David D L Bowtell

David D L Bowtell

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David D L Bowtell

Publications by authors named "David D L Bowtell"

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Mechanisms of Drug Resistance in High-Grade Serous Ovarian Cancer.

Hematol Oncol Clin North Am 2018 12;32(6):983-996

Cancer Research Division, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Victoria 3000, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.hoc.2018.07.007DOI Listing
December 2018

Response rates to second-line platinum-based therapy in ovarian cancer patients challenge the clinical definition of platinum resistance.

Gynecol Oncol 2018 08 26;150(2):239-246. Epub 2018 May 26.

Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia; The University of Sydney, Sydney, New South Wales, Australia; Department of Gynaecological Oncology, Westmead Hospital, Westmead, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2018.05.020DOI Listing
August 2018

Mechanisms and clinical implications of tumor heterogeneity and convergence on recurrent phenotypes.

J Mol Med (Berl) 2017 11 4;95(11):1167-1178. Epub 2017 Sep 4.

Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1007/s00109-017-1587-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296823PMC
November 2017

Reversion of BRCA1/2 Germline Mutations Detected in Circulating Tumor DNA From Patients With High-Grade Serous Ovarian Cancer.

J Clin Oncol 2017 Apr 13;35(12):1274-1280. Epub 2017 Feb 13.

Elizabeth L. Christie, Sian Fereday, Ken Doig, Sarah-Jane Dawson, and David D.L. Bowtell, Peter MacCallum Cancer Centre, Melbourne; Elizabeth L. Christe, Ken Doig, Sarah-Jane Dawson, David D.L. Bowtell, University of Melbourne, Melbourne, Victoria; and Swetansu Pattnaik and David D.L. Bowtell, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1200/JCO.2016.70.4627DOI Listing
April 2017

A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers.

Cancer Res 2017 02 6;77(4):971-981. Epub 2016 Dec 6.

Children's Cancer Institute Australia, Lowy Cancer Research Centre, University of New South Wales Australia, Kensington, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2906DOI Listing
February 2017

Long-term survival of patients with mismatch repair protein-deficient, high-stage ovarian clear cell carcinoma.

Histopathology 2017 Jan 21;70(2):309-313. Epub 2016 Sep 21.

School for Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1111/his.13040DOI Listing
January 2017

Commentary on "Epithelial-to-Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer".

Cancer Res 2016 12;76(24):7075-7077

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-3022DOI Listing
December 2016

Blood Worth Bottling: Circulating Tumor DNA as a Cancer Biomarker.

Cancer Res 2016 10;76(19):5590-5591

Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia. Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia. The Kinghorn Cancer Centre, Garvan Institute for Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2281DOI Listing
October 2016

Serous ovarian and primary peritoneal cancers: A comparative analysis of clinico-pathological features, molecular subtypes and treatment outcome.

Gynecol Oncol 2016 Sep 18;142(3):458-64. Epub 2016 Jul 18.

The Westmead Institute for Medical Research, The University of Sydney, Sydney, NSW, Australia; Department of Gynecological Oncology, Westmead Hospital, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.06.023DOI Listing
September 2016

Loss of heterozygosity: what is it good for?

BMC Med Genomics 2015 Aug 1;8:45. Epub 2015 Aug 1.

Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1186/s12920-015-0123-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522148PMC
August 2015

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors.

Genome Med 2015 7;7(1):87. Epub 2015 Aug 7.

Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria Australia ; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria Australia ; Department of Pathology, University of Melbourne, Parkville, Victoria Australia.

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http://dx.doi.org/10.1186/s13073-015-0210-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528310PMC
August 2015

Enhanced GAB2 Expression Is Associated with Improved Survival in High-Grade Serous Ovarian Cancer and Sensitivity to PI3K Inhibition.

Mol Cancer Ther 2015 Jun 7;14(6):1495-503. Epub 2015 Apr 7.

Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia. Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia. Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0039DOI Listing
June 2015

Whole-genome characterization of chemoresistant ovarian cancer.

Nature 2015 May;521(7553):489-94

1] Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia [2] Department of Pathology, University of Melbourne, Parkville, Victoria 3052, Australia [3] Sir Peter MacCallum Cancer Centre Department of Oncology, University of Melbourne, Parkville, Victoria 3052, Australia [4] Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London W12 0HS, UK [5] Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1038/nature14410DOI Listing
May 2015

Genomic classification of serous ovarian cancer with adjacent borderline differentiates RAS pathway and TP53-mutant tumors and identifies NRAS as an oncogenic driver.

Clin Cancer Res 2014 Dec 14;20(24):6618-30. Epub 2014 Oct 14.

Department of Gynaecological Oncology, Westmead Hospital, Sydney, New South Wales, Australia. Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, New South Wales, Australia. University of Sydney, Westmead Hospital, Sydney, New South Wales, Australia. Westmead Institute for Cancer Research, Westmead Millennium Institute, Westmead Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1292DOI Listing
December 2014

Identifying associations between genomic alterations in tumors.

Methods Mol Biol 2013 ;1049:9-19

Cancer Genetics and Genomics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/978-1-62703-547-7_2DOI Listing
March 2014

Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube-derived high-grade serous ovarian cancers.

Cancer Res 2014 Feb 23;74(4):1141-52. Epub 2013 Dec 23.

Authors' Affiliations: Department of Medical Oncology; Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute; Harvard Medical School; Department of Pathology, Division of Cytogenetics; Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts; Peter MacCallum Cancer Centre, East Melbourne; Department of Oncology, Peter MacCallum Cancer Centre; Departments of Pathology and Biochemistry and Molecular Biology, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517944PMC
February 2014

Synthetic lethality between CCNE1 amplification and loss of BRCA1.

Proc Natl Acad Sci U S A 2013 Nov 11;110(48):19489-94. Epub 2013 Nov 11.

Department of Research, Peter MacCallum Cancer Centre, East Melbourne, VIC 3002, Australia.

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http://dx.doi.org/10.1073/pnas.1314302110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845173PMC
November 2013

RNF43 is a tumour suppressor gene mutated in mucinous tumours of the ovary.

J Pathol 2013 Feb;229(3):469-76

Victorian Breast Cancer Research Consortium (VBCRC), Cancer Genetics Laboratory, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/path.4134DOI Listing
February 2013

The genesis and evolution of high-grade serous ovarian cancer.

Nat Rev Cancer 2010 11 14;10(11):803-8. Epub 2010 Oct 14.

Peter MacCallum Cancer Centre, Department of Biochemistry, University of Melbourne, Melbourne 3002, Australia.

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http://dx.doi.org/10.1038/nrc2946DOI Listing
November 2010

Profiling the cancer genome.

Annu Rev Genomics Hum Genet 2010 ;11:133-59

Peter MacCallum Cancer Center, East Melbourne, Australia 3002.

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http://dx.doi.org/10.1146/annurev-genom-082509-141536DOI Listing
September 2010

International network of cancer genome projects.

Authors:
Thomas J Hudson Warwick Anderson Axel Artez Anna D Barker Cindy Bell Rosa R Bernabé M K Bhan Fabien Calvo Iiro Eerola Daniela S Gerhard Alan Guttmacher Mark Guyer Fiona M Hemsley Jennifer L Jennings David Kerr Peter Klatt Patrik Kolar Jun Kusada David P Lane Frank Laplace Lu Youyong Gerd Nettekoven Brad Ozenberger Jane Peterson T S Rao Jacques Remacle Alan J Schafer Tatsuhiro Shibata Michael R Stratton Joseph G Vockley Koichi Watanabe Huanming Yang Matthew M F Yuen Bartha M Knoppers Martin Bobrow Anne Cambon-Thomsen Lynn G Dressler Stephanie O M Dyke Yann Joly Kazuto Kato Karen L Kennedy Pilar Nicolás Michael J Parker Emmanuelle Rial-Sebbag Carlos M Romeo-Casabona Kenna M Shaw Susan Wallace Georgia L Wiesner Nikolajs Zeps Peter Lichter Andrew V Biankin Christian Chabannon Lynda Chin Bruno Clément Enrique de Alava Françoise Degos Martin L Ferguson Peter Geary D Neil Hayes Thomas J Hudson Amber L Johns Arek Kasprzyk Hidewaki Nakagawa Robert Penny Miguel A Piris Rajiv Sarin Aldo Scarpa Tatsuhiro Shibata Marc van de Vijver P Andrew Futreal Hiroyuki Aburatani Mónica Bayés David D L Botwell Peter J Campbell Xavier Estivill Daniela S Gerhard Sean M Grimmond Ivo Gut Martin Hirst Carlos López-Otín Partha Majumder Marco Marra John D McPherson Hidewaki Nakagawa Zemin Ning Xose S Puente Yijun Ruan Tatsuhiro Shibata Michael R Stratton Hendrik G Stunnenberg Harold Swerdlow Victor E Velculescu Richard K Wilson Hong H Xue Liu Yang Paul T Spellman Gary D Bader Paul C Boutros Peter J Campbell Paul Flicek Gad Getz Roderic Guigó Guangwu Guo David Haussler Simon Heath Tim J Hubbard Tao Jiang Steven M Jones Qibin Li Nuria López-Bigas Ruibang Luo Lakshmi Muthuswamy B F Francis Ouellette John V Pearson Xose S Puente Victor Quesada Benjamin J Raphael Chris Sander Tatsuhiro Shibata Terence P Speed Lincoln D Stein Joshua M Stuart Jon W Teague Yasushi Totoki Tatsuhiko Tsunoda Alfonso Valencia David A Wheeler Honglong Wu Shancen Zhao Guangyu Zhou Lincoln D Stein Roderic Guigó Tim J Hubbard Yann Joly Steven M Jones Arek Kasprzyk Mark Lathrop Nuria López-Bigas B F Francis Ouellette Paul T Spellman Jon W Teague Gilles Thomas Alfonso Valencia Teruhiko Yoshida Karen L Kennedy Myles Axton Stephanie O M Dyke P Andrew Futreal Daniela S Gerhard Chris Gunter Mark Guyer Thomas J Hudson John D McPherson Linda J Miller Brad Ozenberger Kenna M Shaw Arek Kasprzyk Lincoln D Stein Junjun Zhang Syed A Haider Jianxin Wang Christina K Yung Anthony Cros Anthony Cross Yong Liang Saravanamuttu Gnaneshan Jonathan Guberman Jack Hsu Martin Bobrow Don R C Chalmers Karl W Hasel Yann Joly Terry S H Kaan Karen L Kennedy Bartha M Knoppers William W Lowrance Tohru Masui Pilar Nicolás Emmanuelle Rial-Sebbag Laura Lyman Rodriguez Catherine Vergely Teruhiko Yoshida Sean M Grimmond Andrew V Biankin David D L Bowtell Nicole Cloonan Anna deFazio James R Eshleman Dariush Etemadmoghadam Brooke B Gardiner Brooke A Gardiner James G Kench Aldo Scarpa Robert L Sutherland Margaret A Tempero Nicola J Waddell Peter J Wilson John D McPherson Steve Gallinger Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Debabrata Mukhopadhyay Lynda Chin Ronald A DePinho Sarah Thayer Lakshmi Muthuswamy Kamran Shazand Timothy Beck Michelle Sam Lee Timms Vanessa Ballin Youyong Lu Jiafu Ji Xiuqing Zhang Feng Chen Xueda Hu Guangyu Zhou Qi Yang Geng Tian Lianhai Zhang Xiaofang Xing Xianghong Li Zhenggang Zhu Yingyan Yu Jun Yu Huanming Yang Mark Lathrop Jörg Tost Paul Brennan Ivana Holcatova David Zaridze Alvis Brazma Lars Egevard Egor Prokhortchouk Rosamonde Elizabeth Banks Mathias Uhlén Anne Cambon-Thomsen Juris Viksna Fredrik Ponten Konstantin Skryabin Michael R Stratton P Andrew Futreal Ewan Birney Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Sancha Martin Jorge S Reis-Filho Andrea L Richardson Christos Sotiriou Hendrik G Stunnenberg Giles Thoms Marc van de Vijver Laura van't Veer Fabien Calvo Daniel Birnbaum Hélène Blanche Pascal Boucher Sandrine Boyault Christian Chabannon Ivo Gut Jocelyne D Masson-Jacquemier Mark Lathrop Iris Pauporté Xavier Pivot Anne Vincent-Salomon Eric Tabone Charles Theillet Gilles Thomas Jörg Tost Isabelle Treilleux Fabien Calvo Paulette Bioulac-Sage Bruno Clément Thomas Decaens Françoise Degos Dominique Franco Ivo Gut Marta Gut Simon Heath Mark Lathrop Didier Samuel Gilles Thomas Jessica Zucman-Rossi Peter Lichter Roland Eils Benedikt Brors Jan O Korbel Andrey Korshunov Pablo Landgraf Hans Lehrach Stefan Pfister Bernhard Radlwimmer Guido Reifenberger Michael D Taylor Christof von Kalle Partha P Majumder Rajiv Sarin T S Rao M K Bhan Aldo Scarpa Paolo Pederzoli Rita A Lawlor Massimo Delledonne Alberto Bardelli Andrew V Biankin Sean M Grimmond Thomas Gress David Klimstra Giuseppe Zamboni Tatsuhiro Shibata Yusuke Nakamura Hidewaki Nakagawa Jun Kusada Tatsuhiko Tsunoda Satoru Miyano Hiroyuki Aburatani Kazuto Kato Akihiro Fujimoto Teruhiko Yoshida Elias Campo Carlos López-Otín Xavier Estivill Roderic Guigó Silvia de Sanjosé Miguel A Piris Emili Montserrat Marcos González-Díaz Xose S Puente Pedro Jares Alfonso Valencia Heinz Himmelbauer Heinz Himmelbaue Victor Quesada Silvia Bea Michael R Stratton P Andrew Futreal Peter J Campbell Anne Vincent-Salomon Andrea L Richardson Jorge S Reis-Filho Marc van de Vijver Gilles Thomas Jocelyne D Masson-Jacquemier Samuel Aparicio Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Hendrik G Stunnenberg Laura van't Veer Douglas F Easton Paul T Spellman Sancha Martin Anna D Barker Lynda Chin Francis S Collins Carolyn C Compton Martin L Ferguson Daniela S Gerhard Gad Getz Chris Gunter Alan Guttmacher Mark Guyer D Neil Hayes Eric S Lander Brad Ozenberger Robert Penny Jane Peterson Chris Sander Kenna M Shaw Terence P Speed Paul T Spellman Joseph G Vockley David A Wheeler Richard K Wilson Thomas J Hudson Lynda Chin Bartha M Knoppers Eric S Lander Peter Lichter Lincoln D Stein Michael R Stratton Warwick Anderson Anna D Barker Cindy Bell Martin Bobrow Wylie Burke Francis S Collins Carolyn C Compton Ronald A DePinho Douglas F Easton P Andrew Futreal Daniela S Gerhard Anthony R Green Mark Guyer Stanley R Hamilton Tim J Hubbard Olli P Kallioniemi Karen L Kennedy Timothy J Ley Edison T Liu Youyong Lu Partha Majumder Marco Marra Brad Ozenberger Jane Peterson Alan J Schafer Paul T Spellman Hendrik G Stunnenberg Brandon J Wainwright Richard K Wilson Huanming Yang

Nature 2010 Apr;464(7291):993-8

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http://dx.doi.org/10.1038/nature08987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902243PMC
April 2010

Siah proteins: novel drug targets in the Ras and hypoxia pathways.

Cancer Res 2009 Dec 17;69(23):8835-8. Epub 2009 Nov 17.

Cancer Genomics and Genetics Laboratory, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1676DOI Listing
December 2009

An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response.

Nat Cell Biol 2009 Jan 30;11(1):85-91. Epub 2008 Nov 30.

Institute of Biochemistry, Medical Faculty, Friedrichstrasse 24, Justus-Liebig-University, D-35392 Giessen, Germany.

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http://search.proquest.com/openview/4b600c3b291816a0c9fb952e
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http://dx.doi.org/10.1038/ncb1816DOI Listing
January 2009

Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.

J Biol Chem 2008 Jan 12;283(2):1034-42. Epub 2007 Nov 12.

Department of Life Science, Division of Molecular and Life Science, Pohang University of Science and Technology, Pohang, Kyung-Buk 790-784, Republic of Korea.

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http://dx.doi.org/10.1074/jbc.M705874200DOI Listing
January 2008

Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis.

BMC Bioinformatics 2006 Nov 22;7:511. Epub 2006 Nov 22.

Ian Potter Foundation Centre for Cancer Genomics and Predictive Medicine, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, Victoria 3002, Australia.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-7-511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664592PMC
November 2006

A molecular diagnostic test for distinguishing lung adenocarcinoma from malignant mesothelioma using cells collected from pleural effusions.

Clin Cancer Res 2006 Sep;12(17):5129-35

Ian Potter Centre for Cancer Genomics and Predictive Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-06-1027DOI Listing
September 2006

The challenges of gene expression microarrays for the study of human cancer.

Cancer Cell 2006 May;9(5):333-9

Ian Potter Centre for Cancer Genomics and Predictive Medicine, Peter MacCallum Cancer Centre, St. Andrew's Place, East Melbourne 3002, Victoria, Australia.

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http://dx.doi.org/10.1016/j.ccr.2006.05.001DOI Listing
May 2006

Elucidation of the substrate binding site of Siah ubiquitin ligase.

Structure 2006 Apr;14(4):695-701

Ian Potter Foundation Centre for Cancer Genomics and Predictive Medicine, Peter MacCallum Cancer Centre, Locked Bag 1 A'Beckett Street, Melbourne, Victoria 8006, Australia.

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http://dx.doi.org/10.1016/j.str.2005.12.013DOI Listing
April 2006

Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization.

Genes Chromosomes Cancer 2005 Mar;42(3):247-59

Trescowthick Research Laboratories, Peter MacCallum Cancer Centre, Melbourne, Australia.

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http://dx.doi.org/10.1002/gcc.20136DOI Listing
March 2005

Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah.

J Biol Chem 2004 Dec 5;279(51):53782-8. Epub 2004 Oct 5.

Department of Oncological Sciences, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1074/jbc.M410315200DOI Listing
December 2004

Osteopenia in Siah1a mutant mice.

J Biol Chem 2004 Jul 3;279(28):29583-8. Epub 2004 May 3.

Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, East Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.1074/jbc.M312755200DOI Listing
July 2004

Drosophila Hfp negatively regulates dmyc and stg to inhibit cell proliferation.

Development 2004 Mar;131(6):1411-23

Trescowthick Research Laboratories, Peter MacCallum Cancer Centre, St Andrew's Place, East Melbourne, VIC 3002 Australia.

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http://dx.doi.org/10.1242/dev.01019DOI Listing
March 2004

Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement.

J Cell Physiol 2003 May;195(2):276-89

Department of Pathology, Section of General Pathology, University of Verona, Verona, Italy.

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http://dx.doi.org/10.1002/jcp.10236DOI Listing
May 2003

Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer.

Cancer Res 2003 May;63(10):2569-77

Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Melbourne, Victoria, 8006, Australia.

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http://cancerres.aacrjournals.org/content/63/10/2569.full.pd
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May 2003

A binding motif for Siah ubiquitin ligase.

Proc Natl Acad Sci U S A 2003 Mar 7;100(6):3101-6. Epub 2003 Mar 7.

Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Melbourne 8006, Victoria, Australia.

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http://dx.doi.org/10.1073/pnas.0534783100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152253PMC
March 2003

Normal p53 function in primary cells deficient for Siah genes.

Mol Cell Biol 2002 Dec;22(23):8155-64

Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, East Melbourne, Victoria 3002, Australia.

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http://mcb.asm.org/content/22/23/8155.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134066PMC
http://dx.doi.org/10.1128/mcb.22.23.8155-8164.2002DOI Listing
December 2002

Options available--from start to finish--for obtaining data from DNA microarrays II.

Nat Genet 2002 Dec;32 Suppl:481-9

The Ian Potter Foundation Centre for Cancer Genomics and Predictive Medicine and The Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett Street, Melbourne 8006, Victoria, Australia.

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http://dx.doi.org/10.1038/ng1030DOI Listing
December 2002

Stress-induced decrease in TRAF2 stability is mediated by Siah2.

EMBO J 2002 Nov;21(21):5756-65

Ruttenberg Cancer Center and Department of Biochemistry and Molecular Biology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC131073PMC
http://dx.doi.org/10.1093/emboj/cdf576DOI Listing
November 2002

Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.

Nat Struct Biol 2002 Jan;9(1):68-75

Biota Structural Biology Laboratory, St. Vincent's Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia.

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http://www.nature.com/doifinder/10.1038/nsb743
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http://dx.doi.org/10.1038/nsb743DOI Listing
January 2002