David C Klein

David C Klein

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David C Klein

Publications by authors named "David C Klein"

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Genomic methods in profiling DNA accessibility and factor localization.

Chromosome Res 2020 Mar 27;28(1):69-85. Epub 2019 Nov 27.

Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, 15260, USA.

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http://dx.doi.org/10.1007/s10577-019-09619-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125251PMC
March 2020

Circadian regulation and molecular role of the Bsx homeobox gene in the adult pineal gland.

J Pineal Res 2020 Mar 30;68(2):e12629. Epub 2019 Dec 30.

Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/jpi.12629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122731PMC
March 2020

The Lhx4 homeobox transcript in the rat pineal gland: Adrenergic regulation and impact on transcripts encoding melatonin-synthesizing enzymes.

J Pineal Res 2020 Jan 11;68(1):e12616. Epub 2019 Nov 11.

Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jpi.12616
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http://dx.doi.org/10.1111/jpi.12616DOI Listing
January 2020

Chromatin regulation and dynamics in stem cells.

Curr Top Dev Biol 2020 30;138:1-71. Epub 2019 Dec 30.

Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.ctdb.2019.11.002DOI Listing
December 2019

Single Cell Sequencing of the Pineal Gland: The Next Chapter.

Front Endocrinol (Lausanne) 2019 20;10:590. Epub 2019 Sep 20.

Office of the Scientific Director, Intramural Research Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fendo.2019.00590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764290PMC
September 2019

Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression.

PLoS One 2018 22;13(10):e0205883. Epub 2018 Oct 22.

Office of the Scientific Director, Intramural Research Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205883PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197868PMC
April 2019

Daily Rhythm in Plasma N-acetyltryptamine.

J Biol Rhythms 2017 06 3;32(3):195-211. Epub 2017 May 3.

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics.

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http://dx.doi.org/10.1177/0748730417700458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571864PMC
June 2017

Andreas Oksche.

J Biol Rhythms 2017 04;32(2):99-100

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http://dx.doi.org/10.1177/0748730417703558DOI Listing
April 2017

Alternative Isoform Analysis of Ttc8 Expression in the Rat Pineal Gland Using a Multi-Platform Sequencing Approach Reveals Neural Regulation.

PLoS One 2016;11(9):e0163590. Epub 2016 Sep 29.

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, 20892, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163590PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042479PMC
September 2016

Neurotranscriptomics: The Effects of Neonatal Stimulus Deprivation on the Rat Pineal Transcriptome.

PLoS One 2015 14;10(9):e0137548. Epub 2015 Sep 14.

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137548PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569390PMC
June 2016

Melatonin Synthesis: Acetylserotonin O-Methyltransferase (ASMT) Is Strongly Expressed in a Subpopulation of Pinealocytes in the Male Rat Pineal Gland.

Endocrinology 2016 05 7;157(5):2028-40. Epub 2016 Mar 7.

Department of Neuroscience and Pharmacology (M.F.R., M.M.), Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark; and Section on Neuroendocrinology (M.F.R., S.L.C., F.G.A., J.L.W., D.C.K.), Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1210/en.2015-1888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870883PMC
May 2016

The Lhx9 homeobox gene controls pineal gland development and prevents postnatal hydrocephalus.

Brain Struct Funct 2015 20;220(3):1497-509. Epub 2014 Mar 20.

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 49 Convent Drive, Room 6A82, Bethesda, MD, 20892-4510, USA.

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http://dx.doi.org/10.1007/s00429-014-0740-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197116PMC
January 2016

Drastic neofunctionalization associated with evolution of the timezyme AANAT 500 Mya.

Proc Natl Acad Sci U S A 2014 Jan 18;111(1):314-9. Epub 2013 Dec 18.

Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7232 and Université Pierre et Marie Curie-Paris 6, Laboratoire Aragó, F-66650 Banyuls-sur-Mer, France.

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http://dx.doi.org/10.1073/pnas.1312634110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890824PMC
January 2014

Female-specific induction of rat pituitary dentin matrix protein-1 by GnRH.

Mol Endocrinol 2013 Nov 1;27(11):1840-55. Epub 2013 Oct 1.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, Building 49, Room 6A-36, 49 Convent Drive, Bethesda, Maryland 20892-4510. or

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http://dx.doi.org/10.1210/me.2013-1068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805844PMC
November 2013

Homeobox genes in the rodent pineal gland: roles in development and phenotype maintenance.

Neurochem Res 2013 Jun 18;38(6):1100-12. Epub 2012 Oct 18.

Department of Neuroscience and Pharmacology, Panum Institute 24.2, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, Copenhagen 2200, Denmark.

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http://dx.doi.org/10.1007/s11064-012-0906-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570627PMC
June 2013

RGS2 is a feedback inhibitor of melatonin production in the pineal gland.

FEBS Lett 2013 May 21;587(9):1392-8. Epub 2013 Mar 21.

The Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.febslet.2013.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119756PMC
May 2013

NeuroD1 is required for survival of photoreceptors but not pinealocytes: results from targeted gene deletion studies.

J Neurochem 2012 Oct 16;123(1):44-59. Epub 2012 Aug 16.

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2012.07870.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441145PMC
October 2012

Circadian changes in long noncoding RNAs in the pineal gland.

Proc Natl Acad Sci U S A 2012 Aug 3;109(33):13319-24. Epub 2012 Aug 3.

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1207748109
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http://dx.doi.org/10.1073/pnas.1207748109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421215PMC
August 2012

MicroRNAs in the pineal gland: miR-483 regulates melatonin synthesis by targeting arylalkylamine N-acetyltransferase.

J Biol Chem 2012 Jul;287(30):25312-24

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408182PMC
http://dx.doi.org/10.1074/jbc.M112.356733DOI Listing
July 2012

Molecular evolution of multiple arylalkylamine N-acetyltransferase (AANAT) in fish.

Mar Drugs 2011 24;9(5):906-21. Epub 2011 May 24.

Department of Neurobiology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.3390/md9050906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111191PMC
November 2011

Crx broadly modulates the pineal transcriptome.

J Neurochem 2011 Oct 2;119(2):262-74. Epub 2011 Sep 2.

Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07405.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422619PMC
October 2011

Norepinephrine causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+.

Endocrinology 2011 Oct 9;152(10):3842-51. Epub 2011 Aug 9.

Department of Cellular and Molecular Neuroendocrinology, Institute of Physiology of the Academy of Sciences of the Czech Republic, 142 20 Prague 4, Czech Republic.

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http://dx.doi.org/10.1210/en.2011-1180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176642PMC
October 2011

Rax : developmental and daily expression patterns in the rat pineal gland and retina.

J Neurochem 2011 Sep 8;118(6):999-1007. Epub 2011 Aug 8.

Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07385.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166365PMC
September 2011

Global daily dynamics of the pineal transcriptome.

Cell Tissue Res 2011 Apr 8;344(1):1-11. Epub 2011 Feb 8.

Instituto Tecnológico de Chascomús (Instituto de Investigaciones Biotecnológicas-Instituto Tecnológico de Chascomús), Camino Circunvalación Laguna km 6 cc164, B7130IWA, Chascomús, Argentina.

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http://dx.doi.org/10.1007/s00441-010-1094-1DOI Listing
April 2011

A neuroanatomical and physiological study of the non-image forming visual system of the cone-rod homeobox gene (Crx) knock out mouse.

Brain Res 2010 Jul 31;1343:54-65. Epub 2010 May 31.

Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.brainres.2010.04.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652412PMC
July 2010

Evolution of AANAT: expansion of the gene family in the cephalochordate amphioxus.

BMC Evol Biol 2010 May 25;10:154. Epub 2010 May 25.

Section on Neuroendocrinology, Program in Developmental Endocrinology and Genetics, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1186/1471-2148-10-154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897805PMC
May 2010

Thyroid hormone and adrenergic signaling interact to control pineal expression of the dopamine receptor D4 gene (Drd4).

Mol Cell Endocrinol 2010 Jan 29;314(1):128-35. Epub 2009 May 29.

Section on Neuroendocrinology, Program on Developmental Endocrinology and Genetics, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.mce.2009.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783391PMC
January 2010

Pineal function: impact of microarray analysis.

Mol Cell Endocrinol 2010 Jan 19;314(2):170-83. Epub 2009 Jul 19.

Section on Neuroendocrinology, Program on Developmental Endocrinology and Genetics, NICHD, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.mce.2009.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138125PMC
January 2010

Muscleblind-like 2: circadian expression in the mammalian pineal gland is controlled by an adrenergic-cAMP mechanism.

J Neurochem 2009 Jul 19;110(2):756-64. Epub 2009 May 19.

Program on Developmental Endocrinology and Genetics, Section on Neuroendocrinology, The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2009.06184.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766844PMC
July 2009

Transcriptome analysis of the zebrafish pineal gland.

Dev Dyn 2009 Jul;238(7):1813-26

Laboratory of Molecular Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, Maryland, USA.

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http://doi.wiley.com/10.1002/dvdy.21988
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http://dx.doi.org/10.1002/dvdy.21988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946851PMC
July 2009

A new cis-acting regulatory element driving gene expression in the zebrafish pineal gland.

Bioinformatics 2009 Mar 15;25(5):559-62. Epub 2009 Jan 15.

Department of Neurobiology, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1093/bioinformatics/btp031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559713PMC
March 2009

Developmental and daily expression of the Pax4 and Pax6 homeobox genes in the rat retina: localization of Pax4 in photoreceptor cells.

J Neurochem 2009 Jan 19;108(1):285-94. Epub 2008 Nov 19.

Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05765.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528810PMC
January 2009

Localization and regulation of dopamine receptor D4 expression in the adult and developing rat retina.

Exp Eye Res 2008 Nov 20;87(5):471-7. Epub 2008 Aug 20.

Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.exer.2008.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597030PMC
November 2008

Evidence that proline focuses movement of the floppy loop of arylalkylamine N-acetyltransferase (EC 2.3.1.87).

J Biol Chem 2008 May 24;283(21):14552-8. Epub 2008 Mar 24.

Section of Neuroendocrinology, Program on Developmental Endocrinology and Genetics, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1074/jbc.M800593200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386931PMC
May 2008

Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor alpha-subunit expression in the mammalian pinealocyte: a neuroendocrine/immune response link?

J Biol Chem 2007 Nov 29;282(45):32758-64. Epub 2007 Aug 29.

Section on Neuroendocrinology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1074/jbc.M705950200DOI Listing
November 2007

De novo discovery of serotonin N-acetyltransferase inhibitors.

J Med Chem 2007 Nov 9;50(22):5330-8. Epub 2007 Oct 9.

Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA.

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https://pubs.acs.org/doi/10.1021/jm0706463
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http://dx.doi.org/10.1021/jm0706463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531295PMC
November 2007

NeuroD1: developmental expression and regulated genes in the rodent pineal gland.

J Neurochem 2007 Aug;102(3):887-99

Section on Neuroendocrinology, Office of the Scientific Director, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04605.xDOI Listing
August 2007

Ontogenetic expression of the Otx2 and Crx homeobox genes in the retina of the rat.

Exp Eye Res 2007 Jul 19;85(1):65-73. Epub 2007 Mar 19.

Department of Neuroscience and Pharmacology, University of Copenhagen, Panum Institute, Blegdamsvej 3, DK-2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.exer.2007.02.016DOI Listing
July 2007

Rodent Aanat: intronic E-box sequences control tissue specificity but not rhythmic expression in the pineal gland.

Mol Cell Endocrinol 2007 May 15;270(1-2):43-9. Epub 2007 Feb 15.

School of Biosciences, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1016/j.mce.2007.02.003DOI Listing
May 2007

Daily rhythm in pineal phosphodiesterase (PDE) activity reflects adrenergic/3',5'-cyclic adenosine 5'-monophosphate induction of the PDE4B2 variant.

Endocrinology 2007 Apr 4;148(4):1475-85. Epub 2007 Jan 4.

Section on Neuroendocrinology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/en.2006-1420DOI Listing
April 2007

The pineal gene expression party: who's the surprise guest?

Authors:
David C Klein

Endocrinology 2007 Apr;148(4):1463-4

Section on Neuroendocrinology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/en.2007-0077DOI Listing
April 2007

Enzymatic and cellular study of a serotonin N-acetyltransferase phosphopantetheine-based prodrug.

Bioorg Med Chem 2007 Mar 13;15(5):2147-55. Epub 2006 Dec 13.

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.bmc.2006.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1831523PMC
March 2007

Arylalkylamine N-acetyltransferase: "the Timezyme".

Authors:
David C Klein

J Biol Chem 2007 Feb 12;282(7):4233-7. Epub 2006 Dec 12.

Section on Neuroendocrinology, Office of Scientific Director, NICHD, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.R600036200DOI Listing
February 2007

Evolution of the vertebrate pineal gland: the AANAT hypothesis.

Authors:
David C Klein

Chronobiol Int 2006 ;23(1-2):5-20

Department of Health and Human Services, Section on Neuroendocrinology, Office of the Scientific Director, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20893, USA.

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http://www.tandfonline.com/doi/full/10.1080/0742052050054583
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http://dx.doi.org/10.1080/07420520500545839DOI Listing
August 2006

The perivascular phagocyte of the mouse pineal gland: an antigen-presenting cell.

Chronobiol Int 2006 ;23(1-2):393-401

Institute of Medical Anatomy, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1080/07420520500521855DOI Listing
August 2006

Evolution of arylalkylamine N-acetyltransferase: emergence and divergence.

Mol Cell Endocrinol 2006 Jun 11;252(1-2):2-10. Epub 2006 May 11.

Section on Neuroendocrinology, Office of the Scientific Director, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20894, USA.

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http://dx.doi.org/10.1016/j.mce.2006.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1578506PMC
June 2006

Starting the zebrafish pineal circadian clock with a single photic transition.

Endocrinology 2006 May 23;147(5):2273-9. Epub 2006 Feb 23.

Laboratoire Aragó, Observatoire Océanologique de Banyuls, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7628, Université de Paris VI, Banyuls/Mer, France.

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http://dx.doi.org/10.1210/en.2005-1565DOI Listing
May 2006

Melatonin pathway: breaking the 'high-at-night' rule in trout retina.

Exp Eye Res 2006 Apr 11;82(4):620-7. Epub 2005 Nov 11.

Laboratoire Aragó, Université P&M Curie (UPMC) and CNRS, UMR 7628, BP44, 66651 Banyuls/Mer-Cedex, France.

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http://dx.doi.org/10.1016/j.exer.2005.08.025DOI Listing
April 2006

Expression of the Otx2 homeobox gene in the developing mammalian brain: embryonic and adult expression in the pineal gland.

J Neurochem 2006 Apr 15;97(2):556-66. Epub 2006 Mar 15.

Institute of Medical Anatomy, Panum Institute, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1471-4159.2006.03773.xDOI Listing
April 2006

Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina.

Prog Retin Eye Res 2005 Jul;24(4):433-56

Department of Pharmacology, Emory University School of Medicine, 1510 Clifton Road, rm. 5107, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.preteyeres.2005.01.003DOI Listing
July 2005

A novel pineal-specific product of the oligopeptide transporter PepT1 gene: circadian expression mediated by cAMP activation of an intronic promoter.

J Biol Chem 2005 Apr 31;280(17):16851-60. Epub 2005 Jan 31.

Section on Neuroendocrinology, Laboratory of Developmental Neurobiology, NICHD, National Institutes of Health, Bethesda, Maryland 20892-4480, USA.

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http://dx.doi.org/10.1074/jbc.M414587200DOI Listing
April 2005

Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.

J Biol Chem 2005 Mar 4;280(11):10462-7. Epub 2005 Jan 4.

Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1074/jbc.M412283200DOI Listing
March 2005

Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression.

J Biol Chem 2005 Jan 25;280(1):677-84. Epub 2004 Oct 25.

Section on Neuroendocrinology, Laboratory of Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1074/jbc.M408438200DOI Listing
January 2005

Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205.

Proc Natl Acad Sci U S A 2005 Jan 11;102(4):1222-7. Epub 2005 Jan 11.

Section on Neuroendocrinology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-4480, USA.

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http://dx.doi.org/10.1073/pnas.0406871102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC544185PMC
January 2005

Mitogen-activated protein kinase phosphatase-1 (MKP-1): >100-fold nocturnal and norepinephrine-induced changes in the rat pineal gland.

FEBS Lett 2004 Nov;577(1-2):220-6

Department of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta., Canada T6G 2H7.

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http://dx.doi.org/10.1016/j.febslet.2004.09.083DOI Listing
November 2004

The 2004 Aschoff/Pittendrigh lecture: Theory of the origin of the pineal gland--a tale of conflict and resolution.

Authors:
David C Klein

J Biol Rhythms 2004 Aug;19(4):264-79

Section on Neuroendocrinology, Laboratory of Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-4480, USA.

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http://dx.doi.org/10.1177/0748730404267340DOI Listing
August 2004

Evolution of cell-cell signaling in animals: did late horizontal gene transfer from bacteria have a role?

Trends Genet 2004 Jul;20(7):292-9

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016895250400133
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http://dx.doi.org/10.1016/j.tig.2004.05.007DOI Listing
July 2004

Zebrafish serotonin-N-acetyltransferase-2 gene regulation: pineal-restrictive downstream module contains a functional E-box and three photoreceptor conserved elements.

Mol Endocrinol 2004 May 26;18(5):1210-21. Epub 2004 Feb 26.

Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.

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http://dx.doi.org/10.1210/me.2003-0439DOI Listing
May 2004

Cellular stabilization of the melatonin rhythm enzyme induced by nonhydrolyzable phosphonate incorporation.

Nat Struct Biol 2003 Dec 26;10(12):1054-7. Epub 2003 Oct 26.

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/nsb1005DOI Listing
December 2003

Temporal-spatial characterization of chicken clock genes: circadian expression in retina, pineal gland, and peripheral tissues.

J Neurochem 2003 May;85(4):851-60

Division of Cardiology, Department of Medicine, Glenfield General Hospital, Clinical Sciences Wing, University of Leicester, Leicester LE3 9QP, UK.

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http://dx.doi.org/10.1046/j.1471-4159.2003.01723.xDOI Listing
May 2003

Pineal-specific expression of green fluorescent protein under the control of the serotonin-N-acetyltransferase gene regulatory regions in transgenic zebrafish.

Dev Dyn 2002 Nov;225(3):241-9

Department of Zoology, George S Wise Faculty of Sciences, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1002/dvdy.10152DOI Listing
November 2002

Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87).

J Clin Endocrinol Metab 2002 Oct;87(10):4699-706

Section on Neuroendocrinology, Laboratory of Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-4480, USA.

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http://dx.doi.org/10.1210/jc.2002-020683DOI Listing
October 2002

Signal transduction and regulation of melatonin synthesis in bovine pinealocytes: impact of adrenergic, peptidergic and cholinergic stimuli.

Cell Tissue Res 2002 Sep 14;309(3):417-28. Epub 2002 Aug 14.

Dr. Senckenbergische Anatomie, Institut für Anatomie II, Johann Wolfgang Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.

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http://dx.doi.org/10.1007/s00441-002-0588-xDOI Listing
September 2002

Control of melatonin synthesis in the mammalian pineal gland: the critical role of serotonin acetylation.

Cell Tissue Res 2002 Jul 29;309(1):127-37. Epub 2002 May 29.

Section on Neuroendocrinology, Laboratory of Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-4480, USA.

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http://dx.doi.org/10.1007/s00441-002-0579-yDOI Listing
July 2002

Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase.

Invest Ophthalmol Vis Sci 2002 Feb;43(2):564-72

Department of Pharmacology, Emory University School of Medicine, Atlanta, Georgia 30322-3090, USA.

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February 2002