David E Larson

David E Larson

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David E Larson

David E Larson

Publications by authors named "David E Larson"

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52Publications

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svtools: population-scale analysis of structural variation.

Bioinformatics 2019 Jun 20. Epub 2019 Jun 20.

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz492DOI Listing
June 2019

Comprehensive discovery of noncoding RNAs in acute myeloid leukemia cell transcriptomes.

Exp Hematol 2017 11 28;55:19-33. Epub 2017 Jul 28.

The McDonnell Genome Institute, Washington University, St. Louis, MO; Department of Medicine, Washington University, St. Louis, MO; Siteman Cancer Center, Washington University, St. Louis, MO; Department of Biomedical Engineering, Washington University, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772960PMC
November 2017

Rare Variation in TET2 Is Associated with Clinically Relevant Prostate Carcinoma in African Americans.

Cancer Epidemiol Biomarkers Prev 2016 11 2;25(11):1456-1463. Epub 2016 Aug 2.

Division of Urology, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093030PMC
November 2016

Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas.

Cell Rep 2016 09;17(1):249-260

McDonnell Genome Institute, Washington University School of Medicine, 4444 Forest Park Ave., St. Louis, MO 63108, USA; Department of Medicine, Washington University School of Medicine, 660 S Euclid Ave., St. Louis, MO 63110, USA; Siteman Cancer Center, Washington University School of Medicine, 4921 Parkview Pl., St. Louis, MO 63110, USA; Department of Genetics, Washington University School of Medicine, 660 S Euclid Ave., St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.08.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557050PMC
September 2016

Using SomaticSniper to Detect Somatic Single Nucleotide Variants.

Curr Protoc Bioinformatics 2014 ;45:15.5.1-8

The Genome Institute at Washington University, St. Louis, Missouri.

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http://dx.doi.org/10.1002/0471250953.bi1505s45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242521PMC
July 2016

Integrated analysis of germline and somatic variants in ovarian cancer.

Nat Commun 2014 ;5:3156

1] The Genome Institute, Washington University, St. Louis, Missouri 63108, USA [2] Department of Genetics, Washington University, St. Louis, Missouri 63108, USA [3] Siteman Cancer Center, Washington University, St. Louis, Missouri 63108, USA [4] Department of Medicine, Washington University, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/ncomms4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025965PMC
March 2016

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.

PLoS One 2015 7;10(4):e0122271. Epub 2015 Apr 7.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122271PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388675PMC
March 2016

Optimizing cancer genome sequencing and analysis.

Cell Syst 2015 Sep;1(3):210-223

The McDonnell Genome Institute, Washington University, St. Louis, MO, USA, 63108 ; Department of Genetics, Washington University, St. Louis, MO, USA, 63108 ; Siteman Cancer Center, Washington University, St. Louis, MO, USA, 63108 ; Department of Medicine, Washington University, St. Louis, MO, USA, 63108.

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http://dx.doi.org/10.1016/j.cels.2015.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669575PMC
September 2015

Genome Modeling System: A Knowledge Management Platform for Genomics.

PLoS Comput Biol 2015 Jul 9;11(7):e1004274. Epub 2015 Jul 9.

The Genome Institute, Washington University in St. Louis, St. Louis, Missouri, United States of America; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America; Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497734PMC
July 2015

DGIdb: mining the druggable genome.

Nat Methods 2013 Dec 13;10(12):1209-10. Epub 2013 Oct 13.

1] The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA. [3].

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http://dx.doi.org/10.1038/nmeth.2689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851581PMC
December 2013

Using VarScan 2 for Germline Variant Calling and Somatic Mutation Detection.

Curr Protoc Bioinformatics 2013 Dec;44:15.4.1-17

The Genome Institute at Washington University in St. Louis, Missouri, USA, 63108.

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http://dx.doi.org/10.1002/0471250953.bi1504s44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278659PMC
December 2013

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.

N Engl J Med 2013 05 1;368(22):2059-74. Epub 2013 May 1.

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http://dx.doi.org/10.1056/NEJMoa1301689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767041PMC
May 2013

Massively parallel sequencing approaches for characterization of structural variation.

Methods Mol Biol 2012 ;838:369-84

The Genome Institute at Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1007/978-1-61779-507-7_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679911PMC
April 2012

Computer simulation of cellular patterning within the Drosophila pupal eye.

PLoS Comput Biol 2010 Jul 1;6:e1000841. Epub 2010 Jul 1.

The Genome Center at Washington University, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1000841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895643PMC
July 2010

VarScan: variant detection in massively parallel sequencing of individual and pooled samples.

Bioinformatics 2009 Sep 19;25(17):2283-5. Epub 2009 Jun 19.

The Genome Center at Washington University School of Medicine, St Louis, MO 63108, USA.

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http://dx.doi.org/10.1093/bioinformatics/btp373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734323PMC
September 2009

Somatic mutations affect key pathways in lung adenocarcinoma.

Nature 2008 Oct;455(7216):1069-75

The Genome Center at Washington University, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature07423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694412PMC
October 2008

Cellular behavior in the developing Drosophila pupal retina.

Mech Dev 2008 Mar-Apr;125(3-4):223-32. Epub 2007 Nov 24.

Department of Molecular Biology and Pharmacology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8103, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.mod.2007.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965056PMC
April 2008

Dynamic decapentaplegic signaling regulates patterning and adhesion in the Drosophila pupal retina.

Development 2007 May 11;134(10):1861-71. Epub 2007 Apr 11.

Department of Molecular Biology and Pharmacology, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1242/dev.002972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957290PMC
May 2007

Dissection of functional domains of the polar localization factor PodJ in Caulobacter crescentus.

Mol Microbiol 2006 Jan;59(1):301-16

Department of Biology, Indiana University, 1001 E. Third Street, Bloomington, IN 47405-7005, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2005.04935.xDOI Listing
January 2006

Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis.

Dev Cell 2006 Jan;10(1):33-44

Department of Molecular Biology and Pharmacology, Washington University School of Medicine, 660 South Euclid Avenue, Saint Louis, Missouri 63110, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153458070500430
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http://dx.doi.org/10.1016/j.devcel.2005.11.007DOI Listing
January 2006

Identification of genes required for synthesis of the adhesive holdfast in Caulobacter crescentus.

J Bacteriol 2003 Feb;185(4):1432-42

Department of Biology, Indiana University, Bloomington, Indiana 47405, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC142846PMC
http://dx.doi.org/10.1128/jb.185.4.1432-1442.2003DOI Listing
February 2003

The Caulobacter crescentus polar organelle development protein PodJ is differentially localized and is required for polar targeting of the PleC development regulator.

Mol Microbiol 2003 Feb;47(4):929-41

Department of Biology, Jordan Hall 142, Indiana University, Bloomington, IN 47405-3700, USA.

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http://dx.doi.org/10.1046/j.1365-2958.2003.03349.xDOI Listing
February 2003