David C Page

David C Page

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Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing.

G3 (Bethesda) 2019 05 7;9(5):1481-1486. Epub 2019 May 7.

Whitehead Institute, 455 Main Street, Cambridge, MA 02142

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http://dx.doi.org/10.1534/g3.119.300582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505145PMC
May 2019

Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements.

Nat Genet 2019 04 4;51(4):705-715. Epub 2019 Mar 4.

Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41588-019-0360-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441390PMC
April 2019

A strategic research alliance: Turner syndrome and sex differences.

Am J Med Genet C Semin Med Genet 2019 Mar 20;181(1):59-67. Epub 2019 Feb 20.

Whitehead Institute, Cambridge, Massachusetts.

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http://dx.doi.org/10.1002/ajmg.c.31677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414291PMC
March 2019

Corrigendum to "Isolating mitotic and meiotic germ cells from male mice by developmental synchronization, staging, and sorting" [Dev. Biol. 443 (2018) 19-34].

Dev Biol 2019 01 8;445(1):113. Epub 2018 Nov 8.

Whitehead Institute, 455 Main Street, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Whitehead Institute, 455 Main Street, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2018.10.021DOI Listing
January 2019

Isolating mitotic and meiotic germ cells from male mice by developmental synchronization, staging, and sorting.

Dev Biol 2018 11 25;443(1):19-34. Epub 2018 Aug 25.

Whitehead Institute, 455 Main Street, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Whitehead Institute, 455 Main Street, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2018.08.009DOI Listing
November 2018

Selection Has Countered High Mutability to Preserve the Ancestral Copy Number of Y Chromosome Amplicons in Diverse Human Lineages.

Am J Hum Genet 2018 08;103(2):261-275

Whitehead Institute, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Whitehead Institute, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080837PMC
August 2018

Conserved microRNA targeting reveals preexisting gene dosage sensitivities that shaped amniote sex chromosome evolution.

Genome Res 2018 04 15;28(4):474-483. Epub 2018 Feb 15.

Whitehead Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1101/gr.230433.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880238PMC
April 2018

Cost-effective high-throughput single-haplotype iterative mapping and sequencing for complex genomic structures.

Nat Protoc 2018 04 22;13(4):787-809. Epub 2018 Mar 22.

Whitehead Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nprot.2018.019DOI Listing
April 2018

Periodic production of retinoic acid by meiotic and somatic cells coordinates four transitions in mouse spermatogenesis.

Proc Natl Acad Sci U S A 2017 11 6;114(47):E10132-E10141. Epub 2017 Nov 6.

Whitehead Institute, Cambridge, MA 02142;

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http://dx.doi.org/10.1073/pnas.1710837114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703301PMC
November 2017

Meioc maintains an extended meiotic prophase I in mice.

PLoS Genet 2017 04 5;13(4):e1006704. Epub 2017 Apr 5.

Whitehead Institute, Cambridge, MA, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006704DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397071PMC
April 2017

Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining.

Nat Cell Biol 2017 Jan 5;19(1):68-75. Epub 2016 Dec 5.

Ludwig Institute for Cancer Research and Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/ncb3450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539760PMC
January 2017

The Biology and Evolution of Mammalian Y Chromosomes.

Annu Rev Genet 2015 6;49:507-27. Epub 2015 Oct 6.

Whitehead Institute, Howard Hughes Medical Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142; email:

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http://dx.doi.org/10.1146/annurev-genet-112414-055311DOI Listing
September 2016

Parallel evolution of male germline epigenetic poising and somatic development in animals.

Nat Genet 2016 08 13;48(8):888-94. Epub 2016 Jun 13.

Whitehead Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3591DOI Listing
August 2016

A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.

J Cell Biol 2016 05 2;213(3):315-28. Epub 2016 May 2.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139

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http://dx.doi.org/10.1083/jcb.201510117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862331PMC
May 2016

The history of the Y chromosome in man.

Nat Genet 2016 05;48(6):588-9

Whitehead Institute, Howard Hughes Medical Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3580DOI Listing
May 2016

Developing a utility decision framework to evaluate predictive models in breast cancer risk estimation.

J Med Imaging (Bellingham) 2015 Oct 17;2(4):041005. Epub 2015 Aug 17.

University of Wisconsin-Madison , Department of Radiology, 600 Highland Avenue, Madison, Wisconsin 53792, United States.

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http://dx.doi.org/10.1117/1.JMI.2.4.041005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718446PMC
October 2015

TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse.

EMBO Mol Med 2015 Sep;7(9):1198-210

Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA

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http://dx.doi.org/10.15252/emmm.201404967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568952PMC
September 2015

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary.

PLoS Genet 2015 Sep 17;11(9):e1005531. Epub 2015 Sep 17.

Whitehead Institute, Cambridge, Massachusetts, United States of America; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Howard Hughes Medical Institute, Whitehead Institute, Cambridge, Massachusetts, United States of America.

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http://pagelab.wi.mit.edu/pdf/2015-Soh.pdf
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http://dx.plos.org/10.1371/journal.pgen.1005531
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http://dx.doi.org/10.1371/journal.pgen.1005531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574967PMC
September 2015

Periodic retinoic acid-STRA8 signaling intersects with periodic germ-cell competencies to regulate spermatogenesis.

Proc Natl Acad Sci U S A 2015 May 20;112(18):E2347-56. Epub 2015 Apr 20.

Whitehead Institute, Cambridge, MA 02142; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139; and Howard Hughes Medical Institute, Whitehead Institute, Cambridge, MA 02142

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http://dx.doi.org/10.1073/pnas.1505683112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426408PMC
May 2015

Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.

PLoS Genet 2015 Mar 4;11(3):e1005019. Epub 2015 Mar 4.

Whitehead Institute, Cambridge, Massachusetts, United States of America; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Howard Hughes Medical Institute, Whitehead Institute, Cambridge, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349450PMC
March 2015

The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice.

J Biol Chem 2014 Dec 15;289(50):34490-502. Epub 2014 Oct 15.

From the Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, and

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http://dx.doi.org/10.1074/jbc.M114.604132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263858PMC
December 2014

Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes.

Cell 2014 Nov 30;159(4):800-13. Epub 2014 Oct 30.

Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Whitehead Institute, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.09.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260969PMC
November 2014

Poised chromatin in the mammalian germ line.

Development 2014 Oct;141(19):3619-26

Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02142, USA Howard Hughes Medical Institute, Whitehead Institute, Cambridge, MA 02142, USA Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1242/dev.113027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197577PMC
October 2014

Retinoic acid activates two pathways required for meiosis in mice.

PLoS Genet 2014 Aug 7;10(8):e1004541. Epub 2014 Aug 7.

Whitehead Institute, Cambridge, Massachusetts, United States of America; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America; Howard Hughes Medical Institute, Whitehead Institute, Cambridge, Massachusetts, United States of America.

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http://pagelab.wi.mit.edu/pdf/2014-Koubova.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004541
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http://dx.doi.org/10.1371/journal.pgen.1004541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125102PMC
August 2014

Gata4 is required for formation of the genital ridge in mice.

PLoS Genet 2013 11;9(7):e1003629. Epub 2013 Jul 11.

Whitehead Institute, Howard Hughes Medical Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708810PMC
January 2014

Intrachromosomal homologous recombination between inverted amplicons on opposing Y-chromosome arms.

Genomics 2013 Oct 2;102(4):257-64. Epub 2013 May 2.

Whitehead Institute, Howard Hughes Medical Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2013.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785290PMC
October 2013

Oocyte differentiation is genetically dissociable from meiosis in mice.

Nat Genet 2013 Aug 16;45(8):877-83. Epub 2013 Jun 16.

Whitehead Institute, Cambridge, Massachusetts, USA.

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http://www.nature.com/articles/ng.2672
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http://dx.doi.org/10.1038/ng.2672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747777PMC
August 2013

Tumor suppressor gene Rb is required for self-renewal of spermatogonial stem cells in mice.

Proc Natl Acad Sci U S A 2013 Jul 15;110(31):12685-90. Epub 2013 Jul 15.

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.1311548110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732951PMC
July 2013

Sequencing of rhesus macaque Y chromosome clarifies origins and evolution of the DAZ (Deleted in AZoospermia) genes.

Bioessays 2012 Dec 10;34(12):1035-44. Epub 2012 Oct 10.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.

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http://dx.doi.org/10.1002/bies.201200066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581811PMC
December 2012

Genetics of germ cell development.

Nat Rev Genet 2012 Nov 9;13(11):781-94. Epub 2012 Oct 9.

Howard Hughes Medical Institute, Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nrg3294DOI Listing
November 2012

Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice.

Development 2012 May 21;139(9):1577-86. Epub 2012 Mar 21.

Department of Genetics, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1242/dev.076851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3317965PMC
May 2012

Identification of avian W-linked contigs by short-read sequencing.

BMC Genomics 2012 May 14;13:183. Epub 2012 May 14.

Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, New York, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-13-183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428670PMC
May 2012

Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells.

Proc Natl Acad Sci U S A 2011 May 19;108(18):7443-8. Epub 2011 Apr 19.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.1104501108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088606PMC
May 2011

Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition.

Nature 2010 Jul 11;466(7306):612-6. Epub 2010 Jul 11.

Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature09172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943333PMC
July 2010

The airway, breathing and orthodontics.

Todays FDA 2010 Mar-Apr;22(2):43-7

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June 2010

Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content.

Nature 2010 Jan 13;463(7280):536-9. Epub 2010 Jan 13.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature08700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653425PMC
January 2010

Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection.

Am J Hum Genet 2009 Dec;85(6):923-8

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.ajhg.2009.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790577PMC
December 2009

Isodicentric Y chromosomes and sex disorders as byproducts of homologous recombination that maintains palindromes.

Cell 2009 Sep;138(5):855-69

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009286740900979
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http://dx.doi.org/10.1016/j.cell.2009.07.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616640PMC
September 2009

Germ cell-intrinsic and -extrinsic factors govern meiotic initiation in mouse embryos.

Science 2008 Dec;322(5908):1685-7

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1126/science.1166340DOI Listing
December 2008

Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.

Proc Natl Acad Sci U S A 2008 Sep 17;105(39):14976-80. Epub 2008 Sep 17.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.0807297105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542382PMC
September 2008

The mouse X chromosome is enriched for multicopy testis genes showing postmeiotic expression.

Nat Genet 2008 Jun 4;40(6):794-9. Epub 2008 May 4.

Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ng.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740655PMC
June 2008

MSY Breakpoint Mapper, a database of sequence-tagged sites useful in defining naturally occurring deletions in the human Y chromosome.

Nucleic Acids Res 2008 Jan 26;36(Database issue):D809-14. Epub 2007 Oct 26.

Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1093/nar/gkm849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238960PMC
January 2008

Abnormal sperm in mice lacking the Taf7l gene.

Mol Cell Biol 2007 Apr 22;27(7):2582-9. Epub 2007 Jan 22.

Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1128/MCB.01722-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899882PMC
April 2007

The mysteries of sexual identity. The germ cell's perspective.

Science 2007 Apr;316(5823):400-1

Howard Hughes Medical Institute, Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1126/science.1142109DOI Listing
April 2007

In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replication.

Nat Genet 2006 Dec 19;38(12):1430-4. Epub 2006 Nov 19.

Howard Hughes Medical Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ng1919DOI Listing
December 2006

Has the chimpanzee Y chromosome been sequenced?

Nat Genet 2006 Aug;38(8):853-4; author reply 854-5

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http://dx.doi.org/10.1038/ng0806-853bDOI Listing
August 2006

High mutation rates have driven extensive structural polymorphism among human Y chromosomes.

Nat Genet 2006 Apr 26;38(4):463-7. Epub 2006 Feb 26.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ng1754DOI Listing
April 2006

Interview with Dr. David C. Page. 2002 AAFO Clinician of the Year.

Authors:
David C Page

Funct Orthod 2005 Summer-Fall;22(2):26-8

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April 2006

Retinoic acid regulates sex-specific timing of meiotic initiation in mice.

Proc Natl Acad Sci U S A 2006 Feb 6;103(8):2474-9. Epub 2006 Feb 6.

Howard Hughes Medical Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1073/pnas.0510813103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413806PMC
February 2006

Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.

Dev Biol 2005 Dec 28;288(2):309-16. Epub 2005 Nov 28.

Howard Hughes Medical Institute, Whitehead Institute, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.ydbio.2005.06.032DOI Listing
December 2005

Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.

Hum Mol Genet 2005 Oct 23;14(19):2911-8. Epub 2005 Aug 23.

Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19004, USA.

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http://dx.doi.org/10.1093/hmg/ddi322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994333PMC
October 2005

RNF17, a component of the mammalian germ cell nuage, is essential for spermiogenesis.

Development 2005 Sep 10;132(18):4029-39. Epub 2005 Aug 10.

Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1242/dev.02003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1994335PMC
September 2005

Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee.

Nature 2005 Sep;437(7055):100-3

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature04101DOI Listing
September 2005

Preparing for the exam.

Authors:
David C Page

J Am Dent Assoc 2004 Dec;135(12):1662, 1164; author reply 1664, 1167-8

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http://dx.doi.org/10.14219/jada.archive.2004.0102DOI Listing
December 2004

An X-to-autosome retrogene is required for spermatogenesis in mice.

Nat Genet 2004 Aug 18;36(8):872-6. Epub 2004 Jul 18.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ng1390DOI Listing
August 2004

Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis.

Dev Dyn 2004 Jun;230(2):210-5

Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1002/dvdy.20042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046253PMC
June 2004

Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis.

Dev Biol 2004 Apr;268(2):429-40

Department of Medicine, The Children's Hospital, and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ydbio.2003.12.033DOI Listing
April 2004

2003 Curt Stern Award address. On low expectation exceeded; or, the genomic salvation of the Y chromosome.

Authors:
David C Page

Am J Hum Genet 2004 Mar;74(3):399-402

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, 02142, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182254PMC
http://dx.doi.org/10.1086/382659DOI Listing
March 2004

Early orthodontics. 5 new steps to better care.

Authors:
David C Page

Dent Today 2004 Feb;23(2):112-6

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February 2004

Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice.

BMC Dev Biol 2004 Feb 23;4. Epub 2004 Feb 23.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1186/1471-213X-4-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC362866PMC
February 2004

"Real" early orthodontic treatment. From birth to age 8.

Authors:
David C Page

Funct Orthod 2003 Spring-Summer;20(1-2):48-54, 56-8

Page Associates Family Dentistry, Baltimore, USA.

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December 2003

Polymorphism for a 1.6-Mb deletion of the human Y chromosome persists through balance between recurrent mutation and haploid selection.

Nat Genet 2003 Nov 5;35(3):247-51. Epub 2003 Oct 5.

Howard Hughes Medical Institute, Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ng1250DOI Listing
November 2003

Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave.

Dev Biol 2003 Oct;262(2):303-12

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/s0012-1606(03)00391-9DOI Listing
October 2003

The pituitary-testicular axis in Klinefelter's syndrome and in oligo-azoospermic patients with and without deletions of the Y chromosome long arm.

Clin Endocrinol (Oxf) 2003 Aug;59(2):214-22

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, 02142, USA.

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http://dx.doi.org/10.1046/j.1365-2265.2003.01828.xDOI Listing
August 2003

Abundant gene conversion between arms of palindromes in human and ape Y chromosomes.

Nature 2003 Jun;423(6942):873-6

Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature01723DOI Listing
June 2003

The jaws and early orthodontics.

Authors:
David C Page

Funct Orthod 2002 ;19(4):26-7

Page Associates, Family Dentistry, Baltimore, Maryland, USA.

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May 2003

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

Development 2003 Apr;130(8):1673-80

Howard Hughes Medical Institute, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1242/dev.00366DOI Listing
April 2003

Your Jaws--Your Life.

Authors:
David C Page

Funct Orthod 2002 ;19(3):36-8

Page Associates Family Dentistry, Baltimore, Maryland, USA.

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January 2003

Velocardiofacial syndrome in an unexplained XX male.

Am J Med Genet A 2003 Jan;116A(1):77-9

Genetic Diagnostic Laboratory, T.C. Thompson Children's Hospital, Chattanooga, Tennessee 37403, USA.

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http://dx.doi.org/10.1002/ajmg.a.10833DOI Listing
January 2003

Sexually dimorphic gene expression in the developing mouse gonad.

Gene Expr Patterns 2002 Dec;2(3-4):359-67

Howard Hughes Medical Institute, Whitehead Institute, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

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December 2002

Clinical characterization of 42 oligospermic or azoospermic men with microdeletion of the AZFc region of the Y chromosome, and of 18 children conceived via ICSI.

Hum Reprod 2002 Nov;17(11):2813-24

Department of Urology, Boston University School of Medicine, 720 Harrison Avenue, Boston, MA 02118, USA.

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http://dx.doi.org/10.1093/humrep/17.11.2813DOI Listing
November 2002

Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure.

Am J Hum Genet 2002 Oct 20;71(4):906-22. Epub 2002 Sep 20.

Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge 02142, USA.

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http://dx.doi.org/10.1086/342928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419997PMC
October 2002

Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.

Hum Mol Genet 2002 Sep;11(19):2341-6

Howard Hughes Medical Institute, Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1093/hmg/11.19.2341DOI Listing
September 2002