Publications by authors named "David B Sattelle"

100Publications

Turning a Drug Target into a Drug Candidate: A New Paradigm for Neurological Drug Discovery?

Bioessays 2020 Aug 9:e2000011. Epub 2020 Aug 9.

UCL Respiratory, University College London, 5 University Street, London, WC1E 6JF, UK.

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http://dx.doi.org/10.1002/bies.202000011DOI Listing
August 2020

Anthelmintic drug discovery: target identification, screening methods and the role of open science.

Beilstein J Org Chem 2020 2;16:1203-1224. Epub 2020 Jun 2.

Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.3762/bjoc.16.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277699PMC
June 2020

Whipworm and roundworm infections.

Nat Rev Dis Primers 2020 05 28;6(1):44. Epub 2020 May 28.

Institute of Infection and Immunity, St George's University of London, London, UK.

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http://dx.doi.org/10.1038/s41572-020-0171-3DOI Listing
May 2020

Actions on mammalian and insect nicotinic acetylcholine receptors of harmonine-containing alkaloid extracts from the harlequin ladybird Harmonia axyridis.

Pestic Biochem Physiol 2020 Jun 6;166:104561. Epub 2020 Mar 6.

School of Life Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.pestbp.2020.104561DOI Listing
June 2020

Neonicotinoid Insecticides: Molecular Targets, Resistance, and Toxicity.

Annu Rev Pharmacol Toxicol 2020 01;60:241-255

Centre for Respiratory Biology, UCL Respiratory, University College London, London WC1E 6JF, United Kingdom; email:

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http://dx.doi.org/10.1146/annurev-pharmtox-010818-021747DOI Listing
January 2020

Calcium signalling in mammalian cell lines expressing wild type and mutant human α1-Antitrypsin.

Sci Rep 2019 11 21;9(1):17293. Epub 2019 Nov 21.

Centre for Respiratory Biology, UCL Respiratory, Rayne Building, University College London, 5 University Street, London, WC1E 6JF, UK.

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http://dx.doi.org/10.1038/s41598-019-53535-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872872PMC
November 2019

Combined effects of mutations in loop C and the loop D-E-G triangle on neonicotinoid interactions with Drosophila Dα1/chicken β2 hybrid nAChRs.

Pestic Biochem Physiol 2018 Oct 27;151:47-52. Epub 2018 Mar 27.

Department of Applied Biological Chemistry, Faculty of Agriculture, Kindai University, 3327-204 Nakamachi, Nara 631-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.pestbp.2018.03.008DOI Listing
October 2018

Editorial overview: Insect neuroreceptors and ion channels - roles as targets in the control of insect vectors and pests.

Curr Opin Insect Sci 2018 12 15;30:iii-v. Epub 2018 Oct 15.

Kindai University, Japan.

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http://dx.doi.org/10.1016/j.cois.2018.10.002DOI Listing
December 2018

Insect toxins - selective pharmacological tools and drug/chemical leads.

Curr Opin Insect Sci 2018 12 9;30:93-98. Epub 2018 Oct 9.

Centre for Respiratory Biology, UCL Respiratory, University College London, Rayne Building, 5 University Street, London WC1E 6JF, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cois.2018.10.001DOI Listing
December 2018

Improved reference genome of Aedes aegypti informs arbovirus vector control.

Nature 2018 11 14;563(7732):501-507. Epub 2018 Nov 14.

Laboratory of Neurogenetics and Behavior, The Rockefeller University, New York, NY, USA.

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http://www.nature.com/articles/s41586-018-0692-z
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http://dx.doi.org/10.1038/s41586-018-0692-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421076PMC
November 2018

The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease.

Int J Parasitol Drugs Drug Resist 2018 08 4;8(2):350-360. Epub 2018 Jun 4.

Neurosystems Section, Faculty of Life Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK; Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, Rayne Building, 5 University Street, London WC1E 6JF, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039357PMC
August 2018

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes.

Int J Parasitol Drugs Drug Resist 2018 04 2;8(1):8-21. Epub 2017 Dec 2.

Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2017.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734697PMC
April 2018

An L319F mutation in transmembrane region 3 (TM3) selectively reduces sensitivity to okaramine B of the Bombyx mori l-glutamate-gated chloride channel.

Biosci Biotechnol Biochem 2017 Oct 21;81(10):1861-1867. Epub 2017 Aug 21.

a Faculty of Agriculture, Department of Applied Biological Chemistry , Kindai University , Nara , Japan.

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http://dx.doi.org/10.1080/09168451.2017.1359487DOI Listing
October 2017

Mechanisms of Action, Resistance and Toxicity of Insecticides Targeting GABA Receptors.

Curr Med Chem 2017 ;24(27):2935-2945

Department of Applied Biological Chemistry, Faculty of Agriculture, Kindai University, 3327-204 Nakamachi, Nara 631-8505. Japan.

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http://www.eurekaselect.com/153125/article
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http://dx.doi.org/10.2174/0929867324666170613075736DOI Listing
October 2017

Modes of Action, Resistance and Toxicity of Insecticides Targeting Nicotinic Acetylcholine Receptors.

Curr Med Chem 2017 ;24(27):2925-2934

Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, Rayne Building, 5 University Street London WC1E 6JF. United Kingdom.

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http://dx.doi.org/10.2174/0929867324666170206142019DOI Listing
October 2017

Tick Genome Assembled: New Opportunities for Research on Tick-Host-Pathogen Interactions.

Front Cell Infect Microbiol 2016 15;6:103. Epub 2016 Sep 15.

Department of Entomology, Purdue University West Lafayette, IN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024572PMC
http://dx.doi.org/10.3389/fcimb.2016.00103DOI Listing
September 2017

Okaramine insecticidal alkaloids show similar activity on both exon 3c and exon 3b variants of glutamate-gated chloride channels of the larval silkworm, Bombyx mori.

Neurotoxicology 2017 May 3;60:240-244. Epub 2016 May 3.

Department of Applied Biological Chemistry, Faculty of Agriculture, Kindai University, 3327-204 Nakamachi, Nara 631-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2016.05.002DOI Listing
May 2017

Genomic insights into the Ixodes scapularis tick vector of Lyme disease.

Authors:
Monika Gulia-Nuss Andrew B Nuss Jason M Meyer Daniel E Sonenshine R Michael Roe Robert M Waterhouse David B Sattelle José de la Fuente Jose M Ribeiro Karine Megy Jyothi Thimmapuram Jason R Miller Brian P Walenz Sergey Koren Jessica B Hostetler Mathangi Thiagarajan Vinita S Joardar Linda I Hannick Shelby Bidwell Martin P Hammond Sarah Young Qiandong Zeng Jenica L Abrudan Francisca C Almeida Nieves Ayllón Ketaki Bhide Brooke W Bissinger Elena Bonzon-Kulichenko Steven D Buckingham Daniel R Caffrey Melissa J Caimano Vincent Croset Timothy Driscoll Don Gilbert Joseph J Gillespie Gloria I Giraldo-Calderón Jeffrey M Grabowski David Jiang Sayed M S Khalil Donghun Kim Katherine M Kocan Juraj Koči Richard J Kuhn Timothy J Kurtti Kristin Lees Emma G Lang Ryan C Kennedy Hyeogsun Kwon Rushika Perera Yumin Qi Justin D Radolf Joyce M Sakamoto Alejandro Sánchez-Gracia Maiara S Severo Neal Silverman Ladislav Šimo Marta Tojo Cristian Tornador Janice P Van Zee Jesús Vázquez Filipe G Vieira Margarita Villar Adam R Wespiser Yunlong Yang Jiwei Zhu Peter Arensburger Patricia V Pietrantonio Stephen C Barker Renfu Shao Evgeny M Zdobnov Frank Hauser Cornelis J P Grimmelikhuijzen Yoonseong Park Julio Rozas Richard Benton Joao H F Pedra David R Nelson Maria F Unger Jose M C Tubio Zhijian Tu Hugh M Robertson Martin Shumway Granger Sutton Jennifer R Wortman Daniel Lawson Stephen K Wikel Vishvanath M Nene Claire M Fraser Frank H Collins Bruce Birren Karen E Nelson Elisabet Caler Catherine A Hill

Nat Commun 2016 Feb 9;7:10507. Epub 2016 Feb 9.

Department of Entomology, Purdue University, West Lafayette, Indiana 47907, USA.

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http://dx.doi.org/10.1038/ncomms10507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748124PMC
February 2016

Probing new components (loop G and the α-α interface) of neonicotinoid binding sites on nicotinic acetylcholine receptors.

Pestic Biochem Physiol 2015 Jun 28;121:47-52. Epub 2015 Feb 28.

Department of Applied Biological Chemistry, Faculty of Agriculture, Kinki University, 3327-204 Nakamachi, Nara 631-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.pestbp.2015.02.011DOI Listing
June 2015

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics.

Int J Parasitol Drugs Drug Resist 2014 Dec 30;4(3):226-32. Epub 2014 Oct 30.

Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Cruciform Building, Gower Street, London WC1E 6BT, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S22113207140003
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http://dx.doi.org/10.1016/j.ijpddr.2014.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266775PMC
December 2014

Studies on an acetylcholine binding protein identify a basic residue in loop G on the β1 strand as a new structural determinant of neonicotinoid actions.

Mol Pharmacol 2014 Dec 29;86(6):736-46. Epub 2014 Sep 29.

Department of Applied Biological Chemistry, Faculty of Agriculture, Kinki University, Nara, Japan (M.I., Ta.O., T.A., M.M., K.M.); Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, Japan (To.O.); Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Kita-ku, Okayama, Japan (A.Y.); and The Wolfson Institute for Biomedical Research, Department of Medicine, University College London, London, United Kingdom (D.B.S.)

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http://dx.doi.org/10.1124/mol.114.094698DOI Listing
December 2014

An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro.

BMC Infect Dis 2014 Sep 27;14:520. Epub 2014 Sep 27.

Faculty of Life Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1186/1471-2334-14-520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261559PMC
September 2014

Exon 3 splicing and mutagenesis identify residues influencing cell surface density of heterologously expressed silkworm (Bombyx mori) glutamate-gated chloride channels.

Mol Pharmacol 2014 Dec 26;86(6):686-95. Epub 2014 Sep 26.

Department of Applied Biological Chemistry, Faculty of Agriculture, Kinki University, Nakamachi Nara, Japan (S.F., M.I., K.M.); Graduate School of Life Science, University of Hyogo, Koto, Kamigori-cho, Ako-gun, Hyogo, Japan (Y.N.); Graduate School of Agriculture, Kyoto University, Sakyo-Ku, Kyoto, Japan (M.A.); Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, United Kingdom (A.K.J.); and Department of Medicine, Wolfson Institute for Biomedical Research, University College London, London, United Kingdom (D.B.S.)

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http://dx.doi.org/10.1124/mol.114.095869DOI Listing
December 2014

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.

PLoS One 2014 31;9(7):e102985. Epub 2014 Jul 31.

Department of Genetics, University of Cambridge, Cambridge, United Kingdom; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102985PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117641PMC
October 2015

A single amino acid polymorphism in the Drosophila melanogaster Dα1 (ALS) subunit enhances neonicotinoid efficacy at Dα1-chicken β2 hybrid nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes.

Biosci Biotechnol Biochem 2014 30;78(4):543-9. Epub 2014 May 30.

a Faculty of Agriculture, Department of Applied Biological Chemistry , Kinki University , Nara , Japan.

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http://dx.doi.org/10.1080/09168451.2014.891928DOI Listing
August 2015

Functional characterisation of a nicotinic acetylcholine receptor α subunit from the brown dog tick, Rhipicephalus sanguineus.

Int J Parasitol 2014 Jan 1;44(1):75-81. Epub 2013 Dec 1.

Institute of Biological and Environmental Sciences, University of Aberdeen, Tillydrone Ave, Aberdeen AB24 2TZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijpara.2013.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029082PMC
January 2014

Dr. Kathleen Drew-Baker, "Mother of the Sea", a Manchester scientist celebrated each year for half a century in Japan.

Bioessays 2013 Sep;35(9):838-9

Faculty of Life Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/bies.201300061DOI Listing
September 2013

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.

J Neurochem 2012 Dec 10;123(6):911-8. Epub 2012 Oct 10.

Department of Infectious Diseases and Center for Tropical & Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.

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http://dx.doi.org/10.1111/jnc.12013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549563PMC
December 2012

Invertebrate models of spinal muscular atrophy: insights into mechanisms and potential therapeutics.

Bioessays 2011 Dec 18;33(12):956-65. Epub 2011 Oct 18.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/bies.201100082DOI Listing
December 2011

A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.

J Biol Chem 2011 Jan 21;286(4):2550-8. Epub 2010 Oct 21.

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, United Kingdom.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.177238
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http://dx.doi.org/10.1074/jbc.M110.177238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024750PMC
January 2011

Diversity of insect nicotinic acetylcholine receptor subunits.

Adv Exp Med Biol 2010 ;683:25-43

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.

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http://dx.doi.org/10.1007/978-1-4419-6445-8_3DOI Listing
September 2010

Proteins interacting with nicotinic acetylcholine receptors: expanding functional and therapeutic horizons.

Trends Pharmacol Sci 2010 Oct 30;31(10):455-62. Epub 2010 Jul 30.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S01656147100012
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http://dx.doi.org/10.1016/j.tips.2010.07.001DOI Listing
October 2010

Functional and evolutionary insights from the genomes of three parasitoid Nasonia species.

Authors:
John H Werren Stephen Richards Christopher A Desjardins Oliver Niehuis Jürgen Gadau John K Colbourne John H Werren Stephen Richards Christopher A Desjardins Oliver Niehuis Jürgen Gadau John K Colbourne Leo W Beukeboom Claude Desplan Christine G Elsik Cornelis J P Grimmelikhuijzen Paul Kitts Jeremy A Lynch Terence Murphy Deodoro C S G Oliveira Christopher D Smith Louis van de Zande Kim C Worley Evgeny M Zdobnov Maarten Aerts Stefan Albert Victor H Anaya Juan M Anzola Angel R Barchuk Susanta K Behura Agata N Bera May R Berenbaum Rinaldo C Bertossa Márcia M G Bitondi Seth R Bordenstein Peer Bork Erich Bornberg-Bauer Marleen Brunain Giuseppe Cazzamali Lesley Chaboub Joseph Chacko Dean Chavez Christopher P Childers Jeong-Hyeon Choi Michael E Clark Charles Claudianos Rochelle A Clinton Andrew G Cree Alexandre S Cristino Phat M Dang Alistair C Darby Dirk C de Graaf Bart Devreese Huyen H Dinh Rachel Edwards Navin Elango Eran Elhaik Olga Ermolaeva Jay D Evans Sylvain Foret Gerald R Fowler Daniel Gerlach Joshua D Gibson Donald G Gilbert Dan Graur Stefan Gründer Darren E Hagen Yi Han Frank Hauser Da Hultmark Henry C Hunter Gregory D D Hurst Shalini N Jhangian Huaiyang Jiang Reed M Johnson Andrew K Jones Thomas Junier Tatsuhiko Kadowaki Albert Kamping Yuri Kapustin Bobak Kechavarzi Jaebum Kim Jay Kim Boris Kiryutin Tosca Koevoets Christie L Kovar Evgenia V Kriventseva Robert Kucharski Heewook Lee Sandra L Lee Kristin Lees Lora R Lewis David W Loehlin John M Logsdon Jacqueline A Lopez Ryan J Lozado Donna Maglott Ryszard Maleszka Anoop Mayampurath Danielle J Mazur Marcella A McClure Andrew D Moore Margaret B Morgan Jean Muller Monica C Munoz-Torres Donna M Muzny Lynne V Nazareth Susanne Neupert Ngoc B Nguyen Francis M F Nunes John G Oakeshott Geoffrey O Okwuonu Bart A Pannebakker Vikas R Pejaver Zuogang Peng Stephen C Pratt Reinhard Predel Ling-Ling Pu Hilary Ranson Rhitoban Raychoudhury Andreas Rechtsteiner Justin T Reese Jeffrey G Reid Megan Riddle Hugh M Robertson Jeanne Romero-Severson Miriam Rosenberg Timothy B Sackton David B Sattelle Helge Schlüns Thomas Schmitt Martina Schneider Andreas Schüler Andrew M Schurko David M Shuker Zilá L P Simões Saurabh Sinha Zachary Smith Victor Solovyev Alexandre Souvorov Andreas Springauf Elisabeth Stafflinger Deborah E Stage Mario Stanke Yoshiaki Tanaka Arndt Telschow Carol Trent Selina Vattathil Eveline C Verhulst Lumi Viljakainen Kevin W Wanner Robert M Waterhouse James B Whitfield Timothy E Wilkes Michael Williamson Judith H Willis Florian Wolschin Stefan Wyder Takuji Yamada Soojin V Yi Courtney N Zecher Lan Zhang Richard A Gibbs

Alzheimer's disease: insights from Drosophila melanogaster models.

Trends Biochem Sci 2010 Apr 25;35(4):228-35. Epub 2009 Dec 25.

MRC Functional Genomics Unit, University of Oxford, Department of Physiology, Anatomy and Genetics, South Parks Road, Oxford OX13QX.

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http://dx.doi.org/10.1016/j.tibs.2009.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856915PMC
April 2010

Allosteric modulation by benzodiazepines of GABA-gated chloride channels of an identified insect motor neurone.

Invert Neurosci 2009 Nov 22;9(2):85-9. Epub 2009 Oct 22.

MRC Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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http://link.springer.com/10.1007/s10158-009-0091-0
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http://dx.doi.org/10.1007/s10158-009-0091-0DOI Listing
November 2009

Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits.

Invert Neurosci 2009 Nov 11;9(2):77-84. Epub 2009 Aug 11.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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http://link.springer.com/10.1007/s10158-009-0089-7
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http://dx.doi.org/10.1007/s10158-009-0089-7DOI Listing
November 2009

Fast, automated measurement of nematode swimming (thrashing) without morphometry.

BMC Neurosci 2009 Jul 20;10:84. Epub 2009 Jul 20.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK.

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http://dx.doi.org/10.1186/1471-2202-10-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729753PMC
July 2009

Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.

Biochem Pharmacol 2009 Oct 21;78(7):836-43. Epub 2009 Jun 21.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1016/j.bcp.2009.06.020DOI Listing
October 2009

Diverse actions and target-site selectivity of neonicotinoids: structural insights.

Mol Pharmacol 2009 Jul 25;76(1):1-10. Epub 2009 Mar 25.

Department of Applied Biological Chemistry, School of Agriculture, Kinki University, Nara, Japan.

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http://dx.doi.org/10.1124/mol.109.055186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701451PMC
July 2009

Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.

Pharmacol Rev 2009 Mar 16;61(1):39-61. Epub 2009 Mar 16.

Medical Research Council Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, UK, OX1 3QX.

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http://dx.doi.org/10.1124/pr.108.000562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830120PMC
March 2009

Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan.

Hum Mol Genet 2009 Jan 1;18(1):97-104. Epub 2008 Oct 1.

MRC Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1093/hmg/ddn320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644645PMC
January 2009

Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the alpha4beta2 nicotinic acetylcholine receptor.

Neuropharmacology 2009 Jan 26;56(1):264-72. Epub 2008 Aug 26.

Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University, 3327-204 Nakamachi, Nara 631-8505, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S002839080800373
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http://dx.doi.org/10.1016/j.neuropharm.2008.08.022DOI Listing
January 2009

Insect ryanodine receptors: molecular targets for novel pest control chemicals.

Invert Neurosci 2008 Sep 12;8(3):107-19. Epub 2008 Aug 12.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1007/s10158-008-0076-4DOI Listing
September 2008

Strategies for automated analysis of C. elegans locomotion.

Invert Neurosci 2008 Sep 8;8(3):121-31. Epub 2008 Aug 8.

MRC Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1007/s10158-008-0077-3DOI Listing
September 2008

The genome of the model beetle and pest Tribolium castaneum.

Authors:
Stephen Richards Richard A Gibbs George M Weinstock Susan J Brown Robin Denell Richard W Beeman Richard Gibbs Richard W Beeman Susan J Brown Gregor Bucher Markus Friedrich Cornelis J P Grimmelikhuijzen Martin Klingler Marce Lorenzen Stephen Richards Siegfried Roth Reinhard Schröder Diethard Tautz Evgeny M Zdobnov Donna Muzny Richard A Gibbs George M Weinstock Tony Attaway Stephanie Bell Christian J Buhay Mimi N Chandrabose Dean Chavez Kerstin P Clerk-Blankenburg Andrew Cree Marvin Dao Clay Davis Joseph Chacko Huyen Dinh Shannon Dugan-Rocha Gerald Fowler Toni T Garner Jeffrey Garnes Andreas Gnirke Alica Hawes Judith Hernandez Sandra Hines Michael Holder Jennifer Hume Shalini N Jhangiani Vandita Joshi Ziad Mohid Khan LaRonda Jackson Christie Kovar Andrea Kowis Sandra Lee Lora R Lewis Jon Margolis Margaret Morgan Lynne V Nazareth Ngoc Nguyen Geoffrey Okwuonu David Parker Stephen Richards San-Juana Ruiz Jireh Santibanez Joël Savard Steven E Scherer Brian Schneider Erica Sodergren Diethard Tautz Selina Vattahil Donna Villasana Courtney S White Rita Wright Yoonseong Park Richard W Beeman Jeff Lord Brenda Oppert Marce Lorenzen Susan Brown Liangjiang Wang Joël Savard Diethard Tautz Stephen Richards George Weinstock Richard A Gibbs Yue Liu Kim Worley George Weinstock Christine G Elsik Justin T Reese Eran Elhaik Giddy Landan Dan Graur Peter Arensburger Peter Atkinson Richard W Beeman Jim Beidler Susan J Brown Jeffery P Demuth Douglas W Drury Yu-Zhou Du Haruhiko Fujiwara Marce Lorenzen Vincenza Maselli Mizuko Osanai Yoonseong Park Hugh M Robertson Zhijian Tu Jian-jun Wang Suzhi Wang Stephen Richards Henry Song Lan Zhang Erica Sodergren Doreen Werner Mario Stanke Burkhard Morgenstern Victor Solovyev Peter Kosarev Garth Brown Hsiu-Chuan Chen Olga Ermolaeva Wratko Hlavina Yuri Kapustin Boris Kiryutin Paul Kitts Donna Maglott Kim Pruitt Victor Sapojnikov Alexandre Souvorov Aaron J Mackey Robert M Waterhouse Stefan Wyder Evgeny M Zdobnov Evgeny M Zdobnov Stefan Wyder Evgenia V Kriventseva Tatsuhiko Kadowaki Peer Bork Manuel Aranda Riyue Bao Anke Beermann Nicola Berns Renata Bolognesi François Bonneton Daniel Bopp Susan J Brown Gregor Bucher Thomas Butts Arnaud Chaumot Robin E Denell David E K Ferrier Markus Friedrich Cassondra M Gordon Marek Jindra Martin Klingler Que Lan H Michael G Lattorff Vincent Laudet Cornelia von Levetsow Zhenyi Liu Rebekka Lutz Jeremy A Lynch Rodrigo Nunes da Fonseca Nico Posnien Rolf Reuter Siegfried Roth Joël Savard Johannes B Schinko Christian Schmitt Michael Schoppmeier Reinhard Schröder Teresa D Shippy Franck Simonnet Henrique Marques-Souza Diethard Tautz Yoshinori Tomoyasu Jochen Trauner Maurijn Van der Zee Michel Vervoort Nadine Wittkopp Ernst A Wimmer Xiaoyun Yang Andrew K Jones David B Sattelle Paul R Ebert David Nelson Jeffrey G Scott Richard W Beeman Subbaratnam Muthukrishnan Karl J Kramer Yasuyuki Arakane Richard W Beeman Qingsong Zhu David Hogenkamp Radhika Dixit Brenda Oppert Haobo Jiang Zhen Zou Jeremy Marshall Elena Elpidina Konstantin Vinokurov Cris Oppert Zhen Zou Jay Evans Zhiqiang Lu Picheng Zhao Niranji Sumathipala Boran Altincicek Andreas Vilcinskas Michael Williams Dan Hultmark Charles Hetru Haobo Jiang Cornelis J P Grimmelikhuijzen Frank Hauser Giuseppe Cazzamali Michael Williamson Yoonseong Park Bin Li Yoshiaki Tanaka Reinhard Predel Susanne Neupert Joachim Schachtner Peter Verleyen Florian Raible Peer Bork Markus Friedrich Kimberly K O Walden Hugh M Robertson Sergio Angeli Sylvain Forêt Gregor Bucher Stefan Schuetz Ryszard Maleszka Ernst A Wimmer Richard W Beeman Marce Lorenzen Yoshinori Tomoyasu Sherry C Miller Daniela Grossmann Gregor Bucher

Nature 2008 Apr 23;452(7190):949-55. Epub 2008 Mar 23.

Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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Structural Bioinformatics and Computational Biochemistry Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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Department of Physiology, Anatomy and Genetics, University of Oxford, UK.

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Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK.

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The Abeta1-42M35C mutated amyloid peptide Abeta1-42 and the 25-35 fragment fail to mimic the subtype-specificity of actions on recombinant human nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4).

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MRC Functional Genetics Unit, Department of Physiology, Anatomy and Genetics, Oxford University, South Parks Road, Oxford OX1 3QX, United Kingdom.

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MRC Functional Genetics Unit, Department of Physiology Anatomy and Genetics, The Sherrington Building, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature.

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Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford,UK.

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MRC Functional Genetics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Le Gros Clark Building, South Parks Road, Oxford, OX1 3QX, UK.

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Laboratoire Récepteurs et Canaux Ioniques Membranaires, UPRES EA 2647/USC INRA, Université d'Angers, UFR Sciences, 2 Boulevard Lavoisier, 49045 Angers cedex, France.

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Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.

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The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera.

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MRC Functional Genetics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom.

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Caenorhabditis elegans in the study of SMN-interacting proteins: a role for SMI-1, an orthologue of human Gemin2 and the identification of novel components of the SMN complex.

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Centre for Haematology, Bart's and The London, Queen Mary's School of Medicine, Institute of Cell and Molecular Science, 4 Newark Street, London, E1 2AT, UK.

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Gene expression profiling studies on Caenorhabditis elegans dystrophin mutants dys-1(cx-35) and dys-1(cx18).

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MRC Functional Genetics Unit, Department of Human Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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The cys-loop ligand-gated ion channel superfamily of the honeybee, Apis mellifera.

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Department of Physiology, Anatomy and Genetics, MRC Functional Genetics Unit, Le Gros Clark Building, University of Oxford, South Parks Road, Oxford, UK.

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SMN, the product of the spinal muscular atrophy-determining gene, is expressed widely but selectively in the developing human forebrain.

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MRC Functional Genetics Unit, Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, University of Oxford, Oxford OX1 3QX, United Kingdom.

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MRC Functional Genetics Unit, Department of Human Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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Effects of amyloid peptides on A-type K+ currents of Drosophila larval cholinergic neurons.

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Department of Human Anatomy and Genetics, MRC Functional Genetics Unit, University of Oxford, South Parks Road, Oxford OX1 3QX, United Kingdom.

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