Publications by authors named "David E Reichert"

42Publications

Analysis of Modulation of the 1 GABA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites.

Mol Pharmacol 2020 10 16;98(4):280-291. Epub 2020 Jul 16.

Departments of Anesthesiology (A.L.G., A.B.B., S.R.P., A.S.E., J.H.S., G.A.) and Radiology (D.E.R.) and the Taylor Family Institute for Innovative Psychiatric Research (D.E.R., A.S.E., J.H.S., G.A.), Washington University School of Medicine, St. Louis, Missouri

View Article and Find Full Text PDF
October 2020

The molecular determinants of neurosteroid binding in the GABA(A) receptor.

J Steroid Biochem Mol Biol 2019 09 28;192:105383. Epub 2019 May 28.

Department of Anesthesiology, Washington University in St. Louis, St. Louis, MO 63110, USA. Electronic address:

View Article and Find Full Text PDF
September 2019

Multiple functional neurosteroid binding sites on GABAA receptors.

PLoS Biol 2019 03 7;17(3):e3000157. Epub 2019 Mar 7.

Department of Anesthesiology, Washington University in St Louis, St Louis, Missouri, United States of America.

View Article and Find Full Text PDF
March 2019

"Click Chip" Conjugation of Bifunctional Chelators to Biomolecules.

Bioconjug Chem 2017 04 9;28(4):986-994. Epub 2017 Feb 9.

Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

View Article and Find Full Text PDF
April 2017

A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons.

Sci Rep 2016 12 16;6:38808. Epub 2016 Dec 16.

Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110, USA.

View Article and Find Full Text PDF
December 2016

Microfluidic Preparation of a 89Zr-Labeled Trastuzumab Single-Patient Dose.

J Nucl Med 2016 05 14;57(5):747-52. Epub 2016 Jan 14.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri; and

View Article and Find Full Text PDF
May 2016

Bitropic D3 Dopamine Receptor Selective Compounds as Potential Antipsychotics.

Curr Pharm Des 2015 ;21(26):3700-24

Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, TX, USA.

View Article and Find Full Text PDF
June 2016

Development of a microfluidic "click chip" incorporating an immobilized Cu(I) catalyst.

RSC Adv 2015 Jan;5(8):6142-6150

Radiological Sciences Division, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Blvd., St. Louis, MO 63110, USA.

View Article and Find Full Text PDF
January 2015

Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands.

Bioorg Med Chem Lett 2015 Feb 17;25(3):519-23. Epub 2014 Dec 17.

Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, United States; Department of Cell Biology & Physiology, Washington University School of Medicine, St. Louis, MO 63110, United States; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, United States. Electronic address:

View Article and Find Full Text PDF
February 2015

Thiolene and SIFEL-based Microfluidic Platforms for Liquid-Liquid Extraction.

Sens Actuators B Chem 2014 Jan;190:634-644

Department of Chemical & Biomolecular Engineering, University of Illinois, Urbana-Champaign, Urbana, IL 61801, USA.

View Article and Find Full Text PDF
January 2014

Triazine-based tool box for developing peptidic PET imaging probes: syntheses, microfluidic radiolabeling, and structure-activity evaluation.

Bioconjug Chem 2014 Apr 4;25(4):761-72. Epub 2014 Apr 4.

Radiological Sciences Division, Mallinckrodt Institute of Radiology, Washington University School of Medicine , 510 South Kingshighway Boulevard, St. Louis, Missouri 63110, United States.

View Article and Find Full Text PDF
April 2014

A digital revolution in radiosynthesis.

Authors:
David E Reichert

J Nucl Med 2014 Feb 23;55(2):181-2. Epub 2013 Dec 23.

Washington University School of Medicine St. Louis, Missouri.

View Article and Find Full Text PDF
February 2014

Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands.

Bioorg Med Chem 2013 Jun 6;21(11):2988-98. Epub 2013 Apr 6.

Department of Radiology, Division of Radiological Sciences, Washington University School of Medicine, Mallinckrodt Institute of Radiology, St. Louis, MO 63110, USA.

View Article and Find Full Text PDF
June 2013

Comparison of the binding and functional properties of two structurally different D2 dopamine receptor subtype selective compounds.

ACS Chem Neurosci 2012 Dec 12;3(12):1050-62. Epub 2012 Oct 12.

The Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA.

View Article and Find Full Text PDF
December 2012

Microfluidic radiolabeling of biomolecules with PET radiometals.

Nucl Med Biol 2013 Jan 15;40(1):42-51. Epub 2012 Oct 15.

Radiological Sciences Division, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Blvd., St. Louis, MO 63110, USA.

View Article and Find Full Text PDF
January 2013

Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor.

Mol Pharmacol 2012 Sep 30;82(3):408-19. Epub 2012 May 30.

Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

View Article and Find Full Text PDF
September 2012