org/10.1007/s00246-011-9894-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078825PMC
March 2011

Multimodality imaging of myocardial injury and remodeling.

J Nucl Med 2010 May 15;51 Suppl 1:107S-121S. Epub 2010 Apr 15.

Departments of Medicine and Radiology, University of Virginia Health System, 1215 Lee St., Box 800170, Charlottesville, VA 22908, USA.

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http://jnm.snmjournals.org/content/51/Supplement_1/107S.full
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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.109.068221
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http://dx.doi.org/10.2967/jnumed.109.068221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078824PMC
May 2010

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.

J Am Coll Cardiol 2010 Apr;55(15):1629-38

Center for Systems Biology, Simches Research Building, Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1016/j.jacc.2009.08.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852892PMC
April 2010

Molecular and Microstructural Imaging of the Myocardium.

Curr Cardiovasc Imaging Rep 2010 Feb;3(1):26-33

CNY, Massachusetts General Hospital, 5416, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1007/s12410-010-9007-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916196PMC
February 2010

Diffusion MR tractography of the heart.

J Cardiovasc Magn Reson 2009 Nov 13;11:47. Epub 2009 Nov 13.

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston MA, USA.

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http://dx.doi.org/10.1186/1532-429X-11-47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781805PMC
November 2009

Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia.

Circ Cardiovasc Imaging 2009 Nov 29;2(6):460-7. Epub 2009 Sep 29.

Center for Molecular Imaging Research, the Cardiology Division, Martinos Center for Biomedical Imaging, and the Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston. Mass, USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.109.859678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780438PMC
November 2009

Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure.

Circ Cardiovasc Imaging 2009 Nov 1;2(6):468-75. Epub 2009 Sep 1.

Center for Molecular Imaging Research, the Cardiology Division, and Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, Masss, USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.109.863779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782621PMC
November 2009

A DNA-binding Gd chelate for the detection of cell death by MRI.

Chem Commun (Camb) 2009 Aug 12(29):4444-6. Epub 2009 Jun 12.

Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1039/b907375bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754278PMC
August 2009

Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques?

Authors:
David E Sosnovik

Radiology 2009 May;251(2):309-10

Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 13th St, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1148/radiol.2512090268DOI Listing
May 2009

MRI of a novel murine working heart transplant model.

Circ Heart Fail 2009 May;2(3):272-4

Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Simches Research Building, Boston, Mass, USA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.109.852707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733535PMC
May 2009

Diffusion spectrum MRI tractography reveals the presence of a complex network of residual myofibers in infarcted myocardium.

Circ Cardiovasc Imaging 2009 May 19;2(3):206-12. Epub 2009 Mar 19.

Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass., USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.108.815050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760045PMC
May 2009

Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach.

Authors:
David E Sosnovik

Curr Cardiovasc Imaging Rep 2009 Feb;2(1):33-39

Center for Molecular Imaging Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1007/s12410-009-0005-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808047PMC
February 2009

Multimodality cardiovascular molecular imaging, Part II.

Circ Cardiovasc Imaging 2009 Jan;2(1):56-70

Centers for Systems Biology and Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.108.839092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760054PMC
January 2009

Off-resonance angiography: a new method to depict vessels--phantom and rabbit studies.

Radiology 2008 Nov 9;249(2):501-9. Epub 2008 Sep 9.

Russell H. Morgan Department of Radiology and Radiological Science, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1148/radiol.2491071706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657865PMC
November 2008

Targeted imaging of myocardial damage.

Nat Clin Pract Cardiovasc Med 2008 Aug;5 Suppl 2:S63-70

Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, MA 02129, USA.

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http://dx.doi.org/10.1038/ncpcardio1115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597275PMC
August 2008

Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging.

NMR Biomed 2008 Jun;21(5):453-63

Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1002/nbm.1209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629945PMC
June 2008

A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla.

Magn Reson Med 2008 Jun;59(6):1431-9

Department of Radiology, A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1002/mrm.21598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2548273PMC
June 2008

MR-optical imaging of cardiovascular molecular targets.

Basic Res Cardiol 2008 Mar;103(2):87-94

Center for Molecular Imaging Research, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1007/s00395-008-0707-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664635PMC
March 2008

Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications.

Basic Res Cardiol 2008 Mar;103(2):122-30

Center for Molecular Imaging Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.

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http://dx.doi.org/10.1007/s00395-008-0710-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597271PMC
March 2008

Transglutaminase activity in acute infarcts predicts healing outcome and left ventricular remodelling: implications for FXIII therapy and antithrombin use in myocardial infarction.

Eur Heart J 2008 Feb;29(4):445-54

Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Room 5406, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1093/eurheartj/ehm558DOI Listing
February 2008

Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential.

Authors:
David E Sosnovik

Top Magn Reson Imaging 2008 Feb;19(1):59-68

Department of Cardiology, Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.

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http://dx.doi.org/10.1097/RMR.0b013e318176c57bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597277PMC
February 2008

Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis.

Circulation 2008 Jan 24;117(3):379-87. Epub 2007 Dec 24.

Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.741181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663426PMC
January 2008

Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm.

J Magn Reson Imaging 2007 Aug;26(2):279-87

Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1002/jmri.20966DOI Listing
August 2007

High-resolution imaging of murine myocardial infarction with delayed-enhancement cine micro-CT.

Am J Physiol Heart Circ Physiol 2007 Jun 23;292(6):H3172-8. Epub 2007 Feb 23.

Center for Molecular Imaging Research, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1152/ajpheart.01307.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680216PMC
June 2007

Molecular magnetic resonance imaging in cardiovascular medicine.

Circulation 2007 Apr;115(15):2076-86

Center for Molecular Imaging Research, Massachusetts General Hospital, 149 13th St, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.658930DOI Listing
April 2007

Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo.

Circulation 2007 Mar 5;115(11):1384-91. Epub 2007 Mar 5.

Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.663351DOI Listing
March 2007

Emerging concepts in molecular MRI.

Curr Opin Biotechnol 2007 Feb 28;18(1):4-10. Epub 2006 Nov 28.

Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.copbio.2006.11.001DOI Listing
February 2007

Feasibility and optimization of aortic valve planimetry with MDCT.

AJR Am J Roentgenol 2007 Feb;188(2):356-60

Department of Radiology, Massachusetts General Hospital, 165 Cambridge St., Ste. 400, Boston, MA 02114, USA.

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http://dx.doi.org/10.2214/AJR.06.0232DOI Listing
February 2007

Molecular imaging of myocardial infarction.

J Mol Cell Cardiol 2006 Dec 24;41(6):921-33. Epub 2006 Oct 24.

Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2006.09.008DOI Listing
December 2006

Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.

Circulation 2006 Oct 25;114(14):1504-11. Epub 2006 Sep 25.

Center for Molecular Imaging Research, Massachusetts General Hospital, Boston, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.646380DOI Listing
October 2006

Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle.

Magn Reson Med 2005 Sep;54(3):718-24

Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/mrm.20617DOI Listing
September 2005

Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter.

Med Phys 2005 Feb;32(2):418-26

Washington University, St Louis, Missouri 63130, USA.

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http://doi.wiley.com/10.1118/1.1852793
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http://dx.doi.org/10.1118/1.1852793DOI Listing
February 2005

Value of fat suppression in the MRI evaluation of suspected arrhythmogenic right ventricular dysplasia.

AJR Am J Roentgenol 2004 Mar;182(3):587-91

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 100 Charles River Plaza, Ste. 400, Boston, MA 02114, USA.

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http://dx.doi.org/10.2214/ajr.182.3.1820587DOI Listing
March 2004

Measurement of radial artery contrast intensity to assess cardiac microbubble behavior.

J Am Soc Echocardiogr 2003 Dec;16(12):1267-73

Cardiac Ultrasound laboratory, Massachusetts Genral Hospital, Harvard Medical School, Boston, 02114, USA.

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http://dx.doi.org/10.1067/j.echo.2003.08.009DOI Listing
December 2003

Non-invasive imaging of plaque vulnerability: an important tool for the assessment of agents to stabilise atherosclerotic plaques.

Expert Opin Investig Drugs 2002 May;11(5):693-704

Division of Cardiology, CIMIT Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1517/13543784.11.5.693DOI Listing
May 2002