Publications by authors named "David C Samuels"

100Publications

Alternative Applications of Genotyping Array Data Using Multivariant Methods.

Trends Genet 2020 Nov 6;36(11):857-867. Epub 2020 Aug 6.

Department of Internal Medicine, Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM 87109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2020.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572808PMC
November 2020

Mitochondria and HIV: A troubled relationship enters its fourth decade.

Clin Infect Dis 2020 Jul 28. Epub 2020 Jul 28.

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1093/cid/ciaa983DOI Listing
July 2020

Non-canonical RNA-DNA differences and other human genomic features are enriched within very short tandem repeats.

PLoS Comput Biol 2020 06 8;16(6):e1007968. Epub 2020 Jun 8.

Comprehensive Cancer Center, University of New Mexico, Albuquerque, New Mexico, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1007968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302867PMC
June 2020

Corrigendum: Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples.

Front Genet 2020;11:162. Epub 2020 Feb 25.

Department of Internal Medicine, The University of New Mexico, Albuquerque, NM, United States.

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http://dx.doi.org/10.3389/fgene.2020.00162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052360PMC
February 2020

Mitochondrial DNA Haplogroups and Frailty in Adults Living with HIV.

AIDS Res Hum Retroviruses 2020 03 14;36(3):214-219. Epub 2020 Jan 14.

Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1089/AID.2019.0233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133433PMC
March 2020

Mitochondrial DNA Haplogroups and Delirium During Sepsis.

Crit Care Med 2019 08;47(8):1065-1071

Clinical Research, Investigation, and Systems Modeling of Acute illness (CRISMA) Center in the Department of Critical Care Medicine, University of Pittsburgh School of Medicine.

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http://dx.doi.org/10.1097/CCM.0000000000003810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012366PMC
August 2019

Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples.

Front Genet 2019 20;10:211. Epub 2019 Mar 20.

Department of Internal Medicine, The University of New Mexico, Albuquerque, NM, United States.

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http://dx.doi.org/10.3389/fgene.2019.00211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435843PMC
March 2019

Architectures and accuracy of artificial neural network for disease classification from omics data.

BMC Genomics 2019 Mar 4;20(1):167. Epub 2019 Mar 4.

Department of Internal Medicine, University of New Mexico, Albuquerque, NM, 87131, USA.

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http://dx.doi.org/10.1186/s12864-019-5546-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399893PMC
March 2019

Corrigendum to: Single-nucleotide variants in human RNA: RNA editing and beyond.

Brief Funct Genomics 2019 02;18(1):40

Key Laboratory of Resource Biology and Biotechnology in Western China, School of Life Sciences, Northwest University,Xi'an, Shaanxi, China.

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http://dx.doi.org/10.1093/bfgp/ely041DOI Listing
February 2019

Cancer-specific expression quantitative loci are affected by expression dysregulation.

Brief Bioinform 2018 Nov 23. Epub 2018 Nov 23.

Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.

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https://academic.oup.com/bib/advance-article/doi/10.1093/bib
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http://dx.doi.org/10.1093/bib/bby108DOI Listing
November 2018

Bi-stream CNN Down Syndrome screening model based on genotyping array.

BMC Med Genomics 2018 Nov 20;11(Suppl 5):105. Epub 2018 Nov 20.

School of Medicine,The University of New Mexico, Albuquerque, 87131, NM, USA.

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https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12920-018-0416-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245487PMC
November 2018

Single-nucleotide variants in human RNA: RNA editing and beyond.

Brief Funct Genomics 2019 02;18(1):30-39

Key Laboratory of Resource Biology and Biotechnology in Western China, School of Life Sciences, Northwest University,Xi'an, Shaanxi, China.

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https://academic.oup.com/bfg/advance-article/doi/10.1093/bfg
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http://dx.doi.org/10.1093/bfgp/ely032DOI Listing
February 2019

Relation of Body Mass Index to Symptom Burden in Patients withAtrial Fibrillation.

Am J Cardiol 2018 07 1;122(2):235-241. Epub 2018 May 1.

Department of Medicine, University of Illinois at Chicago, Jesse Brown VA Medical Center, Chicago, Illinois; Departments of Medicine and Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028292PMC
July 2018

Quality and concordance of genotyping array data of 12,064 samples from 5840 cancer patients.

Genomics 2019 07 11;111(4):950-957. Epub 2018 Jun 11.

Department of Internal Medicine, University of New Mexico, Albuquerque, NM 87131, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546549PMC
July 2019

Genomic and transcriptomic characterization of the mitochondrial-rich oncocytic phenotype on a thyroid carcinoma background.

Mitochondrion 2019 05 6;46:123-133. Epub 2018 Apr 6.

Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal; Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), Porto, Portugal; Departamento de Patologia, Faculdade de Medicina da Universidade do Porto, Porto, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2018.04.001DOI Listing
May 2019

Current Research on Non-Coding Ribonucleic Acid (RNA).

Genes (Basel) 2017 Dec 5;8(12). Epub 2017 Dec 5.

Key Laboratory of Resource Biology and Biotechnology in Western China, School of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China.

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http://dx.doi.org/10.3390/genes8120366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748684PMC
December 2017

The discrepancy among single nucleotide variants detected by DNA and RNA high throughput sequencing data.

BMC Genomics 2017 Oct 3;18(Suppl 6):690. Epub 2017 Oct 3.

Department of Biostatistics, Vanderbilt University, 2220 Pierce Ave, 571 PRB, Nashville, TN, 37027, USA.

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http://dx.doi.org/10.1186/s12864-017-4022-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629567PMC
October 2017

Tri-allelic heteroplasmies, DNA-RNA differences and their polynucleotide tract associations in the mitochondrial genome.

Genomics 2017 Sep 29. Epub 2017 Sep 29.

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37232, United States; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, China; Department of Internal Medicine, University of New Mexico, Comprehensive Cancer Center, Albuquerque, NM, 87131, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2017.09.013DOI Listing
September 2017

Estimating relative mitochondrial DNA copy number using high throughput sequencing data.

Genomics 2017 10 19;109(5-6):457-462. Epub 2017 Jul 19.

Center for Quantitative Sciences, Vanderbilt University, Nashville, TN 37232, USA; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, China. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2017.07.002DOI Listing
October 2017

Power and sample size calculations for high-throughput sequencing-based experiments.

Brief Bioinform 2018 11;19(6):1247-1255

Department of Cancer Biology, Vanderbilt University.

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http://dx.doi.org/10.1093/bib/bbx061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291796PMC
November 2018

StrandScript: evaluation of Illumina genotyping array design and strand correction.

Bioinformatics 2017 Aug;33(15):2399-2401

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville TN, USA 37232.

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http://dx.doi.org/10.1093/bioinformatics/btx186DOI Listing
August 2017

Strategies for processing and quality control of Illumina genotyping arrays.

Brief Bioinform 2018 09;19(5):765-775

Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1093/bib/bbx012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171493PMC
September 2018

Mitochondrial Haplogroups Affect Severity But Not Prevalence of Diabetic Retinopathy.

Invest Ophthalmol Vis Sci 2017 02;58(2):1346-1351

Vanderbilt Genetics Institute and Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States.

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http://dx.doi.org/10.1167/iovs.16-20616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341621PMC
February 2017

Improvements and impacts of GRCh38 human reference on high throughput sequencing data analysis.

Genomics 2017 03 26;109(2):83-90. Epub 2017 Jan 26.

Department of Biostatistics, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1016/j.ygeno.2017.01.005DOI Listing
March 2017

STRATEGIES FOR EQUITABLE PHARMACOGENOMIC-GUIDED WARFARIN DOSING AMONG EUROPEAN AND AFRICAN AMERICAN INDIVIDUALS IN A CLINICAL POPULATION.

Pac Symp Biocomput 2017 ;22:545-556

Div. of Biomedical Informatics and Personalized Med., University of Colorado, 13001 E. 17th Pl. MS F-563 Aurora, CO 80045, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389380PMC
http://dx.doi.org/10.1142/9789813207813_0050DOI Listing
March 2017

Mitochondrial Haplogroups as a Risk Factor for Herpes Zoster.

Open Forum Infect Dis 2016 Oct 19;3(4):ofw184. Epub 2016 Oct 19.

Vanderbilt Genetics Institute; Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.

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http://dx.doi.org/10.1093/ofid/ofw184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088697PMC
October 2016

Practicability of mitochondrial heteroplasmy detection through an Illumina genotyping array.

Mitochondrion 2016 Nov 11;31:75-78. Epub 2016 Sep 11.

Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2016.08.018DOI Listing
November 2016

Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans.

Cell Metab 2016 07;24(1):91-103

Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287496PMC
July 2016

Mitochondria single nucleotide variation across six blood cell types.

Mitochondrion 2016 May 5;28:16-22. Epub 2016 Mar 5.

Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.mito.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755964PMC
May 2016

RNAseq by Total RNA Library Identifies Additional RNAs Compared to Poly(A) RNA Library.

Biomed Res Int 2015 12;2015:862130. Epub 2015 Oct 12.

Center for Quantitative Sciences, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1155/2015/862130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620295PMC
August 2016

Fine Time Scaling of Purifying Selection on Human Nonsynonymous mtDNA Mutations Based on the Worldwide Population Tree and Mother-Child Pairs.

Hum Mutat 2015 Nov 25;36(11):1100-11. Epub 2015 Aug 25.

Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, 4200-135, Portugal.

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http://dx.doi.org/10.1002/humu.22849DOI Listing
November 2015

Global human frequencies of predicted nuclear pathogenic variants and the role played by protein hydrophobicity in pathogenicity potential.

Sci Rep 2014 Nov 21;4:7155. Epub 2014 Nov 21.

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232-0700, USA.

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http://dx.doi.org/10.1038/srep07155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239565PMC
November 2014

Illumina human exome genotyping array clustering and quality control.

Nat Protoc 2014 Nov 16;9(11):2643-62. Epub 2014 Oct 16.

Vanderbilt Epidemiology Center, Vanderbilt University, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1038/nprot.2014.174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441213PMC
November 2014

Genome measures used for quality control are dependent on gene function and ancestry.

Bioinformatics 2015 Feb 8;31(3):318-23. Epub 2014 Oct 8.

Center for Quantitative Sciences and Department of Medicine and Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37212, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308666PMC
February 2015

Mitochondrial haplogroups are associated with severity of diabetic retinopathy.

Invest Ophthalmol Vis Sci 2014 Aug 12;55(9):5589-95. Epub 2014 Aug 12.

Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, United States.

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http://dx.doi.org/10.1167/iovs.14-15149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160073PMC
August 2014

High-throughput sequencing in mitochondrial DNA research.

Mitochondrion 2014 Jul 20;17:157-63. Epub 2014 May 20.

Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.mito.2014.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149223PMC
July 2014

Data from artificial models of mitochondrial DNA disorders are not always applicable to humans.

Cell Rep 2014 May;7(4):933-4

Université Paris-Descartes; Sorbonne Paris Cité, Institut IMAGINE and INSERM U781; Hôpital Necker-Enfants Malades, 149 rue de Sèvres, 75743 Paris, Cedex 15, France.

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http://dx.doi.org/10.1016/j.celrep.2014.05.005DOI Listing
May 2014

Epidermal nerve fiber density, oxidative stress, and mitochondrial haplogroups in HIV-infected Thais initiating therapy.

AIDS 2014 Jul;28(11):1625-33

aVanderbilt University, Nashville, Tennessee bUniversity of Hawaii, Honolulu, Hawaii, USA cSouth East Asia Research Collaboration with Hawaii dThai Red Cross AIDS Research Centre eHIV-NAT, Bangkok fQueen Savang Vadhana Memorial Hospital, Chonburi, Thailand gThe Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427899PMC
July 2014

Multi-perspective quality control of Illumina exome sequencing data using QC3.

Genomics 2014 May-Jun;103(5-6):323-8. Epub 2014 Apr 3.

Vanderbilt Ingram Cancer Center, Center for Quantitative Sciences, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2014.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755963PMC
January 2015

High proportion of heteroresistance in gyrA and gyrB in fluoroquinolone-resistant Mycobacterium tuberculosis clinical isolates.

Antimicrob Agents Chemother 2014 Jun 31;58(6):3270-5. Epub 2014 Mar 31.

Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Vanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1128/AAC.02066-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068501PMC
June 2014

The other genome: a systematic review of studies of mitochondrial DNA haplogroups and outcomes of HIV infection and antiretroviral therapy.

AIDS Rev 2013 Oct-Dec;15(4):213-20

Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001077PMC
August 2014

Comparative study of exome copy number variation estimation tools using array comparative genomic hybridization as control.

Biomed Res Int 2013 4;2013:915636. Epub 2013 Nov 4.

Center for Quantitative Sciences, Vanderbilt University, Nashville, TN 37027, USA.

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http://dx.doi.org/10.1155/2013/915636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835197PMC
June 2014

Recurrent tissue-specific mtDNA mutations are common in humans.

PLoS Genet 2013 Nov 7;9(11):e1003929. Epub 2013 Nov 7.

Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820769PMC
November 2013

Mitochondrial DNA rearrangements in health and disease--a comprehensive study.

Hum Mutat 2014 Jan 18;35(1):1-14. Epub 2013 Oct 18.

Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Rua Dr. Roberto Frias s/n, Porto, Portugal.

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http://dx.doi.org/10.1002/humu.22452DOI Listing
January 2014

Large scale comparison of gene expression levels by microarrays and RNAseq using TCGA data.

PLoS One 2013 20;8(8):e71462. Epub 2013 Aug 20.

Center for Quantitative Sciences, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071462PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748065PMC
April 2014

Finding the lost treasures in exome sequencing data.

Trends Genet 2013 Oct 22;29(10):593-9. Epub 2013 Aug 22.

Center for Human Genetics Research, Vanderbilt University, Nashville, TN, 37232, USA.

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http://dx.doi.org/10.1016/j.tig.2013.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926691PMC
October 2013

Evaluation of allele frequency estimation using pooled sequencing data simulation.

ScientificWorldJournal 2013 7;2013:895496. Epub 2013 Feb 7.

Vanderbilt Ingram Cancer Center, Nashville, TN, USA.

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http://dx.doi.org/10.1155/2013/895496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582166PMC
September 2013

MitoSeek: extracting mitochondria information and performing high-throughput mitochondria sequencing analysis.

Bioinformatics 2013 May 6;29(9):1210-1. Epub 2013 Mar 6.

Center for Quantitative Sciences, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492415PMC
May 2013

Mitochondrial genomics and antiretroviral therapy-associated metabolic complications in HIV-infected Black South Africans: a pilot study.

AIDS Res Hum Retroviruses 2013 Jul 15;29(7):1031-9. Epub 2013 Mar 15.

University of Cape Town Medical School, Department of Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1089/aid.2012.0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685683PMC
July 2013

Mutation dependance of the mitochondrial DNA copy number in the first stages of human embryogenesis.

Hum Mol Genet 2013 May 5;22(9):1867-72. Epub 2013 Feb 5.

Institut Imagine and INSERM U781, Sorbonne Paris Cité, Hôpital Necker-Enfants Malades, Université Paris-Descartes, 149 rue de Sèvres, Paris cedex 15, France.

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http://dx.doi.org/10.1093/hmg/ddt040DOI Listing
May 2013

Preventing the transmission of pathogenic mitochondrial DNA mutations: Can we achieve long-term benefits from germ-line gene transfer?

Hum Reprod 2013 Mar 7;28(3):554-9. Epub 2013 Jan 7.

Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1093/humrep/des439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3571501PMC
March 2013

The effect of strand bias in Illumina short-read sequencing data.

BMC Genomics 2012 Nov 24;13:666. Epub 2012 Nov 24.

Vanderbilt Ingram Cancer Center, Nashville, TN, USA.

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http://dx.doi.org/10.1186/1471-2164-13-666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532123PMC
November 2012

Universal heteroplasmy of human mitochondrial DNA.

Hum Mol Genet 2013 Jan 16;22(2):384-90. Epub 2012 Oct 16.

Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastleupon-Tyne NE1 3BZ, UK.

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http://dx.doi.org/10.1093/hmg/dds435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526165PMC
January 2013

Mitochondrial DNA deletions are associated with non-B DNA conformations.

Nucleic Acids Res 2012 Sep 31;40(16):7606-21. Epub 2012 May 31.

Institute of Molecular Pathology and Immunology, University of Porto (IPATIMUP), Rua Dr Roberto Frias s/n, 4200-465 Porto, Portugal.

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http://dx.doi.org/10.1093/nar/gks500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439893PMC
September 2012

Unique mitochondrial DNA in highly inbred feral cattle.

Mitochondrion 2012 Jul 17;12(4):438-40. Epub 2012 May 17.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1016/j.mito.2012.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485552PMC
July 2012

Adult-onset spinocerebellar ataxia syndromes due to MTATP6 mutations.

J Neurol Neurosurg Psychiatry 2012 Sep 10;83(9):883-6. Epub 2012 May 10.

Institute of Genetic Medicine, Central Parkway, Newcastle, UK.

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http://dx.doi.org/10.1136/jnnp-2012-302568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034166PMC
September 2012

Correlated tissue expression of genes of cytoplasmic and mitochondrial nucleotide metabolisms in normal tissues is disrupted in transformed tissues.

Nucleosides Nucleotides Nucleic Acids 2012 ;31(2):112-29

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee 37232-0700, USA.

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http://dx.doi.org/10.1080/15257770.2011.644101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464496PMC
June 2012

Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors.

BMC Cancer 2012 Feb 2;12:53. Epub 2012 Feb 2.

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1186/1471-2407-12-53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342922PMC
February 2012

Epigenetics, epidemiology and mitochondrial DNA diseases.

Int J Epidemiol 2012 Feb 28;41(1):177-87. Epub 2012 Jan 28.

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 3BZ, UK.

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http://dx.doi.org/10.1093/ije/dyr232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304530PMC
February 2012

Replication pauses of the wild-type and mutant mitochondrial DNA polymerase gamma: a simulation study.

PLoS Comput Biol 2011 Nov 17;7(11):e1002287. Epub 2011 Nov 17.

Center for Human Genetic Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1371/journal.pcbi.1002287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219627PMC
November 2011

Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication.

PLoS Comput Biol 2011 Aug 4;7(8):e1002078. Epub 2011 Aug 4.

Center for Human Genetics Research, Department of Molecular Biology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1371/journal.pcbi.1002078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150320PMC
August 2011

A review comparing deoxyribonucleoside triphosphate (dNTP) concentrations in the mitochondrial and cytoplasmic compartments of normal and transformed cells.

Nucleosides Nucleotides Nucleic Acids 2011 May;30(5):317-39

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37232-0700, USA.

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http://dx.doi.org/10.1080/15257770.2011.586955DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210641PMC
May 2011

Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations.

Nat Genet 2011 Jun 26;43(8):806-10. Epub 2011 Jun 26.

Mitochondrial Research Group, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1038/ng.863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223397PMC
June 2011

Poor correlations in the levels of pathogenic mitochondrial DNA mutations in polar bodies versus oocytes and blastomeres in humans.

Am J Hum Genet 2011 Apr;88(4):494-8

Université Paris-Descartes, Faculté de Médecine, Unité INSERM U781, Service de Génétique Médicale, Hôpital Necker-Enfants Malades (Assistance Publique-Hôpitaux de Paris), 149 rue de Sèvres, 75743 Paris Cedex 15, France.

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http://dx.doi.org/10.1016/j.ajhg.2011.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071907PMC
April 2011

Comparing phylogeny and the predicted pathogenicity of protein variations reveals equal purifying selection across the global human mtDNA diversity.

Am J Hum Genet 2011 Apr 31;88(4):433-9. Epub 2011 Mar 31.

Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), Porto 4200-465, Portugal.

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http://dx.doi.org/10.1016/j.ajhg.2011.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071914PMC
April 2011

POLG mutations cause decreased mitochondrial DNA repopulation rates following induced depletion in human fibroblasts.

Biochim Biophys Acta 2011 Mar 5;1812(3):321-5. Epub 2010 Dec 5.

Mitochondrial Research Group, Institute of Human Genetics, Newcastle University, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK.

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http://dx.doi.org/10.1016/j.bbadis.2010.11.012DOI Listing
March 2011

The Bcl-2-associated death promoter (BAD) lowers the threshold at which the Bcl-2-interacting domain death agonist (BID) triggers mitochondria disintegration.

J Theor Biol 2011 Feb 3;271(1):114-23. Epub 2010 Dec 3.

Integrated Cellular Responses Laboratory-Virginia Polytechnic Institute & State University, Department of Biological Sciences, Blacksburg, VA 24061, USA.

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http://dx.doi.org/10.1016/j.jtbi.2010.11.040DOI Listing
February 2011