David Allsop

David Allsop

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David Allsop

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Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis.

J Neurol 2019 Oct 15. Epub 2019 Oct 15.

Division of Neuroscience and Experimental Psychology, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s00415-019-09538-zDOI Listing
October 2019

Liposome delivery systems for the treatment of Alzheimer's disease.

Int J Nanomedicine 2018 12;13:8507-8522. Epub 2018 Dec 12.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, UK,

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http://dx.doi.org/10.2147/IJN.S183117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296687PMC
February 2019

Blood-based near-infrared spectroscopy for the rapid low-cost detection of Alzheimer's disease.

Analyst 2018 Dec;143(24):5959-5964

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.

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http://dx.doi.org/10.1039/c8an01205aDOI Listing
December 2018

Raman Spectroscopy to Diagnose Alzheimer's Disease and Dementia with Lewy Bodies in Blood.

ACS Chem Neurosci 2018 11 14;9(11):2786-2794. Epub 2018 Jun 14.

School of Pharmacy and Biomedical Sciences , University of Central Lancashire , Preston PR1 2HE , U.K.

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http://dx.doi.org/10.1021/acschemneuro.8b00198DOI Listing
November 2018

Medicinal cannabis in Australia, 2016: the Cannabis as Medicine Survey (CAMS-16).

Med J Aust 2018 08 13;209(5):211-216. Epub 2018 Aug 13.

Lambert Initiative for Cannabinoid Therapeutics, University of Sydney, Sydney, NSW.

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August 2018

Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes.

Interface Focus 2017 Dec 20;7(6):20160127. Epub 2017 Oct 20.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, University of Lancaster, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1098/rsfs.2016.0127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665791PMC
December 2017

α-Synuclein Interacts with Lipoproteins in Plasma.

J Mol Neurosci 2017 Oct 8;63(2):165-172. Epub 2017 Sep 8.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, University of Lancaster, Lancaster, LA1 4AY, UK.

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http://dx.doi.org/10.1007/s12031-017-0967-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674120PMC
October 2017

Differential diagnosis of Alzheimer's disease using spectrochemical analysis of blood.

Proc Natl Acad Sci U S A 2017 09 5;114(38):E7929-E7938. Epub 2017 Sep 5.

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1701517114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617251PMC
September 2017

Unravelling the evidence for prescribing medicinal cannabis.

Authors:
David Allsop

Med J Aust 2017 09;207(7):285

Lambert Initiative for Cannabinoid Therapeutics, University of Sydney, Sydney, NSW

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http://dx.doi.org/10.5694/mja17.00063DOI Listing
September 2017

An Australian nationwide survey on medicinal cannabis use for epilepsy: History of antiepileptic drug treatment predicts medicinal cannabis use.

Epilepsy Behav 2017 05 24;70(Pt B):334-340. Epub 2017 Feb 24.

Drug and Alcohol Services, South Eastern Sydney Local Health District New South Wales Ministry of Health, Sydney, Australia; Addiction Medicine, Central Clinical School, Faculty of Medicine, The University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1016/j.yebeh.2017.02.005DOI Listing
May 2017

Magnetite pollution nanoparticles in the human brain.

Proc Natl Acad Sci U S A 2016 09 6;113(39):10797-801. Epub 2016 Sep 6.

Neurotoxicology Laboratory, The University of Montana, Missoula, MT 59812; Universidad del Valle de México, Mexico City, 04850, Mexico.

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http://www.pnas.org/content/113/39/10797.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047173PMC
http://dx.doi.org/10.1073/pnas.1605941113DOI Listing
September 2016

Effects of different isoforms of apoE on aggregation of the α-synuclein protein implicated in Parkinson's disease.

Neurosci Lett 2016 Apr 24;618:146-151. Epub 2016 Feb 24.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, University of Lancaster, Lancaster LA1 4AY, UK.

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http://dx.doi.org/10.1016/j.neulet.2016.02.042DOI Listing
April 2016

Designed Glycopeptidomimetics Disrupt Protein-Protein Interactions Mediating Amyloid β-Peptide Aggregation and Restore Neuroblastoma Cell Viability.

J Med Chem 2016 Mar 4;59(5):2025-40. Epub 2016 Feb 4.

Molécules Fluorées et Chimie Médicinale, BioCIS, Univ. Paris-Sud, CNRS, Université Paris Saclay , 5 rue Jean-Baptiste Clément, 92296 Châtenay-Malabry Cedex, France.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01629DOI Listing
March 2016

Rapid elimination of Carboxy-THC in a cohort of chronic cannabis users.

Int J Legal Med 2016 Jan 2;130(1):147-52. Epub 2015 Aug 2.

Centre for Forensic Science, University of Technology Sydney (UTS), Broadway, Sydney, NSW, 2007, Australia.

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http://dx.doi.org/10.1007/s00414-015-1241-zDOI Listing
January 2016

The Effects of Lithium Carbonate Supplemented with Nitrazepam on Sleep Disturbance during Cannabis Abstinence.

J Clin Sleep Med 2015 Oct 15;11(10):1153-62. Epub 2015 Oct 15.

Discipline of Addiction Medicine, Central Clinical School, University of Sydney, NSW Australia.

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http://dx.doi.org/10.5664/jcsm.5090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582056PMC
October 2015

Amyloid β-peptide and Alzheimer's disease.

Essays Biochem 2014 ;56:99-110

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, U.K.

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http://dx.doi.org/10.1042/bse0560099DOI Listing
May 2015

Lithium carbonate in the management of cannabis withdrawal: a randomized placebo-controlled trial in an inpatient setting.

Psychopharmacology (Berl) 2014 Dec 1;231(24):4623-36. Epub 2014 Jun 1.

Discipline of Addiction Medicine, University of Sydney, Camperdown, NSW, 2050, Australia.

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http://dx.doi.org/10.1007/s00213-014-3611-5DOI Listing
December 2014

Fasting and exercise increase plasma cannabinoid levels in THC pre-treated rats: an examination of behavioural consequences.

Psychopharmacology (Berl) 2014 Oct 3;231(20):3987-96. Epub 2014 Apr 3.

The Discipline of Pharmacology, The University of Sydney, Darlington, NSW, 2006, Australia.

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http://dx.doi.org/10.1007/s00213-014-3532-3DOI Listing
October 2014

Dedicated 'cannabis only' treatment clinics in New South Wales, Australia: client and treatment characteristics and associations with first-time treatment seeking.

Drug Alcohol Rev 2014 Sep 6;33(5):565-71. Epub 2014 Jun 6.

National Cannabis Prevention and Information Centre, UNSW Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1111/dar.12166DOI Listing
September 2014

A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson's disease.

Sci Rep 2013 ;3:2540

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, University of Lancaster, Lancaster, LA1 4AY, UK.

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http://dx.doi.org/10.1038/srep02540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756331PMC
June 2014

Changes in cigarette and alcohol use during cannabis abstinence.

Drug Alcohol Depend 2014 May 12;138:54-60. Epub 2014 Feb 12.

National Cannabis Prevention and Information Centre, UNSW Medicine, Sydney 2052, Australia.

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http://dx.doi.org/10.1016/j.drugalcdep.2014.01.022DOI Listing
May 2014

The detection of THC, CBD and CBN in the oral fluid of Sativex® patients using two on-site screening tests and LC-MS/MS.

Forensic Sci Int 2014 May 12;238:113-9. Epub 2014 Mar 12.

National Cannabis Prevention and Information Centre, UNSW Medicine, Randwick 2031, NSW, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S03790738140009
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http://dx.doi.org/10.1016/j.forsciint.2014.03.004DOI Listing
May 2014

Six-month follow-up of Iranian women in methadone treatment: drug use, social functioning, crime, and HIV and HCV seroincidence.

Subst Abuse Rehabil 2012 2;3(Suppl 1):37-43. Epub 2012 Jan 2.

Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.2147/SAR.S21349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889184PMC
January 2014

Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples.

Neurosci Lett 2013 Sep 27;551:17-22. Epub 2013 Jun 27.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S030439401300576
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http://dx.doi.org/10.1016/j.neulet.2013.06.029DOI Listing
September 2013

Quantifying the clinical significance of cannabis withdrawal.

PLoS One 2012 26;7(9):e44864. Epub 2012 Sep 26.

National Cannabis Prevention and Information Centre, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044864PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458862PMC
April 2013

Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aβ oligomers.

Biochem Biophys Res Commun 2012 Jun 3;422(3):375-80. Epub 2012 May 3.

Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2012.04.146DOI Listing
June 2012

The Cannabis Withdrawal Scale development: patterns and predictors of cannabis withdrawal and distress.

Drug Alcohol Depend 2011 Dec 2;119(1-2):123-9. Epub 2011 Jul 2.

National Cannabis Prevention and Information Centre, University of New South Wales, Sydney 2031, Australia.

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http://dx.doi.org/10.1016/j.drugalcdep.2011.06.003DOI Listing
December 2011

Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease.

FASEB J 2011 Dec 24;25(12):4127-37. Epub 2011 Aug 24.

Division of Biomedical and Life Sciences, School of Health and Medicine, University of Lancaster, Lancaster, LA1 4AY, UK.

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http://dx.doi.org/10.1096/fj.10-179192DOI Listing
December 2011

Characteristics of Iranian women seeking drug treatment.

J Womens Health (Larchmt) 2011 Nov 9;20(11):1687-91. Epub 2011 Sep 9.

Program of International Research and Training, National Drug and Research Centre, University of New South Wales, Sydney 2052, Australia.

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http://dx.doi.org/10.1089/jwh.2010.2694DOI Listing
November 2011

Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide.

Nanomedicine 2011 Oct 29;7(5):541-50. Epub 2011 Jun 29.

Division of Biomedical and Life Sciences, School of Health and Medicine, University of Lancaster, Lancaster, UK.

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http://dx.doi.org/10.1016/j.nano.2011.06.015DOI Listing
October 2011

The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation.

Free Radic Biol Med 2011 Aug 2;51(4):869-75. Epub 2011 Jun 2.

Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.05.033DOI Listing
August 2011

Hypothesis: soluble aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease.

Int J Alzheimers Dis 2010 Nov 14;2011:546380. Epub 2010 Nov 14.

Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.4061/2011/546380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003964PMC
November 2010

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients.

FASEB J 2010 Aug 25;24(8):2716-26. Epub 2010 Mar 25.

Pharmacology Research Division, Takeda Pharmaceutical Company, Osaka, Japan.

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http://dx.doi.org/10.1096/fj.09-150359DOI Listing
August 2010

Computer-delivered interventions for alcohol and tobacco use: a meta-analysis.

Addiction 2010 Aug 28;105(8):1381-90. Epub 2010 May 28.

National Cannabis Prevention and Information Centre, University of New South Wales, Randwick, NSW 2031, Australia.

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http://dx.doi.org/10.1111/j.1360-0443.2010.02975.xDOI Listing
August 2010

Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

Biochemistry 2010 Apr;49(15):3261-72

Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1021/bi100144mDOI Listing
April 2010

Galantamine inhibits beta-amyloid aggregation and cytotoxicity.

J Neurol Sci 2009 May 26;280(1-2):49-58. Epub 2009 Feb 26.

Neurodegeneration Unit, Basic Medical Sciences, St. George's University of London, Cranmer Terrace, Tooting, London SW17 0RE, UK.

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http://dx.doi.org/10.1016/j.jns.2009.01.024DOI Listing
May 2009

Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies.

Brain 2009 Apr 20;132(Pt 4):1093-101. Epub 2009 Jan 20.

Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1093/brain/awn349DOI Listing
April 2009

Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

Acta Neuropathol 2009 Jan 7;117(1):55-62. Epub 2008 Nov 7.

Department of Neurology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, 602-0841, Japan.

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http://dx.doi.org/10.1007/s00401-008-0456-1DOI Listing
January 2009

Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease.

Biochem Soc Trans 2008 Dec;36(Pt 6):1293-8

Division of Biomedical and Life Sciences, School of Health and Medicine, Lancaster University, Lancaster, UK.

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http://dx.doi.org/10.1042/BST0361293DOI Listing
December 2008

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration.

Acta Neuropathol 2008 Aug 28;116(2):141-6. Epub 2008 May 28.

Division of Biomedical and Life Sciences, School of Health and Medicine, University of Lancaster, Lancaster, UK.

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http://dx.doi.org/10.1007/s00401-008-0389-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464623PMC
August 2008

Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's beta-amyloid peptide.

Biochemistry 2008 Feb 12;47(7):1984-92. Epub 2008 Jan 12.

Department of Basic Medical Sciences, St. George's Medical School, London SW17 ORE, United Kingdom.

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http://dx.doi.org/10.1021/bi701415bDOI Listing
February 2008

An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid.

Brain Res 2007 Sep 20;1170:103-11. Epub 2007 Jul 20.

Biomedical Sciences Unit, Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S000689930701653
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http://dx.doi.org/10.1016/j.brainres.2007.07.027DOI Listing
September 2007

Plasma amyloid-beta concentrations in Alzheimer's disease: an alternative hypothesis.

Lancet Neurol 2006 Dec;5(12):1000-1; author reply 1002-3

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http://dx.doi.org/10.1016/S1474-4422(06)70611-1DOI Listing
December 2006

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease.

Biochem Biophys Res Commun 2006 Oct 14;349(1):162-6. Epub 2006 Aug 14.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan, and Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbrc.2006.08.024DOI Listing
October 2006

Donepezil for severe Alzheimer's disease.

Lancet 2006 Jul;368(9533):361; author reply 362

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http://dx.doi.org/10.1016/S0140-6736(06)69097-1DOI Listing
July 2006

A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on beta-amyloid and alpha-synuclein.

Free Radic Res 2006 Jul;40(7):731-9

Magnetic Resonance Laboratory, Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1080/10715760600632545DOI Listing
July 2006

Industry: policing the 'dark side' of ecology.

Authors:
David Allsop

Nature 2006 Apr;440(7086):868

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http://dx.doi.org/10.1038/440868aDOI Listing
April 2006

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease.

FASEB J 2006 Mar;20(3):419-25

Department of Biochemistry, Faculty of Medicine and Health Science, United Arab Emirates University, Al Ain P. O. Box 17666, United Arab Emirates.

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http://dx.doi.org/10.1096/fj.03-1449comDOI Listing
March 2006

A dimensionless invariant for relative size at sex change in animals: explanation and implications.

Am Nat 2005 May 14;165(5):551-66. Epub 2005 Mar 14.

Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom.

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http://dx.doi.org/10.1086/429526DOI Listing
May 2005

Alpha-synuclein and the pathogenesis of Parkinson's disease.

Protein Pept Lett 2004 Jun;11(3):229-37

Department of Biological Sciences, I.E.N.S., Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.2174/0929866043407138DOI Listing
June 2004

Induction of cellular oxidative stress by the beta-amyloid peptide involved in Alzheimer's disease.

Protein Pept Lett 2004 Jun;11(3):257-70

Neurodegeneration Unit, Basic Medical Sciences, St. George's Hospital Medical School, Cranmer Terrace, Tooting, London SW17 0RE, UK.

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http://dx.doi.org/10.2174/0929866043407101DOI Listing
June 2004

Sex-ratio evolution in sex changing animals.

Evolution 2004 May;58(5):1019-27

Institute of Cell, Animal and Population Biology, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, EH9 3JT, United Kingdom.

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http://dx.doi.org/10.1111/j.0014-3820.2004.tb00435.xDOI Listing
May 2004

Both the D-(+) and L-(-) enantiomers of nicotine inhibit Abeta aggregation and cytotoxicity.

Biochemistry 2004 Jan;43(3):819-26

Department of Biological Sciences, University of Lancaster, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1021/bi035728hDOI Listing
January 2004

Life history: changing sex at the same relative body size.

Nature 2003 Oct;425(6960):783-4

Institute of Cell, Animal and Population Biology, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh EH9 3JT, UK.

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http://dx.doi.org/10.1038/425783aDOI Listing
October 2003

Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

Neuroreport 2003 Sep;14(13):1743-5

Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1097/00001756-200309150-00017DOI Listing
September 2003

Soluble oligomers for the diagnosis of neurodegenerative diseases.

Lancet Neurol 2003 Aug;2(8):461-2

Department of Biological Sciences, Lancaster University, Lancaster, UK.

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August 2003

Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.

Biochemistry 2003 Jul;42(25):7675-81

Department of Biological Sciences, University of Lancaster, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1021/bi030036eDOI Listing
July 2003

Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126.

Neurosci Lett 2003 Jan;336(3):159-62

Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK.

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http://dx.doi.org/10.1016/s0304-3940(02)01254-5DOI Listing
January 2003