Publications by authors named "David Botstein"

143 Publications

Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases.

Authors:
David Botstein

Genetics 2020 Oct;216(2):261-262

Calico Life Sciences LLC, South San Francisco, California 94080 and Princeton University, Princeton, New Jersey 08544

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October 2020

A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1.

PLoS One 2020 29;15(5):e0233779. Epub 2020 May 29.

Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America.

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September 2020

Minor Isozymes Tailor Yeast Metabolism to Carbon Availability.

mSystems 2019 Jan-Feb;4(1). Epub 2019 Feb 26.

Department of Chemistry, Princeton University, Princeton, New Jersey, USA.

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February 2019

Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase.

ACS Chem Biol 2018 10 4;13(10):3011-3020. Epub 2018 Oct 4.

Lewis Sigler Institute for Integrative Genomics , Princeton University , Princeton , New Jersey 08544 , United States.

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October 2018

The future of humans as model organisms.

Science 2018 08;361(6402):552-553

The Institute for Translational Medicine and Therapeutics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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August 2018

Systems-level analysis of mechanisms regulating yeast metabolic flux.

Science 2016 10 27;354(6311). Epub 2016 Oct 27.

Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA. Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.

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October 2016

Extrachromosomal circular DNA is common in yeast.

Proc Natl Acad Sci U S A 2015 Jun 2;112(24):E3114-22. Epub 2015 Jun 2.

Department of Biology, University of Copenhagen, DK-2200 Copenhagen N, Denmark;

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June 2015

Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporter.

Proc Natl Acad Sci U S A 2015 May 27;112(19):6116-21. Epub 2015 Apr 27.

Lewis-Sigler Institute for Integrative Genomics and Departments of Molecular Biology and

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May 2015

Lasker∼Koshland to genetics pioneer.

Authors:
David Botstein

Cell 2014 Sep;158(6):1230-1232

Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA. Electronic address:

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September 2014

Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiae.

Nucleic Acids Res 2014 Apr 20;42(6):e48. Epub 2014 Jan 20.

The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA, Amyris, Inc., Emeryville, CA 94608, USA, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA and Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.

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April 2014

Rapid synthesis and screening of chemically activated transcription factors with GFP-based reporters.

J Vis Exp 2013 Nov 26(81):e51153. Epub 2013 Nov 26.

The Lewis-Sigler Institute for Integrative Genomics, Princeton University.

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November 2013

Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.

Proc Natl Acad Sci U S A 2013 Nov 28;110(46):E4393-402. Epub 2013 Oct 28.

Lewis-Sigler Institute for Integrative Genomics and Department of Molecular Biology, Princeton University, Princeton, NJ 08544.

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November 2013

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations.

Nature 2013 Aug 21;500(7464):571-4. Epub 2013 Jul 21.

Lewis-Sigler Institute for Integrative Genomics and Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.

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August 2013

Phylogenetic portrait of the Saccharomyces cerevisiae functional genome.

G3 (Bethesda) 2013 Aug 7;3(8):1335-40. Epub 2013 Aug 7.

The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.

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August 2013

Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case.

G3 (Bethesda) 2013 04 9;3(4):733-740. Epub 2013 Apr 9.

Department of Biology, Santa Clara University, Santa Clara, California 95053

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April 2013

Automating the construction of gene ontologies.

Nat Biotechnol 2013 Jan;31(1):34-5

Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA.

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January 2013

Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast.

Nucleic Acids Res 2013 Feb 28;41(4):e57. Epub 2012 Dec 28.

The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.

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February 2013

TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae.

Mol Biol Cell 2013 Jan 21;24(2):115-28. Epub 2012 Nov 21.

Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.

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January 2013

Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression.

Mol Biol Cell 2013 Jan 7;24(2):157-68. Epub 2012 Nov 7.

Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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January 2013

Why we need more basic biology research, not less.

Authors:
David Botstein

Mol Biol Cell 2012 Nov;23(21):4160-1

Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.

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November 2012

Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway.

Mol Biol Cell 2012 Aug 13;23(15):2993-3007. Epub 2012 Jun 13.

The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.

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August 2012

Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathway.

Mol Biol Cell 2012 Aug 13;23(15):3008-24. Epub 2012 Jun 13.

The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.

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August 2012