David B Sacks

David B Sacks

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David B Sacks

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Diagnosis of Gestational Diabetes Mellitus Will Be Flawed until We Can Measure Glucose.

Clin Chem 2020 Feb;66(2):265-267

Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD.

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http://dx.doi.org/10.1093/clinchem/hvz027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055661PMC
February 2020

Insulin suppresses transcriptional activity of yes-associated protein in insulin target cells.

Mol Biol Cell 2020 01 6;31(2):131-141. Epub 2019 Nov 6.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD 20892.

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http://dx.doi.org/10.1091/mbc.E19-04-0205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960410PMC
January 2020

Ca-Dependent Switch of Calmodulin Interaction Mode with Tandem IQ Motifs in the Scaffolding Protein IQGAP1.

Biochemistry 2019 Dec 26;58(49):4903-4911. Epub 2019 Nov 26.

Center for Cancer Research, National Cancer Institute , National Institutes of Health , Frederick , Maryland 20892 , United States.

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http://dx.doi.org/10.1021/acs.biochem.9b00854DOI Listing
December 2019

Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis.

J Exp Med 2019 Nov 8;216(11):2582-2601. Epub 2019 Aug 8.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL

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http://dx.doi.org/10.1084/jem.20190008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829592PMC
November 2019

Point-of-Care Hemoglobin A1c.

JAMA 2019 Sep 12. Epub 2019 Sep 12.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jama.2019.14063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065945PMC
September 2019

The National Glycohemoglobin Standardization Program: Over 20 Years of Improving Hemoglobin A Measurement.

Clin Chem 2019 07 5;65(7):839-848. Epub 2018 Dec 5.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2018.296962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693326PMC
July 2019

Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras.

Sci Rep 2019 Jul 30;9(1):11057. Epub 2019 Jul 30.

From the Department of Laboratory Medicine, National Institutes of Health, 10 Center Drive, Bethesda, Maryland, 20892, USA.

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http://dx.doi.org/10.1038/s41598-019-46677-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667474PMC
July 2019

Abstracts of Presentations at the Association of Clinical Scientists 139 Meeting Hershey, PA, May 15-18, 2019.

Authors:
Keri Donaldson Jeanine M Buchanich Patricia Sue Grigson Erin Deneke Keri Donaldson Kent E Vrana David B Sacks Gregory J Kuehn David Cardamone Amadeo Pesce Sarah Smiley Joyce Nickley Kevin Krock Richard Thomas Myra L Wilkerson Hosam A Farag Sashi Rameswara Challa Ann Marie Tice Donna M Wolk Jeffrey Prichard Michelle L Grant Sandeep Regmi Brian Kerbacher Lawrence E Quinton Hosam A Farag A M Tice Donna M Wolk Jordan Olson Amanda Haynes Elsie Yu Kilmer S McCully Jasmeet Assi Myra Wong Neda Zarrin-Khameh Thomas P Nifong Charles D Hawker George T Carlton Julia M Rivera Philip R Foulis Aleksandra Zuraw Diana Morlote Deniz Peker Vishnu Reddy Shuko Harada Chris Crutchfield Dani Zander Mustafa A Barbhuiya Edward C Pederson Monica L Straub Sofia C Scott Terri L Neibauer Wayne F Salter Michael H Creer Yusheng Zhu Joshua A Bornhorst J Paul Theobald Alicia Algeciras-Schimnich Liyun Cao James Knox Robert Hardy Hicks J Texas Mary F McGuire Robert L Hunter Robert E Brown John Hicks John Hicks Zhenjian Cai Robert E Brown Yasir Ali Keith C Cheng Spencer R Katz Yifu Ding Daniel J Vanselow Maxsim A Yakovlev Alex Y Lin Darin P Clark Phillip Vargas Xuying Xin Jean E Copper Victor A Canfield Khai C Ang Yuxin Wang Xianghui Xiao Francesco De Carlo Damian B van Rossum Patrick J La Rivière Jordan Newell Carrie Hossler Michael Roche Joshua Warrick Rebecca Phaeton Josh Kesterson Keri Donaldson Charlotte Myers Roberto Barrios Paul Mintz Kimberly Robyak Christopher Hamilton Pamela McGhee Christopher Pederson Monica Straub Sofia Scott Terri Neibauer Wayne Salter Michael Creer Yusheng Zhu Christopher Hamilton Kimberly Robyak Pamela McGhee Christopher Pederson Monica Straub Sofia Scott Terri Neibauer Wayne Salter Michael Creer Yusheng Zhu Nirupama Singh Diana Morlote Cindy Vnencak-Jones Anna Yemelyanova Shuko Harada Mauli Shah Soheil Zorofchian Moghadamtousi Chieh Lan Dzifa Duose Peter Hu Yoshua Esquenazi Rajyalakshmi Luthra Leomar Y Ballester Annie N Koenig Chang-Gong Liu Jianhua Zhang Awdhesh Kalia Ali Al-Habib Melissa Van Arsdall Sadhna Dhingra Kalyani Patel Nina Tatevian

Ann Clin Lab Sci 2019 05;49(3):403-416

The University of Texas Health Science Center, Houston, TX.

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May 2019

Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α.

J Phys Chem B 2018 12 8;122(49):11137-11146. Epub 2018 Aug 8.

Cancer and Inflammation Program, Leidos Biomedical Research, Inc. , Frederick National Laboratory for Cancer Research Sponsored by the National Cancer Institute , Frederick , Maryland 21702 , United States.

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http://dx.doi.org/10.1021/acs.jpcb.8b05982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422767PMC
December 2018

IQGAP1 binds the Axl receptor kinase and inhibits its signaling.

Biochem J 2018 10 9;475(19):3073-3086. Epub 2018 Oct 9.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD 20892, U.S.A.

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http://dx.doi.org/10.1042/BCJ20180594DOI Listing
October 2018

Rapid Classification and Identification of Multiple Microorganisms with Accurate Statistical Significance via High-Resolution Tandem Mass Spectrometry.

J Am Soc Mass Spectrom 2018 Aug 5;29(8):1721-1737. Epub 2018 Jun 5.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.

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http://dx.doi.org/10.1007/s13361-018-1986-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061032PMC
August 2018

Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol.

Clin Chem 2018 05 7;64(5):843-850. Epub 2018 Feb 7.

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1373/clinchem.2017.285742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924648PMC
May 2018

Gestational Diabetes Mellitus: Why the Controversy?

Clin Chem 2018 03 11;64(3):431-438. Epub 2017 Oct 11.

Professor of Obstetrics and Gynecology, The Sackler Faculty of Medicine, Tel Aviv University, Helen Schneider's Hospital for Women, Rabin Medical Center, Petah-Tikva, Israel, President, European Association of Perinatal Medicine (EAPM), Chairman, FIGO Hyperglycemia in Pregnancy (HIP) Working Group.

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http://dx.doi.org/10.1373/clinchem.2016.266577DOI Listing
March 2018

Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2.

J Biol Chem 2018 03 22;293(10):3685-3699. Epub 2018 Jan 22.

the Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, NCI-Frederick, Frederick, Maryland 21702,

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http://dx.doi.org/10.1074/jbc.RA117.001596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846150PMC
March 2018

Refining Measurement of Hemoglobin A.

Clin Chem 2017 09 20;63(9):1433-1435. Epub 2017 Jun 20.

Biostatistics Center, George Washington University, Rockville MD.

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http://dx.doi.org/10.1373/clinchem.2016.268573DOI Listing
September 2017

Variability in the Relationship of Hemoglobin A1c and Average Glucose Concentrations: How Much Does Race Matter?

Ann Intern Med 2017 07 13;167(2):131-132. Epub 2017 Jun 13.

From Johns Hopkins Bloomberg School of Public Health, Baltimore, and National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.7326/M17-1231DOI Listing
July 2017

Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α.

J Biol Chem 2017 03 7;292(11):4614-4622. Epub 2017 Feb 7.

From the Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland 20892,

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http://dx.doi.org/10.1074/jbc.M116.754804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377777PMC
March 2017

Monitoring Glycemic Control in End-Stage Renal Disease: What Should Be Measured?

Clin Chem 2017 02 14;63(2):447-449. Epub 2016 Dec 14.

Department of Laboratory Medicine, NIH, Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2016.265744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337943PMC
February 2017

Absence of IQGAP1 Protein Leads to Insulin Resistance.

J Biol Chem 2017 02 12;292(8):3273-3289. Epub 2017 Jan 12.

From the Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland 20892

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http://www.jbc.org/lookup/doi/10.1074/jbc.M116.752642
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http://dx.doi.org/10.1074/jbc.M116.752642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336162PMC
February 2017

Association of Sickle Cell Trait With Hemoglobin A1c in African Americans.

JAMA 2017 02;317(5):507-515

Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island13Center for Innovation in Long-Term Services and Support, Providence Veterans Affairs Medical Center, Providence, Rhode Island14Division of Cardiology, Providence Veterans Affairs Medical Center, Providence, Rhode Island15Department of Medicine, Alpert Medical School, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1001/jama.2016.21035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713881PMC
February 2017

Agonist-stimulated phosphatidylinositol-3,4,5-trisphosphate generation by scaffolded phosphoinositide kinases.

Nat Cell Biol 2016 Dec 21;18(12):1324-1335. Epub 2016 Nov 21.

University of Wisconsin-Madison, School of Medicine and Public Health, 1300 University Avenue, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1038/ncb3441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679705PMC
December 2016

Glycated Albumin Identifies Prediabetes Not Detected by Hemoglobin A1c: The Africans in America Study.

Clin Chem 2016 Nov 13;62(11):1524-1532. Epub 2016 Sep 13.

Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2016.261255DOI Listing
November 2016

Hemoglobin A1c and Race: Should Therapeutic Targets and Diagnostic Cutoffs Differ among Racial Groups?

Authors:
David B Sacks

Clin Chem 2016 09 7;62(9):1199-201. Epub 2016 Jul 7.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2016.255166DOI Listing
September 2016

IQGAP1 Binds to Yes-associated Protein (YAP) and Modulates Its Transcriptional Activity.

J Biol Chem 2016 09 20;291(37):19261-73. Epub 2016 Jul 20.

From the Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland 20892

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http://dx.doi.org/10.1074/jbc.M116.732529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016668PMC
September 2016

The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.

Structure 2016 09 11;24(9):1499-508. Epub 2016 Aug 11.

Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014685PMC
September 2016

Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer.

PLoS One 2016 25;11(2):e0149383. Epub 2016 Feb 25.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149383PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767803PMC
July 2016

Higher degree of glycation of hemoglobin S compared to hemoglobin A measured by mass spectrometry: Potential impact on HbA1c testing.

Clin Chim Acta 2016 Jul 22;458:40-3. Epub 2016 Apr 22.

Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, MO, United States. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068909PMC
http://dx.doi.org/10.1016/j.cca.2016.04.027DOI Listing
July 2016

Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium.

J Tissue Eng Regen Med 2016 Feb 18;10(2):E84-9. Epub 2013 Apr 18.

Molecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/term.1743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883763PMC
February 2016

Identification of Microorganisms by High Resolution Tandem Mass Spectrometry with Accurate Statistical Significance.

J Am Soc Mass Spectrom 2016 Feb 28;27(2):194-210. Epub 2015 Oct 28.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.

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http://dx.doi.org/10.1007/s13361-015-1271-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723618PMC
February 2016

Detrimental Effects of Not Using International Reference Materials to Calibrate Cystatin C Assays.

Clin Chem 2016 Feb 9;62(2):410-1. Epub 2015 Nov 9.

Department of Laboratory Medicine Clinical Center National Institutes of Health Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2015.244988DOI Listing
February 2016

A1C Combined With Glycated Albumin Improves Detection of Prediabetes in Africans: The Africans in America Study.

Diabetes Care 2016 Feb 17;39(2):271-7. Epub 2015 Dec 17.

Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.2337/dc15-1699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876771PMC
February 2016

Midkine concentrations in fine-needle aspiration of benign and malignant thyroid nodules.

Clin Endocrinol (Oxf) 2015 Dec 15;83(6):977-84. Epub 2015 Jan 15.

Section on Growth and Development, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/cen.12676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532878PMC
December 2015

Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.

PLoS Pathog 2015 Oct 16;11(10):e1005200. Epub 2015 Oct 16.

Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Cambridge, Massachusetts, United States of America; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608727PMC
October 2015

Plasmonic chip tackles type 1 diabetes diagnosis.

Clin Chem 2015 Jun 5;61(6):794-6. Epub 2015 Feb 5.

Department of Laboratory Medicine, NIH, Bethesda, MD;

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http://dx.doi.org/10.1373/clinchem.2014.233346DOI Listing
June 2015

Evaluation of hemoglobin A1c measurement by Capillarys 2 electrophoresis for detection of abnormal glucose tolerance in African immigrants to the United States.

Clin Chim Acta 2015 Jun 8;446:54-60. Epub 2015 Apr 8.

Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2015.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449818PMC
June 2015

The biology of IQGAP proteins: beyond the cytoskeleton.

EMBO Rep 2015 Apr 26;16(4):427-46. Epub 2015 Feb 26.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD, USA

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http://dx.doi.org/10.15252/embr.201439834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388610PMC
April 2015

IQGAP1 controls tight junction formation through differential regulation of claudin recruitment.

J Cell Sci 2015 Mar 14;128(5):853-62. Epub 2015 Jan 14.

Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA

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http://dx.doi.org/10.1242/jcs.118703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342576PMC
March 2015

IQGAPs choreograph cellular signaling from the membrane to the nucleus.

Trends Cell Biol 2015 Mar 21;25(3):171-84. Epub 2015 Jan 21.

Department of Laboratory Medicine, National Institutes of Health, 10 Center Drive, Building 10, Room 2C306, Bethesda, MD 20892, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09628924140021
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http://dx.doi.org/10.1016/j.tcb.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344846PMC
March 2015

Interference of cerebrospinal fluid total protein measurement by povidone-iodine contamination.

Clin Chim Acta 2015 Feb 16;440:3-5. Epub 2014 Oct 16.

Department of Laboratory Medicine, NIH Clinical Center, Building 10, Room 2C-249, Bethesda, MD 20892 USA. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2014.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305459PMC
February 2015

Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier.

J Biol Chem 2015 Feb 9;290(7):4097-109. Epub 2014 Dec 9.

From the Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois 60637,

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http://dx.doi.org/10.1074/jbc.M114.620377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326819PMC
February 2015

Commentary.

Authors:
David B Sacks

Clin Chem 2014 Oct;60(10):1271-2

Department of Laboratory Medicine, NIH, Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2014.221408DOI Listing
October 2014

IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.

Mol Cell Biol 2014 Sep 14;34(18):3546-58. Epub 2014 Jul 14.

Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA

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http://dx.doi.org/10.1128/MCB.00248-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135611PMC
September 2014

A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions.

Cell Mol Life Sci 2014 Jul 19;71(14):2759-73. Epub 2013 Dec 19.

Division of Cancer Studies, King's College London, New Hunts House, Guys Campus, London, SE1 1UL, UK.

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http://dx.doi.org/10.1007/s00018-013-1528-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059965PMC
July 2014

The surveillance error grid.

J Diabetes Sci Technol 2014 Jul 13;8(4):658-72. Epub 2014 Jun 13.

University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1177/1932296814539589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764212PMC
July 2014

Comparing analytic performance criteria: evaluation of HbA1c certification criteria as an example.

Clin Chim Acta 2014 Jun 8;433:259-63. Epub 2014 Apr 8.

Department of Pathology & Anatomical Sciences, University of Missouri, Columbia School of Medicine, 1 Hospital Drive, Columbia, MO 65212, United States; Department of Child Health, University of Missouri, Columbia School of Medicine, 1 Hospital Drive, Columbia, MO 65212, United States.

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http://dx.doi.org/10.1016/j.cca.2014.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041663PMC
June 2014

Interpretation of hemoglobin A1c values.

JAMA 2014 Jun;311(22):2271-2

Department of Clinical Biochemistry, Norfolk and Norwich University Hospital, and Norwich Medical School, Norwich, United Kingdom.

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http://dx.doi.org/10.1001/jama.2014.6342DOI Listing
June 2014

Islet autoantibodies and type 1 diabetes: does the evidence support screening?

Clin Chem 2014 Mar 20;60(3):438-40. Epub 2013 Dec 20.

Washington University School of Medicine, Department of Pathology and Immunology, St. Louis, MO;

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http://dx.doi.org/10.1373/clinchem.2013.212381DOI Listing
March 2014

IQGAP1 binds to estrogen receptor-α and modulates its function.

J Biol Chem 2014 Mar 18;289(13):9100-12. Epub 2014 Feb 18.

From the Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1074/jbc.M114.553511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979404PMC
March 2014

Diagnosis of gestational diabetes mellitus: it is time for international consensus.

Authors:
David B Sacks

Clin Chem 2014 Jan 23;60(1):141-3. Epub 2013 Sep 23.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2013.206920DOI Listing
January 2014

Reporting hemoglobin A1c: do the units matter?

Authors:
David B Sacks

Clin Chem 2013 Oct 22;59(10):1427-9. Epub 2013 Jul 22.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1373/clinchem.2013.211227DOI Listing
October 2013

IQGAP1 is a novel phosphatidylinositol 4,5 bisphosphate effector in regulation of directional cell migration.

EMBO J 2013 Oct 27;32(19):2617-30. Epub 2013 Aug 27.

Cellular and Molecular Biology Graduate Program, University of Wisconsin-Madison, School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.1038/emboj.2013.191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791370PMC
October 2013

The Ras GTPase-activating-like protein IQGAP1 mediates Nrf2 protein activation via the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK pathway.

J Biol Chem 2013 Aug 20;288(31):22378-86. Epub 2013 Jun 20.

Graduate Program in Pharmaceutical Science, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1074/jbc.M112.444182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829328PMC
August 2013

Identification and functional studies of a new Nrf2 partner IQGAP1: a critical role in the stability and transactivation of Nrf2.

Antioxid Redox Signal 2013 Jul 17;19(2):89-101. Epub 2012 Sep 17.

Graduate Program in Pharmaceutical Science, Center for Cancer Prevention Research, Ernest-Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1089/ars.2012.4586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689176PMC
July 2013

Hemoglobin A1c in diabetes: panacea or pointless?

Authors:
David B Sacks

Diabetes 2013 Jan;62(1):41-3

Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.2337/db12-1485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526051PMC
January 2013

Comparing multiple measures of glycemia: how to transition from biomarker to diagnostic test?

Clin Chem 2012 Dec 31;58(12):1615-7. Epub 2012 Oct 31.

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http://dx.doi.org/10.1373/clinchem.2012.196139DOI Listing
December 2012

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.

Nature 2012 Dec 11;492(7427):123-7. Epub 2012 Nov 11.

Inflammatory Disease Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4175565PMC
December 2012

Measurement of hemoglobin A(1c): a new twist on the path to harmony.

Authors:
David B Sacks

Diabetes Care 2012 Dec;35(12):2674-80

Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.2337/dc12-1348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507560PMC
December 2012

IQGAP1 mediates the disruption of adherens junctions to promote Escherichia coli K1 invasion of brain endothelial cells.

Cell Microbiol 2012 Sep 24;14(9):1415-33. Epub 2012 May 24.

Division of Infectious Diseases, Department of Pediatrics, The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California School of Medicine, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1111/j.1462-5822.2012.01805.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410974PMC
September 2012

Measuring and reporting hemoglobin A1c.

Authors:
David B Sacks

Clin Biochem 2012 Sep 15;45(13-14):1046-7. Epub 2012 Jul 15.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD 20892, USA.

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September 2012

IQGAP1 and its binding proteins control diverse biological functions.

Cell Signal 2012 Apr 11;24(4):826-34. Epub 2011 Dec 11.

Department of Pathology, Beth Israel Deaconess Medical Centre and Harvard Medical School, 3 Blackfan Circle, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268868PMC
April 2012

Structural basis for Ca2+-induced activation and dimerization of estrogen receptor α by calmodulin.

J Biol Chem 2012 Mar 23;287(12):9336-44. Epub 2012 Jan 23.

Department of Chemistry, University of California, Davis, California 95616, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308758PMC
March 2012

Salmonella enterica serotype Typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAPK signalling.

Biochem J 2011 Dec;440(3):309-18

Department of Translational Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236857PMC
December 2011

AKAP220 protein organizes signaling elements that impact cell migration.

J Biol Chem 2011 Nov 2;286(45):39269-81. Epub 2011 Sep 2.

Howard Hughes Medical Institute, University of Washington School of Medicine, Seattle, Washington 98195, USA.

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November 2011

HbA(1c): what do the numbers really mean?

Lancet 2011 Sep;378(9796):1068-9; author reply 1069-70

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September 2011

IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance.

J Biol Chem 2011 Aug 1;286(34):29734-47. Epub 2011 Jul 1.

Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191015PMC
August 2011

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex.

Proc Natl Acad Sci U S A 2011 Jul 27;108(28):11381-6. Epub 2011 Jun 27.

Department of Pathology, Harvard Medical School, Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital Boston, Boston, MA 02115, USA.

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July 2011

Executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

Clin Chem 2011 Jun 26;57(6):793-8. Epub 2011 May 26.

Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD 20892-1508, USA.

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June 2011

Calmodulin binds HER2 and modulates HER2 signaling.

Biochim Biophys Acta 2011 May 24;1813(5):1074-82. Epub 2010 Dec 24.

Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079001PMC
May 2011

MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation.

J Biol Chem 2011 Apr 24;286(17):15010-21. Epub 2011 Feb 24.

Proteomic and Biological Mass Spectrometry Laboratory, GlaxoSmithKline, Collegeville, Pennsylvania 19426, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083173PMC
April 2011

IQGAP1 in microbial pathogenesis: Targeting the actin cytoskeleton.

FEBS Lett 2011 Mar 2;585(5):723-9. Epub 2011 Feb 2.

Department of Translational Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, Boston, MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085995PMC
March 2011

Gaps in the glycation gap hypothesis.

Clin Chem 2011 Feb 2;57(2):150-2. Epub 2010 Dec 2.

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February 2011

Status of hemoglobin A1c measurement and goals for improvement: from chaos to order for improving diabetes care.

Clin Chem 2011 Feb 9;57(2):205-14. Epub 2010 Dec 9.

Diabetes Diagnostic Laboratory M767, Department of Pathology and Anatomical Sciences, University of Missouri-Columbia School of Medicine, Columbia, MO 65212, USA.

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February 2011

Diabetes: advances and controversies.

Clin Chem 2011 Feb 13;57(2):147-9. Epub 2010 Dec 13.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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February 2011

A1C versus glucose testing: a comparison.

Authors:
David B Sacks

Diabetes Care 2011 Feb;34(2):518-23

Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.2337/dc10-1546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024379PMC
February 2011

Regulation of MAP kinase signaling by calcium.

Methods Mol Biol 2010 ;661:151-65

Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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December 2010

Point: The reporting of estimated glucose with hemoglobin A1c.

Clin Chem 2010 Apr 18;56(4):545-6. Epub 2010 Feb 18.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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April 2010

The Salmonella SPI2 effector SseI mediates long-term systemic infection by modulating host cell migration.

PLoS Pathog 2009 Nov 26;5(11):e1000671. Epub 2009 Nov 26.

Department of Microbiology and Immunology, Stanford University Medical Center, Stanford, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777311PMC
November 2009