David E Reichert

Site-specific effects of neurosteroids on GABA receptor activation and desensitization.

Authors:

Yusuke Sugasawa Wayland Wl Cheng John R Bracamontes Zi-Wei Chen Lei Wang Allison L Germann Spencer R Pierce Thomas C Senneff Kathiresan Krishnan David E Reichert Douglas F Covey Gustav Akk Alex S Evers

Elife 2020 09 21;9. Epub 2020 Sep 21.

Department of Anesthesiology, Washington University in St. Louis, St. Louis, United States.

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September 2020

Analysis of Modulation of the 1 GABA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites.

Authors:

Allison L Germann David E Reichert Ariel B Burbridge Spencer R Pierce Alex S Evers Joe Henry Steinbach Gustav Akk

Mol Pharmacol 2020 10 16;98(4):280-291. Epub 2020 Jul 16.

Departments of Anesthesiology (A.L.G., A.B.B., S.R.P., A.S.E., J.H.S., G.A.) and Radiology (D.E.R.) and the Taylor Family Institute for Innovative Psychiatric Research (D.E.R., A.S.E., J.H.S., G.A.), Washington University School of Medicine, St. Louis, Missouri

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October 2020

The molecular determinants of neurosteroid binding in the GABA(A) receptor.

Authors:

Yusuke Sugasawa John R Bracamontes Kathiresan Krishnan Douglas F Covey David E Reichert Gustav Akk Qiang Chen Pei Tang Alex S Evers Wayland W L Cheng

J Steroid Biochem Mol Biol 2019 09 28;192:105383. Epub 2019 May 28.

Department of Anesthesiology, Washington University in St. Louis, St. Louis, MO 63110, USA. Electronic address:

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September 2019

Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation.

ACS Appl Mater Interfaces 2019 Jun 22;11(22):19669-19678. Epub 2019 May 22.

Mallinckrodt Institute of Radiology , Washington University , St. Louis , Missouri 63110 , United States.

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June 2019

Multiple functional neurosteroid binding sites on GABAA receptors.

Authors:

Zi-Wei Chen John R Bracamontes Melissa M Budelier Allison L Germann Daniel J Shin Krishnan Kathiresan Ming-Xing Qian Brad Manion Wayland W L Cheng David E Reichert Gustav Akk Douglas F Covey Alex S Evers

PLoS Biol 2019 03 7;17(3):e3000157. Epub 2019 Mar 7.

Department of Anesthesiology, Washington University in St Louis, St Louis, Missouri, United States of America.

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March 2019

"Click Chip" Conjugation of Bifunctional Chelators to Biomolecules.

Authors:

Joseph J Whittenberg Hairong Li Haiying Zhou Jan Koziol Amit V Desai David E Reichert Paul J A Kenis

Bioconjug Chem 2017 04 9;28(4):986-994. Epub 2017 Feb 9.

Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

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April 2017

A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons.

Authors:

Christine Emnett Hairong Li Xiaoping Jiang Ann Benz Joseph Boggiano Sara Conyers David F Wozniak Charles F Zorumski David E Reichert Steven Mennerick

Sci Rep 2016 12 16;6:38808. Epub 2016 Dec 16.

Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110, USA.

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December 2016

Microfluidic Preparation of a 89Zr-Labeled Trastuzumab Single-Patient Dose.

Authors:

Brian D Wright Joseph Whittenberg Amit Desai Christina DiFelice Paul J A Kenis Suzanne E Lapi David E Reichert

J Nucl Med 2016 05 14;57(5):747-52. Epub 2016 Jan 14.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri; and

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May 2016

Bitropic D3 Dopamine Receptor Selective Compounds as Potential Antipsychotics.

Authors:

Robert R Luedtke Claudia Rangel-Barajas Mahinder Malik David E Reichert R H Mach

Curr Pharm Des 2015 ;21(26):3700-24

Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, TX, USA.

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June 2016

Development of a microfluidic "click chip" incorporating an immobilized Cu(I) catalyst.

Authors:

Hairong Li Joseph J Whittenberg Haiying Zhou David Ranganathan Amit V Desai Jan Koziol Dexing Zeng Paul J A Kenis David E Reichert

RSC Adv 2015 Jan;5(8):6142-6150

Radiological Sciences Division, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Blvd., St. Louis, MO 63110, USA.

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January 2015

Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands.

Authors:

Xin Peng Qi Wang Yogesh Mishra Jinbin Xu David E Reichert Maninder Malik Michelle Taylor Robert R Luedtke Robert H Mach

Bioorg Med Chem Lett 2015 Feb 17;25(3):519-23. Epub 2014 Dec 17.

Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, United States; Department of Cell Biology & Physiology, Washington University School of Medicine, St. Louis, MO 63110, United States; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, United States. Electronic address:

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February 2015

Thiolene and SIFEL-based Microfluidic Platforms for Liquid-Liquid Extraction.

Authors:

Sachit Goyal Amit V Desai Robert W Lewis David R Ranganathan Hairong Li Dexing Zeng David E Reichert Paul J A Kenis

Sens Actuators B Chem 2014 Jan;190:634-644

Department of Chemical & Biomolecular Engineering, University of Illinois, Urbana-Champaign, Urbana, IL 61801, USA.

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January 2014

Triazine-based tool box for developing peptidic PET imaging probes: syntheses, microfluidic radiolabeling, and structure-activity evaluation.

Authors:

Hairong Li Haiying Zhou Stephanie Krieger Jesse J Parry Joseph J Whittenberg Amit V Desai Buck E Rogers Paul J A Kenis David E Reichert

Bioconjug Chem 2014 Apr 4;25(4):761-72. Epub 2014 Apr 4.

Radiological Sciences Division, Mallinckrodt Institute of Radiology, Washington University School of Medicine , 510 South Kingshighway Boulevard, St. Louis, Missouri 63110, United States.

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April 2014

A digital revolution in radiosynthesis.

Authors:

David E Reichert

J Nucl Med 2014 Feb 23;55(2):181-2. Epub 2013 Dec 23.

Washington University School of Medicine St. Louis, Missouri.

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February 2014

Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands.

Authors:

Aixiao Li Yogesh Mishra Maninder Malik Qi Wang Shihong Li Michelle Taylor David E Reichert Robert R Luedtke Robert H Mach

Bioorg Med Chem 2013 Jun 6;21(11):2988-98. Epub 2013 Apr 6.

Department of Radiology, Division of Radiological Sciences, Washington University School of Medicine, Mallinckrodt Institute of Radiology, St. Louis, MO 63110, USA.

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June 2013

Comparison of the binding and functional properties of two structurally different D2 dopamine receptor subtype selective compounds.

Authors:

Robert R Luedtke Yogesh Mishra Qi Wang Suzy A Griffin Cathy Bell-Horner Michelle Taylor Suwanna Vangveravong Glenn H Dillon Ren-Qi Huang David E Reichert Robert H Mach

ACS Chem Neurosci 2012 Dec 12;3(12):1050-62. Epub 2012 Oct 12.

The Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA.

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December 2012

Microfluidic radiolabeling of biomolecules with PET radiometals.

Authors:

Dexing Zeng Amit V Desai David Ranganathan Tobias D Wheeler Paul J A Kenis David E Reichert

Nucl Med Biol 2013 Jan 15;40(1):42-51. Epub 2012 Oct 15.

Radiological Sciences Division, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Blvd., St. Louis, MO 63110, USA.

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January 2013