David Craufurd

David Craufurd

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David Craufurd

Publications by authors named "David Craufurd"

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Insensitivity to loss predicts apathy in huntington's disease.

Mov Disord 2019 09 30;34(9):1381-1391. Epub 2019 Jul 30.

Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1002/mds.27787DOI Listing
September 2019

Targeting Huntingtin Expression in Patients with Huntington's Disease.

N Engl J Med 2019 06 6;380(24):2307-2316. Epub 2019 May 6.

From University College London (UCL) Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, UCL, and the U.K. Dementia Research Institute at UCL, London (S.J.T., E.J.W.), the Department of Clinical Neuroscience, Addenbrooke's Hospital, University of Cambridge, Cambridge (R.A.B., N.F.B.), Manchester Centre for Genomic Medicine, St. Mary's Hospital, Manchester University NHS Foundation Trust, and the Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester (D.C.), the University of Edinburgh and the U.K. Dementia Research Institute, Edinburgh (J.P.), the Institute of Clinical Sciences, College of Medical and Dental Sciences, University Hospital Birmingham, Birmingham (H.R.), and the Cardiff University Brain Repair Group, Brain Repair and Intracranial Neurotherapeutics Unit, Neuroscience and Mental Health Research Institute and School of Biosciences, Cardiff (A.R.) - all in the United Kingdom; the Centre for Huntington's Disease, Department of Medical Genetics, and the Division of Neurology, Department of Medicine, University of British Columbia, and the Centre for Molecular Medicine and Therapeutics, B.C. Children's Hospital, Vancouver, Canada (B.R.L.); the Department of Neurology, Ulm University, Huntington's Disease Centre, Ulm (G.B.L.), the Department of Neurology, Huntington Center North Rhine-Westphalia, Ruhr University Bochum, St. Josef-Hospital, Bochum (C.S.), and the Department of Neuropsychiatry, Charité-Universitätsmedizin Berlin, Deutsches Zentrum für Neurodegenerative Erkrankungen, Berlin (J.P.) - all in Germany; Ionis Pharmaceuticals, Carlsbad, CA (H.B.K., E.E.S., D.A.N., T.B., E.P., A.V.S., C.F.B., R.M.L.); and F. Hoffmann-La Roche, Basel, Switzerland (C.C., I.G., S.A.S.).

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http://dx.doi.org/10.1056/NEJMoa1900907DOI Listing
June 2019

Apathy Associated With Impaired Recognition of Happy Facial Expressions in Huntington's Disease.

J Int Neuropsychol Soc 2019 May 15;25(5):453-461. Epub 2019 Feb 15.

2Monash Institute of Cognitive and Clinical Neurosciences,School of Psychological Sciences,Monash University,Melbourne,Australia.

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http://dx.doi.org/10.1017/S1355617718001224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542690PMC
May 2019

Obsessive-Compulsive and Perseverative Behaviors in Huntington's Disease.

J Huntingtons Dis 2019 ;8(1):1-7

Department of Psychiatry, Leiden University Medical Centre, Leiden; and Centre for Mental Health Care Delfland, Delft, The Netherlands.

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http://dx.doi.org/10.3233/JHD-180335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398547PMC
January 2019

Executive impairment is associated with unawareness of neuropsychiatric symptoms in premanifest and early Huntington's disease.

Neuropsychology 2018 Nov 13;32(8):958-965. Epub 2018 Sep 13.

Monash Institute of Cognitive and Clinical Neurosciences, School of Psychological Sciences, Monash University.

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http://dx.doi.org/10.1037/neu0000479DOI Listing
November 2018

Exploring the Validity of the Short Version of the Problem Behaviours Assessment (PBA-s) for Huntington's disease: A Rasch Analysis.

J Huntingtons Dis 2015 ;4(4):347-69

Faculty of Medicine and Human Sciences, Institute of Human Development, University of Manchester and Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.3233/JHD-150164DOI Listing
October 2016

Neuropsychiatry and White Matter Microstructure in Huntington's Disease.

J Huntingtons Dis 2015 ;4(3):239-49

Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester and Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.3233/JHD-150160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684097PMC
July 2016

Longitudinal Psychiatric Symptoms in Prodromal Huntington's Disease: A Decade of Data.

Am J Psychiatry 2016 Feb 16;173(2):184-92. Epub 2015 Oct 16.

From the Departments of Psychiatry and Neurology, Carver College of Medicine, University of Iowa, Iowa City; the Department of Biostatistics, College of Public Health, University of Iowa, Iowa City; the Department of Psychology, University of Iowa, Iowa City; the Institute of Human Development, University of Manchester, Manchester, U.K.; the Huntington Disease Care, Education, and Research Center and the Departments of Psychiatry and Neurology, MedStar Georgetown University Hospital, Washington, D.C.; and the Department of Neurology, Westmead Hospital, University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1176/appi.ajp.2015.14121551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465431PMC
February 2016

Reliability and factor structure of the Short Problem Behaviors Assessment for Huntington's disease (PBA-s) in the TRACK-HD and REGISTRY studies.

J Neuropsychiatry Clin Neurosci 2015 ;27(1):59-64

From the Cardiff University, School of Biosciences, Cardiff, United Kingdom (JC). Institute of Human Development, Faculty of Medicine and Human Sciences, University of Manchester and Manchester Academic Health Science Centre, Manchester, United Kingdom (CS, NA, DC); Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom (CS, DC); Dept. of Neuropsychology, Salford Royal Hospital NHS Foundation Trust, Salford, United Kingdom (NA); Centre de Référence National pour la Maladie de Huntington, AP-HP, Groupe Henri Mondor-Albert Chenevier, Créteil, France (M-FB, A-CB-L, CB); University of British Columbia, The Centre for Huntington's disease, Vancouver, Canada (AC, RDS); Leiden University Medical Centre, Department of Neurology, Leiden, The Netherlands (EMD, EPH, RACR); UPMC UnivParis06, UMR_S975 and Inserm, UMR_S975, CRICM and CNRS UMR7225, F-75013, Paris, France (DJ, AD); University College London, Institute of Neurology, London, United Kingdom (GO, JR, MJS, SJT); Brain and Spine Institute (ICM), F-75013, Paris, France (AD); AP-HP Pitie-Salpetriere Hospital, Dept. of Genetics and Cytogenetics, F-75013, Paris, France (AD); University of British Columbia, Centre for Molecular Medicine and Therapeutics, Vancouver, Canada (BRL); Service de Psychiatrie, 93G18, EPSVE, 93330 Neuilly-sur-Marne, France (CB); and Dept. of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands (EvD).

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http://dx.doi.org/10.1176/appi.neuropsych.13070169DOI Listing
November 2015

Ethyl-eicosapentaenoic acid treatment in Huntington's disease: A placebo-controlled clinical trial.

Mov Disord 2015 Sep 14;30(10):1426-9. Epub 2015 Jul 14.

Universitätsklinik Ulm, Ulm, Germany.

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http://dx.doi.org/10.1002/mds.26308DOI Listing
September 2015

Diagnostic genetic testing for Huntington's disease.

Pract Neurol 2015 Feb 28;15(1):80-4. Epub 2014 Aug 28.

Department of Neurology, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.

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http://dx.doi.org/10.1136/practneurol-2013-000790DOI Listing
February 2015

Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY).

J Neurol Neurosurg Psychiatry 2014 Dec 14;85(12):1411-8. Epub 2014 May 14.

Department of Neurology, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1136/jnnp-2013-307343DOI Listing
December 2014

Quality of life in Huntington's disease: a comparative study investigating the impact for those with pre-manifest and early manifest disease, and their partners.

J Huntingtons Dis 2013 ;2(2):159-75

University of Manchester, Manchester Academic Health Sciences Centre and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

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http://dx.doi.org/10.3233/JHD-130051DOI Listing
October 2014

Illness perceptions, coping styles and psychological distress in adults with Huntington's disease.

Psychol Health Med 2014 14;19(2):169-79. Epub 2013 Jun 14.

a Department of Neuropsychology , Salford Royal Hospital NHS Foundation Trust , Salford , UK.

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http://dx.doi.org/10.1080/13548506.2013.802355DOI Listing
September 2014

Unawareness of deficits in Huntington's disease.

J Huntingtons Dis 2014 ;3(2):125-35

Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, Salford, UK Institute of Brain, Behaviour and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.3233/JHD-140109DOI Listing
September 2014

Amyotrophic lateral sclerosis and Huntington's disease: neurodegenerative link or coincidence?

Amyotroph Lateral Scler Frontotemporal Degener 2014 Mar 16;15(1-2):145-7. Epub 2013 Jul 16.

Department of Neurology, Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust , Preston, Lancashire.

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http://dx.doi.org/10.3109/21678421.2013.817586DOI Listing
March 2014

The structural correlates of functional deficits in early huntington's disease.

Hum Brain Mapp 2013 Sep 22;34(9):2141-53. Epub 2012 Mar 22.

Center for NeuroImaging Research, Groupe Hospitalier Pitié-Salpêtrière, 47 boulevardde l’Hôpital, Paris Cedex 13, France.

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http://dx.doi.org/10.1002/hbm.22055DOI Listing
September 2013

Better global and cognitive functioning in choreatic versus hypokinetic-rigid Huntington's disease.

Mov Disord 2013 Jul 14;28(8):1142-5. Epub 2013 Mar 14.

Leiden University Medical Centre, Department of Neurology, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/mds.25422DOI Listing
July 2013

Longitudinal evaluation of neuropsychiatric symptoms in Huntington's disease.

J Neuropsychiatry Clin Neurosci 2012 ;24(1):53-60

Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, Salford, UK.

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http://dx.doi.org/10.1176/appi.neuropsych.11030057DOI Listing
August 2012

Treatment of Apathy in Huntington's Disease and Other Movement Disorders.

Curr Treat Options Neurol 2011 Oct;13(5):508-19

Maelor Hospital, Wrexham, LL13 7TD, UK,

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http://dx.doi.org/10.1007/s11940-011-0140-yDOI Listing
October 2011

Assessment of cognitive symptoms in prodromal and early huntington disease.

PLoS Curr 2011 Oct 25;3:RRN1250. Epub 2011 Oct 25.

Research Methods, Ontario Cancer Biomarker Network, Toronto, Ontario, Canada; Department of Psychiatry and Department of Neurology, University of Maryland, School of Medicine, Baltimore, MD USA; Translational Medicine, CHDI Foundation, Inc., Princeton NJ; University of Manchester, Manchester Academic Health Sciences Centre and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK; CHDI Foundation, Inc.; Huntington's Disease Drug Works, Lake Forest Park, WA; Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario Canada; School of Psychology and Clinical Language Sciences, University of Reading, U.K.; Department of Psychiatry, The University of Iowa Carver College of Medicine, Iowa City, IA, USA; School of Psychology and Psychiatry, Monash University, Melbourne, Australia and CNS Drug Development consultant.

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http://dx.doi.org/10.1371/currents.RRN1250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201666PMC
October 2011

An International Survey-based Algorithm for the Pharmacologic Treatment of Obsessive-Compulsive Behaviors in Huntington's Disease.

PLoS Curr 2011 Sep 20;3:RRN1261. Epub 2011 Sep 20.

Department of Psychiatry and Department of Neurology, University of Maryland, School of Medicine, Baltimore, MD USA; University of Manchester, Manchester Academic Health Sciences Centre and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK; Department of Psychiatry, Duke University Medical Center & North Carolina Center for the Care of Huntington's Disease; Institute for Systems Biology, Seattle, WA; Departments of Neurology and Psychiatry, Beth Israel Medical Center, New York, NY; Department of Psychiatry, Leiden University Medical Centre, Leiden; and Centre for Mental Health Care Delfland, Delft, Netherlands; Formerly CHDI Foundation, Inc. Presently independent CNS development consultant and Huntington's Disease Drug Works, Lake Forest Park, WA.

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http://dx.doi.org/10.1371/currents.RRN1261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177175PMC
September 2011

The structural involvement of the cingulate cortex in premanifest and early Huntington's disease.

Mov Disord 2011 Aug 6;26(9):1684-90. Epub 2011 May 6.

Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.23747DOI Listing
August 2011

An International Survey-based Algorithm for the Pharmacologic Treatment of Irritability in Huntington's Disease.

PLoS Curr 2011 Aug 30;3:RRN1259. Epub 2011 Aug 30.

Departments of Neurology and Psychiatry, Beth Israel Medical Center, New York, NY; Department of Psychiatry, Leiden University Medical Centre, Leiden; and Centre for Mental Health Care Delfland, Delft, Netherlands; Department of Psychiatry and Department of Neurology, University of Maryland, School of Medicine, Baltimore, MD USA; University of Manchester, Manchester Academic Health Sciences Centre and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK; Department of Psychiatry, Duke University Medical Center & North Carolina Center for the Care of Huntington's Disease; Institute for Systems Biology; CHDI Foundation, Inc., Princeton, NJ and Huntington's Disease Drug Works.

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http://dx.doi.org/10.1371/currents.RRN1259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166255PMC
August 2011

Assessment of depression, anxiety and apathy in prodromal and early huntington disease.

PLoS Curr 2011 Jun 17;3:RRN1242. Epub 2011 Jun 17.

Research Methods, Ontario Cancer Biomarker Network, Toronto, Ontario, Canada; Department of Psychiatry and Department of Neurology, University of Maryland, School of Medicine, Baltimore, MD USA; AP-HP, centre de référence maladie de Huntington; INSERM U955 E01- Ecole Normale Supérieure-University Paris Est, Neuropsychologie interventionnelle laboratory,Créteil- Paris, France; Translational Medicine, CHDI Foundation, Inc., Princeton NJ; University of Manchester, Manchester Academic Health Sciences Centre and Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK; Neurology, University of Utah, Salt Lake City UT USA; CHDI Foundation, Inc.; Departments of Neurology and Psychiatry, Beth Israel Medical Center, New York, NY; Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario Canada; School of Psychology and Clinical Language Sciences, University of Reading, U.K.; Department of Psychiatry, The University of Iowa Carver College of Medicine, Iowa City, IA, USA; The Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway & Department of Neurology, Stavanger University Hospital, Stavanger, Norway; Department of Psychiatry, Leiden University Medical Centre, Leiden, Netherlands and CNS Drug Development consultant.

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http://dx.doi.org/10.1371/currents.RRN1242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124013PMC
June 2011

Automaticity and attention in Huntington's disease: when two hands are not better than one.

Neuropsychologia 2010 Jan;48(1):171-8

Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, M6 8HD, UK.

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http://dx.doi.org/10.1016/j.neuropsychologia.2009.09.002DOI Listing
January 2010

Irritability in pre-clinical Huntington's disease.

Neuropsychologia 2010 Jan 28;48(2):549-57. Epub 2009 Oct 28.

Department of Psychiatry and Psychotherapy, Freiburg Brain Imaging, University Clinic Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1016/j.neuropsychologia.2009.10.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809920PMC
January 2010

Genetic assessment and management of dementia.

Authors:
David Craufurd

Clin Med (Lond) 2008 Dec;8(6):618-21

University of Manchester.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954401PMC
http://dx.doi.org/10.7861/clinmedicine.8-6-618DOI Listing
December 2008

Psychiatric disorders in preclinical Huntington's disease.

J Neurol Neurosurg Psychiatry 2007 Sep 18;78(9):939-43. Epub 2006 Dec 18.

Cerebral Function Unit, Greater Manchester Neuroscience Centre, Hope Hospital, Salford, UK.

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http://dx.doi.org/10.1136/jnnp.2006.103309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117854PMC
September 2007

Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation.

Acta Neuropathol 2005 Nov 13;110(5):501-12. Epub 2005 Oct 13.

Clinical Neuroscience Research Group, University of Manchester, Greater Manchester Neurosciences Centre, Hope Hospital, Stott Lane, Salford M6 8HD, UK.

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http://dx.doi.org/10.1007/s00401-005-1079-4DOI Listing
November 2005

BRCA1/2 predictive testing: a study of uptake in two centres.

Eur J Hum Genet 2004 Aug;12(8):654-62

Academic Unit of Medical Genetics and Regional Genetics Service, St Mary's Hospital, Manchester M13 0JH, UK.

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http://www.nature.com/articles/5201206
Publisher Site
http://dx.doi.org/10.1038/sj.ejhg.5201206DOI Listing
August 2004

Evidence of a founder effect in families with frontotemporal dementia that harbor the tau +16 splice mutation.

Am J Med Genet B Neuropsychiatr Genet 2004 Feb;125B(1):79-82

Institute of Psychiatry, Section of Old Age Psychiatry, Denmark Hill, London, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.20083DOI Listing
February 2004

Behavior in Huntington's disease: dissociating cognition-based and mood-based changes.

J Neuropsychiatry Clin Neurosci 2002 ;14(1):37-43

Cerebral Function Unit, Greater Manchester Neuroscience Center, Salford, United Kingdom.

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http://dx.doi.org/10.1176/jnp.14.1.37DOI Listing
May 2002

Patients' perceptions of what makes genetic counselling effective: an interpretative phenomenological analysis.

J Health Psychol 2002 Mar;7(2):145-56

St Mary's Hospital, Manchester, UK.

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http://dx.doi.org/10.1177/1359105302007002454DOI Listing
March 2002