David Bryder

David Bryder

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David Bryder

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Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis.

Stem Cell Reports 2020 Feb 16;14(2):285-299. Epub 2020 Jan 16.

Department of Pediatrics, Section of Hematology/Oncology/BMT University of Colorado, Denver/Anschutz Medical Campus, Aurora, CO 80045, USA; Department of Pharmacology, University of Colorado, Denver/Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013201PMC
February 2020

Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML.

Stem Cell Reports 2019 01 27;12(1):112-121. Epub 2018 Dec 27.

Division of Molecular Hematology, Lund Stem Cell Center, Lund University, BMC B12, Sölvegatan 17, 22184 Lund, Sweden; Sahlgrenska Cancer Center, Gothenburg University, 40530 Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335588PMC
January 2019

Rapid and efficient induction of functional astrocytes from human pluripotent stem cells.

Nat Methods 2018 09 20;15(9):693-696. Epub 2018 Aug 20.

Stem Cells, Aging and Neurodegeneration Group, Faculty of Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1038/s41592-018-0103-2DOI Listing
September 2018

Immunoediting is not a primary transformation event in a murine model of MLL-ENL AML.

Life Sci Alliance 2018 Aug 10;1(4):e201800079. Epub 2018 Jul 10.

Division of Molecular Hematology, Department of Laboratory Medicine, Lund University, Lund, Sweden.

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http://www.life-science-alliance.org/lookup/doi/10.26508/lsa
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http://dx.doi.org/10.26508/lsa.201800079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238415PMC
August 2018

Immunophenotypic Identification of Early Myeloerythroid Development.

Methods Mol Biol 2018 ;1678:301-319

Division of Molecular Hematology, Institution for Laboratory Medicine, Lund University, Klinikgatan 26, 221 84, Lund, Sweden.

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http://link.springer.com/10.1007/978-1-4939-7346-0_13
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http://dx.doi.org/10.1007/978-1-4939-7346-0_13DOI Listing
June 2018

SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies.

Leukemia 2018 05 25;32(5):1106-1115. Epub 2018 Feb 25.

Department of Hematology, University Hospital Linköping, Linköping, Sweden.

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http://dx.doi.org/10.1038/s41375-018-0074-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940635PMC
May 2018

The slippery slope of hematopoietic stem cell aging.

Exp Hematol 2017 12 21;56:1-6. Epub 2017 Sep 21.

Medical Faculty, Institution for Laboratory Medicine, Division of Molecular Hematology, Lund University, Lund, Sweden; StemTherapy, Lund University, Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.09.008DOI Listing
December 2017

Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor.

Cell Rep 2017 Nov;21(8):2251-2263

Lund University, Medical Faculty, Institution for Laboratory Medicine, Division of Molecular Hematology, Klinikgatan 26, BMC B12, 221 84 Lund, Sweden; StemTherapy, Lund University, 221 84 Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714592PMC
November 2017

ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.

Blood 2017 08 14;130(5):619-624. Epub 2017 Jun 14.

Program in Cellular and Molecular Medicine, Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA.

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http://dx.doi.org/10.1182/blood-2016-09-738591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542850PMC
August 2017

Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate.

Nat Commun 2017 02 22;8:14533. Epub 2017 Feb 22.

Lund University, Medical Faculty, Institution for Laboratory Medicine, Division of Molecular Hematology, Klinikgatan 26, BMC B12, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1038/ncomms14533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322498PMC
February 2017

Molecular mechanisms underlying lineage bias in aging hematopoiesis.

Semin Hematol 2017 01 20;54(1):4-11. Epub 2016 Nov 20.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pathology, NYU School of Medicine, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2016.11.002DOI Listing
January 2017

Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level.

Immunity 2016 08;45(2):346-57

Division of Molecular Hematology, Department of Laboratory Medicine, Lund Stem Cell Center, Faculty of Medicine, Lund University, Lund 22242, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613163028
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http://dx.doi.org/10.1016/j.immuni.2016.07.014DOI Listing
August 2016

Hematopoiesis at single-cell resolution.

Authors:
David Bryder

Blood 2016 08;128(8):1025-6

LUND UNIVERSITY.

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http://dx.doi.org/10.1182/blood-2016-07-726497DOI Listing
August 2016

Potential Pitfalls of the Mx1-Cre System: Implications for Experimental Modeling of Normal and Malignant Hematopoiesis.

Stem Cell Reports 2016 07 30;7(1):11-8. Epub 2016 Jun 30.

Division of Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund 22184, Sweden; Division of Molecular Hematology, Lund Stem Cell Center, Lund University, Lund 22184, Sweden; Department of Hematology, Skanes University Hospital, Lund 22184, Sweden; Department of Hematology, Linköping University Hospital, Linköping 58183, Sweden; Department of Clinical and Experimental Medicine, Linköping University, Linköping 58183, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945592PMC
July 2016

Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis.

Cell Rep 2016 Mar 17;14(12):2809-18. Epub 2016 Mar 17.

Division of Molecular Hematology, Department of Laboratory Medicine, Medical Faculty, Lund University, Klinikgatan 26, BMC B12, 22184 Lund, Sweden; Hemato-Linné, Lund University, 22184 Lund, Sweden; StemTherapy, Lund University, 22184 Lund, Sweden; Lund Stem Cell Center, Lund University, 22184 Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819906PMC
March 2016

SCExV: a webtool for the analysis and visualisation of single cell qRT-PCR data.

BMC Bioinformatics 2015 Oct 5;16:320. Epub 2015 Oct 5.

Division of Molecular Hematology, BMC B12, Lund University, Sölvegatan 19, Lund, 22184, Sweden.

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http://dx.doi.org/10.1186/s12859-015-0757-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595270PMC
October 2015

Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification.

Exp Hematol 2015 Sep 29;43(9):812-7.e1. Epub 2015 May 29.

Medical Faculty, Division of Molecular Hematology, Institution for Laboratory Medicine, Lund University, Lund, Sweden; Lund Stem Cell Center, Lund, Sweden.

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http://dx.doi.org/10.1016/j.exphem.2015.05.003DOI Listing
September 2015

Concise review: hematopoietic stem cell aging and the prospects for rejuvenation.

Stem Cells Transl Med 2015 Feb 29;4(2):186-94. Epub 2014 Dec 29.

Immunology Section, Institution for Experimental Medical Science, Lund University, Lund, Sweden; Department of Pediatric Oncology/Hematology, Skåne University Hospital, Lund, Sweden

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http://dx.doi.org/10.5966/sctm.2014-0132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303356PMC
February 2015

HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia.

Blood 2014 Dec 29;124(24):3597-607. Epub 2014 Sep 29.

Department of Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund, Sweden; Department of Hematology, Skanes University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2014-04-567065DOI Listing
December 2014

Hematopoietic stem cells are intrinsically protected against MLL-ENL-mediated transformation.

Cell Rep 2014 Nov 13;9(4):1246-55. Epub 2014 Nov 13.

Immunology Section, Department of Experimental Medical Science, Biomedical Center D14, Lund University, Klinikgatan 32, 221 84 Lund, Sweden; Lund Stem Cell Center, Biomedical Center B10, Klinikgatan 26, 221 84 Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.036DOI Listing
November 2014

Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9.

Cell Stem Cell 2014 Nov 6;15(5):643-52. Epub 2014 Nov 6.

Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Broad Institute, Cambridge, MA 02142, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269831PMC
November 2014

Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects.

Stem Cells 2014 May;32(5):1173-82

Medical Faculty, Institution for Experimental Medical Science, Immunology Section, Lund Stem Cell Center, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1002/stem.1630DOI Listing
May 2014

Induced hematopoietic stem cells: unlocking restrictions in lineage potential and self-renewal.

Cell Stem Cell 2014 May;14(5):555-6

Immunology Section, Institution for Experimental Medical Science, Lund University, Sölvegatan 17, BMC D14, 221 84, Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.04.008DOI Listing
May 2014

Frequency determination of rare populations by flow cytometry: a hematopoietic stem cell perspective.

Cytometry A 2013 Aug 9;83(8):721-7. Epub 2013 Jul 9.

Immunology Unit, Institution for Experimental Medical Research, Lund University, 221 84, Lund, Sweden.

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http://dx.doi.org/10.1002/cyto.a.22324DOI Listing
August 2013

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

Blood 2013 May 8;121(21):4257-64. Epub 2013 Mar 8.

Immunology Section, Lund University, Medical Faculty, Institution for Experimental Medical Science, Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2012-11-469080DOI Listing
May 2013

Dynamical modelling of haematopoiesis: an integrated view over the system in homeostasis and under perturbation.

J R Soc Interface 2013 Mar 6;10(80):20120817. Epub 2013 Mar 6.

Computational Biology and Biological Physics, Department of Astronomy and Theoretical Physics, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1098/rsif.2012.0817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565732PMC
March 2013

Reduced repression of cytokine signaling ameliorates age-induced decline in hematopoietic stem cell function.

Aging Cell 2012 Dec 27;11(6):1128-31. Epub 2012 Aug 27.

Lund University, Institution for Experimental Medical Science, Immunology section, BMC D14, Tornavägen 10, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1111/j.1474-9726.2012.00863.xDOI Listing
December 2012

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.

Blood 2012 Sep 12;120(11):2225-8. Epub 2012 Jul 12.

Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2012-05-431437DOI Listing
September 2012

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.

Blood 2011 Dec 11;118(23):6087-96. Epub 2011 Oct 11.

Molecular Medicine and Gene Therapy, Lund Strategic Center for Stem Cell Biology, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2011-08-371963DOI Listing
December 2011

The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor.

Proc Natl Acad Sci U S A 2011 Oct 4;108(42):17402-7. Epub 2011 Oct 4.

Department of Molecular Biology, University of California at San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1073/pnas.1111766108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198373PMC
October 2011

Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors.

J Exp Med 2011 Aug 18;208(8):1563-70. Epub 2011 Jul 18.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1084/jem.20110752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149225PMC
August 2011

Flow cytometry-based identification of immature myeloerythroid development.

Methods Mol Biol 2011 ;699:275-93

Department of Paediatrics, Section of Immunology/Stem Cell Center, Lund University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1007/978-1-61737-950-5_13DOI Listing
May 2011

Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging.

Cell Stem Cell 2011 May;8(5):499-510

Immunology Section, Institution for Experimental Medical Science, BMC D14, Lund University, Tornavägen 10, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1016/j.stem.2011.03.009DOI Listing
May 2011

Load and lock: the molecular mechanisms of B-lymphocyte commitment.

Immunol Rev 2010 Nov;238(1):47-62

Experimental Hematopoiesis Unit, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.

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http://dx.doi.org/10.1111/j.1600-065X.2010.00950.xDOI Listing
November 2010

Shaping up a lineage--lessons from B lymphopoesis.

Curr Opin Immunol 2010 Apr 6;22(2):148-53. Epub 2010 Mar 6.

Department of Immunology, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1016/j.coi.2010.02.001DOI Listing
April 2010

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.

Proc Natl Acad Sci U S A 2010 Mar 18;107(12):5465-70. Epub 2010 Mar 18.

Immune Disease Institute, Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1000834107
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http://dx.doi.org/10.1073/pnas.1000834107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851806PMC
March 2010

Niche recycling through division-independent egress of hematopoietic stem cells.

J Exp Med 2009 Nov 2;206(12):2837-50. Epub 2009 Nov 2.

Institute of Stem Cell Biology and Regenerative Medicine Stanford University School of Medicine Stanford, CA 94305, USA.

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http://dx.doi.org/10.1084/jem.20090778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806613PMC
November 2009

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells.

Blood 2008 Aug 21;112(4):1048-55. Epub 2008 May 21.

Department for Biomedicine and Surgery, Linköping University, Linköping, Sweden.

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http://dx.doi.org/10.1182/blood-2007-11-125385DOI Listing
August 2008

Deciphering developmental stages of adult myelopoiesis.

Cell Cycle 2008 Mar;7(6):706-13

Institution for Experimental Medical Science, Immunology Section, Lund University, Lund, Sweden

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http://dx.doi.org/10.4161/cc.7.6.5565DOI Listing
March 2008

Kit regulates maintenance of quiescent hematopoietic stem cells.

J Immunol 2008 Feb;180(4):2045-53

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

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http://dx.doi.org/10.4049/jimmunol.180.4.2045DOI Listing
February 2008

Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development.

Stem Cells 2007 Nov 2;25(11):2809-19. Epub 2007 Aug 2.

Molecular Medicine and Gene Therapy, Institute of Laboratory Medicine, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University Hospital, Lund, Sweden.

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http://doi.wiley.com/10.1634/stemcells.2006-0602
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http://dx.doi.org/10.1634/stemcells.2006-0602DOI Listing
November 2007

Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

Cell Cycle 2007 Oct 18;6(19):2371-6. Epub 2007 Jul 18.

Department of Pathology, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.4161/cc.6.19.4759DOI Listing
October 2007

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

Cell Stem Cell 2007 Oct;1(4):428-42

Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, BMC I13, 221 84 Lund, Sweden; Immunology Unit, Institution for Experimental Medical Science, Lund University, BMC I13, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1016/j.stem.2007.07.005DOI Listing
October 2007

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.

Nature 2007 Jun;447(7145):725-9

Department of Pathology, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/nature05862DOI Listing
June 2007

Hematopoietic stem cell aging: mechanism and consequence.

Exp Gerontol 2007 May 31;42(5):385-90. Epub 2007 Jan 31.

Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.exger.2006.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892213PMC
May 2007

The Cxcl12, periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells.

J Biol Chem 2007 May 20;282(19):14454-62. Epub 2007 Mar 20.

Department for Hematopoetic Stem Cell Biology, Lund Stemcell Center, Lund University BMC B12, S-221 84 Lund, Sweden.

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http://dx.doi.org/10.1074/jbc.M610263200DOI Listing
May 2007

Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR.

Proc Natl Acad Sci U S A 2006 Nov 10;103(47):17807-12. Epub 2006 Nov 10.

Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.0608512103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693828PMC
November 2006

Hematopoietic stem cells: the paradigmatic tissue-specific stem cell.

Am J Pathol 2006 Aug;169(2):338-46

Stanford University School of Medicine, B257 Beckman Center, Stanford, CA 94305-5323, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698791PMC
http://dx.doi.org/10.2353/ajpath.2006.060312DOI Listing
August 2006

Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic stem cell property.

J Immunol 2006 Jul;177(1):201-8

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

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http://dx.doi.org/10.4049/jimmunol.177.1.201DOI Listing
July 2006

Rapid lymphocyte reconstitution of unconditioned immunodeficient mice with non-self-renewing multipotent hematopoietic progenitors.

Cell Cycle 2006 Jun 1;5(11):1135-9. Epub 2006 Jun 1.

Institute of Cancer and Stem Cell Biology and Medicine, Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4507427PMC
http://dx.doi.org/10.4161/cc.5.11.2772DOI Listing
June 2006

Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.

J Exp Med 2006 Jan 27;203(1):73-85. Epub 2005 Dec 27.

Department of Pathology, Institute of Cancer and Stem Cell Biology and Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://www.jem.org/lookup/doi/10.1084/jem.20051714
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http://dx.doi.org/10.1084/jem.20051714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118067PMC
January 2006

Cell intrinsic alterations underlie hematopoietic stem cell aging.

Proc Natl Acad Sci U S A 2005 Jun 20;102(26):9194-9. Epub 2005 Jun 20.

Department of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.0503280102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1153718PMC
June 2005

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

Blood 2005 Apr 30;105(7):2717-23. Epub 2004 Nov 30.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, BMC B10, Klinikgatan 26, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2004-06-2159DOI Listing
April 2005

Deficiency of oncoretrovirally transduced hematopoietic stem cells and correction through ex vivo expansion.

J Gene Med 2005 Feb;7(2):137-44

Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Hematopoietic Stem Cell Laboratory, Lund University, BMC B10, 221 84, Lund, Sweden.

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http://dx.doi.org/10.1002/jgm.658DOI Listing
February 2005

IFN-gamma negatively modulates self-renewal of repopulating human hemopoietic stem cells.

J Immunol 2005 Jan;174(2):752-7

Hemopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

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http://dx.doi.org/10.4049/jimmunol.174.2.752DOI Listing
January 2005

Deceptive multilineage reconstitution analysis of mice transplanted with hemopoietic stem cells, and implications for assessment of stem cell numbers and lineage potentials.

J Immunol 2004 Feb;172(3):1548-52

Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, Lund, Sweden.

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http://dx.doi.org/10.4049/jimmunol.172.3.1548DOI Listing
February 2004

Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.

J Exp Med 2003 Nov 10;198(10):1495-506. Epub 2003 Nov 10.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University Hospital, BMC 10, Klinikgatan 26, 221-84 Lund, Sweden.

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http://dx.doi.org/10.1084/jem.20031152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194121PMC
November 2003

Human reconstituting hematopoietic stem cells up-regulate Fas expression upon active cell cycling but remain resistant to Fas-induced suppression.

Blood 2003 Jul 13;102(1):118-26. Epub 2003 Mar 13.

Hematopoietic Stem Cell Laboratory, Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, BMC B10, Lund University Hospital, 22184 Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2002-07-2286DOI Listing
July 2003

Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool.

Immunity 2002 Oct;17(4):463-72

Department of Stem Cell Biology, Institute of Laboratory Medicine, University Hospital of Lund, BMC, B12, Klinikgatan 26, 221-84 Lund, Sweden.

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http://dx.doi.org/10.1016/s1074-7613(02)00419-3DOI Listing
October 2002